Mercurial > repos > galaxyp > quantp
changeset 0:f1db758949f4 draft
planemo upload commit a0e968c7bd2b6f7b963baeecb08f3a39e50f52d6
| author | galaxyp |
|---|---|
| date | Fri, 14 Sep 2018 12:22:13 -0400 |
| parents | |
| children | dec87511835e |
| files | quantp.r quantp.xml test-data/exp_design_file.tabular test-data/output.html test-data/protein_data.tabular test-data/transcript_data.tabular |
| diffstat | 6 files changed, 6996 insertions(+), 0 deletions(-) [+] |
line wrap: on
line diff
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/quantp.r Fri Sep 14 12:22:13 2018 -0400 @@ -0,0 +1,1004 @@ +#*************************************************************************************************************************************** +# Functions: Start +#*************************************************************************************************************************************** + +#=============================================================================== +# PCA +#=============================================================================== +multisample_PCA = function(df, sampleinfo_df, outfile) +{ + tempdf = df[,-1]; + tempcol = colnames(tempdf); + tempgrp = sampleinfo_df[tempcol,2]; + tempdf = t(tempdf) %>% as.data.frame(); + tempdf[is.na(tempdf)] = 0; + tempdf$Group = tempgrp; + png(outfile, width = 6, height = 6, units = 'in', res=300); + # bitmap(outfile, "png16m"); + g = autoplot(prcomp(select(tempdf, -Group)), data = tempdf, colour = 'Group', size=3); + plot(g); + dev.off(); +} + +#=============================================================================== +# Regression and Cook's distance +#=============================================================================== +singlesample_regression = function(PE_TE_data,htmloutfile, append=TRUE) +{ + rownames(PE_TE_data) = PE_TE_data$PE_ID; + regmodel = lm(PE_abundance~TE_abundance, data=PE_TE_data); + regmodel_summary = summary(regmodel); + + cat("<font><h3>Linear Regression model fit between Proteome and Transcriptome data</h3></font>\n", + "<p>Assuming a linear relationship between Proteome and Transcriptome data, we here fit a linear regression model.</p>\n", + '<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Value</font></th></tr>\n', + file = htmloutfile, append = TRUE); + + cat("<tr><td>Formula</td><td>","PE_abundance~TE_abundance","</td></tr>\n", + "<tr><td colspan='2' align='center'> <b>Coefficients</b></td>","</tr>\n", + "<tr><td>",names(regmodel$coefficients[1]),"</td><td>",regmodel$coefficients[1]," (Pvalue:", regmodel_summary$coefficients[1,4],")","</td></tr>\n", + "<tr><td>",names(regmodel$coefficients[2]),"</td><td>",regmodel$coefficients[2]," (Pvalue:", regmodel_summary$coefficients[2,4],")","</td></tr>\n", + "<tr><td colspan='2' align='center'> <b>Model parameters</b></td>","</tr>\n", + "<tr><td>Residual standard error</td><td>",regmodel_summary$sigma," (",regmodel_summary$df[2]," degree of freedom)</td></tr>\n", + "<tr><td>F-statistic</td><td>",regmodel_summary$fstatistic[1]," ( on ",regmodel_summary$fstatistic[2]," and ",regmodel_summary$fstatistic[3]," degree of freedom)</td></tr>\n", + "<tr><td>R-squared</td><td>",regmodel_summary$r.squared,"</td></tr>\n", + "<tr><td>Adjusted R-squared</td><td>",regmodel_summary$adj.r.squared,"</td></tr>\n", + file = htmloutfile, append = TRUE); + + cat("</table>\n", file = htmloutfile, append = TRUE); + + cat( + "<font color='#ff0000'><h3>Regression and diagnostics plots</h3></font>\n", + file = htmloutfile, append = TRUE); + + outplot = paste(outdir,"/PE_TE_lm_1.png",sep="",collapse=""); + png(outplot, width = 10, height = 10, units = 'in',res=300); + # bitmap(outplot, "png16m"); + par(mfrow=c(1,1)); + plot(regmodel, 1, cex.lab=1.5); + dev.off(); + + outplot = paste(outdir,"/PE_TE_lm_2.png",sep="",collapse=""); + png(outplot,width = 10, height = 10, units = 'in', res=300); + # bitmap(outplot, "png16m"); + par(mfrow=c(1,1)); + plot(regmodel, 2, cex.lab=1.5); + dev.off(); + + outplot = paste(outdir,"/PE_TE_lm_5.png",sep="",collapse=""); + png(outplot, width = 10, height = 10, units = 'in',res=300); + # bitmap(outplot, "png16m"); + par(mfrow=c(1,1)); + plot(regmodel, 5, cex.lab=1.5); + dev.off(); + + cat('<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; ">', file = htmloutfile, append = TRUE); + + cat( + '<tr bgcolor="#7a0019"><th>', "<font color='#ffcc33'><h4>1) <u>Residuals vs Fitted plot</h4></font></u></th>\n", + '<th><font color=#ffcc33><h4>2) <u>Normal Q-Q plot of residuals</h4></font></u></th></tr>\n', + file = htmloutfile, append = TRUE); + + cat( + '<tr><td align=center><img src="PE_TE_lm_1.png" width=600 height=600></td><td align=center><img src="PE_TE_lm_2.png" width=600 height=600></td></tr>\n', + file = htmloutfile, append = TRUE); + + cat( + '<tr><td align=center>This plot checks for linear relationship assumptions.<br>If a horizontal line is observed without any distinct patterns, it indicates a linear relationship.</td>\n', + '<td align=center>This plot checks whether residuals are normally distributed or not.<br>It is good if the residuals points follow the straight dashed line i.e., do not deviate much from dashed line.</td></tr></table>\n', + file = htmloutfile, append = TRUE); + + + #@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ + # Residuals data + #@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ + res_all = regmodel$residuals; + res_mean = mean(res_all); + res_sd = sd(res_all); + res_diff = (res_all-res_mean); + res_zscore = res_diff/res_sd; + # res_outliers = res_all[which((res_zscore > 2)|(res_zscore < -2))] + + + tempind = which((res_zscore > 2)|(res_zscore < -2)); + res_PE_TE_data_no_outlier = PE_TE_data[-tempind,]; + res_PE_TE_data_no_outlier$residuals = res_all[-tempind]; + res_PE_TE_data_outlier = PE_TE_data[tempind,]; + res_PE_TE_data_outlier$residuals = res_all[tempind]; + + # Save the complete table for download (influential_observations) + temp_outlier_data = data.frame(res_PE_TE_data_outlier$PE_ID, res_PE_TE_data_outlier$TE_abundance, res_PE_TE_data_outlier$PE_abundance, res_PE_TE_data_outlier$residuals) + colnames(temp_outlier_data) = c("Gene", "Transcript abundance", "Protein abundance", "Residual value") + outdatafile = paste(outdir,"/PE_TE_outliers_residuals.txt", sep="", collapse=""); + write.table(temp_outlier_data, file=outdatafile, row.names=F, sep="\t", quote=F); + + + # Save the complete table for download (non influential_observations) + temp_all_data = data.frame(PE_TE_data$PE_ID, PE_TE_data$TE_abundance, PE_TE_data$PE_abundance, res_all) + colnames(temp_all_data) = c("Gene", "Transcript abundance", "Protein abundance", "Residual value") + outdatafile = paste(outdir,"/PE_TE_abundance_residuals.txt", sep="", collapse=""); + write.table(temp_all_data, file=outdatafile, row.names=F, sep="\t", quote=F); + + + cat('<br><h2 id="inf_obs"><font color=#ff0000>Outliers based on the residuals from regression analysis</font></h2>\n', + file = htmloutfile, append = TRUE); + cat('<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; ">\n', + '<tr bgcolor="#7a0019"><th colspan=2><font color=#ffcc33>Residuals from Regression</font></th></tr>\n', + '<tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Value</font></th></tr>\n', + file = htmloutfile, append = TRUE); + + cat("<tr><td>Mean Residual value</td><td>",res_mean,"</td></tr>\n", + "<tr><td>Standard deviation (Residuals)</td><td>",res_sd,"</td></tr>\n", + '<tr><td>Total outliers (Residual value > 2 standard deviation from the mean)</td><td>',length(tempind),' <font size=4>(<b><a href=PE_TE_outliers_residuals.txt target="_blank">Download these ',length(tempind),' data points with high residual values here</a></b>)</font></td>\n', + '<tr><td colspan=2 align=center><font size=4>(<b><a href=PE_TE_abundance_residuals.txt target="_blank">Download the complete residuals data here</a></b>)</font></td></td>\n', + "</table><br><br>\n", + file = htmloutfile, append = TRUE); + + #@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ + + + cat('<br><br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; ">', file = htmloutfile, append = TRUE); + + cat( + '<tr bgcolor="#7a0019"><th><font color=#ffcc33><h4>3) <u>Residuals vs Leverage plot</h4></font></u></th></tr>\n', + file = htmloutfile, append = TRUE); + + cat( + '<tr><td align=center><img src="PE_TE_lm_5.png" width=600 height=600></td></tr>\n', + file = htmloutfile, append = TRUE); + + cat( + '<tr><td align=center>This plot is useful to identify any influential cases, that is outliers or extreme values.<br>They might influence the regression results upon inclusion or exclusion from the analysis.</td></tr></table><br>\n', + file = htmloutfile, append = TRUE); + + + + #^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ + # Cook's Distance + #^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ + cat('<hr/><h2 id="inf_obs"><font color=#ff0000>INFLUENTIAL OBSERVATIONS</font></h2>\n', + file = htmloutfile, append = TRUE); + cat( + '<p><b>Cook\'s distance</b> computes the influence of each data point/observation on the predicted outcome. i.e. this measures how much the observation is influencing the fitted values.<br>In general use, those observations that have a <b>Cook\'s distance > than ', cookdist_upper_cutoff,' times the mean</b> may be classified as <b>influential.</b></p>\n', + file = htmloutfile, append = TRUE); + + cooksd <- cooks.distance(regmodel); + + outplot = paste(outdir,"/PE_TE_lm_cooksd.png",sep="",collapse=""); + png(outplot, width = 10, height = 10, units = 'in', res=300); + # bitmap(outplot, "png16m"); + par(mfrow=c(1,1)); + plot(cooksd, main="Influential Obs. by Cook\'s distance", ylab="Cook\'s distance", xlab="Observations", type="n") # plot cooks distance + sel_outlier=which(cooksd>=as.numeric(cookdist_upper_cutoff)*mean(cooksd, na.rm=T)) + sel_nonoutlier=which(cooksd<as.numeric(cookdist_upper_cutoff)*mean(cooksd, na.rm=T)) + points(sel_outlier, cooksd[sel_outlier],pch="*", cex=2, cex.lab=1.5, col="red") + points(sel_nonoutlier, cooksd[sel_nonoutlier],pch="*", cex=2, cex.lab=1.5, col="black") + abline(h = as.numeric(cookdist_upper_cutoff)*mean(cooksd, na.rm=T), col="red") # add cutoff line + #text(x=1:length(cooksd)+1, y=cooksd, labels=ifelse(cooksd>as.numeric(cookdist_upper_cutoff)*mean(cooksd, na.rm=T),names(cooksd),""), col="red", pos=2) # add labels + dev.off(); + + cat( + '<img src="PE_TE_lm_cooksd.png" width=800 height=800>', + '<br>In the above plot, observations above red line (',cookdist_upper_cutoff,' * mean Cook\'s distance) are influential. Genes that are outliers could be important. These observations influences the correlation values and regression coefficients<br><br>', + file = htmloutfile, append = TRUE); + + tempind = which(cooksd>as.numeric(cookdist_upper_cutoff)*mean(cooksd, na.rm=T)); + PE_TE_data_no_outlier = PE_TE_data[-tempind,]; + PE_TE_data_no_outlier$cooksd = cooksd[-tempind]; + PE_TE_data_outlier = PE_TE_data[tempind,]; + PE_TE_data_outlier$cooksd = cooksd[tempind]; + a = sort(PE_TE_data_outlier$cooksd, decreasing=T, index.return=T); + PE_TE_data_outlier_sorted = PE_TE_data_outlier[a$ix,]; + + cat( + '<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Value</font></th></tr>\n', + file = htmloutfile, append = TRUE); + + # Save the complete table for download (influential_observations) + temp_outlier_data = data.frame(PE_TE_data_outlier$PE_ID, PE_TE_data_outlier$TE_abundance, PE_TE_data_outlier$PE_abundance, PE_TE_data_outlier$cooksd) + colnames(temp_outlier_data) = c("Gene", "Transcript abundance", "Protein abundance", "Cook's distance") + outdatafile = paste(outdir,"/PE_TE_influential_observation.txt", sep="", collapse=""); + write.table(temp_outlier_data, file=outdatafile, row.names=F, sep="\t", quote=F); + + + # Save the complete table for download (non influential_observations) + temp_no_outlier_data = data.frame(PE_TE_data_no_outlier$PE_ID, PE_TE_data_no_outlier$TE_abundance, PE_TE_data_no_outlier$PE_abundance, PE_TE_data_no_outlier$cooksd) + colnames(temp_no_outlier_data) = c("Gene", "Transcript abundance", "Protein abundance", "Cook's distance") + outdatafile = paste(outdir,"/PE_TE_non_influential_observation.txt", sep="", collapse=""); + write.table(temp_no_outlier_data, file=outdatafile, row.names=F, sep="\t", quote=F); + + + cat("<tr><td>Mean Cook\'s distance</td><td>",mean(cooksd, na.rm=T),"</td></tr>\n", + "<tr><td>Total influential observations (Cook\'s distance > ",cookdist_upper_cutoff," * mean Cook\'s distance)</td><td>",length(tempind),"</td>\n", + + "<tr><td>Observations with Cook\'s distance < ",cookdist_upper_cutoff," * mean Cook\'s distance</td><td>",length(which(cooksd<as.numeric(cookdist_upper_cutoff)*mean(cooksd, na.rm=T))),"</td>\n", + "</table><br><br>\n", + file = htmloutfile, append = TRUE); + + + #@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ + # Scatter plot after removal of influential points + #@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ + outplot = paste(outdir,"/AbundancePlot_scatter_without_outliers.png",sep="",collapse=""); + min_lim = min(c(PE_TE_data$PE_abundance,PE_TE_data$TE_abundance)); + max_lim = max(c(PE_TE_data$PE_abundance,PE_TE_data$TE_abundance)); + png(outplot, width = 10, height = 10, units = 'in', res=300); + # bitmap(outplot,"png16m"); + g = ggplot(PE_TE_data_no_outlier, aes(x=TE_abundance, y=PE_abundance))+geom_point() + geom_smooth() + xlab("Transcript abundance log fold-change") + ylab("Protein abundance log fold-change") + xlim(min_lim,max_lim) + ylim(min_lim,max_lim); + suppressMessages(plot(g)); + dev.off(); + + cat('<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Scatterplot: Before removal</font></th><th><font color=#ffcc33>Scatterplot: After removal</font></th></tr>\n', file = htmloutfile, append = TRUE); + # Before + cat("<tr><td align=center><!--<font color='#ff0000'><h3>Scatter plot between Proteome and Transcriptome Abundance</h3></font>\n-->", '<img src="TE_PE_scatter.png" width=600 height=600></td>\n', file = htmloutfile, append = TRUE); + + # After + cat("<td align=center>\n", + '<img src="AbundancePlot_scatter_without_outliers.png" width=600 height=600></td></tr>\n', + file = htmloutfile, append = TRUE); + #@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ + + + cor_result_pearson = cor.test(PE_TE_data_no_outlier[,"TE_abundance"], PE_TE_data_no_outlier[,"PE_abundance"], method = "pearson"); + cor_result_spearman = cor.test(PE_TE_data_no_outlier[,"TE_abundance"], PE_TE_data_no_outlier[,"PE_abundance"], method = "spearman"); + cor_result_kendall = cor.test(PE_TE_data_no_outlier[,"TE_abundance"], PE_TE_data_no_outlier[,"PE_abundance"], method = "kendall"); + + cat('<tr><td>\n', file = htmloutfile, append=TRUE); + singlesample_cor(PE_TE_data, htmloutfile, append=TRUE); + cat('</td>\n', file = htmloutfile, append=TRUE); + + + cat('<td><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Method 1</font></th><th><font color=#ffcc33>Method 2</font></th><th><font color=#ffcc33>Method 3</font></th></tr>\n', + file = htmloutfile, append = TRUE); + + cat( + "<tr><td>Correlation method</td><td>",cor_result_pearson$method,"</td><td>",cor_result_spearman$method,"</td><td>",cor_result_kendall$method,"</td></tr>\n", + "<tr><td>Correlation coefficient</td><td>",cor_result_pearson$estimate,"</td><td>",cor_result_spearman$estimate,"</td><td>",cor_result_kendall$estimate,"</td></tr>\n", + file = htmloutfile, append = TRUE) + cat("</table></td></tr></table>\n", file = htmloutfile, append = TRUE) + + + + if(dim(PE_TE_data_outlier)[1]<10) + { + tab_n_row = dim(PE_TE_data_outlier)[1]; + }else{ + tab_n_row = 10; + } + + cat("<br><br><font size=5><b><a href='PE_TE_influential_observation.txt' target='_blank'>Download the complete list of influential observations</a></b></font> ", + "<font size=5><b><a href='PE_TE_non_influential_observation.txt' target='_blank'>Download the complete list (After removing influential points)</a></b></font><br>\n", + '<br><font color="brown"><h4>Top ',as.character(tab_n_row),' Influential observations (Cook\'s distance > ',cookdist_upper_cutoff,' * mean Cook\'s distance)</h4></font>\n', + file = htmloutfile, append = TRUE); + + cat('<table border=1 cellspacing=0 cellpadding=5> <tr bgcolor="#7a0019">\n', sep = "",file = htmloutfile, append = TRUE); + cat("<th><font color=#ffcc33>Gene</font></th><th><font color=#ffcc33>Protein Log Fold-Change</font></th><th><font color=#ffcc33>Transcript Log Fold-Change</font></th><th><font color=#ffcc33>Cook's Distance</font></th></tr>\n", + file = htmloutfile, append = TRUE); + + + for(i in 1:tab_n_row) + { + cat( + '<tr>','<td>',as.character(PE_TE_data_outlier_sorted[i,1]),'</td>\n', + '<td>',format(PE_TE_data_outlier_sorted[i,2], scientific=F),'</td>\n', + '<td>',PE_TE_data_outlier_sorted[i,4],'</td>\n', + '<td>',format(PE_TE_data_outlier_sorted[i,5], scientific=F),'</td></tr>\n', + file = htmloutfile, append = TRUE); + } + cat('</table><br><br>\n',file = htmloutfile, append = TRUE); + + +} + + + +#=============================================================================== +# Heatmap +#=============================================================================== +singlesample_heatmap=function(PE_TE_data, htmloutfile, hm_nclust){ + cat('<br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Heatmap of PE and TE abundance values (Hierarchical clustering)</font></th><th><font color=#ffcc33>Number of clusters to extract: ',hm_nclust,'</font></th></tr>\n', + file = htmloutfile, append = TRUE); + + hc=hclust(dist(as.matrix(PE_TE_data[,c("PE_abundance","TE_abundance")]))) + hm_cluster = cutree(hc,k=hm_nclust); + + outplot = paste(outdir,"/PE_TE_heatmap.png",sep="",collapse=""); + png(outplot, width = 10, height = 10, units = 'in', res=300); + # bitmap(outplot, "png16m"); + par(mfrow=c(1,1)); + hmap = heatmap.2(as.matrix(PE_TE_data[,c("PE_abundance","TE_abundance")]), trace="none", cexCol=1, col=greenred(100),Colv=F, labCol=c("Proteins","Transcripts"), scale="col", hclustfun = hclust, distfun = dist); + dev.off(); + + cat('<tr><td align=center colspan="2"><img src="PE_TE_heatmap.png" width=800 height=800></td></tr>\n', + file = htmloutfile, append = TRUE); + + + temp_PE_TE_data = data.frame(PE_TE_data$PE_ID, PE_TE_data$TE_abundance, PE_TE_data$PE_abundance, hm_cluster); + colnames(temp_PE_TE_data) = c("Gene", "Transcript abundance", "Protein abundance", "Cluster (Hierarchical clustering)") + tempoutfile = paste(outdir,"/PE_TE_hc_clusterpoints.txt",sep="",collapse=""); + write.table(temp_PE_TE_data, file=tempoutfile, row.names=F, quote=F, sep="\t", eol="\n") + + + cat('<tr><td colspan="2" align=center><font size=5><a href="PE_TE_hc_clusterpoints.txt" target="_blank"><b>Download the hierarchical cluster list</b></a></font></td></tr></table>\n', + file = htmloutfile, append = TRUE); +} + + +#=============================================================================== +# K-means clustering +#=============================================================================== +singlesample_kmeans=function(PE_TE_data, htmloutfile, nclust){ + PE_TE_data_kdata = PE_TE_data; + k1 = kmeans(PE_TE_data_kdata[,c("PE_abundance","TE_abundance")], nclust); + outplot = paste(outdir,"/PE_TE_kmeans.png",sep="",collapse=""); + png(outplot, width = 10, height = 10, units = 'in', res=300); + # bitmap(outplot, "png16m"); + par(mfrow=c(1,1)); + scatter.smooth(PE_TE_data_kdata[,"TE_abundance"], PE_TE_data_kdata[,"PE_abundance"], xlab="Transcript Abundance", ylab="Protein Abundance", cex.lab=1.5); + legend(1, 95, legend=c("Cluster 1", "Line 2"), col="red", lty=1:1, cex=0.8) + legend(1, 95, legend="Cluster 2", col="green", lty=1:1, cex=0.8) + + + ind=which(k1$cluster==1); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="red", pch=16); + ind=which(k1$cluster==2); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="green", pch=16); + ind=which(k1$cluster==3); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="blue", pch=16); + ind=which(k1$cluster==4); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="cyan", pch=16); + ind=which(k1$cluster==5); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="black", pch=16); + ind=which(k1$cluster==6); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="brown", pch=16); + ind=which(k1$cluster==7); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="gold", pch=16); + ind=which(k1$cluster==8); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="thistle", pch=16); + ind=which(k1$cluster==9); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="yellow", pch=16); + ind=which(k1$cluster==10); + points(PE_TE_data_kdata[ind,"TE_abundance"], PE_TE_data_kdata[ind,"PE_abundance"], col="orange", pch=16); + dev.off(); + + cat('<br><br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>K-mean clustering</font></th><th><font color=#ffcc33>Number of clusters: ',nclust,'</font></th></tr>\n', + file = htmloutfile, append = TRUE); + + tempind = order(k1$cluster); + tempoutfile = paste(outdir,"/PE_TE_kmeans_clusterpoints.txt",sep="",collapse=""); + write.table(data.frame(PE_TE_data_kdata[tempind, ], Cluster=k1$cluster[tempind]), file=tempoutfile, row.names=F, quote=F, sep="\t", eol="\n") + + + cat('<tr><td colspan="2" align=center><img src="PE_TE_kmeans.png" width=800 height=800></td></tr>\n', + file = htmloutfile, append = TRUE); + cat('<tr><td colspan="2" align=center><font size=5><a href="PE_TE_kmeans_clusterpoints.txt" target="_blank"><b>Download the cluster list</b></a></font></td></tr></table><br><hr/>\n', + file = htmloutfile, append = TRUE); + +} + +#=============================================================================== +# scatter plot +#=============================================================================== +singlesample_scatter = function(PE_TE_data, outfile) +{ + min_lim = min(c(PE_TE_data$PE_abundance,PE_TE_data$TE_abundance)); + max_lim = max(c(PE_TE_data$PE_abundance,PE_TE_data$TE_abundance)); + png(outfile, width = 10, height = 10, units = 'in', res=300); + # bitmap(outfile, "png16m"); + g = ggplot(PE_TE_data, aes(x=TE_abundance, y=PE_abundance))+geom_point() + geom_smooth() + xlab("Transcript abundance log fold-change") + ylab("Protein abundance log fold-change") + xlim(min_lim,max_lim) + ylim(min_lim,max_lim); + suppressMessages(plot(g)); + # plot(g); + dev.off(); +} + +#=============================================================================== +# Correlation table +#=============================================================================== +singlesample_cor = function(PE_TE_data, htmloutfile, append=TRUE) +{ + cor_result_pearson = cor.test(PE_TE_data$TE_abundance, PE_TE_data$PE_abundance, method = "pearson"); + cor_result_spearman = cor.test(PE_TE_data$TE_abundance, PE_TE_data$PE_abundance, method = "spearman"); + cor_result_kendall = cor.test(PE_TE_data$TE_abundance, PE_TE_data$PE_abundance, method = "kendall"); + + cat( + '<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Method 1</font></th><th><font color=#ffcc33>Method 2</font></th><th><font color=#ffcc33>Method 3</font></th></tr>\n', + file = htmloutfile, append = TRUE); + + cat( + "<tr><td>Correlation method</td><td>",cor_result_pearson$method,"</td><td>",cor_result_spearman$method,"</td><td>",cor_result_kendall$method,"</td></tr>\n", + "<tr><td>Correlation coefficient</td><td>",cor_result_pearson$estimate,"</td><td>",cor_result_spearman$estimate,"</td><td>",cor_result_kendall$estimate,"</td></tr>\n", + file = htmloutfile, append = TRUE) + cat("</table>\n", file = htmloutfile, append = TRUE); + +} + +#=============================================================================== +# Boxplot +#=============================================================================== +multisample_boxplot = function(df, sampleinfo_df, outfile, fill_leg, user_xlab, user_ylab) +{ + tempdf = df[,-1, drop=FALSE]; + tempdf = t(tempdf) %>% as.data.frame(); + tempdf[is.na(tempdf)] = 0; + tempdf$Sample = rownames(tempdf); + tempdf1 = melt(tempdf, id.vars = "Sample"); + tempdf1$Group = sampleinfo_df[tempdf1$Sample,2]; + png(outplot, width = 6, height = 6, units = 'in', res=300); + # bitmap(outplot, "png16m"); + if(fill_leg=="Yes") + { + g = ggplot(tempdf1, aes(x=Sample, y=value, fill=Group)) + geom_boxplot() + labs(x=user_xlab) + labs(y=user_ylab) + }else{ + if(fill_leg=="No") + { + tempdf1$Group = c("case", "control") + g = ggplot(tempdf1, aes(x=Sample, y=value, fill=Group)) + geom_boxplot() + labs(x=user_xlab) + labs(y=user_ylab) + } + } + plot(g); + dev.off(); +} + + +#=============================================================================== +# Mean or Median of Replicates +#=============================================================================== + +mergeReplicates = function(TE_df,PE_df, sampleinfo_df, method) +{ +grps = unique(sampleinfo_df[,2]); + +TE_df_merged <<- sapply(grps, function(x){ + tempsample = sampleinfo_df[which(sampleinfo_df$Group==x),1] + if(length(tempsample)!=1){ + apply(TE_df[,tempsample],1,method); + }else{ + return(TE_df[,tempsample]); + } +}); +TE_df_merged <<- data.frame(as.character(TE_df[,1]), TE_df_merged); +colnames(TE_df_merged) = c(colnames(TE_df)[1], grps); + +PE_df_merged <<- sapply(grps, function(x){ + tempsample = sampleinfo_df[which(sampleinfo_df$Group==x),1] + if(length(tempsample)!=1){ + apply(PE_df[,tempsample],1,method); + }else{ + return(PE_df[,tempsample]); + } +}); + +PE_df_merged <<- data.frame(as.character(PE_df[,1]), PE_df_merged); +colnames(PE_df_merged) = c(colnames(PE_df)[1], grps); + +#sampleinfo_df_merged = data.frame(Sample = grps, Group = grps, stringsAsFactors = F); +sampleinfo_df_merged = data.frame(Sample = grps, Group = "Group", stringsAsFactors = F); + +return(list(TE_df_merged = TE_df_merged, PE_df_merged = PE_df_merged, sampleinfo_df_merged = sampleinfo_df_merged)); +} + +#=============================================================================== +# (T-Test or Wilcoxon ranksum test) and Volcano Plot +#=============================================================================== + +perform_Test_Volcano = function(TE_df_data,PE_df_data,TE_df_logfold, PE_df_logfold,sampleinfo_df, method, correction_method,volc_with) +{ + +PE_colnames = colnames(PE_df_data); +control_sample = sampleinfo_df[which(sampleinfo_df$Group=="control"),1]; +control_ind <<- sapply(control_sample, function(x){temp_ind = which(PE_colnames==x); as.numeric(temp_ind)}); +condition_sample = sampleinfo_df[which(sampleinfo_df$Group=="case"),1]; +condition_ind <<- sapply(condition_sample, function(x){temp_ind = which(PE_colnames==x); as.numeric(temp_ind)}); + +if(method=="mean"){ + #PE_pval = apply(PE_df_data[2:length(colnames(PE_df_data))],1,function(x) t.test(x[condition_ind-1], x[control_ind-1])$p.value); + PE_pval = apply(PE_df_data[2:length(colnames(PE_df_data))],1,function(x) {obj<-try(t.test(x[condition_ind-1], x[control_ind-1]),silent=TRUE); if(is(obj, "try-error")){return(NA)}else{return(obj$p.value)}}) +}else{ +if(method=="median"){ + PE_pval = apply(PE_df_data[2:length(colnames(PE_df_data))],1,function(x) {obj<-try(wilcox.test(x[condition_ind-1], x[control_ind-1]),silent=TRUE); if(is(obj, "try-error")){return(NA)}else{return(obj$p.value)}}) + # PE_pval = apply(PE_df_data[2:length(colnames(PE_df_data))],1,function(x) wilcox.test(x[condition_ind-1], x[control_ind-1])$p.value); + } +} +PE_adj_pval = p.adjust(PE_pval, method = correction_method, n = length(PE_pval)) + + +TE_colnames = colnames(TE_df_data); +control_sample = sampleinfo_df[which(sampleinfo_df$Group=="control"),1]; +control_ind <<- sapply(control_sample, function(x){temp_ind = which(TE_colnames==x); as.numeric(temp_ind)}); +condition_sample = sampleinfo_df[which(sampleinfo_df$Group=="case"),1]; +condition_ind <<- sapply(condition_sample, function(x){temp_ind = which(TE_colnames==x); as.numeric(temp_ind)}); + +if(method=="mean"){ + # TE_pval = apply(TE_df_data[2:length(colnames(TE_df_data))],1,function(x) t.test(x[condition_ind-1], x[control_ind-1])$p.value); + TE_pval = apply(TE_df_data[2:length(colnames(TE_df_data))],1,function(x) {obj<-try(t.test(x[condition_ind-1], x[control_ind-1]),silent=TRUE); if(is(obj, "try-error")){return(NA)}else{return(obj$p.value)}}) +}else{ + if(method=="median"){ + TE_pval = apply(TE_df_data[2:length(colnames(TE_df_data))],1,function(x) {obj<-try(wilcox.test(x[condition_ind-1], x[control_ind-1]),silent=TRUE); if(is(obj, "try-error")){return(NA)}else{return(obj$p.value)}}) + # TE_pval = apply(TE_df_data[2:length(colnames(TE_df_data))],1,function(x) wilcox.test(x[condition_ind-1], x[control_ind-1])$p.value); + } +} +TE_adj_pval = p.adjust(TE_pval, method = correction_method, n = length(TE_pval)) + + +PE_TE_logfold_pval = data.frame(TE_df_logfold$Gene, TE_df_logfold$LogFold, TE_pval, TE_adj_pval, PE_df_logfold$LogFold, PE_pval, PE_adj_pval); +colnames(PE_TE_logfold_pval) = c("Gene", "Transcript log fold-change", "p-value (transcript)", "adj p-value (transcript)", "Protein log fold-change", "p-value (protein)", "adj p-value (protein)"); +outdatafile = paste(outdir,"/PE_TE_logfold_pval.txt", sep="", collapse=""); +write.table(PE_TE_logfold_pval, file=outdatafile, row.names=F, sep="\t", quote=F); +cat("<br><br><font size=5><b><a href='PE_TE_logfold_pval.txt' target='_blank'>Download the complete fold change data here</a></b></font><br>\n", + file = htmloutfile, append = TRUE); + + if(length(condition_ind)!=1) + { + # Volcano Plot + + if(volc_with=="adj_pval") + { + PE_pval = PE_adj_pval + TE_pval = TE_adj_pval + volc_ylab = "-log10 Adjusted p-value"; + }else{ + if(volc_with=="pval") + { + volc_ylab = "-log10 p-value"; + } + } + outplot = paste(outdir,"/PE_volcano.png",sep="",collapse=""); + png(outplot, width = 10, height = 10, units = 'in', res=300); + # bitmap(outplot, "png16m"); + par(mfrow=c(1,1)); + + plot(PE_df_logfold$LogFold, -log10(PE_pval), + xlab="log2 fold change", ylab=volc_ylab, + type="n") + sel <- which((PE_df_logfold$LogFold<=log(2,base=2))&(PE_df_logfold$LogFold>=log(0.5, base=2))) # or whatever you want to use + points(PE_df_logfold[sel,"LogFold"], -log10(PE_pval[sel]),col="black") + #sel <- which((PE_df_logfold$LogFold>log(2,base=2))&(PE_df_logfold$LogFold<log(0.5,base=2))) # or whatever you want to use + sel <- which((PE_df_logfold$LogFold>log(2,base=2))|(PE_df_logfold$LogFold<log(0.5, base=2))) + sel1 <- which(PE_pval<=0.05) + sel=intersect(sel,sel1) + points(PE_df_logfold[sel,"LogFold"], -log10(PE_pval[sel]),col="red") + sel <- which((PE_df_logfold$LogFold>log(2,base=2))|(PE_df_logfold$LogFold<log(0.5, base=2))) + sel1 <- which(PE_pval>0.05) + sel=intersect(sel,sel1) + points(PE_df_logfold[sel,"LogFold"], -log10(PE_pval[sel]),col="blue") + abline(h = -log(0.05,base=10), col="red", lty=2) + abline(v = log(2,base=2), col="red", lty=2) + abline(v = log(0.5,base=2), col="red", lty=2) + dev.off(); + + + + outplot = paste(outdir,"/TE_volcano.png",sep="",collapse=""); + png(outplot, width = 10, height = 10, units = 'in', res=300); + # bitmap(outplot, "png16m"); + par(mfrow=c(1,1)); + + plot(TE_df_logfold$LogFold, -log10(TE_pval), + xlab="log2 fold change", ylab=volc_ylab, + type="n") + sel <- which((TE_df_logfold$LogFold<=log(2,base=2))&(TE_df_logfold$LogFold>=log(0.5, base=2))) # or whatever you want to use + points(TE_df_logfold[sel,"LogFold"], -log10(TE_pval[sel]),col="black") + #sel <- which((TE_df_logfold$LogFold>log(2,base=2))&(TE_df_logfold$LogFold<log(0.5,base=2))) # or whatever you want to use + sel <- which((TE_df_logfold$LogFold>log(2,base=2))|(TE_df_logfold$LogFold<log(0.5, base=2))) + sel1 <- which(TE_pval<=0.05) + sel=intersect(sel,sel1) + points(TE_df_logfold[sel,"LogFold"], -log10(TE_pval[sel]),col="red") + sel <- which((TE_df_logfold$LogFold>log(2,base=2))|(TE_df_logfold$LogFold<log(0.5, base=2))) + sel1 <- which(TE_pval>0.05) + sel=intersect(sel,sel1) + points(TE_df_logfold[sel,"LogFold"], -log10(TE_pval[sel]),col="blue") + abline(h = -log(0.05,base=10), col="red", lty=2) + abline(v = log(2,base=2), col="red", lty=2) + abline(v = log(0.5,base=2), col="red", lty=2) + dev.off(); + + + + cat('<br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Transcript Fold-Change</font></th><th><font color=#ffcc33>Protein Fold-Change</font></th></tr>\n', file = htmloutfile, append = TRUE); + cat("<tr><td align=center>", '<img src="TE_volcano.png" width=600 height=600></td>\n', file = htmloutfile, append = TRUE); + cat("<td align=center>", + '<img src="PE_volcano.png" width=600 height=600></td></tr></table><br>\n', + file = htmloutfile, append = TRUE); + }else{ + cat('<br><br><b><font color=red>!!! No replicates found. Cannot perform test to check significance of differential expression. Thus, no Volcano plot generated !!!</font></b><br><br>', + file = htmloutfile, append = TRUE); + } + +} + + +#*************************************************************************************************************************************** +# Functions: End +#*************************************************************************************************************************************** + + + + +#=============================================================================== +# Arguments +#=============================================================================== +noargs = 12; +args = commandArgs(trailingOnly = TRUE); +if(length(args) != noargs) +{ + stop(paste("Please check usage. Number of arguments is not equal to ",noargs,sep="",collapse="")); +} + +mode = args[1]; # "multiple" or "logfold" +method = args[2]; # "mean" or "median" +sampleinfo_file = args[3]; +proteome_file = args[4]; +transcriptome_file = args[5]; +correction_method = args[6]; +cookdist_upper_cutoff = args[7]; +numCluster = args[8]; +hm_nclust = args[9]; +volc_with = args[10]; + +htmloutfile = args[11]; # html output file +outdir = args[12]; # html supporting files + + +#=============================================================================== +# Check for file existance +#=============================================================================== +if(! file.exists(proteome_file)) +{ + stop(paste("Proteome Data file does not exists. Path given: ",proteome_file,sep="",collapse="")); +} +if(! file.exists(transcriptome_file)) +{ + stop(paste("Transcriptome Data file does not exists. Path given: ",transcriptome_file,sep="",collapse="")); +} + +#=============================================================================== +# Load library +#=============================================================================== +options(warn=-1); + +suppressPackageStartupMessages(library(dplyr)); +suppressPackageStartupMessages(library(data.table)); +suppressPackageStartupMessages(library(gplots)); +suppressPackageStartupMessages(library(ggplot2)); +suppressPackageStartupMessages(library(ggfortify)); + +#=============================================================================== +# Select mode and parse experiment design file +#=============================================================================== +if(mode=="multiple") +{ + expDesign = fread(sampleinfo_file, header = FALSE, stringsAsFactors = FALSE, sep="\t") %>% data.frame(); + expDesign_cc = expDesign[1:2,]; + + sampleinfo_df = expDesign[3:nrow(expDesign),]; + rownames(sampleinfo_df)=1:nrow(sampleinfo_df); + colnames(sampleinfo_df) = c("Sample","Group"); + + condition_cols = sampleinfo_df[which(sampleinfo_df[,2]==expDesign_cc[which(expDesign_cc[,1]=="case"),2]),1]; + condition_g_name = "case"; + control_cols = sampleinfo_df[which(sampleinfo_df[,2]==expDesign_cc[which(expDesign_cc[,1]=="control"),2]),1]; + control_g_name = "control"; + sampleinfo_df[which(sampleinfo_df[,2]==expDesign_cc[which(expDesign_cc[,1]=="case"),2]),2] = "case"; + sampleinfo_df[which(sampleinfo_df[,2]==expDesign_cc[which(expDesign_cc[,1]=="control"),2]),2] = "control"; + sampleinfo_df_orig = sampleinfo_df; +} + +if(mode=="logfold") +{ + sampleinfo_df = data.frame("Sample"= c("LogFold"), "Group"=c("Fold_Change")) +} + +#=============================================================================== +# Parse Transcriptome data +#=============================================================================== +TE_df_orig = fread(transcriptome_file, sep="\t", stringsAsFactor=F, header=T) %>% data.frame(); +if(mode=="multiple") +{ + TE_df = TE_df_orig[,c(colnames(TE_df_orig)[1],condition_cols,control_cols)]; +} +if(mode=="logfold") +{ + TE_df = TE_df_orig; + colnames(TE_df) = c("Genes", "LogFold"); +} +#=============================================================================== +# Parse Proteome data +#=============================================================================== +PE_df_orig = fread(proteome_file, sep="\t", stringsAsFactor=F, header=T) %>% data.frame(); +if(mode=="multiple") +{ + PE_df = PE_df_orig[,c(colnames(PE_df_orig)[1],condition_cols,control_cols)]; +} +if(mode=="logfold") +{ + PE_df = PE_df_orig; + colnames(PE_df) = c("Genes", "LogFold"); +} + +#============================================================================================================= +# Create directory structures and then set the working directory to output directory +#============================================================================================================= +if(! file.exists(outdir)) +{ + dir.create(outdir); +} +#=============================================================================== +# Write initial data summary in html outfile +#=============================================================================== + cat("<html><head></head><body>\n", file = htmloutfile); + + cat("<h1><u>QuanTP: Association between abundance ratios of transcript and protein</u></h1><hr/>\n", + "<font><h3>Input data summary</h3></font>\n", + "<ul>\n", + "<li>Abbreviations used: PE (Proteome data) and TE (Transcriptome data)","</li><br>\n", + "<li>Input Proteome data dimension (Row Column): ", dim(PE_df)[1]," x ", dim(PE_df)[2],"</li>\n", + "<li>Input Transcriptome data dimension (Row Column): ", dim(TE_df)[1]," x ", dim(TE_df)[2],"</li></ul><hr/>\n", + file = htmloutfile, append = TRUE); + + cat("<h3 id=table_of_content>Table of Contents:</h3>\n", + "<ul>\n", + "<li><a href=#sample_dist>Sample distribution</a></li>\n", + "<li><a href=#corr_data>Correlation</a></li>\n", + "<li><a href=#regression_data>Regression analysis</a></li>\n", + "<li><a href=#inf_obs>Influential observations</a></li>\n", + "<li><a href=#cluster_data>Cluster analysis</a></li></ul><hr/>\n", + file = htmloutfile, append = TRUE); +#=============================================================================== +# Find common samples +#=============================================================================== +common_samples = intersect(sampleinfo_df[,1], colnames(TE_df)[-1]) %>% intersect(., colnames(PE_df)[-1]); + +if(length(common_samples)==0) +{ + stop("No common samples found "); + cat("<b>Please check your experiment design file. Sample names (column names) in the Transcriptome and the Proteome data do not match. </b>\n",file = htmloutfile, append = TRUE); +} + +#=============================================================================== +# Create subsets based on common samples +#=============================================================================== +TE_df = select(TE_df, 1, common_samples); +PE_df = select(PE_df, 1, common_samples); +sampleinfo_df = filter(sampleinfo_df, Sample %in% common_samples); +rownames(sampleinfo_df) = sampleinfo_df[,1]; + +#=============================================================================== +# Check for number of rows similarity +#=============================================================================== +if(nrow(TE_df) != nrow(PE_df)) +{ + stop("Number of rows in Transcriptome and Proteome data are not same i.e. they are not paired"); + cat("<b>The correlation analysis expects paired TE and PE data i.e. (i)th gene/transcript of TE file should correspond to (i)th protein of PE file. In the current input provided there is mismatch in terms of number of rows of TE and PE file. Please make sure you provide paired data.