Mercurial > repos > mzeidler > virana_main
view README @ 44:a8b31d446fec draft default tip
updated vhom regions with multiple hit file input and adapted visualization
| author | mzeidler |
|---|---|
| date | Mon, 04 Nov 2013 11:57:55 -0500 |
| parents | 53a6b7a0d10c |
| children |
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***Virana*** **The Virus Analysis Toolkit** Virana, the virus analysis toolkit, is a Python-based software toolkit for analyzing metatranscriptomic (and, to a degree, metagenomic) sequence data in a context of clinical metagenomics in order to: - identify pathogen nucleotide sequences in transcriptomic (and, while less tested, genomic) short read data - identify pathogen transcripts diverged from known references of various microbial species - identify transcripts expressed at low abundances across multiple samples - identify transcripts homologous to human factors such as certain viral oncogenes A recent analysis of human tumor transcriptomes displays the ability of Virana to detect diverged viral nucleotide sequences and human-viral homologs with high sensitivity. The manuscript is available at doi:10.1371/journal.pcbi.1003228 and http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003228 **Licence** For licence information see https://github.com/schelhorn/virana/raw/master/LICENSE **Installation** Using the virana tool shed repository, all dependencies are installed automatically. **Usage** There is an example workflow in the virana tool shed repository. Feel free to import the workflow and get familiar with the usage of the toolkit.
