Mercurial > repos > iuc > dropletutils
changeset 0:1335bf5bcd0e draft
planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/dropletutils/ commit e66ab3d4fc0c1a72523e8f93447cc07cdd6816b7
| author | iuc |
|---|---|
| date | Tue, 04 Jun 2019 17:19:16 -0400 |
| parents | |
| children | 94ee8160ace3 |
| files | dropletutils.xml scripts/dropletutils.Rscript scripts/generateTestData.Rscript test-data/defs_barcoderankings.png test-data/defs_defaultdrops.h5ad test-data/defs_emptydrops_150_0002.h5ad test-data/defs_emptydrops_150_0002.png test-data/defs_emptydrops_150_0002a.h5ad test-data/defs_emptydrops_150_0002a.png test-data/in_barcodes.tsv test-data/in_genes.tsv test-data/in_matrix.h5ad test-data/in_matrix.mtx test-data/in_matrix.tsv |
| diffstat | 14 files changed, 61150 insertions(+), 0 deletions(-) [+] |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/dropletutils.xml Tue Jun 04 17:19:16 2019 -0400 @@ -0,0 +1,310 @@ +<?xml version="1.0" encoding="utf-8"?> +<tool id="dropletutils" name="DropletUtils" version="@PACKAGE_VERSION@+@GALAXY_VERSION@" > + <description>Utilities for handling droplet-based single-cell RNA-seq data</description> + <macros> + <token name="@PACKAGE_VERSION@" >1.2.1</token> + <token name="@GALAXY_VERSION@" >1</token> + <token name="@TXIN@">tenx.input</token> + <token name="@TXOUT@">tenx.output</token> + <xml name="test_dirin" > + <conditional name="tenx_format"> + <param name="use" value="directory" /> + <param name="input" value="in_matrix.mtx" /> + <param name="input_genes" value="in_genes.tsv" /> + <param name="input_barcodes" value="in_barcodes.tsv" /> + </conditional> + </xml> + </macros> + <requirements> + <requirement type="package" version="@PACKAGE_VERSION@">bioconductor-dropletutils</requirement> + <requirement type="package" version="1.2_17" >r-matrix</requirement> + </requirements> + <version_command><![CDATA[ + Rscript -e 'packageVersion("DropletUtils")' | grep -oP '\d\.\d\.\d' + ]]> + </version_command> + <command detect_errors='exit_code'><![CDATA[ +#if str($tenx_format.use) == 'directory': + mkdir '@TXIN@' && + ln -s '$tenx_format.input' '@TXIN@/matrix.mtx' && + ln -s '$tenx_format.input_genes' '@TXIN@/genes.tsv' && + ln -s '$tenx_format.input_barcodes' '@TXIN@/barcodes.tsv' && +#end if + +#if str($operation.use) == 'filter': + #if str($operation.outformat) == 'directory': + mkdir '@TXOUT@' && + #end if +#end if + +Rscript '$__tool_directory__/scripts/dropletutils.Rscript' '$droplet_conf' + ]]> + </command> + <configfiles> + <configfile name="droplet_conf" > +## defaults +empty.fdr_threshold = 0.01 +eparams=formals(emptyDrops) +dparams=formals(defaultDrops) +bparams=formals(barcodeRanks) + +## File params +in.type='$tenx_format.use' +out.type=NULL + +files=list() +files\$table='$table' +files\$plot='$plot' +files\$out=NULL + +#if str($tenx_format.use) == 'directory': +files\$infile='@TXIN@' +#else +files\$infile='$input' +#end if + +#if str($operation.use) == 'filter': + #if str($operation.method.use) == 'defaultdrops': +do.method="defaultDrops" +dparams\$expected=as.integer('$operation.method.expected') +dparams\$upper.quant=as.numeric('$operation.method.upperquant') +dparams\$lower.prop=as.numeric('$operation.method.lowerprop') + #else if str($operation.method.use) == 'emptydrops': +do.method="emptyDrops" +eparams\$lower=as.integer('$operation.method.lower') +empty.fdr_threshold=as.numeric('$operation.method.fdr_thresh') + #end if + +out.type='$operation.outformat' + #if str($operation.outformat) == 'directory': +files\$out='@TXOUT@' + #else if str($operation.outformat) == 'h5ad': +files\$out='$fileout_h5ad' + #else if str($operation.outformat) == 'tsv': +files\$out='$fileout_tsv' + #end if + +#else if str($operation.use) == 'barcode_rank': +do.method="barcodeRankings" +bparams\$lower=as.integer('$operation.lower') +#end if + +seed.val=as.integer('$seed') + + </configfile> + </configfiles> + <inputs> + <conditional name="tenx_format"> + <param name="use" type="select" label="Format for the input matrix"> + <option value="directory" >Bundled (barcodes.tsv, genes.tsv, matrix.mtx)</option> + <option value="h5ad" selected="true" >AnnData/H5</option> + <option value="tsv">Tabular</option> + </param> + <when value="directory"> + <param name="input" type="data" format="mtx,txt" label="Count Data"/> + <param name="input_genes" type="data" format="tabular,tsv,txt" label="Genes List"/> + <param name="input_barcodes" type="data" format="tabular,tsv,txt" label="Barcodes List"/> + </when> + <when value="h5ad"> + <param name="input" type="data" format="h5ad" label="Count Data"/> + </when> + <when value="tsv"> + <param name="input" type="data" format="tabular,tsv" label="Count Data" help="The first column must contain gene names, and the first row must contain barcode identifiers." /> + </when> + </conditional> + <conditional name="operation" > + <param name="use" type="select" label="Operation" help="The filtering uses intelligent methods to generate output 10X matrices as would be otherwise generated by CellRanger. The ranking option serves to illustrate the number of detected barcodes in the sample."> + <option value="filter" selected="true">Filter for Barcodes</option> + <option value="barcode_rank">Rank Barcodes</option> + </param> + <when value="filter"> + <conditional name="method"> + <param name="use" type="select" label="Method" help="The DefaultDrops method calls cells according to the number of UMIs associated with each barcode as implemented by CellRanger. The EmptyDrops method identifies empty droplets using a smart ambient background model." > + <option value="defaultdrops" selected="true">DefaultDrops</option> + <option value="emptydrops">EmptyDrops</option> + </param> + <when value="defaultdrops"> + <param name="expected" type="integer" min="10" value="3000" label="Expected Number of Cells" help="The expected number of cells in the sample." /> + <param name="upperquant" type="float" min="0.1" max="1.0" value="0.99" label="Upper Quantile" help="The quantile of the top expected barcodes to consider." /> + <param name="lowerprop" type="float" min="0.1" max="1.0" value="0.1" label="Lower Proportion" help="The fraction of molecules of the upper quantile that must be exceeded for a cell barcode to be detected." /> + </when> + <when value="emptydrops"> + <param name="lower" type="integer" min="10" value="100" label="Lower-bound Threshold" help="The lower-bound threshold of the total UMI count at which barcodes beneath this are assumed to be empty droplets." /> + <param name="fdr_thresh" type="float" min="0" max="1" value="0.01" label="FDR Threshold" help="False Discovery Rate threshold at which droplets with significant deviations from the ambient profile are detected at this threshold." /> + </when> + </conditional> + <param name="outformat" type="select" label="Format for output matrices"> + <option value="directory" >Bundled (barcodes.tsv, genes.tsv, matrix.mtx)</option> + <option value="h5ad" selected="true" >AnnData/H5</option> + <option value="tsv">Tabular</option> + </param> + </when> + <when value="barcode_rank"> + <param name="lower" type="integer" min="10" value="100" label="Lower Bound" help="Lower bound on the total UMI count, at or below which all barcodes are assumed to correspond to empty droplets."/> + </when> + </conditional> + <param name="seed" type="integer" value="100" label="Random Seed" /> + </inputs> + <outputs> + <data name="fileout_tsv" format="tsv" label="${tool.name} Count Matrix on ${on_string}"> + <filter>operation['use']=='filter' and operation['outformat'] == 'tsv' </filter> + </data> + <data name="fileout_h5ad" format="h5ad" label="${tool.name} AnnData on ${on_string}"> + <filter>operation['use']=='filter' and operation['outformat'] == 'h5ad'</filter> + </data> + <data name="barcodes_out" format="tsv" from_work_dir="@TXOUT@/barcodes.tsv" label="${tool.name} 10X Barcodes on ${on_string}" > + <filter>operation['use']=='filter' and operation['outformat'] == 'directory'</filter> + </data> + <data name="genes_out" format="tsv" from_work_dir="@TXOUT@/genes.tsv" label="${tool.name} 10X Genes on ${on_string}" > + <filter>operation['use']=='filter' and operation['outformat'] == 'directory'</filter> + </data> + <data name="matrix_out" format="mtx" from_work_dir="@TXOUT@/matrix.mtx" label="${tool.name} 10X Matrices on ${on_string}" > + <filter>operation['use']=='filter' and operation['outformat'] == 'directory'</filter> + </data> + <data name="plot" format="png" label="${tool.name} Plot on ${on_string}"> + <filter>(operation['use']=='filter' and operation['method']['use']=="emptydrops") or operation['use']=='barcode_rank'</filter> + </data> + <data name="table" format="tsv" label="${tool.name} Table on ${on_string}"> + <filter>operation['use']=='filter' and operation['method']['use']=="emptydrops"</filter> + </data> + </outputs> + <tests> + <!