</b>\n",file = htmloutfile, append = TRUE); +} + +#=============================================================================== +# Number of groups +#=============================================================================== +ngrps = unique(sampleinfo_df[,2]) %>% length(); +grps = unique(sampleinfo_df[,2]); +names(grps) = grps; + +#=============================================================================== +# Change column1 name +#=============================================================================== +colnames(TE_df)[1] = "Gene"; +colnames(PE_df)[1] = "Protein"; + +#=============================================================================== +# Treat missing values +#=============================================================================== +TE_nacount = sum(is.na(TE_df)); +PE_nacount = sum(is.na(PE_df)); + +TE_df[is.na(TE_df)] = 0; +PE_df[is.na(PE_df)] = 0; + + +#=============================================================================== +# Decide based on analysis mode +#=============================================================================== +if(mode=="logfold") +{ + cat('<h2 id="sample_dist"><font color=#ff0000>SAMPLE DISTRIBUTION</font></h2>\n', + file = htmloutfile, append = TRUE); + + # TE Boxplot + outplot = paste(outdir,"/Box_TE.png",sep="",collape=""); + cat('<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; ">\n', + '<tr bgcolor="#7a0019"><th><font color=#ffcc33>Boxplot: Transcriptome data</font></th><th><font color=#ffcc33>Boxplot: Proteome data</font></th></tr>\n', + "<tr><td align=center>", '<img src="Box_TE.png" width=500 height=500></td>\n', file = htmloutfile, append = TRUE); + multisample_boxplot(TE_df, sampleinfo_df, outplot, "Yes", "Samples", "Transcript Abundance data"); + + # PE Boxplot + outplot = paste(outdir,"/Box_PE.png",sep="",collape=""); + cat("<td align=center>", '<img src="Box_PE.png" width=500 height=500></td></tr></table>\n', file = htmloutfile, append = TRUE); + multisample_boxplot(PE_df, sampleinfo_df, outplot, "Yes", "Samples", "Protein Abundance data"); + + cat('<hr/><h2 id="corr_data"><font color=#ff0000>CORRELATION</font></h2>\n', + file = htmloutfile, append = TRUE); + + # TE PE scatter + outplot = paste(outdir,"/TE_PE_scatter.png",sep="",collape=""); + cat('<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Scatter plot between Proteome and Transcriptome Abundance</font></th></tr>\n', file = htmloutfile, append = TRUE); + cat("<tr><td align=center>", '<img src="TE_PE_scatter.png" width=800 height=800></td></tr>\n', file = htmloutfile, append = TRUE); + PE_TE_data = data.frame(PE_df, TE_df); + colnames(PE_TE_data) = c("PE_ID","PE_abundance","TE_ID","TE_abundance"); + singlesample_scatter(PE_TE_data, outplot); + + # TE PE Cor + cat("<tr><td align=center>", file = htmloutfile, append = TRUE); + singlesample_cor(PE_TE_data, htmloutfile, append=TRUE); + cat('<font color="red">*Note that <u>correlation</u> is <u>sensitive to outliers</u> in the data. So it is important to analyze outliers/influential observations in the data.<br> Below we use <u>Cook\'s distance based approach</u> to identify such influential observations.</font>\n', + file = htmloutfile, append = TRUE); + cat('</td></table>', + file = htmloutfile, append = TRUE); + + cat('<hr/><h2 id="regression_data"><font color=#ff0000>REGRESSION ANALYSIS</font></h2>\n', + file = htmloutfile, append = TRUE); + + # TE PE Regression + singlesample_regression(PE_TE_data,htmloutfile, append=TRUE); + + cat('<hr/><h2 id="cluster_data"><font color=#ff0000>CLUSTER ANALYSIS</font></h2>\n', + file = htmloutfile, append = TRUE); + + # TE PE Heatmap + singlesample_heatmap(PE_TE_data, htmloutfile, hm_nclust); + + + # TE PE Clustering (kmeans) + singlesample_kmeans(PE_TE_data, htmloutfile, nclust=as.numeric(numCluster)) + +}else{ + if(mode=="multiple") + { + cat('<h2 id="sample_dist"><font color=#ff0000>SAMPLE DISTRIBUTION</font></h2>\n', + file = htmloutfile, append = TRUE); + + # TE Boxplot + outplot = paste(outdir,"/Box_TE_all_rep.png",sep="",collape=""); + cat('<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; ">\n', + '<tr bgcolor="#7a0019"><th><font color=#ffcc33>Boxplot: Transcriptome data</font></th><th><font color=#ffcc33>Boxplot: Proteome data</font></th></tr>\n', + "<tr><td align=center>", '<img src="Box_TE_all_rep.png" width=500 height=500></td>\n', file = htmloutfile, append = TRUE); + temp_df_te_data = data.frame(TE_df[,1], log(TE_df[,2:length(TE_df)])); + colnames(temp_df_te_data) = colnames(TE_df); + multisample_boxplot(temp_df_te_data, sampleinfo_df, outplot, "Yes", "Samples", "Transcript Abundance (log)"); + + # PE Boxplot + outplot = paste(outdir,"/Box_PE_all_rep.png",sep="",collape=""); + cat("<td align=center>", '<img src="Box_PE_all_rep.png" width=500 height=500></td></tr></table>\n', file = htmloutfile, append = TRUE); + temp_df_pe_data = data.frame(PE_df[,1], log(PE_df[,2:length(PE_df)])); + colnames(temp_df_pe_data) = colnames(PE_df); + multisample_boxplot(temp_df_pe_data, sampleinfo_df, outplot, "Yes", "Samples", "Protein Abundance (log)"); + + # Calc TE PCA + outplot = paste(outdir,"/PCA_TE_all_rep.png",sep="",collape=""); + multisample_PCA(TE_df, sampleinfo_df, outplot); + + # Calc PE PCA + outplot = paste(outdir,"/PCA_PE_all_rep.png",sep="",collape=""); + multisample_PCA(PE_df, sampleinfo_df, outplot); + + + # Replicate mode + templist = mergeReplicates(TE_df,PE_df, sampleinfo_df, method); + TE_df = templist$TE_df_merged; + PE_df = templist$PE_df_merged; + sampleinfo_df = templist$sampleinfo_df_merged; + rownames(sampleinfo_df) = sampleinfo_df[,1]; + + # TE Boxplot + outplot = paste(outdir,"/Box_TE_rep.png",sep="",collape=""); + cat('<br><font color="#ff0000"><h3>Sample wise distribution (Box plot) after using ',method,' on replicates </h3></font><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Boxplot: Transcriptome data</font></th><th><font color=#ffcc33>Boxplot: Proteome data</font></th></tr>\n', + "<tr><td align=center>", '<img src="Box_TE_rep.png" width=500 height=500></td>\n', file = htmloutfile, append = TRUE); + temp_df_te_data = data.frame(TE_df[,1], log(TE_df[,2:length(TE_df)])); + colnames(temp_df_te_data) = colnames(TE_df); + multisample_boxplot(temp_df_te_data, sampleinfo_df, outplot, "No", "Sample Groups", "Mean Transcript Abundance (log)"); + + # PE Boxplot + outplot = paste(outdir,"/Box_PE_rep.png",sep="",collape=""); + cat("<td align=center>", '<img src="Box_PE_rep.png" width=500 height=500></td></tr></table>\n', file = htmloutfile, append = TRUE); + temp_df_pe_data = data.frame(PE_df[,1], log(PE_df[,2:length(PE_df)])); + colnames(temp_df_pe_data) = colnames(PE_df); + multisample_boxplot(temp_df_pe_data, sampleinfo_df, outplot, "No", "Sample Groups", "Mean Protein Abundance (log)"); + + #=============================================================================== + # Calculating log fold change and running the "single" code part + #=============================================================================== + + TE_df = data.frame("Genes"=TE_df[,1], "LogFold"=apply(TE_df[,c(which(colnames(TE_df)==condition_g_name),which(colnames(TE_df)==control_g_name))],1,function(x) log(x[1]/x[2],base=2))); + PE_df = data.frame("Genes"=PE_df[,1], "LogFold"=apply(PE_df[,c(which(colnames(PE_df)==condition_g_name),which(colnames(PE_df)==control_g_name))],1,function(x) log(x[1]/x[2],base=2))); + + #=============================================================================== + # Treat missing values + #=============================================================================== + + TE_df[is.infinite(TE_df[,2]),2] = NA; + PE_df[is.infinite(PE_df[,2]),2] = NA; + TE_df[is.na(TE_df)] = 0; + PE_df[is.na(PE_df)] = 0; + + sampleinfo_df = data.frame("Sample"= c("LogFold"), "Group"=c("Fold_Change")) + #=============================================================================== + # Find common samples + #=============================================================================== + + common_samples = intersect(sampleinfo_df[,1], colnames(TE_df)[-1]) %>% intersect(., colnames(PE_df)[-1]); + TE_df = select(TE_df, 1, common_samples); + PE_df = select(PE_df, 1, common_samples); + sampleinfo_df = filter(sampleinfo_df, Sample %in% common_samples); + rownames(sampleinfo_df) = sampleinfo_df[,1]; + + # TE Boxplot + outplot = paste(outdir,"/Box_TE.png",sep="",collape=""); + cat('<br><font color="#ff0000"><h3>Distribution (Box plot) of log fold change </h3></font>', file = htmloutfile, append = TRUE); + cat('<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Boxplot: Transcriptome data</font></th><th><font color=#ffcc33>Boxplot: Proteome data</font></th></tr>\n', + "<tr><td align=center>", '<img src="Box_TE.png" width=500 height=500></td>\n', file = htmloutfile, append = TRUE); + multisample_boxplot(TE_df, sampleinfo_df, outplot, "Yes", "Sample (log2(case/control))", "Transcript Abundance fold-change (log2)"); + + # PE Boxplot + outplot = paste(outdir,"/Box_PE.png",sep="",collape=""); + cat("<td align=center>", '<img src="Box_PE.png" width=500 height=500></td></tr></table>\n', file = htmloutfile, append = TRUE); + multisample_boxplot(PE_df, sampleinfo_df, outplot, "Yes", "Sample (log2(case/control))", "Protein Abundance fold-change(log2)"); + + + # Log Fold Data + perform_Test_Volcano(TE_df_orig,PE_df_orig,TE_df, PE_df,sampleinfo_df_orig,method,correction_method,volc_with) + + + + # Print PCA + + cat('<br><br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>PCA plot: Transcriptome data</font></th><th><font color=#ffcc33>PCA plot: Proteome data</font></th></tr>\n', + "<tr><td align=center>", '<img src="PCA_TE_all_rep.png" width=500 height=500></td>\n', + "<td align=center>", '<img src="PCA_PE_all_rep.png" width=500 height=500></td></tr></table>\n', + file = htmloutfile, append = TRUE); + + + + cat('<hr/><h2 id="corr_data"><font color=#ff0000>CORRELATION</font></h2>\n', + file = htmloutfile, append = TRUE); + + # TE PE scatter + outplot = paste(outdir,"/TE_PE_scatter.png",sep="",collape=""); + cat('<br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Scatter plot between Proteome and Transcriptome Abundance</font></th></tr>\n', file = htmloutfile, append = TRUE); + cat("<tr><td align=center>", '<img src="TE_PE_scatter.png" width=800 height=800></td>\n', file = htmloutfile, append = TRUE); + PE_TE_data = data.frame(PE_df, TE_df); + colnames(PE_TE_data) = c("PE_ID","PE_abundance","TE_ID","TE_abundance"); + singlesample_scatter(PE_TE_data, outplot); + + # TE PE Cor + cat("<tr><td align=center>\n", file = htmloutfile, append = TRUE); + singlesample_cor(PE_TE_data, htmloutfile, append=TRUE); + cat('<font color="red">*Note that <u>correlation</u> is <u>sensitive to outliers</u> in the data. So it is important to analyze outliers/influential observations in the data.<br> Below we use <u>Cook\'s distance based approach</u> to identify such influential observations.</font>\n', + file = htmloutfile, append = TRUE); + cat('</td></table>', + file = htmloutfile, append = TRUE); + + cat('<hr/><h2 id="regression_data"><font color=#ff0000>REGRESSION ANALYSIS</font></h2>\n', + file = htmloutfile, append = TRUE); + + # TE PE Regression + singlesample_regression(PE_TE_data,htmloutfile, append=TRUE); + + cat('<hr/><h2 id="cluster_data"><font color=#ff0000>CLUSTER ANALYSIS</font></h2>\n', + file = htmloutfile, append = TRUE); + + #TE PE Heatmap + singlesample_heatmap(PE_TE_data, htmloutfile, hm_nclust); + + #TE PE Clustering (kmeans) + singlesample_kmeans(PE_TE_data, htmloutfile, nclust=as.numeric(numCluster)) + + } +} +cat("<h3>Go To:</h3>\n", + "<ul>\n", + "<li><a href=#sample_dist>Sample distribution</a></li>\n", + "<li><a href=#corr_data>Correlation</a></li>\n", + "<li><a href=#regression_data>Regression analysis</a></li>\n", + "<li><a href=#inf_obs>Influential observations</a></li>\n", + "<li><a href=#cluster_data>Cluster analysis</a></li></ul>\n", + "<br><a href=#>TOP</a>", + file = htmloutfile, append = TRUE); +cat("</body></html>\n", file = htmloutfile, append = TRUE);
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/quantp.xml Fri Sep 14 12:22:13 2018 -0400 @@ -0,0 +1,195 @@ +<tool id="quantp" name="QuanTP" version="1.0.0"> + <description>Correlation between protein and transcript abundances</description> + <requirements> + <requirement type="package" version="1.10.4">r-data.table</requirement> + <requirement type="package" version="3.0.1">r-gplots</requirement> + <requirement type="package" version="0.7.6">r-dplyr</requirement> + <requirement type="package" version="3.0.0">r-ggplot2</requirement> + <requirement type="package" version="0.4.5">r-ggfortify</requirement> + </requirements> + <command detect_errors="exit_code"><![CDATA[ +Rscript '$__tool_directory__/quantp.r' + $experiment_design_option.sample_type + $experiment_design_option.method_type + $experiment_design_option.exp_design + '$pe_exp' + '$te_exp' + $experiment_design_option.correction_method + $cooksd_upper + $nclust + $hm_nclust + $experiment_design_option.volcano_with + '$html_file' + '$html_file.files_path' +]]></command> + <inputs> + <param name="pe_exp" type="data" format="tabular" label="Input Protein Abundance File" help="Protein abundance input file"/> + <param name="te_exp" type="data" format="tabular" label="Input RNA Abundance File" help="Transcript abundance input file"/> + <conditional name="experiment_design_option"> + <param name="sample_type" type="select" label="Select data input type" help="If the input files already have fold-change values, select Log fold-change. Else, select abundances and the tool will perform the fold-change analysis"> + <option value="multiple" selected="True">Abundances from different conditions with or without replicates (in multiple columns)</option> + <option value="logfold">Log fold-change values (or single condition abundance without replicates in single column) data</option> + </param> + <when value="logfold"> + <param name="exp_design" type="hidden" value="none" /> + <param name="method_type" type="hidden" value="none" /> + <param name="correction_method" type="hidden" value="none" /> + <param name="volcano_with" type="hidden" value="pval" /> + </when> + <when value="multiple"> + <param name="exp_design" type="data" format="tabular" help="Please check the format of the experiment design file"> + <label>Experiment design File (Please see the format below)</label> + </param> + <param name="method_type" type="select" label="Data summarization method" help="Perform T-Test on selecting Mean; Wilcoxon Ranksum Test on selecting Median"> + <option value="mean" selected="True">Mean (Default)</option> + <option value="median">Median</option> + </param> + <param name="correction_method" type="select" label="Multiple testing correction method"> + <option value="BH" selected="True">Benjamini and Hochberg (BH) (Default)</option> + <option value="holm">Holm</option> + <option value="hochberg">Hochberg</option> + <option value="hommel">Hommel</option> + <option value="bonferroni">Bonferroni</option> + <option value="BY">Benjamini and Yekutieli (BY)</option> + <option value="none">None</option> + </param> + <param name="volcano_with" type="select" display="radio" label="Volcano plot with p-value or adjusted p-value"> + <option value="pval" selected="True">P-value (Default)</option> + <option value="adj_pval">Adjusted P-value</option> + </param> + </when> + </conditional> + <param name="cooksd_upper" type="integer" value="4" optional="false" > + <label>Influential Observation cutoff: Observations > value * mean of Cook's distances (Default: "4" * mean(Cook's Distance))</label> + </param> + <param name="nclust" type="select" label="K-mean clustering: Number of clusters"> + <option value="1">1</option> + <option value="2">2</option> + <option value="3">3</option> + <option value="4" selected="True">4</option> + <option value="5">5</option> + <option value="6">6</option> + <option value="7">7</option> + <option value="8">8</option> + <option value="9">9</option> + <option value="10">10</option> + </param> + + <param name="hm_nclust" type="select" label="Hierarchical clustering: Number of clusters (from Heatmap)"> + <option value="1">1</option> + <option value="2">2</option> + <option value="3">3</option> + <option value="4">4</option> + <option value="5" selected="True">5</option> + <option value="6">6</option> + <option value="7">7</option> + <option value="8">8</option> + <option value="9">9</option> + <option value="10">10</option> + </param> + </inputs> + <outputs> + <data format="html" name="html_file" label="protein transcript correlation on ${pe_exp.name} and ${te_exp.name}"/> + </outputs> + <tests> + <test> + <conditional name="experiment_design_option"> + <param name="sample_type" value="multiple"/> + <param name="method_type" value="mean"/> + <param name="exp_design" value="exp_design_file.tabular" ftype="tabular" /> + <param name="correction_method" value="BH"/> + <param name="volcano_with" value="pval"/> + </conditional> + <param name="pe_exp" value="protein_data.tabular" ftype="tabular" /> + <param name="te_exp" value="transcript_data.tabular" ftype="tabular" /> + <param name="cooksd_upper" value="4"/> + <param name="nclust" value="4"/> + <param name="hm_nclust" value="5"/> + <output name="html_file"> + <assert_contents> + <has_text text="SAMPLE DISTRIBUTION" /> + </assert_contents> + </output> + </test> + </tests> + <help><![CDATA[ + +**What it does** + +QuanTP correlates *transcript abundance* and *protein abundance* to examine the association between them. + +It either takes in the log fold-change of abundances as input or raw abundances from different conditions where it calculates the log ratios of abundances between two conditions. + +Transcript input file can be generated from the quantitative RNA-Seq study whereas Protein input file can be generated from quantitative analysis of mass-spectrometry-based protein data. + +----- + +**Input file formats** + +**Protein data file** + +First column - Gene + +Following columns - Abundance values (or log fold-change values) + +Example of Protein input file + +====== ========= ========= ========= ========= ========= ========= ========= ========= +Gene sample1 sample2 sample3 sample4 sample5 sample6 sample7 sample8 +------ --------- --------- --------- --------- --------- --------- --------- --------- +GeneX value value value value value value value value +GeneY value value value value value value value value +GeneZ value value value value value value value value +====== ========= ========= ========= ========= ========= ========= ========= ========= + + +**Transcript data file** + +First column - Gene + +Following columns - Abundance values (or log fold-change values) + +Example of Transcript input file + +====== ========= ========= ========= ========= ========= ========= ========= ========= +Gene sample1 sample2 sample3 sample4 sample5 sample6 sample7 sample8 +------ --------- --------- --------- --------- --------- --------- --------- --------- +GeneX value value value value value value value value +GeneY value value value value value value value value +GeneZ value value value value value value value value +====== ========= ========= ========= ========= ========= ========= ========= ========= + + +**Data input type** + +If data input type is abundance, experiment design file is required. + +Example of experiment design file + +======== ========= +case groupA +control groupB +sample1 groupA +sample2 groupA +sample3 groupA +sample4 groupA +sample5 groupB +sample6 groupB +sample7 groupB +sample8 groupB +======== ========= + +Note: No title/header in experiment design file and the first two lines of the experiment design must have keyword "case" and "control" + + ]]> + </help> + <citations> + <citation type="bibtex"> +@misc{QuanTP: A software resource for quantitative proteo-transcriptomic comparative data analysis and informatics, + author={Praveen Kumar, Priyabrata Panigrahi, James Johnson, Wanda Weber, Subina Mehta, Ray Sajulga, Caleb Easterly, Brian Crooker, Mohammad Heydarian, Krishanpal Anamika, Timothy Griffin, and Pratik Jagtap}, + year={2018}, + title={QuanTP} +} + </citation> + </citations> +</tool>
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/exp_design_file.tabular Fri Sep 14 12:22:13 2018 -0400 @@ -0,0 +1,6 @@ +case G1 +control G2 +D03_01 G1 +D03_02 G1 +M14_01 G2 +M14_02 G2
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/output.html Fri Sep 14 12:22:13 2018 -0400 @@ -0,0 +1,155 @@ +<html><head></head><body> +<h1><u>QuanTP: Association between abundance ratios of transcript and protein</u></h1><hr/> + <font><h3>Input data summary</h3></font> + <ul> + <li>Abbreviations used: PE (Proteome data) and TE (Transcriptome data) </li><br> + <li>Input Proteome data dimension (Row Column): 2817 x 5 </li> + <li>Input Transcriptome data dimension (Row Column): 2817 x 5 </li></ul><hr/> +<h3 id=table_of_content>Table of Contents:</h3> + <ul> + <li><a href=#sample_dist>Sample distribution</a></li> + <li><a href=#corr_data>Correlation</a></li> + <li><a href=#regression_data>Regression analysis</a></li> + <li><a href=#inf_obs>Influential observations</a></li> + <li><a href=#cluster_data>Cluster analysis</a></li></ul><hr/> +<h2 id="sample_dist"><font color=#ff0000>SAMPLE DISTRIBUTION</font></h2> +<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> + <tr bgcolor="#7a0019"><th><font color=#ffcc33>Boxplot: Transcriptome data</font></th><th><font color=#ffcc33>Boxplot: Proteome data</font></th></tr> + <tr><td align=center> <img src="Box_TE_all_rep.png" width=500 height=500></td> +<td align=center> <img src="Box_PE_all_rep.png" width=500 height=500></td></tr></table> +<br><font color="#ff0000"><h3>Sample wise distribution (Box plot) after using mean on replicates </h3></font><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Boxplot: Transcriptome data</font></th><th><font color=#ffcc33>Boxplot: Proteome data</font></th></tr> + <tr><td align=center> <img src="Box_TE_rep.png" width=500 height=500></td> +<td align=center> <img src="Box_PE_rep.png" width=500 height=500></td></tr></table> +<br><font color="#ff0000"><h3>Distribution (Box plot) of log fold change </h3></font><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Boxplot: Transcriptome data</font></th><th><font color=#ffcc33>Boxplot: Proteome data</font></th></tr> + <tr><td align=center> <img src="Box_TE.png" width=500 height=500></td> +<td align=center> <img src="Box_PE.png" width=500 height=500></td></tr></table> +<br><br><font size=5><b><a href='PE_TE_logfold_pval.txt' target='_blank'>Download the complete fold change data here</a></b></font><br> +<br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Transcript Fold-Change</font></th><th><font color=#ffcc33>Protein Fold-Change</font></th></tr> +<tr><td align=center> <img src="TE_volcano.png" width=600 height=600></td> +<td align=center> <img src="PE_volcano.png" width=600 height=600></td></tr></table><br> +<br><br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>PCA plot: Transcriptome data</font></th><th><font color=#ffcc33>PCA plot: Proteome data</font></th></tr> + <tr><td align=center> <img src="PCA_TE_all_rep.png" width=500 height=500></td> + <td align=center> <img src="PCA_PE_all_rep.png" width=500 height=500></td></tr></table> +<hr/><h2 id="corr_data"><font color=#ff0000>CORRELATION</font></h2> +<br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Scatter plot between Proteome and Transcriptome Abundance</font></th></tr> +<tr><td align=center> <img src="TE_PE_scatter.png" width=800 height=800></td> +<tr><td align=center> +<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Method 1</font></th><th><font color=#ffcc33>Method 2</font></th><th><font color=#ffcc33>Method 3</font></th></tr> +<tr><td>Correlation method</td><td> Pearson's product-moment correlation </td><td> Spearman's rank correlation rho </td><td> Kendall's rank correlation tau </td></tr> + <tr><td>Correlation coefficient</td><td> 0.1173569 </td><td> 0.1608612 </td><td> 0.1093701 </td></tr> +</table> +<font color="red">*Note that <u>correlation</u> is <u>sensitive to outliers</u> in the data. So it is important to analyze outliers/influential observations in the data.<br> Below we use <u>Cook's distance based approach</u> to identify such influential observations.</font> +</td></table><hr/><h2 id="regression_data"><font color=#ff0000>REGRESSION ANALYSIS</font></h2> +<font><h3>Linear Regression model fit between Proteome and Transcriptome data</h3></font> + <p>Assuming a linear relationship between Proteome and Transcriptome data, we here fit a linear regression model.</p> + <table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Value</font></th></tr> +<tr><td>Formula</td><td> PE_abundance~TE_abundance </td></tr> + <tr><td colspan='2' align='center'> <b>Coefficients</b></td> </tr> + <tr><td> (Intercept) </td><td> -0.06910598 (Pvalue: 1.220723e-05 ) </td></tr> + <tr><td> TE_abundance </td><td> 0.1712395 (Pvalue: 4.168015e-10 ) </td></tr> + <tr><td colspan='2' align='center'> <b>Model parameters</b></td> </tr> + <tr><td>Residual standard error</td><td> 0.8363295 ( 2815 degree of freedom)</td></tr> + <tr><td>F-statistic</td><td> 39.31142 ( on 1 and 2815 degree of freedom)</td></tr> + <tr><td>R-squared</td><td> 0.01377265 </td></tr> + <tr><td>Adjusted R-squared</td><td> 0.0134223 </td></tr> +</table> +<font color='#ff0000'><h3>Regression and diagnostics plots</h3></font> +<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "><tr bgcolor="#7a0019"><th> <font color='#ffcc33'><h4>1) <u>Residuals vs Fitted plot</h4></font></u></th> + <th><font color=#ffcc33><h4>2) <u>Normal Q-Q plot of residuals</h4></font></u></th></tr> +<tr><td align=center><img src="PE_TE_lm_1.png" width=600 height=600></td><td align=center><img src="PE_TE_lm_2.png" width=600 height=600></td></tr> +<tr><td align=center>This plot checks for linear relationship assumptions.<br>If a horizontal line is observed without any distinct patterns, it indicates a linear relationship.</td> + <td align=center>This plot checks whether residuals are normally distributed or not.<br>It is good if the residuals points follow the straight dashed line i.e., do not deviate much from dashed line.</td></tr></table> +<br><h2 id="inf_obs"><font color=#ff0000>Outliers based on the residuals from regression analysis</font></h2> +<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> + <tr bgcolor="#7a0019"><th colspan=2><font color=#ffcc33>Residuals from Regression</font></th></tr> + <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Value</font></th></tr> +<tr><td>Mean Residual value</td><td> 1.942328e-17 </td></tr> + <tr><td>Standard deviation (Residuals)</td><td> 0.836181 </td></tr> + <tr><td>Total outliers (Residual value > 2 standard deviation from the mean)</td><td> 164 <font size=4>(<b><a href=PE_TE_outliers_residuals.txt target="_blank">Download these 164 data points with high residual values here</a></b>)</font></td> + <tr><td colspan=2 align=center><font size=4>(<b><a href=PE_TE_abundance_residuals.txt target="_blank">Download the complete residuals data here</a></b>)</font></td></td> + </table><br><br> +<br><br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "><tr bgcolor="#7a0019"><th><font color=#ffcc33><h4>3) <u>Residuals vs Leverage plot</h4></font></u></th></tr> +<tr><td align=center><img src="PE_TE_lm_5.png" width=600 height=600></td></tr> +<tr><td align=center>This plot is useful to identify any influential cases, that is outliers or extreme values.<br>They might influence the regression results upon inclusion or exclusion from the analysis.</td></tr></table><br> +<hr/><h2 id="inf_obs"><font color=#ff0000>INFLUENTIAL OBSERVATIONS</font></h2> +<p><b>Cook's distance</b> computes the influence of each data point/observation on the predicted outcome. i.e. this measures how much the observation is influencing the fitted values.<br>In general use, those observations that have a <b>Cook's distance > than 4 times the mean</b> may be classified as <b>influential.</b></p> +<img src="PE_TE_lm_cooksd.png" width=800 height=800> <br>In the above plot, observations above red line ( 4 * mean Cook's distance) are influential. Genes that are outliers could be important. These observations influences the correlation values and regression coefficients<br><br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Value</font></th></tr> +<tr><td>Mean Cook's distance</td><td> 0.0004875011 </td></tr> + <tr><td>Total influential observations (Cook's distance > 4 * mean Cook's distance)</td><td> 115 </td> + <tr><td>Observations with Cook's distance < 4 * mean Cook's distance</td><td> 2702 </td> + </table><br><br> +<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Scatterplot: Before removal</font></th><th><font color=#ffcc33>Scatterplot: After removal</font></th></tr> +<tr><td align=center><!--<font color='#ff0000'><h3>Scatter plot between Proteome and Transcriptome Abundance</h3></font> +--> <img src="TE_PE_scatter.png" width=600 height=600></td> +<td align=center> + <img src="AbundancePlot_scatter_without_outliers.png" width=600 height=600></td></tr> +<tr><td> +<table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Method 1</font></th><th><font color=#ffcc33>Method 2</font></th><th><font color=#ffcc33>Method 3</font></th></tr> +<tr><td>Correlation method</td><td> Pearson's product-moment correlation </td><td> Spearman's rank correlation rho </td><td> Kendall's rank correlation tau </td></tr> + <tr><td>Correlation coefficient</td><td> 0.1173569 </td><td> 0.1608612 </td><td> 0.1093701 </td></tr> +</table> +</td> +<td><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Parameter</font></th><th><font color=#ffcc33>Method 1</font></th><th><font color=#ffcc33>Method 2</font></th><th><font color=#ffcc33>Method 3</font></th></tr> +<tr><td>Correlation method</td><td> Pearson's product-moment correlation </td><td> Spearman's rank correlation rho </td><td> Kendall's rank correlation tau </td></tr> + <tr><td>Correlation coefficient</td><td> 0.1334038 </td><td> 0.1611936 </td><td> 0.1082761 </td></tr> +</table></td></tr></table> +<br><br><font size=5><b><a href='PE_TE_influential_observation.txt' target='_blank'>Download the complete list of influential observations</a></b></font> <font size=5><b><a href='PE_TE_non_influential_observation.txt' target='_blank'>Download the complete list (After removing influential points)</a></b></font><br> + <br><font color="brown"><h4>Top 10 Influential observations (Cook's distance > 4 * mean Cook's distance)</h4></font> +<table border=1 cellspacing=0 cellpadding=5> <tr bgcolor="#7a0019"> +<th><font color=#ffcc33>Gene</font></th><th><font color=#ffcc33>Protein Log Fold-Change</font></th><th><font color=#ffcc33>Transcript Log Fold-Change</font></th><th><font color=#ffcc33>Cook's Distance</font></th></tr> +<tr> <td> CATHL2 </td> + <td> -1.960863 </td> + <td> 4.88565 </td> + <td> 0.1432189 </td></tr> +<tr> <td> CD177 </td> + <td> -4.173263 </td> + <td> 2.057499 </td> + <td> 0.06826605 </td></tr> +<tr> <td> CATHL1 </td> + <td> -0.9912973 </td> + <td> 4.835209 </td> + <td> 0.05767091 </td></tr> +<tr> <td> HP </td> + <td> 2.570727 </td> + <td> 3.885549 </td> + <td> 0.04680496 </td></tr> +<tr> <td> AZU1 </td> + <td> -2.226356 </td> + <td> -5.561874 </td> + <td> 0.03737565 </td></tr> +<tr> <td> ELANE </td> + <td> -2.732479 </td> + <td> -2.914936 </td> + <td> 0.03266198 </td></tr> +<tr> <td> PYGM </td> + <td> -0.06079228 </td> + <td> 6.071712 </td> + <td> 0.03242859 </td></tr> +<tr> <td> LTF </td> + <td> -2.4294 </td> + <td> 2.129742 </td> + <td> 0.02725017 </td></tr> +<tr> <td> ATP1A2 </td> + <td> 0.2871971 </td> + <td> 6.446299 </td> + <td> 0.01939256 </td></tr> +<tr> <td> C13H20orf194 </td> + <td> -5.640732 </td> + <td> -0.6697401 </td> + <td> 0.01852927 </td></tr> +</table><br><br> +<hr/><h2 id="cluster_data"><font color=#ff0000>CLUSTER ANALYSIS</font></h2> +<br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>Heatmap of PE and TE abundance values (Hierarchical clustering)</font></th><th><font color=#ffcc33>Number of clusters to extract: 5 </font></th></tr> +<tr><td align=center colspan="2"><img src="PE_TE_heatmap.png" width=800 height=800></td></tr> +<tr><td colspan="2" align=center><font size=5><a href="PE_TE_hc_clusterpoints.txt" target="_blank"><b>Download the hierarchical cluster list</b></a></font></td></tr></table> +<br><br><table border=1 cellspacing=0 cellpadding=5 style="table-layout:auto; "> <tr bgcolor="#7a0019"><th><font color=#ffcc33>K-mean clustering</font></th><th><font color=#ffcc33>Number of clusters: 4 </font></th></tr> +<tr><td colspan="2" align=center><img src="PE_TE_kmeans.png" width=800 height=800></td></tr> +<tr><td colspan="2" align=center><font size=5><a href="PE_TE_kmeans_clusterpoints.txt" target="_blank"><b>Download the cluster list</b></a></font></td></tr></table><br><hr/> +<h3>Go To:</h3> + <ul> + <li><a href=#sample_dist>Sample distribution</a></li> + <li><a href=#corr_data>Correlation</a></li> + <li><a href=#regression_data>Regression analysis</a></li> + <li><a href=#inf_obs>Influential observations</a></li> + <li><a href=#cluster_data>Cluster analysis</a></li></ul> + <br><a href=#>TOP</a></body></html>
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/protein_data.tabular Fri Sep 14 12:22:13 2018 -0400 @@ -0,0 +1,2818 @@ +Gene D03_01 D03_02 M14_01 M14_02 +ELANE 90604000.0 100390000.0 623380000.0 645960000.0 +AGL 976501500.0 960830000.0 697130000.0 719100000.0 +AGK 19878000.0 16422000.0 15565000.0 20390000.0 +HSPA6 67707000.0 176540000.0 117020000.0 121110000.0 +HSPA5 11009000000.0 6568200000.0 4795000000.0 5734100000.0 +HSPA4 117790000.0 30519000.0 90678000.0 87974000.0 +HSPA9 3544300000.0 3817500000.0 2235000000.0 2270700000.0 +HSPA8 7526200000.0 7289900000.0 3520000000.0 4052400000.0 +AGA 240460000.0 291780000.0 221830000.0 173620000.0 +LGALS3 186500000.0 258100000.0 242190000.0 301190000.0 +CSNK2A2 132720000.0 155250000.0 150050000.0 161600000.0 +PMM2 1632800000.0 1802500000.0 1614800000.0 1711000000.0 +PMM1 0.0 10979000.0 8686700.0 6732400.0 +ASS1 18134000000.0 18876000000.0 12966000000.0 12270000000.0 +SPR 1922200000.0 1865500000.0 1698600000.0 1728400000.0 +RNF114 183640000.0 174460000.0 178010000.0 173870000.0 +UCHL3 274130000.0 282050000.0 254500000.0 274000000.0 +ENSBTAG00000047256 57543000.0 71609000.0 71386000.0 61095000.0 +ABCD3 55147000.0 49370000.0 55492000.0 45594000.0 +SCLY 299950000.0 329280000.0 324400000.0 272070000.0 +DHX9 213070000.0 112580000.0 88925000.0 91000000.0 +OSGEP 601030000.0 575840000.0 580200000.0 637320000.0 +NUP98 2508700.0 0.0 6975000.0 9160400.0 +PPP2R2B 29533000.0 27090000.0 35168000.0 28130000.0 +GOLIM4 55757000.0 13447000.0 28969000.0 24689000.0 +ENSBTAG00000039928 20107200000.0 17840800000.0 22329600000.0 21414400000.0 +OPA3 238630000.0 258440000.0 236320000.0 194580000.0 +OPA1 170770000.0 88756000.0 124230000.0 135980000.0 +PIK3C3 624380.0 0.0 0.0 0.0 +GK 79958000.0 91689000.0 55521000.0 67336000.0 +PTRH2 630860000.0 635300000.0 792900000.0 721580000.0 +HNRNPDL 184260000.0 197110000.0 180510000.0 178040000.0 +ENSBTAG00000024233 6670900000.0 7453900000.0 5794600000.0 6289800000.0 +TRAPPC3 350960000.0 386150000.0 288830000.0 254040000.0 +TRAPPC5 110960000.0 91402000.0 94205000.0 99412000.0 +ACLY 121870000.0 11334000.0 52304000.0 57826000.0 +CTBP2 134900000.0 121550000.0 139080000.0 127730000.0 +ITGA9 2480600.0 0.0 0.0 0.0 +ENSBTAG00000021558 0.0 0.0 0.0 0.0 +HACL1 3750000000.0 4002800000.0 4908400000.0 5092300000.0 +ITGA1 1398200.0 0.0 0.0 0.0 +NOP2 4928000.0 0.0 0.0 0.0 +ITGA6 97078000.0 42673000.0 116280000.0 130990000.0 +PDCD10 142700000.0 124020000.0 194810000.0 170930000.0 +ENSBTAG00000014423 100010000.0 99218000.0 191870000.0 184010000.0 +EDC4 10047000.0 6662500.0 0.0 13081000.0 +APOA4 5577600000.0 5684300000.0 2510700000.0 2632000000.0 +APOA5 257940000.0 333300000.0 197140000.0 201230000.0 +UFSP2 8208200.0 6119600.0 0.0 7495400.0 +XPO1 6101300.0 0.0 21163000.0 15852000.0 +CSDE1 6845000.0 10436000.0 29616000.0 35114000.0 +XPO7 1621500.0 0.0 13304000.0 5299000.0 +MRPL28 82108000.0 97797000.0 62910000.0 50735000.0 +TIPRL 223950000.0 199410000.0 192400000.0 118190000.0 +LSS 346220000.0 249770000.0 234680000.0 220640000.0 +PSMG2 66523000.0 96697000.0 25795000.0 29839000.0 +GHDC 24907000.0 27587000.0 38327000.0 43611000.0 +COL4A2 116880000.0 133790000.0 113920000.0 117830000.0 +COL4A1 145000000.0 165870000.0 135390000.0 135500000.0 +MOGAT1 23667000.0 33273000.0 24912000.0 38349000.0 +RBM12B 2074800.0 0.0 2384000.0 3078100.0 +GART 497380000.0 153590000.0 363030000.0 301340000.0 +GARS 14525000.0 0.0 35874000.0 22116000.0 +PSMD14 416870000.0 577850000.0 409550000.0 320620000.0 +ATAD1 429390000.0 455220000.0 383550000.0 484670000.0 +PSMD10 52335000.0 25236000.0 32444000.0 40355000.0 +PSMD13 1450700000.0 1441200000.0 1525200000.0 1463400000.0 +PSMD12 16339000.0 14892000.0 22908000.0 29622000.0 +ENSBTAG00000039321 939690.0 0.0 0.0 9768400.0 +FTCD 2776600000.0 2757000000.0 3259800000.0 3388300000.0 +GIT1 1902600.0 0.0 1368700.0 0.0 +SERBP1 70643000.0 58520000.0 63639000.0 60842000.0 +PPP4C 40084000.0 147770000.0 127090000.0 154860000.0 +OCRL 2204200.0 0.0 2652100.0 0.0 +GANAB 1342100000.0 362290000.0 592930000.0 651410000.0 +NUP133 506790.0 0.0 3742200.0 4045600.0 +LRPAP1 91487000.0 84230000.0 35103000.0 65126000.0 +VAPB 997680000.0 1018000000.0 1556300000.0 1647900000.0 +VAPA 1386600000.0 1518300000.0 1349600000.0 1252800000.0 +SHROOM1 5030600.0 0.0 0.0 7964200.0 +NDUFAF6 42874000.0 55512000.0 57678000.0 38059000.0 +MTIF3 105690000.0 122720000.0 103820000.0 87694000.0 +MIOS 2457000.0 0.0 0.0 0.0 +SNTB2 20388000.0 14076000.0 18128000.0 16156000.0 +IGF2R 27998000.0 5516500.0 2374800.0 0.0 +CTH 409230000.0 431710000.0 319960000.0 371070000.0 +ARL6IP1 21143000.0 75315000.0 28387000.0 107280000.0 +SPART 2390600.0 0.0 0.0 0.0 +ABHD14B 14750000000.0 13104000000.0 19532000000.0 19336000000.0 +NECAP2 15456000.0 16744000.0 49493000.0 30865000.0 +ARF4 121490000.0 160450000.0 88446000.0 64683000.0 +FAHD1 819630000.0 809200000.0 778190000.0 756100000.0 +ENSBTAG00000009622 0.0 0.0 0.0 0.0 +AP3D1 1363000.0 0.0 0.0 0.0 +EIF4B 19344000.0 10687000.0 24139000.0 10856000.0 +ZSWIM2 33653000.0 58920000.0 34138000.0 52336000.0 +ENOPH1 306200000.0 350650000.0 429480000.0 443590000.0 +SULT1A1 40564000000.0 41927000000.0 45069000000.0 47894000000.0 +TCEA1 37826000.0 40868000.0 24264000.0 21920000.0 +COX4I1 158000000.0 167970000.0 170600000.0 185850000.0 +PRKAR1A 31080000.0 32496000.0 43949000.0 55932000.0 +MOB2 48613000.0 49291000.0 43029000.0 46282000.0 +SAR1A 271310000.0 293370000.0 211060000.0 290000000.0 +SAR1B 1734000000.0 1716700000.0 1811800000.0 1703200000.0 +NIPSNAP2 330440000.0 405490000.0 367500000.0 377650000.0 +NIPSNAP1 19276000000.0 18856000000.0 18877000000.0 18937000000.0 +PIPOX 625330000.0 653730000.0 645380000.0 575450000.0 +GAA 63738000.0 62018000.0 44322000.0 49582000.0 +FGL1 493960000.0 569280000.0 681940000.0 617400000.0 +METTL27 27892000.0 39372000.0 28430000.0 46040000.0 +METTL26 1687400000.0 1635700000.0 1902400000.0 1944000000.0 +SPP2 119260000.0 137280000.0 172700000.0 152690000.0 +DDAH1 2547900000.0 2490000000.0 2409000000.0 2902700000.0 +SPHK2 24051000.0 19238000.0 12814000.0 17246000.0 +IFIH1 1711500.0 0.0 4157300.0 3620000.0 +DPT 151390000.0 167460000.0 260330000.0 286890000.0 +IPO11 1149900.0 0.0 0.0 0.0 +EEF1A1 8212600000.0 8517700000.0 7258600000.0 7119400000.0 +HMGB1 1081100000.0 1489500000.0 1323400000.0 1028700000.0 +NADSYN1 113770000.0 6961900.0 109690000.0 110230000.0 +FYCO1 25519000.0 32137000.0 0.0 0.0 +RAB2A 772460000.0 719200000.0 756150000.0 790920000.0 +RAB2B 25114000.0 16463000.0 0.0 0.0 +SRBD1 1105900.0 0.0 0.0 0.0 +ABAT 1164400000.0 1258700000.0 1034100000.0 1102200000.0 +ARHGEF2 5098900.0 8141700.0 8172000.0 11913000.0 +NFX1 5866900.0 0.0 6979000.0 8153300.0 +WDR45B 21886000.0 27828000.0 23068000.0 25707000.0 +DPYD 667600000.0 61144000.0 619680000.0 572518000.0 +AASS 169070000.0 52588000.0 81150000.0 76897000.0 +RDH5 15451000000.0 14009000000.0 16861000000.0 16638000000.0 +PEX14 23261000.0 27303000.0 29377000.0 95545000.0 +DPYS 7830700000.0 8062815000.0 9949728000.0 9439800000.0 +CLIP1 2594500.0 0.0 2500000.0 0.0 +ERAP2 2604600.0 0.0 7113200.0 5801100.0 +TIMM50 588350000.0 686280000.0 763690000.0 843270000.0 +ENSBTAG00000047529 941830000.0 1089800000.0 1011300000.0 1196300000.0 +DHRS7B 626430000.0 670140000.0 913450000.0 926770000.0 +CD46 31723000.0 38202000.0 19874000.0 31461000.0 +DMTN 3362400.0 0.0 10056000.0 0.0 +HIKESHI 279860000.0 249990000.0 92320000.0 92610000.0 +FPGT 0.0 0.0 0.0 10602000.0 +RAB21 722400000.0 730850000.0 617560000.0 708770000.0 +CFH 13710300.0 14328000.0 0.0 0.0 +PNP 17400000000.0 16460000000.0 13607000000.0 14151000000.0 +CALR 1951500000.0 2309300000.0 2060400000.0 1938700000.0 +CYB5A 43743000000.0 40782000000.0 43377000000.0 44614000000.0 +CYB5B 767030000.0 881930000.0 1064100000.0 1331500000.0 +NGP 0.0 20004000.0 90822000.0 76152000.0 +PIK3CB 720850.0 0.0 0.0 0.0 +HNRNPUL2 105420000.0 0.0 72945000.0 81483000.0 +ACTR1A 45179000.0 31150000.0 20313000.0 14220000.0 +PNN 80190000.0 15072000.0 18783000.0 9707700.0 +CHID1 237290000.0 249810000.0 215450000.0 208540000.0 +EWSR1 5933000.0 0.0 0.0 4365900.0 +PCK2 12761000000.0 13602000000.0 11250000000.0 11005000000.0 +RPN1 728920000.0 757820000.0 718510000.0 740780000.0 +TRIM13 10152000.0 0.0 0.0 0.0 +PCK1 4050800000.0 3979100000.0 2518500000.0 2623000000.0 +NTAN1 258360000.0 222820000.0 312640000.0 263420000.0 +NQO2 6187900000.0 6361700000.0 