view README @ 44:a8b31d446fec draft default tip

updated vhom regions with multiple hit file input and adapted visualization
author mzeidler
date Mon, 04 Nov 2013 11:57:55 -0500
parents 53a6b7a0d10c
children
line wrap: on
line source

***Virana***

**The Virus Analysis Toolkit**

Virana, the virus analysis toolkit, is a Python-based software toolkit for analyzing metatranscriptomic (and, to a degree, metagenomic) sequence data in a context of clinical metagenomics in order to:

    - identify pathogen nucleotide sequences in transcriptomic (and, while less tested, genomic) short read data
    - identify pathogen transcripts diverged from known references of various microbial species
    - identify transcripts expressed at low abundances across multiple samples
    - identify transcripts homologous to human factors such as certain viral oncogenes

A recent analysis of human tumor transcriptomes displays the ability of Virana to detect diverged viral nucleotide sequences and human-viral homologs with high sensitivity.
The manuscript is available at doi:10.1371/journal.pcbi.1003228 and http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003228


**Licence**

For licence information see https://github.com/schelhorn/virana/raw/master/LICENSE


**Installation**

Using the virana tool shed repository, all dependencies are installed automatically.


**Usage**

There is an example workflow in the virana tool shed repository. Feel free to import the workflow and get familiar with the usage of the toolkit.