-- Directory input tests --> + <!-- ::: Default Drops --> + <test expect_num_outputs="1"> + <expand macro="test_dirin" /> + <conditional name="operation"> + <param name="use" value="filter" /> + <param name="outformat" value="h5ad" /><!-- H5AD --> + </conditional> + <output name="fileout_h5ad" value="defs_defaultdrops.h5ad" compare="sim_size" delta="10" /> + </test> + <test expect_num_outputs="1"> + <expand macro="test_dirin" /> + <conditional name="operation"> + <param name="use" value="filter" /> + <param name="outformat" value="tsv" /><!-- TSV --> + </conditional> + <output name="fileout_tsv" > + <assert_contents> + <has_n_columns n="1026" /> + <has_text_matching expression="^\sTCGCCAAGAA\sGGACTTAGAA\sTGCGCCTGAA\sACGGACACAA\sGCGGACACAA" /> + <has_text_matching expression="GENE50\s4\s0\s0\s0\s0\s5\s11\s8\s5" /> + <has_text_matching expression="GENE100\s6\s3\s5\s0\s0\s16\s31\s15\s26" /> + </assert_contents> + </output> + </test> + <!-- :: Barcode Ranks --> + <test expect_num_outputs="1"> + <expand macro="test_dirin" /> + <conditional name="operation"> + <param name="use" value="barcode_rank" /> + <param name="lower" value="120" /> + </conditional> + <output name="plot" value="defs_barcoderankings.png" compare="sim_size" delta="200"/> + </test> + <!-- ::: Empty Drops --> + <test expect_num_outputs="3"> + <expand macro="test_dirin" /> + <conditional name="operation"> + <param name="use" value="filter" /> + <param name="outformat" value="h5ad" /> + <conditional name="method"> + <param name="use" value="emptydrops" /> + <param name="lower" value="150" /> + <param name="fdr_thresh" value="0.02" /> + </conditional> + </conditional> + <output name="fileout_h5ad" value="defs_emptydrops_150_0002.h5ad" compare="sim_size" delta="10" /> + <output name="table" > + <assert_contents> + <has_n_columns n="9" /> + <has_line_matching expression="^\sbar.names\sTotal\sLogProb\sPValue\sLimited\sFDR\sis.Cell\sis.CellAndLimited" /> + <has_line_matching expression="^1\sGGAAGAAGAA\s0\sNA\sNA\sNA\sNA\sNA\sNA" /> + <has_line_matching expression="^11100\sGCTGAAGCAA\s71\sNA\sNA\sNA\sNA\sNA\sNA" /> + </assert_contents> + </output> + <output name="plot" value="defs_emptydrops_150_0002.png" compare="sim_size" delta="100" /> + </test> + <!-- Other format input tests --> + <!-- ::: Empty Drops, same as above but input is h5ad --> + <test expect_num_outputs="3"> + <conditional name="tenx_format" > + <param name="use" value="h5ad" /> + <param name="input" value="in_matrix.h5ad" /> + </conditional> + <conditional name="operation"> + <param name="use" value="filter" /> + <param name="outformat" value="h5ad" /> + <conditional name="method"> + <param name="use" value="emptydrops" /> + <param name="lower" value="150" /> + <param name="fdr_thresh" value="0.02" /> + </conditional> + </conditional> + <output name="fileout_h5ad" value="defs_emptydrops_150_0002a.h5ad" compare="sim_size" delta="200" /> + <output name="table" > + <assert_contents> + <has_n_columns n="9" /> + <has_line_matching expression="^\sbar.names\sTotal\sLogProb\sPValue\sLimited\sFDR\sis.Cell\sis.CellAndLimited" /> + <has_line_matching expression="^1\sGGAAGAAGAA\s20\sNA\sNA\sNA\sNA\sNA\sNA" /> + <has_line_matching expression="^11100\sGCTGAAGCAA\s203\s-222.833111872316\s9.99900009999e-05\sTRUE\s0.000126279506880773\sTRUE\sTRUE" /> + </assert_contents> + </output> + <output name="plot" value="defs_emptydrops_150_0002a.png" compare="sim_size" delta="100" /> + </test> + <!-- Output a directory --> + <test expect_num_outputs="3"> + <conditional name="tenx_format" > + <param name="use" value="tsv" /> + <param name="input" value="in_matrix.tsv" /> + </conditional> + <conditional name="operation"> + <param name="use" value="filter" /> + <param name="outformat" value="directory" /> + <conditional name="method"> + <param name="use" value="defaultdrops" /> + <param name="expected" value="2000" /> + <param name="upperquant" value="0.85" /> + <param name="lowerpopr" value="0.2" /> + </conditional> + </conditional> + <output name="genes_out" file="in_genes.tsv" ftype="tsv" /><!-- same as the input in this case --> + <output name="barcodes_out" ftype="tsv" > + <assert_contents> + <has_n_columns n="1" /> + <has_line line="GGAAGAAGAA" /> + <has_line line="TCGAATGGAA" /> + </assert_contents> + </output> + <output name="matrix_out" ftype="mtx" > + <assert_contents> + <has_line_matching expression="^100\s2650\s64072$" /> + <has_line_matching expression="^19\s1\s1$" /> + <has_line_matching expression="^100\s2650\s1$" /> + </assert_contents> + </output> + </test> + </tests> + <help><![CDATA[ +Utilities to process 10X data in a variety of formats. Methods include: + +*Filter data:* + +* **DefaultDrops** emulates the native 10X method to produce a filtered count matrix +* **EmptyDrops** is a more informative quantile-based approach to produce a filtered count matrix. + +*Metrics:* + +* **RankBarcodes** produces a gap statistic plot to estimate the number of barcodes detected in the sample matrix. + +*Background* + +Droplet-based single-cell RNA sequencing (scRNA-seq) technologies allow researchers to obtain transcriptome-wide expression profiles for thousands of cells at once. Briefly, each cell is encapsulated in a droplet in a oil-water emulsion, along with a bead containing reverse transcription primers with a unique barcode sequence. After reverse transcription inside the droplet, each cell’s cDNA is labelled with that barcode (referred to a “cell barcode”). Bursting of the droplets yields a pool of cDNA for library preparation and sequencing. Debarcoding of the sequences can then be performed to obtain the expression profile for each cell. + +This tool implements some general utilities for handling these data after quantification of expression. In particular, we focus on the 10X Genomics platform, providing functions to load in the matrix of unique molecule identifier (UMI) counts as well as the raw molecule information. Functions are also available for downsampling the UMI count matrix or the raw reads; for distinguishing cells from empty droplets, based on the UMI counts; and to eliminate the effects of barcode swapping on Illumina 4000 sequencing machine. +]]></help> + <citations> + <citation type="doi">10.1186/s13059-019-1662-y</citation> + </citations> +</tool>
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/scripts/dropletutils.Rscript Tue Jun 04 17:19:16 2019 -0400 @@ -0,0 +1,137 @@ +## Load in data +args = commandArgs(trailingOnly = T) +if (length(args) != 1){ + stop("Please provide the config file") +} + +suppressWarnings(suppressPackageStartupMessages(require(DropletUtils))) +suppressWarnings(suppressPackageStartupMessages(require(Matrix))) + +source(args[1]) + +## Helper functions +setSparse <- function(obj){ + return(as(obj, "dgCMatrix")) +} + +writeTSV <- function(fileout, obj){ + write.table(as.matrix(obj), file=fileout, col.names=NA, sep='\t', quote=FALSE) +} + +writeOut <- function(counts, fileout, typeout){ + if (typeout == "tsv"){ + writeTSV(fileout, counts) + } + else if (typeout == "h5ad"){ + write10xCounts(fileout, counts, type="HDF5", overwrite=TRUE) + } + else if (typeout == "directory"){ + write10xCounts(fileout, counts, type="sparse", overwrite=TRUE) + } +} + + +read10xFiles <- function(filein, typein){ + sce <- NULL + if (typein == "tsv"){ + dat <- read.table(filein, header = TRUE, sep='\t', stringsAsFactors=FALSE, quote="", row.names=1) + sce <- SingleCellExperiment(assays = list(counts = as.matrix(dat))) + } + else if (typein == "h5ad"){ + sce <- read10xCounts(filein, col.names=T, type="HDF5") # use barcodes.tsv as column names + } + else if (typein == "directory"){ + sce <- read10xCounts(filein, col.names=T, type="sparse") + } + counts(sce) <- setSparse(counts(sce)) + return(sce) +} + + +## Methods + + +doEmptyDrops <- function(files, eparams, in.type="directory", out.type="h5ad", fdr_threshold = 0.01){ + sce <- read10xFiles(files$infile, in.type) + + eparams$... <- NULL ## hack + eparams$m = Matrix(counts(sce), sparse=TRUE) + + e.out <- do.call(emptyDrops, c(eparams)) + + bar.names <- colnames(sce) + if (length(bar.names) != nrow(e.out)){ + stop("Length of barcodes and output metrics don't match.") + } + e.out <- cbind(bar.names, e.out) + e.out$is.Cell <- e.out$FDR <= fdr_threshold + e.out$is.CellAndLimited <- e.out$is.Cell & e.out$Limited + + # Write to table + writeTSV(files$table, e.out) + + # Print to log + print(table(Limited=e.out$Limited, Significant=e.out$is.Cell)) + + # Write to Plot + png(files$plot) + plot(e.out$Total, -e.out$LogProb, col=ifelse(e.out$is.Cell, "red", "black"), + xlab="Total UMI count", ylab="-Log Probability") + dev.off() + + # Filtered + called <- e.out$is.CellAndLimited + called[is.na(called)] <- FALSE # replace NA's with FALSE + sce.filtered <- sce[,called] + + writeOut(counts(sce.filtered), files$out, out.type) +} + + +doDefaultDrops <- function(files, dparams, in.type="directory", out.type="h5ad"){ + sce <- read10xFiles(files$infile, in.type) + + dparams$m = as.matrix(counts(sce)) + called <- do.call(defaultDrops, c(dparams)) + print(table(called)) + + # Filtered + sce.filtered <- sce[,called] + + writeOut(Matrix(counts(sce.filtered),sparse=TRUE), files$out, out.type) +} + + +doBarcodeRankings <- function(files, bparams, in.type="directory"){ + sce <- read10xFiles(files$infile, in.type) + + bparams$... <- NULL ## hack + bparams$m = as.matrix(counts(sce)) + + br.out <- do.call(barcodeRanks, c(bparams)) + + png(files$plot) + plot(br.out$rank, br.out$total, log="xy", xlab="(log) Rank", ylab="(log) Total Number of Barcodes") + o <- order(br.out$rank) + lines(br.out$rank[o], br.out$fitted[o], col="red") + + abline(h=br.out$knee, col="dodgerblue", lty=2) + abline(h=br.out$inflection, col="forestgreen", lty=2) + legend("bottomleft", lty=2, col=c("dodgerblue", "forestgreen"), legend=c("knee", "inflection")) + dev.off() + + print(paste("knee =", br.out$knee, ", inflection = ", br.out$inflection)) +} + +## Main +set.seed(seed.val) + +if (do.method == "barcodeRankings") { + doBarcodeRankings(files, bparams, in.type) + +} else if (do.method == "defaultDrops") { + doDefaultDrops(files, dparams, in.type, out.type) + +} else if (do.method == "emptyDrops") { + doEmptyDrops(files, eparams, in.type, out.type, empty.fdr_threshold) +}
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/scripts/generateTestData.Rscript Tue Jun 04 17:19:16 2019 -0400 @@ -0,0 +1,38 @@ +## +## conda install bioconductor-dropletutils bioconductor-dnabarcodes +## + +suppressWarnings(suppressPackageStartupMessages(library(DropletUtils))) +suppressWarnings(suppressPackageStartupMessages(library(DNABarcodes))) +library(Matrix) + +## Matrix with no column barcodes +set.seed(100) +##my.counts <- DropletUtils:::simCounts() +my.counts <- DropletUtils:::simCounts(large.rate=0.01, nlarge=500, nsmall=50, nempty=500) + +## Generate barcodes (size=10, edit=3) and set as headers +barcodes <- create.pool(10) +colnames(my.counts) <- barcodes[1:ncol(my.counts)] + +sce <- SingleCellExperiment(assays = list(counts = as.matrix(my.counts))) + +writeTSV <- function(fileout, obj){ + write.table(as.matrix(obj), file=fileout, col.names=NA, sep='\t', quote=FALSE) +} + +writeOut <- function(counts, fileout, typeout){ + if (typeout == "tsv"){ + writeTSV(fileout, counts) + } + else if (typeout == "h5ad"){ + write10xCounts(fileout, counts, type="HDF5", overwrite=TRUE) + } + else if (typeout == "directory"){ + write10xCounts(fileout, Matrix(counts), type="sparse", overwrite=TRUE) + } +} + +writeOut(Matrix(counts(sce)), "test-data", type="directory") +writeOut(counts(sce), "test-data.h5ad", type="h5ad") +writeOut(counts(sce), "test-data.tsv", type="tsv")
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/in_barcodes.tsv Tue Jun 04 17:19:16 2019 -0400 @@ -0,0 +1,11100 @@ +GGAAGAAGAA +CGAAGAAGAA +GCAAGAAGAA +CCAAGAAGAA +GAGAGAAGAA +CAGAGAAGAA +AGGAGAAGAA +CGGAGAAGAA +TGGAGAAGAA +ACGAGAAGAA +GCGAGAAGAA +CCGAGAAGAA +TCGAGAAGAA +GTGAGAAGAA +CTGAGAAGAA +GACAGAAGAA +CACAGAAGAA +AGCAGAAGAA +GGCAGAAGAA +CGCAGAAGAA +TGCAGAAGAA +ACCAGAAGAA +GCCAGAAGAA +TCCAGAAGAA +GTCAGAAGAA +CTCAGAAGAA +GGTAGAAGAA +CGTAGAAGAA +GCTAGAAGAA +CCTAGAAGAA +GAAGGAAGAA +CAAGGAAGAA +AGAGGAAGAA +GGAGGAAGAA +CGAGGAAGAA +TGAGGAAGAA +ACAGGAAGAA +GCAGGAAGAA +CCAGGAAGAA +TCAGGAAGAA +GTAGGAAGAA +CTAGGAAGAA +AACGGAAGAA +GACGGAAGAA +CACGGAAGAA +TACGGAAGAA +AGCGGAAGAA +GGCGGAAGAA +CGCGGAAGAA +TGCGGAAGAA +ACCGGAAGAA +GCCGGAAGAA +TCCGGAAGAA +ATCGGAAGAA +GTCGGAAGAA +CTCGGAAGAA +TTCGGAAGAA +GATGGAAGAA +CATGGAAGAA +AGTGGAAGAA +GGTGGAAGAA +CGTGGAAGAA +TGTGGAAGAA +ACTGGAAGAA +GCTGGAAGAA +CCTGGAAGAA +TCTGGAAGAA +GTTGGAAGAA +CTTGGAAGAA +GAACGAAGAA +CAACGAAGAA +AGACGAAGAA 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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/in_genes.tsv Tue Jun 04 17:19:16 2019 -0400 @@ -0,0 +1,100 @@ +GENE1 GENE1 +GENE2 GENE2 +GENE3 GENE3 +GENE4 GENE4 +GENE5 GENE5 +GENE6 GENE6 +GENE7 GENE7 +GENE8 GENE8 +GENE9 GENE9 +GENE10 GENE10 +GENE11 GENE11 +GENE12 GENE12 +GENE13 GENE13 +GENE14 GENE14 +GENE15 GENE15 +GENE16 GENE16 +GENE17 GENE17 +GENE18 GENE18 +GENE19 GENE19 +GENE20 GENE20 +GENE21 GENE21 +GENE22 GENE22 +GENE23 GENE23 +GENE24 GENE24 +GENE25 GENE25 +GENE26 GENE26 +GENE27 GENE27 +GENE28 GENE28 +GENE29 GENE29 +GENE30 GENE30 +GENE31 GENE31 +GENE32 GENE32 +GENE33 GENE33 +GENE34 GENE34 +GENE35 GENE35 +GENE36 GENE36 +GENE37 GENE37 +GENE38 GENE38 +GENE39 GENE39 +GENE40 GENE40 +GENE41 GENE41 +GENE42 GENE42 +GENE43 GENE43 +GENE44 GENE44 +GENE45 GENE45 +GENE46 GENE46 +GENE47 GENE47 +GENE48 GENE48 +GENE49 GENE49 +GENE50 GENE50 +GENE51 GENE51 +GENE52 GENE52 +GENE53 GENE53 +GENE54 GENE54 +GENE55 GENE55 +GENE56 GENE56 +GENE57 GENE57 +GENE58 GENE58 +GENE59 GENE59 +GENE60 GENE60 +GENE61 GENE61 +GENE62 GENE62 +GENE63 GENE63 +GENE64 GENE64 +GENE65 GENE65 +GENE66 GENE66 +GENE67 GENE67 +GENE68 GENE68 +GENE69 GENE69 +GENE70 GENE70 +GENE71 GENE71 +GENE72 GENE72 +GENE73 GENE73 +GENE74 GENE74 +GENE75 GENE75 +GENE76 GENE76 +GENE77 GENE77 +GENE78 GENE78 +GENE79 GENE79 +GENE80 GENE80 +GENE81 GENE81 +GENE82 GENE82 +GENE83 GENE83 +GENE84 GENE84 +GENE85 GENE85 +GENE86 GENE86 +GENE87 GENE87 +GENE88 GENE88 +GENE89 GENE89 +GENE90 GENE90 +GENE91 GENE91 +GENE92 GENE92 +GENE93 GENE93 +GENE94 GENE94 +GENE95 GENE95 +GENE96 GENE96 +GENE97 GENE97 +GENE98 GENE98 +GENE99 GENE99 +GENE100 GENE100
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/in_matrix.mtx Tue Jun 04 17:19:16 2019 -0400 @@ -0,0 +1,49364 @@ +%%MatrixMarket matrix coordinate integer general +100 11100 49362 +37 3 4 +85 3 4 +89 3 4 +43 10 3 +87 10 3 +29 17 3 +56 17 5 +82 17 3 +88 17 4 +95 17 4 +53 20 3 +67 20 3 +50 23 3 +84 23 3 +94 23 3 +66 27 3 +58 34 3 +67 34 3 +78 34 4 +85 34 3 +95 34 4 +100 34 4 +67 39 3 +78 39 4 +57 40 3 +64 40 3 +73 40 3 +90 40 4 +97 40 4 +27 45 3 +88 48 3 +47 52 3 +67 56 3 +92 56 4 +89 58 3 +64 62 3 +81 62 3 +99 62 3 +67 64 3 +49 69 3 +77 69 5 +99 69 4 +100 72 3 +69 75 3 +92 75 3 +73 76 3 +81 83 3 +90 84 3 +81 93 3 +94 93 3 +91 94 4 +100 94 3 +99 107 3 +56 112 3 +78 112 4 +90 112 5 +95 112 3 +77 120 3 +75 123 4 +91 148 3 +68 155 3 +90 155 4 +95 155 3 +42 156 3 +82 156 3 +95 158 3 +73 160 3 +63 162 4 +77 162 6 +79 162 3 +98 162 3 +74 163 3 +94 163 3 +63 164 5 +75 168 3 +58 172 3 +95 172 4 +49 180 3 +70 183 3 +97 188 3 +80 189 3 +98 189 3 +65 192 3 +28 200 3 +51 200 4 +57 200 3 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5 +44 11081 3 +47 11081 3 +55 11081 3 +62 11081 3 +67 11081 3 +71 11081 5 +77 11081 3 +91 11081 3 +100 11081 3 +7 11082 3 +14 11082 4 +24 11082 5 +32 11082 5 +35 11082 7 +42 11082 3 +44 11082 3 +59 11082 4 +62 11082 4 +68 11082 3 +74 11082 4 +77 11082 3 +83 11082 5 +87 11082 5 +91 11082 5 +100 11082 3 +13 11083 3 +21 11083 3 +42 11083 3 +75 11083 3 +94 11083 4 +7 11084 4 +9 11084 3 +20 11084 5 +24 11084 3 +32 11084 3 +34 11084 3 +39 11084 6 +43 11084 6 +48 11084 4 +62 11084 4 +64 11084 6 +74 11084 3 +79 11084 6 +84 11084 6 +91 11084 4 +100 11084 3 +7 11085 5 +16 11085 4 +22 11085 3 +34 11085 8 +39 11085 4 +43 11085 6 +47 11085 3 +55 11085 3 +65 11085 3 +76 11085 5 +79 11085 7 +84 11085 4 +97 11085 4 +7 11086 3 +29 11086 4 +32 11086 7 +39 11086 