6594700000.0 7359800000.0 +NQO1 904130000.0 1059600000.0 746650000.0 832030000.0 +PRPF8 5955400.0 0.0 0.0 0.0 +CYP4F2 101860000.0 81436000.0 86279000.0 119150000.0 +PRPF6 11063000.0 0.0 15397000.0 13579000.0 +SAO 104140000.0 36364000.0 83749000.0 68739000.0 +CD177 2571100.0 0.0 22693000.0 23694000.0 +ESRP2 31452000.0 25819000.0 24752000.0 37392000.0 +CNPY4 78288000.0 107650000.0 113610000.0 105110000.0 +CNPY3 167770000.0 194140000.0 207030000.0 200080000.0 +CNPY2 732560000.0 947190000.0 440440000.0 500820000.0 +UFD1 126730000.0 145240000.0 95194000.0 111810000.0 +HDGF 68326000.0 73505000.0 81632000.0 92286000.0 +PIP4K2A 10673000.0 10341000.0 9843900.0 12262000.0 +PIP4K2B 67126000.0 87265000.0 102820000.0 106500000.0 +ARG1 58005000000.0 53362000000.0 43686000000.0 39897000000.0 +MRPL39 87432000.0 74092000.0 71958000.0 67845000.0 +PPP2R5A 17275000.0 18111000.0 24305000.0 22724000.0 +TBL2 282570000.0 292460000.0 313330000.0 315720000.0 +THOC6 32239000.0 32733000.0 52646000.0 41078000.0 +THOC5 16276000.0 22840000.0 1433900.0 11719000.0 +FAM45A 74621000.0 71954000.0 70919000.0 179150000.0 +CSAD 186550000.0 164720000.0 226960000.0 269820000.0 +MGC127055 720940000.0 743040000.0 1062500000.0 1197800000.0 +HSD3B7 484000000.0 383950000.0 694740000.0 655210000.0 +UQCRFS1 2101200000.0 1259200000.0 1537600000.0 2022200000.0 +ABCE1 56426000.0 64061000.0 70844000.0 85626000.0 +UQCRC2 3275600000.0 3474600000.0 3228500000.0 3262500000.0 +XPNPEP1 132910000.0 128610000.0 103340000.0 110780000.0 +XPNPEP2 7451300.0 26296000.0 37848000.0 32488000.0 +UQCRC1 2145600000.0 2058200000.0 1880000000.0 2180500000.0 +NUP88 73984000.0 25002000.0 28142000.0 40247000.0 +COPS8 357370000.0 344330000.0 422080000.0 446890000.0 +DDX42 2739200.0 0.0 5311700.0 7086400.0 +RETSAT 262670000.0 264170000.0 399930000.0 387770000.0 +NSDHL 4573500000.0 4450900000.0 5438900000.0 5131100000.0 +COPS2 42431000.0 44761000.0 32396000.0 37426000.0 +COPS3 24286000.0 30803000.0 16373000.0 14887000.0 +PGAM1 18876000000.0 18124000000.0 21795000000.0 21035000000.0 +KHDRBS1 84419000.0 124780000.0 109860000.0 111030000.0 +NUBPL 107590000.0 94953000.0 147250000.0 117260000.0 +COPS5 156510000.0 172850000.0 189960000.0 222370000.0 +PPOX 67183000.0 52809000.0 96132000.0 86917000.0 +ENSBTAG00000034189 10268000000.0 8968500000.0 8618000000.0 8947000000.0 +ENSBTAG00000014988 196250000.0 171830000.0 228260000.0 291040000.0 +DDX46 19016000.0 10204000.0 12633000.0 13227000.0 +TKT 5540000000.0 5862400000.0 6042700000.0 5681300000.0 +TNS3 74044000.0 80977000.0 59513000.0 76181000.0 +TNS2 6043500.0 0.0 4824700.0 3555700.0 +SDF2L1 1032600000.0 1028900000.0 1094100000.0 1060300000.0 +FDFT1 281340000.0 279520000.0 90249000.0 98227000.0 +NLN 4985700.0 10045000.0 0.0 16247000.0 +NUDT8 155510000.0 169630000.0 175090000.0 161590000.0 +NUDT9 80772000.0 80986000.0 63533000.0 65679000.0 +TARS2 363880000.0 134640000.0 340030000.0 387030000.0 +DPYSL2 350000000.0 333720000.0 380520000.0 417180000.0 +HEXA 75049000.0 76646000.0 87869000.0 82747000.0 +DLD 800970000.0 857610000.0 865910000.0 916960000.0 +NUDT1 17234000.0 18426000.0 9825600.0 5332000.0 +NAXE 3306200000.0 3282600000.0 3872300000.0 4076900000.0 +NAXD 3051500000.0 3548400000.0 3703600000.0 3862000000.0 +NUDT5 584540000.0 741120000.0 808630000.0 728750000.0 +TK2 264070000.0 209520000.0 160100000.0 178690000.0 +IGFBP7 34315000.0 32681000.0 33873000.0 0.0 +EPS8L2 88511000.0 106760000.0 114870000.0 117520000.0 +LARS 46610000.0 9544000.0 24125000.0 19301000.0 +PROZ 7825600.0 14587000.0 2317800.0 2662100.0 +CYP8B1 667620000.0 666200000.0 795720000.0 855180000.0 +ATP5F1A 16991000000.0 16930000000.0 18130000000.0 17641000000.0 +ATP5F1B 25287000000.0 25673000000.0 24487000000.0 23471000000.0 +ATP5F1C 19468000000.0 16958000000.0 12184000000.0 11747000000.0 +CYP27A1 903790000.0 972780000.0 1208500000.0 1279300000.0 +BTD 9746600.0 8417500.0 10754000.0 10810000.0 +NUBP1 67987000.0 69186000.0 44779000.0 52540000.0 +SERPINA3-8 9561600.0 10454000.0 12435000.0 0.0 +DDRGK1 60868000.0 57669000.0 79324000.0 79485000.0 +GAS2 560420000.0 676450000.0 844630000.0 792560000.0 +PROC 31292000.0 29591000.0 53981000.0 73928000.0 +SSB 116850000.0 133570000.0 75391000.0 79500000.0 +EPHX1 18118000000.0 18535000000.0 18357000000.0 19284000000.0 +EPHX2 1752800000.0 1636800000.0 1997600000.0 1629300000.0 +AMPD2 33179000.0 0.0 54503000.0 70837000.0 +EIF2B4 34473000.0 29232000.0 20830000.0 78078000.0 +RPLP0 7631800000.0 7704600000.0 8061800000.0 8108800000.0 +EIF2B2 51383000.0 50709000.0 50670000.0 71148000.0 +EIF2B3 9873800.0 13407000.0 8899700.0 11460000.0 +UGT2A1 84579000.0 91930000.0 126060000.0 118080000.0 +EIF2B1 26539000.0 48843000.0 43243000.0 11837000.0 +PRKAR2A 551720000.0 590850000.0 585270000.0 612160000.0 +ENSBTAG00000030882 3667500000.0 3503400000.0 5493200000.0 5167500000.0 +PPA1 1526300000.0 1384000000.0 1400900000.0 1589300000.0 +QPRT 18252000000.0 15281000000.0 15265000000.0 16875000000.0 +MLF2 21617000.0 28837000.0 18581000.0 10090000.0 +ALCAM 202000000.0 2386500.0 56504000.0 72712000.0 +TPM4 425550000.0 440900000.0 478600000.0 559060000.0 +TPM3 6923500000.0 7730700000.0 8677400000.0 9023700000.0 +SNRPA1 88454000.0 86279000.0 72916000.0 113600000.0 +TRADD 163720000.0 158940000.0 181470000.0 187240000.0 +ETF1 21534000.0 18769000.0 17531000.0 19991000.0 +THYN1 743050000.0 758460000.0 590320000.0 689610000.0 +PRELP 16251000.0 17287000.0 29806000.0 22530000.0 +TAGLN 0.0 50117000.0 58610000.0 53232000.0 +ETFA 24348000000.0 25834000000.0 27056000000.0 27339000000.0 +PHACTR4 129860000.0 0.0 0.0 0.0 +CLIC4 3707900000.0 3647500000.0 3338500000.0 3064500000.0 +ETFB 33544000000.0 32129000000.0 27580000000.0 27678000000.0 +CLIC2 106450000.0 97886000.0 111930000.0 119620000.0 +CLIC1 1046200000.0 1090700000.0 1212300000.0 1473900000.0 +UGDH 10738000000.0 10468000000.0 11640000000.0 12174000000.0 +SEPHS2 32550000.0 42945000.0 39271000.0 53638000.0 +SEPHS1 10374000.0 8330600.0 4543400.0 5459800.0 +TPMT 670060000.0 619080000.0 485020000.0 577750000.0 +ASGR1 6113200000.0 5552300000.0 5884200000.0 6138800000.0 +ASGR2 331910000.0 394990000.0 236440000.0 215390000.0 +TMEM141 290730000.0 280140000.0 99230000.0 293620000.0 +DDX19A 31474000.0 39435000.0 40215000.0 54203000.0 +RPS4X 30491000.0 0.0 17782000.0 26412000.0 +ENSBTAG00000001219 20467950.0 0.0 73569800.0 79261900.0 +CASP3 359540000.0 415170000.0 387070000.0 358570000.0 +TJP2 38646000.0 11493000.0 15067000.0 9138400.0 +API5 109050000.0 113860000.0 34695000.0 47719000.0 +TJP1 5194900.0 0.0 18878000.0 9246000.0 +DLST 1060600000.0 1044700000.0 870820000.0 1065800000.0 +TCP1 736420000.0 669670000.0 776370000.0 793090000.0 +PPAT 20966000.0 29632000.0 13120000.0 18347000.0 +XAB2 1850500.0 740650.0 574350.0 619370.0 +KTN1 11530000.0 3380900.0 10220000.0 8887800.0 +ST6GAL1 49151000.0 41363000.0 39712000.0 39546000.0 +PRDX6 12893000000.0 12447000000.0 16189000000.0 15559000000.0 +PRDX5 87290000.0 84731000.0 63323000.0 57958000.0 +PRDX4 5654500000.0 6074600000.0 5717700000.0 6075400000.0 +PRDX3 16752000000.0 14909000000.0 18823000000.0 19283000000.0 +PRDX2 2919000000.0 3131000000.0 5360600000.0 5386800000.0 +PRDX1 1019300000.0 1025000000.0 1153700000.0 1309400000.0 +CLGN 285640000.0 36541000.0 189800000.0 57868000.0 +SMARCA2 0.0 0.0 0.0 0.0 +OTUB1 880850000.0 783440000.0 670730000.0 734620000.0 +RABL3 92779000.0 148300000.0 109850000.0 125170000.0 +PLPBP 1428800000.0 1633400000.0 1426900000.0 1238800000.0 +PDK1 10165000.0 7346100.0 0.0 8214400.0 +CD93 2157500.0 0.0 0.0 0.0 +CAMP 0.0 0.0 25802000.0 29210000.0 +POR 1831400000.0 2041900000.0 1397900000.0 1325800000.0 +ENSBTAG00000009760 7606100.0 9257700.0 18696000.0 18436000.0 +MPRIP 6427900.0 0.0 5016100.0 12238000.0 +TOR1A 305790000.0 317760000.0 307090000.0 368290000.0 +HNRNPA3 555720000.0 512000000.0 426800000.0 480530000.0 +KANK2 0.0 0.0 0.0 0.0 +SULT2A1 5171900000.0 5448700000.0 4024200000.0 4033200000.0 +RAB1B 1410200000.0 1280800000.0 1415700000.0 1410200000.0 +RAC2 443340000.0 376110000.0 295650000.0 281910000.0 +RAC1 4427500000.0 3665000000.0 2489400000.0 2750600000.0 +SBDS 880900000.0 756580000.0 784570000.0 691050000.0 +KANK1 7241100.0 3641500.0 8258200.0 0.0 +VCL 636050000.0 178120000.0 377750000.0 339450000.0 +OSTC 1780200.0 0.0 0.0 0.0 +VCP 2473900000.0 582630000.0 1617500000.0 1552000000.0 +OLA1 187830000.0 162030000.0 141560000.0 140470000.0 +AP2A1 358620000.0 382400000.0 270240000.0 294710000.0 +AP2A2 90317000.0 107570000.0 108100000.0 89056000.0 +LYPLAL1 120220000.0 134640000.0 97200000.0 122210000.0 +CYP7B1 83710000.0 79842000.0 170780000.0 171650000.0 +MYH7B 0.0 0.0 0.0 0.0 +DPH5 26919000.0 28648000.0 31727000.0 20566000.0 +C3H1orf50 97820000.0 80161000.0 130870000.0 110850000.0 +BCKDHA 440980000.0 514390000.0 539520000.0 462700000.0 +TARS 563280000.0 196900000.0 267150000.0 286050000.0 +TIMM44 31735000.0 42468000.0 23793000.0 19507000.0 +TUFM 2112500000.0 2329200000.0 1938600000.0 2046000000.0 +LAMP1 94050000.0 113870000.0 109610000.0 106580000.0 +LYVE1 2820200.0 11048000.0 9168800.0 10459000.0 +CKB 248510000.0 222580000.0 206250000.0 181090000.0 +PTGS1 22243000.0 32032000.0 25591000.0 43116000.0 +ERGIC1 279580000.0 265720000.0 344960000.0 403800000.0 +TXNDC9 36828000.0 43137000.0 35080000.0 29061000.0 +CLEC14A 1147200.0 0.0 0.0 0.0 +PAH 2009200000.0 2021500000.0 2947200000.0 2750700000.0 +TXNDC5 514210000.0 377910000.0 475450000.0 459490000.0 +CPPED1 2123400000.0 2127900000.0 2335000000.0 2350500000.0 +DCN 30091000.0 1749300.0 22663000.0 19056000.0 +GPS1 9079400.0 10621000.0 11080000.0 12702000.0 +CALM3 54934000.0 53263000.0 59773000.0 32618000.0 +SPG21 34331000.0 34918000.0 21860000.0 76026000.0 +ACSM1 25479000000.0 23804000000.0 22502000000.0 21557000000.0 +ACSM3 1540700000.0 1479900000.0 1722800000.0 1693200000.0 +ACSM5 99503000.0 97978000.0 123510000.0 102490000.0 +MGC127133 146480000.0 162640000.0 184810000.0 197220000.0 +CYP51A1 193900000.0 204580000.0 98390000.0 103590000.0 +ATP6V0D2 39309000.0 36270000.0 44932000.0 78547000.0 +ATP6V0D1 328800000.0 394380000.0 416620000.0 345290000.0 +WDR61 96838000.0 85716000.0 161860000.0 171090000.0 +ENSBTAG00000022570 97883000.0 85722000.0 107504000.0 82386000.0 +CUL1 7831300.0 0.0 5845300.0 5734400.0 +CUL2 6551300.0 0.0 7139700.0 1875700.0 +PSMG1 44397000.0 76276000.0 96889000.0 85022000.0 +TTN 2258100000.0 2239900000.0 828920000.0 246670000.0 +ENSBTAG00000038058 932560000.0 936800000.0 1342600000.0 1106800000.0 +SLC25A3 674180000.0 799750000.0 796660000.0 685070000.0 +TRIM25 726600000.0 665630000.0 563490000.0 381700000.0 +SLC25A1 6111300000.0 5989200000.0 5546300000.0 5159800000.0 +PRMT1 38184000.0 71853000.0 66501000.0 102770000.0 +SLC25A6 1571700000.0 1525300000.0 1145400000.0 1102700000.0 +SLC25A5 197760000.0 232660000.0 190940000.0 124690000.0 +SLC25A4 12674000000.0 12867000000.0 11576000000.0 10872000000.0 +HMGCR 16572000.0 14064000.0 0.0 0.0 +LZTFL1 96947000.0 109980000.0 68434000.0 70956000.0 +DNAJA2 88548000.0 102790000.0 51893000.0 50924000.0 +DNAJA3 59809000.0 67919000.0 48789000.0 43178000.0 +DNAJA1 141230000.0 192650000.0 147090000.0 195960000.0 +RBM47 11210000.0 14633000.0 0.0 7428900.0 +PTPN12 624050.0 8377000.0 8369500.0 0.0 +KIF5B 295630000.0 0.0 171830000.0 160930000.0 +KIF5C 0.0 0.0 0.0 4770800.0 +MASP1 1542100.0 0.0 0.0 0.0 +ARCN1 1913800000.0 2012700000.0 1135800000.0 1129900000.0 +UTRN 48054000.0 8243600.0 10727000.0 17688000.0 +GLT1D1 31583000.0 24851000.0 27436000.0 29563000.0 +TTC19 80077000.0 59244000.0 72898000.0 62614000.0 +DMGDH 1457193000.0 436060000.0 1146692000.0 622967000.0 +ACADS 68931000000.0 71536000000.0 74233000000.0 73983000000.0 +MRPL21 90246000.0 81185000.0 37264000.0 33540000.0 +MRPL23 242310000.0 226920000.0 142790000.0 216000000.0 +GBA 119930000.0 145960000.0 79123000.0 107700000.0 +DNAJC25 0.0 12489000.0 9635200.0 12724000.0 +HSPG2 1531800000.0 1207100000.0 1677600000.0 1758300000.0 +GAPDH 40004000000.0 41468000000.0 47204000000.0 50988000000.0 +DTD1 81331000.0 100120000.0 90354000.0 81955000.0 +ARHGAP4 1747200.0 0.0 0.0 0.0 +SEC16A 32502000.0 0.0 3670300.0 9809500.0 +NDRG2 1718900000.0 1822200000.0 1453300000.0 1298400000.0 +ACADL 1086800000.0 1096200000.0 633480000.0 704840000.0 +ARHGAP1 269310000.0 248150000.0 301200000.0 334680000.0 +PPM1F 60990000.0 39972000.0 69854000.0 77357000.0 +SRSF7 320880000.0 319090000.0 377610000.0 317350000.0 +THEM4 1664200000.0 1662600000.0 1430500000.0 1566500000.0 +SRSF1 552240000.0 619620000.0 761760000.0 752790000.0 +PPM1B 10557000.0 10798000.0 9338700.0 9056500.0 +PPM1A 34164000.0 35360000.0 39721000.0 33018000.0 +SRSF2 96292000.0 117700000.0 128640000.0 132220000.0 +C4BPA 84900000.0 0.0 37073000.0 31331000.0 +USP47 12889000.0 0.0 5614200.0 5946600.0 +ENSBTAG00000022205 13947000.0 19471000.0 0.0 21536000.0 +DNAJB11 24536000.0 15785000.0 8182300.0 8967700.0 +ENSBTAG00000008564 5944500000.0 5631500000.0 7811500000.0 8381700000.0 +PPP6C 323990000.0 325880000.0 422310000.0 396680000.0 +ZYX 23035000.0 0.0 0.0 28305000.0 +ANXA11 144010000.0 120460000.0 164080000.0 193600000.0 +ANXA13 12053500000.0 11955400000.0 11521700000.0 10331700000.0 +CISD1 27325000.0 0.0 25938000.0 24678000.0 +UMPS 118310000.0 167690000.0 142040000.0 135130000.0 +MRPL4 64667000.0 61351000.0 46439000.0 43640000.0 +ENSBTAG00000025760 433860000.0 465000000.0 379400000.0 498370000.0 +MRPL3 70254000.0 105380000.0 73532000.0 61234000.0 +SCRN2 61118000.0 45218000.0 33133000.0 42196000.0 +PTPN6 21690000.0 22573000.0 21607000.0 28732000.0 +ATP5PO 10508000000.0 12638000000.0 7817200000.0 9343900000.0 +BTF3 231020000.0 272230000.0 133390000.0 174200000.0 +ACAD8 3418900000.0 3924400000.0 3661700000.0 3674700000.0 +ACAD9 72234000.0 55974000.0 98525000.0 118870000.0 +CYP2E1 5054000000.0 4970300000.0 8024300000.0 7904500000.0 +NPTXR 0.0 0.0 0.0 6913000.0 +BAG2 61169000.0 46480000.0 108600000.0 142740000.0 +BAG6 971060.0 0.0 2253300.0 1673500.0 +EPS15L1 14621000.0 30756000.0 21095000.0 31221000.0 +MYO1F 2003700.0 0.0 2608300.0 2392000.0 +MYO1E 0.0 0.0 0.0 0.0 +MYO1C 401100000.0 194420000.0 399030000.0 536770000.0 +MYO1B 116010000.0 4716900.0 79684000.0 91522000.0 +MSRB3 53132000.0 62502000.0 99474000.0 120170000.0 +RPS7 3306100000.0 3869000000.0 1828400000.0 2104200000.0 +RPS5 7660400000.0 6350700000.0 4476300000.0 4348200000.0 +RPS3 6454500000.0 6883100000.0 4367300000.0 4214300000.0 +RPS2 7380300000.0 8033500000.0 5052700000.0 4778500000.0 +ARRB1 31677000.0 33798000.0 44635000.0 45930000.0 +VDAC3 2416300000.0 2620700000.0 2825800000.0 3170700000.0 +VDAC2 7401700000.0 6412100000.0 8102000000.0 9155100000.0 +VDAC1 14275000000.0 13944000000.0 19133000000.0 16347000000.0 +CHMP6 314150000.0 237550000.0 133100000.0 223490000.0 +RPS9 3602400000.0 4145000000.0 3152000000.0 3421600000.0 +RPS8 5944600000.0 5776400000.0 5232100000.0 5474400000.0 +ADI1 4991580000.0 4959200000.0 5282930000.0 5221920000.0 +ATXN1L 120110000.0 311190000.0 199660000.0 198490000.0 +GMFB 254840000.0 231620000.0 306990000.0 194550000.0 +GPNMB 76137000.0 68110000.0 48446000.0 22278000.0 +HPF1 6007900.0 3765300.0 9903600.0 8534800.0 +PSMA2 2967200000.0 2848900000.0 3539400000.0 3108000000.0 +PSMA3 5654800000.0 5321000000.0 5369500000.0 4505600000.0 +PSMA1 5812500000.0 5722600000.0 5271300000.0 5751300000.0 +PSMA6 6376500000.0 6197700000.0 5663900000.0 5489800000.0 +PSMA7 4858000000.0 5176800000.0 5317400000.0 5149600000.0 +PSMA4 1462600000.0 1548400000.0 1299000000.0 1233900000.0 +PSMA5 4005100000.0 3761300000.0 3167700000.0 3074600000.0 +DSG2 14205000.0 14316000.0 21521000.0 23482000.0 +C2 4137100.0 0.0 7958000.0 9038700.0 +C6 35197000.0 3930900.0 28456000.0 25008000.0 +ENSBTAG00000038540 6037600000.0 6991200000.0 6994300000.0 6924400000.0 +GALT 131760000.0 98313000.0 126220000.0 125370000.0 +HMGCS1 811210000.0 739910000.0 250640000.0 247690000.0 +HMGCS2 26672000000.0 26273000000.0 26642000000.0 28815000000.0 +PDHA1 159230000.0 204510000.0 138880000.0 198250000.0 +COL4A3BP 1236600.0 0.0 5634100.0 6234400.0 +SEC23A 432950000.0 159330000.0 176530000.0 175370000.0 +MGLL 7309600000.0 9316000000.0 3586200000.0 3959700000.0 +SRI 221440000.0 249120000.0 204920000.0 191750000.0 +SORD 31456000000.0 29969000000.0 30798000000.0 33068000000.0 +GALE 1929300000.0 1911900000.0 1859800000.0 1826400000.0 +LGALS9 497660000.0 577400000.0 865480000.0 941970000.0 +LGALS8 791589000.0 857146000.0 1210657000.0 1443145000.0 +CS 454330000.0 482270000.0 366100000.0 361890000.0 +GALM 2995100000.0 3053400000.0 3795200000.0 3753300000.0 +FSCN1 162920000.0 134280000.0 154940000.0 141710000.0 +CYP4F22 21293000.0 18918000.0 0.0 0.0 +TDH 3134900000.0 3274100000.0 2449800000.0 2033700000.0 +MYL12B 194720000.0 194050000.0 220490000.0 199510000.0 +RPSA 1883000000.0 1811000000.0 1693500000.0 1601100000.0 +TSTA3 333430000.0 234470000.0 234540000.0 196010000.0 +EIF2AK2 377520000.0 454090000.0 337400000.0 367590000.0 +TAPBP 55613000.0 60652000.0 59451000.0 59418000.0 +HNRNPU 602190000.0 380310000.0 389530000.0 426790000.0 +COL1A2 85146000.0 2580200.0 9872600.0 12740000.0 +COL1A1 80455000.0 0.0 15069000.0 14257000.0 +TRNT1 29033000.0 32015000.0 39030000.0 26684000.0 +CSNK2B 40548000.0 39972000.0 25343000.0 38327000.0 +IDO2 477960000.0 480120000.0 579860000.0 631290000.0 +TMPO 146650000.0 89874000.0 118910000.0 48078000.0 +C3H1orf123 169640000.0 188710000.0 224450000.0 163440000.0 +PSMD11 239720000.0 243480000.0 234780000.0 219520000.0 +FCGR3A 0.0 16975000.0 19903000.0 20139000.0 +ECM1 25680000.0 0.0 8603400.0 8855500.0 +ITGAV 44244000.0 51635000.0 52070000.0 42804000.0 +FMR1 433990.0 3291000.0 3177000.0 3237800.0 +ALDH1A1 30178000000.0 31184000000.0 41013000000.0 42838000000.0 +GCDH 1128600000.0 1089700000.0 1356800000.0 1469800000.0 +ALDH1A3 18077000.0 14701000.0 15963000.0 13868000.0 +AP3B1 37226000.0 37750000.0 22788000.0 15628000.0 +PCYOX1 391690000.0 424440000.0 552560000.0 528080000.0 +RPL24 1891900000.0 2154400000.0 1423100000.0 1277900000.0 +PPP6R3 8449300.0 0.0 7997300.0 7090500.0 +RPL26 489060000.0 707860000.0 126040000.0 0.0 +RPL21 1612900000.0 1758200000.0 620210000.0 557770000.0 +ATG3 8221400.0 7295900.0 0.0 0.0 +ATG7 4286900.0 0.0 0.0 0.0 +COG1 2839900.0 0.0 12423000.0 12215000.0 +APMAP 228320000.0 217220000.0 204720000.0 201980000.0 +AADAT 167050000.0 174026100.0 114700000.0 122140000.0 +USE1 53074000.0 90766000.0 81227000.0 46430000.0 +PIGR 611920.0 0.0 899890.0 0.0 +AADAC 922300000.0 826340000.0 906140000.0 761490000.0 +HPD 10018000000.0 10950000000.0 7455200000.0 7158900000.0 +PPP1CB 254640000.0 235540000.0 216490000.0 208460000.0 +PPP1CC 53250000.0 39216000.0 80397000.0 51641000.0 +RHPN2 29363780.0 48759000.0 108390000.0 98062000.0 +SRRM1 29011000.0 26813000.0 40368000.0 39168000.0 +ATXN2 11835000.0 15182000.0 0.0 0.0 +RDH14 233570000.0 234340000.0 282620000.0 312340000.0 +PDK2 29389000.0 17428000.0 0.0 7751000.0 +RDH10 87753000.0 86810000.0 117240000.0 121830000.0 +RDH11 1385200000.0 1273200000.0 1271500000.0 1381100000.0 +RDH13 112950000.0 95914000.0 134380000.0 127930000.0 +COL6A1 560920000.0 277920000.0 399810000.0 435970000.0 +WBP2 25610000.0 67853000.0 63837000.0 77502000.0 +COL6A3 237820000.0 47933000.0 151580000.0 283110000.0 +COL6A2 190400000.0 54767000.0 243030000.0 190320000.0 +ALPL 4463900.0 0.0 0.0 3395600.0 +PECR 20885000000.0 20396000000.0 19793000000.0 19412000000.0 +ENSBTAG00000005501 192970000.0 248760000.0 246990000.0 242910000.0 +PUF60 20906000.0 17975000.0 0.0 18605000.0 +FBP1 65045000000.0 66747000000.0 51680000000.0 52391000000.0 +PFKP 6073600.0 0.0 2665000.0 3286100.0 +PLIN2 583580000.0 237620000.0 47183000.0 133320000.0 +PLIN3 2621400000.0 2364200000.0 1343500000.0 1313500000.0 +ENOSF1 470090000.0 558310000.0 700980000.0 600480000.0 +ABHD6 49025000.0 49732000.0 44783000.0 35342000.0 +CIAPIN1 175310000.0 237340000.0 108930000.0 115050000.0 +CLEC16A 15582000.0 0.0 11157000.0 12479000.0 +HSP90AB1 1288000000.0 375310000.0 616010000.0 483650000.0 +ABHD4 67417000.0 86449000.0 35660000.0 49656000.0 +PTP4A2 345460000.0 410860000.0 287700000.0 260480000.0 +DNAJC12 94857000.0 77765000.0 169670000.0 199250000.0 +UBR4 161100000.0 122210000.0 141580000.0 135280000.0 +EIF3CL 71990000.0 18834000.0 33011000.0 35526000.0 +TWF1 58576000.0 50139000.0 30358000.0 37931000.0 +DNAJC10 19480000.0 13999000.0 16427000.0 19315000.0 +MRPS9 102060000.0 115400000.0 71450000.0 64029000.0 +MRPS7 37575000.0 38519000.0 30494000.0 19420000.0 +DNAJC11 34957000.0 42931000.0 40547000.0 38152000.0 +RBP4 15649000000.0 16417000000.0 16983000000.0 19977000000.0 +PPIB 35111000000.0 35247000000.0 21494000000.0 22088000000.0 +ABHD1 102820000.0 100310000.0 23319000.0 24334000.0 +NUCB1 61629000.0 56886000.0 34321000.0 54244000.0 +EPRS 297260000.0 233970000.0 153870000.0 173470000.0 +HSDL2 2700200000.0 3325500000.0 2145400000.0 2349900000.0 +KRAS 1022200000.0 859850000.0 1002800000.0 1027600000.0 +MLYCD 331840000.0 347300000.0 306240000.0 305100000.0 +PKN1 4017400.0 0.0 3929600.0 5226400.0 +PPP2CA 134260000.0 130140000.0 232500000.0 147620000.0 +ARPC1B 808730000.0 770950000.0 983770000.0 1083900000.0 +EIF4G1 5608200.0 0.0 0.0 0.0 +ACSL1 7626700000.0 7685100000.0 2863200000.0 3067900000.0 +NDUFAF7 5012500.0 6976900.0 3652000.0 5200400.0 +ACSL5 5566400000.0 5816200000.0 5540400000.0 6121100000.0 +TERF2 0.0 941980000.0 121580000.0 391660000.0 +GRB2 381910000.0 409490000.0 491130000.0 529430000.0 +EEF1G 1995500000.0 1966100000.0 1907700000.0 2018700000.0 +ARPC1A 327440000.0 270300000.0 358730000.0 399340000.0 +PPP2CB 1057400000.0 1089200000.0 1125600000.0 1277800000.0 +RPL8 6211500000.0 6340000000.0 3803200000.0 3121200000.0 +RPL9 2897700000.0 2015600000.0 2735300000.0 2667800000.0 +RPL6 2202400000.0 2290300000.0 4190000000.0 4310100000.0 +RPL7 8624500000.0 9798800000.0 7157600000.0 6692500000.0 +HP 13151000000.0 12322000000.0 2146200000.0 2141400000.0 +RPL5 6427900000.0 7132100000.0 3164600000.0 3566500000.0 +RPL3 331680000.0 347140000.0 143950000.0 175910000.0 +NHP2 38657000.0 41178000.0 21339000.0 24876000.0 +SSU72 43922000.0 41430000.0 24257000.0 24618000.0 +NCKAP1 780440.0 0.0 1682900.0 1761400.0 +CHD5 1631900.0 0.0 0.0 0.0 +UROC1 1221900000.0 1193300000.0 1388200000.0 1373200000.0 +CHD9 0.0 0.0 0.0 998660.0 +TMPRSS11D 0.0 74001000.0 0.0 0.0 +ABHD10 312960000.0 264430000.0 226010000.0 235120000.0 +CAP1 1540500000.0 1750500000.0 1717600000.0 1746200000.0 +PRKCA 1232200.0 0.0 8318000.0 9213500.0 +SKIV2L 40142000.0 0.0 8704600.0 8287200.0 +ENSBTAG00000005315 3878900000.0 3929100000.0 3127200000.0 2912600000.0 +RAB39A 227550000.0 191740000.0 283160000.0 241600000.0 +FN3K 25930000.0 20510000.0 35652000.0 28899000.0 +MRPL11 266650000.0 288740000.0 153330000.0 185230000.0 +MRPL12 4542800000.0 4861300000.0 3849900000.0 3673300000.0 +MRPL13 47938000.0 39841000.0 29916000.0 33935000.0 +RAB3GAP2 8457000.0 29067000.0 7494600.0 6378100.0 +MRPL15 85552000.0 94379000.0 36758000.0 29568000.0 +RCN1 156720000.0 176070000.0 133240000.0 239390000.0 +RAB3GAP1 1707300.0 0.0 3354200.0 0.0 +ARPC3 568290000.0 510360000.0 300790000.0 312800000.0 +ARPC2 1148800000.0 1556800000.0 1492100000.0 1351700000.0 +UAP1 82998000.0 105080000.0 101830000.0 49927000.0 +DNAJC30 36364000.0 0.0 0.0 0.0 +ARPC5 548050000.0 536170000.0 603620000.0 633550000.0 +ARPC4 306910000.0 276120000.0 214230000.0 167730000.0 +POLR2E 141060000.0 171400000.0 84956000.0 80430000.0 +DCUN1D1 103270000.0 67983000.0 91611000.0 144330000.0 +DAG1 5326200.0 0.0 9049100.0 714880.0 +POLR2C 42211000.0 46081000.0 25492000.0 29762000.0 +POLR2B 3372400000.0 0.0 3505700000.0 1117500000.0 +RHOC 55809000.0 70109000.0 91305000.0 70828000.0 +RHOB 405230000.0 402050000.0 394730000.0 400620000.0 +AKR7A2 6478300000.0 8101500000.0 8029600000.0 7370800000.0 +ITPR1 17468000.0 12715000.0 15062000.0 0.0 +RHOG 1205300000.0 1106500000.0 944010000.0 1231100000.0 +ETHE1 21489000000.0 21463000000.0 19459000000.0 19774000000.0 +MPG 54340000.0 68660000.0 46314000.0 41844000.0 +KDSR 104270000.0 117490000.0 204820000.0 163670000.0 +TLK1 96156000.0 0.0 106110000.0 123330000.0 +MPO 12982000.0 10359000.0 25316000.0 27526000.0 +MTTP 984650000.0 343240000.0 600750000.0 524100000.0 +AIFM2 132490000.0 159500000.0 137250000.0 131560000.0 +EBF3 0.0 0.0 0.0 0.0 +AIFM1 4461000000.0 4171600000.0 4368900000.0 4180600000.0 +AGO1 18787000.0 16087000.0 10880000.0 0.0 +A1CF 286450000.0 298870000.0 280740000.0 314740000.0 +AGO2 2318400.0 0.0 3820000.0 3249500.0 +GRPEL1 525850000.0 497990000.0 671100000.0 608310000.0 +GAMT 14111000000.0 14971000000.0 13284000000.0 14177000000.0 +VBP1 96717000.0 104130000.0 128710000.0 93392000.0 +FAM120B 1652300.0 0.0 0.0 0.0 +FAM120C 6874300.0 0.0 0.0 0.0 +LAP3 4313500000.0 4709500000.0 4713700000.0 5174300000.0 +FAM120A 186910000.0 248640000.0 120780000.0 174160000.0 +MAPK14 168320000.0 169410000.0 248300000.0 203560000.0 +CD302 48548000.0 70347000.0 52364000.0 0.0 +GADL1 23780000.0 22292000.0 0.0 101470000.0 +HPGD 90565000.0 84042000.0 92608000.0 88222000.0 +AKR1B10 7053000000.0 7605400000.0 6613500000.0 7569800000.0 +OGFOD3 125060000.0 162980000.0 166610000.0 176450000.0 +IQUB 74398000.0 69742000.0 66001000.0 42149000.0 +PM20D1 20845000.0 32134000.0 15806000.0 0.0 +CACNB1 129970000.0 118150000.0 0.0 86058000.0 +REPS1 2136200.0 0.0 991870.0 1165600.0 +ACMSD 605200000.0 629570000.0 603560000.0 501760000.0 +NECTIN2 37054000.0 33012000.0 32052000.0 42192000.0 +NEURL1 12631000.0 14777000.0 0.0 0.0 +BCNT2 16510000.0 20111000.0 9740600.0 9387100.0 +UGT2B10 133900000.0 160980000.0 147790000.0 158370000.0 +GPN1 6127900.0 6759500.0 6189100.0 3103600.0 +TRIM32 2453500.0 0.0 3858800.0 4300900.0 +S100A9 159916000.0 167840000.0 722544000.0 677140000.0 +RPL4 503110000.0 498670000.0 479900000.0 541650000.0 +DNPEP 327140000.0 362000000.0 432590000.0 446150000.0 +RAP2C 367160000.0 397900000.0 510240000.0 544520000.0 +OLFML3 6979500.0 5727800.0 7857400.0 9075400.0 +FAM49A 23125000.0 19038000.0 24864000.0 30013000.0 +FAM49B 332910000.0 373670000.0 464810000.0 520740000.0 +GGA1 2038600.0 4106200.0 0.0 0.0 +USO1 360240000.0 19256000.0 80705000.0 81182000.0 +PLCD1 15003000.0 0.0 45760000.0 35687000.0 +ADO 65541000.0 56317000.0 40298000.0 44547000.0 +ADK 5012100000.0 5207200000.0 3258900000.0 3645000000.0 +HIST1H1C 416590000.0 558070000.0 868010000.0 874670000.0 +ADH6 13153000000.0 12759000000.0 12496000000.0 12672000000.0 +ADH5 3385900000.0 3437600000.0 3446000000.0 3307300000.0 +ADH4 16648230000.0 15567350000.0 20766110000.0 19670130000.0 +TACC2 0.0 0.0 0.0 0.0 +ENSBTAG00000046172 17562566000.0 17726470000.0 20585193000.0 20388383000.0 +SQOR 1109100000.0 995630000.0 1069900000.0 1068600000.0 +PRKACA 1356500000.0 1298900000.0 1662200000.0 1702400000.0 +PSMB9 94016000.0 81369000.0 124750000.0 113780000.0 +PRKACB 60229000.0 63793000.0 73864000.0 74002000.0 +PSMB7 621070000.0 734620000.0 480310000.0 506410000.0 +PSMB6 3867800000.0 3900300000.0 4740600000.0 4743000000.0 +PSMB5 1470300000.0 1744300000.0 1850700000.0 2042800000.0 +PSMB4 1792590000.0 2091992000.0 1976451000.0 1847886000.0 +PSMB3 826850000.0 721800000.0 1006000000.0 1044700000.0 +PSMB2 1468500000.0 1705200000.0 1423500000.0 1401400000.0 +PSMB1 1593440000.0 1660400000.0 1412110000.0 1591540000.0 +HDHD3 2376200000.0 2513300000.0 2301600000.0 2589600000.0 +HDHD2 588470000.0 556730000.0 593720000.0 518690000.0 +CAB39 29769000.0 35133000.0 57624000.0 47219000.0 +HDLBP 361680000.0 386800000.0 256100000.0 189210000.0 +SERPINA3 41762000.0 30834000.0 29662000.0 38854000.0 +HSPBP1 21754000.0 20353000.0 15673000.0 16147000.0 +CORO7 8290000.0 0.0 12469000.0 6888300.0 +BCL2L13 39425000.0 39254000.0 131240000.0 97630000.0 +HADHB 5024500000.0 5163300000.0 4878000000.0 4515400000.0 +ENSBTAG00000046008 51754000.0 50646000.0 52889000.0 61060000.0 +HADHA 7810500000.0 4347400000.0 4992200000.0 4992900000.0 +SAE1 50441000.0 31539000.0 56244000.0 55157000.0 +NUP43 40144000.0 0.0 18299000.0 41895000.0 +STBD1 1412100000.0 1594000000.0 1916600000.0 1690800000.0 +IDNK 111980000.0 110290000.0 194670000.0 171260000.0 +ADRM1 60952000.0 63651000.0 43783000.0 35432000.0 +HSD11B1 15999000000.0 18812000000.0 24408000000.0 24846000000.0 +TRAF2 18016000.0 25564000.0 19719000.0 18226000.0 +RMDN2 75627000.0 71334000.0 86780000.0 102600000.0 +PGRMC2 4020600000.0 3782400000.0 4559000000.0 4159300000.0 +PGRMC1 3066800000.0 2925700000.0 4196400000.0 3989600000.0 +RMDN1 443570000.0 465580000.0 303760000.0 271800000.0 +HOOK3 9239800.0 0.0 3235200.0 5034600.0 +NUP160 2633300.0 0.0 5888200.0 4537400.0 +HOOK1 71413000.0 69324000.0 71123000.0 63497000.0 +TMPRSS6 0.0 0.0 0.0 0.0 +CRYM 196840000.0 155750000.0 233910000.0 265910000.0 +ESD 7936900000.0 7056600000.0 9379200000.0 8519000000.0 +ADHFE1 583620000.0 496090000.0 618710000.0 564830000.0 +LRRC57 207920000.0 291920000.0 214080000.0 310120000.0 +LRRC59 3126700000.0 3262700000.0 2835500000.0 2633600000.0 +ABCC10 0.0 0.0 65516000.0 361800000.0 +KANK3 8741400.0 3194000.0 5812100.0 0.0 +COL14A1 15576000.0 0.0 4771100.0 4805800.0 +RPL30 0.0 0.0 19699000.0 22331000.0 +GNA14 48256000.0 66958000.0 157900000.0 178910000.0 +GNA11 407040000.0 420150000.0 455630000.0 590420000.0 +SDHA 4802000000.0 4858500000.0 4538400000.0 4066700000.0 +ENSBTAG00000030683 41010000.0 46953000.0 69939000.0 52268000.0 +SDHB 11770000000.0 11061000000.0 10321000000.0 9857500000.0 +PPCS 737630000.0 802950000.0 1117000000.0 1106600000.0 +SMARCC2 3550500.0 0.0 13419000.0 15091000.0 +MOV10 56302000.0 3591100.0 20630000.0 22509000.0 +AP1M1 35774000.0 24730000.0 40947000.0 41312000.0 +PSPC1 16356000.0 17913000.0 8598400.0 16224000.0 +MOCS3 14652000.0 15071000.0 10805000.0 14613000.0 +MOCS2 32885000.0 30252000.0 23969000.0 24408000.0 +MOCS1 546569000.0 486513000.0 449597000.0 482304000.0 +DBN1 1536100.0 0.0 0.0 0.0 +EEF2K 2474600.0 0.0 0.0 2571700.0 +ENSBTAG00000017938 42553000000.0 41638000000.0 56945000000.0 51798000000.0 +OGDH 572860000.0 362400000.0 328810000.0 259620000.0 +BLOC1S3 0.0 0.0 0.0 28403000.0 +ENSBTAG00000039356 295910000.0 3225200000.0 415370000.0 468280000.0 +COMMD2 52625000.0 65378000.0 61707000.0 52705000.0 +COMMD1 34718000.0 40083000.0 32176000.0 35737000.0 +MIB1 4806300.0 0.0 3067800.0 3299700.0 +COMMD5 198370000.0 250070000.0 185920000.0 142720000.0 +FAM114A1 23108000.0 22437000.0 9772100.0 9173300.0 +GRWD1 9316900.0 8386000.0 8337600.0 11229000.0 +FAM114A2 25211000.0 10251000.0 14594000.0 12670000.0 +METTL13 3743500.0 0.0 0.0 4329500.0 +NADK2 1701000000.0 1772300000.0 1242900000.0 1300600000.0 +C8H9orf64 346060000.0 327780000.0 344780000.0 390110000.0 +TMED2 276960000.0 218240000.0 173820000.0 269370000.0 +CAMK2D 101300000.0 103830000.0 126520000.0 136190000.0 +PTGR1 26467000000.0 27938000000.0 31029000000.0 31360000000.0 +PTGR2 1585200000.0 1528200000.0 1701900000.0 1635600000.0 +DNAH17 35157000.0 284380000.0 33579000.0 507680000.0 +MTUS2 0.0 0.0 0.0 85589000.0 +MACROD1 2471500000.0 2515700000.0 2814700000.0 2886000000.0 +COQ8A 94987000.0 105360000.0 125550000.0 98009000.0 +ENSBTAG00000032350 6921800000.0 7030200000.0 6886100000.0 7392500000.0 +CYP3A4 28068000.0 24441000.0 52335000.0 45746000.0 +CYP3A5 7547479220.0 7316867000.0 7748681000.0 8006019000.0 +UBE4B 447870.0 0.0 0.0 0.0 +UBE4A 34729000.0 0.0 24102000.0 31291000.0 +AKAP2 27555000.0 31901000.0 32028000.0 33317000.0 +TUBB4B 6402400000.0 6294500000.0 5310800000.0 5229800000.0 +TUBB4A 1015900000.0 1067800000.0 725820000.0 698060000.0 +AKAP9 14737000.0 0.0 0.0 0.0 +EIF2A 61565000.0 52591000.0 39419000.0 45453000.0 +MTREX 1563800.0 0.0 16619000.0 3245000.0 +ENSBTAG00000048013 822620000.0 884950000.0 892850000.0 824140000.0 +STARD4 87426000.0 59953000.0 32965000.0 40643000.0 +STARD5 116670000.0 104470000.0 99799000.0 115070000.0 +CAPZB 3465600000.0 3391900000.0 3682800000.0 3786000000.0 +ENSBTAG00000047632 1707400.0 0.0 0.0 0.0 +C5H12orf10 9397100.0 0.0 0.0 8583000.0 +NTN4 17052000.0 20906000.0 23420000.0 25406000.0 +HSP90B1 12420000000.0 2478500000.0 4233600000.0 4323400000.0 +TANGO2 44111000.0 0.0 0.0 0.0 +PTGDS 15234000.0 13459000.0 22534000.0 26790000.0 +STIP1 185440000.0 153580000.0 125550000.0 152890000.0 +HIP1R 82220000.0 11445000.0 20322000.0 18058000.0 +PIKFYVE 0.0 0.0 0.0 0.0 +PEPD 35231000.0 35771000.0 34546000.0 41942000.0 +AHSA1 21990000.0 21023000.0 28595000.0 17030000.0 +H3F3A 1168800000.0 1257500000.0 711530000.0 656330000.0 +MRI1 881900000.0 899840000.0 1091600000.0 1179000000.0 +GTF2I 16687000.0 3546900.0 15558000.0 189740000.0 +ATP1A2 67133000.0 0.0 15581000.0 39434000.0 +NMRAL1 5569240000.0 6200920000.0 7314650000.0 7748610000.0 +UCK1 0.0 50735000.0 31593000.0 0.0 +PRPF39 0.0 0.0 0.0 1886100.0 +DSP 194160000.0 129820000.0 148260000.0 226090000.0 +SAMM50 0.0 26456000.0 20102000.0 20843000.0 +RNF40 48980000.0 43994000.0 105910000.0 100480000.0 +GSTO1 62996000.0 59545000.0 49517000.0 62363000.0 +DNAJC9 23409000.0 23764000.0 14316000.0 16816000.0 +GLYATL3 2073500000.0 2214600000.0 2183300000.0 2218300000.0 +ENSBTAG00000023978 20829000.0 20188000.0 12135000.0 26991000.0 +DNAJC3 173330000.0 177280000.0 182330000.0 175750000.0 +EML2 0.0 25028000.0 0.0 15575000.0 +TTC36 246340000.0 284180000.0 666360000.0 612860000.0 +GOSR2 104990000.0 100350000.0 80462000.0 113490000.0 +GFPT2 49734000.0 0.0 70280000.0 116000000.0 +TTC38 55043000.0 60633000.0 49663000.0 52739000.0 +ECHDC3 590930000.0 474040000.0 328390000.0 339840000.0 +ECHDC2 7802500000.0 8424700000.0 8855900000.0 8904700000.0 +ACP6 11703000.0 12264000.0 7557300.0 10371000.0 +ACP1 857533000.0 779677000.0 1197444000.0 1224882000.0 +RAP1B 403940000.0 411310000.0 455550000.0 447420000.0 +RAP1A 2903300000.0 2640500000.0 3437400000.0 3697100000.0 +ENSBTAG00000016551 16328000.0 33599000.0 0.0 15775000.0 +ACO1 2465000000.0 1470700000.0 1202000000.0 1146700000.0 +CHDH 85069000.0 69677000.0 95955000.0 97113000.0 +RHOA 5239900000.0 5109700000.0 4933500000.0 5240400000.0 +NCOA2 0.0 0.0 0.0 0.0 +ACO2 2661300000.0 939700000.0 972870000.0 993890000.0 +SPCS2 5684700.0 8702100.0 29550000.0 18156000.0 +FAM91A1 2727600.0 0.0 0.0 0.0 +NT5C3A 101360000.0 85581000.0 85376000.0 105570000.0 +ACAT1 8787800000.0 8410200000.0 3810400000.0 4089000000.0 +ACAT2 24303000000.0 25055000000.0 29217000000.0 28229000000.0 +CXHXorf38 37401000.0 28561000.0 38271000.0 36145000.0 +F11R 52302000.0 107690000.0 143020000.0 105760000.0 +HMGB2 314160000.0 338410000.0 226370000.0 385350000.0 +MECR 215380000.0 233960000.0 85610000.0 88874000.0 +DDB1 156980000.0 49841000.0 105300000.0 102380000.0 +IVD 2247400000.0 2419500000.0 1558500000.0 1558200000.0 +AUH 1987800000.0 1969600000.0 2032300000.0 1901300000.0 +MCAT 0.0 10209000.0 8928000.0 8429800.0 +SLC27A4 21869000.0 22144000.0 21744000.0 19533000.0 +SLC27A6 26640000.0 32492000.0 35755000.0 42067000.0 +SLC27A2 189020000.0 197120000.0 163280000.0 180080000.0 +CAPZA2 530420000.0 702340000.0 857540000.0 792770000.0 +CAPZA1 3598100000.0 3548100000.0 4179400000.0 4777900000.0 +TBCK 734480.0 0.0 649440.0 1094800.0 +RAB33B 153520000.0 102720000.0 76654000.0 89618000.0 +AK3 7759100000.0 7288600000.0 6306400000.0 6348000000.0 +AK2 27980000000.0 28630000000.0 25068000000.0 26240000000.0 +TBCE 654780000.0 877120000.0 757840000.0 492860000.0 +TBCD 19009000.0 0.0 21910000.0 21921000.0 +TBCB 324000000.0 325710000.0 278390000.0 267510000.0 +AK4 395180000.0 414330000.0 248640000.0 258250000.0 +HSPE1 23608000.0 80792000.0 59368000.0 31225000.0 +SARS 430650000.0 443220000.0 419060000.0 481080000.0 +PRKD2 2163800.0 0.0 0.0 0.0 +ERBB2 4884000.0 0.0 0.0 0.0 +CTTN 43436000.0 47242000.0 43085000.0 48554000.0 +DHFR 1740200000.0 1477000000.0 1762900000.0 2165600000.0 +ERC1 38037000.0 0.0 21255000.0 28060000.0 +BAX 43360000.0 36864000.0 50065000.0 49676000.0 +PLCG2 7212300.0 2835900.0 4744600.0 5089900.0 +ATPAF1 114410000.0 117340000.0 107900000.0 98351000.0 +EPS8 13950000.0 9986100.0 8169700.0 10896000.0 +LARS2 12105000.0 206510000.0 52200000.0 87478000.0 +EIF2S1 1611500000.0 1743600000.0 1535300000.0 1527700000.0 +EIF2S3 193160000.0 166960000.0 154030000.0 152370000.0 +DDX17 305970000.0 328530000.0 263060000.0 308100000.0 +PMPCB 256030000.0 240290000.0 208780000.0 198080000.0 +PMPCA 216970000.0 187260000.0 213870000.0 207170000.0 +SELENOO 22288000.0 19184000.0 39833000.0 42724000.0 +IDH2 1441805000.0 1491810000.0 965194000.0 1065233000.0 +PSMC1 284570000.0 244550000.0 282010000.0 294600000.0 +ATP6V1B2 136720000.0 127610000.0 139710000.0 142370000.0 +PSMC3 182230000.0 199400000.0 188850000.0 184930000.0 +PSMC4 365710000.0 359000000.0 339610000.0 324770000.0 +PSMC5 160340000.0 159690000.0 115220000.0 145500000.0 +PSMC6 397980000.0 363550000.0 283000000.0 296940000.0 +ENSBTAG00000015330 629930000.0 567720000.0 527870000.0 569780000.0 +ENSBTAG00000015557 1865100.0 0.0 3106200.0 0.0 +ENSBTAG00000044081 749530000.0 568590000.0 694880000.0 792730000.0 +SH3GLB2 8463300.0 7493500.0 0.0 159370000.0 +STS 54453000.0 35884000.0 122800000.0 140690000.0 +SEC61B 489200.0 0.0 0.0 0.0 +LACTB2 4347400000.0 4472700000.0 3501800000.0 3695700000.0 +LSM1 13156000.0 18146000.0 15418000.0 0.0 +TFG 231060000.0 187190000.0 206190000.0 176890000.0 +FN3KRP 1229600000.0 1059100000.0 1035000000.0 1063000000.0 +NCLN 152080000.0 177940000.0 127820000.0 131990000.0 +EEA1 9109400.0 6243800.0 4219000.0 0.0 +NCL 585560000.0 850620000.0 516610000.0 488000000.0 +ENSBTAG00000039362 312730000.0 274800000.0 427180000.0 382030000.0 +LIN7C 347900000.0 370150000.0 380120000.0 432210000.0 +OMA1 18137000.0 27609000.0 16932000.0 0.0 +ENSBTAG00000047986 54980000.0 49961000.0 72129000.0 102000000.0 +KDM1A 3210100.0 0.0 0.0 1443000.0 +IDI1 1732100000.0 1754300000.0 1558100000.0 1603100000.0 +SPTB 3261100.0 0.0 0.0 0.0 +DHTKD1 371470000.0 35336000.0 150570000.0 166320000.0 +OSBPL1A 2996500.0 0.0 1741200.0 0.0 +LRRC47 55696000.0 45239000.0 47743000.0 57702000.0 +ENSBTAG00000005217 148730000.0 174280000.0 78814000.0 83895000.0 +EIF3H 8211300.0 16216000.0 15633000.0 15753000.0 +EIF3I 1447300000.0 1183800000.0 1070900000.0 1090900000.0 +EIF3J 67464000.0 67117000.0 98300000.0 82445000.0 +EIF3K 322890000.0 350900000.0 305450000.0 291250000.0 +EIF3L 33837000.0 28365000.0 60974000.0 56500000.0 +TSFM 241410000.0 263770000.0 250870000.0 217000000.0 +DHRS7 42224000000.0 40914000000.0 51544000000.0 57261000000.0 +DHRS4 46148000000.0 52276000000.0 49870000000.0 47558000000.0 +EIF3D 115940000.0 103310000.0 94832000.0 113740000.0 +DHRS3 259230000.0 220010000.0 260220000.0 245840000.0 +EIF3F 28659000.0 30321000.0 9737800.0 49975000.0 +EIF3G 44380000.0 38629000.0 49336000.0 33630000.0 +RARS 421020000.0 461190000.0 388120000.0 442580000.0 +FADD 635820000.0 584640000.0 484590000.0 569950000.0 +ARMC10 590670000.0 646110000.0 781230000.0 728820000.0 +SMUG1 46233000.0 0.0 32933000.0 16841000.0 +NAAA 202390000.0 236140000.0 250890000.0 311820000.0 +DAAM1 177360000.0 153410000.0 137490000.0 133140000.0 +PCYT2 43546000.0 75507000.0 52121000.0 62600000.0 +ENSBTAG00000040409 72780000.0 63350000.0 22978000.0 39084000.0 +FCHSD1 18867000.0 0.0 69529000.0 59822000.0 +IMPA2 668170000.0 508980000.0 629650000.0 727880000.0 +GUK1 600500000.0 622230000.0 819250000.0 810160000.0 +TPR 4377200.0 0.0 0.0 0.0 +PHGDH 3016500000.0 3308700000.0 3191200000.0 3583800000.0 +HRG 41582000.0 57145000.0 83441000.0 79804000.0 +NTPCR 55046000.0 58638000.0 24581000.0 17952000.0 +VAT1 384930000.0 340080000.0 287610000.0 368870000.0 +MTCH2 9909400000.0 9516700000.0 11007000000.0 10783000000.0 +FN1 272520000.0 307450000.0 376280000.0 419020000.0 +PTGES3 535710000.0 507650000.0 380220000.0 369770000.0 +PTGES2 768370000.0 715060000.0 474010000.0 524950000.0 +ECHS1 1.042e+11 93904000000.0 92745000000.0 95872000000.0 +TIAL1 40850000.0 40639000.0 26974000.0 36134000.0 +CAVIN2 283650000.0 337430000.0 314580000.0 277880000.0 +CAVIN1 6458400.0 12604000.0 18334000.0 20531000.0 +FUBP3 55878000.0 36324000.0 41284000.0 45286000.0 +FUBP1 53941000.0 98845000.0 75181000.0 65423000.0 +CCAR1 2987600.0 0.0 0.0 0.0 +CCAR2 168770000.0 5344800.0 86653000.0 72024000.0 +MTDH 536590000.0 498300000.0 553010000.0 457660000.0 +AP2B1 210690000.0 89798000.0 139700000.0 106940000.0 +EXOSC4 16148000.0 27943000.0 0.0 15291000.0 +EXOSC5 21642000.0 0.0 0.0 0.0 +HCCS 31635000.0 50132000.0 27857000.0 23881000.0 +GFER 131060000.0 131770000.0 219950000.0 214240000.0 +NCOR2 103210000.0 174110000.0 80200000.0 33893000.0 +CEACAM1 3017300.0 0.0 0.0 0.0 +NID2 51885000.0 0.0 16227000.0 20924000.0 +NID1 34640000.0 0.0 31044000.0 38118000.0 +ENSBTAG00000015047 2372900000.0 2309800000.0 2608400000.0 2341200000.0 +PLEK2 94573000.0 591440000.0 17434000.0 18573000.0 +PALM3 27516000.0 0.0 3049500.0 2271200.0 +FARP1 36974800.0 35813000.0 33092100.0 41041100.0 +MBNL1 21421000.0 20153000.0 19394000.0 18543000.0 +AGMAT 24908000000.0 28509000000.0 25680000000.0 22034000000.0 +F10 1728500.0 0.0 26107000.0 14858000.0 +EXOG 12691000.0 16761000.0 14969000.0 19034000.0 +MARC2 26408000000.0 26152000000.0 24338000000.0 24444000000.0 +RALY 468740000.0 517820000.0 508230000.0 535050000.0 +SRRT 54387000.0 0.0 37105000.0 34403000.0 +SARDH 1019100000.0 299440000.0 829370000.0 740770000.0 +VPS53 