Mercurial > repos > jjohnson > data_manager_snpeff
annotate data_manager/data_manager_snpEff_databases.py @ 5:78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
| author | Jim Johnson <jj@umn.edu> | 
|---|---|
| date | Tue, 13 Jan 2015 12:54:20 -0600 | 
| parents | c6769a700e55 | 
| children | a329eda0cdff | 
| rev | line source | 
|---|---|
| 0 | 1 #!/usr/bin/env python | 
| 2 | |
| 3 import sys | |
| 4 import os | |
| 5 import re | |
| 6 import tempfile | |
| 7 import subprocess | |
| 8 import fileinput | |
| 9 import shutil | |
| 10 import optparse | |
| 11 import urllib2 | |
| 12 from ftplib import FTP | |
| 13 import tarfile | |
| 14 | |
| 15 from galaxy.util.json import from_json_string, to_json_string | |
| 16 | |
| 17 def stop_err(msg): | |
| 18 sys.stderr.write(msg) | |
| 19 sys.exit(1) | |
| 20 | |
| 
5
 
78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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21 def getSnpeffVersion(jar_path): | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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22 snpeff_version = 'SnpEff ?.?' | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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23 (snpEff_dir,snpEff_jar) = os.path.split(jar_path) | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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24 stderr_path = 'snpeff.err' | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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25 stderr_fh = open(stderr_path,'w') | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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26 args = [ 'java','-jar', ] | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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27 args.append( snpEff_jar ) | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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28 args.append( '-h' ) | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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29 proc = subprocess.Popen( args=args, shell=False, cwd=snpEff_dir, stderr=stderr_fh.fileno() ) | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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30 return_code = proc.wait() | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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31 if return_code != 255: | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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32 sys.exit( return_code ) | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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33 stderr_fh.close() | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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34 fh = open(stderr_path,'r') | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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35 for line in fh: | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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36 m = re.match('^[Ss]npEff version (SnpEff)\s*(\d+\.\d+).*$',line) | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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37 if m: | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
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38 snpeff_version = m.groups()[0] + m.groups()[1] | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
 | 
39 break | 
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78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
 | 
40 fh.close() | 
| 
 
78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
 | 
41 return snpeff_version | 
| 
 
78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
 | 
42 | 
| 0 | 43 def fetch_databases(data_manager_dict, target_directory, jar_path): | 
| 44 (snpEff_dir,snpEff_jar) = os.path.split(jar_path) | |
| 45 if not os.path.exists(target_directory): | |
| 46 os.makedirs(target_directory) | |
| 47 databases_path = os.path.join( target_directory, 'databases.out' ) | |
| 48 databases_output = open(databases_path,'w') | |
| 49 args = [ 'java','-jar', ] | |
| 50 args.append( snpEff_jar ) | |
| 51 args.append( 'databases' ) | |
| 52 # tmp_stderr = tempfile.NamedTemporaryFile( prefix = "tmp-data-manager-snpEff-stderr" ) | |
| 53 # databases_output = open(databases_path) | |
| 54 # proc = subprocess.Popen( args=args, shell=False, cwd=snpEff_dir, stdout=databases_output.fileno(), stderr=tmp_stderr.fileno() ) | |
| 55 proc = subprocess.Popen( args=args, shell=False, cwd=snpEff_dir, stdout=databases_output.fileno() ) | |
| 56 return_code = proc.wait() | |
| 57 if return_code: | |
| 58 sys.exit( return_code ) | |
| 59 databases_output.close() | |
| 
5
 
78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
 | 
60 snpeff_version = getSnpeffVersion(jar_path) | 
| 0 | 61 try: | 
| 62 data_manager_dict['data_tables'] = data_manager_dict.get( 'data_tables', {} ) | |
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5
 
78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
 | 
63 data_manager_dict['data_tables']['snpeffv_databases'] = data_manager_dict['data_tables'].get( 'snpeffv_databases', [] ) | 
| 0 | 64 data_table_entries = [] | 
| 65 fh = open(databases_path,'r') | |
| 66 for i,line in enumerate(fh): | |
| 67 fields = line.split('\t') | |
| 68 if len(fields) >= 2: | |
| 69 genome_version = fields[0].strip() | |
| 70 if genome_version.startswith("Genome") or genome_version.startswith("-"): | |
| 71 continue | |
| 72 #snpeff test genome | |
| 73 if genome_version == '30c2c903' or fields[1].strip() == 'TestCase' or fields[1].strip().startswith('Test_'): | |
| 74 continue | |
| 75 description = fields[1].strip() + ' : ' + genome_version | |
| 
5
 
78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
 | 
76 key = snpeff_version + '_' + genome_version | 
| 
 
78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
 | 
77 data_table_entries.append(dict(key=key, version=snpeff_version, value=genome_version, name=description)) | 
| 
 
78bcf4ac437c
Use tool_data_table with key and version columns added to allow for multiple versions in a .loc file
 
Jim Johnson <jj@umn.edu> 
parents: 
3 
diff
changeset
 | 
78 data_manager_dict['data_tables']['snpeffv_databases'] = data_table_entries | 
| 0 | 79 except Exception, e: | 
| 80 stop_err( 'Error parsing %s %s\n' % (config,str( e )) ) | |
| 81 else: | |
| 82 fh.close() | |
| 83 return data_manager_dict | |
| 84 | |
| 85 def main(): | |
| 86 #Parse Command Line | |
| 87 parser = optparse.OptionParser() | |
| 88 parser.add_option( '-j', '--jar_path', dest='jar_path', action='store', type="string", default=None, help='snpEff.jar path' ) | |
| 89 (options, args) = parser.parse_args() | |
| 90 | |
| 91 filename = args[0] | |
| 92 | |
| 93 params = from_json_string( open( filename ).read() ) | |
| 94 target_directory = params[ 'output_data' ][0]['extra_files_path'] | |
| 95 os.mkdir( target_directory ) | |
| 96 data_manager_dict = {} | |
| 97 | |
| 98 | |
| 99 #Create Defuse Reference Data | |
| 100 data_manager_dict = fetch_databases( data_manager_dict, target_directory, options.jar_path) | |
| 101 | |
| 102 #save info to json file | |
| 103 open( filename, 'wb' ).write( to_json_string( data_manager_dict ) ) | |
| 104 | |
| 105 if __name__ == "__main__": main() | |
| 106 | 