5 +43 11086 5 +45 11086 3 +62 11086 4 +67 11086 3 +74 11086 4 +78 11086 4 +86 11086 3 +91 11086 4 +95 11086 8 +6 11087 3 +11 11087 4 +16 11087 3 +24 11087 6 +29 11087 4 +36 11087 3 +40 11087 3 +44 11087 4 +48 11087 3 +64 11087 5 +73 11087 3 +76 11087 3 +79 11087 3 +86 11087 4 +89 11087 3 +91 11087 5 +2 11088 4 +20 11088 5 +28 11088 3 +32 11088 4 +43 11088 4 +48 11088 5 +54 11088 3 +64 11088 4 +67 11088 5 +72 11088 4 +76 11088 4 +79 11088 4 +84 11088 4 +90 11088 4 +100 11088 3 +12 11089 4 +21 11089 3 +28 11089 3 +34 11089 3 +43 11089 4 +47 11089 3 +70 11089 4 +79 11089 3 +1 11090 4 +6 11090 4 +15 11090 3 +20 11090 4 +34 11090 4 +38 11090 4 +40 11090 3 +45 11090 6 +47 11090 4 +61 11090 4 +64 11090 4 +73 11090 3 +76 11090 6 +78 11090 5 +83 11090 4 +86 11090 6 +91 11090 3 +96 11090 5 +100 11090 6 +11 11091 4 +13 11091 3 +25 11091 3 +32 11091 5 +36 11091 3 +41 11091 3 +43 11091 3 +47 11091 4 +63 11091 4 +76 11091 3 +78 11091 4 +83 11091 6 +90 11091 3 +96 11091 4 +5 11092 3 +16 11092 3 +22 11092 3 +28 11092 4 +34 11092 3 +38 11092 3 +41 11092 3 +43 11092 4 +46 11092 4 +48 11092 4 +63 11092 4 +74 11092 3 +78 11092 4 +83 11092 3 +87 11092 3 +91 11092 3 +5 11093 3 +15 11093 10 +18 11093 3 +20 11093 3 +24 11093 6 +31 11093 3 +33 11093 3 +35 11093 3 +43 11093 3 +48 11093 3 +74 11093 5 +83 11093 7 +86 11093 4 +90 11093 5 +95 11093 8 +8 11094 7 +11 11094 3 +16 11094 7 +20 11094 3 +23 11094 5 +27 11094 4 +29 11094 3 +34 11094 7 +36 11094 8 +42 11094 9 +44 11094 4 +46 11094 3 +48 11094 9 +51 11094 3 +54 11094 5 +59 11094 7 +63 11094 9 +67 11094 5 +71 11094 3 +74 11094 8 +76 11094 5 +78 11094 8 +81 11094 4 +83 11094 4 +86 11094 3 +88 11094 3 +91 11094 7 +100 11094 5 +6 11095 3 +9 11095 3 +12 11095 8 +15 11095 5 +23 11095 4 +28 11095 8 +31 11095 4 +33 11095 3 +36 11095 5 +42 11095 5 +45 11095 3 +50 11095 5 +59 11095 6 +62 11095 3 +64 11095 3 +67 11095 3 +70 11095 5 +74 11095 4 +78 11095 6 +83 11095 5 +86 11095 3 +92 11095 3 +95 11095 4 +100 11095 4 +9 11096 4 +16 11096 3 +26 11096 3 +28 11096 3 +32 11096 4 +44 11096 5 +70 11096 5 +79 11096 3 +87 11096 3 +94 11096 3 +16 11097 3 +22 11097 4 +29 11097 3 +34 11097 4 +38 11097 3 +44 11097 5 +59 11097 3 +70 11097 5 +74 11097 5 +78 11097 3 +87 11097 3 +93 11097 4 +100 11097 5 +9 11098 3 +15 11098 3 +20 11098 4 +27 11098 7 +34 11098 8 +46 11098 3 +51 11098 3 +62 11098 3 +70 11098 3 +74 11098 5 +77 11098 3 +82 11098 5 +84 11098 3 +91 11098 4 +7 11099 4 +12 11099 8 +24 11099 6 +28 11099 4 +32 11099 6 +42 11099 4 +45 11099 6 +59 11099 3 +63 11099 7 +66 11099 3 +74 11099 5 +77 11099 7 +81 11099 3 +84 11099 3 +91 11099 4 +100 11099 6 +11 11100 3 +16 11100 4 +25 11100 3 +32 11100 3 +34 11100 3 +36 11100 4 +39 11100 3 +43 11100 6 +47 11100 5 +55 11100 3 +63 11100 8 +70 11100 6 +74 11100 3 +78 11100 4 +82 11100 3 +84 11100 3 +91 11100 4 +95 11100 3
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/in_matrix.tsv Tue Jun 04 17:19:16 2019 -0400 @@ -0,0 +1,101 @@ + GGAAGAAGAA CGAAGAAGAA GCAAGAAGAA CCAAGAAGAA GAGAGAAGAA CAGAGAAGAA AGGAGAAGAA CGGAGAAGAA TGGAGAAGAA ACGAGAAGAA GCGAGAAGAA CCGAGAAGAA TCGAGAAGAA GTGAGAAGAA CTGAGAAGAA GACAGAAGAA CACAGAAGAA AGCAGAAGAA GGCAGAAGAA CGCAGAAGAA TGCAGAAGAA ACCAGAAGAA GCCAGAAGAA TCCAGAAGAA GTCAGAAGAA CTCAGAAGAA GGTAGAAGAA CGTAGAAGAA GCTAGAAGAA CCTAGAAGAA GAAGGAAGAA CAAGGAAGAA AGAGGAAGAA GGAGGAAGAA CGAGGAAGAA TGAGGAAGAA ACAGGAAGAA GCAGGAAGAA CCAGGAAGAA TCAGGAAGAA GTAGGAAGAA CTAGGAAGAA AACGGAAGAA GACGGAAGAA CACGGAAGAA TACGGAAGAA AGCGGAAGAA GGCGGAAGAA CGCGGAAGAA TGCGGAAGAA ACCGGAAGAA GCCGGAAGAA TCCGGAAGAA ATCGGAAGAA GTCGGAAGAA CTCGGAAGAA TTCGGAAGAA GATGGAAGAA CATGGAAGAA AGTGGAAGAA GGTGGAAGAA CGTGGAAGAA TGTGGAAGAA ACTGGAAGAA GCTGGAAGAA CCTGGAAGAA TCTGGAAGAA GTTGGAAGAA CTTGGAAGAA GAACGAAGAA CAACGAAGAA AGACGAAGAA GGACGAAGAA CGACGAAGAA TGACGAAGAA ACACGAAGAA GCACGAAGAA CCACGAAGAA TCACGAAGAA GTACGAAGAA CTACGAAGAA AAGCGAAGAA GAGCGAAGAA CAGCGAAGAA TAGCGAAGAA AGGCGAAGAA CGGCGAAGAA TGGCGAAGAA ACGCGAAGAA GCGCGAAGAA CCGCGAAGAA TCGCGAAGAA ATGCGAAGAA GTGCGAAGAA CTGCGAAGAA TTGCGAAGAA AACCGAAGAA GACCGAAGAA CACCGAAGAA TACCGAAGAA AGCCGAAGAA GGCCGAAGAA CGCCGAAGAA TGCCGAAGAA ATCCGAAGAA GTCCGAAGAA CTCCGAAGAA TTCCGAAGAA GATCGAAGAA CATCGAAGAA AGTCGAAGAA GGTCGAAGAA CGTCGAAGAA TGTCGAAGAA ACTCGAAGAA GCTCGAAGAA CCTCGAAGAA TCTCGAAGAA GTTCGAAGAA CTTCGAAGAA GGATGAAGAA CGATGAAGAA GCATGAAGAA CCATGAAGAA GAGTGAAGAA CAGTGAAGAA AGGTGAAGAA CGGTGAAGAA TGGTGAAGAA ACGTGAAGAA GCGTGAAGAA CCGTGAAGAA TCGTGAAGAA GTGTGAAGAA CTGTGAAGAA GACTGAAGAA CACTGAAGAA AGCTGAAGAA GGCTGAAGAA CGCTGAAGAA TGCTGAAGAA ACCTGAAGAA GCCTGAAGAA TCCTGAAGAA GTCTGAAGAA CTCTGAAGAA GGTTGAAGAA CGTTGAAGAA GCTTGAAGAA CCTTGAAGAA GGAACAAGAA CGAACAAGAA GCAACAAGAA CCAACAAGAA GAGACAAGAA CAGACAAGAA AGGACAAGAA CGGACAAGAA TGGACAAGAA ACGACAAGAA GCGACAAGAA CCGACAAGAA TCGACAAGAA GTGACAAGAA CTGACAAGAA GACACAAGAA CACACAAGAA AGCACAAGAA GGCACAAGAA CGCACAAGAA TGCACAAGAA ACCACAAGAA GCCACAAGAA TCCACAAGAA GTCACAAGAA CTCACAAGAA GGTACAAGAA CGTACAAGAA GCTACAAGAA CCTACAAGAA GAAGCAAGAA CAAGCAAGAA AGAGCAAGAA GGAGCAAGAA CGAGCAAGAA TGAGCAAGAA ACAGCAAGAA GCAGCAAGAA CCAGCAAGAA TCAGCAAGAA GTAGCAAGAA CTAGCAAGAA AAGGCAAGAA GAGGCAAGAA CAGGCAAGAA TAGGCAAGAA ACGGCAAGAA GCGGCAAGAA CCGGCAAGAA TCGGCAAGAA ATGGCAAGAA GTGGCAAGAA CTGGCAAGAA TTGGCAAGAA AACGCAAGAA GACGCAAGAA CACGCAAGAA TACGCAAGAA AGCGCAAGAA GGCGCAAGAA CGCGCAAGAA TGCGCAAGAA ACCGCAAGAA GCCGCAAGAA TCCGCAAGAA ATCGCAAGAA GTCGCAAGAA CTCGCAAGAA TTCGCAAGAA GATGCAAGAA CATGCAAGAA AGTGCAAGAA GGTGCAAGAA CGTGCAAGAA TGTGCAAGAA ACTGCAAGAA GCTGCAAGAA CCTGCAAGAA TCTGCAAGAA GTTGCAAGAA CTTGCAAGAA GAACCAAGAA CAACCAAGAA AGACCAAGAA GGACCAAGAA CGACCAAGAA TGACCAAGAA ACACCAAGAA GCACCAAGAA CCACCAAGAA TCACCAAGAA GTACCAAGAA CTACCAAGAA AAGCCAAGAA GAGCCAAGAA CAGCCAAGAA TAGCCAAGAA AGGCCAAGAA CGGCCAAGAA TGGCCAAGAA ACGCCAAGAA GCGCCAAGAA CCGCCAAGAA TCGCCAAGAA ATGCCAAGAA GTGCCAAGAA CTGCCAAGAA TTGCCAAGAA GATCCAAGAA CATCCAAGAA AGTCCAAGAA GGTCCAAGAA CGTCCAAGAA TGTCCAAGAA ACTCCAAGAA GCTCCAAGAA CCTCCAAGAA TCTCCAAGAA GTTCCAAGAA CTTCCAAGAA GGATCAAGAA CGATCAAGAA GCATCAAGAA CCATCAAGAA GAGTCAAGAA CAGTCAAGAA AGGTCAAGAA CGGTCAAGAA TGGTCAAGAA ACGTCAAGAA GCGTCAAGAA CCGTCAAGAA TCGTCAAGAA GTGTCAAGAA CTGTCAAGAA GACTCAAGAA CACTCAAGAA AGCTCAAGAA GGCTCAAGAA CGCTCAAGAA TGCTCAAGAA ACCTCAAGAA GCCTCAAGAA TCCTCAAGAA GTCTCAAGAA CTCTCAAGAA GGTTCAAGAA CGTTCAAGAA GCTTCAAGAA CCTTCAAGAA CGGATAAGAA GCGATAAGAA CCGATAAGAA GGCATAAGAA CGCATAAGAA GCCATAAGAA GGAGTAAGAA CGAGTAAGAA GCAGTAAGAA CCAGTAAGAA GAGGTAAGAA CAGGTAAGAA ACGGTAAGAA GCGGTAAGAA CCGGTAAGAA TCGGTAAGAA GTGGTAAGAA CTGGTAAGAA GACGTAAGAA CACGTAAGAA AGCGTAAGAA GGCGTAAGAA CGCGTAAGAA TGCGTAAGAA ACCGTAAGAA GCCGTAAGAA TCCGTAAGAA GTCGTAAGAA CTCGTAAGAA GGTGTAAGAA CGTGTAAGAA GCTGTAAGAA CCTGTAAGAA GGACTAAGAA CGACTAAGAA GCACTAAGAA CCACTAAGAA GAGCTAAGAA CAGCTAAGAA AGGCTAAGAA CGGCTAAGAA TGGCTAAGAA ACGCTAAGAA GCGCTAAGAA CCGCTAAGAA TCGCTAAGAA GTGCTAAGAA CTGCTAAGAA GACCTAAGAA CACCTAAGAA AGCCTAAGAA GGCCTAAGAA CGCCTAAGAA TGCCTAAGAA GTCCTAAGAA CTCCTAAGAA GGTCTAAGAA CGTCTAAGAA GCTCTAAGAA CCTCTAAGAA CGGTTAAGAA GCGTTAAGAA CCGTTAAGAA GGCTTAAGAA CGCTTAAGAA GCCTTAAGAA GAGAAGAGAA CAGAAGAGAA AGGAAGAGAA CGGAAGAGAA TGGAAGAGAA ACGAAGAGAA GCGAAGAGAA CCGAAGAGAA TCGAAGAGAA GTGAAGAGAA CTGAAGAGAA GACAAGAGAA CACAAGAGAA AGCAAGAGAA GGCAAGAGAA CGCAAGAGAA TGCAAGAGAA ACCAAGAGAA GCCAAGAGAA TCCAAGAGAA GTCAAGAGAA CTCAAGAGAA GGTAAGAGAA CGTAAGAGAA GCTAAGAGAA CCTAAGAGAA GAAGAGAGAA CAAGAGAGAA AGAGAGAGAA GGAGAGAGAA CGAGAGAGAA TGAGAGAGAA ACAGAGAGAA GCAGAGAGAA CCAGAGAGAA TCAGAGAGAA GTAGAGAGAA CTAGAGAGAA AAGGAGAGAA GAGGAGAGAA CAGGAGAGAA TAGGAGAGAA ACGGAGAGAA GCGGAGAGAA CCGGAGAGAA TCGGAGAGAA ATGGAGAGAA GTGGAGAGAA CTGGAGAGAA TTGGAGAGAA AACGAGAGAA GACGAGAGAA CACGAGAGAA TACGAGAGAA AGCGAGAGAA GGCGAGAGAA CGCGAGAGAA TGCGAGAGAA ACCGAGAGAA GCCGAGAGAA TCCGAGAGAA ATCGAGAGAA GTCGAGAGAA CTCGAGAGAA TTCGAGAGAA GATGAGAGAA CATGAGAGAA AGTGAGAGAA GGTGAGAGAA CGTGAGAGAA TGTGAGAGAA ACTGAGAGAA GCTGAGAGAA CCTGAGAGAA TCTGAGAGAA GTTGAGAGAA CTTGAGAGAA GAACAGAGAA CAACAGAGAA AGACAGAGAA GGACAGAGAA CGACAGAGAA TGACAGAGAA ACACAGAGAA GCACAGAGAA CCACAGAGAA TCACAGAGAA GTACAGAGAA CTACAGAGAA AAGCAGAGAA GAGCAGAGAA CAGCAGAGAA TAGCAGAGAA AGGCAGAGAA CGGCAGAGAA TGGCAGAGAA ACGCAGAGAA GCGCAGAGAA CCGCAGAGAA TCGCAGAGAA ATGCAGAGAA GTGCAGAGAA CTGCAGAGAA TTGCAGAGAA AACCAGAGAA GACCAGAGAA CACCAGAGAA TACCAGAGAA AGCCAGAGAA GGCCAGAGAA CGCCAGAGAA TGCCAGAGAA ATCCAGAGAA GTCCAGAGAA CTCCAGAGAA TTCCAGAGAA GATCAGAGAA CATCAGAGAA AGTCAGAGAA GGTCAGAGAA CGTCAGAGAA TGTCAGAGAA ACTCAGAGAA GCTCAGAGAA