3957300.0 0.0 0.0 0.0 +ALKBH7 74969000.0 0.0 90221000.0 67076000.0 +RALB 632920000.0 666750000.0 536810000.0 533570000.0 +RALA 220130000.0 242390000.0 221350000.0 283720000.0 +KRT75 1814600.0 0.0 0.0 0.0 +TMEM126A 131110000.0 118470000.0 113320000.0 161960000.0 +PSMB10 377950000.0 502400000.0 659040000.0 377810000.0 +MOCOS 3352900.0 0.0 2758400.0 1651800.0 +SCYL1 3084200.0 0.0 0.0 3542400.0 +STXBP3 36608000.0 35304000.0 37045000.0 40702000.0 +STXBP2 200370000.0 203900000.0 201790000.0 195670000.0 +HAAO 17254000000.0 16903000000.0 19520000000.0 19763000000.0 +FASN 47526000.0 8601000.0 11537000.0 12080000.0 +SKP1 0.0 34787000.0 31102000.0 35879000.0 +DNAJB2 0.0 12936000.0 42789000.0 31512000.0 +DNAJB1 152920000.0 307470000.0 324330000.0 274000000.0 +H1FX 360370000.0 358920000.0 427780000.0 491390000.0 +CRYBG1 0.0 0.0 4198700.0 4369300.0 +OXSM 20866000.0 24353000.0 16970000.0 9761600.0 +CRYBG2 1329700.0 0.0 0.0 0.0 +AMDHD1 1158900000.0 1139600000.0 1079200000.0 1107900000.0 +AMDHD2 33673000.0 28868000.0 27764000.0 32253000.0 +HNRNPAB 651040000.0 793750000.0 568680000.0 491010000.0 +TTC23 6096600.0 0.0 0.0 0.0 +CARS 50824000.0 3450600.0 20045000.0 20439000.0 +HNRNPA0 162760000.0 164640000.0 135370000.0 138070000.0 +HNRNPA1 2463000000.0 2315400000.0 2085600000.0 2012100000.0 +ENO1 13938000000.0 13450000000.0 15301000000.0 15022000000.0 +PDF 395910000.0 370490000.0 339520000.0 327050000.0 +RACK1 7092700000.0 6367200000.0 8286400000.0 8317400000.0 +ENSBTAG00000017949 1008400000.0 875160000.0 366020000.0 491960000.0 +LLGL2 92597000.0 99576000.0 141280000.0 146720000.0 +LRRFIP1 29188000.0 40244000.0 49768000.0 72301000.0 +ACOX2 3829100000.0 3623500000.0 2174300000.0 2234100000.0 +ACOX3 4737600.0 6265800.0 7690800.0 7903200.0 +ACOX1 22954000.0 0.0 0.0 0.0 +CDK1 22698000.0 25113000.0 0.0 0.0 +CDK3 50570000.0 52637000.0 16385000.0 17364000.0 +SGSH 365980000.0 324970000.0 312780000.0 371550000.0 +IGLL1 37245000000.0 38150000000.0 49997000000.0 46525000000.0 +SRP68 72867000.0 68806000.0 47762000.0 58661000.0 +ANKFY1 22928000.0 2259300.0 9643300.0 13949000.0 +RAP2B 43747000.0 41451000.0 39737000.0 52425000.0 +LCN2 473030000.0 495830000.0 2190100000.0 2312300000.0 +PHB2 14570000000.0 15835000000.0 15572000000.0 13504000000.0 +PNPT1 108830000.0 10909000.0 46601000.0 42147000.0 +MSH3 624170.0 0.0 0.0 0.0 +SF3B1 30652000.0 0.0 12178000.0 6331600.0 +PRKAA2 22386000.0 29186000.0 24713000.0 26486000.0 +SF3B3 37779000.0 0.0 33052000.0 30302000.0 +SF3B2 12148000.0 0.0 3880900.0 4523900.0 +LIMS2 68681000.0 49389000.0 72408000.0 56323000.0 +LIMS1 176630000.0 167430000.0 156540000.0 185710000.0 +SORBS3 1780700.0 0.0 10256000.0 0.0 +SORBS2 8050700.0 0.0 25840000.0 27677000.0 +ELAC2 8743400.0 0.0 0.0 3576000.0 +SUN2 5359700.0 0.0 4328700.0 3597200.0 +ENSBTAG00000008248 27859000.0 19503000.0 21237000.0 22628000.0 +HSPD1 24779000000.0 26310000000.0 21343000000.0 21390000000.0 +OGN 277950000.0 268390000.0 407830000.0 450630000.0 +ARHGDIB 813150000.0 870900000.0 830500000.0 873750000.0 +MTX2 235680000.0 268430000.0 184300000.0 215350000.0 +MTX1 253650000.0 303580000.0 215260000.0 262030000.0 +ARHGDIA 6133000000.0 6163900000.0 4854200000.0 5586900000.0 +NANS 1369400000.0 1584200000.0 1064400000.0 1174000000.0 +PACSIN3 511050000.0 611490000.0 767040000.0 762130000.0 +PACSIN2 203080000.0 213090000.0 214120000.0 179250000.0 +COPA 285410000.0 196510000.0 207530000.0 232740000.0 +LIAS 68705000.0 85871000.0 89511000.0 98811000.0 +COPE 1925000000.0 1786300000.0 1469000000.0 1494500000.0 +SUPT16H 4967400.0 0.0 4353500.0 3144500.0 +PRKCB 5692800.0 0.0 0.0 0.0 +ENDOG 1192000000.0 979650000.0 1206600000.0 1323000000.0 +PRKCD 5263100.0 7262400.0 8195900.0 0.0 +CES1 19811000000.0 19203000000.0 27937000000.0 28072000000.0 +CES3 3299300000.0 2830800000.0 2799400000.0 2828600000.0 +CES2 2073500000.0 2364800000.0 1944500000.0 2248600000.0 +LMAN1 454230000.0 626990000.0 594030000.0 543510000.0 +LMAN2 3057800000.0 2646800000.0 4289300000.0 4657600000.0 +LMNA 2285600000.0 2570700000.0 2084900000.0 2261600000.0 +BDH2 2082010000.0 2178410000.0 2430930000.0 2244640000.0 +PM20D2 2923200.0 3977800.0 1970400.0 0.0 +DDX23 864940.0 0.0 0.0 0.0 +DDX21 31296000.0 21035000.0 12854000.0 9692300.0 +BOLA-DQB 73582000.0 85353000.0 114110000.0 106780000.0 +PFKFB1 0.0 4961200.0 19186000.0 47082000.0 +ASPG 4961100.0 4155000.0 4491200.0 4560700.0 +SCRIB 60499000.0 62792000.0 47001000.0 0.0 +GSTP1 4371300000.0 4057500000.0 6520900000.0 7469500000.0 +VTI1B 43362000.0 44407000.0 40074000.0 45530000.0 +ATP6V1C1 29188000.0 21534000.0 19369000.0 19734000.0 +SCIN 2994700.0 0.0 18311000.0 22510000.0 +FKBP15 7023100.0 0.0 3679400.0 0.0 +ADD3 20047000.0 28667000.0 26452000.0 48150000.0 +ACTG1 51480000000.0 50208000000.0 31538000000.0 32135000000.0 +ADD1 35651000.0 38069000.0 46936000.0 44303000.0 +FKBP11 2676300000.0 2445100000.0 1980400000.0 2091500000.0 +FAM3C 88594000.0 108460000.0 42139000.0 36101000.0 +PPP4R1 6162100.0 0.0 0.0 0.0 +PPIL1 22931000.0 35736000.0 10862000.0 0.0 +TPI1 36701000000.0 40003000000.0 37378000000.0 39558000000.0 +KCNB2 0.0 0.0 0.0 0.0 +TMED10 2685000000.0 2666900000.0 2134500000.0 2018500000.0 +OCIAD2 28912000.0 28398000.0 32504000.0 57851000.0 +PPP1R7 54315000.0 52746000.0 51403000.0 55323000.0 +OCIAD1 1036700000.0 998950000.0 999460000.0 954180000.0 +MAP3K2 0.0 0.0 0.0 0.0 +CCDC93 47566000.0 0.0 58470000.0 61652000.0 +NUP210 1219000.0 0.0 0.0 0.0 +PRTN3 28744000.0 39149000.0 117300000.0 126050000.0 +CTSH 777800000.0 866650000.0 641140000.0 571210000.0 +FMO3 3652900000.0 3466200000.0 4860800000.0 4801900000.0 +IARS 39339000.0 0.0 89708000.0 88815000.0 +HAL 231170000.0 278770000.0 125930000.0 140100000.0 +FMO4 17259000.0 28182000.0 23173000.0 26257000.0 +FMO5 199550000.0 205290000.0 468920000.0 488670000.0 +CTSA 542370000.0 680410000.0 589350000.0 522960000.0 +IDH1 4895100000.0 5051800000.0 4142000000.0 4384300000.0 +CTSC 3415900000.0 3569300000.0 3433600000.0 3413600000.0 +CTSD 6722100000.0 6930900000.0 6482600000.0 7143000000.0 +SH3GLB1 53229000.0 39615000.0 36921000.0 35230000.0 +CTSF 156090000.0 168280000.0 175310000.0 125690000.0 +RPL14 4248200000.0 4059900000.0 2532100000.0 2681500000.0 +RPL15 1729500000.0 1419100000.0 1279500000.0 1825300000.0 +CTSZ 18597000000.0 15600000000.0 13075000000.0 12682000000.0 +RPL17 3220600000.0 3574000000.0 1477300000.0 1384600000.0 +RPL10 3494500000.0 3467800000.0 2360700000.0 2117300000.0 +RPL11 4142800000.0 4254700000.0 3891500000.0 3549500000.0 +RPL12 3879600000.0 3666700000.0 1366500000.0 1219100000.0 +RPL13 6369100000.0 6873200000.0 4947700000.0 4429700000.0 +CTSS 641050000.0 599690000.0 792220000.0 744280000.0 +RPL18 3998000000.0 3785600000.0 3712300000.0 3291700000.0 +RPL19 3935200000.0 3942300000.0 3489600000.0 3164300000.0 +CTSW 510450000.0 540710000.0 266270000.0 121860000.0 +PCYT1A 197660000.0 224690000.0 51222000.0 49702000.0 +SMPDL3A 91053000.0 83964000.0 92986000.0 106940000.0 +INPP5D 2991900.0 0.0 0.0 2627600.0 +EMILIN1 182650000.0 51722000.0 172360000.0 195170000.0 +NME2 393490000.0 605370000.0 415900000.0 404870000.0 +RAI14 8185500.0 0.0 0.0 0.0 +LXN 33168000.0 54613000.0 36866000.0 33389000.0 +ENSBTAG00000000258 337270000.0 377260000.0 496440000.0 516970000.0 +ENSBTAG00000040418 1636300000.0 1573800000.0 2015500000.0 2007900000.0 +JDP2 0.0 0.0 0.0 0.0 +EPB42 3341000.0 0.0 2289800.0 2726300.0 +EPB41 151290000.0 90069000.0 93820000.0 104110000.0 +GATD3A 24278000000.0 24001000000.0 25014000000.0 24407000000.0 +MATR3 387950000.0 301490000.0 191690000.0 319400000.0 +PRPF3 0.0 7330700.0 0.0 5101100.0 +RGN 1.7487e+11 1.6771e+11 2.3475e+11 2.1956e+11 +ENSBTAG00000046076 0.0 30337000.0 33009000.0 16256000.0 +AHNAK 62954000.0 91922000.0 97251000.0 103110000.0 +ECH1 19804000000.0 21642000000.0 15686000000.0 16246000000.0 +ALDH16A1 1068100000.0 366670000.0 438640000.0 426760000.0 +CLUH 161810000.0 62928000.0 0.0 8364500.0 +ENSBTAG00000035915 42196000.0 42411000.0 49850000.0 44367000.0 +PDCL3 6776900.0 0.0 20900000.0 0.0 +ERP29 2794700000.0 2950700000.0 2772100000.0 2875200000.0 +PSMB8 47861000.0 29808000.0 21432000.0 47341000.0 +KATNAL2 151030000.0 26771000.0 15252000.0 59065000.0 +PHKA2 4373200.0 0.0 0.0 3915600.0 +UBA6 9560000.0 0.0 5302100.0 3196000.0 +UBA7 64562000.0 5941900.0 28619000.0 25812000.0 +SFPQ 303710000.0 200690000.0 175190000.0 149360000.0 +UBA5 18137000.0 20711000.0 16059000.0 27229000.0 +UBA2 48708000.0 21750000.0 33962000.0 38280000.0 +UBA3 24477000.0 21789000.0 28129000.0 26848000.0 +UBA1 773630000.0 238450000.0 884200000.0 623960000.0 +DECR1 32666622000.0 32417000000.0 32263000000.0 32639000000.0 +UBE2K 282550000.0 256750000.0 197150000.0 219670000.0 +NAA15 28066000.0 25629000.0 31917000.0 19460000.0 +UBE2M 452720000.0 381780000.0 433450000.0 460150000.0 +GNAQ 190540000.0 217270000.0 201800000.0 207460000.0 +GNAS 79493000.0 96616000.0 66508000.0 85022000.0 +MOGS 157710000.0 0.0 84042000.0 75009000.0 +HYOU1 263610000.0 15443000.0 113430000.0 108030000.0 +PTCD3 20875000.0 0.0 28354000.0 24777000.0 +GNAZ 7877300.0 9050100.0 12153000.0 11709000.0 +GULO 342660000.0 304250000.0 689650000.0 704580000.0 +UBE2Z 56872000.0 36546000.0 38106000.0 30645000.0 +FGGY 27503000.0 42423000.0 46648000.0 55187000.0 +UBE2S 36018000.0 29085000.0 0.0 0.0 +AGFG2 75815000.0 106240000.0 106730000.0 118310000.0 +AGFG1 57023000.0 47889000.0 68141000.0 73310000.0 +FARS2 19744000.0 17685000.0 0.0 0.0 +ASNA1 773440000.0 681330000.0 843850000.0 786840000.0 +LIPT1 17492000.0 14103000.0 10373000.0 10837000.0 +SEC14L3 127310000.0 129660000.0 112920000.0 120980000.0 +SEC14L2 984900000.0 1094500000.0 560070000.0 672510000.0 +RPL18A 2324000000.0 2565700000.0 2196100000.0 1974000000.0 +ILK 182480000.0 226830000.0 196530000.0 231450000.0 +SEC14L4 199170000.0 163940000.0 110170000.0 118640000.0 +ATP5PB 12820000000.0 11176000000.0 11918000000.0 12535000000.0 +KRT7 314600000.0 217320000.0 295580000.0 286440000.0 +GLUL 293030000.0 288230000.0 354270000.0 405070000.0 +KRT8 18233000000.0 17934000000.0 20363000000.0 21236000000.0 +NLRX1 77299000.0 0.0 81727000.0 84947000.0 +VPS45 15508000.0 11005000.0 9874800.0 13410000.0 +SRPRB 1016100000.0 1065000000.0 1279300000.0 1375400000.0 +RBM8A 74197000.0 125190000.0 77868000.0 54192000.0 +SRPRA 190710000.0 226460000.0 142170000.0 129120000.0 +TALDO1 7582400000.0 6507700000.0 5879900000.0 7114500000.0 +PGLYRP1 663080000.0 787700000.0 1130900000.0 1184200000.0 +EHHADH 13963000000.0 6189600000.0 10016000000.0 9594100000.0 +CAST 20281000.0 0.0 28188000.0 25237000.0 +VCPIP1 10327000.0 0.0 0.0 4287000.0 +ARL3 234110000.0 209430000.0 316550000.0 285210000.0 +ENSBTAG00000003523 33756000.0 23727000.0 78845000.0 66920000.0 +EPB41L2 86358000.0 0.0 57522000.0 66166000.0 +EPB41L5 9423300.0 13086000.0 12743000.0 10754000.0 +THRAP3 18137000.0 8054300.0 7085900.0 9484700.0 +ACSS3 2699900000.0 2846900000.0 2387700000.0 2533100000.0 +ACSS2 27423000.0 0.0 27983000.0 15104000.0 +NDUFA8 1531000000.0 1667300000.0 1335900000.0 1981500000.0 +NDUFA9 2293400000.0 2357600000.0 2591500000.0 2678400000.0 +UAP1L1 27004000.0 21346000.0 21899000.0 20449000.0 +VPS4A 60431000.0 65159000.0 65855000.0 78673000.0 +VPS4B 40045000.0 30555000.0 50786000.0 38584000.0 +TARDBP 106330000.0 95081000.0 115350000.0 94660000.0 +RAB9A 432190000.0 484800000.0 317400000.0 324330000.0 +CYP1A1 149550000.0 129750000.0 244960000.0 216540000.0 +CYP1A2 2177100000.0 2196200000.0 2350000000.0 2187000000.0 +MTR 34685000.0 11951000.0 15125000.0 14127000.0 +LGMN 3619800000.0 3529000000.0 4623100000.0 5256100000.0 +GSTM1 25500200000.0 24900500000.0 32739000000.0 35628000000.0 +GSTM3 19779000000.0 21608000000.0 27427000000.0 29564000000.0 +AGXT 7129300000.0 7491900000.0 7986200000.0 7641600000.0 +FARSB 182730000.0 189830000.0 144080000.0 132310000.0 +PALLD 8679300.0 0.0 8171400.0 0.0 +STX12 152630000.0 170780000.0 112460000.0 153720000.0 +BLMH 76783000.0 78981000.0 103480000.0 95359000.0 +STX17 73252000.0 59136000.0 42960000.0 50284000.0 +EFHD2 808170000.0 795930000.0 1392700000.0 1440200000.0 +ECPAS 2819100.0 0.0 2187500.0 2767300.0 +SAT2 23647000.0 20440000.0 0.0 24250000.0 +COLGALT1 51908000.0 65978000.0 38164000.0 34711000.0 +CUTC 544350000.0 580280000.0 499070000.0 541680000.0 +GPRIN3 1549000.0 21820000.0 0.0 8729200.0 +EIF5 154010000.0 151970000.0 126210000.0 154450000.0 +EIF6 757590000.0 754530000.0 749640000.0 723560000.0 +PDCD6 189920000.0 203270000.0 130340000.0 91371000.0 +INSR 0.0 0.0 0.0 3701900.0 +HIST2H2BE 395700000.0 507480000.0 383010000.0 392640000.0 +GNE 149300000.0 229290000.0 126710000.0 115170000.0 +LTA4H 231960000.0 227620000.0 272880000.0 291150000.0 +SPTBN5 62616000.0 75120000.0 62204000.0 59634000.0 +SPTBN1 1066100000.0 618950000.0 538410000.0 514710000.0 +RNF170 52684000.0 43726000.0 43482000.0 0.0 +CBR4 1895000000.0 1597400000.0 1625500000.0 1595900000.0 +CBR1 45169000000.0 44583000000.0 51518000000.0 52021000000.0 +NSF 33267000.0 0.0 40164000.0 38914000.0 +TLN1 1353100000.0 1035300000.0 807240000.0 824130000.0 +DPP8 2329600.0 0.0 0.0 0.0 +DPP9 9858600.0 0.0 0.0 0.0 +GBE1 820100000.0 388300000.0 423290000.0 506750000.0 +DPP3 889540000.0 704960000.0 691810000.0 788880000.0 +SUOX 1001300000.0 1052500000.0 1037200000.0 1192300000.0 +FDPS 6532500000.0 7222300000.0 10255000000.0 9408800000.0 +DPP7 36044000.0 55035000.0 54175000.0 51587000.0 +PCNA 1196200000.0 1183200000.0 676130000.0 570480000.0 +ANXA3 6227200000.0 6986200000.0 7616800000.0 9010800000.0 +ANXA2 12392000000.0 13715000000.0 15879000000.0 16667000000.0 +ANXA5 3831200000.0 3899000000.0 5371000000.0 5123200000.0 +ANXA4 57509000000.0 61393000000.0 65991000000.0 71300000000.0 +ANXA7 501658000.0 493602000.0 493771000.0 546609000.0 +ANXA6 28930820000.0 31134100000.0 17575962000.0 18065563000.0 +ANXA9 873130000.0 778370000.0 1477100000.0 1120300000.0 +MCM7 28289000.0 0.0 16851000.0 15345000.0 +MCM6 51609000.0 0.0 5192100.0 8313100.0 +MCM5 33963000.0 87058000.0 348180000.0 307680000.0 +GCLM 451700000.0 494290000.0 478850000.0 476610000.0 +MCM3 40561000.0 0.0 30498000.0 51654000.0 +MCM2 35871000.0 0.0 15951000.0 4519800.0 +MESD 111960000.0 100020000.0 95917000.0 100560000.0 +SAMHD1 8304200.0 0.0 8626300.0 23533000.0 +AMACR 1741500000.0 1704500000.0 1293400000.0 1431100000.0 +DNPH1 54309000.0 82524000.0 36791000.0 84126000.0 +RPA1 15562000.0 16349000.0 14598000.0 13098000.0 +RPA2 51733000.0 44246000.0 43839000.0 52806000.0 +NDUFS1 561530000.0 436080000.0 364380000.0 345850000.0 +NDUFS2 154630000.0 147360000.0 149270000.0 166000000.0 +NDUFS3 2121800000.0 1951700000.0 2142600000.0 2222400000.0 +COQ9 1663063000.0 1696043000.0 1470893000.0 1294859000.0 +ENSBTAG00000024700 71916000.0 83590000.0 65987000.0 67174000.0 +NDUFS7 532520000.0 435100000.0 210290000.0 51955000.0 +COQ5 581520000.0 521600000.0 494730000.0 446930000.0 +CGNL1 112190000.0 53094000.0 90884000.0 88675000.0 +COQ7 438900000.0 485280000.0 324680000.0 310660000.0 +AHCY 28662000000.0 28293000000.0 30398000000.0 34027000000.0 +COQ3 498400000.0 528560000.0 400750000.0 454190000.0 +M6PR 106230000.0 97835000.0 120750000.0 175820000.0 +AOC1 109010000.0 24364000.0 77766000.0 73010000.0 +AOC3 812360000.0 89551000.0 583060000.0 584640000.0 +PEX11G 135580000.0 112890000.0 171920000.0 169500000.0 +PARS2 0.0 0.0 0.0 0.0 +BHLHE22 0.0 0.0 71158000.0 0.0 +AOX1 1953100000.0 716570000.0 2251900000.0 2376600000.0 +CHMP2A 66669000.0 67094000.0 60484000.0 37740000.0 +DHX15 58899000.0 6545100.0 23096000.0 25348000.0 +HIBADH 8889900000.0 8918900000.0 5910600000.0 5851400000.0 +ZFYVE1 1341600.0 0.0 0.0 0.0 +NHLRC3 46149000.0 57803000.0 48254000.0 58503000.0 +NHLRC2 4883300.0 0.0 0.0 0.0 +PPT1 470770000.0 513060000.0 475800000.0 483950000.0 +CPT2 4147000000.0 4138600000.0 3426100000.0 3578900000.0 +DSC2 241120000.0 230170000.0 229060000.0 239900000.0 +DDX31 91006000.0 65068000.0 35418000.0 59505000.0 +NDUFB11 49711000.0 74042000.0 26878000.0 23153000.0 +NDUFB10 2443300000.0 2292600000.0 2145700000.0 2451000000.0 +PYGB 5038500.0 0.0 0.0 0.0 +PITRM1 4401000.0 0.0 0.0 0.0 +GOT2 15168000000.0 15711000000.0 17377000000.0 16890000000.0 +LYN 9120000.0 9320000.0 15355000.0 16437000.0 +GOT1 3939400000.0 3894500000.0 3347300000.0 3298500000.0 +PYGL 10260000000.0 7764600000.0 8177400000.0 8027400000.0 +PYGM 0.0 641520000.0 342240000.0 326890000.0 +PFAS 116970000.0 5426000.0 46715000.0 55055000.0 +ENSBTAG00000017021 14312000.0 0.0 0.0 0.0 +SOD2 1335700000.0 1396400000.0 1474900000.0 1534700000.0 +SOD3 651200000.0 822230000.0 948790000.0 899470000.0 +VWA8 341790300.0 175610000.0 302330000.0 298046300.0 +SOD1 3476600000.0 3398000000.0 2284900000.0 2682900000.0 +ENSBTAG00000017759 124570000.0 74164000.0 222560000.0 165920000.0 +SAFB 66893000.0 50901000.0 43734000.0 42652000.0 +RANGAP1 7067200.0 7009300.0 9361700.0 7900600.0 +EMC10 57073000.0 39983000.0 69614000.0 64358000.0 +ENSBTAG00000013274 223280000.0 232510000.0 154660000.0 172040000.0 +QTRT1 0.0 0.0 0.0 0.0 +CGN1 41303000.0 30008000.0 46164000.0 56803000.0 +DOHH 27498000.0 33151000.0 35121000.0 27837000.0 +OTUD6B 89678000.0 76788000.0 51341000.0 77433000.0 +FBXL8 11310000.0 14429000.0 8266600.0 6405100.0 +H2AFV 34890000.0 45036000.0 56157000.0 51847000.0 +SNRNP200 21724000.0 13020000.0 21837000.0 15255000.0 +H2AFY 103830000.0 117450000.0 109050000.0 119900000.0 +ZADH2 8863900000.0 8843300000.0 9978500000.0 10337000000.0 +NIPSNAP3A 1325900000.0 1362400000.0 2047200000.0 1620400000.0 +DDX5 53475000.0 50959000.0 37654000.0 40410000.0 +C2H2orf72 769520000.0 825430000.0 1014000000.0 1080100000.0 +SERPING1 108060000.0 96561000.0 191090000.0 215290000.0 +DDX1 306970000.0 4202400.0 68413000.0 94384000.0 +ENSBTAG00000025929 4945200000.0 4806800000.0 4763500000.0 4842400000.0 +UPF1 77443000.0 29656000.0 19780000.0 31133000.0 +H2AFJ 579290000.0 540270000.0 643320000.0 691320000.0 +NIT2 3787900000.0 3926500000.0 5231900000.0 5395100000.0 +NIT1 1914900000.0 1826900000.0 2278000000.0 2208000000.0 +ENSBTAG00000031788 12251000.0 12424000.0 18979000.0 43093000.0 +TYSND1 5808300.0 0.0 4561700.0 0.0 +ENSBTAG00000031785 8269900000.0 10404000000.0 7464800000.0 6968900000.0 +NFKBIA 7862600.0 23052000.0 20722000.0 29700000.0 +CLTA 40441000.0 27067000.0 56439000.0 62688000.0 +PPP1R21 12882000.0 0.0 7442800.0 5347900.0 +CLTC 836140000.0 1051100000.0 516710000.0 577210000.0 +CLTB 0.0 17690000.0 36525000.0 28991000.0 +ENSBTAG00000047121 573270000.0 576240000.0 730850000.0 594070000.0 +MMS19 13350000.0 0.0 7990600.0 8650500.0 +RMDN3 103650000.0 102940000.0 69490000.0 80083000.0 +SFN 2360700000.0 2952100000.0 235350000.0 2126500000.0 +CRYZ 21334000000.0 23920000000.0 31852000000.0 34523000000.0 +HARS 252340000.0 241990000.0 248210000.0 291880000.0 +UBE3A 7016600.0 0.0 3453700.0 0.0 +IBA57 583430000.0 616490000.0 637590000.0 648760000.0 +UBXN4 213830000.0 164540000.0 191520000.0 132110000.0 +MYD88 51357000.0 56938000.0 59210000.0 62204000.0 +ENSBTAG00000039237 4651500000.0 5692400000.0 6623100000.0 6332400000.0 +MPDZ 53991000.0 40869000.0 24504000.0 26572000.0 +TOP2A 781230.0 0.0 0.0 0.0 +NACA 228680000.0 236110000.0 324470000.0 381610000.0 +FAF1 7673300.0 0.0 0.0 4751500.0 +PGM5 0.0 0.0 0.0 0.0 +FAF2 40872000.0 62389000.0 27656000.0 41586000.0 +PGM1 4440800000.0 4537800000.0 4827600000.0 4844900000.0 +PGM2 1469200000.0 1543700000.0 1479500000.0 1498000000.0 +PGM3 18637000.0 19628000.0 18628000.0 26373000.0 +MIA3 12156000.0 0.0 5733200.0 0.0 +SART3 6301200.0 0.0 14114000.0 12604000.0 +SART1 3263400.0 0.0 0.0 0.0 +VPS41 1267800.0 0.0 3822500.0 3939900.0 +SLC25A42 772200000.0 811080000.0 866880000.0 798000000.0 +BCAM 20884000.0 8829400.0 21085000.0 21786000.0 +SEC23B 33867000.0 4725400.0 1743000.0 3546800.0 +GLOD4 7264400000.0 7997780000.0 7767330000.0 7859090000.0 +GCH1 62330000.0 102280000.0 42598000.0 43051000.0 +ENSBTAG00000004632 66761000.0 61788000.0 54623000.0 57342000.0 +DBT 824520000.0 907080000.0 970660000.0 905350000.0 +ECI2 11998000000.0 10503000000.0 13667000000.0 12394000000.0 +ECI1 49053000000.0 50408000000.0 50309000000.0 52872000000.0 +HTT 0.0 0.0 0.0 0.0 +NUP155 5398100.0 0.0 6560200.0 11867000.0 +IPO7 558980.0 0.0 3549600.0 0.0 +IPO4 1282600.0 0.0 0.0 0.0 +IPO5 207010000.0 15104000.0 134650000.0 131320000.0 +ACTR3 589490000.0 577080000.0 690190000.0 496180000.0 +ACTR2 339810000.0 375250000.0 353270000.0 398350000.0 +NRBP1 13467000.0 10765000.0 8163100.0 12121000.0 +VPS11 4068100.0 0.0 0.0 7676800.0 +ENSBTAG00000047815 4144800000.0 4195600000.0 5895500000.0 6026800000.0 +SDCBP 70516000.0 44222000.0 88539000.0 34817000.0 +CARS2 24571000.0 21477000.0 27373000.0 26183000.0 +CASK 15213000.0 0.0 18538000.0 0.0 +ENSBTAG00000009029 75577000.0 89719000.0 52020000.0 56676000.0 +RAB8B 201540000.0 194470000.0 360960000.0 273410000.0 +TNPO3 5451400.0 0.0 2109700.0 2213100.0 +RAB8A 485730000.0 599500000.0 837160000.0 524010000.0 +NAA25 0.0 0.0 0.0 0.0 +ENSBTAG00000032899 630520000.0 606760000.0 938120000.0 930280000.0 +POLDIP2 468910000.0 514350000.0 448140000.0 450470000.0 +MARS2 20453000.0 14362000.0 27635000.0 20742000.0 +SCPEP1 38589000.0 38425000.0 33093000.0 28333000.0 +MAPK3 16307000.0 18497000.0 13223000.0 12973000.0 +MAPK1 32167000.0 360170000.0 365250000.0 555200000.0 +ALDH18A1 19420000.0 0.0 11583000.0 12943000.0 +DUSP3 36057000.0 40290000.0 11706000.0 13104000.0 +SHPK 472510000.0 478650000.0 678080000.0 691770000.0 +DAZAP1 185500000.0 236050000.0 160090000.0 103110000.0 +PHYHD1 156520000.0 204840000.0 302510000.0 294870000.0 +COPS6 495700000.0 443710000.0 459260000.0 530150000.0 +RDX 805490000.0 654060000.0 490460000.0 551000000.0 +FERMT2 113130000.0 67171000.0 78370000.0 81067000.0 +COPS4 32884000.0 41763000.0 31851000.0 37734000.0 +GGCT 233070000.0 204120000.0 196030000.0 192620000.0 +VKORC1 61907000.0 59484000.0 75052000.0 83794000.0 +BCAP31 592330000.0 727100000.0 1673600000.0 1411300000.0 +VPS35 286760000.0 111630000.0 210500000.0 194850000.0 +WDR91 14384000.0 20024000.0 12884000.0 19905000.0 +GLB1 18835000.0 21894000.0 17772000.0 20107000.0 +DECR2 8421500000.0 7468100000.0 9069000000.0 8870000000.0 +STAT5B 4568300.0 0.0 9181900.0 8121500.0 +DGUOK 305470000.0 246800000.0 279560000.0 208370000.0 +CSE1L 25854000.0 0.0 29781000.0 23297000.0 +XYLB 2292200000.0 2565300000.0 2974100000.0 3121500000.0 +TBC1D17 4090500.0 0.0 9381800.0 8648500.0 +FBL 647010000.0 648360000.0 573420000.0 506720000.0 +RPL35 76659000.0 37473000.0 67295000.0 70764000.0 +NUMA1 15611000.0 0.0 6404500.0 7354300.0 +PMVK 580610000.0 630530000.0 426150000.0 425490000.0 +DHX30 13084000.0 0.0 9093200.0 7888100.0 +HSPA1A 7164100000.0 7135300000.0 6877400000.0 7024000000.0 +ACAD10 1869400000.0 1890500000.0 1708000000.0 1918800000.0 +ACAD11 1778300000.0 1825100000.0 1658100000.0 1390400000.0 +CARNS1 26010000.0 0.0 29741000.0 36175000.0 +HSPA1L 17586000.0 21160000.0 5967700.0 4641700.0 +IDH3A 336200000.0 308770000.0 239140000.0 233020000.0 +IDH3B 29051000.0 44462000.0 31891000.0 20229000.0 +HCFC1 2931600.0 0.0 0.0 0.0 +HAGH 24107000000.0 26914000000.0 26049000000.0 27911000000.0 +PLOD3 80936000.0 18980000.0 83295000.0 105260000.0 +CPNE1 110960000.0 107260000.0 155020000.0 172540000.0 +PLOD1 3693000.0 0.0 10977000.0 11895000.0 +NRAS 245220000.0 230330000.0 319550000.0 266400000.0 +DNASE2 68387000.0 69568000.0 48293000.0 60554000.0 +FOXRED1 157620000.0 147230000.0 136350000.0 173040000.0 +PXN 12182000.0 15878000.0 15583000.0 16581000.0 +G3BP1 45086000.0 63729000.0 97263000.0 38720000.0 +ATP5ME 24444000.0 0.0 31522000.0 34050000.0 +UFL1 46619000.0 43829000.0 38802000.0 43535000.0 +RAD21 4059800.0 0.0 0.0 6626400.0 +USP13 207820000.0 24651000.0 119790000.0 155630000.0 +ALDH6A1 19642000000.0 19976000000.0 20662000000.0 21415000000.0 +USP15 309830000.0 336150000.0 340380000.0 376260000.0 +SNRPB 141900000.0 121870000.0 147290000.0 130060000.0 +SNRPA 185060000.0 214310000.0 229040000.0 164990000.0 +INPP1 23503000.0 25989000.0 26898000.0 24516000.0 +SMU1 28960000.0 29580000.0 26580000.0 28683000.0 +AKR1D1 14875000000.0 14827000000.0 23590000000.0 19503000000.0 +TXNDC12 74339000.0 78128000.0 57526000.0 52461000.0 +LYZ1 25736000.0 29417000.0 51292000.0 51012000.0 +ALOX15B 1223700.0 0.0 6840200.0 8275900.0 +PUDP 75299000.0 61468000.0 58442000.0 66633000.0 +SCFD1 110330000.0 93305000.0 91714000.0 89646000.0 +SCFD2 8836900.0 10435000.0 4580800.0 5348200.0 +PRKAG1 296650000.0 285340000.0 498310000.0 528240000.0 +ENSBTAG00000033457 6347400.0 0.0 0.0 0.0 +OXNAD1 94587000.0 120280000.0 164910000.0 101440000.0 +OR5C1 0.0 0.0 0.0 0.0 +P4HA1 7716400.0 9334300.0 0.0 0.0 +ANP32B 562810000.0 573060000.0 588350000.0 461320000.0 +ANP32A 624360000.0 565370000.0 806750000.0 758330000.0 +FDXR 42381000.0 61825000.0 44386000.0 42522000.0 +TYK2 3559800.0 0.0 5734900.0 4897500.0 +TAT 83209000.0 85139000.0 27537000.0 30543000.0 +SUPT5H 6593900.0 0.0 9198100.0 9927000.0 +NAPG 49828000.0 86448000.0 90989000.0 94570000.0 +NAPA 2474500000.0 2299100000.0 2695400000.0 2939900000.0 +THY1 58617000.0 71541000.0 103160000.0 112830000.0 +MRPL58 136080000.0 173210000.0 91316000.0 94382000.0 +CDC42BPA 0.0 0.0 0.0 0.0 +LARP1 9911400.0 4562500.0 5089400.0 0.0 +SF3A3 11972000.0 21823000.0 15991000.0 10811000.0 +SCCPDH 347860000.0 359370000.0 155270000.0 173930000.0 +FXR1 0.0 0.0 0.0 0.0 +FXR2 566330.0 0.0 0.0 0.0 +AGXT2 2033600000.0 2164700000.0 1992200000.0 1943400000.0 +TNS1 51592000.0 49311000.0 44125000.0 35372000.0 +CNDP2 879220000.0 773960000.0 834790000.0 926310000.0 +ISOC2 5804500000.0 5445500000.0 4634200000.0 5754100000.0 +NPL 92108000.0 106490000.0 168470000.0 151080000.0 +D2HGDH 29669000.0 21354000.0 25421000.0 28003000.0 +PTER 38595000.0 35761000.0 43510000.0 43702000.0 +MITD1 64099000.0 69749000.0 84130000.0 63031000.0 +LDAH 472750000.0 464300000.0 666910000.0 711230000.0 +GADD45GIP1 93871000.0 83479000.0 70578000.0 79378000.0 +ANGPTL2 45317000.0 110000000.0 0.0 18200000.0 +ENSBTAG00000045947 105390000.0 105790000.0 63896000.0 70149000.0 +ACE2 2099800.0 0.0 1754200.0 1588500.0 +ENSBTAG00000038755 3936800.0 0.0 482040.0 0.0 +TSN 43318000.0 37383000.0 76082000.0 59054000.0 +PBDC1 61749000.0 33676000.0 95979000.0 118530000.0 +ELAVL1 1186000000.0 1358600000.0 1059000000.0 1075100000.0 +ELAVL2 19138000.0 0.0 0.0 0.0 +EXOC4 2023800.0 13398000.0 4638700.0 0.0 +PDS5A 1400100.0 0.0 0.0 0.0 +PDS5B 3002000.0 0.0 5250600.0 4941100.0 +MYO18A 52755000.0 3316000.0 4502300.0 5529400.0 +GPLD1 53482000.0 58724000.0 37160000.0 41510000.0 +TST 83417000000.0 92519000000.0 82189000000.0 85271000000.0 +MTSS1 33478000.0 27590000.0 28621000.0 19223000.0 +HSCB 83669000.0 70868000.0 80276000.0 89499000.0 +CHCHD3 3555200000.0 3746800000.0 3415800000.0 3009900000.0 +RPL7A 7649000000.0 8908800000.0 4133100000.0 3626300000.0 +ENSBTAG00000013919 219170000.0 255700000.0 500010000.0 343930000.0 +FARSA 136430000.0 154570000.0 149110000.0 191440000.0 +FAM151B 47369000.0 78331000.0 40283000.0 30222000.0 +PAICS 331530000.0 351180000.0 233380000.0 238250000.0 +OVCA2 160330000.0 194060000.0 193740000.0 237200000.0 +KYAT3 101060000.0 93288000.0 71930000.0 64825000.0 +VTA1 80212000.0 38637000.0 64384000.0 74800000.0 +NUDT2 34307000.0 34963000.0 26506000.0 27378000.0 +KIF1BP 1692100.0 0.0 0.0 1991800.0 +DLG1 27402000.0 0.0 18952000.0 16966000.0 +NUDT3 98520000.0 103960000.0 165520000.0 104970000.0 +ENSBTAG00000047973 24365000.0 33321000.0 27937000.0 26154000.0 +ALDH8A1 4643100000.0 4324400000.0 4919600000.0 4288600000.0 +PPP1R18 46250000.0 12306000.0 5631200.0 0.0 +BNIP1 30599000.0 26737000.0 52232000.0 57399000.0 +XIRP2 0.0 0.0 0.0 0.0 +MBL2 122620000.0 247640000.0 200410000.0 160600000.0 +GZMA 16291000.0 16177000.0 15085000.0 12719000.0 +MTHFD1L 26655000.0 0.0 7904800.0 12836000.0 +EMC9 33199000.0 34794000.0 24974000.0 26067000.0 +EMC8 51464000.0 60986000.0 0.0 0.0 +FBXO30 446960.0 0.0 3441900.0 3452300.0 +FLOT1 61710000.0 71473000.0 75339000.0 99006000.0 +FLOT2 50093000.0 47270000.0 37697000.0 42926000.0 +EMC2 211670000.0 252160000.0 236680000.0 196880000.0 +EMC1 18069000.0 12972000.0 78505000.0 79944000.0 +CNRIP1 124140000.0 147730000.0 151410000.0 136310000.0 +EMC7 216120000.0 236940000.0 209180000.0 182810000.0 +MYH10 162230000.0 90808000.0 187030000.0 152330000.0 +MYH11 229420000.0 7773100.0 41284000.0 50474000.0 +MYH14 668250000.0 473960000.0 302160000.0 292090000.0 +GNS 223800000.0 245030000.0 237340000.0 183390000.0 +AP3M2 76186000.0 73059000.0 90849000.0 83538000.0 +SMG8 352830000.0 620930000.0 629200000.0 519790000.0 +HTRA2 367850000.0 347110000.0 415940000.0 387400000.0 +RTRAF 238520000.0 245700000.0 271460000.0 296140000.0 +PIK3AP1 29274000.0 20729000.0 35952000.0 35059000.0 +HINT3 215780000.0 246900000.0 243860000.0 232490000.0 +HMBS 30448000.0 36603000.0 19161000.0 11053000.0 +SMC3 25150000.0 0.0 9207400.0 6436900.0 +SMC2 8596200.0 0.0 3625900.0 3440300.0 +CDC37 70338000.0 120510000.0 112560000.0 106510000.0 +ALAS1 25913000.0 10762000.0 21266000.0 27961000.0 +ENSBTAG00000009788 386416000.0 352430000.0 341101000.0 309659600.0 +NMT1 15797000.0 16725000.0 13496000.0 14111000.0 +KIAA0513 0.0 0.0 0.0 0.0 +CPOX 11336000000.0 11394000000.0 8707500000.0 9394100000.0 +GRIPAP1 24820000.0 0.0 72981000.0 47968000.0 +TNKS1BP1 39419000.0 0.0 29646000.0 28123000.0 +LTF 42915000.0 0.0 114580000.0 116590000.0 +HIBCH 4241700000.0 4132700000.0 4709600000.0 5251600000.0 +LASP1 1335544000.0 1273349200.0 1449800000.0 1446300000.0 +AFDN 41584000.0 16285000.0 34720000.0 28935000.0 +PGLS 1833100000.0 1747500000.0 1958100000.0 1597800000.0 +C8B 30897000.0 30673000.0 32070000.0 39114000.0 +PPP5C 40807000.0 54437000.0 46279000.0 46954000.0 +LMOD1 2222000.0 0.0 1729100.0 0.0 +GLS2 141190000.0 160970000.0 106750000.0 130330000.0 +MAP7 20235000.0 33258000.0 40724000.0 48240000.0 +RBM4 38117000.0 53283000.0 33343000.0 29917000.0 +GALK2 78803000.0 70339000.0 79531000.0 94072000.0 +RPL23A 237880000.0 240200000.0 87890000.0 68838000.0 +SPCS3 448690000.0 429640000.0 389390000.0 385990000.0 +ARL8B 223200000.0 240640000.0 72128000.0 86819000.0 +EGFR 24920000.0 0.0 5029300.0 7906400.0 +CAT 1.6038e+11 1.6105e+11 2.0388e+11 2.1283e+11 +ACADM 13801000000.0 13652000000.0 7419900000.0 8075200000.0 +WDR82 234795000.0 243163000.0 277772000.0 228740000.0 +ENSBTAG00000011511 85385000.0 117110000.0 118970000.0 90806000.0 +CAD 3402500.0 0.0 2550100.0 2382100.0 +NUBP2 180660000.0 148320000.0 194510000.0 187300000.0 +PGD 495050000.0 457100000.0 523150000.0 554190000.0 +DYSF 4419600.0 0.0 18537000.0 9096200.0 +VPS25 85790000.0 101610000.0 75405000.0 72503000.0 +DYNC1I1 0.0 0.0 0.0 0.0 +C29H11orf54 4003600000.0 4877300000.0 4697800000.0 4497900000.0 +VPS28 135570000.0 105570000.0 111350000.0 95796000.0 +VPS29 325920000.0 249880000.0 191740000.0 191370000.0 +NUDC 86640000.0 74091000.0 76593000.0 67288000.0 +ESYT1 18123000.0 0.0 32907000.0 41289000.0 +TOP1 10436000.0 0.0 2039800.0 2531900.0 +PGP 586810000.0 690450000.0 596490000.0 524140000.0 +ENSBTAG00000047700 1403100000.0 1066900000.0 1424100000.0 1326700000.0 +PTPN23 5620900.0 0.0 4329200.0 3843600.0 +COA7 129100000.0 205990000.0 133650000.0 110920000.0 +TMEM214 4794400.0 6609600.0 2969300.0 4280700.0 +LGALS3BP 107060000.0 109560000.0 116480000.0 114840000.0 +SEPSECS 61554000.0 55800000.0 56364000.0 74506000.0 +PLEKHO2 0.0 25159000.0 0.0 0.0 +PDE12 17861000.0 14436000.0 24687000.0 24332000.0 +EXOC2 2331100.0 0.0 0.0 1853600.0 +ARSB 2706300.0 3346600.0 4055100.0 2919000.0 +CA3 38243000000.0 37004000000.0 46031000000.0 50774000000.0 +CA2 3205000000.0 2902700000.0 5933500000.0 5051400000.0 +EXOC8 3578300.0 0.0 3851000.0 0.0 +HEXB 103290000.0 109690000.0 142870000.0 142930000.0 +RBMX 302330000.0 355300000.0 238690000.0 266880000.0 +ACBD3 9610500.0 0.0 6283000.0 6515500.0 +ANK3 162600000.0 7528600.0 62632000.0 63091000.0 +ACBD5 148270000.0 148500000.0 140500000.0 130460000.0 +ACBD4 3843900.0 2497500.0 3147900.0 2644600.0 +MON2 5290600.0 0.0 0.0 0.0 +BZW1 57658000.0 56809000.0 34106000.0 35548000.0 +EEF2 2931200000.0 1920200000.0 1498400000.0 1299300000.0 +BZW2 13909000.0 13759000.0 6033700.0 6981800.0 +PDGFRB 0.0 0.0 3116000.0 3568600.0 +GSTA4 709120000.0 697980000.0 622170000.0 830090000.0 +GSTA5 12943000000.0 13936000000.0 16929000000.0 23978000000.0 +EVA1B 51585000.0 50796000.0 81191000.0 81173000.0 +UFC1 544900000.0 611290000.0 577060000.0 645150000.0 +GSTA2 38311000000.0 43348000000.0 57110000000.0 53731000000.0 +GSTA3 2.1924e+11 2.4298e+11 3.1553e+11 3.1526e+11 +CTSB 2541800000.0 2366000000.0 1616300000.0 1702500000.0 +CBR3 10356000000.0 9958100000.0 9579600000.0 9426600000.0 +ENSBTAG00000012096 2217400000.0 1885900000.0 1857600000.0 1927000000.0 +PYCR3 1546300000.0 1789700000.0 1898500000.0 1805100000.0 +PYCR2 149850000.0 182610000.0 78988000.0 148580000.0 +FAM234A 2756200.0 0.0 5206400.0 0.0 +RSU1 450940000.0 572230000.0 609850000.0 573940000.0 +DDX39B 298980000.0 292000000.0 293450000.0 283450000.0 +DDX39A 5907700.0 0.0 4796700.0 5202600.0 +ADAMTS9 2626300.0 0.0 0.0 0.0 +STRAP 193600000.0 236300000.0 168070000.0 222360000.0 +CBFB 52134000.0 54014000.0 78914000.0 66049000.0 +ENSBTAG00000014567 294970000.0 239570000.0 300230000.0 352560000.0 +DMAC2 85419000.0 63575000.0 64880000.0 77769000.0 +EEFSEC 55534000.0 87310000.0 0.0 62581000.0 +CDH2 46358000.0 18627000.0 69219000.0 79557000.0 +BOLA-DRA 58384000.0 82213000.0 122320000.0 108350000.0 +ENSBTAG00000022715 2687300.0 0.0 0.0 0.0 +LIPA 50770000.0 48269000.0 37941000.0 50055000.0 +EIF2B5 24215000.0 1338500.0 9175800.0 8104200.0 +RAB5A 312690000.0 259990000.0 319220000.0 364050000.0 +RAB5C 1660000000.0 1430400000.0 1633200000.0 1677100000.0 +RAB5B 403350000.0 354430000.0 544380000.0 508580000.0 +SEC24D 128220000.0 0.0 52058000.0 51576000.0 +ENSBTAG00000019516 13134000000.0 11632000000.0 14799000000.0 16692000000.0 +PEX11B 272220000.0 267720000.0 339030000.0 274530000.0 +SEC24A 71015000.0 18151000.0 48095000.0 79276000.0 +SSH3 2483800.0 0.0 0.0 0.0 +SEC24C 181350000.0 13546000.0 72687000.0 66382000.0 +SEC24B 22112000.0 0.0 45096000.0 34487000.0 +PAFAH1B3 144860000.0 83680000.0 111300000.0 137220000.0 +PAFAH1B2 86750000.0 89999000.0 96167000.0 101770000.0 +HOGA1 7100700000.0 6155300000.0 6957500000.0 8384900000.0 +PDXDC1 26882000.0 9763900.0 19787000.0 29095000.0 +MIF4GD 77140000.0 46076000.0 72345000.0 107100000.0 +SCARB1 9266400.0 9190300.0 0.0 0.0 +AZU1 247400000.0 219380000.0 1052000000.0 1132300000.0 +PLEKHA4 1928600.0 0.0 0.0 0.0 +PLEKHA6 12805000.0 14291000.0 14130000.0 0.0 +PLEKHA7 1987200.0 0.0 9393600.0 8458600.0 +MRPL47 68460000.0 75243000.0 36930000.0 31232000.0 +MRPL46 94184000.0 102650000.0 91550000.0 82342000.0 +ALAD 33235000000.0 34914000000.0 32079000000.0 36304000000.0 +MRPL44 122210000.0 156430000.0 89494000.0 103010000.0 +ACTB 17736000.0 25743000.0 16310000.0 0.0 +DGKQ 1090600.0 0.0 7425600.0 7571500.0 +PPA2 4050400000.0 3908000000.0 5469600000.0 5055900000.0 +STARD10 1800200000.0 1526800000.0 2040500000.0 1703800000.0 +CPT1A 32894000.0 47487000.0 8313800.0 15266000.0 +ERAP1 16281500.0 0.0 10619300.0 11372800.0 +ENSBTAG00000023939 2566200000.0 2673600000.0 1773300000.0 2133900000.0 +NMRK1 52266000.0 0.0 0.0 64103000.0 +RRAS 228850000.0 226530000.0 228110000.0 214840000.0 +ARFGAP2 12324000.0 16617000.0 18504000.0 19259000.0 +ARFGAP3 685370000.0 756040000.0 542920000.0 579520000.0 +LAMB1 9697100.0 12890000.0 9470700.0 0.0 +DHX36 2696300.0 0.0 0.0 14887000.0 +COPZ1 588390000.0 482700000.0 315150000.0 401950000.0 +NEK7 81473000.0 68748000.0 115720000.0 65171000.0 +DDX58 6671000.0 5974900.0 15110000.0 17887000.0 +COPZ2 707750000.0 748880000.0 501720000.0 617060000.0 +RUVBL1 117020000.0 110350000.0 115430000.0 122700000.0 +RUVBL2 14817000.0 13085000.0 12566000.0 16152000.0 +U2AF1 45344000.0 60756000.0 25495000.0 25709000.0 +PLA2G12B 136610000.0 170650000.0 203050000.0 186320000.0 +ADAR 10871000.0 0.0 10159000.0 10194000.0 +NEK9 21046000.0 0.0 18473000.0 15532000.0 +GATM 7805700000.0 7892800000.0 8093700000.0 8469000000.0 +ADAL 32325000.0 0.0 30523000.0 24772000.0 +SF3A1 122070000.0 29598000.0 79787000.0 97968000.0 +CDC42BPB 1249300.0 0.0 0.0 0.0 +FAM129B 2901300.0 0.0 6655100.0 3952700.0 +TXNRD1 114110000.0 138550000.0 134210000.0 165230000.0 +CAPG 62536000.0 64629000.0 77192000.0 58357000.0 +ENSBTAG00000045566 0.0 0.0 0.0 0.0 +TPT1 627510000.0 567620000.0 788890000.0 642440000.0 +BUB3 222660000.0 147350000.0 130970000.0 137130000.0 +ALYREF 693790000.0 606400000.0 677590000.0 667880000.0 +PEX16 106300000.0 76329000.0 82310000.0 84735000.0 +ABCF2 3403100.0 0.0 0.0 0.0 +BLVRB 6931700000.0 6964900000.0 10194000000.0 11632000000.0 +ADSSL1 30329000.0 22639000.0 43563000.0 36805000.0 +GLTPD2 79006000.0 66847000.0 38275000.0 46452000.0 +EGLN1 309270000.0 529290000.0 283660000.0 262130000.0 +OGT 19323000.0 0.0 10103000.0 0.0 +MTHFD1 11596000000.0 4501100000.0 6251700000.0 6220600000.0 +YBX1 135600000.0 207300000.0 204320000.0 168400000.0 +IK 1543700.0 0.0 0.0 0.0 +C13H20orf194 7396300.0 0.0 97805000.0 271210000.0 +ANXA1 4579000000.0 5169100000.0 7308500000.0 7974700000.0 +NSD1 0.0 0.0 0.0 620410.0 +METAP2 10718000.0 12859000.0 8494600.0 8970200.0 +ATP6V1D 134220000.0 131310000.0 138780000.0 151610000.0 +CCDC47 23335000.0 26694000.0 24014000.0 26111000.0 +TCERG1 10251000.0 0.0 5204600.0 3527900.0 +RNPEP 31859000.0 29488000.0 43701000.0 34715000.0 +HSD17B11 17377000000.0 17068000000.0 25299000000.0 25530000000.0 +TPM1 299860000.0 256020000.0 367770000.0 613850000.0 +ADSL 263140000.0 271300000.0 262270000.0 318900000.0 +ENSBTAG00000005146 22442000.0 22511000.0 15543000.0 0.0 +AS3MT 271990000.0 280180000.0 405770000.0 399760000.0 +MYH3 0.0 0.0 6009200.0 0.0 +COASY 150380000.0 165660000.0 165410000.0 177020000.0 +MYH9 1772000000.0 1077400000.0 832330000.0 947130000.0 +USF3 9132100.0 0.0 35814000.0 38437000.0 +NAE1 5794800.0 7390000.0 8693200.0 11052000.0 +RANBP1 343700000.0 330080000.0 254660000.0 325180000.0 +RANBP3 12670000.0 16124000.0 0.0 0.0 +CADM1 28020000.0 0.0 8779900.0 7802300.0 +GNB4 99642000.0 45080000.0 82338000.0 84992000.0 +SIPA1 97852000.0 98736000.0 160710000.0 176630000.0 +GNB1 1342400000.0 1233100000.0 1389900000.0 1387400000.0 +GNB2 1679000000.0 1657900000.0 1639100000.0 1831100000.0 +NUDT12 51318000.0 56029000.0 64071000.0 95023000.0 +GCN1 39797000.0 0.0 5424300.0 6099500.0 +NUDT16 162890000.0 131250000.0 114470000.0 116820000.0 +NUDT14 594020000.0 595070000.0 739850000.0 1036700000.0 +ZW10 9845300.0 2967500.0 11651000.0 9866100.0 +NUDT19 24868000.0 28780000.0 28047000.0 24514000.0 +BREH1 283230000.0 225000000.0 174730000.0 206590000.0 +STX8 38721000.0 37912000.0 50684000.0 36790000.0 +RTCB 123380000.0 138010000.0 102720000.0 98178000.0 +SDS 46777000.0 53276000.0 73606000.0 75933000.0 +STX5 71603000.0 59136000.0 66599000.0 96818000.0 +STX4 89167000.0 134210000.0 201510000.0 173740000.0 +STX7 124930000.0 114390000.0 200370000.0 133560000.0 +GDPD1 16522000.0 16502000.0 51349000.0 36970000.0 +RPS3A 13813000000.0 14613000000.0 8544700000.0 7706500000.0 +RANBP2 39593000.0 3067100.0 13984000.0 12454000.0 +POLR1E 0.0 0.0 0.0 0.0 +PON1 4949100000.0 4240700000.0 10127000000.0 9879600000.0 +ECE1 6871100.0 0.0 0.0 0.0 +ENSBTAG00000046839 407830000.0 409380000.0 408110000.0 453520000.0 +IQGAP1 24154000.0 0.0 34302000.0 40179000.0 +IQGAP2 873920000.0 551000000.0 463040000.0 491300000.0 +YWHAZ 3234100000.0 3695200000.0 3090600000.0 2909000000.0 +DRG2 35680000.0 44124000.0 31161000.0 26767000.0 +DRG1 22748000.0 24259000.0 12560000.0 15912000.0 +XXYLT1 64440000.0 81354000.0 71679000.0 91124000.0 +NOP58 11176000.0 4710800.0 2239900.0 2060300.0 +PITHD1 359960000.0 418260000.0 431230000.0 405450000.0 +YWHAQ 1400500000.0 1215100000.0 1269800000.0 1293800000.0 +NOP56 76954000.0 27374000.0 31913000.0 30629000.0 +IL18 30462000.0 18741000.0 27154000.0 32994000.0 +YWHAH 1149800000.0 1225100000.0 769800000.0 894100000.0 +RPE 323040000.0 198320000.0 535720000.0 407210000.0 +YWHAB 5727400000.0 5511600000.0 5893600000.0 5329900000.0 +AP1B1 169130000.0 182490000.0 108680000.0 91104000.0 +YWHAG 7743700000.0 9202000000.0 6286500000.0 7009500000.0 +YWHAE 6775900000.0 6647100000.0 4726000000.0 5840300000.0 +CARD19 353580000.0 404430000.0 448720000.0 377840000.0 +MAT2A 558590000.0 595560000.0 427420000.0 443560000.0 +ATAD3A 136330000.0 133260000.0 130950000.0 138110000.0 +MAT2B 705870000.0 730610000.0 671760000.0 808180000.0 +ENSBTAG00000045888 346750000.0 354100000.0 373550000.0 321430000.0 +C1S 64847000.0 12858000.0 14731000.0 16395000.0 +C1R 69160000.0 18341000.0 28192000.0 31003000.0 +TUBA4A 785840000.0 656190000.0 797400000.0 710660000.0 +CALD1 1082700000.0 1308800000.0 1468400000.0 1762800000.0 +TBKBP1 1509200.0 0.0 0.0 0.0 +PANK4 3948900.0 0.0 0.0 0.0 +COQ6 59849000.0 50569000.0 56437000.0 62308000.0 +NUDT13 131080000.0 116190000.0 124630000.0 83189000.0 +ENSBTAG00000037775 592840000.0 528960000.0 522800000.0 448610000.0 +ABI1 187770000.0 184470000.0 180110000.0 161880000.0 +ROCK1 10470000.0 0.0 0.0 7899700.0 +ROCK2 2215400.0 0.0 0.0 0.0 +CUL4A 36752000.0 17740000.0 41355000.0 26649000.0 +CYP2C19 497210000.0 580150000.0 1892900000.0 1790100000.0 +ILF3 42156000.0 0.0 7112000.0 5134900.0 +TGFBI 88139000.0 