Mercurial > repos > hackdna > pathprint
diff consensus.xml @ 0:0cebe436a553 draft default tip
Initial upload.
author | hackdna |
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date | Fri, 17 May 2013 14:29:33 -0400 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/consensus.xml Fri May 17 14:29:33 2013 -0400 @@ -0,0 +1,43 @@ +<tool id="pathprint-consensus" name="Create a Consensus"> + <command>consensus.r $input $threshold $output</command> + + <inputs> + <param name="input" type="data" label="Pathway Fingerprint" help="Submit a Pathway Fingerprint file from your history"/> + + <param name="threshold" type="select" label="Threshold" help="Select a threshold value"> + <option value="0.9">0.9</option> + <option value="0.8" selected="true">0.8 (default)</option> + <option value="0.7">0.7</option> + <option value="0.6">0.6</option> + <option value="0.5">0.5</option> + </param> + </inputs> + + <outputs> + <data format="tabular" name="output" label="Consensus Fingerprint"/> + </outputs> + + <stdio> + <exit_code range="1:" level="fatal" /> + </stdio> + + <help> + +**What it does** + +This tool identifies the most prevalent PathPrint value for each pathway across the submitted samples and produces a consensus PathPrint. + +The method calculates the mean value of the pathway activities across samples, and then applies the threshold such that if the mean is greater than threshold, the pathway is assigned a consensus of +1. If the mean is less than -threshold, a value of -1 is assigned. Otherwise, the consensus is assigned a value of 0. + +----- + +**Input:** PathPrint fingerprint for multiple samples and a threshold value. + +**Output:** A single consensus PathPrint fingerprint representing the most commonly occurring value + +----- + +Feedback is welcome. Please send your questions, comments and suggestions to scde@hsci.harvard.edu. + </help> +</tool> +