Mercurial > repos > hackdna > pathprint
comparison consensus.xml @ 0:0cebe436a553 draft default tip
Initial upload.
author | hackdna |
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date | Fri, 17 May 2013 14:29:33 -0400 |
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-1:000000000000 | 0:0cebe436a553 |
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1 <tool id="pathprint-consensus" name="Create a Consensus"> | |
2 <command>consensus.r $input $threshold $output</command> | |
3 | |
4 <inputs> | |
5 <param name="input" type="data" label="Pathway Fingerprint" help="Submit a Pathway Fingerprint file from your history"/> | |
6 | |
7 <param name="threshold" type="select" label="Threshold" help="Select a threshold value"> | |
8 <option value="0.9">0.9</option> | |
9 <option value="0.8" selected="true">0.8 (default)</option> | |
10 <option value="0.7">0.7</option> | |
11 <option value="0.6">0.6</option> | |
12 <option value="0.5">0.5</option> | |
13 </param> | |
14 </inputs> | |
15 | |
16 <outputs> | |
17 <data format="tabular" name="output" label="Consensus Fingerprint"/> | |
18 </outputs> | |
19 | |
20 <stdio> | |
21 <exit_code range="1:" level="fatal" /> | |
22 </stdio> | |
23 | |
24 <help> | |
25 | |
26 **What it does** | |
27 | |
28 This tool identifies the most prevalent PathPrint value for each pathway across the submitted samples and produces a consensus PathPrint. | |
29 | |
30 The method calculates the mean value of the pathway activities across samples, and then applies the threshold such that if the mean is greater than threshold, the pathway is assigned a consensus of +1. If the mean is less than -threshold, a value of -1 is assigned. Otherwise, the consensus is assigned a value of 0. | |
31 | |
32 ----- | |
33 | |
34 **Input:** PathPrint fingerprint for multiple samples and a threshold value. | |
35 | |
36 **Output:** A single consensus PathPrint fingerprint representing the most commonly occurring value | |
37 | |
38 ----- | |
39 | |
40 Feedback is welcome. Please send your questions, comments and suggestions to scde@hsci.harvard.edu. | |
41 </help> | |
42 </tool> | |
43 |