81617000.0 98123000.0 90576000.0 +ENSBTAG00000036298 256420000.0 264220000.0 402030000.0 284840000.0 +ILF2 70511000.0 63837000.0 50811000.0 45532000.0 +IMMT 927790000.0 228460000.0 455220000.0 405310000.0 +ACADVL 8322400000.0 8860600000.0 5366600000.0 5353600000.0 +NDUFB9 1235100000.0 1096700000.0 1154000000.0 1026800000.0 +RAB4A 181780000.0 184510000.0 241500000.0 219160000.0 +PCCB 3828300000.0 3636100000.0 3739800000.0 3718300000.0 +PCCA 5796600000.0 6197300000.0 3987000000.0 4292100000.0 +FCHO2 0.0 6572500.0 14968000.0 14542000.0 +URAD 255210000.0 439250000.0 225060000.0 266510000.0 +FAM213B 386020000.0 313920000.0 298990000.0 269150000.0 +PECAM1 0.0 0.0 0.0 4601500.0 +SUGT1 428080000.0 506410000.0 723290000.0 606380000.0 +TPD52 180300000.0 237530000.0 215690000.0 201420000.0 +UHRF1 1666200.0 0.0 0.0 0.0 +ENSBTAG00000045976 98042000.0 79451000.0 59155000.0 72863000.0 +CLN5 22306000.0 20719000.0 18241000.0 21148000.0 +ZC3HAV1 189970000.0 228910000.0 239090000.0 183390000.0 +CLINT1 150520000.0 184360000.0 98048000.0 166920000.0 +ANKRD44 1765800.0 0.0 1735600.0 1690500.0 +ANKRD46 23663000.0 25008000.0 19104000.0 0.0 +CXADR 13022000.0 6060600.0 31805000.0 0.0 +CRYL1 2396600000.0 2147500000.0 3126600000.0 2966000000.0 +WNK1 2530600.0 0.0 0.0 0.0 +ACSM2B 6259700000.0 5592200000.0 5505100000.0 5814100000.0 +ACOT8 1135500000.0 1315000000.0 1544400000.0 1611800000.0 +ACOT4 103590000.0 61606000.0 36650000.0 36937000.0 +ACOT2 26532000.0 22850000.0 20575000.0 14209000.0 +SHMT2 1321400000.0 1297400000.0 1109700000.0 1058800000.0 +SHMT1 17289000000.0 18519000000.0 18169000000.0 17758000000.0 +ENSBTAG00000026758 12335000000.0 12942000000.0 11463000000.0 10971000000.0 +TOR1AIP1 24495000.0 28768000.0 33809000.0 44241000.0 +PLD2 0.0 0.0 0.0 175260000.0 +PLD3 7580800.0 7581400.0 7355200.0 8852000.0 +LIMA1 37050000.0 50951000.0 54039000.0 72864000.0 +KIF27 6570000.0 0.0 3391900.0 3677200.0 +PPFIBP2 1289100.0 2278800.0 0.0 0.0 +ETNPPL 84978000.0 77498000.0 103510000.0 105490000.0 +PNPO 1725300000.0 1952000000.0 2186800000.0 2205000000.0 +ZBTB20 3068400.0 0.0 0.0 5106800.0 +SRSF3 554290000.0 574500000.0 937140000.0 757390000.0 +STX2 45526000.0 60440000.0 83757000.0 80654000.0 +DDI2 383010000.0 459100000.0 212490000.0 201080000.0 +IRGQ 5032400.0 0.0 0.0 4849000.0 +HRAS 15169000.0 26928000.0 21251000.0 22042000.0 +CC2D1A 10218000.0 0.0 3717500.0 0.0 +SEPT8 27216000.0 19427000.0 30765000.0 33351000.0 +SEPT7 501890000.0 589180000.0 562650000.0 543480000.0 +SEPT6 34101000.0 26813000.0 40200000.0 32064000.0 +PITPNA 131310000.0 80383000.0 65588000.0 49210000.0 +SEPT2 345250000.0 525260000.0 478470000.0 420110000.0 +HSPH1 16783000.0 2844000.0 22130000.0 26716000.0 +MFF 53244000.0 54983000.0 79051000.0 60458000.0 +ENSBTAG00000006819 9962400.0 0.0 19760000.0 15460000.0 +GK5 82056000.0 76538000.0 101350000.0 110070000.0 +MFN1 497220.0 0.0 4105800.0 4202200.0 +NARS 330330000.0 298460000.0 289420000.0 350250000.0 +JUP 133570000.0 79926000.0 88505000.0 123300000.0 +YARS 373690000.0 368340000.0 343620000.0 324900000.0 +RBM39 1515200.0 0.0 7448200.0 6772100.0 +AGPS 4178900.0 21599000.0 19859000.0 18484000.0 +FAM98B 24826000.0 21573000.0 17895000.0 38848000.0 +TFR2 126280000.0 3731500.0 43219000.0 32150000.0 +PARP9 1094100.0 0.0 0.0 0.0 +ENSBTAG00000039643 16599000.0 37180000.0 0.0 0.0 +SEC13 1278700000.0 1335000000.0 1646000000.0 1634400000.0 +EPN1 1021600.0 0.0 0.0 0.0 +PARP1 29526000.0 30078000.0 39371000.0 40924000.0 +EPN3 11776000.0 0.0 44819000.0 62844000.0 +DDT 72443000.0 15724000.0 158000000.0 195050000.0 +MPP1 79367000.0 62097000.0 81639000.0 81916000.0 +GIMAP8 569570000.0 711840000.0 447260000.0 568070000.0 +GIMAP4 6520446000.0 7922436000.0 13524172000.0 14720990000.0 +GIMAP5 19548000.0 26506000.0 31299000.0 34710000.0 +GIMAP7 612990000.0 738750000.0 1109960000.0 1121780000.0 +GPHN 87636000.0 27092000.0 54533000.0 50303000.0 +LMNB2 371870000.0 414900000.0 252760000.0 289670000.0 +ENSBTAG00000010033 47201000.0 48244000.0 76667000.0 83343000.0 +ALDH4A1 6445900000.0 6948600000.0 7366100000.0 7514900000.0 +GSTT2 27221000000.0 27605000000.0 31963000000.0 33600000000.0 +TOLLIP 622970000.0 523460000.0 803230000.0 905730000.0 +MRPS26 91296000.0 110220000.0 104630000.0 109180000.0 +WARS 179490000.0 157360000.0 236000000.0 280770000.0 +MRPS25 91066000.0 78235000.0 67418000.0 74638000.0 +MRPS22 200830000.0 172840000.0 188640000.0 206580000.0 +MRPS23 262860000.0 243840000.0 190430000.0 193840000.0 +LAMTOR1 36993000.0 37027000.0 34751000.0 0.0 +LCMT1 82577000.0 76579000.0 95408000.0 111650000.0 +RASIP1 80363000.0 34553000.0 18803000.0 28381000.0 +EARS2 11696000.0 11436000.0 12182000.0 16286000.0 +ACTC1 372860000.0 368380000.0 179340000.0 256850000.0 +NAMPT 94309000.0 112770000.0 105540000.0 93040000.0 +ENSBTAG00000016032 446200000.0 369200000.0 332440000.0 299340000.0 +CTNND1 228550000.0 84502000.0 136920000.0 136970000.0 +GAREM1 38963000.0 0.0 5444900.0 5739700.0 +SH3GL1 20737000.0 18150000.0 31160000.0 21925000.0 +A2M 1054300000.0 1104000000.0 1471000000.0 1591700000.0 +OPTN 4585900.0 5984600.0 0.0 0.0 +BHMT 22120000000.0 20705000000.0 10381000000.0 10097000000.0 +THOP1 872630000.0 1109900000.0 659920000.0 657780000.0 +GOLGA2 6445000.0 0.0 2439900.0 0.0 +TTC24 0.0 0.0 0.0 140660000.0 +FTL 2607400000.0 2738200000.0 1826100000.0 2077500000.0 +VARS2 2585000.0 0.0 4548200.0 4510200.0 +FHL1 34958000.0 32920000.0 34106000.0 42464000.0 +DCXR 23207411000.0 21575405000.0 20072545000.0 20438960000.0 +FTH1 326120000.0 429230000.0 225920000.0 170550000.0 +UGGT2 0.0 0.0 0.0 0.0 +UGGT1 24549000.0 24915000.0 23915000.0 31228000.0 +RPS25 115990000.0 55709000.0 111490000.0 83904000.0 +APPL2 23145000.0 42928000.0 37342000.0 26820000.0 +ALDH7A1 1527800000.0 1555300000.0 1480800000.0 1455800000.0 +TOMM70 247440000.0 259600000.0 207700000.0 204840000.0 +MEMO1 312480000.0 308550000.0 351630000.0 359970000.0 +NT5DC1 15482000.0 11019000.0 13634000.0 9957900.0 +PPIF 3575400000.0 3694500000.0 2904800000.0 2797800000.0 +PPIE 324850000.0 411170000.0 270800000.0 253580000.0 +PPID 8480900.0 9943000.0 5043500.0 0.0 +SIGMAR1 92364000.0 121460000.0 213710000.0 160460000.0 +PPIA 1076400000.0 1097900000.0 983090000.0 1002600000.0 +SARS2 146510000.0 172940000.0 159610000.0 148820000.0 +SIRT3 1612100000.0 1720500000.0 1822700000.0 1646900000.0 +CYFIP1 83240000.0 8625300.0 15945000.0 17307000.0 +SNTB1 207830000.0 210450000.0 192310000.0 232880000.0 +HYI 522160000.0 562130000.0 767220000.0 714750000.0 +AIMP2 1236000000.0 1216600000.0 1073800000.0 1111200000.0 +KIAA0408 9072500.0 0.0 8682100.0 10002000.0 +AIMP1 84807000.0 103640000.0 53911000.0 69457000.0 +CORO1B 792030000.0 812400000.0 857800000.0 951080000.0 +CORO1C 546000000.0 563920000.0 671770000.0 639960000.0 +CORO1A 175350000.0 215620000.0 232520000.0 298110000.0 +ZBTB8OS 47651000.0 58223000.0 73723000.0 52760000.0 +MDH2 72975000000.0 76495000000.0 57739000000.0 51023000000.0 +MDH1 9057000000.0 9091700000.0 9152100000.0 9559200000.0 +MOXD1 4323500.0 0.0 0.0 0.0 +DDX3X 149900000.0 146870000.0 120840000.0 114870000.0 +TTPAL 30723000.0 34623000.0 19484000.0 22327000.0 +DCPS 9541100.0 18373000.0 6728900.0 9067600.0 +THUMPD3 10215000.0 9120700.0 9818300.0 10724000.0 +KYNU 146160000.0 170370000.0 177880000.0 206970000.0 +LHPP 1966000000.0 1888700000.0 1950700000.0 1944600000.0 +UVRAG 0.0 0.0 10180000.0 0.0 +SMARCA5 4099400.0 0.0 1812700.0 1688600.0 +FAH 4024200000.0 4203100000.0 2853600000.0 2842500000.0 +COPG2 1687800.0 0.0 0.0 4863700.0 +HNRNPA2B1 16098000000.0 16049000000.0 12679000000.0 14442000000.0 +COPG1 880400000.0 79820000.0 631490000.0 490520000.0 +CYP4A22 0.0 0.0 0.0 0.0 +NBAS 2055200.0 0.0 0.0 0.0 +PDZK1 361699000.0 398792000.0 216866000.0 207549000.0 +RENBP 33928000.0 33811000.0 30852000.0 34911000.0 +ENSBTAG00000001851 195620000.0 193290000.0 273230000.0 242800000.0 +SORT1 5271000.0 0.0 3576600.0 4655400.0 +GTPBP1 5051500.0 0.0 11203000.0 11029000.0 +NIF3L1 61108000.0 75349000.0 112840000.0 56148000.0 +GTPBP3 6836500.0 6714800.0 7100000.0 5884000.0 +GTPBP2 49330000.0 46109000.0 41825000.0 34104000.0 +HELLS 1716800.0 4645500.0 4976700.0 0.0 +CASP6 733920000.0 773920000.0 1093400000.0 1063300000.0 +UPP2 2415172000.0 2184720000.0 2086728000.0 2110034000.0 +SNRNP40 44366000.0 64544000.0 39208000.0 50883000.0 +BPNT1 146870000.0 141160000.0 219050000.0 267980000.0 +SHTN1 11868000.0 10959000.0 12066000.0 11188000.0 +ENSBTAG00000031738 4955700000.0 4662400000.0 4982600000.0 5856200000.0 +CASP8 12698000.0 12299000.0 13057000.0 15284000.0 +PURB 122270000.0 166300000.0 146000000.0 135950000.0 +PURA 131120000.0 113530000.0 125800000.0 133910000.0 +CFDP2 295360000.0 285400000.0 218890000.0 157310000.0 +EIF4A2 402540000.0 464500000.0 268960000.0 291670000.0 +PICALM 266490000.0 381600000.0 283080000.0 269320000.0 +HECTD3 8597200.0 0.0 14832000.0 19956000.0 +HECTD1 4589200.0 0.0 7373000.0 0.0 +ADPRHL2 270990000.0 293080000.0 287090000.0 314870000.0 +MAN2B1 3659400000.0 3957900000.0 4246200000.0 4066400000.0 +DARS 271920000.0 271780000.0 287600000.0 295260000.0 +LYPLA1 3915200000.0 3599900000.0 3753400000.0 3721800000.0 +NPEPL1 16461000.0 25302000.0 23582000.0 35160000.0 +CLMN 1200800.0 0.0 0.0 0.0 +CCS 96978000.0 111940000.0 111010000.0 104750000.0 +GLRX3 684860000.0 818690000.0 762600000.0 850230000.0 +AKT2 0.0 0.0 21789000.0 12819000.0 +LRFN4 20893000.0 19244000.0 51829000.0 104400000.0 +UPB1 2235500000.0 2118100000.0 1905500000.0 1644800000.0 +MRC1 3851800.0 0.0 0.0 0.0 +AHCYL2 93784000.0 100360000.0 45671000.0 73248000.0 +STUB1 357570000.0 354430000.0 333720000.0 332870000.0 +GRK2 105630000.0 110540000.0 118340000.0 181440000.0 +OTC 51295000000.0 53739000000.0 60054000000.0 61494000000.0 +CAPN5 9980800.0 0.0 5926700.0 5973000.0 +FLII 9828400.0 7593200.0 6604900.0 10570000.0 +CAPN2 176250000.0 4055200.0 23929000.0 33769000.0 +CAPN1 76448000.0 22145000.0 84894000.0 73600000.0 +PIR 47049000.0 37347000.0 66380000.0 45415000.0 +SEPT11 62722000.0 32852000.0 60561000.0 65773000.0 +SEPT10 37968000.0 37904000.0 39614000.0 38917000.0 +ENTPD5 652680000.0 585850000.0 558120000.0 521520000.0 +SPAG9 6473900.0 0.0 0.0 0.0 +COG3 1191200.0 0.0 4382000.0 4733000.0 +SMS 132670000.0 159860000.0 209480000.0 224030000.0 +P4HB 21324000000.0 21186000000.0 16337000000.0 17604000000.0 +CHTOP 166280000.0 212130000.0 127540000.0 135390000.0 +COG7 2448800.0 0.0 2248800.0 2198100.0 +SARAF 615090000.0 584540000.0 705440000.0 620540000.0 +ENTPD8 17127000.0 14952000.0 12837000.0 6618900.0 +OSTF1 444720000.0 323200000.0 438780000.0 440380000.0 +SERPINB1 209490000.0 158450000.0 692010000.0 707990000.0 +SERPINB2 3356000.0 0.0 0.0 0.0 +SERPINB4 0.0 0.0 179570000.0 96372000.0 +SERPINB6 1595600000.0 1623200000.0 1283100000.0 1422500000.0 +NFS1 146560000.0 176670000.0 145640000.0 151330000.0 +ENSBTAG00000048257 44965000.0 26241000.0 14271000.0 16695000.0 +UBC 8559600000.0 9490600000.0 9685800000.0 9964400000.0 +ELP2 6900700.0 0.0 0.0 3652200.0 +ELP1 0.0 0.0 7100800.0 7265000.0 +SPC24 41090000.0 71657000.0 19140000.0 0.0 +NRDC 4432300.0 0.0 0.0 0.0 +METAP1 6508700.0 5263200.0 0.0 0.0 +DES 610300000.0 624370000.0 830150000.0 935870000.0 +MSH2 12815000.0 5874800.0 12610000.0 18794000.0 +DCTN2 16588000.0 18958000.0 19313000.0 16854000.0 +AKR1A1 27258000000.0 24310000000.0 36807000000.0 34138000000.0 +SPRYD4 165880000.0 113550000.0 133890000.0 104040000.0 +ST13 184500000.0 153190000.0 281180000.0 337300000.0 +PTGFRN 160840000.0 7553400.0 61950000.0 56245000.0 +PLXNB2 88070000.0 38354000.0 60390000.0 50817000.0 +TRIM56 2132800.0 0.0 1594800.0 0.0 +TCTN3 258630000.0 196890000.0 261910000.0 221710000.0 +DDX6 31389000.0 29804000.0 40816000.0 37737000.0 +ENSBTAG00000022590 201950000.0 188470000.0 251240000.0 299460000.0 +HDDC3 313060000.0 406470000.0 583910000.0 463690000.0 +CMAS 183230000.0 137340000.0 116280000.0 104750000.0 +LANCL1 1017900000.0 1155500000.0 1416000000.0 1394600000.0 +PCBP2 835500000.0 898470000.0 1085300000.0 885340000.0 +PCBP1 4102600000.0 3954200000.0 2917500000.0 2997600000.0 +GBA3 2720000000.0 2928800000.0 3499100000.0 3411500000.0 +NPEPPS 147920000.0 7619700.0 66604000.0 69623000.0 +AMT 392590000.0 401670000.0 235680000.0 280700000.0 +SMC1A 4283000.0 0.0 0.0 0.0 +SIRT2 902880000.0 1037100000.0 929700000.0 837500000.0 +RAB7A 2354300000.0 2444000000.0 2423500000.0 2654300000.0 +NR4A1 0.0 0.0 0.0 0.0 +GNPNAT1 330660000.0 355410000.0 270860000.0 323810000.0 +SIRT5 1348100000.0 1308200000.0 1413600000.0 1401600000.0 +NDUFV2 375970000.0 345210000.0 549670000.0 551030000.0 +SGTA 291230000.0 299840000.0 402800000.0 435080000.0 +TMEM11 117870000.0 121370000.0 135000000.0 102430000.0 +TRIM47 18786000.0 3695400.0 4662400.0 5107300.0 +PLEK 21131000.0 12597000.0 19038000.0 18638000.0 +KIF3A 2949100.0 0.0 0.0 3145500.0 +PEX1 28072000.0 0.0 4991700.0 6960000.0 +HADH 56928000000.0 54954000000.0 38624000000.0 37434000000.0 +PEX5 4546500.0 0.0 5339000.0 9016200.0 +PEX6 14323000.0 0.0 5569500.0 4634400.0 +TKFC 3889200000.0 4322200000.0 5484100000.0 5520400000.0 +NWD2 0.0 0.0 4221900.0 4472400.0 +RBM25 1853500.0 0.0 4594600.0 4698500.0 +PPP2R1A 615130000.0 475210000.0 594520000.0 546420000.0 +ENSBTAG00000012692 119090000.0 150560000.0 198930000.0 153610000.0 +ATP5S 80615000.0 58300000.0 37874000.0 27685000.0 +ENSBTAG00000026812 530750000.0 161870000.0 419390000.0 425720000.0 +STAMBP 53207000.0 57120000.0 84763000.0 51072000.0 +NEB 10814000.0 0.0 13423000.0 287030000.0 +APOOL 528780000.0 481620000.0 490450000.0 417420000.0 +HNRNPH1 705390000.0 760280000.0 636750000.0 652400000.0 +HNRNPH3 116020000.0 170780000.0 151620000.0 128700000.0 +HNRNPH2 91756000.0 121390000.0 68973000.0 43704000.0 +PLRG1 0.0 26059000.0 22865000.0 18683000.0 +GNAI2 2837600000.0 2698800000.0 3478700000.0 3104000000.0 +GNAI3 423940000.0 446010000.0 666540000.0 531530000.0 +GNAI1 36702000.0 25732000.0 52118000.0 45727000.0 +MRPS34 47158000.0 60322000.0 37906000.0 24547000.0 +AFMID 479880000.0 536270000.0 697040000.0 735510000.0 +MRPS30 0.0 0.0 0.0 0.0 +HSPA12B 8022300.0 8874500.0 12752000.0 10881000.0 +STRN3 3389200.0 0.0 0.0 0.0 +ABHD16A 19047000.0 17955000.0 20742000.0 21030000.0 +MTHFR 1841100.0 0.0 15728000.0 14416000.0 +MTHFS 1068800000.0 1210200000.0 1054700000.0 1079800000.0 +PDSS2 13400000.0 13987000.0 5631400.0 6754100.0 +DTNB 0.0 13352000.0 12456000.0 14809000.0 +VCAM1 4752600.0 9958500.0 16303000.0 18328000.0 +PREP 101480000.0 59978000.0 158610000.0 162270000.0 +SYNE1 0.0 0.0 0.0 4429400.0 +SYNE3 9949100.0 12678000.0 16331000.0 20042000.0 +GOPC 24654000.0 24230000.0 219180000.0 33116000.0 +HNRNPUL1 12692000.0 10346000.0 3122100.0 5019500.0 +YTHDC1 4666600.0 0.0 0.0 0.0 +PCMT1 574170000.0 473220000.0 847370000.0 1172600000.0 +BSG 715560000.0 516320000.0 1008200000.0 894830000.0 +CNTLN 83002000.0 0.0 0.0 0.0 +DCHS1 0.0 0.0 550520000.0 0.0 +STOML2 1444300000.0 1811600000.0 1754100000.0 1894500000.0 +PDE4DIP 70217000.0 87860000.0 63303000.0 58188000.0 +ADA 733740000.0 778290000.0 762810000.0 773360000.0 +VPS16 11926000.0 0.0 6078100.0 0.0 +EP400 41899000.0 0.0 33587000.0 32396000.0 +RNH1 374310000.0 385710000.0 283330000.0 307100000.0 +RPS13 53552000.0 52299000.0 38297000.0 54888000.0 +CLPX 51022000.0 53789000.0 52208000.0 35238000.0 +RPS11 2050000000.0 2181500000.0 719190000.0 582020000.0 +RPS10 972550000.0 963850000.0 504090000.0 369130000.0 +RPS17 4413300000.0 5015000000.0 2341900000.0 2503800000.0 +RPS16 51607000.0 43867000.0 38571000.0 29380000.0 +RPS14 173000000.0 252610000.0 222780000.0 240580000.0 +ARL1 57347000.0 50909000.0 43345000.0 37487000.0 +CLPP 327050000.0 396390000.0 324780000.0 290900000.0 +RPS19 74594000.0 81296000.0 91809000.0 105780000.0 +CCDC22 22932000.0 0.0 0.0 1712500.0 +CCDC25 179030000.0 160030000.0 159340000.0 180580000.0 +FIBP 32611000.0 51232000.0 58892000.0 67641000.0 +ALDH3B1 1803800000.0 1739900000.0 1843500000.0 2069800000.0 +DCAF11 17731000.0 23010000.0 23699000.0 22160000.0 +DDOST 545390000.0 570530000.0 537010000.0 453090000.0 +MGC152281 557640000.0 569870000.0 721230000.0 754790000.0 +RRM1 13024000.0 0.0 6190300.0 6542500.0 +CLPB 34110000.0 35020000.0 36136000.0 36429000.0 +PUSL1 0.0 56005000.0 0.0 0.0 +DERA 3641400000.0 3319200000.0 3690800000.0 4214400000.0 +BROX 9319600.0 12444000.0 8118700.0 8757700.0 +TXN 21594000.0 0.0 26220000.0 144880000.0 +PAPSS2 715820000.0 663540000.0 478190000.0 595530000.0 +SLC9A3R2 99779000.0 157850000.0 89244000.0 99014000.0 +SLC9A3R1 609397600.0 668495400.0 624548400.0 700310000.0 +UBQLN1 42306000.0 42339000.0 77342000.0 77462000.0 +LSM12 130360000.0 147130000.0 104930000.0 123540000.0 +GCLC 18076000.0 20110000.0 16502000.0 15385000.0 +CASP7 317640000.0 309820000.0 404910000.0 382470000.0 +TF 171811000.0 105965000.0 170761000.0 157210000.0 +CYP2C18 464500000.0 607670000.0 762470000.0 835030000.0 +OAS1Y 30693000.0 28108000.0 13733000.0 14962000.0 +OAS1X 363200000.0 468150000.0 352220000.0 394300000.0 +TFAM 589950000.0 692400000.0 813680000.0 749750000.0 +TXNL1 1644300000.0 1455900000.0 1375300000.0 1334100000.0 +SSSCA1 23451000.0 25538000.0 0.0 17865000.0 +ENSBTAG00000000229 76348000.0 67270000.0 71280000.0 84392000.0 +GGT1 257060000.0 273170000.0 333610000.0 320620000.0 +TMX1 747730000.0 885280000.0 822000000.0 886890000.0 +NAGA 52725000.0 45252000.0 29319000.0 31871000.0 +NAGK 43969000.0 61140000.0 67062000.0 73778000.0 +ACTN2 9952900.0 0.0 3457400.0 0.0 +ACTN1 569180000.0 277130000.0 245470000.0 240630000.0 +CYP4A11 2275300000.0 2183500000.0 2032900000.0 2027000000.0 +ACTN4 3497200000.0 1229100000.0 1791600000.0 1941100000.0 +EZR 255700000.0 19718000.0 295630000.0 227620000.0 +GLYAT 2.2364e+11 2.0025e+11 1.5191e+11 1.3174e+11 +G3BP2 27139000.0 26798000.0 33032000.0 36041000.0 +PTPRM 8227600.0 0.0 0.0 0.0 +MYO7B 0.0 0.0 0.0 0.0 +STK10 5390100.0 4661200.0 0.0 0.0 +FKBP4 541680000.0 560730000.0 563180000.0 602130000.0 +SRSF10 514140000.0 492330000.0 565490000.0 520530000.0 +SEC23IP 64151000.0 42028000.0 58825000.0 98144000.0 +FKBP3 1186600000.0 1319000000.0 1254100000.0 1408300000.0 +FKBP8 51378000.0 78727000.0 115900000.0 89603000.0 +GAPVD1 53472000.0 73206000.0 70446000.0 120760000.0 +SGPL1 9431300.0 27854000.0 18613000.0 20251000.0 +NDUFB8 254190000.0 210980000.0 143200000.0 126090000.0 +PPME1 21684000.0 24815000.0 14152000.0 19079000.0 +MANF 286530000.0 286440000.0 139370000.0 126130000.0 +HEBP1 4319100000.0 4575200000.0 7177000000.0 6718200000.0 +HBS1L 28500000.0 13336000.0 16037000.0 16793000.0 +VAC14 74315000.0 35246000.0 78327000.0 69729000.0 +WDR5 90033000.0 77185000.0 112110000.0 98267000.0 +MAN2C1 0.0 0.0 0.0 0.0 +WDR1 509390000.0 549880000.0 506910000.0 528810000.0 +ZFYVE21 52572000.0 80923000.0 63792000.0 116730000.0 +APRT 1481800000.0 1601000000.0 1429700000.0 1302900000.0 +CSNK1A1 41405000.0 45183000.0 55643000.0 54308000.0 +ABLIM1 24298000.0 30745000.0 35816000.0 30282000.0 +JCHAIN 148620000.0 177090000.0 172050000.0 219710000.0 +SULT1E1 302150000.0 359680000.0 357020000.0 388660000.0 +L2HGDH 46199000.0 39565000.0 27411000.0 14522000.0 +SNAP23 66970000.0 51918000.0 63462000.0 77367000.0 +TOP2B 848310.0 0.0 0.0 0.0 +GM2A 71260000.0 77260000.0 77265000.0 92771000.0 +LACTB 88309000.0 100760000.0 121250000.0 115750000.0 +CSRP1 250440000.0 236990000.0 572850000.0 554550000.0 +CSRP2 31487000.0 37792000.0 77162000.0 68822000.0 +SUCLA2 11206000.0 13604000.0 0.0 9781500.0 +HHIP 2319500.0 0.0 0.0 0.0 +HSD17B12 258570000.0 282110000.0 460290000.0 423990000.0 +HSD17B13 86389000000.0 87613000000.0 94315000000.0 95872000000.0 +HSD17B10 1.662e+11 1.4555e+11 1.5148e+11 1.5949e+11 +20ALPHA-HSD 177990000.0 231600000.0 291200000.0 362590000.0 +ATP6V1A 105230000.0 130110000.0 105010000.0 120580000.0 +HSD17B14 2476000000.0 2450600000.0 2568200000.0 2983100000.0 +BBOX1 1907300000.0 2058700000.0 2389500000.0 2614800000.0 +EMD 181900000.0 173000000.0 273880000.0 301920000.0 +ATP6V1E1 235810000.0 245280000.0 287180000.0 278560000.0 +UOX 1162700000.0 1254500000.0 1838500000.0 1812200000.0 +ATP6V1H 8766500.0 9134000.0 11867000.0 12336000.0 +RAB6B 1420100000.0 1492800000.0 1449100000.0 1310800000.0 +MX1 2218300.0 0.0 18035000.0 15739000.0 +SFXN5 148090000.0 102920000.0 128200000.0 143170000.0 +SFXN2 457760000.0 415760000.0 376950000.0 392850000.0 +SFXN1 13866000000.0 12897000000.0 10756000000.0 12038000000.0 +UROD 1776200000.0 1899400000.0 1431300000.0 1669500000.0 +IFIT5 48904000.0 44297000.0 51053000.0 36661000.0 +LMO7 76731000.0 77792000.0 59847000.0 61464000.0 +CCT8 1277900000.0 1275600000.0 1300600000.0 1337600000.0 +ENSBTAG00000032453 1024300000.0 1249300000.0 1678600000.0 1528700000.0 +CCT2 842750000.0 836740000.0 910820000.0 765340000.0 +CCT3 681290000.0 685820000.0 638380000.0 668430000.0 +CCT7 691210000.0 768160000.0 749400000.0 833560000.0 +CCT4 1139600000.0 1022000000.0 1020400000.0 1115200000.0 +CCT5 661777000.0 786885000.0 697410000.0 708990000.0 +EFTUD2 63447000.0 14132000.0 31781000.0 27269000.0 +C4A 2683500.0 0.0 5047300.0 4945400.0 +ENSBTAG00000026133 0.0 0.0 0.0 1307300.0 +C14H8orf82 261800000.0 269680000.0 274300000.0 252230000.0 +PDLIM5 667980000.0 879930000.0 879870000.0 866960000.0 +PDLIM1 693510000.0 766260000.0 861740000.0 983630000.0 +PDLIM3 24464000.0 24396000.0 41071000.0 31825000.0 +BRCC3 145110000.0 133520000.0 170560000.0 170700000.0 +AKTIP 14386000.0 17852000.0 16217000.0 0.0 +ENSBTAG00000048287 91122000.0 110550000.0 174000000.0 144370000.0 +RAP1GDS1 222930000.0 164390000.0 327320000.0 387160000.0 +GDI2 2954800000.0 2703400000.0 2691500000.0 2596500000.0 +DHRS1 16786000000.0 16823000000.0 13378000000.0 14514000000.0 +GDI1 207740000.0 188400000.0 189740000.0 205500000.0 +MCCC2 1180000000.0 1203000000.0 1090500000.0 1176400000.0 +MCCC1 479860000.0 199200000.0 272440000.0 296780000.0 +PAFAH2 26890000.0 29125000.0 18514000.0 13953000.0 +ERLIN2 2578900000.0 2626300000.0 2326900000.0 2312200000.0 +GFM1 91462000.0 22034000.0 62233000.0 80288000.0 +GFM2 13191000.0 0.0 9623700.0 12104000.0 +CBS 331710000.0 405290000.0 299320000.0 343850000.0 +ENSBTAG00000034850 0.0 38902000.0 38575000.0 52146000.0 +FLNB 440460000.0 178120000.0 238220000.0 488900000.0 +EIF4A1 1291800000.0 1381800000.0 566150000.0 615320000.0 +EIF4A3 41238000.0 39590000.0 34954000.0 28141000.0 +KRT18 22250000000.0 23937000000.0 24904000000.0 26564000000.0 +CAPNS1 871780000.0 806020000.0 1008500000.0 1021700000.0 +CROT 2659100000.0 2615200000.0 2044900000.0 2005700000.0 +LETM1 95938000.0 14092000.0 63193000.0 64186000.0 +TMPRSS3 0.0 126060000.0 77770000.0 0.0 +PRKCSH 426160000.0 47167000.0 197520000.0 203480000.0 +TAF15 22299000.0 17855000.0 14406000.0 24872000.0 +FH 2269200000.0 2490900000.0 2614700000.0 2638000000.0 +DCTN3 521710000.0 498800000.0 418570000.0 578860000.0 +DCTN1 22437000.0 7038500.0 25766000.0 12439000.0 +RNASET2 212930000.0 311820000.0 208530000.0 215590000.0 +NDUFV3 68075000.0 66336000.0 76613000.0 95977000.0 +PKLR 1112300000.0 1158400000.0 1773200000.0 1970100000.0 +NDUFV1 304650000.0 301060000.0 265320000.0 240840000.0 +RPS4Y1 5758600000.0 5550400000.0 4115100000.0 4909900000.0 +ASPA 66040000.0 66841000.0 76709000.0 75187000.0 +FAM186A 0.0 0.0 0.0 13677000.0 +ASPN 146030000.0 155720000.0 279990000.0 293980000.0 +SERF2 0.0 0.0 0.0 5681200.0 +ASPH 224830000.0 234750000.0 199970000.0 207430000.0 +CYP39A1 8395000.0 0.0 7533400.0 5251100.0 +RBM15 26794000.0 32039000.0 0.0 0.0 +RBM14 190730000.0 204760000.0 105400000.0 124930000.0 +PARVA 230050000.0 236840000.0 257510000.0 270800000.0 +GGH 256520000.0 238600000.0 239100000.0 239980000.0 +NEXN 0.0 0.0 0.0 0.0 +MVP 362850000.0 60114000.0 328010000.0 414310000.0 +LAMA2 5163900.0 0.0 6648900.0 6664400.0 +PSMD6 24954000.0 0.0 28822000.0 24165000.0 +LAMA5 90082000.0 44053000.0 95415000.0 106580000.0 +ARVCF 15518000.0 7490600.0 1484000.0 7006500.0 +NAT1 1399700000.0 1165000000.0 1847700000.0 1659500000.0 +QPCTL 10582000.0 14977000.0 12539000.0 12945000.0 +FAM96A 183380000.0 138430000.0 160790000.0 165700000.0 +ALDH9A1 674280000.0 869410000.0 990140000.0 1009600000.0 +BPHL 1125500000.0 992170000.0 1082600000.0 978050000.0 +GLO1 6141200000.0 6630200000.0 9284100000.0 7989500000.0 +MVK 334470000.0 322000000.0 629160000.0 427220000.0 +ASRGL1 185280000.0 180700000.0 187390000.0 181430000.0 +CMBL 6730800000.0 6854400000.0 8409200000.0 8764900000.0 +F7 20044000.0 19853000.0 15657000.0 17768000.0 +F9 83664000.0 109390000.0 61310000.0 73307000.0 +LSP1 15994000.0 12617000.0 32234000.0 29300000.0 +GSTZ1 14655000000.0 16114000000.0 15953000000.0 17280000000.0 +MARS 88118000.0 9877800.0 81274000.0 53420000.0 +TUBGCP2 1622400.0 0.0 0.0 0.0 +CUL3 6928200.0 0.0 11029000.0 9865000.0 +NBEAL1 4800300.0 0.0 10826000.0 10975000.0 +CFD 0.0 0.0 0.0 61208000.0 +VAV2 3681100.0 0.0 0.0 0.0 +PSMD9 404120000.0 365530000.0 484210000.0 420800000.0 +PSMD8 449450000.0 620000000.0 397420000.0 398250000.0 +PSMD5 117950000.0 120000000.0 119040000.0 156130000.0 +PSMD4 155190000.0 170780000.0 121050000.0 106790000.0 +PSMD7 290790000.0 268130000.0 162760000.0 130450000.0 +FLAD1 29684000.0 47204000.0 35544000.0 11192000.0 +PSMD1 201290000.0 26324000.0 109910000.0 121460000.0 +PSMD3 42419000.0 53347000.0 75063000.0 82834000.0 +PSMD2 303750000.0 206420000.0 302810000.0 218040000.0 +CTNNB1 128470000.0 21738000.0 102480000.0 101680000.0 +NGFR 4660200.0 0.0 0.0 0.0 +CPSF7 22101000.0 27438000.0 18554000.0 0.0 +MOB1A 80968000.0 86045000.0 62961000.0 60203000.0 +CPSF3 4819700.0 0.0 2513700.0 3079100.0 +CPSF2 12355000.0 0.0 0.0 0.0 +CPSF1 0.0 0.0 0.0 0.0 +EPS15 14692000.0 20334000.0 21062000.0 18323000.0 +QKI 49407000.0 35100000.0 45602000.0 66936000.0 +ENSBTAG00000014220 91830000.0 93167000.0 148960000.0 137590000.0 +MAD1L1 11499000.0 0.0 0.0 6970700.0 +CATHL2 264870000.0 275800000.0 1099600000.0 1005200000.0 +CATHL3 35131000.0 43219000.0 367880000.0 353550000.0 +CATHL1 52952000.0 47811000.0 97534000.0 102780000.0 +HSD17B8 5362300000.0 5608000000.0 4592700000.0 5121100000.0 +HMGCL 4501300000.0 5242700000.0 4685300000.0 5195300000.0 +ACAA1 14126000000.0 15236000000.0 12981000000.0 12920000000.0 +ILVBL 400130000.0 433190000.0 503800000.0 520350000.0 +CNOT7 66502000.0 56477000.0 34253000.0 35471000.0 +HSD17B6 12351000000.0 12042000000.0 20767000000.0 20932000000.0 +HSD17B7 819430000.0 856740000.0 1351200000.0 1350900000.0 +ITGB1 159000000.0 5402500.0 53231000.0 59428000.0 +ITGB3 36181000.0 0.0 2942500.0 2632500.0 +ENSBTAG00000039289 266550000.0 255220000.0 312160000.0 348370000.0 +ITGB5 4616100.0 0.0 5805400.0 5596900.0 +ITGB6 8678600.0 0.0 13554000.0 0.0 +RTN4 2998500.0 7860500.0 8646500.0 43422000.0 +HAX1 17560000.0 18992000.0 18092000.0 16648000.0 +KPNB1 468780000.0 19149000.0 188070000.0 148720000.0 +HGS 6456800.0 2900500.0 0.0 1583900.0 +R3HDM1 0.0 0.0 0.0 0.0 +MST1 3544800.0 0.0 0.0 0.0 +HGD 9350000000.0 9826300000.0 10338000000.0 10131000000.0 +PRMT5 664950.0 0.0 0.0 0.0 +COPS7B 80421000.0 25712000.0 82350000.0 84168000.0 +COPS7A 376950000.0 439990000.0 352550000.0 362020000.0 +CRAT 937510000.0 953140000.0 837990000.0 823690000.0 +PPFIA1 1257700.0 0.0 0.0 0.0 +MYO6 8065100.0 0.0 22000000.0 31960000.0 +RABGGTB 89700000.0 107540000.0 110640000.0 107890000.0 +NAP1L4 12128000.0 13242000.0 11755000.0 10763000.0 +KIF13B 3597700.0 0.0 0.0 0.0 +RABGGTA 10909000.0 10594000.0 11334000.0 9474100.0 +ENSBTAG00000019601 34380000.0 39797000.0 27628000.0 28720000.0 +FSHB 7739200.0 0.0 7583300.0 6911400.0 +ENSBTAG00000044137 0.0 0.0 0.0 61369000.0 +HUWE1 35663000.0 0.0 49643000.0 15985000.0 +MAT1A 2752000000.0 2761900000.0 2424600000.0 3007500000.0 +EHD4 90108000.0 74856000.0 68414000.0 87003000.0 +PKP2 181330000.0 271840000.0 187080000.0 189640000.0 +EHD3 638510000.0 663950000.0 546150000.0 484830000.0 +SLC25A15 1432900000.0 1717300000.0 1186700000.0 1081700000.0 +SLC25A13 5389300.0 5656600.0 5559500.0 0.0 +SLC25A12 0.0 0.0 0.0 0.0 +SLC25A11 1441800000.0 1491900000.0 1532800000.0 1535300000.0 +PEBP1 25712000000.0 22913000000.0 33230000000.0 32581000000.0 +ACAA2 39992000000.0 40136000000.0 29003000000.0 27706000000.0 +CNOT9 46751000.0 55376000.0 43803000.0 52149000.0 +NDUFA10 685240000.0 746010000.0 751540000.0 728560000.0 +FGG 3701700000.0 3937600000.0 5071600000.0 5600200000.0 +METTL7A 77720000.0 140140000.0 134380000.0 122100000.0 +METTL7B 42381000000.0 38075000000.0 46410000000.0 53351000000.0 +TOR1AIP2 16648000.0 21520000.0 33596000.0 32846000.0 +PLBD2 467430000.0 476440000.0 521650000.0 511990000.0 +ACIN1 2569300.0 0.0 3345000.0 0.0 +ATP1B3 213660000.0 233490000.0 352570000.0 407660000.0 +LPP 48707000.0 72113000.0 56820000.0 42382000.0 +TNFRSF21 6167700.0 0.0 0.0 0.0 +PSMC2 409550000.0 407570000.0 470930000.0 447010000.0 +SYNCRIP 152230000.0 198680000.0 104310000.0 112560000.0 +FCGRT 363270000.0 483160000.0 388460000.0 436190000.0 +HSD17B4 47904000000.0 50286000000.0 52436000000.0 53262000000.0 +ALDH1L1 25332000000.0 9838100000.0 17083000000.0 20738000000.0 +MPV17L 50791000.0 95094000.0 15954000.0 7800400.0 +C1QC 103610000.0 107250000.0 114500000.0 106760000.0 +C1QB 209980000.0 165440000.0 262140000.0 246170000.0 +VIM 3926300000.0 4128400000.0 5853000000.0 6041200000.0 +EFL1 2856600.0 0.0 7274200.0 6343700.0 +TRA2B 484300000.0 496070000.0 411220000.0 452140000.0 +PHB 15985000000.0 15933000000.0 14559000000.0 16163000000.0 +MMAA 1352500000.0 1572900000.0 1779700000.0 1585200000.0 +ALDH5A1 1487600000.0 1489400000.0 1700900000.0 1830900000.0 +MMAB 1654500000.0 1766300000.0 2075900000.0 1757700000.0 +OSBP 428520000.0 265220000.0 187730000.0 176890000.0 +PTPN11 19019000.0 16365000.0 20393000.0 687930000.0 +DDAH2 359630000.0 357680000.0 422850000.0 475020000.0 +DIABLO 297480000.0 303310000.0 308250000.0 272710000.0 +SDR39U1 647830000.0 617860000.0 552030000.0 591450000.0 +SNX2 578520000.0 550310000.0 521130000.0 531050000.0 +PDXK 336240000.0 336910000.0 287390000.0 227620000.0 +CYB5R3 18540000000.0 16537000000.0 25042000000.0 26395000000.0 +SNX6 156050000.0 187170000.0 103590000.0 94271000.0 +CYB5R1 97616000.0 87402000.0 76542000.0 121300000.0 +SNX4 13815000.0 13045000.0 13681000.0 16818000.0 +UGT3A2 102390000.0 95136000.0 152750000.0 127000000.0 +SPTAN1 1147800000.0 373950000.0 643940000.0 625110000.0 +SNX9 41027000.0 59252000.0 38935000.0 57635000.0 +SPON1 8440200.0 0.0 0.0 8201500.0 +ALG5 62653000.0 58442000.0 63948000.0 80832000.0 +ITGB2 27198000.0 22826000.0 37216000.0 29875000.0 +MASP2 31078000.0 0.0 25379000.0 33242000.0 +PDXP 858860000.0 819780000.0 1036300000.0 947310000.0 +FUK 6615700.0 0.0 14818000.0 14564000.0 +CCDC127 94328000.0 123450000.0 115780000.0 113080000.0 +NOS3 3590500.0 14437000.0 0.0 0.0 +RAB11A 1991600000.0 2249400000.0 2029700000.0 1881300000.0 +GCC2 594960.0 0.0 0.0 0.0 +ENSBTAG00000046676 48550000.0 69465000.0 39650000.0 57079000.0 +PKM 257561000.0 261645000.0 306633000.0 266375000.0 +TMED7 835790000.0 932310000.0 672290000.0 680350000.0 +BLA-DQB 21763000.0 36572000.0 33903000.0 31517000.0 +CSK 30640000.0 31665000.0 37316000.0 41025000.0 +DAP3 22690000.0 21559000.0 25655000.0 26666000.0 +TNPO1 90346000.0 4736100.0 74437000.0 68664000.0 +EIF4E 220430000.0 300230000.0 246000000.0 213620000.0 +TELO2 12148000.0 0.0 4630400.0 3660700.0 +CALU 14441000.0 14244000.0 8392400.0 0.0 +TUBB2A 0.0 33716000.0 34336000.0 38766000.0 +TUBB2B 68642000.0 59808000.0 84258000.0 54872000.0 +PAAF1 31569000.0 28441000.0 37512000.0 37182000.0 +CD99 17962000.0 43054000.0 61204000.0 0.0 +COMTD1 18172000.0 18721000.0 11679000.0 12535000.0 +TUBB 699230000.0 646990000.0 567290000.0 505000000.0 +MAOB 11277000000.0 11786000000.0 10746000000.0 12257000000.0 +NAPRT 1570700000.0 1416600000.0 2024700000.0 2003500000.0 +DTYMK 447940000.0 418540000.0 254230000.0 235700000.0 +NEIL3 4165200.0 0.0 3392300.0 4049300.0 +ENSBTAG00000048275 800657000.0 804232000.0 952999000.0 915604000.0 +MUT 2304300000.0 1235200000.0 1726600000.0 1640800000.0 +INMT 446420000.0 232420000.0 145190000.0 153350000.0 +CLYBL 3550279000.0 3836427000.0 3564100000.0 3735583000.0 +RFC2 21130000.0 22319000.0 11434000.0 0.0 +PGAM5 949790000.0 898470000.0 802760000.0 816340000.0 +TECR 19389000.0 28373000.0 41910000.0 32385000.0 +FABP1 1412600000.0 1248700000.0 2425500000.0 2126800000.0 +AKR1C4 76362000000.0 90433000000.0 85571000000.0 70277000000.0 +CBX3 139270000.0 144060000.0 134780000.0 135410000.0 +LCP1 262450000.0 245330000.0 236000000.0 308880000.0 +FECH 319750000.0 376110000.0 317500000.0 357100000.0 +AKR1C3 1.017e+11 1.0931e+11 1.4652e+11 1.5405e+11 +ZBTB10 90706000.0 6285900.0 24843000.0 27192000.0 +SEH1L 19484000.0 17666000.0 0.0 19348000.0 +ENSBTAG00000008184 1650200000.0 1815000000.0 1312700000.0 1459900000.0 +CCDC51 109650000.0 130190000.0 163400000.0 188320000.0 +MRPL22 13524000.0 31727000.0 0.0 0.0 +C1QBP 106850000.0 176150000.0 115140000.0 80877000.0 +RAB18 1764900000.0 2089300000.0 1520400000.0 1432000000.0 +ENSBTAG00000018680 1282300.0 0.0 0.0 0.0 +TRAPPC11 2564400.0 0.0 13091000.0 12838000.0 +TRAPPC12 892000.0 0.0 0.0 0.0 +ENSBTAG00000047699 0.0 23767000.0 0.0 0.0 +RAB13 50773000.0 60555000.0 49456000.0 50840000.0 +SRP72 16433000.0 14733000.0 19372000.0 17076000.0 +RAB15 926950000.0 1102700000.0 1462400000.0 1369100000.0 +RAB14 5535700000.0 6435600000.0 5914900000.0 5779400000.0 +RAB17 14932000.0 15309000.0 15395000.0 16709000.0 +ASL 3952400000.0 4219400000.0 4383400000.0 4614200000.0 +RRAS2 863910000.0 793140000.0 959630000.0 779890000.0 +RAB1A 3093800000.0 3255700000.0 3498900000.0 2919000000.0 +NAGLU 17864000.0 0.0 8838100.0 25113000.0 +FYN 0.0 19205000.0 22333000.0 0.0 +GMPPA 297170000.0 275830000.0 198880000.0 196640000.0 +GMPPB 260290000.0 247220000.0 222020000.0 213150000.0 +ENSBTAG00000011330 551640000.0 472870000.0 318140000.0 286080000.0 +GNL1 4006900.0 0.0 2782800.0 3925300.0 +MTOR 1779700.0 0.0 0.0 0.0 +LAMP2 252180000.0 124500000.0 290720000.0 240700000.0 +ACADSB 20895000.0 28348000.0 22520000.0 28382000.0 +ALDH2 26150000000.0 25846000000.0 33588000000.0 34135000000.0 +PTPA 368780000.0 325710000.0 531010000.0 447250000.0 +SHOC2 215600000.0 231460000.0 84800000.0 85916000.0 +RPL10A 7105900000.0 6729600000.0 6670700000.0 6663700000.0 +RAD50 825210.0 0.0 0.0 0.0 +SEPT9 171480000.0 182550000.0 237690000.0 217310000.0 +PIP4P1 63096000.0 55017000.0 60643000.0 58816000.0 +USP8 1436300.0 0.0 1347300.0 0.0 +DDO 1051630000.0 1095370000.0 1424250000.0 1556720000.0 +USP4 4593700.0 0.0 0.0 0.0 +USP7 14138000.0 0.0 10256000.0 11462000.0 +RPRD1A 331490000.0 330780000.0 391730000.0 255150000.0 +MRPS15 24696000.0 28921000.0 20246000.0 24660000.0 +NUP37 12007000.0 9333000.0 10802000.0 18845000.0 +RNF31 360570.0 0.0 0.0 0.0 +COQ4 202260000.0 227590000.0 185860000.0 135080000.0 +ASAH1 140440000.0 146830000.0 310630000.0 252340000.0 +TPPP 57902000.0 53537000.0 106850000.0 83540000.0 +XRCC5 2772000.0 0.0 0.0 0.0 +BID 44864000.0 56484000.0 62319000.0 42804000.0 +PHKB 3676600.0 0.0 9364500.0 8701600.0 +PFKM 3724200.0 0.0 7122000.0 8272100.0 +PFKL 87787000.0 0.0 140350000.0 120400000.0 +QDPR 21128000000.0 19245000000.0 20589000000.0 20254000000.0 +PITPNB 461790000.0 437130000.0 612110000.0 560760000.0 +LMAN2L 70254000.0 62676000.0 92550000.0 131550000.0 +TTPA 1552600000.0 1241400000.0 1342000000.0 1372300000.0 +SND1 1459700000.0 1270300000.0 755680000.0 780930000.0 +TPP1 682970000.0 731230000.0 604190000.0 605200000.0 +TPP2 340190000.0 101450000.0 264160000.0 228690000.0 +PSME2 1489900000.0 1807900000.0 1707600000.0 1835300000.0 +PSME3 91765000.0 78561000.0 115470000.0 111240000.0 +PSME1 1717400000.0 1762600000.0 2569900000.0 2132400000.0 +SRSF6 59275000.0 67466000.0 100290000.0 105190000.0 +CUL5 14825000.0 3746200.0 6827500.0 6948600.0 +SLK 771150.0 0.0 0.0 0.0 +CIDEB 317680000.0 340030000.0 296290000.0 321110000.0 +CTNNA1 549040000.0 33126000.0 185030000.0 179460000.0 +CTNNA2 998140.0 0.0 30542000.0 13242000.0 +PHYH 7381900000.0 6930500000.0 6795200000.0 5994400000.0 +TAMM41 39948000.0 21162000.0 16393000.0 21088000.0 +ABCF1 41976000.0 0.0 21719000.0 19873000.0 +TOPBP1 3669100.0 0.0 0.0 0.0 +CLEC4G 160360000.0 163570000.0 157240000.0 185490000.0 +GSPT1 37664000.0 53827000.0 35029000.0 11117000.0 +SSR1 67042000.0 82735000.0 180780000.0 154180000.0 +SSR4 60152000.0 69130000.0 55690000.0 85881000.0 +TMEM33 40266000.0 44747000.0 52057000.0 49719000.0 +CNTRL 41156000.0 0.0 44410000.0 38086000.0 +SLF1 186380000.0 137090000.0 80350000.0 88024000.0 +GDA 264690000.0 263390000.0 380070000.0 446970000.0 +TM7SF2 178810000.0 140280000.0 266780000.0 289770000.0 +ADPGK 39968000.0 21227000.0 35039000.0 30031000.0 +MLEC 926030000.0 886520000.0 1716900000.0 1761400000.0 +TGM2 312630000.0 105940000.0 210220000.0 322130000.0 +BGN 5747200.0 0.0 2720100.0 2919900.0 +CASTOR1 285430000.0 407950000.0 651840000.0 655160000.0 +IST1 82810000.0 67184000.0 90333000.0 121040000.0 +RAPGEF1 30054000.0 0.0 200330000.0 227800000.0 +XDH 19766000.0 0.0 3890400.0 0.0 +ASPDH 3411200000.0 3744400000.0 4248500000.0 4001800000.0 +SELENBP1 8123800000.0 7795500000.0 11938000000.0 12859000000.0 +PARK7 8095000000.0 9412200000.0 10240000000.0 10160000000.0 +PRODH2 30926000.0 31076000.0 40897000.0 46306000.0 +RORC 352020000.0 0.0 0.0 0.0 +MPP6 136080000.0 106750000.0 73667000.0 70741000.0 +EML4 26866000.0 0.0 5985300.0 6239700.0 +TFRC 42903000.0 1534600.0 24988000.0 19314000.0 +NSFL1C 287620000.0 226100000.0 233050000.0 235900000.0 +TAGLN2 202160000.0 223180000.0 255200000.0 192880000.0 +GUSB 286452000.0 179470000.0 125880000.0 75764200.0 +GNPDA1 221430000.0 237310000.0 332770000.0 262800000.0 +PRPSAP1 32545000.0 30984000.0 24045000.0 17497000.0 +LAS1L 2197200.0 0.0 0.0 0.0 +ENSBTAG00000040134 13439000.0 11551000.0 40177000.0 112060000.0 +PRUNE1 24636000.0 18829000.0 30498000.0 21264000.0 +ETFDH 3518500000.0 3746000000.0 3225600000.0 3141500000.0 +SLC25A22 4573900000.0 5094200000.0 4754300000.0 5387800000.0 +SLC25A20 6567700000.0 6403600000.0 4486500000.0 4504100000.0 +ERO1A 51777000.0 73414000.0 48843000.0 54628000.0 +CFAP73 95913000.0 30724000.0 108970000.0 42958000.0 +SLC3A2 1556500.0 0.0 4036700.0 0.0 +GMPS 17641000.0 53838000.0 29957000.0 24794000.0 +ENSBTAG00000030384 62681000.0 150460000.0 13026000.0 107140000.0 +IKBKB 3645100.0 0.0 0.0 3025800.0 +ATIC 1463900000.0 1577300000.0 1687800000.0 1869500000.0 +PCTP 878140000.0 912010000.0 1116400000.0 866430000.0 +DHODH 271590000.0 258390000.0 244670000.0 260810000.0 +ENSBTAG00000046905 33754000.0 30891000.0 46408000.0 68161000.0 +KPNA6 0.0 0.0 25838000.0 0.0 +REXO2 134800000.0 118240000.0 147050000.0 122940000.0 +KPNA3 30780000.0 33423000.0 38521000.0 38178000.0 +KPNA2 8038500.0 21105000.0 3849900.0 3423800.0 +COPB1 363400000.0 56652000.0 187320000.0 239400000.0 +COPB2 233430000.0 81395000.0 127390000.0 101640000.0 +SEL1L 58488000.0 0.0 23751000.0 23988000.0 +UBE2N 64123000.0 74279000.0 101300000.0 74555000.0 +PTPMT1 13311000.0 11356000.0 14016000.0 17835000.0 +CRP 400110000.0 394520000.0 484060000.0 462730000.0 +PLCB1 34418000.0 0.0 0.0 0.0 +GORASP2 88387000.0 53118000.0 13313000.0 67499000.0 +CARM1 14440000.0 16580000.0 14201000.0 17424000.0 +CIAO1 16818000.0 12062000.0 14232000.0 22084000.0 +EXOC3L2 3269800.0 0.0 0.0 0.0 +TMEM177 40962000.0 27093000.0 28736000.0 32043000.0 +CRK 338600000.0 343810000.0 486080000.0 547430000.0 +EIF5B 25147000.0 2972400.0 5535100.0 9515600.0 +NUDT21 401550000.0 358920000.0 438540000.0 368960000.0 +EIF5A 546490000.0 478300000.0 136510000.0 291950000.0 +SUMF2 55881000.0 46413000.0 42227000.0 45629000.0 +NONO 101390000.0 127330000.0 98999000.0 119910000.0 +GLDC 909960000.0 279330000.0 431400000.0 368030000.0 +UNC45A 26330000.0 0.0 20115000.0 27295000.0 +PC 16755000000.0 8060000000.0 6060500000.0 6002200000.0 +RTN4IP1 282650000.0 262160000.0 300050000.0 313510000.0 +FNDC3A 8186000.0 0.0 0.0 6604700.0 +PGK1 3846700000.0 4153900000.0 2412900000.0 2519100000.0 +SULT1C4 12400000000.0 11685000000.0 8719100000.0 9321700000.0 +TUBB6 19910000.0 20654000.0 22843000.0 18861000.0 +DHRS11 1696800000.0 1758100000.0 1599700000.0 1517100000.0 +DHRS12 545750000.0 615250000.0 498050000.0 507130000.0 +ACSF3 82967000.0 60923000.0 101500000.0 88958000.0 +TUBB3 9054300.0 5466500.0 8428900.0 5727300.0 +MAN2A1 35954000.0 9905800.0 6133700.0 7325200.0 +RPP25L 50837000.0 61199000.0 50463000.0 51813000.0 +EEF1D 5022300000.0 5680500000.0 5375400000.0 5295700000.0 +SPACA6 0.0 0.0 0.0 0.0 +GALK1 3022500000.0 3012100000.0 2117100000.0 2196900000.0 +SH3BGRL3 73872000.0 0.0 0.0 0.0 +RPAP1 23613000.0 70312000.0 115630000.0 97181000.0 +PRPF19 37825000.0 39665000.0 40946000.0 45918000.0 +EIF3A 43766000.0 3553300.0 65440000.0 78429000.0 +GPD1L 25201000.0 37663000.0 23703000.0 31374000.0 +TMLHE 8287900.0 7133700.0 0.0 7044800.0 +EIF3B 103000000.0 6112700.0 50218000.0 38226000.0 +OXA1L 13987000.0 40108000.0 6671000.0 10835000.0 +TINAGL1 14317000.0 33653000.0 47543000.0 69276000.0 +EIF3E 76322000.0 80931000.0 46587000.0 48670000.0 +DDC 76879000.0 63251000.0 94560000.0 94206000.0 +DARS2 57325000.0 55495000.0 38114000.0 51614000.0 +RHOT1 8852400.0 0.0 4990100.0 8419800.0 +ARHGEF1 19179000.0 21207000.0 16996000.0 29976000.0 +TP53RK 503000000.0 523800000.0 487190000.0 469860000.0 +DNAAF5 35503000.0 37232000.0 55074000.0 