CCTCAGAGAA TCTCAGAGAA GTTCAGAGAA CTTCAGAGAA GGATAGAGAA CGATAGAGAA GCATAGAGAA CCATAGAGAA GAGTAGAGAA CAGTAGAGAA AGGTAGAGAA CGGTAGAGAA TGGTAGAGAA ACGTAGAGAA GCGTAGAGAA CCGTAGAGAA TCGTAGAGAA GTGTAGAGAA CTGTAGAGAA GACTAGAGAA CACTAGAGAA AGCTAGAGAA GGCTAGAGAA CGCTAGAGAA TGCTAGAGAA ACCTAGAGAA GCCTAGAGAA TCCTAGAGAA GTCTAGAGAA CTCTAGAGAA GGTTAGAGAA CGTTAGAGAA GCTTAGAGAA CCTTAGAGAA AGAAGGAGAA GGAAGGAGAA CGAAGGAGAA TGAAGGAGAA ACAAGGAGAA GCAAGGAGAA CCAAGGAGAA TCAAGGAGAA GTAAGGAGAA CTAAGGAGAA AAGAGGAGAA GAGAGGAGAA CAGAGGAGAA TAGAGGAGAA AGGAGGAGAA CGGAGGAGAA TGGAGGAGAA ACGAGGAGAA GCGAGGAGAA CCGAGGAGAA TCGAGGAGAA ATGAGGAGAA GTGAGGAGAA CTGAGGAGAA TTGAGGAGAA AACAGGAGAA GACAGGAGAA CACAGGAGAA TACAGGAGAA AGCAGGAGAA GGCAGGAGAA CGCAGGAGAA TGCAGGAGAA ACCAGGAGAA GCCAGGAGAA TCCAGGAGAA ATCAGGAGAA GTCAGGAGAA CTCAGGAGAA TTCAGGAGAA GATAGGAGAA CATAGGAGAA AGTAGGAGAA GGTAGGAGAA CGTAGGAGAA TGTAGGAGAA ACTAGGAGAA GCTAGGAGAA CCTAGGAGAA TCTAGGAGAA GTTAGGAGAA CTTAGGAGAA GAACGGAGAA CAACGGAGAA TAACGGAGAA AGACGGAGAA GGACGGAGAA CGACGGAGAA TGACGGAGAA ACACGGAGAA GCACGGAGAA CCACGGAGAA TCACGGAGAA ATACGGAGAA GTACGGAGAA CTACGGAGAA TTACGGAGAA AAGCGGAGAA GAGCGGAGAA CAGCGGAGAA TAGCGGAGAA AGGCGGAGAA TGGCGGAGAA ACGCGGAGAA TCGCGGAGAA ATGCGGAGAA GTGCGGAGAA CTGCGGAGAA TTGCGGAGAA AACCGGAGAA GACCGGAGAA CACCGGAGAA TACCGGAGAA AGCCGGAGAA TGCCGGAGAA ATCCGGAGAA GTCCGGAGAA CTCCGGAGAA TTCCGGAGAA AATCGGAGAA GATCGGAGAA CATCGGAGAA TATCGGAGAA AGTCGGAGAA GGTCGGAGAA CGTCGGAGAA TGTCGGAGAA ACTCGGAGAA GCTCGGAGAA CCTCGGAGAA TCTCGGAGAA ATTCGGAGAA GTTCGGAGAA CTTCGGAGAA GAATGGAGAA CAATGGAGAA AGATGGAGAA GGATGGAGAA CGATGGAGAA TGATGGAGAA ACATGGAGAA GCATGGAGAA CCATGGAGAA TCATGGAGAA GTATGGAGAA CTATGGAGAA AAGTGGAGAA GAGTGGAGAA CAGTGGAGAA TAGTGGAGAA AGGTGGAGAA CGGTGGAGAA TGGTGGAGAA ACGTGGAGAA GCGTGGAGAA CCGTGGAGAA TCGTGGAGAA ATGTGGAGAA GTGTGGAGAA CTGTGGAGAA TTGTGGAGAA AACTGGAGAA GACTGGAGAA CACTGGAGAA TACTGGAGAA AGCTGGAGAA GGCTGGAGAA CGCTGGAGAA TGCTGGAGAA ACCTGGAGAA GCCTGGAGAA TCCTGGAGAA ATCTGGAGAA GTCTGGAGAA CTCTGGAGAA TTCTGGAGAA GATTGGAGAA CATTGGAGAA AGTTGGAGAA GGTTGGAGAA CGTTGGAGAA TGTTGGAGAA ACTTGGAGAA GCTTGGAGAA CCTTGGAGAA TCTTGGAGAA AGAACGAGAA GGAACGAGAA CGAACGAGAA TGAACGAGAA ACAACGAGAA GCAACGAGAA CCAACGAGAA TCAACGAGAA GTAACGAGAA CTAACGAGAA AAGACGAGAA GAGACGAGAA CAGACGAGAA TAGACGAGAA AGGACGAGAA CGGACGAGAA TGGACGAGAA ACGACGAGAA GCGACGAGAA CCGACGAGAA TCGACGAGAA ATGACGAGAA GTGACGAGAA CTGACGAGAA TTGACGAGAA AACACGAGAA GACACGAGAA CACACGAGAA TACACGAGAA AGCACGAGAA GGCACGAGAA CGCACGAGAA TGCACGAGAA ACCACGAGAA GCCACGAGAA TCCACGAGAA ATCACGAGAA GTCACGAGAA CTCACGAGAA TTCACGAGAA GATACGAGAA CATACGAGAA AGTACGAGAA GGTACGAGAA CGTACGAGAA TGTACGAGAA ACTACGAGAA GCTACGAGAA CCTACGAGAA TCTACGAGAA GTTACGAGAA CTTACGAGAA GAAGCGAGAA CAAGCGAGAA TAAGCGAGAA AGAGCGAGAA GGAGCGAGAA CGAGCGAGAA TGAGCGAGAA ACAGCGAGAA GCAGCGAGAA CCAGCGAGAA TCAGCGAGAA ATAGCGAGAA GTAGCGAGAA CTAGCGAGAA TTAGCGAGAA AAGGCGAGAA GAGGCGAGAA CAGGCGAGAA TAGGCGAGAA ACGGCGAGAA TCGGCGAGAA ATGGCGAGAA GTGGCGAGAA CTGGCGAGAA TTGGCGAGAA AACGCGAGAA GACGCGAGAA CACGCGAGAA TACGCGAGAA AGCGCGAGAA TGCGCGAGAA ACCGCGAGAA TCCGCGAGAA ATCGCGAGAA GTCGCGAGAA CTCGCGAGAA TTCGCGAGAA AATGCGAGAA GATGCGAGAA CATGCGAGAA TATGCGAGAA AGTGCGAGAA GGTGCGAGAA CGTGCGAGAA TGTGCGAGAA ACTGCGAGAA GCTGCGAGAA CCTGCGAGAA TCTGCGAGAA ATTGCGAGAA GTTGCGAGAA CTTGCGAGAA GAACCGAGAA CAACCGAGAA TAACCGAGAA AGACCGAGAA GGACCGAGAA CGACCGAGAA TGACCGAGAA ACACCGAGAA GCACCGAGAA CCACCGAGAA TCACCGAGAA ATACCGAGAA GTACCGAGAA CTACCGAGAA TTACCGAGAA AAGCCGAGAA GAGCCGAGAA CAGCCGAGAA TAGCCGAGAA AGGCCGAGAA TGGCCGAGAA ACGCCGAGAA TCGCCGAGAA ATGCCGAGAA GTGCCGAGAA CTGCCGAGAA TTGCCGAGAA AATCCGAGAA GATCCGAGAA CATCCGAGAA TATCCGAGAA AGTCCGAGAA GGTCCGAGAA CGTCCGAGAA TGTCCGAGAA ACTCCGAGAA GCTCCGAGAA CCTCCGAGAA TCTCCGAGAA ATTCCGAGAA GTTCCGAGAA CTTCCGAGAA GAATCGAGAA CAATCGAGAA AGATCGAGAA GGATCGAGAA CGATCGAGAA TGATCGAGAA ACATCGAGAA GCATCGAGAA CCATCGAGAA TCATCGAGAA GTATCGAGAA CTATCGAGAA AAGTCGAGAA GAGTCGAGAA CAGTCGAGAA TAGTCGAGAA AGGTCGAGAA CGGTCGAGAA TGGTCGAGAA ACGTCGAGAA GCGTCGAGAA CCGTCGAGAA TCGTCGAGAA ATGTCGAGAA GTGTCGAGAA CTGTCGAGAA TTGTCGAGAA AACTCGAGAA GACTCGAGAA CACTCGAGAA TACTCGAGAA AGCTCGAGAA GGCTCGAGAA CGCTCGAGAA TGCTCGAGAA ACCTCGAGAA GCCTCGAGAA TCCTCGAGAA ATCTCGAGAA GTCTCGAGAA CTCTCGAGAA GATTCGAGAA CATTCGAGAA AGTTCGAGAA GGTTCGAGAA CGTTCGAGAA TGTTCGAGAA ACTTCGAGAA GCTTCGAGAA CCTTCGAGAA TCTTCGAGAA GGAATGAGAA CGAATGAGAA GCAATGAGAA CCAATGAGAA GAGATGAGAA CAGATGAGAA AGGATGAGAA CGGATGAGAA TGGATGAGAA ACGATGAGAA GCGATGAGAA CCGATGAGAA TCGATGAGAA GTGATGAGAA CTGATGAGAA GACATGAGAA CACATGAGAA AGCATGAGAA GGCATGAGAA CGCATGAGAA TGCATGAGAA ACCATGAGAA GCCATGAGAA TCCATGAGAA GTCATGAGAA CTCATGAGAA GGTATGAGAA CGTATGAGAA GCTATGAGAA CCTATGAGAA GAAGTGAGAA CAAGTGAGAA AGAGTGAGAA GGAGTGAGAA CGAGTGAGAA TGAGTGAGAA ACAGTGAGAA GCAGTGAGAA CCAGTGAGAA TCAGTGAGAA GTAGTGAGAA CTAGTGAGAA AAGGTGAGAA GAGGTGAGAA CAGGTGAGAA TAGGTGAGAA ACGGTGAGAA GCGGTGAGAA CCGGTGAGAA TCGGTGAGAA ATGGTGAGAA GTGGTGAGAA CTGGTGAGAA TTGGTGAGAA AACGTGAGAA GACGTGAGAA CACGTGAGAA TACGTGAGAA AGCGTGAGAA GGCGTGAGAA CGCGTGAGAA TGCGTGAGAA ACCGTGAGAA GCCGTGAGAA TCCGTGAGAA ATCGTGAGAA GTCGTGAGAA CTCGTGAGAA TTCGTGAGAA GATGTGAGAA CATGTGAGAA AGTGTGAGAA GGTGTGAGAA CGTGTGAGAA TGTGTGAGAA ACTGTGAGAA GCTGTGAGAA CCTGTGAGAA TCTGTGAGAA GTTGTGAGAA CTTGTGAGAA GAACTGAGAA CAACTGAGAA AGACTGAGAA GGACTGAGAA CGACTGAGAA TGACTGAGAA ACACTGAGAA GCACTGAGAA CCACTGAGAA TCACTGAGAA GTACTGAGAA CTACTGAGAA AAGCTGAGAA GAGCTGAGAA CAGCTGAGAA TAGCTGAGAA AGGCTGAGAA CGGCTGAGAA TGGCTGAGAA ACGCTGAGAA GCGCTGAGAA CCGCTGAGAA TCGCTGAGAA ATGCTGAGAA GTGCTGAGAA CTGCTGAGAA TTGCTGAGAA AACCTGAGAA GACCTGAGAA CACCTGAGAA TACCTGAGAA AGCCTGAGAA GGCCTGAGAA CGCCTGAGAA TGCCTGAGAA ATCCTGAGAA GTCCTGAGAA CTCCTGAGAA TTCCTGAGAA GATCTGAGAA CATCTGAGAA AGTCTGAGAA GGTCTGAGAA CGTCTGAGAA TGTCTGAGAA ACTCTGAGAA GCTCTGAGAA CCTCTGAGAA TCTCTGAGAA GTTCTGAGAA CTTCTGAGAA GGATTGAGAA CGATTGAGAA GCATTGAGAA CCATTGAGAA GAGTTGAGAA CAGTTGAGAA AGGTTGAGAA CGGTTGAGAA TGGTTGAGAA ACGTTGAGAA GCGTTGAGAA CCGTTGAGAA TCGTTGAGAA GTGTTGAGAA CTGTTGAGAA GACTTGAGAA CACTTGAGAA AGCTTGAGAA GGCTTGAGAA CGCTTGAGAA TGCTTGAGAA ACCTTGAGAA GCCTTGAGAA TCCTTGAGAA GTCTTGAGAA CTCTTGAGAA GAGAACAGAA CAGAACAGAA AGGAACAGAA CGGAACAGAA TGGAACAGAA ACGAACAGAA GCGAACAGAA CCGAACAGAA TCGAACAGAA GTGAACAGAA CTGAACAGAA GACAACAGAA CACAACAGAA AGCAACAGAA GGCAACAGAA CGCAACAGAA TGCAACAGAA ACCAACAGAA GCCAACAGAA TCCAACAGAA GTCAACAGAA CTCAACAGAA GGTAACAGAA CGTAACAGAA GCTAACAGAA CCTAACAGAA GAAGACAGAA CAAGACAGAA AGAGACAGAA GGAGACAGAA CGAGACAGAA TGAGACAGAA ACAGACAGAA GCAGACAGAA CCAGACAGAA TCAGACAGAA GTAGACAGAA CTAGACAGAA AAGGACAGAA GAGGACAGAA CAGGACAGAA TAGGACAGAA ACGGACAGAA GCGGACAGAA CCGGACAGAA TCGGACAGAA ATGGACAGAA GTGGACAGAA CTGGACAGAA TTGGACAGAA AACGACAGAA GACGACAGAA CACGACAGAA TACGACAGAA AGCGACAGAA GGCGACAGAA CGCGACAGAA TGCGACAGAA ACCGACAGAA GCCGACAGAA TCCGACAGAA ATCGACAGAA GTCGACAGAA CTCGACAGAA TTCGACAGAA GATGACAGAA CATGACAGAA AGTGACAGAA GGTGACAGAA CGTGACAGAA TGTGACAGAA ACTGACAGAA GCTGACAGAA CCTGACAGAA TCTGACAGAA GTTGACAGAA CTTGACAGAA GAACACAGAA CAACACAGAA AGACACAGAA GGACACAGAA CGACACAGAA TGACACAGAA ACACACAGAA GCACACAGAA CCACACAGAA TCACACAGAA GTACACAGAA CTACACAGAA AAGCACAGAA GAGCACAGAA CAGCACAGAA TAGCACAGAA AGGCACAGAA CGGCACAGAA TGGCACAGAA ACGCACAGAA GCGCACAGAA CCGCACAGAA TCGCACAGAA ATGCACAGAA GTGCACAGAA CTGCACAGAA TTGCACAGAA AACCACAGAA GACCACAGAA CACCACAGAA TACCACAGAA AGCCACAGAA GGCCACAGAA CGCCACAGAA TGCCACAGAA ATCCACAGAA GTCCACAGAA CTCCACAGAA TTCCACAGAA GATCACAGAA CATCACAGAA AGTCACAGAA GGTCACAGAA CGTCACAGAA TGTCACAGAA ACTCACAGAA GCTCACAGAA CCTCACAGAA TCTCACAGAA GTTCACAGAA CTTCACAGAA GGATACAGAA CGATACAGAA GCATACAGAA CCATACAGAA GAGTACAGAA CAGTACAGAA AGGTACAGAA CGGTACAGAA TGGTACAGAA ACGTACAGAA GCGTACAGAA CCGTACAGAA TCGTACAGAA GTGTACAGAA CTGTACAGAA GACTACAGAA CACTACAGAA AGCTACAGAA GGCTACAGAA CGCTACAGAA TGCTACAGAA ACCTACAGAA GCCTACAGAA TCCTACAGAA GTCTACAGAA CTCTACAGAA GGTTACAGAA CGTTACAGAA GCTTACAGAA CCTTACAGAA AGAAGCAGAA GGAAGCAGAA CGAAGCAGAA TGAAGCAGAA ACAAGCAGAA GCAAGCAGAA CCAAGCAGAA TCAAGCAGAA GTAAGCAGAA CTAAGCAGAA AAGAGCAGAA GAGAGCAGAA CAGAGCAGAA TAGAGCAGAA AGGAGCAGAA CGGAGCAGAA TGGAGCAGAA ACGAGCAGAA GCGAGCAGAA CCGAGCAGAA TCGAGCAGAA ATGAGCAGAA GTGAGCAGAA CTGAGCAGAA TTGAGCAGAA AACAGCAGAA GACAGCAGAA CACAGCAGAA TACAGCAGAA AGCAGCAGAA GGCAGCAGAA CGCAGCAGAA TGCAGCAGAA ACCAGCAGAA GCCAGCAGAA TCCAGCAGAA ATCAGCAGAA GTCAGCAGAA CTCAGCAGAA TTCAGCAGAA GATAGCAGAA CATAGCAGAA AGTAGCAGAA GGTAGCAGAA CGTAGCAGAA TGTAGCAGAA ACTAGCAGAA GCTAGCAGAA CCTAGCAGAA TCTAGCAGAA GTTAGCAGAA CTTAGCAGAA GAAGGCAGAA CAAGGCAGAA TAAGGCAGAA AGAGGCAGAA GGAGGCAGAA CGAGGCAGAA TGAGGCAGAA ACAGGCAGAA GCAGGCAGAA CCAGGCAGAA TCAGGCAGAA ATAGGCAGAA GTAGGCAGAA CTAGGCAGAA TTAGGCAGAA AACGGCAGAA GACGGCAGAA CACGGCAGAA TACGGCAGAA AGCGGCAGAA TGCGGCAGAA ACCGGCAGAA TCCGGCAGAA ATCGGCAGAA GTCGGCAGAA CTCGGCAGAA TTCGGCAGAA AATGGCAGAA GATGGCAGAA CATGGCAGAA TATGGCAGAA AGTGGCAGAA GGTGGCAGAA CGTGGCAGAA TGTGGCAGAA ACTGGCAGAA GCTGGCAGAA CCTGGCAGAA TCTGGCAGAA ATTGGCAGAA GTTGGCAGAA CTTGGCAGAA GAACGCAGAA CAACGCAGAA TAACGCAGAA AGACGCAGAA GGACGCAGAA CGACGCAGAA TGACGCAGAA ACACGCAGAA GCACGCAGAA CCACGCAGAA TCACGCAGAA ATACGCAGAA GTACGCAGAA CTACGCAGAA TTACGCAGAA AAGCGCAGAA GAGCGCAGAA CAGCGCAGAA TAGCGCAGAA AGGCGCAGAA TGGCGCAGAA ACGCGCAGAA TCGCGCAGAA ATGCGCAGAA GTGCGCAGAA CTGCGCAGAA TTGCGCAGAA AACCGCAGAA GACCGCAGAA CACCGCAGAA TACCGCAGAA AGCCGCAGAA TGCCGCAGAA ATCCGCAGAA GTCCGCAGAA CTCCGCAGAA TTCCGCAGAA AATCGCAGAA GATCGCAGAA CATCGCAGAA TATCGCAGAA AGTCGCAGAA GGTCGCAGAA CGTCGCAGAA TGTCGCAGAA ACTCGCAGAA GCTCGCAGAA CCTCGCAGAA TCTCGCAGAA ATTCGCAGAA GTTCGCAGAA CTTCGCAGAA GAATGCAGAA CAATGCAGAA AGATGCAGAA GGATGCAGAA CGATGCAGAA TGATGCAGAA ACATGCAGAA GCATGCAGAA CCATGCAGAA TCATGCAGAA GTATGCAGAA CTATGCAGAA AAGTGCAGAA GAGTGCAGAA CAGTGCAGAA TAGTGCAGAA AGGTGCAGAA CGGTGCAGAA TGGTGCAGAA ACGTGCAGAA GCGTGCAGAA CCGTGCAGAA TCGTGCAGAA ATGTGCAGAA GTGTGCAGAA CTGTGCAGAA TTGTGCAGAA AACTGCAGAA GACTGCAGAA CACTGCAGAA TACTGCAGAA AGCTGCAGAA GGCTGCAGAA CGCTGCAGAA TGCTGCAGAA ACCTGCAGAA GCCTGCAGAA TCCTGCAGAA ATCTGCAGAA GTCTGCAGAA CTCTGCAGAA GATTGCAGAA CATTGCAGAA AGTTGCAGAA GGTTGCAGAA CGTTGCAGAA TGTTGCAGAA ACTTGCAGAA GCTTGCAGAA CCTTGCAGAA TCTTGCAGAA AGAACCAGAA GGAACCAGAA CGAACCAGAA TGAACCAGAA ACAACCAGAA GCAACCAGAA CCAACCAGAA TCAACCAGAA GTAACCAGAA CTAACCAGAA AAGACCAGAA GAGACCAGAA CAGACCAGAA TAGACCAGAA AGGACCAGAA CGGACCAGAA TGGACCAGAA ACGACCAGAA GCGACCAGAA CCGACCAGAA TCGACCAGAA ATGACCAGAA GTGACCAGAA CTGACCAGAA TTGACCAGAA AACACCAGAA GACACCAGAA CACACCAGAA TACACCAGAA AGCACCAGAA GGCACCAGAA CGCACCAGAA TGCACCAGAA ACCACCAGAA GCCACCAGAA TCCACCAGAA ATCACCAGAA GTCACCAGAA CTCACCAGAA TTCACCAGAA GATACCAGAA CATACCAGAA AGTACCAGAA GGTACCAGAA CGTACCAGAA TGTACCAGAA ACTACCAGAA GCTACCAGAA CCTACCAGAA TCTACCAGAA GTTACCAGAA CTTACCAGAA GAAGCCAGAA CAAGCCAGAA TAAGCCAGAA AGAGCCAGAA GGAGCCAGAA CGAGCCAGAA TGAGCCAGAA ACAGCCAGAA GCAGCCAGAA CCAGCCAGAA TCAGCCAGAA ATAGCCAGAA GTAGCCAGAA CTAGCCAGAA TTAGCCAGAA AAGGCCAGAA GAGGCCAGAA CAGGCCAGAA TAGGCCAGAA ACGGCCAGAA TCGGCCAGAA ATGGCCAGAA GTGGCCAGAA CTGGCCAGAA TTGGCCAGAA AACGCCAGAA GACGCCAGAA CACGCCAGAA TACGCCAGAA AGCGCCAGAA TGCGCCAGAA ACCGCCAGAA TCCGCCAGAA ATCGCCAGAA GTCGCCAGAA CTCGCCAGAA TTCGCCAGAA AATGCCAGAA GATGCCAGAA CATGCCAGAA TATGCCAGAA AGTGCCAGAA GGTGCCAGAA CGTGCCAGAA TGTGCCAGAA ACTGCCAGAA GCTGCCAGAA CCTGCCAGAA TCTGCCAGAA ATTGCCAGAA GTTGCCAGAA CTTGCCAGAA GAATCCAGAA CAATCCAGAA AGATCCAGAA GGATCCAGAA CGATCCAGAA TGATCCAGAA ACATCCAGAA GCATCCAGAA CCATCCAGAA TCATCCAGAA GTATCCAGAA CTATCCAGAA AAGTCCAGAA GAGTCCAGAA CAGTCCAGAA TAGTCCAGAA AGGTCCAGAA CGGTCCAGAA TGGTCCAGAA ACGTCCAGAA GCGTCCAGAA CCGTCCAGAA TCGTCCAGAA ATGTCCAGAA GTGTCCAGAA CTGTCCAGAA TTGTCCAGAA AACTCCAGAA GACTCCAGAA CACTCCAGAA TACTCCAGAA AGCTCCAGAA GGCTCCAGAA CGCTCCAGAA TGCTCCAGAA ACCTCCAGAA GCCTCCAGAA TCCTCCAGAA ATCTCCAGAA GTCTCCAGAA CTCTCCAGAA TTCTCCAGAA GATTCCAGAA CATTCCAGAA AGTTCCAGAA GGTTCCAGAA CGTTCCAGAA TGTTCCAGAA ACTTCCAGAA GCTTCCAGAA CCTTCCAGAA TCTTCCAGAA GGAATCAGAA CGAATCAGAA GCAATCAGAA CCAATCAGAA GAGATCAGAA CAGATCAGAA AGGATCAGAA CGGATCAGAA TGGATCAGAA ACGATCAGAA GCGATCAGAA CCGATCAGAA TCGATCAGAA GTGATCAGAA CTGATCAGAA GACATCAGAA CACATCAGAA AGCATCAGAA GGCATCAGAA CGCATCAGAA TGCATCAGAA ACCATCAGAA GCCATCAGAA TCCATCAGAA GTCATCAGAA CTCATCAGAA GGTATCAGAA CGTATCAGAA GCTATCAGAA CCTATCAGAA GAAGTCAGAA CAAGTCAGAA AGAGTCAGAA GGAGTCAGAA CGAGTCAGAA TGAGTCAGAA ACAGTCAGAA GCAGTCAGAA CCAGTCAGAA TCAGTCAGAA GTAGTCAGAA CTAGTCAGAA AAGGTCAGAA GAGGTCAGAA CAGGTCAGAA TAGGTCAGAA ACGGTCAGAA GCGGTCAGAA CCGGTCAGAA TCGGTCAGAA ATGGTCAGAA GTGGTCAGAA CTGGTCAGAA TTGGTCAGAA AACGTCAGAA GACGTCAGAA CACGTCAGAA TACGTCAGAA AGCGTCAGAA GGCGTCAGAA CGCGTCAGAA TGCGTCAGAA ACCGTCAGAA GCCGTCAGAA TCCGTCAGAA ATCGTCAGAA GTCGTCAGAA CTCGTCAGAA TTCGTCAGAA GATGTCAGAA CATGTCAGAA AGTGTCAGAA GGTGTCAGAA CGTGTCAGAA TGTGTCAGAA ACTGTCAGAA GCTGTCAGAA CCTGTCAGAA TCTGTCAGAA GTTGTCAGAA CTTGTCAGAA GAACTCAGAA CAACTCAGAA AGACTCAGAA GGACTCAGAA CGACTCAGAA TGACTCAGAA ACACTCAGAA GCACTCAGAA CCACTCAGAA TCACTCAGAA GTACTCAGAA CTACTCAGAA AAGCTCAGAA GAGCTCAGAA CAGCTCAGAA TAGCTCAGAA AGGCTCAGAA CGGCTCAGAA TGGCTCAGAA ACGCTCAGAA GCGCTCAGAA CCGCTCAGAA TCGCTCAGAA ATGCTCAGAA GTGCTCAGAA CTGCTCAGAA TTGCTCAGAA AACCTCAGAA GACCTCAGAA CACCTCAGAA TACCTCAGAA AGCCTCAGAA GGCCTCAGAA CGCCTCAGAA TGCCTCAGAA ATCCTCAGAA GTCCTCAGAA CTCCTCAGAA TTCCTCAGAA GATCTCAGAA CATCTCAGAA AGTCTCAGAA GGTCTCAGAA CGTCTCAGAA TGTCTCAGAA ACTCTCAGAA GCTCTCAGAA CCTCTCAGAA TCTCTCAGAA GTTCTCAGAA CTTCTCAGAA GGATTCAGAA CGATTCAGAA GCATTCAGAA CCATTCAGAA GAGTTCAGAA CAGTTCAGAA AGGTTCAGAA CGGTTCAGAA TGGTTCAGAA ACGTTCAGAA GCGTTCAGAA CCGTTCAGAA TCGTTCAGAA GTGTTCAGAA CTGTTCAGAA GACTTCAGAA CACTTCAGAA AGCTTCAGAA GGCTTCAGAA CGCTTCAGAA TGCTTCAGAA ACCTTCAGAA GCCTTCAGAA TCCTTCAGAA GTCTTCAGAA CTCTTCAGAA CGGAATAGAA GCGAATAGAA CCGAATAGAA GGCAATAGAA CGCAATAGAA GCCAATAGAA GGAGATAGAA CGAGATAGAA GCAGATAGAA CCAGATAGAA GAGGATAGAA CAGGATAGAA ACGGATAGAA GCGGATAGAA CCGGATAGAA TCGGATAGAA GTGGATAGAA CTGGATAGAA GACGATAGAA CACGATAGAA AGCGATAGAA GGCGATAGAA CGCGATAGAA TGCGATAGAA ACCGATAGAA GCCGATAGAA TCCGATAGAA GTCGATAGAA CTCGATAGAA GGTGATAGAA CGTGATAGAA GCTGATAGAA CCTGATAGAA GGACATAGAA CGACATAGAA GCACATAGAA CCACATAGAA GAGCATAGAA CAGCATAGAA AGGCATAGAA CGGCATAGAA TGGCATAGAA ACGCATAGAA GCGCATAGAA CCGCATAGAA TCGCATAGAA GTGCATAGAA CTGCATAGAA GACCATAGAA CACCATAGAA AGCCATAGAA GGCCATAGAA CGCCATAGAA TGCCATAGAA GTCCATAGAA CTCCATAGAA GGTCATAGAA CGTCATAGAA GCTCATAGAA CCTCATAGAA CGGTATAGAA GCGTATAGAA CCGTATAGAA GGCTATAGAA CGCTATAGAA GCCTATAGAA GGAAGTAGAA CGAAGTAGAA GCAAGTAGAA CCAAGTAGAA GAGAGTAGAA CAGAGTAGAA AGGAGTAGAA CGGAGTAGAA TGGAGTAGAA ACGAGTAGAA GCGAGTAGAA CCGAGTAGAA TCGAGTAGAA GTGAGTAGAA CTGAGTAGAA GACAGTAGAA CACAGTAGAA AGCAGTAGAA GGCAGTAGAA CGCAGTAGAA TGCAGTAGAA ACCAGTAGAA GCCAGTAGAA TCCAGTAGAA GTCAGTAGAA CTCAGTAGAA GGTAGTAGAA CGTAGTAGAA GCTAGTAGAA CCTAGTAGAA GAAGGTAGAA CAAGGTAGAA AGAGGTAGAA GGAGGTAGAA CGAGGTAGAA TGAGGTAGAA ACAGGTAGAA GCAGGTAGAA CCAGGTAGAA TCAGGTAGAA GTAGGTAGAA CTAGGTAGAA AACGGTAGAA GACGGTAGAA CACGGTAGAA TACGGTAGAA AGCGGTAGAA GGCGGTAGAA CGCGGTAGAA TGCGGTAGAA ACCGGTAGAA GCCGGTAGAA TCCGGTAGAA ATCGGTAGAA GTCGGTAGAA CTCGGTAGAA TTCGGTAGAA GATGGTAGAA CATGGTAGAA AGTGGTAGAA GGTGGTAGAA CGTGGTAGAA TGTGGTAGAA ACTGGTAGAA GCTGGTAGAA CCTGGTAGAA TCTGGTAGAA GTTGGTAGAA CTTGGTAGAA GAACGTAGAA CAACGTAGAA AGACGTAGAA GGACGTAGAA CGACGTAGAA TGACGTAGAA ACACGTAGAA GCACGTAGAA CCACGTAGAA TCACGTAGAA GTACGTAGAA CTACGTAGAA AAGCGTAGAA GAGCGTAGAA CAGCGTAGAA TAGCGTAGAA AGGCGTAGAA CGGCGTAGAA TGGCGTAGAA ACGCGTAGAA GCGCGTAGAA CCGCGTAGAA TCGCGTAGAA ATGCGTAGAA GTGCGTAGAA CTGCGTAGAA TTGCGTAGAA AACCGTAGAA GACCGTAGAA CACCGTAGAA TACCGTAGAA AGCCGTAGAA GGCCGTAGAA CGCCGTAGAA TGCCGTAGAA ATCCGTAGAA GTCCGTAGAA CTCCGTAGAA TTCCGTAGAA GATCGTAGAA CATCGTAGAA AGTCGTAGAA GGTCGTAGAA CGTCGTAGAA TGTCGTAGAA ACTCGTAGAA GCTCGTAGAA CCTCGTAGAA TCTCGTAGAA GTTCGTAGAA CTTCGTAGAA GGATGTAGAA CGATGTAGAA GCATGTAGAA CCATGTAGAA GAGTGTAGAA CAGTGTAGAA AGGTGTAGAA CGGTGTAGAA TGGTGTAGAA ACGTGTAGAA GCGTGTAGAA CCGTGTAGAA TCGTGTAGAA GTGTGTAGAA CTGTGTAGAA GACTGTAGAA CACTGTAGAA AGCTGTAGAA GGCTGTAGAA CGCTGTAGAA TGCTGTAGAA ACCTGTAGAA GCCTGTAGAA TCCTGTAGAA GTCTGTAGAA CTCTGTAGAA GGTTGTAGAA CGTTGTAGAA GCTTGTAGAA CCTTGTAGAA GGAACTAGAA CGAACTAGAA GCAACTAGAA CCAACTAGAA GAGACTAGAA CAGACTAGAA AGGACTAGAA CGGACTAGAA TGGACTAGAA ACGACTAGAA GCGACTAGAA CCGACTAGAA TCGACTAGAA GTGACTAGAA CTGACTAGAA GACACTAGAA CACACTAGAA AGCACTAGAA GGCACTAGAA CGCACTAGAA TGCACTAGAA ACCACTAGAA GCCACTAGAA TCCACTAGAA GTCACTAGAA CTCACTAGAA GGTACTAGAA CGTACTAGAA GCTACTAGAA CCTACTAGAA GAAGCTAGAA CAAGCTAGAA AGAGCTAGAA GGAGCTAGAA CGAGCTAGAA TGAGCTAGAA ACAGCTAGAA GCAGCTAGAA CCAGCTAGAA TCAGCTAGAA GTAGCTAGAA CTAGCTAGAA AAGGCTAGAA GAGGCTAGAA CAGGCTAGAA TAGGCTAGAA ACGGCTAGAA GCGGCTAGAA CCGGCTAGAA TCGGCTAGAA ATGGCTAGAA GTGGCTAGAA CTGGCTAGAA TTGGCTAGAA AACGCTAGAA GACGCTAGAA CACGCTAGAA TACGCTAGAA AGCGCTAGAA GGCGCTAGAA CGCGCTAGAA TGCGCTAGAA ACCGCTAGAA GCCGCTAGAA TCCGCTAGAA ATCGCTAGAA GTCGCTAGAA CTCGCTAGAA TTCGCTAGAA GATGCTAGAA CATGCTAGAA AGTGCTAGAA GGTGCTAGAA CGTGCTAGAA TGTGCTAGAA ACTGCTAGAA GCTGCTAGAA CCTGCTAGAA TCTGCTAGAA GTTGCTAGAA CTTGCTAGAA GAACCTAGAA CAACCTAGAA AGACCTAGAA GGACCTAGAA