49106000.0 +POFUT1 71799000.0 59515000.0 45066000.0 49801000.0 +STAT6 6931700.0 0.0 3030300.0 0.0 +LAMC1 6696000.0 8776100.0 0.0 0.0 +STAT3 293640000.0 354740000.0 159310000.0 256630000.0 +STAT2 36567000.0 35118000.0 10531000.0 16581000.0 +STAT1 82050000.0 108390000.0 155510000.0 160200000.0 +CD81 32301000.0 65261000.0 93587000.0 121200000.0 +ENSBTAG00000037605 23272000.0 22127000.0 30367000.0 23349000.0 +HPRT1 1554600000.0 1927100000.0 1281100000.0 1247800000.0 +USP19 1541600.0 0.0 0.0 0.0 +RPL13A 1853600000.0 2151400000.0 1746900000.0 1818000000.0 +ICAM1 6197400.0 0.0 5552400.0 5385200.0 +CYP7A1 125470000.0 100730000.0 49475000.0 48058000.0 +CTDSP1 0.0 22956000.0 26691000.0 26935000.0 +DPM1 812290000.0 854150000.0 648660000.0 773710000.0 +CRYAB 295960000.0 441530000.0 434730000.0 765690000.0 +CD68 24017000.0 3878200.0 6296000.0 7915600.0 +LMNB1 94612700.0 87258000.0 66640000.0 82345000.0 +TPD52L2 59415000.0 116940000.0 100030000.0 99381000.0 +MAIP1 135950000.0 148740000.0 176170000.0 124630000.0 +EFCAB11 200270000.0 179980000.0 185050000.0 172180000.0 +AKR1B1 505260000.0 497560000.0 648990000.0 790800000.0 +LRBA 7792500.0 0.0 23297000.0 29613000.0 +ENSBTAG00000037510 56623000.0 66507000.0 91987000.0 93652000.0 +SLBP2 0.0 0.0 0.0 0.0 +LRP1 103570000.0 18666000.0 30687000.0 40503000.0 +GSTT1 9622970000.0 8760550000.0 11908300000.0 12553900000.0 +ISOC1 3908400000.0 3766300000.0 3709900000.0 3859600000.0 +ARPC5L 135520000.0 164240000.0 279390000.0 279070000.0 +WDR13 48482000.0 53244000.0 36699000.0 0.0 +ATP5PD 2917900000.0 3334800000.0 3635300000.0 3491200000.0 +WDR11 0.0 0.0 0.0 0.0 +TMTC3 118920000.0 0.0 0.0 0.0 +RHEB 55905000.0 0.0 61047000.0 54597000.0 +STIM1 71143000.0 106670000.0 74968000.0 78189000.0 +CD276 1770800.0 0.0 3647400.0 3424900.0 +CREG1 862999000.0 721157000.0 1570010000.0 1633270000.0 +CDH17 40960000.0 209260000.0 29298000.0 25708000.0 +SPATA20 71267000.0 17384000.0 67358000.0 63115000.0 +ENSBTAG00000016472 68538000000.0 67296000000.0 1.4577e+11 1.5094e+11 +C8A 73567000.0 107180000.0 55628000.0 54803000.0 +USP9X 17399000.0 0.0 8239500.0 5391700.0 +GPD1 62098000000.0 56265000000.0 57407000000.0 58741000000.0 +MAP2K6 262040000.0 242890000.0 206250000.0 212000000.0 +MAP4 20375000.0 0.0 32554000.0 44631000.0 +MAP2K4 56386000.0 56810000.0 78206000.0 51191000.0 +AACS 0.0 0.0 2462200.0 2288000.0 +BCL9L 184120000.0 228080000.0 87008000.0 166030000.0 +MICU1 8180600.0 0.0 0.0 0.0 +TSNAX 52854000.0 44020000.0 62545000.0 42609000.0 +ENSBTAG00000048135 7596100000.0 7057900000.0 9843800000.0 10550300000.0 +COX2 2881100000.0 2034500000.0 1622700000.0 2043000000.0 +GAT 8595100000.0 8036900000.0 6933700000.0 7132400000.0 +MRPL18 29895000.0 39796000.0 13792000.0 0.0 +PPL 120960000.0 25649000.0 81002000.0 106750000.0 +APEX1 241440000.0 290870000.0 254290000.0 193590000.0 +ACY1 4267600000.0 3897600000.0 4004700000.0 3900700000.0 +KMT2C 34326000.0 59607000.0 45843000.0 50135000.0 +ITPA 73286000.0 54244000.0 60827000.0 65127000.0 +HSPB1 74536000000.0 63782000000.0 1.2829e+11 1.2019e+11 +COL18A1 452620000.0 527270000.0 298610000.0 332070000.0 +CYP4V2 201970000.0 208260000.0 251870000.0 271860000.0 +PKN2 0.0 95081000.0 33973000.0 24290000.0 +SUCLG2 3098200000.0 3059300000.0 1944500000.0 1959800000.0 +SUCLG1 5900200000.0 5648200000.0 5316700000.0 5819900000.0 +ENSBTAG00000021368 53939000.0 35884000.0 77103000.0 82457000.0 +DYNC1H1 109350000.0 35590000.0 60784000.0 55303000.0 +ALDOA 2074700000.0 2014700000.0 1191000000.0 1139300000.0 +ALDOC 42258000.0 23839000.0 21695000.0 0.0 +ALDOB 313550000.0 81383000.0 117810000.0 109250000.0 +ENSBTAG00000019437 4443500.0 0.0 0.0 2993400.0 +ENSBTAG00000046325 6019900.0 0.0 0.0 0.0 +DIS3L2 1482700.0 0.0 4869100.0 4948900.0 +IMPA1 153090000.0 177080000.0 152940000.0 166560000.0 +RAB30 27882000.0 26272000.0 14101000.0 20189000.0 +CYC1 2774800000.0 2991700000.0 2472800000.0 2895500000.0 +PON3 541890000.0 549370000.0 521820000.0 491840000.0 +PON2 109480000.0 101690000.0 63738000.0 57138000.0 +PSAT1 9977100000.0 10684000000.0 13686000000.0 14121000000.0 +CPNE3 139600000.0 160280000.0 200310000.0 173060000.0 +SPATA2L 12336000.0 0.0 0.0 2966100.0 +CMPK1 3057700000.0 2900400000.0 3025600000.0 2995100000.0 +HAO1 14077000000.0 12679000000.0 16286000000.0 16490000000.0 +HAO2 12887000000.0 13047000000.0 9921600000.0 11276000000.0 +CMPK2 6470300.0 6993500.0 6650600.0 9271800.0 +CKAP4 835660000.0 849250000.0 606150000.0 587120000.0 +EDEM3 3194500.0 0.0 0.0 1731600.0 +FAM213A 774150000.0 799570000.0 1209100000.0 1128500000.0 +GSS 285760000.0 267960000.0 351250000.0 373390000.0 +GSR 406380000.0 438930000.0 456640000.0 467730000.0 +MRPL2 138100000.0 117430000.0 52367000.0 74822000.0 +LRPPRC 132450000.0 0.0 136940000.0 139320000.0 +WASHC5 1252200.0 0.0 11694000.0 11853000.0 +PSMF1 304680000.0 196450000.0 219600000.0 228440000.0 +PPCDC 89014000.0 108650000.0 149690000.0 144310000.0 +AFG3L2 75593000.0 87184000.0 60569000.0 44647000.0 +SCO2 367310000.0 340910000.0 333880000.0 410440000.0 +SCO1 2159600000.0 2175200000.0 1850400000.0 2091100000.0 +PBXIP1 19017000.0 1821500.0 6024400.0 11059000.0 +UGP2 6024000000.0 6034600000.0 3775600000.0 4248100000.0 +HTATIP2 312500000.0 382280000.0 255650000.0 312110000.0 +MPST 2178500000.0 2338100000.0 2672800000.0 2722400000.0 +KHK 7678700000.0 7719300000.0 7810000000.0 8109500000.0 +GOLGA5 3346200.0 3413000.0 0.0 0.0 +APEH 472090000.0 21387000.0 210340000.0 206070000.0 +PTBP2 67267000.0 56472000.0 173780000.0 70403000.0 +PTBP1 1016600000.0 1283000000.0 894870000.0 1040700000.0 +NNT 440450000.0 463020000.0 249680000.0 221990000.0 +ENSBTAG00000038461 77886000.0 22533000.0 103280000.0 99644000.0 +BOLA 147600000.0 161720000.0 129670000.0 133910000.0 +ENPP6 12060000.0 10733000.0 11865000.0 13246000.0 +HK3 33321000.0 0.0 157920000.0 154700000.0 +HK1 9312600.0 0.0 8800400.0 6942300.0 +ENPP1 470280000.0 63057000.0 359790000.0 288310000.0 +ENSBTAG00000015438 2181400000.0 322990000.0 728230000.0 724770000.0 +GIPC1 10438000.0 0.0 8210700.0 10131000.0 +MGC152010 2791900000.0 3014300000.0 4702300000.0 4636000000.0 +CSNK2A1 166170000.0 188340000.0 260910000.0 171480000.0 +KCTD12 663870000.0 752580000.0 983320000.0 920060000.0 +MTCH1 0.0 21524000.0 16194000.0 39023000.0 +ENSBTAG00000001700 3788300000.0 3963800000.0 3955000000.0 3972100000.0 +MSRA 13810290000.0 14631050000.0 22953210000.0 24060900000.0 +PPIP5K1 18596000.0 0.0 0.0 0.0 +ALDH1L2 326580000.0 97406000.0 139840000.0 172960000.0 +DHDH 8638800.0 9531300.0 16282000.0 20249000.0 +CPS1 65033000000.0 60378000000.0 33664000000.0 31457000000.0 +TJP3 1250900.0 0.0 0.0 0.0 +PLS1 15541000.0 0.0 16709000.0 18218000.0 +PABPC1 607930000.0 656990000.0 391730000.0 458100000.0 +MACF1 7325000.0 0.0 0.0 0.0 +PABPC4 75009000.0 83386000.0 50404000.0 61454000.0 +H6PD 881570000.0 161700000.0 722450000.0 749530000.0 +CHCHD10 93071000.0 118410000.0 147040000.0 160680000.0 +GRHPR 3469300000.0 2818600000.0 2613800000.0 2520900000.0 +JSP.1 54883000.0 103500000.0 59392000.0 94205000.0 +DLAT 102800000.0 16857000.0 146050000.0 156370000.0 +DNM2 83085000.0 61660000.0 100170000.0 136160000.0 +DLGAP5 280400000.0 281980000.0 419250000.0 496820000.0 +ADPRH 167440000.0 134090000.0 152510000.0 184390000.0 +PDHX 108620000.0 100420000.0 131090000.0 134150000.0 +C14H8orf33 20855000.0 24378000.0 17832000.0 23426000.0 +TRAP1 260620000.0 288860000.0 138440000.0 147340000.0 +TRABD 33844000.0 24659000.0 0.0 17726000.0 +GOLPH3 73283000.0 68236000.0 57990000.0 61765000.0 +TUBA1D 9018100000.0 8996400000.0 6776800000.0 7086400000.0 +ARHGEF37 3007700.0 0.0 4016700.0 3471500.0 +PIK3R4 4249900.0 0.0 0.0 0.0 +PIK3R1 3783300.0 0.0 4150500.0 4660700.0 +PDHB 1559300000.0 1350700000.0 675680000.0 614470000.0 +OS9 34952000.0 16090000.0 48385000.0 65828000.0 +GYS1 3476400.0 0.0 3587900.0 3989600.0 +DSTN 128120000.0 123830000.0 36265000.0 33960000.0 +GYS2 211320000.0 155400000.0 78435000.0 82918000.0 +PCBD1 0.0 4009200.0 157040000.0 126560000.0 +ENSBTAG00000047868 88564000.0 110880000.0 107790000.0 96271000.0 +ASMTL 16602000.0 40011000.0 50649000.0 47064000.0 +AP1G1 36476000.0 6237800.0 22516000.0 34443000.0 +G6PD 55189000.0 55741000.0 68413000.0 95358000.0 +HMOX1 2070900000.0 2136900000.0 1795300000.0 1898100000.0 +USP10 36746000.0 43844000.0 45100000.0 34493000.0 +HMOX2 615617000.0 726136000.0 527020000.0 638961000.0 +ELMO3 1760100.0 0.0 0.0 0.0 +AASDHPPT 97840000.0 105810000.0 89461000.0 99286000.0 +GATD1 62515000.0 61136000.0 63743000.0 108430000.0 +SULT1B1 1874000000.0 1822800000.0 1691200000.0 1823900000.0 +TUBA8 34374000.0 37694000.0 30326000.0 27279000.0 +RAD23B 23657000.0 72828000.0 28078000.0 39228000.0 +EHD2 11750000.0 8164800.0 7500300.0 7027100.0 +EHD1 62531000.0 89941000.0 63258000.0 73367000.0 +ZER1 931480.0 0.0 2859700.0 2585300.0 +RPS18 112970000.0 107120000.0 82309000.0 85997000.0 +IYD 148360000.0 174420000.0 125030000.0 108810000.0 +STOM 2047600000.0 2194800000.0 3056200000.0 2989300000.0 +RBKS 121110000.0 146550000.0 178560000.0 198220000.0 +NPLOC4 23630000.0 34367000.0 27489000.0 22626000.0 +IDE 6399000.0 0.0 14748000.0 13397000.0 +MBLAC2 88137000.0 86568000.0 81174000.0 68798000.0 +ENSBTAG00000038171 3519700.0 0.0 0.0 0.0 +FAHD2A 5571100000.0 5918600000.0 5208700000.0 4970800000.0 +TMED4 666600000.0 777420000.0 543140000.0 535360000.0 +SNX5 483730000.0 360640000.0 400850000.0 392090000.0 +TMED1 45074000.0 41812000.0 52257000.0 57954000.0 +CGN 133130000.0 5419300.0 44349000.0 45761000.0 +HNRNPR 220300000.0 232720000.0 219180000.0 268950000.0 +ENSBTAG00000035584 4798300.0 0.0 8169600.0 10749000.0 +TMED9 2893300000.0 3302600000.0 2770400000.0 2433800000.0 +AP2M1 174340000.0 208170000.0 246860000.0 254070000.0 +HNRNPK 2413900000.0 2438900000.0 1992700000.0 1777600000.0 +HNRNPL 463100000.0 534120000.0 464780000.0 478980000.0 +HNRNPM 291523900.0 312651000.0 334282000.0 364367000.0 +PML 56936000.0 27323000.0 38091000.0 34213000.0 +HNRNPC 776760000.0 834790000.0 1055900000.0 1076600000.0 +HNRNPD 1250100000.0 1148800000.0 1062700000.0 1007800000.0 +RPL27A 82969000.0 219440000.0 113470000.0 169980000.0 +HNRNPF 277060000.0 253410000.0 378080000.0 291820000.0 +TMEM205 68459000.0 195260000.0 191020000.0 126030000.0 +FMO1 5945400000.0 6490600000.0 9987500000.0 10148000000.0 +ENSBTAG00000038549 232750000.0 249300000.0 373940000.0 424670000.0 +RCC2 27806000.0 28080000.0 16173000.0 18826000.0 +PBLD 3249700000.0 3513100000.0 4686300000.0 4380100000.0 +EEF1B2 562230000.0 481700000.0 667050000.0 653720000.0 +ERP44 1348000000.0 1498600000.0 1297900000.0 1316400000.0 +GCAT 5382400000.0 4961300000.0 5530800000.0 6278300000.0 +STAU1 29957000.0 37825000.0 31143000.0 28898000.0 +FAAH 17439000.0 9643300.0 23832000.0 14821000.0 +VPS26C 113060000.0 116510000.0 122570000.0 133220000.0 +PSPH 407370000.0 442680000.0 374170000.0 435570000.0 +UGT1A1 1518800000.0 1368130000.0 1768610000.0 1982390000.0 +ENSBTAG00000002943 108960000.0 116710000.0 66086000.0 62555000.0 +PGPEP1 318030000.0 246580000.0 315110000.0 345340000.0 +GLUD1 29655000000.0 29556000000.0 31977000000.0 29422000000.0 +ENSBTAG00000037613 79423000.0 55485000.0 131260000.0 149400000.0 +TIMM29 105770000.0 93994000.0 102570000.0 136000000.0 +HSP90AA1 5334700000.0 1532400000.0 1907700000.0 2031200000.0 +TIMM23 112960000.0 93899000.0 151110000.0 108220000.0 +TIMM22 0.0 0.0 0.0 0.0 +TIMM21 64127000.0 57016000.0 38849000.0 31862000.0 +KARS 115320000.0 99866000.0 98437000.0 106740000.0 +HP1BP3 18219000.0 13844000.0 33875000.0 30816000.0 +NDUFS8 534330000.0 610750000.0 610280000.0 639950000.0 +CYP2D14 4334900000.0 3897300000.0 5847700000.0 7050300000.0 +TXNDC11 2247200.0 0.0 0.0 0.0 +CD58 23693000.0 25817000.0 72580000.0 44734000.0 +SCP2 5739600000.0 5868200000.0 6372300000.0 6054700000.0 +MSN 142050000.0 31677000.0 88961000.0 92443000.0 +ZNF326 5418500.0 0.0 20543000.0 21723000.0 +CACYBP 1195400000.0 1393100000.0 1200600000.0 913130000.0 +PDE2A 2195700.0 0.0 1515100.0 0.0 +OPLAH 65110000.0 8258800.0 59809000.0 82824000.0 +SEC31A 352840000.0 253140000.0 496690000.0 422670000.0 +PRRC1 173280000.0 144380000.0 105560000.0 97495000.0 +RAB35 184150000.0 210390000.0 210900000.0 146690000.0 +SRP54 16870000.0 0.0 17183000.0 0.0 +RAB32 199490000.0 188260000.0 351400000.0 358680000.0 +CAND1 143430000.0 0.0 113590000.0 111100000.0 +PRPS1 653600000.0 756410000.0 811960000.0 707820000.0 +DAO 333390000.0 272980000.0 483960000.0 495640000.0 +TATDN1 100810000.0 103650000.0 152670000.0 202680000.0 +ENSBTAG00000037509 3239100000.0 3031800000.0 5003900000.0 4721000000.0 +RPIA 529880000.0 493570000.0 486610000.0 396180000.0 +TTLL12 137580000.0 31001000.0 102560000.0 151130000.0 +LDHD 30163000.0 23224000.0 57165000.0 30997000.0 +GMPR2 1031600000.0 1196000000.0 1168800000.0 1186300000.0 +LDHA 14870000000.0 13195000000.0 7208500000.0 6815000000.0 +LDHB 90843000000.0 88904000000.0 60403000000.0 58145000000.0 +LDHC 536100000.0 426860000.0 448290000.0 374210000.0 +LONP2 43884000.0 15621000.0 38450000.0 34587000.0 +PLS3 741000000.0 726080000.0 702790000.0 743600000.0 +LONP1 553770000.0 100790000.0 301640000.0 541030000.0 +PRPS1L1 14452000.0 143990000.0 204130000.0 173310000.0 +PDIA6 5536300000.0 5153100000.0 5742700000.0 5418200000.0 +PDIA5 287100000.0 277620000.0 269670000.0 311580000.0 +PDIA4 3752300000.0 1290600000.0 1720300000.0 1680700000.0 +PDIA3 11361000000.0 11404000000.0 10557000000.0 10780000000.0 +GAPDHS 0.0 27573000.0 0.0 10917000.0 +CFL2 273520000.0 244060000.0 155080000.0 116930000.0 +CFL1 2096000000.0 1982600000.0 1271000000.0 1574900000.0 +PLAA 21632000.0 30059000.0 23076000.0 24565000.0 +BICD2 588990.0 0.0 0.0 0.0 +SEC22B 702980000.0 952600000.0 1044700000.0 1106500000.0 +NFIA 72864000.0 84889000.0 132520000.0 107650000.0 +CD163 11492000.0 0.0 11306000.0 5193400.0 +AARS 146460000.0 9450400.0 61691000.0 59180000.0 +PDCD6IP 385510000.0 34680000.0 144850000.0 133720000.0 +TSGA10 10537000.0 12086000.0 8208100.0 0.0 +DNM1L 11295000.0 18871000.0 21188000.0 19447000.0 +SERPINH1 65738000.0 86493000.0 87575000.0 75870000.0 +FOLR3 71727000.0 76916000.0 40142000.0 41058000.0 +C5orf51 101150000.0 94942000.0 112990000.0 90720000.0 +GSTK1 3823200000.0 3929400000.0 4085200000.0 4575800000.0
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/transcript_data.tabular Fri Sep 14 12:22:13 2018 -0400 @@ -0,0 +1,2818 @@ +Gene D03_01 D03_02 M14_01 M14_02 +ELANE -0.08223053805901 0.128367421476871 0.168575604288361 0.179386061121957 +AGL 18.3503026568495 18.3971714903452 28.8550772364392 28.2897976837947 +AGK 4.96373192231441 4.0307358661387 4.69732878268058 5.64327232883133 +HSPA6 0.350288503153011 0.592013587104232 0.612568173305459 0.833794197245084 +HSPA5 413.409614153405 438.011930274678 197.673685843884 193.727515486021 +HSPA4 14.8468997976502 15.3061633055397 15.275973226593 14.7835817685183 +HSPA9 170.253077768686 169.323500684362 159.978594056721 161.35877481037 +HSPA8 486.867209766023 498.041303389437 352.185123018411 340.356699934716 +AGA 55.2930712045865 50.7686596245107 69.9129100715734 66.07384169934 +LGALS3 12.3566659422422 12.6797640900226 18.7284481408449 16.497115341329 +CSNK2A2 20.6258110499688 20.054472820524 18.5817134405737 18.3292680140834 +PMM2 21.8385112586243 23.0035148281517 16.003600132562 17.2109074501839 +PMM1 8.10344421010251 6.45300943797042 5.29673056867481 5.29511229568809 +ASS1 1516.70059430521 1464.12181445199 987.76849371654 994.644000920779 +SPR 29.8024212677962 31.4255886777817 31.79677566883 28.6670221909796 +RNF114 33.1294000243847 33.6664789344251 28.9252501819995 29.2816301523686 +UCHL3 24.423075481539 27.4024225580356 29.922955743965 26.0349789575326 +ENSBTAG00000047256 0.198684163979848 0.326976011762912 0.0965464670861903 0.195629128584535 +ABCD3 58.7883234930997 65.4050144271272 44.0781156389721 45.9473853318538 +SCLY 18.3455097325074 12.0439548297371 14.5431284057665 13.4342441387722 +DHX9 32.2266699445344 36.0820538117998 35.4491208799006 35.8446454974175 +OSGEP 29.0980770472159 32.8130489058944 28.7841249063531 29.9202928144102 +NUP98 21.4830493303323 21.235967445222 20.6724652583012 22.2449776146426 +PPP2R2B 31.8301859398506 30.1268425510797 23.5899320354255 24.1446221529343 +GOLIM4 77.5784923330104 79.4625370538813 112.276390607867 104.067050552795 +ENSBTAG00000039928 359.614982869772 382.125322623553 543.941055328692 546.030125904376 +OPA3 5.18347064997793 4.15589059496056 4.03566324685585 3.86302350820354 +OPA1 17.0182215598298 16.1769424590617 14.3846256512375 14.6461260137112 +PIK3C3 9.84397565598685 8.70006988836737 13.5221256093077 10.8636519932476 +GK 65.3713999987646 68.7043984462497 24.7873549302085 25.9121453607769 +PTRH2 17.909813910486 11.7471606497093 10.9263216383985 12.0202004570597 +HNRNPDL 37.5925704923559 41.1578984184042 54.6425179347757 52.9859134623444 +ENSBTAG00000024233 37.7416967628295 39.5317543165011 38.5879336019462 39.9028585669302 +TRAPPC3 17.0068732811101 16.3667538068817 15.7092710313949 15.4243816805198 +TRAPPC5 45.0403443110014 42.0513255117671 28.9286451423378 32.7199255117285 +ACLY 13.4740474442297 14.3387262055932 9.58029287059529 10.3337981947598 +CTBP2 5.99360085192578 4.51762221965351 4.98093076698102 6.42950200799512 +ITGA9 17.6306543365399 17.8886530469848 22.7476079210683 19.8507879088077 +ENSBTAG00000021558 21.1194017135072 17.7807242658146 20.1526593853834 18.2217376654255 +HACL1 246.657620535078 256.567529495172 229.415834596451 220.138080113882 +ITGA1 9.29786949411024 9.76396771663312 13.5013428589913 14.8294210742118 +NOP2 6.80838573089712 6.89524552209448 6.72211107944166 6.36046866759143 +ITGA6 11.8735075257508 12.6555131238251 15.482031234154 15.5906619691222 +PDCD10 18.7315219469136 22.601547803977 21.2323631686951 23.5166048769705 +ENSBTAG00000014423 145.95935840011 143.533614530968 183.076474422877 181.551319884355 +EDC4 5.52923753091842 5.7877027035443 5.23171974237195 5.96904629810924 +APOA4 1001.67305558535 942.744279140933 107.00083069641 106.440618749974 +APOA5 1029.86419861909 979.325280504821 674.842850735208 668.048257430335 +UFSP2 16.2749903128682 20.256738769108 18.7220238728349 15.9515918998196 +XPO1 16.485245004257 16.8668226905226 18.4411687253671 18.2090074546333 +CSDE1 88.2990636083208 94.874140787585 111.6583797805 112.40205326067 +XPO7 15.7401949501504 14.2091535237298 17.7515728413077 18.037145679691 +MRPL28 52.9893031681559 48.9584949101096 42.2163527456254 40.7325874477505 +TIPRL 20.3593806662543 18.8266323736025 22.1406027919464 23.9116420800724 +LSS 69.4405230982464 67.9177325717943 34.6165192487874 36.4756780332274 +PSMG2 24.3340985914468 23.1473288109428 20.1222558498083 19.2832537875864 +GHDC 18.4919529769017 17.5838035280669 18.9382753160037 18.0121064664024 +COL4A2 15.5642265337804 12.9203859487482 12.6604151875499 11.5741214026047 +COL4A1 18.7737518722348 17.9754153048966 14.7656650528014 14.1620652210673 +MOGAT1 29.214304014299 27.2106358144939 48.813385462078 45.6665374274383 +RBM12B 10.2220215777789 9.08546549239542 9.59408615710437 9.39417720968644 +GART 21.5436980575652 23.2984700656073 24.1828609787347 24.0004515765337 +GARS 10.4910364163667 9.58944697505935 9.87971225491647 9.63543758311674 +PSMD14 36.0575786878339 36.4148897543947 27.7902740804373 27.2684578677359 +ATAD1 25.413418725973 24.7301016946236 26.4360294340748 26.6545479857708 +PSMD10 13.5768391812326 9.3532359211042 10.8405613619929 12.2488783349383 +PSMD13 43.6839875293078 48.0199832997457 51.2565442656727 54.7745310242926 +PSMD12 32.3869688289328 35.9623944517067 34.9204575429278 32.647504142095 +ENSBTAG00000039321 112.259112376834 100.238484530008 58.6067447808408 59.3027474433137 +FTCD 309.573136539452 295.074871337398 274.566642289599 275.934257978524 +GIT1 5.98665615660445 4.13219088841018 4.31070407993306 4.07519319098542 +SERBP1 92.6844087711888 103.442915624876 117.427762984193 118.124478506835 +PPP4C 55.7197885548943 55.2493692622856 43.4455864375624 45.176077879304 +OCRL 10.3264092206792 10.9789449669842 11.959814900627 10.4136711254052 +GANAB 64.3122238655378 65.0695408590483 71.3203377582816 74.2726862141167 +NUP133 4.45902286123096 4.84535662254183 6.72438653093649 6.17882466580224 +LRPAP1 39.6607118298376 39.667324289904 29.5432412799297 27.3187118073329 +VAPB 33.8702904392001 30.2693811622097 31.4173326842444 29.2929310980619 +VAPA 76.1546605041493 81.3371215996031 81.6706014323395 82.1110532113614 +SHROOM1 21.4810018134023 18.4561566411643 21.5571482143965 20.697368126951 +NDUFAF6 27.2882339620369 25.4094168879516 28.2550995885815 29.2385834162002 +MTIF3 33.0636275228121 29.8367202861899 27.5634090338781 27.5477833560371 +MIOS 4.26591122111643 5.21359359064982 7.12579399384903 6.83589766649823 +SNTB2 3.44676097069901 3.3371843145823 2.52823542190094 3.34353582107334 +IGF2R 20.3869302286559 18.4169743231909 21.5848513751896 21.119359211056 +CTH 23.7452527235334 28.0730838392641 20.5257484503605 17.8868290710971 +ARL6IP1 366.492111230662 413.904559500269 341.945846819416 344.091482581901 +SPART 22.0039686136008 22.2710603819198 24.2563861964032 24.3687278917066 +ABHD14B 139.93182580896 142.076678793288 138.017203335669 141.447561047386 +NECAP2 32.342511082654 29.1683949165178 30.9004923222674 31.8135482422216 +ARF4 177.906467824909 185.11386912031 120.919332619611 117.322225614047 +FAHD1 23.4790229313779 26.3252143975123 23.2631431801679 22.2514583136608 +ENSBTAG00000009622 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +AP3D1 35.3786363820956 34.5749292219143 29.8908508467828 31.2156269399088 +EIF4B 154.524576676941 153.28152421075 176.12154082364 184.124226128935 +ZSWIM2 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +ENOPH1 15.4055430899225 13.8419843115498 21.5808205115286 20.7971877299735 +SULT1A1 845.575240323372 814.50990400149 782.934194000434 785.782825518319 +TCEA1 53.5643588897778 55.7535934144872 43.8579071646478 50.0118717755338 +COX4I1 309.919683480587 291.014671463711 253.02526267569 246.837605760305 +PRKAR1A 75.0317104266905 75.6797180159207 67.6452882356599 68.086861744805 +MOB2 8.34698503488294 7.88178344525066 6.28178957023459 7.79647994110156 +SAR1A 56.7295062911519 51.4765112093329 59.5206613514234 58.4317153725386 +SAR1B 70.3457473197658 74.2411191917892 93.6695949365961 85.9996902150374 +NIPSNAP2 22.2409279443414 23.6675529379508 23.7958240572163 22.2304188233296 +NIPSNAP1 261.760193663487 257.808857903779 282.981075524417 283.129564822466 +PIPOX 59.2527204027095 55.7123593473811 72.0030323551228 71.040024233988 +GAA 22.8247118216386 22.3220096464427 15.5252186804416 14.2809388207976 +FGL1 2555.98920665391 2628.44831974902 3284.2932551994 3274.6102441295 +METTL27 18.1913067140135 16.5254690880281 11.3830492437096 12.7694618928597 +METTL26 35.165014623508 30.6060665296889 47.0401804068985 40.6256404639011 +SPP2 1784.99498394807 1798.12910993085 2319.1080452268 2301.08216805348 +DDAH1 38.9178538545167 41.0705326162855 44.3938943848196 44.8720457230236 +SPHK2 19.9238628097942 19.8335687969203 10.0651876263558 10.735626778193 +IFIH1 7.03896789737137 7.08042454247708 9.70047174052227 9.63188806787781 +DPT 14.684224587926 15.1690900417726 1.65584269235146 1.53089191181918 +IPO11 9.78747564766886 8.42943393013128 10.7166326702021 10.3850789048885 +EEF1A1 3529.66359717918 3775.55204622843 4257.79444312061 4202.71665392599 +HMGB1 127.814223095732 126.102728522203 134.537795502212 126.782452387701 +NADSYN1 34.8115709446594 30.9374810391975 30.0315749194893 28.6156343632691 +FYCO1 11.8833517675312 10.3416387364826 18.146604971577 15.4921469995441 +RAB2A 62.5509676241328 66.9966912236371 56.0323977714773 53.3226922315867 +RAB2B 5.51549912033921 6.47597494872138 8.00535272209009 7.39671182238791 +SRBD1 8.31459314631765 5.40203128694332 10.8599607699136 8.8923374959611 +ABAT 93.6090018664263 94.0604435927781 85.0992264753205 85.9840040189955 +ARHGEF2 16.1006521844568 15.7284670256871 12.4995761183079 12.7035062890944 +NFX1 20.6905826175321 21.5102719233328 20.3686983067127 21.4631053285698 +WDR45B 11.6549980415905 11.1523722350841 10.0822519746743 9.82223941788683 +DPYD 125.826066238406 130.930045213624 107.686919723906 108.256599018326 +AASS 7.8914461669373 8.13970359677149 6.73944044936138 6.3483393338133 +RDH5 1.79251889795048 2.72783739942013 2.69293715060828 2.81803975238425 +PEX14 42.3812981701585 43.4688919742291 31.9647855676644 29.6196348337707 +DPYS 415.526138098317 428.867293349806 495.757493643467 493.853439305384 +CLIP1 12.9868704613915 13.4886510950039 17.5827108973963 18.3290029094934 +ERAP2 17.4247579503051 16.6562757190611 20.5361587574596 21.8824164306055 +TIMM50 29.3492678861377 27.4006185258684 26.1342457867284 23.4351295484163 +ENSBTAG00000047529 149.495513086567 139.342071872203 24.1801671225914 22.7082887605049 +DHRS7B 18.1950043251175 18.4823562687571 13.6463389222502 15.6253624250419 +CD46 65.3726198053503 74.270239910639 101.054275282023 97.1873411657754 +DMTN 5.92399265481323 4.4561329283421 6.08392838520068 5.16829312410744 +HIKESHI 96.2207036892234 100.160285992896 68.7098155791241 71.5239930710969 +FPGT 14.3094893013407 14.6812299826117 17.8287642243643 17.8191309005061 +RAB21 27.7472527702365 24.9532945239171 34.0969791040787 29.8855752260238 +CFH 767.294507242946 818.173178670704 1041.15753075284 1048.53215116834 +PNP 332.470624222216 335.399776703518 341.594319111974 337.879549287364 +CALR 547.808827828665 544.550148715678 311.993698451087 314.830818784292 +CYB5A 1279.71947937063 1386.20747777369 1278.94847592941 1279.56595705498 +CYB5B 118.775991716626 123.256467544453 65.7720989249889 73.6310240206118 +NGP -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +PIK3CB 3.8517453800314 4.46490589534062 4.02996405177878 4.5529561992062 +HNRNPUL2 47.4234424954677 47.1056769107593 44.4535735677995 42.2584653992133 +ACTR1A 21.7299478723611 21.7936385705149 16.1674085490479 15.4133085835672 +PNN 36.4129816672753 36.2587500070935 32.7810351218855 34.661968292265 +CHID1 66.5172347638444 64.0181074125876 57.9733031916989 55.3420779019853 +EWSR1 54.1683946610428 53.0021535902792 53.9936184091863 59.0360940996303 +PCK2 251.203985954915 243.616925385796 140.766920970437 142.830793766762 +RPN1 116.718849259482 108.288455429388 75.0381777229905 78.0666545276412 +TRIM13 10.3084486149378 12.5857697617364 13.6427168919822 13.6854569313284 +PCK1 1265.75686610038 1236.34525852274 1406.69713146692 1419.48730399179 +NTAN1 62.8797536647571 69.1947937594922 100.707922686855 108.831439179798 +NQO2 222.62209856547 190.96696710527 137.944437885814 131.294377867393 +NQO1 32.7668453881373 37.6680611198006 30.5202232334309 32.367387170966 +PRPF8 45.536241120716 44.7936380566713 48.1251730294754 49.1573339523372 +CYP4F2 137.317057716928 138.703061951477 75.4866875958729 73.1834721663011 +PRPF6 16.7526636813592 15.2311379981886 15.7555916952368 15.0976180464327 +SAO 1073.73742208767 1021.88943986436 830.50559434436 833.477853092995 +CD177 1.1064766601143 0.953317941290519 0.341218021933693 0.153610807026454 +ESRP2 50.3155261869543 44.619485168079 47.1721194966727 46.0241969281125 +CNPY4 10.0073895725895 11.7091870323942 9.79011112829774 10.0635723357581 +CNPY3 45.6062009119591 54.6688278769568 42.3361904744904 43.2902187714202 +CNPY2 52.6939452099784 57.3174560133973 64.3741910437105 57.026286264242 +UFD1 37.490492039711 35.9029843625734 38.4924783278795 39.7174601812313 +HDGF 132.114229179939 119.157426899464 93.5406149231975 100.903906100436 +PIP4K2A 9.94077180962714 9.9601190548232 12.273037893579 13.5319122184368 +PIP4K2B 11.3854163174358 10.1401622345344 12.1726641243729 12.8141966973479 +ARG1 398.397801204718 416.700438067688 177.985789305031 181.145073922015 +MRPL39 17.6479220239243 18.7867561846128 26.0920872201995 23.3437776703563 +PPP2R5A 83.2787384234597 78.7383482087907 91.5819522630186 95.6081897061122 +TBL2 17.6044406984494 16.6717367518503 15.8876868352769 16.6080879411354 +THOC6 3.154741233258 5.01941914482926 3.22597627195503 3.49366554248318 +THOC5 17.0476717492872 16.4936245013996 13.6715969398354 14.2331407939343 +FAM45A 10.3567182569904 11.7069399026618 15.1140708030144 13.1451402101531 +CSAD 121.646520077837 127.750510244592 36.8610759318546 33.9018548891293 +MGC127055 224.575619797312 200.27769415398 317.239513685238 327.427273286726 +HSD3B7 97.2473056730277 87.8609258855866 141.355082856094 132.414109745301 +UQCRFS1 141.454214766287 131.924019658601 110.639769549328 104.86438684157 +ABCE1 15.8248475055053 21.8172616033683 23.4067588945618 21.8118736662113 +UQCRC2 152.230541812823 166.808493235143 126.328662289673 122.994402255727 +XPNPEP1 41.8807649441074 40.6081698661029 18.3535845813194 18.7479346711993 +XPNPEP2 5.30103159227074 5.77207117987478 19.7709539960855 19.8714798966939 +UQCRC1 134.568480174264 126.131237251667 101.775599208664 105.169742148037 +NUP88 16.5887334626008 14.9994854494616 16.8870822233886 17.9216378091807 +COPS8 25.6815415038193 32.1308773946308 32.3689295868065 33.0426964241527 +DDX42 11.9558286042061 13.3755349689871 16.0180555442053 15.028408310974 +RETSAT 111.198575750054 108.234565332469 64.7740124709037 66.3199179023973 +NSDHL 196.206497037071 194.996329006316 95.4511145003505 97.6093615840869 +COPS2 21.8874445010306 21.1471225994447 29.8896354760515 24.9366705753889 +COPS3 36.792558084955 36.012224070399 31.1814705079747 29.7691487172069 +PGAM1 128.197182074873 132.744999071466 115.951538425384 114.043264474737 +KHDRBS1 24.8612093702586 22.7117760447553 27.1193193660084 28.2779244387664 +NUBPL 7.26094544277042 6.27516525710021 11.0926766737667 9.12658370376235 +COPS5 46.7385780403867 44.573471003325 51.450706832298 54.5550979617182 +PPOX 24.4384475237034 22.4650265394009 19.5511294975975 23.1051027157849 +ENSBTAG00000034189 1535.26272411505 1549.7627784892 2220.81535301455 2192.62982443271 +ENSBTAG00000014988 -0.0852424485972669 0.392672184418438 0.229878939571751 0.0160375845066772 +DDX46 13.8211747463843 14.5697069189569 18.310272049786 19.4926863517895 +TKT 90.1527255282997 90.3228079129476 51.1029230044274 58.7600337132427 +TNS3 19.7983720525298 19.2669361780051 26.6583681920854 26.5576747555308 +TNS2 46.3766710579474 40.7834279771236 54.7358598374475 53.3126451539783 +SDF2L1 48.1891283121328 42.0367507494488 21.0318787819253 23.7945977876345 +FDFT1 230.460887232816 245.947318190569 120.763143974621 117.130536954793 +NLN 7.07532998105508 8.54557900985034 13.2274088682484 13.4171960452136 +NUDT8 37.5210877453456 36.0080104212579 41.1581288265437 36.2502195018032 +NUDT9 35.8336134386665 33.3809334485037 49.4797898626705 47.8603339788615 +TARS2 20.2575343976251 17.3790267157561 20.2433971353388 21.5236047391908 +DPYSL2 10.1053007008949 8.85930993697005 11.1086266678461 11.565168833617 +HEXA 38.877016564319 37.7314453646721 52.6980753830058 52.0258756258857 +DLD 45.4312031551119 49.910499454934 54.0517288521742 52.6710590402174 +NUDT1 18.8793782493198 18.8527260787607 12.3038809833938 13.2866843020744 +NAXE 59.3073261395044 55.1293928443162 61.2054448772134 60.3812186171541 +NAXD 57.8955362638437 43.6320101574989 46.991284295244 47.7596406263779 +NUDT5 16.1507454793259 14.6942379912549 20.0543101479719 19.8748659218738 +TK2 33.9979320424689 33.0844481516052 26.6390511054135 32.643749648284 +IGFBP7 96.1715883245993 96.9849127734383 73.8446854539096 80.1413700430556 +EPS8L2 63.1318290081556 61.3573800230007 51.7789907957507 51.8770051707783 +LARS 11.2227190970869 11.5871577365339 12.621647507795 13.8301461988261 +PROZ 116.809886640552 104.858776046389 117.957069400365 117.529049770823 +CYP8B1 412.065295525826 424.999207684934 464.440371255463 456.332400512045 +ATP5F1A 465.782327739059 489.329449302093 369.486001185207 367.713507433185 +ATP5F1B 513.546065335708 528.33262563355 387.362696330798 388.315109609166 +ATP5F1C 165.22570160091 163.302687551094 132.846351531124 127.31907389261 +CYP27A1 330.369783913126 310.29234287436 349.399104678752 343.446147391654 +BTD 33.3813845062862 32.2538602523885 29.7869780486328 27.5510469622459 +NUBP1 11.4048602470467 12.7382574393044 11.1785894349288 9.95118941684435 +SERPINA3-8 168.417714809174 167.970507408395 156.311118422826 158.396478705801 +DDRGK1 73.1256519539238 69.6134279072901 89.4499144554201 87.6467582491982 +GAS2 24.1141839058607 21.6921538411643 25.4995596647139 28.9163000443201 +PROC 257.135492596388 250.759657656163 324.180045008162 321.635705884631 +SSB 29.7339194164135 31.537381503401 32.3697689830767 34.1734894040076 +EPHX1 1282.64070174471 1231.31335477416 1096.1264487374 1106.882416371 +EPHX2 267.254769439827 282.304537311901 291.384664316726 285.555257100128 +AMPD2 24.8937745496354 27.0386591397879 17.7872665597086 23.1796002540168 +EIF2B4 26.4887557965806 25.9363758016864 20.2133086701299 21.7163785368209 +RPLP0 829.702612336098 775.436256693867 651.772908433284 654.881810999245 +EIF2B2 10.8182510719445 11.8213317939747 10.8812350114344 10.4730454873175 +EIF2B3 10.3371570078383 8.67245257243822 10.0647106581741 10.039083091741 +UGT2A1 90.3836856244171 96.8452690777283 116.226869137167 110.28527355416 +EIF2B1 13.1418240517451 14.3039936928032 16.5197542513587 15.0508416887651 +PRKAR2A 27.3648052251888 33.660829367772 28.2743970133358 33.3601940269362 +ENSBTAG00000030882 887.671080444981 876.251886680296 1050.08995355016 1034.351777053 +PPA1 68.8539061719247 72.9347408623078 58.5251629497892 59.3975783114507 +QPRT 223.497888592996 214.633721536292 164.112700149496 168.873988656332 +MLF2 280.835430305601 275.532928515868 234.282285768835 236.378832310805 +ALCAM 24.8530471583304 24.6458417152982 43.2278910081907 42.4831972700685 +TPM4 59.7755367612895 59.504108592511 37.4316111803736 39.2393780376755 +TPM3 80.2482524202322 83.3926516833143 96.460478502711 94.7942037798843 +SNRPA1 21.8486546659052 18.7731575446815 22.3599041797701 19.9420938776355 +TRADD 7.91439177282105 8.05320345058496 6.32019055753322 6.95827046996287 +ETF1 28.0226903934314 28.5075331727821 28.5133031292269 29.5491157617827 +THYN1 125.76550872745 114.034631077185 102.274550689111 104.261178066886 +PRELP 2.26786018926251 1.96606581443142 1.68936641506156 1.76613680814355 +TAGLN 32.099452031918 29.1484424074593 17.5917391803785 16.509390173962 +ETFA 135.141449569574 144.963441695701 130.672574708148 128.225900224345 +PHACTR4 12.5339579904123 14.7522133671977 14.3461622879086 15.0294524007617 +CLIC4 61.8332679529114 64.5166939843832 75.2674611554502 74.2803060751161 +ETFB 209.264228536475 184.991100348228 147.803507966251 144.773413999346 +CLIC2 5.6385595704383 6.55771019944208 7.04816461542892 5.77086834430778 +CLIC1 43.1533587140058 39.9599256941446 36.5331332537157 33.6665460706112 +UGDH 253.02867864416 267.054638155161 212.601167110265 208.290026972686 +SEPHS2 113.476159128145 98.4335183950974 112.942581584812 105.587424112673 +SEPHS1 20.1668788705997 20.0841930429626 12.9833468848857 13.05437399181 +TPMT 37.3539008448681 45.7663089123757 42.2498608667885 44.6219886398567 +ASGR1 574.26165428167 551.397362864625 661.028892970386 668.74644494183 +ASGR2 1498.2023349371 1458.93747322725 653.20127456486 671.437605289062 +TMEM141 6.77638454057323 6.36358018083691 5.34501016871541 5.34043028569703 +DDX19A 10.2264421918185 11.6017514367502 10.9392637149186 12.2002611418184 +RPS4X 370.606210921147 387.615158508429 325.94457278781 295.398196414374 +ENSBTAG00000001219 27.5002915548413 24.1254709605611 29.9956228010897 27.7050791539923 +CASP3 13.6407386113878 12.1131758151392 15.3737406004101 14.7632148560478 +TJP2 23.5471811946994 22.9414444173909 22.2199156676969 22.4503687582357 +API5 24.5120470652308 23.7286927168825 32.7844671733315 34.1936237246548 +TJP1 12.6864601144569 11.5936059129246 12.6392826035758 11.8325757102949 +DLST 52.934832417484 51.1588093239547 46.7562965795153 48.2045508515671 +TCP1 112.131202207662 110.910440071749 97.4706808780156 90.2564541447596 +PPAT 12.9663599130648 13.4127577044066 16.5679134408528 15.7026652137807 +XAB2 10.850398910469 7.45428243618544 8.60682146979172 8.74181328016818 +KTN1 13.5917939719345 13.2862990084361 14.2256517291323 13.303763734422 +ST6GAL1 165.229264975642 179.239983837993 124.694954568808 127.499990199542 +PRDX6 134.230883044861 133.103972206919 177.160396297109 173.982741992254 +PRDX5 141.574940423992 137.725992770752 131.031605344666 137.814420150429 +PRDX4 87.8696821185557 95.0781960700951 64.7507646532726 73.9173233612039 +PRDX3 226.183756366869 236.922452938662 211.134649736436 212.569740450738 +PRDX2 26.5557760752879 28.1974369071007 17.0004894733476 16.2288890611705 +PRDX1 74.3912473879908 70.3300111920131 72.9684635138833 77.3066978965897 +CLGN -0.0769494798646383 0.134583609833271 -0.00515264632226811 0.0623934897114842 +SMARCA2 20.3593132759385 18.7902611833367 30.6744398451897 29.688136681472 +OTUB1 25.8982325862306 30.0692658747372 34.5873136404171 32.7595878205512 +RABL3 16.9469843721439 19.6807527614847 17.8762456131016 17.4418933997269 +PLPBP 23.8636810065543 22.0581080082221 20.8171521244186 19.6413481588875 +PDK1 13.3819325431579 16.2490439405129 20.5817877798094 17.1517929071161 +CD93 15.9086560245681 14.7094557809897 13.0258049347392 12.7060245724838 +CAMP -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +POR 135.154827598721 108.541471373971 133.848368946207 137.090730361401 +ENSBTAG00000009760 6.46415271214865 8.26146386647607 17.1078553775569 17.9350562212556 +MPRIP 18.861432035832 15.5098865277044 15.3997932307497 14.833519534604 +TOR1A 33.4847560379608 33.0946703435662 26.5562010236844 29.1095049016675 +HNRNPA3 102.155542447621 105.978780204414 108.356531149615 104.728720082175 +KANK2 13.4497827047211 10.8610886777587 9.67268601983471 9.31600165426222 +SULT2A1 544.420560738779 587.138429835008 600.605989642546 619.620066264069 +RAB1B 64.8001697709825 61.6704468875612 74.4870293049082 73.5811598080436 +RAC2 15.1528799674561 16.6120161683308 21.5805335239663 22.9098008728685 +RAC1 144.871933193455 133.76419069935 110.544995623283 117.714557016536 +SBDS 52.3300951995314 58.8510105177794 71.2287538949878 68.4988115280331 +KANK1 38.7083668936645 39.0613346432396 59.8783082517713 58.0948282444095 +VCL 12.9864940162902 12.5103186763001 8.93598455816918 8.95075998339195 +OSTC 84.8346216299972 84.4508821875817 91.1304891053569 91.8217268065564 +VCP 140.535918088026 143.476321536453 125.127227850425 128.982120434154 +OLA1 25.1824643374335 25.931751376637 25.0604072981031 22.7585162618521 +AP2A1 22.0182379500007 21.5486712028007 15.2611711684692 13.934489196156 +AP2A2 27.1697890312162 26.4417489134357 21.7610471693701 22.1951339983571 +LYPLAL1 3.34899680322929 4.66833172405662 6.12858842111593 5.23066328320325 +CYP7B1 23.1360768551171 22.4690579382223 62.0391905328311 58.145626153812 +MYH7B 0.16456422572363 0.254542260320269 0.0230733681785335 0.0140036826877487 +DPH5 8.92866530606837 9.44685179381996 10.110233626372 9.48675065538081 +C3H1orf50 37.1672354579663 31.0344286542843 30.3352622287305 35.0610534192782 +BCKDHA 33.3347140933374 30.3699155604248 32.5880478602026 30.0470161238574 +TARS 58.3346523760796 61.3452927342599 60.1174891333598 62.5639925423971 +TIMM44 12.7707734182071 13.2493063107241 10.3639663791509 9.05734653636706 +TUFM 68.8048800326677 66.3901386072852 55.2240841678637 55.9380345267129 +LAMP1 570.166468356905 531.539077614722 550.370817248693 549.20043514358 +LYVE1 42.332090907862 44.7807626316673 59.3734080880618 58.0638912714492 +CKB 15.6671458050596 19.9648955893968 17.7557976420411 17.0109074209085 +PTGS1 7.48905023674876 7.64979664168315 13.8381202850499 13.9880384661815 +ERGIC1 49.6443473408582 55.4931623743165 43.2607031334041 40.8211731904949 +TXNDC9 18.0969611430883 21.8941370380688 23.7607006653692 24.2262949098011 +CLEC14A 10.6122879481349 11.0813991506722 12.3059657369904 9.95524992723328 +PAH 1044.11626930845 1049.80153097312 1359.04203448889 1350.35018648269 +TXNDC5 77.5284698782203 67.8020339385372 55.0017892229316 51.0694326103712 +CPPED1 43.1981228276528 40.9683829313164 49.7615116871596 47.3353298793024 +DCN 59.5307921342537 59.4208950657746 54.7991865479456 54.9461564976765 +GPS1 24.7958745262074 26.0022920374557 25.6580994092983 25.1252546804033 +CALM3 35.0709614614792 32.6332399605844 24.2324170704281 23.7202940680336 +SPG21 46.4223372009773 51.4042757420462 48.533670026875 49.4211358539337 +ACSM1 827.562355463645 844.15943074068 928.901400582796 929.387840748824 +ACSM3 169.150483252366 182.11344091291 262.814704088015 260.952011118048 +ACSM5 20.046581368137 22.4926241797368 34.3780747297027 35.465762332379 +MGC127133 8.86111406835099 8.50752222605345 7.02451247034377 6.02444418176124 +CYP51A1 157.12698521429 165.206017985066 68.7660597227103 70.491810220329 +ATP6V0D2 1.2341975788172 0.877167935857445 0.777383419071078 1.27526958392675 +ATP6V0D1 65.8683638418193 55.3304641920697 45.5815637735467 53.4373602438446 +WDR61 35.1110800682472 37.6202389497737 39.2644006433297 39.259368680735 +ENSBTAG00000022570 19.0019095044803 19.2707444121756 39.4668053612846 37.8408914025013 +CUL1 16.1500566401071 17.438451527384 17.4691912519176 16.5805214948805 +CUL2 8.13870687807213 