CGACCTAGAA TGACCTAGAA ACACCTAGAA GCACCTAGAA CCACCTAGAA TCACCTAGAA GTACCTAGAA CTACCTAGAA AAGCCTAGAA GAGCCTAGAA CAGCCTAGAA TAGCCTAGAA AGGCCTAGAA CGGCCTAGAA TGGCCTAGAA ACGCCTAGAA GCGCCTAGAA CCGCCTAGAA TCGCCTAGAA ATGCCTAGAA GTGCCTAGAA CTGCCTAGAA TTGCCTAGAA GATCCTAGAA CATCCTAGAA AGTCCTAGAA GGTCCTAGAA CGTCCTAGAA TGTCCTAGAA ACTCCTAGAA GCTCCTAGAA CCTCCTAGAA TCTCCTAGAA GTTCCTAGAA CTTCCTAGAA GGATCTAGAA CGATCTAGAA GCATCTAGAA CCATCTAGAA GAGTCTAGAA CAGTCTAGAA AGGTCTAGAA CGGTCTAGAA TGGTCTAGAA ACGTCTAGAA GCGTCTAGAA CCGTCTAGAA TCGTCTAGAA GTGTCTAGAA CTGTCTAGAA GACTCTAGAA CACTCTAGAA AGCTCTAGAA GGCTCTAGAA CGCTCTAGAA TGCTCTAGAA ACCTCTAGAA GCCTCTAGAA TCCTCTAGAA GTCTCTAGAA CTCTCTAGAA GGTTCTAGAA CGTTCTAGAA GCTTCTAGAA CCTTCTAGAA CGGATTAGAA GCGATTAGAA CCGATTAGAA GGCATTAGAA CGCATTAGAA GCCATTAGAA GGAGTTAGAA CGAGTTAGAA GCAGTTAGAA CCAGTTAGAA GAGGTTAGAA CAGGTTAGAA ACGGTTAGAA GCGGTTAGAA CCGGTTAGAA TCGGTTAGAA GTGGTTAGAA CTGGTTAGAA GACGTTAGAA CACGTTAGAA AGCGTTAGAA GGCGTTAGAA CGCGTTAGAA TGCGTTAGAA ACCGTTAGAA GCCGTTAGAA TCCGTTAGAA GTCGTTAGAA CTCGTTAGAA GGTGTTAGAA CGTGTTAGAA GCTGTTAGAA CCTGTTAGAA GGACTTAGAA CGACTTAGAA GCACTTAGAA CCACTTAGAA GAGCTTAGAA CAGCTTAGAA AGGCTTAGAA CGGCTTAGAA TGGCTTAGAA ACGCTTAGAA GCGCTTAGAA CCGCTTAGAA TCGCTTAGAA GTGCTTAGAA CTGCTTAGAA GACCTTAGAA CACCTTAGAA AGCCTTAGAA GGCCTTAGAA CGCCTTAGAA TGCCTTAGAA GTCCTTAGAA CTCCTTAGAA GGTCTTAGAA CGTCTTAGAA GCTCTTAGAA CCTCTTAGAA GAAGAAGGAA CAAGAAGGAA AGAGAAGGAA GGAGAAGGAA CGAGAAGGAA TGAGAAGGAA ACAGAAGGAA GCAGAAGGAA CCAGAAGGAA TCAGAAGGAA GTAGAAGGAA CTAGAAGGAA AAGGAAGGAA GAGGAAGGAA CAGGAAGGAA TAGGAAGGAA ACGGAAGGAA GCGGAAGGAA CCGGAAGGAA TCGGAAGGAA ATGGAAGGAA GTGGAAGGAA CTGGAAGGAA TTGGAAGGAA AACGAAGGAA GACGAAGGAA CACGAAGGAA TACGAAGGAA AGCGAAGGAA GGCGAAGGAA CGCGAAGGAA TGCGAAGGAA ACCGAAGGAA GCCGAAGGAA TCCGAAGGAA ATCGAAGGAA GTCGAAGGAA CTCGAAGGAA TTCGAAGGAA GATGAAGGAA CATGAAGGAA AGTGAAGGAA GGTGAAGGAA CGTGAAGGAA TGTGAAGGAA ACTGAAGGAA GCTGAAGGAA CCTGAAGGAA TCTGAAGGAA GTTGAAGGAA CTTGAAGGAA GAACAAGGAA CAACAAGGAA AGACAAGGAA GGACAAGGAA CGACAAGGAA TGACAAGGAA ACACAAGGAA GCACAAGGAA CCACAAGGAA TCACAAGGAA GTACAAGGAA CTACAAGGAA AAGCAAGGAA GAGCAAGGAA CAGCAAGGAA TAGCAAGGAA AGGCAAGGAA CGGCAAGGAA TGGCAAGGAA ACGCAAGGAA GCGCAAGGAA CCGCAAGGAA TCGCAAGGAA ATGCAAGGAA GTGCAAGGAA CTGCAAGGAA TTGCAAGGAA AACCAAGGAA GACCAAGGAA CACCAAGGAA TACCAAGGAA AGCCAAGGAA GGCCAAGGAA CGCCAAGGAA TGCCAAGGAA ATCCAAGGAA GTCCAAGGAA CTCCAAGGAA TTCCAAGGAA GATCAAGGAA CATCAAGGAA AGTCAAGGAA GGTCAAGGAA CGTCAAGGAA TGTCAAGGAA ACTCAAGGAA GCTCAAGGAA CCTCAAGGAA TCTCAAGGAA GTTCAAGGAA CTTCAAGGAA GGATAAGGAA CGATAAGGAA GCATAAGGAA CCATAAGGAA GAGTAAGGAA CAGTAAGGAA AGGTAAGGAA CGGTAAGGAA TGGTAAGGAA ACGTAAGGAA GCGTAAGGAA CCGTAAGGAA TCGTAAGGAA GTGTAAGGAA CTGTAAGGAA GACTAAGGAA CACTAAGGAA AGCTAAGGAA GGCTAAGGAA CGCTAAGGAA TGCTAAGGAA ACCTAAGGAA GCCTAAGGAA TCCTAAGGAA GTCTAAGGAA CTCTAAGGAA GGTTAAGGAA CGTTAAGGAA GCTTAAGGAA CCTTAAGGAA AGAAGAGGAA GGAAGAGGAA CGAAGAGGAA TGAAGAGGAA ACAAGAGGAA GCAAGAGGAA CCAAGAGGAA TCAAGAGGAA GTAAGAGGAA CTAAGAGGAA AAGAGAGGAA GAGAGAGGAA CAGAGAGGAA TAGAGAGGAA AGGAGAGGAA CGGAGAGGAA TGGAGAGGAA ACGAGAGGAA GCGAGAGGAA CCGAGAGGAA TCGAGAGGAA ATGAGAGGAA GTGAGAGGAA CTGAGAGGAA TTGAGAGGAA AACAGAGGAA GACAGAGGAA CACAGAGGAA TACAGAGGAA AGCAGAGGAA GGCAGAGGAA CGCAGAGGAA TGCAGAGGAA ACCAGAGGAA GCCAGAGGAA TCCAGAGGAA ATCAGAGGAA GTCAGAGGAA CTCAGAGGAA TTCAGAGGAA GATAGAGGAA CATAGAGGAA AGTAGAGGAA GGTAGAGGAA CGTAGAGGAA TGTAGAGGAA ACTAGAGGAA GCTAGAGGAA CCTAGAGGAA TCTAGAGGAA GTTAGAGGAA CTTAGAGGAA GAAGGAGGAA CAAGGAGGAA TAAGGAGGAA AGAGGAGGAA GGAGGAGGAA CGAGGAGGAA TGAGGAGGAA ACAGGAGGAA GCAGGAGGAA CCAGGAGGAA TCAGGAGGAA ATAGGAGGAA GTAGGAGGAA CTAGGAGGAA TTAGGAGGAA AACGGAGGAA GACGGAGGAA CACGGAGGAA TACGGAGGAA AGCGGAGGAA TGCGGAGGAA ACCGGAGGAA TCCGGAGGAA ATCGGAGGAA GTCGGAGGAA CTCGGAGGAA TTCGGAGGAA AATGGAGGAA GATGGAGGAA CATGGAGGAA TATGGAGGAA AGTGGAGGAA GGTGGAGGAA CGTGGAGGAA TGTGGAGGAA ACTGGAGGAA GCTGGAGGAA CCTGGAGGAA TCTGGAGGAA ATTGGAGGAA GTTGGAGGAA CTTGGAGGAA GAACGAGGAA CAACGAGGAA TAACGAGGAA AGACGAGGAA GGACGAGGAA CGACGAGGAA TGACGAGGAA ACACGAGGAA GCACGAGGAA CCACGAGGAA TCACGAGGAA ATACGAGGAA GTACGAGGAA CTACGAGGAA TTACGAGGAA AAGCGAGGAA GAGCGAGGAA CAGCGAGGAA TAGCGAGGAA AGGCGAGGAA TGGCGAGGAA ACGCGAGGAA TCGCGAGGAA ATGCGAGGAA GTGCGAGGAA CTGCGAGGAA TTGCGAGGAA AACCGAGGAA GACCGAGGAA CACCGAGGAA TACCGAGGAA AGCCGAGGAA TGCCGAGGAA ATCCGAGGAA GTCCGAGGAA CTCCGAGGAA TTCCGAGGAA AATCGAGGAA GATCGAGGAA CATCGAGGAA TATCGAGGAA AGTCGAGGAA GGTCGAGGAA CGTCGAGGAA TGTCGAGGAA ACTCGAGGAA GCTCGAGGAA CCTCGAGGAA TCTCGAGGAA ATTCGAGGAA GTTCGAGGAA CTTCGAGGAA GAATGAGGAA CAATGAGGAA AGATGAGGAA GGATGAGGAA CGATGAGGAA TGATGAGGAA ACATGAGGAA GCATGAGGAA CCATGAGGAA TCATGAGGAA GTATGAGGAA CTATGAGGAA AAGTGAGGAA GAGTGAGGAA CAGTGAGGAA TAGTGAGGAA AGGTGAGGAA CGGTGAGGAA TGGTGAGGAA ACGTGAGGAA GCGTGAGGAA CCGTGAGGAA TCGTGAGGAA ATGTGAGGAA GTGTGAGGAA CTGTGAGGAA TTGTGAGGAA AACTGAGGAA GACTGAGGAA CACTGAGGAA TACTGAGGAA AGCTGAGGAA GGCTGAGGAA CGCTGAGGAA TGCTGAGGAA ACCTGAGGAA GCCTGAGGAA TCCTGAGGAA ATCTGAGGAA GTCTGAGGAA CTCTGAGGAA TTCTGAGGAA GATTGAGGAA CATTGAGGAA AGTTGAGGAA GGTTGAGGAA CGTTGAGGAA TGTTGAGGAA ACTTGAGGAA GCTTGAGGAA CCTTGAGGAA TCTTGAGGAA AGAACAGGAA GGAACAGGAA CGAACAGGAA TGAACAGGAA ACAACAGGAA GCAACAGGAA CCAACAGGAA TCAACAGGAA GTAACAGGAA CTAACAGGAA AAGACAGGAA GAGACAGGAA CAGACAGGAA TAGACAGGAA AGGACAGGAA CGGACAGGAA TGGACAGGAA ACGACAGGAA GCGACAGGAA CCGACAGGAA TCGACAGGAA ATGACAGGAA GTGACAGGAA CTGACAGGAA TTGACAGGAA AACACAGGAA GACACAGGAA CACACAGGAA TACACAGGAA AGCACAGGAA GGCACAGGAA CGCACAGGAA TGCACAGGAA ACCACAGGAA GCCACAGGAA TCCACAGGAA ATCACAGGAA GTCACAGGAA CTCACAGGAA TTCACAGGAA GATACAGGAA CATACAGGAA AGTACAGGAA GGTACAGGAA CGTACAGGAA TGTACAGGAA ACTACAGGAA GCTACAGGAA CCTACAGGAA TCTACAGGAA GTTACAGGAA CTTACAGGAA GAAGCAGGAA CAAGCAGGAA TAAGCAGGAA AGAGCAGGAA GGAGCAGGAA CGAGCAGGAA TGAGCAGGAA ACAGCAGGAA GCAGCAGGAA CCAGCAGGAA TCAGCAGGAA ATAGCAGGAA GTAGCAGGAA CTAGCAGGAA TTAGCAGGAA AAGGCAGGAA GAGGCAGGAA CAGGCAGGAA TAGGCAGGAA ACGGCAGGAA TCGGCAGGAA ATGGCAGGAA GTGGCAGGAA CTGGCAGGAA TTGGCAGGAA AACGCAGGAA GACGCAGGAA CACGCAGGAA TACGCAGGAA AGCGCAGGAA TGCGCAGGAA ACCGCAGGAA TCCGCAGGAA ATCGCAGGAA GTCGCAGGAA CTCGCAGGAA TTCGCAGGAA AATGCAGGAA GATGCAGGAA CATGCAGGAA TATGCAGGAA AGTGCAGGAA GGTGCAGGAA CGTGCAGGAA TGTGCAGGAA ACTGCAGGAA GCTGCAGGAA CCTGCAGGAA TCTGCAGGAA ATTGCAGGAA GTTGCAGGAA CTTGCAGGAA GAACCAGGAA CAACCAGGAA TAACCAGGAA AGACCAGGAA GGACCAGGAA CGACCAGGAA TGACCAGGAA ACACCAGGAA GCACCAGGAA CCACCAGGAA TCACCAGGAA ATACCAGGAA GTACCAGGAA CTACCAGGAA TTACCAGGAA AAGCCAGGAA GAGCCAGGAA CAGCCAGGAA TAGCCAGGAA AGGCCAGGAA TGGCCAGGAA ACGCCAGGAA TCGCCAGGAA ATGCCAGGAA GTGCCAGGAA CTGCCAGGAA TTGCCAGGAA AATCCAGGAA GATCCAGGAA CATCCAGGAA TATCCAGGAA AGTCCAGGAA GGTCCAGGAA CGTCCAGGAA TGTCCAGGAA ACTCCAGGAA GCTCCAGGAA CCTCCAGGAA TCTCCAGGAA ATTCCAGGAA GTTCCAGGAA CTTCCAGGAA GAATCAGGAA CAATCAGGAA AGATCAGGAA GGATCAGGAA CGATCAGGAA TGATCAGGAA ACATCAGGAA GCATCAGGAA CCATCAGGAA TCATCAGGAA GTATCAGGAA CTATCAGGAA AAGTCAGGAA GAGTCAGGAA CAGTCAGGAA TAGTCAGGAA AGGTCAGGAA CGGTCAGGAA TGGTCAGGAA ACGTCAGGAA GCGTCAGGAA CCGTCAGGAA TCGTCAGGAA ATGTCAGGAA GTGTCAGGAA CTGTCAGGAA TTGTCAGGAA AACTCAGGAA GACTCAGGAA CACTCAGGAA TACTCAGGAA AGCTCAGGAA GGCTCAGGAA CGCTCAGGAA TGCTCAGGAA ACCTCAGGAA GCCTCAGGAA TCCTCAGGAA ATCTCAGGAA GTCTCAGGAA CTCTCAGGAA TTCTCAGGAA GATTCAGGAA CATTCAGGAA AGTTCAGGAA GGTTCAGGAA CGTTCAGGAA TGTTCAGGAA ACTTCAGGAA GCTTCAGGAA CCTTCAGGAA TCTTCAGGAA GGAATAGGAA CGAATAGGAA GCAATAGGAA CCAATAGGAA GAGATAGGAA CAGATAGGAA AGGATAGGAA CGGATAGGAA TGGATAGGAA ACGATAGGAA GCGATAGGAA CCGATAGGAA TCGATAGGAA GTGATAGGAA CTGATAGGAA GACATAGGAA CACATAGGAA AGCATAGGAA GGCATAGGAA CGCATAGGAA TGCATAGGAA ACCATAGGAA GCCATAGGAA TCCATAGGAA GTCATAGGAA CTCATAGGAA GGTATAGGAA CGTATAGGAA GCTATAGGAA CCTATAGGAA GAAGTAGGAA CAAGTAGGAA AGAGTAGGAA GGAGTAGGAA CGAGTAGGAA TGAGTAGGAA ACAGTAGGAA GCAGTAGGAA CCAGTAGGAA TCAGTAGGAA GTAGTAGGAA CTAGTAGGAA AAGGTAGGAA GAGGTAGGAA CAGGTAGGAA TAGGTAGGAA ACGGTAGGAA GCGGTAGGAA CCGGTAGGAA TCGGTAGGAA ATGGTAGGAA GTGGTAGGAA CTGGTAGGAA TTGGTAGGAA AACGTAGGAA GACGTAGGAA CACGTAGGAA TACGTAGGAA AGCGTAGGAA GGCGTAGGAA CGCGTAGGAA TGCGTAGGAA ACCGTAGGAA GCCGTAGGAA TCCGTAGGAA ATCGTAGGAA GTCGTAGGAA CTCGTAGGAA TTCGTAGGAA GATGTAGGAA CATGTAGGAA AGTGTAGGAA GGTGTAGGAA CGTGTAGGAA TGTGTAGGAA ACTGTAGGAA GCTGTAGGAA CCTGTAGGAA TCTGTAGGAA GTTGTAGGAA CTTGTAGGAA GAACTAGGAA CAACTAGGAA AGACTAGGAA GGACTAGGAA CGACTAGGAA TGACTAGGAA ACACTAGGAA GCACTAGGAA CCACTAGGAA TCACTAGGAA GTACTAGGAA CTACTAGGAA AAGCTAGGAA GAGCTAGGAA CAGCTAGGAA TAGCTAGGAA AGGCTAGGAA CGGCTAGGAA TGGCTAGGAA ACGCTAGGAA GCGCTAGGAA CCGCTAGGAA TCGCTAGGAA ATGCTAGGAA GTGCTAGGAA CTGCTAGGAA TTGCTAGGAA AACCTAGGAA GACCTAGGAA CACCTAGGAA TACCTAGGAA AGCCTAGGAA GGCCTAGGAA CGCCTAGGAA TGCCTAGGAA ATCCTAGGAA GTCCTAGGAA CTCCTAGGAA GATCTAGGAA CATCTAGGAA AGTCTAGGAA GGTCTAGGAA CGTCTAGGAA TGTCTAGGAA ACTCTAGGAA GCTCTAGGAA CCTCTAGGAA TCTCTAGGAA GTTCTAGGAA CTTCTAGGAA GGATTAGGAA CGATTAGGAA GCATTAGGAA CCATTAGGAA GAGTTAGGAA CAGTTAGGAA AGGTTAGGAA CGGTTAGGAA TGGTTAGGAA ACGTTAGGAA GCGTTAGGAA CCGTTAGGAA TCGTTAGGAA GTGTTAGGAA CTGTTAGGAA GACTTAGGAA CACTTAGGAA AGCTTAGGAA GGCTTAGGAA CGCTTAGGAA TGCTTAGGAA ACCTTAGGAA GCCTTAGGAA TCCTTAGGAA GTCTTAGGAA CTCTTAGGAA AAGAACGGAA GAGAACGGAA CAGAACGGAA TAGAACGGAA AGGAACGGAA CGGAACGGAA TGGAACGGAA ACGAACGGAA GCGAACGGAA CCGAACGGAA TCGAACGGAA ATGAACGGAA GTGAACGGAA CTGAACGGAA TTGAACGGAA AACAACGGAA GACAACGGAA CACAACGGAA TACAACGGAA AGCAACGGAA GGCAACGGAA CGCAACGGAA TGCAACGGAA ACCAACGGAA GCCAACGGAA TCCAACGGAA ATCAACGGAA GTCAACGGAA CTCAACGGAA TTCAACGGAA GATAACGGAA CATAACGGAA AGTAACGGAA GGTAACGGAA CGTAACGGAA TGTAACGGAA ACTAACGGAA GCTAACGGAA CCTAACGGAA TCTAACGGAA GTTAACGGAA CTTAACGGAA GAAGACGGAA CAAGACGGAA TAAGACGGAA AGAGACGGAA GGAGACGGAA CGAGACGGAA TGAGACGGAA ACAGACGGAA GCAGACGGAA CCAGACGGAA TCAGACGGAA ATAGACGGAA GTAGACGGAA CTAGACGGAA TTAGACGGAA AAGGACGGAA GAGGACGGAA CAGGACGGAA TAGGACGGAA ACGGACGGAA TCGGACGGAA ATGGACGGAA GTGGACGGAA CTGGACGGAA TTGGACGGAA AACGACGGAA GACGACGGAA CACGACGGAA TACGACGGAA AGCGACGGAA TGCGACGGAA ACCGACGGAA TCCGACGGAA ATCGACGGAA GTCGACGGAA CTCGACGGAA TTCGACGGAA AATGACGGAA GATGACGGAA CATGACGGAA TATGACGGAA AGTGACGGAA GGTGACGGAA CGTGACGGAA TGTGACGGAA ACTGACGGAA GCTGACGGAA CCTGACGGAA TCTGACGGAA ATTGACGGAA GTTGACGGAA CTTGACGGAA GAACACGGAA CAACACGGAA TAACACGGAA AGACACGGAA GGACACGGAA CGACACGGAA TGACACGGAA ACACACGGAA GCACACGGAA CCACACGGAA TCACACGGAA ATACACGGAA GTACACGGAA CTACACGGAA TTACACGGAA AAGCACGGAA GAGCACGGAA CAGCACGGAA TAGCACGGAA AGGCACGGAA TGGCACGGAA ACGCACGGAA TCGCACGGAA ATGCACGGAA GTGCACGGAA CTGCACGGAA TTGCACGGAA AACCACGGAA GACCACGGAA CACCACGGAA TACCACGGAA AGCCACGGAA TGCCACGGAA ATCCACGGAA GTCCACGGAA CTCCACGGAA TTCCACGGAA AATCACGGAA GATCACGGAA CATCACGGAA TATCACGGAA AGTCACGGAA GGTCACGGAA CGTCACGGAA TGTCACGGAA ACTCACGGAA GCTCACGGAA CCTCACGGAA TCTCACGGAA ATTCACGGAA GTTCACGGAA CTTCACGGAA GAATACGGAA CAATACGGAA AGATACGGAA GGATACGGAA CGATACGGAA TGATACGGAA ACATACGGAA GCATACGGAA CCATACGGAA TCATACGGAA GTATACGGAA CTATACGGAA AAGTACGGAA GAGTACGGAA CAGTACGGAA TAGTACGGAA AGGTACGGAA CGGTACGGAA TGGTACGGAA ACGTACGGAA GCGTACGGAA CCGTACGGAA TCGTACGGAA ATGTACGGAA GTGTACGGAA CTGTACGGAA TTGTACGGAA AACTACGGAA GACTACGGAA CACTACGGAA TACTACGGAA AGCTACGGAA GGCTACGGAA CGCTACGGAA TGCTACGGAA ACCTACGGAA GCCTACGGAA TCCTACGGAA ATCTACGGAA GTCTACGGAA CTCTACGGAA TTCTACGGAA GATTACGGAA CATTACGGAA AGTTACGGAA GGTTACGGAA CGTTACGGAA TGTTACGGAA ACTTACGGAA GCTTACGGAA CCTTACGGAA TCTTACGGAA AGAAGCGGAA GGAAGCGGAA CGAAGCGGAA TGAAGCGGAA ACAAGCGGAA GCAAGCGGAA CCAAGCGGAA TCAAGCGGAA ATAAGCGGAA GTAAGCGGAA CTAAGCGGAA TTAAGCGGAA AAGAGCGGAA GAGAGCGGAA CAGAGCGGAA TAGAGCGGAA AGGAGCGGAA TGGAGCGGAA ACGAGCGGAA TCGAGCGGAA ATGAGCGGAA GTGAGCGGAA CTGAGCGGAA TTGAGCGGAA AACAGCGGAA GACAGCGGAA CACAGCGGAA TACAGCGGAA AGCAGCGGAA TGCAGCGGAA ACCAGCGGAA TCCAGCGGAA ATCAGCGGAA GTCAGCGGAA CTCAGCGGAA TTCAGCGGAA AATAGCGGAA GATAGCGGAA CATAGCGGAA TATAGCGGAA AGTAGCGGAA GGTAGCGGAA CGTAGCGGAA TGTAGCGGAA ACTAGCGGAA GCTAGCGGAA CCTAGCGGAA TCTAGCGGAA ATTAGCGGAA GTTAGCGGAA CTTAGCGGAA GAAGGCGGAA CAAGGCGGAA TAAGGCGGAA AGAGGCGGAA TGAGGCGGAA ACAGGCGGAA TCAGGCGGAA ATAGGCGGAA GTAGGCGGAA CTAGGCGGAA TTAGGCGGAA AACGGCGGAA TACGGCGGAA ATCGGCGGAA TTCGGCGGAA AATGGCGGAA GATGGCGGAA CATGGCGGAA TATGGCGGAA AGTGGCGGAA TGTGGCGGAA ACTGGCGGAA TCTGGCGGAA ATTGGCGGAA GTTGGCGGAA CTTGGCGGAA GAACGCGGAA CAACGCGGAA TAACGCGGAA AGACGCGGAA TGACGCGGAA ACACGCGGAA TCACGCGGAA ATACGCGGAA GTACGCGGAA CTACGCGGAA TTACGCGGAA AAGCGCGGAA TAGCGCGGAA ATGCGCGGAA TTGCGCGGAA AACCGCGGAA TACCGCGGAA ATCCGCGGAA AATCGCGGAA GATCGCGGAA CATCGCGGAA TATCGCGGAA AGTCGCGGAA TGTCGCGGAA ACTCGCGGAA TCTCGCGGAA ATTCGCGGAA GTTCGCGGAA CTTCGCGGAA GAATGCGGAA CAATGCGGAA TAATGCGGAA AGATGCGGAA GGATGCGGAA CGATGCGGAA TGATGCGGAA ACATGCGGAA GCATGCGGAA CCATGCGGAA TCATGCGGAA ATATGCGGAA GTATGCGGAA CTATGCGGAA TTATGCGGAA AAGTGCGGAA GAGTGCGGAA CAGTGCGGAA TAGTGCGGAA AGGTGCGGAA TGGTGCGGAA ACGTGCGGAA TCGTGCGGAA ATGTGCGGAA GTGTGCGGAA CTGTGCGGAA TTGTGCGGAA AACTGCGGAA GACTGCGGAA CACTGCGGAA TACTGCGGAA AGCTGCGGAA TGCTGCGGAA ACCTGCGGAA TCCTGCGGAA ATCTGCGGAA GTCTGCGGAA CTCTGCGGAA TTCTGCGGAA AATTGCGGAA GATTGCGGAA CATTGCGGAA TATTGCGGAA AGTTGCGGAA GGTTGCGGAA CGTTGCGGAA TGTTGCGGAA ACTTGCGGAA GCTTGCGGAA CCTTGCGGAA TCTTGCGGAA AGAACCGGAA GGAACCGGAA CGAACCGGAA TGAACCGGAA ACAACCGGAA GCAACCGGAA CCAACCGGAA TCAACCGGAA ATAACCGGAA GTAACCGGAA CTAACCGGAA TTAACCGGAA AAGACCGGAA GAGACCGGAA CAGACCGGAA TAGACCGGAA AGGACCGGAA TGGACCGGAA ACGACCGGAA TCGACCGGAA ATGACCGGAA GTGACCGGAA CTGACCGGAA TTGACCGGAA AACACCGGAA GACACCGGAA CACACCGGAA TACACCGGAA AGCACCGGAA TGCACCGGAA ACCACCGGAA TCCACCGGAA ATCACCGGAA GTCACCGGAA CTCACCGGAA TTCACCGGAA AATACCGGAA GATACCGGAA CATACCGGAA TATACCGGAA AGTACCGGAA GGTACCGGAA CGTACCGGAA TGTACCGGAA ACTACCGGAA GCTACCGGAA CCTACCGGAA TCTACCGGAA ATTACCGGAA GTTACCGGAA CTTACCGGAA GAAGCCGGAA CAAGCCGGAA TAAGCCGGAA AGAGCCGGAA TGAGCCGGAA ACAGCCGGAA TCAGCCGGAA ATAGCCGGAA GTAGCCGGAA CTAGCCGGAA TTAGCCGGAA AAGGCCGGAA TAGGCCGGAA ATGGCCGGAA TTGGCCGGAA AACGCCGGAA TACGCCGGAA ATCGCCGGAA TTCGCCGGAA AATGCCGGAA GATGCCGGAA CATGCCGGAA TATGCCGGAA AGTGCCGGAA TGTGCCGGAA ACTGCCGGAA TCTGCCGGAA ATTGCCGGAA GTTGCCGGAA CTTGCCGGAA GAATCCGGAA CAATCCGGAA TAATCCGGAA AGATCCGGAA GGATCCGGAA CGATCCGGAA TGATCCGGAA ACATCCGGAA GCATCCGGAA CCATCCGGAA TCATCCGGAA ATATCCGGAA GTATCCGGAA CTATCCGGAA TTATCCGGAA AAGTCCGGAA GAGTCCGGAA CAGTCCGGAA TAGTCCGGAA AGGTCCGGAA TGGTCCGGAA ACGTCCGGAA TCGTCCGGAA ATGTCCGGAA GTGTCCGGAA CTGTCCGGAA TTGTCCGGAA AACTCCGGAA GACTCCGGAA CACTCCGGAA TACTCCGGAA AGCTCCGGAA TGCTCCGGAA ACCTCCGGAA TCCTCCGGAA ATCTCCGGAA GTCTCCGGAA CTCTCCGGAA TTCTCCGGAA AATTCCGGAA GATTCCGGAA CATTCCGGAA TATTCCGGAA AGTTCCGGAA GGTTCCGGAA CGTTCCGGAA TGTTCCGGAA ACTTCCGGAA GCTTCCGGAA CCTTCCGGAA TCTTCCGGAA AGAATCGGAA GGAATCGGAA CGAATCGGAA TGAATCGGAA ACAATCGGAA GCAATCGGAA CCAATCGGAA TCAATCGGAA GTAATCGGAA CTAATCGGAA AAGATCGGAA GAGATCGGAA CAGATCGGAA TAGATCGGAA AGGATCGGAA CGGATCGGAA TGGATCGGAA ACGATCGGAA GCGATCGGAA CCGATCGGAA TCGATCGGAA ATGATCGGAA GTGATCGGAA CTGATCGGAA TTGATCGGAA AACATCGGAA GACATCGGAA CACATCGGAA TACATCGGAA AGCATCGGAA GGCATCGGAA CGCATCGGAA TGCATCGGAA ACCATCGGAA GCCATCGGAA TCCATCGGAA ATCATCGGAA GTCATCGGAA CTCATCGGAA TTCATCGGAA GATATCGGAA CATATCGGAA AGTATCGGAA GGTATCGGAA CGTATCGGAA TGTATCGGAA ACTATCGGAA GCTATCGGAA CCTATCGGAA TCTATCGGAA GTTATCGGAA CTTATCGGAA GAAGTCGGAA CAAGTCGGAA TAAGTCGGAA AGAGTCGGAA GGAGTCGGAA CGAGTCGGAA TGAGTCGGAA ACAGTCGGAA GCAGTCGGAA CCAGTCGGAA TCAGTCGGAA ATAGTCGGAA GTAGTCGGAA CTAGTCGGAA TTAGTCGGAA AAGGTCGGAA GAGGTCGGAA CAGGTCGGAA TAGGTCGGAA ACGGTCGGAA TCGGTCGGAA ATGGTCGGAA GTGGTCGGAA CTGGTCGGAA TTGGTCGGAA AACGTCGGAA GACGTCGGAA CACGTCGGAA TACGTCGGAA AGCGTCGGAA TGCGTCGGAA ACCGTCGGAA TCCGTCGGAA ATCGTCGGAA GTCGTCGGAA CTCGTCGGAA TTCGTCGGAA AATGTCGGAA GATGTCGGAA CATGTCGGAA TATGTCGGAA AGTGTCGGAA GGTGTCGGAA CGTGTCGGAA TGTGTCGGAA ACTGTCGGAA GCTGTCGGAA CCTGTCGGAA TCTGTCGGAA ATTGTCGGAA GTTGTCGGAA CTTGTCGGAA GAACTCGGAA CAACTCGGAA TAACTCGGAA AGACTCGGAA GGACTCGGAA CGACTCGGAA TGACTCGGAA ACACTCGGAA GCACTCGGAA CCACTCGGAA TCACTCGGAA ATACTCGGAA GTACTCGGAA CTACTCGGAA TTACTCGGAA AAGCTCGGAA GAGCTCGGAA CAGCTCGGAA TAGCTCGGAA AGGCTCGGAA TGGCTCGGAA ACGCTCGGAA TCGCTCGGAA ATGCTCGGAA GTGCTCGGAA CTGCTCGGAA TTGCTCGGAA AACCTCGGAA GACCTCGGAA CACCTCGGAA TACCTCGGAA AGCCTCGGAA TGCCTCGGAA ATCCTCGGAA GTCCTCGGAA CTCCTCGGAA TTCCTCGGAA AATCTCGGAA GATCTCGGAA CATCTCGGAA TATCTCGGAA AGTCTCGGAA GGTCTCGGAA CGTCTCGGAA TGTCTCGGAA ACTCTCGGAA GCTCTCGGAA CCTCTCGGAA TCTCTCGGAA ATTCTCGGAA GTTCTCGGAA CTTCTCGGAA GAATTCGGAA CAATTCGGAA AGATTCGGAA GGATTCGGAA CGATTCGGAA TGATTCGGAA ACATTCGGAA GCATTCGGAA CCATTCGGAA TCATTCGGAA GTATTCGGAA CTATTCGGAA AAGTTCGGAA GAGTTCGGAA CAGTTCGGAA TAGTTCGGAA AGGTTCGGAA CGGTTCGGAA TGGTTCGGAA ACGTTCGGAA GCGTTCGGAA CCGTTCGGAA TCGTTCGGAA ATGTTCGGAA GTGTTCGGAA CTGTTCGGAA TTGTTCGGAA AACTTCGGAA GACTTCGGAA CACTTCGGAA TACTTCGGAA AGCTTCGGAA GGCTTCGGAA CGCTTCGGAA TGCTTCGGAA ACCTTCGGAA GCCTTCGGAA TCCTTCGGAA ATCTTCGGAA GTCTTCGGAA CTCTTCGGAA TTCTTCGGAA GAGAATGGAA CAGAATGGAA AGGAATGGAA CGGAATGGAA TGGAATGGAA ACGAATGGAA GCGAATGGAA CCGAATGGAA TCGAATGGAA +GENE1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 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