7.98038561274466 10.6627483654666 9.10580856651355 +PSMG1 28.2621158656397 25.8711204741751 29.1648864546432 31.4253545205057 +TTN -0.0523068519948276 0.166094765457831 0.0224945492390797 0.0391090796486431 +ENSBTAG00000038058 55.9058490183006 54.7538130787994 71.4213192687985 72.0976616658343 +SLC25A3 132.951249188516 134.078827981023 113.992097344352 124.128902179982 +TRIM25 30.7042091635934 35.5036670406055 39.1545231540834 41.2647931983878 +SLC25A1 311.615151485823 291.250873522062 179.304384821911 175.465855438779 +PRMT1 37.9333215497911 37.3828617282321 30.2560508678175 30.4004632500649 +SLC25A6 285.342697198011 252.86427745884 191.315006725148 190.951625186782 +SLC25A5 37.5835112064881 40.7882634457076 24.8334313386296 24.3137005206595 +SLC25A4 198.579965337122 203.687381210991 159.823810749347 153.543858264709 +HMGCR 127.264561169596 127.317153095414 49.6285053841519 50.0187086639129 +LZTFL1 14.9220708084475 13.5434796682992 17.9301984441499 21.2681592038123 +DNAJA2 47.6871913084575 56.6977738539339 69.131122034082 63.159470565716 +DNAJA3 51.3205333889838 49.436641338831 42.2481062572819 44.0364892819402 +DNAJA1 120.318868007511 127.170136462854 118.337994014837 116.922400151691 +RBM47 15.0297379298076 13.162524735772 10.5656005250471 10.6984404424176 +PTPN12 21.8950094956548 25.1566975935055 29.7641231071949 28.9249195900597 +KIF5B 21.3824382590587 20.6115864462121 21.6553260044545 20.7240378178645 +KIF5C -0.0242909356493393 0.169992433972603 0.177050708567648 0.0828988899603681 +MASP1 31.5939174041741 32.4197437525564 52.9779224202884 51.6513474135442 +ARCN1 68.1819355685582 69.1212495370072 54.438343452279 58.3613437871432 +UTRN 10.4992129523934 11.0711887799641 13.2795767305464 13.1166368811989 +GLT1D1 82.129491077376 79.3352312187318 73.8723339790502 76.2114824680646 +TTC19 13.0523861886925 13.1435830833606 13.5480758176078 12.157710960407 +DMGDH 117.708296045597 118.203564915098 122.923367633367 121.162722874162 +ACADS 464.557981988281 431.75966394129 432.015623447996 427.665527364402 +MRPL21 16.958495295684 11.0579595157229 12.7933224431094 11.5197658017626 +MRPL23 734.304345916776 673.026586156728 555.080627196372 541.114736674224 +GBA 30.3706492397304 28.1343923107183 29.4137112184891 28.0771909890332 +DNAJC25 35.0149401389874 29.5731279565976 22.0094234922849 26.876907639099 +HSPG2 5.4379276412408 5.00249535538277 3.3669523301715 3.73500814553961 +GAPDH 1388.95241503039 1321.86291368768 1087.51002915168 1094.95667893931 +DTD1 10.1199929505268 9.2462312441433 12.0344244167317 13.3523667738941 +ARHGAP4 3.72390784167576 3.55214653303536 4.76327926806366 5.52365956803669 +SEC16A 21.692720742859 19.7828680658911 19.9199433914636 18.6485118941923 +NDRG2 426.327078699551 410.40205785834 497.313623224112 490.962109473413 +ACADL 57.6279348342202 67.5778634275052 95.9954844887053 95.8119751265253 +ARHGAP1 29.8561055019898 29.2929024991071 37.5299987228663 35.604027743373 +PPM1F 6.42492807046245 4.91214727386321 4.36698752034975 5.17614871366705 +SRSF7 54.7788221666939 56.8900583028954 61.8211680104577 69.2906695422771 +THEM4 77.1971225485442 77.5783332904371 64.5196052585858 61.89233436228 +SRSF1 66.9472197454219 69.1564120567732 83.030324222926 86.3644350673638 +PPM1B 34.3770553355863 29.2984634431719 30.1595835863183 30.2870463812903 +PPM1A 48.3342136581773 51.2964857165377 50.3193760686842 51.8230601237334 +SRSF2 99.3912241150377 101.825089167873 100.848799151579 100.454372164283 +C4BPA 868.398291213353 925.42956307545 1305.18147323815 1302.42096015856 +USP47 18.6962658261789 19.9728302203766 17.2957059687319 17.5946707265597 +ENSBTAG00000022205 126.374436751481 134.518955654307 76.69362825283 72.799247093856 +DNAJB11 39.1649196354961 36.0327537875175 21.5198294338515 21.669850226013 +ENSBTAG00000008564 48.6573800792927 53.6086465645478 126.695465233359 116.944280508725 +PPP6C 16.8918471797716 19.1847040052265 22.8877714004926 24.2718321671767 +ZYX 37.0754172798721 33.6719648011908 34.2737308688148 34.8908231116317 +ANXA11 22.2285017038063 19.5587233692368 23.6541673795234 22.7619091734793 +ANXA13 203.750699406579 210.824271781609 217.552515373933 220.471809140069 +CISD1 79.7726256101505 82.3486714046288 77.5615370611229 77.7433182222355 +UMPS 20.2532185334857 21.7589611812923 20.3611960851864 22.180822702914 +MRPL4 33.9667821111815 28.6032657931341 25.7553356077485 24.6127827036147 +ENSBTAG00000025760 39.0288028673365 39.5129247484177 69.4692472890008 67.3034185131852 +MRPL3 41.8840875012297 45.4245593859166 49.9878059987069 50.6518660135045 +SCRN2 13.8925265228457 13.9674148118253 13.8460621137794 14.6772212926173 +PTPN6 21.4100404840134 17.3855930881567 29.6525937791027 25.3892490370881 +ATP5PO 166.719207918648 185.498918508729 176.716666098354 178.619746289059 +BTF3 243.995919849111 252.095720967703 284.066063535482 287.484576295899 +ACAD8 141.472729413469 134.247959479837 179.943110069442 178.434124784149 +ACAD9 9.68817867241119 8.23908175008195 8.61084073155634 10.1843126422223 +CYP2E1 1835.04753204953 1868.54273657555 4069.21205714596 4053.379533667 +NPTXR -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +BAG2 5.93602412871786 6.30944260256545 6.69200528766228 7.88794945830727 +BAG6 45.6395495523408 43.288093577168 40.7841212593621 41.4937906793189 +EPS15L1 6.10039041661555 6.4041975308741 6.69931766909498 5.71988267777854 +MYO1F 4.95963818654873 4.92318392277188 5.58176887805038 6.18702651041897 +MYO1E 7.00806366858247 8.26899307209221 5.392979257911 5.4982026878874 +MYO1C 22.6463084693309 20.5654786032694 20.9596580307528 18.8457486692894 +MYO1B 80.7786173329754 84.2432126293212 107.943262689484 105.090572404892 +MSRB3 67.4087793862751 61.6353320153419 92.8777023295648 87.4701387694682 +RPS7 702.574737317351 702.6101852007 606.073466384682 599.981479430538 +RPS5 729.993028498007 661.630845988332 636.758990856548 639.055300954126 +RPS3 740.606356649539 757.051364220655 699.041867308351 703.615112817368 +RPS2 1617.52103347076 1511.45299461047 1244.96296604917 1259.56387051812 +ARRB1 5.12630579483302 6.65033958064044 9.96834669593266 11.77031853134 +VDAC3 116.347937195268 117.532880125573 104.938248399075 102.016541403382 +VDAC2 68.6394348764366 74.5765253938946 68.6581588388352 71.7976393942272 +VDAC1 145.519667261676 139.54561575613 137.291461498404 134.064338702345 +CHMP6 13.5824165437818 10.5857283177606 11.4149421044129 11.8651864589396 +RPS9 545.61997769218 508.405120927999 470.016153240504 470.448297127517 +RPS8 1210.9805966132 1188.96587338987 1058.99936402095 1037.43707172544 +ADI1 1024.10879625059 979.475443500323 933.674997711211 915.325207630376 +ATXN1L 5.00185845487956 5.6911188377407 7.72628385398004 7.37544352127196 +GMFB 13.5416729683807 15.7850612256572 19.0944806509045 18.5023618884103 +GPNMB 115.227329549535 123.110192544982 140.43168999246 144.10209504583 +HPF1 31.3007478467807 30.1136885205977 28.2504400771294 26.0033304925835 +PSMA2 80.1726068467046 86.2428600372228 69.7787284706752 72.5406843005262 +PSMA3 109.596445113318 112.32916615502 99.912943180605 101.92405326643 +PSMA1 82.8517588406072 85.0509263181308 82.2619607008741 78.2731237892882 +PSMA6 105.204411361905 119.895956636583 120.850368223614 113.396953794034 +PSMA7 178.312753646554 191.452163133474 151.221512915762 140.850146658638 +PSMA4 55.4410212462756 51.9305655113369 54.3587417167831 50.3525738926555 +PSMA5 80.2610098308323 95.2927793486028 77.0145836865966 67.1797233436214 +DSG2 16.2514502586404 16.4530862110991 20.7457687358425 21.8495010297568 +C2 251.183988483194 254.183673445657 318.265328258274 324.379805688705 +C6 365.2297364725 381.977668759816 504.921962589699 500.435083961504 +ENSBTAG00000038540 174.507427025873 187.684541479802 242.317963001166 230.188467846836 +GALT 64.1494282539513 58.1175836329367 35.8603128146891 30.9725208563217 +HMGCS1 430.110003956077 457.274349744887 142.879224865808 145.95583101321 +HMGCS2 1360.09145336772 1369.05777240643 1515.46275306298 1508.59412842439 +PDHA1 79.3779390001048 76.9297402192079 70.9829275790784 69.4563416095573 +COL4A3BP 17.6908668270604 19.0816902109071 28.3390494204734 30.0991661700921 +SEC23A 29.4797222398034 30.363061553092 28.0021646615805 28.0625393454352 +MGLL 197.373426947179 192.357953825692 161.897896688479 148.514338289689 +SRI 42.361949627163 54.9492167630345 60.3190209314406 65.2848217739431 +SORD 270.205064622654 291.44179011057 343.773034246005 346.803105495147 +GALE 52.6608093618216 51.7787787717443 26.3245360872852 26.2208112485834 +LGALS9 38.7022804674686 34.8558668050426 46.3471977609061 48.5793347499184 +LGALS8 57.5592907932021 52.0369600285485 93.4088235212831 91.1536627271034 +CS 10.1553166109125 12.0959777206 10.9170984919873 10.980623291111 +GALM 159.28871029902 160.68727047157 173.218108815731 174.612673780475 +FSCN1 7.50009095130913 7.91587165290409 6.57361944414281 6.76110084736322 +CYP4F22 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +TDH 204.570701636635 203.1282449823 172.739337406203 178.227512026039 +MYL12B 70.684251328703 69.8407253743907 32.4624943736742 36.4290588686268 +RPSA 931.756812751619 870.143028498824 721.346801452542 718.154569601894 +TSTA3 63.276318109181 55.4154415978116 37.5639238076934 38.4851534115615 +EIF2AK2 16.5233246959094 17.7280846517189 16.9921849303593 15.8675890466403 +TAPBP 78.9714363645159 71.017441624167 89.3716710749899 89.5436883324206 +HNRNPU 76.8994589748686 77.3874251238094 83.0590734760228 84.493297453631 +COL1A2 18.7620337935331 18.7782914942369 2.60818276723789 3.01616815930677 +COL1A1 15.544000426636 15.2259496353233 2.49849109355843 2.37422024603535 +TRNT1 24.5896523061023 27.2081503601077 31.4631907552443 28.9861168687707 +CSNK2B 75.5692235173876 75.5904696883683 71.8578380218151 72.6410590704169 +IDO2 105.412385776916 89.9590632576978 103.974179295223 95.2872829686841 +TMPO 38.055931741142 39.3277371294793 35.1865663338049 37.9842019896363 +C3H1orf123 32.0777008293264 31.1040395932882 35.7761671782901 37.8512733125193 +PSMD11 47.9200429685487 45.2798812844548 45.6214134236566 48.3367746640285 +FCGR3A 37.9750553347855 38.5605837487559 71.0134829968526 69.5548802969403 +ECM1 72.143650109416 64.77946498636 65.9321263235657 69.6119957795539 +ITGAV 8.82887171279355 9.44846950107349 13.0536625487545 13.5505576200314 +FMR1 21.9959094061869 24.5012954946447 23.0513080369683 21.3826105144391 +ALDH1A1 935.592745473172 995.884146092741 1552.11309607103 1515.75188222296 +GCDH 87.1738792841518 85.5316840069647 101.387962341253 101.510859908573 +ALDH1A3 5.64865137065466 4.79069763741386 6.72260964837829 9.91792612433698 +AP3B1 13.3656489859327 12.9551344888718 14.0149546260849 13.5401350425598 +PCYOX1 105.275324016118 114.485608075133 107.984942172662 101.521892450314 +RPL24 571.034153998848 612.205194346373 632.690719381334 625.03498413353 +PPP6R3 35.9051048005352 33.3288906768903 39.8729525403489 40.676972813933 +RPL26 864.785225113768 886.187799281544 871.631861362422 868.416269551763 +RPL21 316.754644874162 323.389645389644 303.715414494177 314.114304320264 +ATG3 37.6656207682015 44.9080354862586 34.279951184147 37.8783497815283 +ATG7 4.38240511688324 5.84590437677476 6.9494550669418 5.61521865483145 +COG1 13.639361490915 12.0999739570515 11.3260963052449 10.5020723071296 +APMAP 89.3343464085615 94.30022276456 91.5312498723775 92.086425000116 +AADAT 25.1483816241629 24.8519976346109 26.9309824814053 26.442166678222 +USE1 51.4294604903283 60.1765270531091 49.1277795881554 49.9988075593112 +PIGR 47.4508901253815 45.9964799547413 35.3139557338216 37.1326118916273 +AADAC 254.608729097143 294.194294793586 410.273286528726 411.094673258425 +HPD 1609.86860738803 1530.41465600232 1885.39602677006 1901.97124798333 +PPP1CB 55.7180068645539 57.1411058658544 58.050626878217 61.4611614284492 +PPP1CC 37.4958897912851 40.6726519889643 44.2449129009937 46.7860991685697 +RHPN2 10.1968036057979 11.6541108172412 10.0796353539341 9.51736120928534 +SRRM1 37.6030479314829 38.4610706842608 46.949207413138 47.4520975484222 +ATXN2 15.9546602949945 16.2198935684649 13.0477042487259 13.4168434349994 +RDH14 14.2582461984711 13.0377738890703 12.577447618541 13.870371176805 +PDK2 65.618326759518 71.6522997338741 68.8863414045609 66.5288104899801 +RDH10 36.6096671299302 41.1465901425207 50.3347806756139 52.4667606678236 +RDH11 51.2678116560163 52.801759134781 23.9891310691885 21.5873875975242 +RDH13 22.6381312953249 21.9405492164773 24.7677289276237 25.8450927837806 +COL6A1 10.2379726872613 10.4024422531145 5.8373852036873 5.39650750882964 +WBP2 74.5837434890667 70.7229789921074 82.7781812489833 74.5042358693879 +COL6A3 4.40249022506231 4.97184519162813 3.11141164426329 3.07482734780711 +COL6A2 12.7096336327775 11.3580206462373 6.57570569374211 8.29045477401882 +ALPL 18.6394950921827 16.3611869889522 18.8094824607056 21.9208270077026 +PECR 414.842936602753 437.547485913324 386.810991514815 382.650118649294 +ENSBTAG00000005501 20.9531418186579 22.1767942941081 30.8568907869777 33.317244513808 +PUF60 41.477865961804 42.3973298543242 39.6817495693424 38.9237537607181 +FBP1 574.579417850847 566.597142203925 500.702340847176 482.937470861179 +PFKP 3.97574182831845 4.27035364337124 3.38902086432137 3.49340898861389 +PLIN2 53.9883017941491 61.4161596310083 27.9160570319036 29.9101523124655 +PLIN3 130.301408182324 121.556212525784 51.8310573286456 50.1782305248031 +ENOSF1 43.9660752689743 43.9641205830451 77.8263728282365 70.8405281473833 +ABHD6 4.33372932324261 3.63360209075637 4.67912867813906 3.70302731934926 +CIAPIN1 32.8378958258149 33.5492800467287 15.9459282099327 16.3022834411983 +CLEC16A 3.18806664069073 2.90602570420109 2.89940833099522 2.78264378850015 +HSP90AB1 249.716229252302 251.364238673861 178.283515811036 178.013155386288 +ABHD4 31.0562588639675 37.6513155719439 17.9113468368529 16.4438618647233 +PTP4A2 123.824275391943 135.941912650309 163.50034494997 157.999420405745 +DNAJC12 32.126825605274 37.0907149915797 43.069077810646 46.8123644844507 +UBR4 17.2151142394216 16.6187141961038 14.8640583771896 15.2541794262567 +EIF3CL 49.25165398452 52.3035523472004 53.9329387407341 53.383656091667 +TWF1 16.5102184705338 17.9716299767002 22.5344545571012 23.0384357652262 +DNAJC10 15.0797600889161 18.6007863012657 17.8393409115298 18.5873043199192 +MRPS9 13.9970227097976 13.4240682494838 14.9494129343459 12.024910571851 +MRPS7 25.9447499666861 25.7469933063357 21.06017231318 23.5965106082411 +DNAJC11 20.5029598641322 17.3228732375999 14.9838276563141 15.8382574311828 +RBP4 5967.76038236905 6099.31389604907 6230.22069356017 6098.90167706187 +PPIB 723.312645697793 682.785340930253 580.843056091039 595.887273512694 +ABHD1 96.4918776593927 91.8664559836183 29.8261210946478 30.0180637874485 +NUCB1 120.700896478678 111.907271672616 100.832991980047 96.6951741258703 +EPRS 33.0887381658401 31.8798461330216 28.4049218299778 28.6346441706269 +HSDL2 181.38570753927 194.184316833277 107.273360945242 107.043769208669 +KRAS 8.88342681297615 7.63573817915969 10.9867587981512 9.07964813911485 +MLYCD 50.6561570093813 44.3326414819259 26.9722571417059 26.6886299308247 +PKN1 46.7114249652488 38.9285117926529 38.763735211262 38.0104603204511 +PPP2CA 61.5556430937443 67.3949285654725 54.6325943521651 53.1213773189854 +ARPC1B 73.7568503872717 72.5881502768215 65.2382134429366 63.7549936447636 +EIF4G1 80.5218124185433 80.2805056359633 64.6725398159867 65.3623329869332 +ACSL1 368.112494780259 387.178926148645 144.79455005561 147.064456570313 +NDUFAF7 7.52496955750774 8.32705204783077 10.4132046189362 11.4009176917736 +ACSL5 368.297895356746 383.247967283847 400.297310486723 398.552218982482 +TERF2 17.662169508637 16.0210553148526 16.6807779175219 17.7546789533843 +GRB2 74.6309086268571 80.0434604870335 60.0214174691101 60.5970437620591 +EEF1G 291.36249942086 309.768751218964 296.733978224553 294.079025404285 +ARPC1A 97.5607102703614 94.8690247451049 100.842335413608 103.141354357448 +PPP2CB 51.67897775882 59.9107779367921 57.7863573885494 58.3065222254995 +RPL8 508.380539549032 484.521218108231 385.942473618182 400.865863736408 +RPL9 896.766070287843 969.982613925704 1056.28866374485 1034.89909191766 +RPL6 633.545612819896 633.173685477536 604.326046780784 590.417382436973 +RPL7 523.083913139424 559.951100504097 496.707070611677 517.849063889666 +HP 3868.59646724715 3838.35544080375 264.244258133973 257.209546653513 +RPL5 619.638685896814 667.410947929764 680.354006772953 696.229254150104 +RPL3 429.314461023182 416.181672891254 365.747324507535 366.072952460585 +NHP2 27.7507923957511 25.3030815075719 18.8864552482127 17.9448150904237 +SSU72 24.0145507269137 22.8846181348975 20.6766451642935 23.5699025808855 +NCKAP1 15.6915139524391 19.2721551308453 17.5277772103901 18.6862123458346 +CHD5 0.378102524004914 0.277347779584312 0.39680653424967 0.42773704715698 +UROC1 201.457209135687 177.050628476769 146.499157245264 144.017319999247 +CHD9 4.54234158603504 4.69619371680298 5.93970001308576 6.27440125383703 +TMPRSS11D -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +ABHD10 19.5439350386652 19.533711635551 23.2566983646907 26.2108663513552 +CAP1 72.8687530446111 76.8221998309333 72.5373957549484 71.2503270400512 +PRKCA 5.09244307098381 4.31778878768765 4.99636120828907 5.97899478296229 +SKIV2L 12.0042161414751 9.45203937793682 8.29091543472455 7.90382050627135 +ENSBTAG00000005315 196.502441800101 245.22808468008 257.64610484036 267.017390460218 +RAB39A 1.45532118357607 1.89465251884894 2.90793954890221 3.52892168394406 +FN3K 10.0688208975768 8.91454082385184 12.9485655881726 12.9042066912005 +MRPL11 67.4877451318734 57.3812050353769 67.4525548024933 65.2623426214753 +MRPL12 148.581160630199 138.665637474197 101.692703713727 90.5253972382838 +MRPL13 29.9836615930842 32.217943149318 37.1485529310395 36.1921540101403 +RAB3GAP2 8.75726440597961 9.35878555211703 10.7207210586656 11.2961546964791 +MRPL15 17.2317586553914 19.0174344408328 12.8072137046096 15.1238358298387 +RCN1 352.890696935056 392.648364549373 410.183739315858 407.770719632824 +RAB3GAP1 14.9668537355672 15.8708753370683 20.0740834422929 17.4350555661915 +ARPC3 107.245848817019 116.890201348133 117.984461622334 120.270662887323 +ARPC2 169.957965551906 164.642136217688 168.486993526044 174.638428369575 +UAP1 57.3188287319017 58.7075781903579 44.8441951810766 44.6715568790319 +DNAJC30 3.6368142500685 7.09249847576193 6.37526145625454 6.16885582041988 +ARPC5 39.8563654294052 46.8557632520326 57.9951658633482 61.8057810213048 +ARPC4 59.9963861123397 54.9973824792684 64.7073693772188 57.7466353097144 +POLR2E 67.3291227604825 59.9322030902188 40.8544285197128 35.655486346523 +DCUN1D1 22.3224057903124 20.6907485043157 31.5047863808962 31.5349536950956 +DAG1 25.7823265513916 25.0401491478302 20.3411529158566 20.4433583268799 +POLR2C 24.1485653338872 26.2655012662215 24.5130257931867 22.8269339573027 +POLR2B 21.7880033338179 24.0114758600295 21.363867136751 23.8315453716318 +RHOC 28.9361741442778 24.4660561733974 22.1002086014252 26.0896764591845 +RHOB 35.5143141084113 32.8345744573365 32.4907890135896 33.2458594277203 +AKR7A2 110.983863090528 102.875722660029 111.614484692782 108.100751801645 +ITPR1 5.83356220902141 6.30554987104384 9.20075907792262 8.26569609353107 +RHOG 28.3443032375148 26.1366599459765 29.0268602924981 26.9600726792915 +ETHE1 144.787538662894 135.057176530301 124.142184386529 126.561358642919 +MPG 32.3686297144552 31.3954726569319 34.9807382722311 33.4946155212162 +KDSR 18.0507484858702 12.944970875173 14.0456776062905 16.437590609634 +TLK1 28.221108176552 27.4471657066417 34.3893197878184 35.3994394406772 +MPO 0.638537569145182 1.6048407108389 0.776611274284478 0.609909899586089 +MTTP 106.952506694673 106.604276279429 71.9439708477298 67.7793469094763 +AIFM2 17.4423658636693 18.1709026898264 12.5515593645162 12.8320996750878 +EBF3 0.105236049814663 0.545542665262452 0.135058347300121 0.267658174938101 +AIFM1 79.0677093147206 79.2641055553824 62.6734336633198 66.9346848592757 +AGO1 4.82205265695339 4.6541461135091 5.15318374644362 3.72644594375745 +A1CF 39.6551599778483 34.8880001594435 56.0678383295113 53.4949335447586 +AGO2 4.57843423254205 5.06374578977108 4.87232199665973 4.39429112233587 +GRPEL1 52.1368211193569 56.8334213812845 41.3282000306447 40.3287425691148 +GAMT 662.985056779826 592.468517715923 762.581010565525 747.642269332419 +VBP1 30.2687663583794 31.3624446313768 30.1849557753635 33.7541099629333 +FAM120B 3.75800869902227 3.85112316196843 5.69850299555534 5.34797934175275 +FAM120C 5.07031880992206 4.11046302992319 5.40716488727401 4.20957181745709 +LAP3 105.119749606569 108.211017385905 101.19351292897 104.685754505682 +FAM120A 35.4588492990109 37.1603461774973 31.7367172020692 30.16660675632 +MAPK14 22.7956165603384 21.9694793577163 23.8655944228792 24.4572592344419 +CD302 68.2378289404061 74.755195136137 139.84932508478 136.189014398459 +GADL1 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +HPGD 11.8169980706091 14.5307655207829 22.475184872186 27.0347799840668 +AKR1B10 19.24486696767 18.9340282995295 52.3117831932445 48.4616353939086 +OGFOD3 12.901530611645 12.5200708738938 11.9865471532262 9.82260308949049 +IQUB 0.00402581315982881 0.130551186661855 -0.0015762168067058 0.163005705537859 +PM20D1 65.2139899160153 64.1278109242474 54.9867302077062 58.2476887933487 +CACNB1 0.722452572994927 1.27686952110553 1.10904994126225 0.895125405243225 +REPS1 11.0862189497719 10.92062438615 11.4509555556661 11.4841834076827 +ACMSD 154.468880362731 153.477281319784 54.2309248175533 55.112044338842 +NECTIN2 72.1444960153682 70.036211875307 69.0771971851763 67.0017480975632 +NEURL1 0.621756635062024 0.539265314273631 1.10629701361336 1.28538292732688 +BCNT2 27.1162704711526 25.2898187580256 35.8024982217088 34.892318768884 +UGT2B10 69.0900923220943 72.903006958683 45.3353525022334 42.4101598625752 +GPN1 10.5427632921661 12.5847083350205 15.5297833580984 13.8273108856277 +TRIM32 8.14816919344869 6.88474382428201 5.60153763952083 5.93532810369625 +S100A9 5.64056218152131 6.77578612282133 2.03470144737551 2.61471102953769 +RPL4 566.055356988393 578.653437594366 575.785243223726 599.372268006608 +DNPEP 39.1460493286512 36.3399231108868 31.9352201938593 36.3646146399634 +RAP2C 35.2619300801374 33.1605461501772 60.3754221772593 60.0628661879753 +OLFML3 19.7915830847905 20.8743221262631 22.2022161051959 24.5536494315336 +FAM49A 18.7937695205866 18.8163081726435 21.1226896212602 18.1786365115365 +FAM49B 23.575391225476 18.9728664628644 28.5359265423879 33.4361731851645 +GGA1 9.85841620604143 10.2907614540323 9.09475337856103 9.67816854108533 +USO1 42.7714455540291 47.3149698623466 43.7967294804329 46.2263769146741 +PLCD1 5.98067498812222 5.96451651421754 4.24242057083689 5.47422033864012 +ADO 7.97454918320147 5.9513471127042 5.2825464211403 5.67628502544168 +ADK 191.390449533644 206.998058276329 236.563198952226 235.115068841514 +HIST1H1C 5.9217792738612 4.95524693721065 3.08599686608936 2.93740002519881 +ADH6 1105.43081797987 1116.25050983947 1266.06451985291 1251.73708446904 +ADH5 174.76512208266 185.888757103885 171.288369593734 175.091193938471 +ADH4 627.747730143551 665.047237057203 974.081942508456 961.472166593059 +TACC2 0.770287877312979 0.684999726390006 0.35643197729882 0.296964381205269 +ENSBTAG00000046172 106.818184222524 111.685602371835 183.042220193776 183.496149676734 +SQOR 87.7011716232612 87.3282444680352 81.5827142810118 81.8866299413566 +PRKACA 29.5060980856036 27.9793635411781 31.8585724658279 32.6768098867138 +PSMB9 15.9025727904202 14.4797083105454 21.7870823605466 16.800394484726 +PRKACB 11.5368562072577 12.2495657531745 17.036479975094 16.3751071270207 +PSMB7 133.75341334523 127.51549048811 113.975164470229 118.59431503862 +PSMB6 113.535773436955 121.379826981675 102.487633671618 103.578500276761 +PSMB5 67.6175240591193 78.6933239697642 60.1992832968828 61.1840823463543 +PSMB4 157.511104185295 152.768294949916 143.155835016009 137.435626255964 +PSMB3 105.742052116652 92.0603001724571 93.3708644729009 95.7050555465877 +PSMB2 123.457762308973 129.473826287437 116.664015972097 117.876040621308 +PSMB1 145.740161313837 141.687848524893 145.508168235908 150.388254356633 +HDHD3 35.9719533342262 35.4537406248179 36.8845295020537 36.9346573441944 +HDHD2 12.3029949121922 12.1217706321042 14.456566910412 13.9822447076885 +CAB39 16.6656839740857 18.8139458413882 17.4463282420011 18.0365077258724 +HDLBP 99.2168803166131 92.2345142229552 67.000123067042 65.5173770809122 +SERPINA3 801.220767771298 803.401401930203 633.71608220141 643.908202017346 +HSPBP1 9.79761074280596 7.7060819034066 6.3271465466497 6.32309502848743 +CORO7 3.0891970219448 2.81317627439183 2.83680531744018 2.61290698816854 +BCL2L13 50.6869633684315 48.5132932256727 30.8973674153838 31.1988647512833 +HADHB 276.497268041029 290.311923822831 252.75831039752 256.299083958476 +ENSBTAG00000046008 1.38094178205221 0.840426513979766 1.57904220415248 0.085804335057465 +HADHA 271.167248080357 271.004748711113 182.988948186126 186.167076379816 +SAE1 23.5463571125196 28.5815712111712 21.5115557599852 21.2545662398848 +NUP43 5.20859465265674 5.50868915258357 6.34510652934563 5.67647582555492 +STBD1 131.775625930627 148.520648358928 185.709447638873 183.471012989348 +IDNK 154.566391641516 166.213443274996 214.124991055638 192.598325547537 +ADRM1 52.3617709637931 43.5686668195816 43.7949505927479 42.2439074597917 +HSD11B1 582.464906368977 615.231975756486 903.396755604835 913.099744333952 +TRAF2 17.6922565355256 16.5567600933531 14.8677082484315 15.174662414789 +RMDN2 52.2186300421565 68.0383837700869 113.26462341627 114.71846490206 +PGRMC2 124.391304672086 134.20384464969 191.065494933781 187.035785454001 +PGRMC1 283.032304612449 306.822427791502 403.905526236531 409.085608539176 +RMDN1 40.6497431302991 38.7777801905708 49.3162426777265 44.5241622205645 +HOOK3 25.4922185969054 26.5875028080602 30.4837901483831 31.9271816640764 +NUP160 5.44806262951116 7.3309970552893 7.62475252103354 7.78738925391181 +HOOK1 6.53856480972397 5.85913656015185 11.7737274045939 9.92077459520354 +TMPRSS6 82.1339306719672 74.7704335353574 91.260050162965 94.2966731132863 +CRYM 7.07309792439572 6.89898178087216 5.10337147998345 5.32079976827509 +ESD 75.6442538453343 83.3345118532909 87.4341711118774 85.8795136051105 +ADHFE1 42.6363219154336 38.0024047832191 65.3554079929732 65.808507216216 +LRRC57 7.10907325443469 7.84034005052354 7.44318522111976 8.18365542362289 +LRRC59 35.6563096465125 34.1620778773981 29.7593149806825 25.9955727305129 +ABCC10 2.47236758427963 2.72568275498941 2.14127736590441 2.41650266717104 +KANK3 3.88160768562745 3.37206389016101 4.57182970077055 4.92008891661378 +COL14A1 10.6822852963128 10.9464837673729 14.6873610110264 13.8831736209655 +RPL30 761.559800967068 741.768290192404 721.083764661762 704.659336934124 +GNA14 14.1090563149206 13.0636652279344 13.7822098527049 14.0784654205362 +GNA11 23.3086519549469 19.7505644650818 16.3744419087467 16.9182240811841 +SDHA 342.895721620255 328.645028155033 270.644392605132 271.563817742724 +ENSBTAG00000030683 4201.19554469149 4486.69776611606 4712.05225597502 4684.59907221519 +SDHB 240.2926032366 238.48797808147 219.156895752741 218.100336343922 +PPCS 12.0715340682994 12.4629526563177 16.4991276565095 14.3552054709709 +SMARCC2 13.4757062113739 13.0785707339008 13.779148869123 14.2056171389136 +MOV10 21.3615481424063 19.4542587631743 19.9166720442971 19.8599920845002 +AP1M1 29.183002953371 28.4627321390151 34.7620874939573 36.4914966220525 +PSPC1 12.2012434006219 9.33301345103818 11.0509936320832 11.7103926257532 +MOCS3 64.3243285933029 68.620939433399 83.9104604269488 79.9182065177737 +MOCS2 73.5970258125575 78.3834013340148 84.7420648538138 83.2626861669147 +MOCS1 61.2719436983883 54.4532836132022 59.3588543754456 57.3641808320027 +DBN1 7.62062667354876 9.42531076114656 3.93402127945625 4.10000182254912 +EEF2K 40.1691060165791 37.2196537110254 34.7725108011912 33.2447300554713 +ENSBTAG00000017938 10.4744885422073 10.3479477514345 12.0141035629637 11.0443097772425 +OGDH 73.6117446168559 68.6380738395411 28.4659169689294 29.0994749865104 +BLOC1S3 4.08576563460671 3.00180422321126 3.00658915148632 4.8083988238156 +ENSBTAG00000039356 7.30691844591151 6.55009685047002 16.3881140889242 11.9274098108731 +COMMD2 5.38576040064327 5.35250177679201 7.20317757835002 5.93599951242827 +COMMD1 20.3735454782713 17.9100258321285 17.1067247381315 22.1357017731009 +MIB1 11.2969217388449 12.6857075332999 14.6376093514358 14.8076575661683 +COMMD5 14.9729052768571 12.0119703280403 10.1518732721567 10.6240689329861 +FAM114A1 10.9614110026776 10.6768022497942 14.9010459406044 12.1095165055568 +GRWD1 8.13231664985954 8.50209199369757 6.91781807161184 8.18598869761708 +FAM114A2 12.7070834818734 13.5273777637497 14.000301626201 16.5049843578312 +METTL13 4.66237668907224 4.45263582848967 4.22166534269016 3.34234547634677 +NADK2 54.8159931271154 52.6332284940626 47.723223058269 47.9553164239419 +C8H9orf64 14.5302311481385 15.1689462703979 15.9533725986414 15.6793108137285 +TMED2 250.98492168902 245.229752263095 249.936636136819 239.138468221124 +CAMK2D 18.7884764987695 16.7699130914659 17.4368419615483 21.0532777003412 +PTGR1 728.696161850511 750.221196300767 495.366183414484 501.366318588195 +PTGR2 97.046283254187 106.374231616666 124.486181953854 125.05017515939 +DNAH17 0.0109092959600218 0.262945783363648 0.15619315768194 0.101126162192876 +MTUS2 4.31718926531321 5.54641885151013 7.38959579507357 6.88167947570886 +MACROD1 71.3409101946829 56.6765415914034 61.2466842310515 66.1484926170904 +COQ8A 23.9487750736404 22.2144870984009 20.140197488807 18.2001640230715 +ENSBTAG00000032350 814.833615049731 862.160755335367 834.393616949251 846.807463464239 +CYP3A4 146.068094305871 148.678559492607 209.960572459571 215.552890791339 +CYP3A5 2650.92568427163 2822.95728007586 3104.9676213905 3065.56732713001 +UBE4B 14.0926461344646 12.3794305253518 14.9016206806154 14.6225200903442 +UBE4A 28.4702742009415 31.1338448614896 31.9628644503406 35.8269852048431 +AKAP2 20.4793594806008 22.9233539157229 22.7779453437442 22.2099296365008 +TUBB4B 112.093821930856 102.462282787532 44.1243213418541 43.9310024417296 +TUBB4A 217.162920683109 199.26521356582 116.15526810975 108.810364912596 +AKAP9 7.4913571170672 8.7323281105844 8.85776793859657 9.42303492817262 +EIF2A 34.9875734942932 32.0505331201576 37.0853447783662 36.1133229327545 +MTREX 6.90808150195829 8.32357076755438 10.7170103796345 10.0672229266973 +ENSBTAG00000048013 331.754579222598 359.827410382149 304.035714488791 310.334461003324 +STARD4 101.605810464958 115.698789576689 90.803439582177 93.4816079378502 +STARD5 20.3422620375773 20.4404606723093 16.5704862916314 18.8236605467884 +CAPZB 52.0510055090945 56.3445745451837 59.6470091326416 51.4380298805275 +ENSBTAG00000047632 0.0768529813312971 0.364114005526894 0.363463933908203 0.930332115479812 +C5H12orf10 5.00383898895227 8.18684479577235 7.24231241708538 7.4771152117753 +NTN4 0.437671141825327 0.49257043239633 0.389281370404683 0.254815966281363 +HSP90B1 529.749449487542 558.107289634185 273.953517489806 268.078279629498 +TANGO2 14.2002202152655 14.2006518370555 22.39373419956 14.0855878751688 +PTGDS 41.8861934582015 34.2050077643528 30.5413911612852 23.9432920680568 +STIP1 43.8469359741177 42.760932885763 29.9000390318798 29.6895986042318 +HIP1R 9.69122839482908 6.79727210896662 5.96980665961365 4.90301748935779 +PIKFYVE 2.9653036010696 2.59690924386061 3.75056548627301 3.64681689681478 +PEPD 56.2130501761185 53.9755344052818 56.2522569559011 58.0814672888588 +AHSA1 51.4445821432798 50.8848861521773 44.7811816147132 44.6500708064545 +H3F3A 225.303842823568 244.433907480341 254.79898483949 245.838914193061 +MRI1 10.8976568071377 9.11153183309112 9.67317602882818 12.0588202970203 +GTF2I 34.1177433031055 36.3557636248256 37.9522942584999 38.9292289822082 +ATP1A2 -0.0349324249447941 0.134890184156165 -0.00542455267001526 0.00657082332543535 +NMRAL1 62.4420154252066 57.2880298346563 51.4896876139228 52.6963777765173 +UCK1 10.6189688597911 7.62972382477382 8.0676926243714 7.76291448538602 +PRPF39 13.4955095592332 15.5856609733065 14.9433242898817 14.8182053536539 +DSP 23.2482415933666 22.5945403700082 27.2420982167781 26.5315189009892 +SAMM50 47.1562419350304 44.4575168328968 54.5163783747121 50.1480343496199 +RNF40 8.39437492670073 7.41720397857919 8.75947234367798 7.43479091332121 +GSTO1 23.9425293404154 26.3024627671921 22.4249246482248 18.54566506549 +DNAJC9 6.9674834314421 8.60217897859582 11.365013964634 9.59291442335075 +GLYATL3 88.3069651281587 96.3898545694085 166.25009894012 171.481526558662 +ENSBTAG00000023978 3.94359952176421 1.99618469037055 1.96462804870536 2.70838143219408 +DNAJC3 81.4550274854325 92.6973842945913 76.6373671543527 78.099066125512 +EML2 5.82370486506516 6.35287145098209 3.8982812388996 3.95215882656903 +TTC36 174.031450285321 187.41842547038 271.49687537705 271.448599792076 +GOSR2 20.117230072993 21.2788436658423 40.0852849876115 39.3904573502129 +GFPT2 0.259374658927593 0.683549921357554 0.492655490072378 0.774472320831338 +TTC38 51.547947866303 43.584223667273 53.5103979194969 58.9812317792432 +ECHDC3 86.7908655131638 78.8997697344205 143.794159305775 156.892095646374 +ECHDC2 108.868406937957 107.219721131948 137.233129511055 139.514787955081 +ACP6 18.0225880202357 18.4044114256317 20.716893615756 20.8768584237341 +ACP1 44.3739721220789 42.0193985682398 45.7929408149619 45.5636851062907 +RAP1B 31.9646413856528 32.8393258833764 45.9772741268579 46.4082042485821 +RAP1A 51.9239423204728 64.3117082817351 71.8486976076003 70.9906569388079 +ENSBTAG00000016551 11.2351360898322 12.4023476480082 12.2812090084989 13.9183912973504 +ACO1 83.0880251448824 86.2651542051764 93.381209742703 95.4248823149936 +CHDH 19.0566218189403 17.7467915147982 17.9703360727163 16.6044094046569 +RHOA 177.382073759642 171.018922395861 189.297872811329 181.368605583589 +NCOA2 11.40396876407 10.2829911201532 12.9978790945243 14.1935224099012 +ACO2 64.7859019499235 66.3275466812052 55.0700701053573 55.0120885074504 +SPCS2 126.545530609058 141.751704078963 135.340268256128 128.916427250438 +FAM91A1 24.4433677061076 24.7884717307621 26.3538034565623 27.0748405477942 +NT5C3A 15.1841115005913 15.5858111069821 22.2490253608455 20.7390259403289 +ACAT1 489.602002890684 519.86938801814 420.149296258797 425.228381256268 +ACAT2 195.308056900315 191.042368742265 120.170851890242 126.558366653556 +CXHXorf38 3.97441389177732 4.1959472931092 3.31802592472746 4.51454285172491 +F11R 82.6984484302132 75.9448090710253 72.5316115639844 72.8997309283194 +HMGB2 51.1842110024397 54.3047196202446 31.3117852613693 27.0998763019091 +MECR 17.0329859357908 16.0683156676074 12.6503975155539 14.1126923602747 +DDB1 52.0831348656605 49.6164760100048 55.5255128845548 53.2761660866717 +IVD 117.437999517947 109.627657090786 111.084565099932 110.115985742377 +AUH 23.3900962779598 27.3591409144889 35.3077780751563 27.4302775396912 +MCAT 12.5461352503799 13.2412443883375 9.02911962755199 9.01958265727919 +SLC27A4 61.5206797570006 62.372138511593 33.3114214279186 34.3609783602649 +SLC27A6 26.2531260070431 28.4824296877476 36.7413575061241 35.3697280293143 +SLC27A2 257.156239280773 266.881214256398 224.07909068803 223.526861810721 +CAPZA2 31.4458481906727 30.4883806165139 38.9993713943618 40.2667943405838 +CAPZA1 50.1115252174051 62.9045557184224 74.7959735190969 75.6628599928533 +TBCK 3.41929887683785 4.30344695711142 5.30579151489301 5.74095514981314 +RAB33B 4.16796946169389 4.65442274246733 7.02988746440271 5.93145204997593 +AK3 46.173978076315 52.3888904532144 43.2224955032579 43.4933840373909 +AK2 222.537831858195 228.571207549421 169.377551667491 162.904866007264 +TBCE 6.37062376806766 6.87428971526879 7.63402195694968 7.14459950008612 +TBCD 10.6953464008815 9.16509778771906 8.63575910345812 8.54621017739418 +TBCB 34.1965030345606 26.7317587178981 31.3628264049507 28.5980193099219 +AK4 7.76497547595988 8.48970065339455 22.458509074793 24.2310628243043 +HSPE1 518.339663980174 597.560049634359 490.363685148162 482.584072720364 +SARS 68.3339519576348 65.7467356833616 73.2616767797978 79.2576361202072 +PRKD2 19.7995488152355 18.5829753728697 13.2967738649923 14.6057965784618 +ERBB2 80.89987373852 75.3128206333502 73.8438791224619 71.4840881390561 +CTTN 65.3990428902827 61.9350864769601 57.9331811496338 55.6300452255334 +DHFR 64.9888897186434 68.9628591609435 95.4245687849823 92.1335013888862 +ERC1 10.3071484091179 8.68389145227236 9.02271277260123 9.27599868673225 +BAX 25.0920419852159 26.4930656501213 15.9593834684537 15.9404397840304 +PLCG2 5.10690630154994 5.70035796092815 8.76241606701157 9.23147743495307 +ATPAF1 59.7403948290439 64.451186651078 64.2084954758691 65.0835121408842 +EPS8 24.3821329999891 22.2296638669543 16.069631819506 17.964715624175 +LARS2 10.673016473139 9.78328628231382 10.8800006542056 9.55122497171578 +EIF2S1 21.1432263942459 23.3878263474377 24.0586753631992 24.4871269943974 +EIF2S3 82.3343568409042 75.4662431620278 93.795658716553 94.2737314822754 +DDX17 95.9516156630263 93.4600835165741 132.388155939231 142.348444688966 +PMPCB 35.3758346711433 37.3939720549373 47.2488622757306 46.8891259074851 +PMPCA 61.180596186105 57.8924014295674 65.1461047261414 62.4226932622692 +SELENOO 15.6241283341212 16.0015843380694 19.7894652690836 18.683118109433 +IDH2 63.7100190593585 54.6024026375344 31.0630334327757 27.7005770466503 +PSMC1 52.4709142451307 47.9861166886689 51.041744803913 45.5475133112596 +ATP6V1B2 21.1359790167711 22.2503142681739 24.7225445839001 19.5827985136971 +PSMC3 76.7499965778751 69.6110658331639 65.334036418072 57.2325007440945 +PSMC4 49.6387997053276 50.4577133984424 33.3434473424666 34.4901254676218 +PSMC5 79.0577614371833 72.6859298624197 67.7184258642264 70.6957119456496 +PSMC6 48.767770672386 50.5296452135104 44.2002602649418 46.5400024629664 +ENSBTAG00000015330 37.7070103301179 41.0109438709832 52.4032627556581 53.31515053203 +ENSBTAG00000015557 102.867289352565 100.678781285115 126.738517081229 126.690283716048 +ENSBTAG00000044081 37.8830705943603 32.6548551120065 53.3483775834695 53.9060722214156 +SH3GLB2 34.2094202547462 29.7064573099832 16.9732780754076 15.5507250194187 +STS 16.7648229963417 18.5392890139074 33.9867643726532 33.9482829374452 +SEC61B 130.587966017303 150.436116656372 120.475539894937 119.861203337435 +LACTB2 52.3576926784436 68.2593927728241 71.072074838188 78.6027599928103 +LSM1 14.3743750617304 14.4390646788682 14.4515125649412 13.2373131655272 +TFG 40.1194159774449 40.2999752690575 33.1247602075221 34.0978358395755 +FN3KRP 38.535540693097 33.7865150797019 35.5623062263299 31.0640537960551 +NCLN 40.1700305563799 32.9112649248107 25.814929349322 26.3587089058125 +EEA1 20.9674013132962 18.1673895453813 36.9280717367423 34.8614263233564 +NCL 95.9698231659148 100.518140287276 108.489774936337 108.454712677967 +ENSBTAG00000039362 388.480250231945 424.807689435474 198.154153237478 197.074203974707 +LIN7C 15.5862887685137 14.1426833964025 16.8187547631312 17.4775928382262 +OMA1 7.38701301586147 7.86180241633434 6.86279981192594 7.14706472147297 +ENSBTAG00000047986 77.0203361197023 84.2558523740238 20.6928038561653 17.8202310008206 +KDM1A 9.30172116842288 11.3126427454206 10.5845148357702 9.25938497886522 +IDI1 270.362201833483 280.584006333223 135.011942010611 130.74160994635 +SPTB 6.08801362707421 5.21144623386942 3.78665703544318 3.87610964060425 +DHTKD1 63.3244147553428 66.2727975110486 93.0618081233863 91.3521322258346 +OSBPL1A 22.8768394170994 22.9220871486793 31.2454279406409 33.584476519901 +LRRC47 8.98057737837651 10.131740525183 8.18863700879118 9.86037035129819 +ENSBTAG00000005217 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +EIF3H 79.3089899585012 73.5040311215211 89.303623193585 88.5982915814854 +EIF3I 114.088588131364 118.270055685175 124.767273978458 116.937715608197 +EIF3J 42.5741729162025 38.9118403582351 48.6951059364602 47.6481443978879 +EIF3K 115.231566761848 118.623627430059 126.824511803468 127.612939544605 +EIF3L 57.8273192143157 54.2319402431576 59.7494866060072 55.7183666803711 +TSFM 13.9686891135 18.2519180897033 16.1897982700765 15.1866275356074 +DHRS7 631.553718721641 631.205899498994 853.164030252418 830.507528128141 +DHRS4 572.41792066641 542.102037464868 489.384268399516 488.641564846354 +EIF3D 48.1198607156594 45.5329114154673 53.7198989382275 51.8389398727379 +DHRS3 231.244304779365 226.69742993739 221.249647499439 216.903296478988 +EIF3F 72.6156697544155 71.5917933088769 82.9364109834598 82.3791831772733 +EIF3G 69.2070593969054 74.0065986360044 81.0698678143449 77.707311645006 +RARS 20.8739748894315 24.2008221050474 22.8069402991518 20.761825127966 +FADD 38.1021460926764 37.1983485428799 32.2083720857245 26.4745211455088 +ARMC10 18.1187911287447 18.8655705648939 20.347293942896 22.0160351699576 +SMUG1 13.2356235792929 14.6702435707577 11.2596629634186 11.8036902431529 +NAAA 15.887726526398 18.3106008348636 33.4958173186671 32.2878723611945 +DAAM1 14.6005672639221 13.706930717315 12.6164748150137 11.5550958117317 +PCYT2 121.716466203374 115.631321750572 55.7544069989008 57.1663052447836 +ENSBTAG00000040409 3642.81826177629 3986.87109144914 3575.62411687168 3454.83057797176 +FCHSD1 22.9471493356585 25.3236544033384 26.0046791523171 27.4918952242118 +IMPA2 85.7495739784571 81.6195534704444 52.1872870908096 52.7720917328713 +GUK1 66.514401805586 64.3763919357044 58.0703593841949 54.9151054306932 +TPR 11.5879898971592 12.2569382116712 13.4868419935552 13.2109626010818 +PHGDH 101.928876662233 95.8148130423083 72.3439893852177 69.1087338648757 +HRG 1342.28164619526 1333.76359121042 1780.13557248079 1746.00848210092 +NTPCR 24.9108964908337 19.1428315586221 22.1640064065062 20.7274735708832 +VAT1 43.9510781610967 39.509533493394 59.0260163990115 59.1720644944455 +MTCH2 111.825110261924 115.884527472094 112.366252134885 110.352241167265 +FN1 430.834081616661 432.33455174828 677.242235329568 679.837034056787 +PTGES3 132.418715990432 154.456263837405 147.062404283312 147.832727268838 +PTGES2 39.9411175036807 33.1672265822469 18.2522122739351 18.3452192528111 +ECHS1 1205.61006711327 1163.57219939394 1042.55555782428 1049.20223783287 +TIAL1 56.3450968547158 58.0410694027574 72.709964907475 72.2456411611393 +CAVIN2 31.6296313467552 29.883607547196 37.5865845072096 36.4440874861828 +CAVIN1 14.0850433725362 12.2479742130271 7.49097048728428 8.62793411942651 +FUBP3 15.5479965871368 14.0596474726751 18.1669132507592 19.6976462632236 +FUBP1 23.4841399881297 24.9711476727051 22.9956316187974 22.1909544986458 +CCAR1 24.5566795579161 23.8875668126191 23.0142569842389 20.4576296643361 +CCAR2 33.995317551519 29.082968451669 31.7009858687608 30.8887561860281 +MTDH 40.6117352716085 40.6034089044199 44.350907439522 44.8841795260189 +AP2B1 23.1107181255078 18.7896648451411 29.3743842702834 28.4168943672371 +EXOSC4 12.5862740395964 13.6092675346644 8.76499349961407 10.8509333110407 +EXOSC5 11.8808916331351 11.1567770748366 9.79549382102322 9.30801328291301 +HCCS 10.2887267742598 10.6884415570165 7.81892969043089 9.24558891266734 +GFER 17.8253827602257 13.9577194745042 9.6425548002615 9.50871067465274 +NCOR2 6.03487607568843 5.56790995887333 3.88870821636784 4.53334321546119 +CEACAM1 40.1779107926503 43.4760045769739 60.7460595997956 64.2044593158198 +NID2 5.96970818722828 6.23309226046528 4.06582537746576 3.87559220203014 +NID1 52.9705235659317 52.6710046095159 57.2874248309873 58.8771082307562 +ENSBTAG00000015047 536.488203976578 576.252902313882 484.686165649257 491.254333062634 +PLEK2 10.0032463599796 8.75457149644676 6.89251524908072 5.32653138148207 +PALM3 29.808704459807 31.3262350583532 21.2689774526378 21.5923014122513 +FARP1 51.8867570238684 46.4744986418871 45.065665420364 45.1574811093893 +MBNL1 18.2650726150367 19.191090135862 22.142907424981 23.3502274020621 +AGMAT 166.752737503077 158.70550624864 183.733987603998 181.530803921037 +F10 437.338384169004 394.479916044307 522.633054293112 517.582414547523 +EXOG 1.32753091035198 1.87507915719945 1.58554599451868 1.85541389483128 +MARC2 310.519598749897 338.109020323337 483.219565274969 492.097364105722 +RALY 63.9077234222977 52.8815876864748 56.5477237068926 58.2081773292813 +SRRT 24.1202886961495 20.2939036361896 19.2266981062274 18.2342419627984 +SARDH 18.2318179637154 15.0614134243257 26.2706393230255 23.9593411167966 +VPS53 4.84953407154577 4.97056757034682 5.16961324142711 5.39952115018413 +ALKBH7 31.6069154774617 31.1079725318752 23.4388367474727 30.6741048078656 +RALB 19.0190241651869 15.3341738562443 23.2635967284838 22.8923477734633 +RALA 14.8252504548386 15.5583345005018 16.3635644091086 13.9968041836226 +KRT75 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +TMEM126A 36.7925489384036 33.9313812885924 34.0938264468805 35.3674433303855 +PSMB10 22.366296126555 23.612589331904 28.2570801068124 32.3990389745477 +MOCOS 16.4814607154525 14.6645364021038 21.2436162679388 20.2020312348938 +SCYL1 23.9866069970233 22.3846238593466 18.777383072665 20.4583604001099 +STXBP3 16.9095252776294 17.2795852664765 20.4352533962585 22.31052819091 +STXBP2 42.1813176144312 39.7138692180028 35.5165006169736 31.964436423108 +HAAO 459.603924040606 424.946645314015 349.223699609901 354.737072400721 +FASN 12.1832618330706 11.2247034797068 4.27945679990593 4.40423732144923 +SKP1 172.638979476066 187.23836973001 194.932231556146 188.851038986175 +DNAJB2 26.8275140377282 25.2643390314589 20.7258774211276 20.9682715269717 +DNAJB1 31.9466957513415 32.8673759682631 33.3947007333481 31.7801042682247 +H1FX 121.968462071309 112.153540090506 62.4402817598069 75.4370965398784 +CRYBG1 10.1445664579257 11.5679578993255 13.3334724088827 12.3784885028081 +OXSM 7.6228094874408 7.96477625843329 5.50347667809366 5.50196476166338 +CRYBG2 12.1844836645202 11.5961897375428 15.3821940910318 13.9603803800814 +AMDHD1 102.616657806076 100.178802222146 82.2651559352772 89.3076850200113 +AMDHD2 11.0266054969547 12.6368243330249 14.8520323528994 12.2749472031564 +HNRNPAB 58.4931656036547 58.872708391073 61.0977018293284 59.23907055398 +TTC23 5.66273536557649 5.10939575141991 5.29403428620502 5.80502277104746 +CARS 8.63159727468553 8.67099986067082 7.00775758668853 6.64636979257245 +HNRNPA0 18.0590508815221 13.0812366331197 13.7133261420312 13.6802402929556 +HNRNPA1 179.599284626945 185.257107758138 180.665595882705 187.094981139306 +ENO1 381.271673116926 366.544215762049 290.683161669903 297.069573014612 +PDF 9.98823405856843 7.79911837651794 6.78665799142329 5.92236329530247 +RACK1 858.768353483779 863.298892222446 792.30313084731 788.639455047502 +ENSBTAG00000017949 0.498767525923125 0.533024558582954 0.540926003393814 0.800136244720405 +LLGL2 15.7040417050766 14.3229464877066 10.934839431655 11.6243376604496 +LRRFIP1 11.7069059683775 10.7098891171545 11.5718771670195 11.8211079728934 +ACOX2 369.239691982888 362.043238782978 284.378340136321 279.632009330622 +ACOX3 28.564097830672 22.0908326836887 26.9991769038382 27.4157763902516 +ACOX1 160.843721968091 170.113006293914 217.296098160017 221.679804531668 +CDK1 26.8078130719742 24.9661267619084 9.4299068879976 8.75778737238034 +CDK3 46.1012215060919 42.6313076187989 19.7538653526083 22.9339695107235 +SGSH 14.3795799922517 13.5187125977655 15.9800592512645 16.1613623814089 +IGLL1 401.356057836198 354.597367865997 113.195325924581 117.868124772962 +SRP68 24.9280846010669 20.2569535851394 19.1882469479339 20.4417834823388 +ANKFY1 6.35230598835986 5.59461556148715 7.3865616250483 8.19927612110851 +RAP2B 5.7188758156169 4.86010082844554 6.07220289207095 6.0606600804375 +LCN2 27.6448749726907 29.5490425639249 13.9730232499535 15.1713694127732 +PHB2 92.942748182426 93.4374806978708 82.8127531916424 85.9196062696196 +PNPT1 18.1215245356395 19.5717558122056 16.8688779280532 15.0657719684472 +MSH3 8.58071822834958 10.5039161457776 9.48457065554682 9.7880547819692 +SF3B1 52.8328516699784 56.4055522916201 67.4304755562418 65.5551156949989 +PRKAA2 8.33696801454716 7.65058526125221 10.4331557276127 9.35690520556767 +SF3B3 31.046759674103 29.0967761499223 29.5103373226005 29.8734123675225 +SF3B2 27.4038352654791 27.330588140953 30.3499288798422 29.8337281364214 +LIMS2 35.9067484532959 36.7104852570305 73.0056102408556 67.5372220994988 +LIMS1 7.65045437056355 6.72065549017984 7.88575126301273 8.6286388533318 +SORBS3 29.1839945621072 27.478734696872 35.2306324520116 36.6891652272683 +SORBS2 10.4388283587913 10.9216983993387 9.41738676968242 11.218564328747 +ELAC2 11.7342084066535 11.8392185317158 10.4371764324317 12.4229452823288 +SUN2 23.5508062877979 21.558577377586 21.5133400458983 19.8936978070011 +ENSBTAG00000008248 24.5301101133031 26.1418176581525 26.4397802440541 26.4136448100022 +HSPD1 265.176486911651 279.419646945023 217.862220501207 213.880109063015 +OGN 10.0323584694161 2.88025662944508 3.59361781818193 2.69948053858597 +ARHGDIB 40.2843454083653 33.5174894975693 44.9829110964024 46.1503311168694 +MTX2 26.8438511509804 23.6807550888286 22.0346567625514 23.6516316685903 +MTX1 24.2443591345995 22.029337501554 14.985943206831 15.1024374909547 +ARHGDIA 116.136359765553 93.4479564153374 106.138774049532 118.676721255044 +NANS 30.8805848799376 30.631920596469 20.4549926972727 18.1753387957135 +PACSIN3 52.0022154367677 48.918333146788 34.8080003422947 33.125976712411 +PACSIN2 14.7471629387524 15.6295734237452 10.7673856930762 10.7535760149493 +COPA 56.5415738802033 55.1256349911717 59.5736165463659 57.2298175454171 +LIAS 11.4033181279969 13.369431512345 15.6750135607123 12.9808526303874 +COPE 84.0280129674988 70.3895232782106 69.3245758404472 68.7023785018489 +SUPT16H 11.5242636917864 12.9155682746774 14.5472654540232 13.9574394323376 +PRKCB 3.21874393718854 3.94655740230675 6.11051104069738 7.21764276294812 +ENDOG 53.5022302586054 49.6857399257231 46.4330997826011 43.421912315742 +PRKCD 5.00578394864492 4.6918278090674 3.66059038197226 5.34387392539858 +CES1 657.627525020876 645.113744458743 1780.82900875901 1783.12269981632 +CES3 491.326380942713 479.875880044093 346.501787723459 345.556496749204 +CES2 269.345374656252 272.426147883064 399.135434336173 411.244856640026 +LMAN1 143.225437363508 144.70618069192 163.811896775314 163.413612002755 +LMAN2 224.511321710313 211.07428677687 236.22629840472 232.685072717047 +LMNA 58.6718154654327 56.6237587975677 15.0504714839894 16.1063338484974 +BDH2 76.2779815592127 86.5451785896173 74.5052816498982 73.3640631609913 +PM20D2 5.28776860982995 10.0892114703451 7.13084947987655 9.14304234079105 +DDX23 17.6510594072614 17.2421228729002 19.258056836745 20.423728013516 +DDX21 14.1198720265609 16.8848365824287 18.8782007448005 19.1080380422885 +BOLA-DQB 7.11003161494104 5.98707518262986 11.8219558959748 8.60228490340021 +PFKFB1 76.258179950693 83.6738581001602 112.508978482779 110.158386210505 +ASPG 19.8435058719096 19.4333187389306 6.14557250854855 6.41487103899518 +SCRIB 7.56128349348843 7.97634272205834 4.82583808172263 5.61074099781179 +GSTP1 50.164595219918 55.6096606485813 49.9341488774493 49.9782822763684 +VTI1B 36.9612140329229 30.1580886580028 41.8905029070371 43.9724228065818 +ATP6V1C1 12.1531778429436 13.6985132004281 16.1947606731877 16.6816055398607 +SCIN 2.43022472649464 3.15030770131924 4.15087424891336 5.57303135951839 +FKBP15 15.5827501488651 15.182494857953 18.5298122428994 17.9998346070168 +ADD3 16.2284808832673 17.0067107777246 18.8383192029129 18.03258130514 +ACTG1 332.905066429476 323.803491566089 234.933479504726 242.255984963068 +ADD1 20.2769619449455 19.0185220960693 20.8765149918836 21.4507590248491 +FKBP11 119.451402855498 121.106508368478 82.3490471015213 81.9294726730359 +FAM3C 13.8394889891584 12.2064087000794 13.7446799387303 14.284096533087 +PPP4R1 75.9596157508561 77.2259080287634 70.6664219879239 65.6209543658932 +PPIL1 25.7591026693066 29.2239652085702 28.2683682551615 25.6620339660294 +TPI1 174.704116713492 168.008171577484 111.765311584812 114.716460023874 +KCNB2 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +TMED10 113.324011011411 114.806591635016 125.119069048464 131.297657927284 +OCIAD2 83.413192447094 97.8456241248504 119.032188444695 124.304488007789 +PPP1R7 16.5036944688331 16.9798261447558 16.2051725194055 17.3712157210292 +OCIAD1 120.067439339414 124.172598304355 151.718112662913 140.434056160894 +MAP3K2 5.3388304431554 4.08884668809775 7.72950727915985 6.55158883607604 +CCDC93 10.4744142506418 12.2453601138503 12.50153253235 12.8139742587717 +NUP210 6.05924668423472 6.71940654735698 8.41891148576624 10.2328964962645 +PRTN3 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +CTSH 47.5009627819062 44.865042237459 61.009324435394 57.2936768866237 +FMO3 630.985421074896 655.303897016885 792.12018490243 806.071245143242 +IARS 12.5301840849552 15.266079791919 12.8718969246571 12.3387449979931 +HAL 41.9909713317432 43.8608863841128 30.4500124369469 31.9505132265284 +FMO4 30.5709421708989 30.6842007934004 46.9155837815718 44.0697967391927 +FMO5 128.802107549929 142.861212110502 258.182788519966 255.776198154426 +CTSA 81.4948452904226 67.4211591022967 93.401289960485 90.1077900243812 +IDH1 276.10158286935 284.131384009262 173.573685830234 168.004141288397 +CTSC 161.913079057291 162.633117730462 180.553495776479 178.874998814862 +CTSD 205.678730487267 174.40706307611 182.852341247966 187.800623878286 +SH3GLB1 22.4508047043908 20.5707965158703 22.888952815586 26.5118269240245 +CTSF 60.2928988716415 57.2058662122831 49.0740056447364 50.3703117701687 +RPL14 652.679807705753 648.194194810739 652.171425409546 646.210253637788 +RPL15 88.6826231836054 92.3096643628748 115.757066224389 117.153663003458 +CTSZ 419.138065664984 402.824752380718 359.227403838114 357.836325071414 +RPL17 665.794994906517 583.742385133022 609.205365673252 652.60370574181 +RPL10 1629.11999538505 1545.64267134026 1417.58724443746 1396.08223035725 +RPL11 606.158067235754 581.654965716056 501.971887981769 482.140547104801 +RPL12 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +RPL13 305.77090011712 290.842367929273 256.411254453948 262.811767225611 +CTSS 87.1374661748081 87.3507358688656 163.56120889591 162.933867440271 +RPL18 702.212378098988 631.869936608947 585.118214463508 589.927860133852 +RPL19 947.297736720385 943.127688010831 930.633496912332 958.253187628406 +CTSW 12.2892923106459 8.84949421569506 16.6406302558684 15.9989948869977 +PCYT1A 10.5104443871559 14.4420739245679 17.4758176833643 16.8090676593813 +SMPDL3A 68.9682456594669 72.2141212642125 69.2770639943969 62.2882666404987 +INPP5D 4.46326753674894 4.21179296196122 5.93485715572042 6.59390280008222 +EMILIN1 44.3919651026962 38.2498543712809 45.0158465191836 47.5653887747132 +NME2 75.4805917044064 65.6337564557777 58.8593685855017 51.1889279420248 +RAI14 9.42152731551424 10.2252883612002 10.186513309741 9.83680714824442 +LXN 3.10684204894733 4.50859677174486 2.67773532797147 2.56816000323145 +ENSBTAG00000000258 1160.3382098293 1188.6342982147 1379.42097438099 1400.97838591565 +ENSBTAG00000040418 0.401143024675626 0.647887817038831 0.491760196427325 0.194339814969575 +JDP2 6.50449120586652 5.77358417265287 6.58595297804334 6.48798672504579 +EPB42 0.119997791340842 0.345517962994695 0.341370988110041 0.286752507293721 +EPB41 24.1502211857368 19.9720920322015 26.4334434487252 26.8056451704305 +GATD3A 92.3797355579327 79.572467069227 89.76143579413 94.3248888981986 +MATR3 61.3385523843579 63.3652682542377 71.9890652925929 68.4883789301482 +PRPF3 20.9232405079524 19.6467292419969 26.3277439664518 25.3165708540006 +RGN 1009.70981334055 1025.62857420514 1251.79484006022 1245.21256345165 +ENSBTAG00000046076 93.6376332353904 96.1118045614768 19.0096839095121 23.351309018035 +AHNAK 25.4881711501906 25.9997170077043 37.1099321618289 37.310588053659 +ECH1 217.215620382344 224.087469149211 209.067973316987 208.324260089591 +ALDH16A1 72.0006032158355 67.4583150264986 70.7817192209612 67.4528975785357 +CLUH 45.0673846737799 41.2996524527532 30.3326758003316 33.3284862794173 +ENSBTAG00000035915 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +PDCL3 16.8024263357314 14.161232298828 11.0673779124181 14.3469108216772 +ERP29 100.244193595539 101.19492733397 97.4212377828514 99.2194363936814 +PSMB8 36.7597788527108 31.3644167760726 48.1466216974714 45.5905901632791 +KATNAL2 0.483795449667477 0.322483462316373 0.100530990971139 0.112825692968048 +PHKA2 8.81093161280088 9.44103199746286 9.14485053473185 9.4010520837502 +UBA6 5.47864028725934 5.82177630335361 7.30779150636192 6.15168180187787 +UBA7 12.0310860679826 12.0916205932916 11.6505662508943 11.7876444276797 +SFPQ 37.9314505259498 36.591949910297 36.7098017568095 34.4559574072378 +UBA5 18.6438957873492 19.2406562946691 21.1899429640531 20.4580037451133 +UBA2 14.1261367199376 16.1104614308802 16.4785571640803 15.9276527995276 +UBA3 19.0393901520512 23.4313386309023 21.8994107756724 22.332189396936 +UBA1 43.8144925756225 43.6487065496451 42.1384904588888 40.7767772886139 +DECR1 126.997980191995 131.122421049726 199.174434341353 206.392976997819 +UBE2K 53.2466971009806 51.9181751946097 43.3584853348651 41.0952296475917 +NAA15 6.14865145176971 8.0614418672985 8.04844455994983 7.7134769194334 +UBE2M 22.5747642344538 20.3593434004248 15.1468157993139 17.7733067552239 +GNAQ 11.6136991753553 8.1651146204697 12.5257486951333 12.4851346306178 +GNAS 182.618990333848 180.230851206132 153.637007123569 152.001185576341 +MOGS 22.5514292311476 27.65401227448 19.1688474702656 20.0647773668326 +HYOU1 25.8353431419396 24.5033443792191 15.0267089658434 14.423674557674 +PTCD3 11.2462150337538 11.8831089371259 12.1017701609723 12.7301238995557 +GNAZ 25.7453735807559 20.6571204946724 26.2589107385617 25.8059663644884 +GULO 372.75116117371 362.192758859547 454.243951131631 457.682476756914 +UBE2Z 23.2739631750086 20.1547318679898 24.6216289962725 23.6921954214776 +FGGY 25.5682382168423 27.2343244798227 34.3811516543247 30.5311735501625 +UBE2S 39.991012430999 40.1153571360755 12.9786605374214 11.8624746361031 +AGFG2 38.9218893505428 38.6245726803028 46.3295686446519 52.2445772035387 +AGFG1 29.8905730317607 32.1661724141668 27.7553479342287 26.2566141489647 +FARS2 62.5182594287738 53.4562912024214 63.1873219654332 60.9626679280191 +ASNA1 59.4803144964307 53.2220006466034 49.79073160127 46.3226823379286 +LIPT1 3.9019589697194 3.92452291974253 4.81603979414554 5.7161453637328 +SEC14L3 19.8111953403584 15.6694649077659 26.9339398084139 26.132710288661 +SEC14L2 302.579543919248 280.562880510244 276.829413021666 287.845160445533 +RPL18A 491.948714387137 484.796650907269 459.230244182188 445.197980897527 +ILK 58.5036018136718 56.3243148720487 43.8601668501454 44.9838066473857 +SEC14L4 28.6346522556473 22.7050433119988 26.7538670257538 25.4665729139255 +ATP5PB 183.607106690882 202.414225856232 164.942008471332 163.614536956921 +KRT7 10.6143361717877 9.42299404506042 1.52860645229135 2.08860357978643 +GLUL 73.2924055276477 70.5745451668881 167.836154288379 164.708748839296 +KRT8 177.674592237015 170.140068918274 86.0535275560603 79.1073740309155 +NLRX1 7.76482102310629 8.23620489529551 8.61210661625393 8.87229294779666 +VPS45 7.26787784439713 9.04442744394242 9.40974106137658 9.48455216616009 +SRPRB 28.7157409949337 30.0781412260209 22.764330093084 25.6718809330068 +RBM8A 25.9587139117452 28.4121157457581 35.2669408052121 33.56658425038 +SRPRA 122.869913787197 128.816299327919 108.024619751145 105.955011360999 +TALDO1 80.9514908647053 69.2512733279015 69.4089252702687 78.0366391507369 +PGLYRP1 0.306285721166918 0.398309851059885 0.27275694995289 0.532239625935164 +EHHADH 344.673451380902 352.46265992912 317.689864121286 314.444011277087 +CAST 32.1406292401761 38.463799194025 49.236074860295 44.382176544649 +VCPIP1 8.16975718803256 8.10534075715221 11.1247248167971 11.4782877197701 +ARL3 30.3935052980604 28.8393499884189 23.0845329852236 28.7214236264465 +ENSBTAG00000003523 45.2635014371261 42.7833762814734 139.554414607733 140.636760888034 +EPB41L2 19.8859118918539 21.0205346501446 24.9083777377921 24.0005546980718 +EPB41L5 17.7976250172803 18.3167373319711 21.8665658316818 20.0064079418271 +THRAP3 45.8381074333885 40.7671327784696 48.1969785701551 47.7255989676176 +ACSS3 77.1834018320601 79.5635771624491 105.647102529185 107.874260816178 +ACSS2 55.0811633563026 57.3682822866631 13.6384000535754 12.3993797238629 +NDUFA8 60.9726279342233 53.9293113306046 44.2487957140513 44.9480426584674 +NDUFA9 44.6303126581316 44.3811193656566 45.1970755888405 44.3535846590977 +UAP1L1 7.71160104439764 8.39728700353465 6.36327212737617 6.43819322097666 +VPS4A 46.0230925254958 39.3164822807516 35.2361903863122 33.3275845885829 +VPS4B 16.3031079414598 17.4974136812618 21.1547131134337 21.3090912678599 +TARDBP 39.1576302217017 40.8162691932239 46.5156792615457 46.9270754925124 +RAB9A 27.2884943261745 26.7547605043245 25.0120032454061 29.4092355671113 +CYP1A1 443.899667555243 425.353424933626 538.602541270491 543.974061642154 +CYP1A2 1712.94255994408 1695.13136780727 1892.36800791136 1904.7017615886 +MTR 7.26503158991253 7.11442495892321 9.75525307923587 9.4553737455498 +LGMN 403.59885776665 508.113066543034 742.166541055438 681.613138779251 +GSTM1 233.935030978651 231.590878163071 643.684679976937 623.360715109503 +GSTM3 380.175451710196 383.8041405072 596.347855935607 565.102335028194 +AGXT 76.9307419582239 72.7453294967533 76.2014885678422 77.8008372388022 +FARSB 30.1694868322304 29.0886418670674 24.3049468420069 27.8309594923758 +PALLD 3.21342857432873 3.53476526437626 2.09596048920819 1.87866458391469 +STX12 12.2866322632326 13.808164770057 16.0159566206302 16.6778734449686 +BLMH 33.6831024616265 30.3610744835523 38.3951134132686 37.6743452774858 +STX17 8.0090607202102 8.38021024964989 9.42333864618234 10.6331719145541 +EFHD2 23.9406573909224 19.210727800325 20.4579489742126 21.1754495297849 +ECPAS 23.4961957758673 23.0375138590539 25.6029837954262 24.0401182104356 +SAT2 35.4258650293568 42.3125233284582 40.9798580121844 42.6891871517284 +COLGALT1 14.1450218704896 13.6174411602918 12.3686719919197 13.9735242088829 +CUTC 25.8801448189538 23.6285150997845 24.4066993459989 26.1872977101469 +GPRIN3 11.7930484074464 10.3858341729735 8.57716682880559 9.65318872893883 +EIF5 81.2421900161006 87.1618406539649 120.897484112723 118.089344374093 +EIF6 45.4119598431191 39.7629909315891 37.6532730192512 42.4391878569412 +PDCD6 31.0390251542234 25.8189967212042 29.0736401351352 32.3549412353386 +INSR 11.1519635330785 12.5248924547245 15.7292231765415 15.5317652269998 +HIST2H2BE 128.671959967897 128.599399576766 231.28653332908 228.414237336389 +GNE 36.4126998250622 39.3953246059016 32.4425250590848 32.3549412527921 +LTA4H 17.8212107299761 17.3741864401897 16.951605530818 17.4975192823876 +SPTBN5 0.105293397282788 0.311206137751401 0.157412427722463 0.179459705128839 +SPTBN1 85.4342472068267 83.5803913612639 82.7958822141318 84.6962313459788 +RNF170 76.9358965517475 77.6305444845545 84.5153618512971 83.3899372284203 +CBR4 40.380488223499 40.5934013228527 44.8045729189248 44.0926570141464 +CBR1 450.058066733913 437.149207881359 306.72691715598 310.569929892312 +NSF 7.63741313574406 7.97845640008284 10.3345732490862 10.5292007459013 +TLN1 37.8573234474103 35.9340273142161 45.2624396436996 46.4904833967905 +DPP8 23.5670908117968 25.4519293471639 29.9501619230439 29.8021587827566 +DPP9 8.79198936609015 7.9471403852368 6.8205905095014 6.58529839955077 +GBE1 31.0981990876793 30.3339933337954 52.8352902056074 55.8780002476793 +DPP3 74.5816200894726 69.8069259057225 55.4029626596484 54.404525717796 +SUOX 69.9750129098994 74.1447137457669 35.520914921309 36.1279257092413 +FDPS 168.508949393078 166.222491621599 53.9694040636652 53.4189226654697 +DPP7 30.5771144461343 31.5387153515276 31.5244149912696 29.6539651855152 +PCNA 32.3751738086243 33.8650091592008 26.6420266635535 25.2061922983274 +ANXA3 33.3306962685079 30.8335619206099 43.3136361664653 47.5673069013433 +ANXA2 164.723671962807 162.258669502639 113.744222095844 118.605528539905 +ANXA5 22.9553637697725 23.436727937923 19.085321355623 18.9210629732804 +ANXA4 299.63502969593 312.600094901225 361.189262557472 376.995534914541 +ANXA7 26.1461749741735 29.0767347069687 33.5594344150329 35.4497988844126 +ANXA6 327.924598477858 324.894474489593 367.891551743615 361.933220243367 +ANXA9 15.6712182556697 17.5415063290891 15.270935745688 13.9909315383123 +MCM7 30.0771825102943 27.9731848723569 24.0156383886894 25.1037325262421 +MCM6 11.4507999121514 11.6475441556253 12.1865506738817 12.1536835104322 +MCM5 12.895537270858 13.7679272209016 8.99729556970095 9.37542433488583 +GCLM 49.563823447331 52.3842664376996 53.2851860839546 48.7282699955746 +MCM3 11.8043417316323 13.1241478202336 10.0659697536689 8.69323649899029 +MCM2 10.7884756708815 10.9824207040605 6.73530110462466 8.15292782784232 +MESD 45.2073530885482 51.4055365699161 43.2751419493926 42.8911609830404 +SAMHD1 9.87601403936964 13.2224529275359 16.175095705697 15.5717278010429 +AMACR 125.900995217333 119.723871071229 102.420956699298 101.648173571527 +DNPH1 42.3106931787044 45.3957085778143 37.5904857573449 41.3487379287758 +RPA1 25.7446781992929 24.3186990145693 25.4087830091423 23.8092056700958 +RPA2 26.8169652084513 27.176249279213 30.2206952721277 29.9782321054014 +NDUFS1 50.9131433544962 56.870791517286 49.3076230582132 49.8245169840024 +NDUFS2 141.356940674559 148.787701316479 124.765993407787 126.122315402446 +NDUFS3 64.8104079676586 69.6185410694643 53.297872416595 52.516759800929 +COQ9 52.0898490205684 45.5527591500852 33.5681972079694 32.6296167658119 +ENSBTAG00000024700 13.9427368441999 13.3413099439875 40.6443219356815 42.6540704008321 +NDUFS7 71.5767359980036 77.8601813009976 58.0608806354797 61.0962587086881 +COQ5 16.6952559028035 15.6999811317943 13.1497099581853 13.2159938909836 +CGNL1 27.4971722491166 27.427334013067 44.2059628407178 42.4493365316552 +COQ7 14.7282831315524 11.8008751719291 10.873816913233 10.2273605599149 +AHCY 1075.7833914108 1036.32503519194 1362.40216551934 1337.60136587828 +COQ3 10.8836458706678 12.710522410934 12.4853160846636 12.3348080808325 +M6PR 42.4810707223336 40.9331114011853 56.8377046794483 52.2443676937292 +AOC1 124.287122225925 116.969121918782 126.552117326659 128.383423360012 +AOC3 82.752325832058 80.9777292172397 119.063933155219 116.20408669294 +PEX11G 87.2694831920995 75.171215216832 62.4988607596056 56.8685272512562 +PARS2 4.68673332954398 5.30457898459843 3.77833973926001 5.0752129175389 +BHLHE22 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +AOX1 102.733468954366 109.961362564846 806.66820101381 800.38889971733 +CHMP2A 67.677709155545 60.9821193132537 64.4621388507266 71.3742386304634 +DHX15 37.7787950290722 40.5166340313269 34.9127338131303 34.8579132675829 +HIBADH 157.523372682206 174.566175649235 205.09820413991 212.469955999916 +ZFYVE1 11.2752520873893 12.4481622608495 10.7110245059276 9.05496567895166 +NHLRC3 10.5610606562933 8.84949592654071 12.6047495372917 13.6911245627275 +NHLRC2 3.26101405298056 2.97943490053291 4.85714908394091 3.99538498357043 +PPT1 35.7925861702565 34.7568355177783 46.1681445353371 43.7370417071857 +CPT2 135.976064870997 129.548095158476 107.475574550724 100.824230812536 +DSC2 15.1939402379469 14.4662394875957 19.3041072510751 18.5531940536754 +DDX31 35.4863679339364 35.3834299570322 36.3098926016816 34.3104597810253 +NDUFB11 130.868120364589 136.261543038474 122.919297261004 119.22502634895 +NDUFB10 82.2753036274055 76.3295278239464 63.6830130206243 64.6583836833978 +PYGB 3.67985487413328 4.27943505208412 2.93315199885531 2.25689882925156 +PITRM1 11.3557100643103 9.92016642490198 10.3344091410629 10.27083965996 +GOT2 275.627465766641 289.021190595176 244.397354626054 241.278368591505 +LYN 16.2391525757194 17.5909905688496 20.3131284952545 18.9463350468372 +GOT1 56.6022365307647 60.4055243110375 42.5011183408445 43.3046383816003 +PYGL 297.898531330771 294.880177758199 323.649741593138 327.770485002234 +PYGM -0.0769323453192576 0.18923177843539 -0.00517053422262956 0.00684012553343591 +PFAS 6.70939472118538 5.74943018537561 5.04826581328738 5.30314990317455 +ENSBTAG00000017021 13.2822858434524 13.6600779598427 11.8308426531706 10.4426369009846 +SOD2 153.219010653418 151.215867921246 142.052357950188 147.634745414601 +SOD3 40.148183212177 32.4443766784912 28.8093103264457 32.9126527785487 +VWA8 13.6275087382427 12.6862051589027 21.5212763665898 21.9883525283246 +SOD1 1258.46356022663 1313.64373941506 1151.95852088622 1168.77561876479 +ENSBTAG00000017759 55.6661931681582 53.4457869865507 63.2326316589409 61.8193964410471 +SAFB 45.8039633803415 45.3019156452053 50.1069523392496 48.0850156088276 +RANGAP1 8.47630533949733 6.85706641241272 5.69781873761296 5.73970813448496 +EMC10 60.1278692861128 56.926933485549 57.8798737781184 57.3271787808046 +ENSBTAG00000013274 19.5577682790022 16.9625179359788 12.7198905649467 10.4707601038537 +QTRT1 14.7111239310352 14.0623312027342 13.9809446846452 11.9211751560379 +CGN1 59.8959820340656 64.8505768837625 822.322562118294 814.892549682636 +DOHH 6.49865874360731 9.12568204760417 7.37033808166123 7.1466716138784 +OTUD6B 25.5165256032837 30.0592819881018 28.1318873305827 31.2690562887288 +FBXL8 1.57021064865016 1.72548196579781 0.772943404124361 1.00938841846148 +H2AFV 71.2491063702323 68.9436134699632 46.5512294427361 44.9079097628623 +SNRNP200 19.4738627410618 18.9230359362622 22.7970497340846 22.3956303725583 +H2AFY 33.7973049322195 31.7343547421404 33.2109419607054 32.5094461572555 +ZADH2 97.1399818519836 92.8115010239574 103.452702803166 104.739677527632 +NIPSNAP3A 14.5095664261366 17.844026209425 17.4090718175393 21.110845621011 +DDX5 150.53508073967 157.261412029361 161.741313880937 158.718460479188 +C2H2orf72 58.4378866706282 58.0465878006198 72.7303669707528 65.9082313611542 +SERPING1 2276.45172636688 2214.28451466993 2334.93653037392 2360.72775043987 +DDX1 33.6508739371051 34.1300063088136 33.6863330745163 37.5534664947234 +ENSBTAG00000025929 35.507971772993 39.4190065532083 36.1344360082726 36.4983139156419 +UPF1 19.9703314868369 19.5655384471988 21.3143304264167 21.3557673190804 +H2AFJ 93.8221664693598 86.4614150597589 66.4626359742784 59.183258953057 +NIT2 35.6374840535149 38.6378672094194 40.8610685288077 44.3824540378467 +NIT1 39.7218110555908 37.7353527235568 24.1427126852696 25.2951406795984 +ENSBTAG00000031788 4.65435107074956 2.89389650819564 17.6779738410606 17.8883697315023 +TYSND1 13.6877488720825 10.1822307301862 11.5094129970269 11.0625918687686 +ENSBTAG00000031785 17.8646144655059 18.7189837614614 14.3794513437632 14.6523784856856 +NFKBIA 31.8211500737653 29.4691586042785 44.8277251117133 43.9278566081369 +CLTA 104.042237609863 96.535855906566 111.719263521584 118.989426414204 +PPP1R21 3.78209777028062 4.92718293516536 5.34622286995244 5.67632977680842 +CLTC 59.4774548523343 64.088583334139 69.315343705365 70.7135727882897 +CLTB 42.7694092140025 31.2259885301891 23.9498685123986 29.2311307892676 +ENSBTAG00000047121 15.6372002237913 13.9554426669834 7.55498842498236 6.32019396160384 +MMS19 6.74148090551658 7.26789540052148 7.45646382120185 8.55273149071924 +RMDN3 35.4228804299488 34.0565464360632 25.6103035882313 24.5422029560503 +SFN -0.0963349494882589 0.708094506695131 0.0150851447237865 0.512991546470017 +CRYZ 191.72642283072 208.495239590713 210.1420962902 222.558729204986 +HARS 23.4144040014137 24.9125621123514 21.0163686881168 21.894735822337 +UBE3A 17.4150378297982 17.8684495731657 19.5032409167397 19.8634013875112 +IBA57 18.0521816716128 10.6635899583737 13.0770571008646 13.6886449891804 +UBXN4 63.9340219455416 64.8073921387844 59.3118635198746 58.4496871233339 +MYD88 16.1019936805274 13.298477402365 16.4851614013262 16.5902587375968 +ENSBTAG00000039237 33.962678507336 30.2999325371126 13.6803792151597 20.4923968436393 +MPDZ 21.5550659088513 24.3460489423034 27.7693560448046 29.7726228860686 +TOP2A 17.6398484647668 17.7284884194965 7.6401199915487 7.62634998422592 +NACA 216.758826345751 225.873377986558 219.668502043375 221.928325268381 +FAF1 27.5457477182602 28.7255609327267 28.4339068862941 29.2393495955795 +PGM5 3.14055159468528 3.88513549808029 3.78555928709256 4.54358626707121 +FAF2 13.3631235626173 18.1826012160272 15.3864303053348 16.0232973658267 +PGM1 106.83810504441 104.178556533575 139.285078358258 144.601751869936 +PGM2 91.7832879201739 98.0064269425717 145.61055316558 140.68298638189 +PGM3 5.36581829040781 5.73894902071761 6.22623280659722 4.71028336661263 +MIA3 31.4081906119669 32.9233341582063 26.2559574851452 27.5581911590976 +SART3 13.5947943169208 15.4777337017369 12.7347952360775 12.1718984318032 +SART1 10.6104099874089 10.3541523040046 9.14329630852987 9.38871395151218 +VPS41 15.7221967265523 17.3578157592108 25.9025727354923 25.7578205696069 +SLC25A42 40.4956391966204 33.7013320146768 26.2217374913245 28.1032983682868 +BCAM 73.9602492862762 68.4832393914644 56.0298387242394 55.4885235698296 +SEC23B 18.4204844663377 16.733244357285 15.6486816376737 15.1741377945215 +GLOD4 67.7350388070704 65.3898284071843 82.0273881353335 75.8950309020101 +GCH1 28.7442316845179 26.6260788796454 23.7634372647621 26.4101999445856 +ENSBTAG00000004632 32.6137859075936 29.3241004390034 23.1434789089707 22.6222072476627 +DBT 47.7341195182196 48.774786005712 58.3875947324081 60.3747146600391 +ECI2 214.054684068514 191.153260195821 205.689891380882 200.799103048577 +ECI1 249.711998507453 246.378204970446 277.28002143386 267.783946535384 +HTT 8.21557440157481 8.17671823043362 7.5411152875953 7.43799013037993 +NUP155 6.27149394128322 7.68145339800434 7.96923278536158 8.84437907267453 +IPO7 26.3553887632009 26.8123921625124 32.4000009340567 31.4253653937539 +IPO4 6.07273134195166 3.74646251576061 4.23242549148284 3.45091396440679 +IPO5 66.1701618388335 68.9249532438128 88.888525220087 91.5477553886893 +ACTR3 49.3235903755028 52.9464264676339 65.0015511619401 62.1023252326438 +ACTR2 52.962946845363 53.592566504524 70.3580399484652 75.9645372743112 +NRBP1 34.588575115151 34.0729560130648 37.0425586245903 35.2728160636513 +VPS11 12.0156919785196 12.321758368833 13.6931354239811 12.5067496194385 +ENSBTAG00000047815 1914.89456712222 1826.52893508468 2698.8804439788 2663.4886871732 +SDCBP 117.011131773351 118.164693966374 95.3771238570286 97.1388018104789 +CARS2 35.4496472592801 38.8250862497742 29.1529652470442 29.9475918803669 +CASK 4.3474459788588 4.55134344894944 3.82122554953055 4.55967928711654 +ENSBTAG00000009029 23.6233642958436 18.4564215854565 20.4833926025748 18.3139508200565 +RAB8B 7.45007197079153 8.40200170768099 11.2176911552558 11.3406984880565 +TNPO3 13.966668431471 13.0160863235972 9.9637921672025 10.7686336104246 +RAB8A 39.510212707651 36.5908055694139 29.1569942481081 31.1169845669939 +NAA25 6.23487817285695 6.36728448050951 6.20518990908178 6.15250777176107 +ENSBTAG00000032899 86.049166873706 67.5311644963553 62.3016390245488 69.7285228189408 +POLDIP2 95.8293803680038 94.3638421154156 96.7891518667553 96.5475650827064 +MARS2 3.73243645211188 3.96912529990429 3.82016258981908 3.93912551946043 +SCPEP1 77.6735604769274 78.028657653609 123.100914675852 121.974918846306 +MAPK3 15.2601694058016 14.6775235091189 10.1899148572533 10.6224117238592 +MAPK1 33.2305991366516 30.8778082388604 39.5644027700186 37.2658147308851 +ALDH18A1 18.7105816416791 20.6396121565089 11.8149376717101 11.1474910428878 +DUSP3 11.6496074943803 12.2441487374417 13.9359790110954 14.8470649151555 +SHPK 18.0821238851871 17.86672233679 23.5248615698827 23.3618464185427 +DAZAP1 37.8799959922539 35.1017600879671 29.7070405517912 29.7533586095969 +PHYHD1 43.7640725851585 37.9154305729229 55.4423437539559 51.8159793147709 +COPS6 58.5072403458031 69.899403876857 63.3172580003413 57.1996572980885 +RDX 52.6114337651328 52.6383755468234 54.197390700969 55.1147680352122 +FERMT2 33.6563829957111 34.3396695730615 33.0263000103357 35.4440989781716 +COPS4 21.9027116951481 26.0631455003078 24.7749027495421 25.4020728201235 +GGCT 14.1354791001096 13.7306956035679 9.37381109444689 9.72912619972028 +VKORC1 244.598024152129 260.708785290349 322.425876764236 314.772096966896 +BCAP31 205.576206057289 203.797581185292 184.744358268161 182.189194472508 +VPS35 28.3515055144866 30.0703266555904 35.5157165214611 34.1579707262157 +WDR91 12.0015961797457 12.1753528734745 13.7798343105851 12.4640100528449 +GLB1 24.1186771013819 21.4963637300747 25.4394109602212 25.0123146402644 +DECR2 234.498467252074 218.584994292019 216.701219333293 218.137855982775 +STAT5B 13.400427909547 11.5227065237043 17.2319743558418 16.6496102976457 +DGUOK 23.5663100186018 26.7228852019182 26.322864904498 26.6542216911251 +CSE1L 19.0651511666332 18.9337096350393 19.1241954346929 18.48653575763 +XYLB 55.5269378923534 53.1366763951751 81.6654146460998 80.9069213191195 +TBC1D17 13.6058512642526 12.7791142260874 11.3584127022527 10.913843300906 +FBL 23.8832355116646 22.3803330562889 19.2812957474872 18.0673032216579 +RPL35 424.031485648653 393.001117108773 360.099003700202 364.4762514406 +NUMA1 23.0880065188302 19.5328025194935 21.6247122004114 21.6364161871588 +PMVK 46.0953044695285 47.3419722831166 45.1591379970778 45.3221105710339 +DHX30 9.24769956280675 8.93721297521457 9.83587875804571 8.70152254996966 +HSPA1A 269.787667094603 251.62731274422 151.967281979127 151.411924088173 +ACAD10 26.7656413487035 27.1422180359745 48.6043692940848 47.0952799880001 +ACAD11 53.9998408989374 51.7309397173514 70.5512088842909 66.4501527074877 +CARNS1 15.6302265518341 16.0248747143022 11.3198373520649 10.7329281750751 +HSPA1L 0.745640524782395 0.909313549921272 0.583470486473317 0.708626880529932 +IDH3A 7.98267611204176 8.59905183254676 6.26930684691533 6.10716478232173 +IDH3B 73.5787024764148 76.6955142250045 67.9649117515735 67.9225303369715 +HCFC1 9.71268088516249 7.96676510401859 8.41291714497422 8.18721694125244 +HAGH 320.7643502379 312.845433510488 369.020940733264 356.313873331614 +PLOD3 58.4839679218677 56.0555857844664 39.7814005583258 36.0023821210492 +CPNE1 12.6584851433062 15.3308487269693 16.9940715379856 18.0956854823587 +PLOD1 25.4993363509329 22.7168297072226 27.9973099100409 26.898082884018 +NRAS 21.062305878805 21.8364993205667 22.4184696010274 23.8798120231592 +DNASE2 23.0060626572951 17.9502746169507 18.7487874682989 19.9613073636686 +FOXRED1 247.949400068112 230.423744158118 241.680842707501 245.408309677521 +PXN 17.9686453778687 17.4658525963449 14.9077565941345 16.038192587493 +G3BP1 42.3631049415128 38.9104119829863 42.4684767499064 42.7866899931716 +ATP5ME 353.469370628812 355.115755786409 265.308687030963 287.535871367604 +UFL1 11.0830041419632 14.3944034345299 18.7493671424354 19.1103876787092 +RAD21 45.1066142155301 47.0146701935376 37.5060685919954 38.9470121282241 +USP13 0.275238628793402 0.597230149983868 0.832887629950203 1.13256037078046 +ALDH6A1 229.868536315757 237.42997240001 327.836632218327 325.082053837238 +USP15 14.7313553673598 15.9566693668984 17.3948503622875 17.3400488070756 +SNRPB 56.1619731611772 52.1524904081311 39.6830594154143 39.8775323923097 +SNRPA 15.7769976314685 15.91336966994 16.152232120541 15.204107592499 +INPP1 14.5153103253809 15.1938151008945 14.5161673833787 15.1090825629054 +SMU1 29.6912275425723 27.7397382417829 31.5369443617382 35.219155278466 +AKR1D1 272.776873701169 286.136890053903 396.580420859608 384.327656269065 +TXNDC12 59.8893200171482 64.8618765837679 63.898332782617 64.1876815429761 +LYZ1 -0.0791865853159649 0.131950374533308 0.171057817999771 0.00933507405476486 +ALOX15B 5.90597239295678 6.64600921505115 8.91429322014961 10.4894722762914 +PUDP 8.20294617120969 6.92291387945383 5.91452581587276 5.36723363299174 +SCFD1 25.3953776576008 28.7260751714317 26.117264513947 27.7983890947664 +SCFD2 14.8099688276845 15.5152629667191 14.5649305008591 16.6987823344383 +PRKAG1 39.1939294064121 40.4711391343886 25.6325420662137 27.7878243476727 +ENSBTAG00000033457 18.3643717601474 15.9427632893241 17.4396460141839 16.9375190111486 +OXNAD1 8.44374448268986 10.2522524603183 7.07022019916684 8.49731092547635 +OR5C1 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +P4HA1 16.226135794672 16.8902057511662 12.8499006631271 15.1163427356115 +ANP32B 156.413158557593 148.055175300332 197.661655659312 187.283829181702 +ANP32A 43.3393416051972 41.4532019130243 41.9735295808989 39.2689563573176 +FDXR 13.38130604377 11.9678987901052 14.2547230161169 16.070299898422 +TYK2 17.916728597918 18.6132924524872 19.9918698650355 21.1583301189447 +TAT 312.635085955465 322.882100227592 399.850669778947 399.025515351158 +SUPT5H 27.0309880502502 30.4088766967618 24.5851986356352 25.6086039261571 +NAPG 15.8586773767002 15.867244718366 18.6888015046724 17.3810188850619 +NAPA 44.4273080599416 38.4604605383033 37.4563715208489 31.3906094012176 +THY1 2.06688196006302 2.65307666238319 0.238813469976397 0.25559446030567 +MRPL58 38.1602957762955 35.6843938429714 33.9022095506651 33.0755835333021 +CDC42BPA 5.20061572065387 5.65462185434249 5.85087253904838 6.47418625939765 +LARP1 30.2230349543118 26.4890485792889 29.496503224176 30.6023512171672 +SF3A3 13.2814819874267 19.5421581404608 19.9684501511313 18.4348438263926 +SCCPDH 75.1189543171997 88.4702602383857 104.995829525089 103.943472925424 +FXR1 35.7963199133122 36.1702086397207 34.9800897733499 33.5203413906148 +FXR2 17.7997161488082 16.3221969985267 15.6028274030886 14.9018798301877 +AGXT2 76.3330682487137 67.0619586697834 128.406507266834 122.84393586023 +TNS1 8.05464576772701 7.34207938928769 8.52471448341095 7.79937443643016 +CNDP2 168.943055039002 155.712548305087 128.142519589125 137.693124447983 +ISOC2 279.120450643257 244.819753076326 212.067367063981 197.989625291036 +NPL 4.26733602150732 6.64288844308209 7.93848833288657 7.81428954774587 +D2HGDH 17.1330069309869 15.3412170538919 14.1927388748035 16.2787944173193 +PTER 1.52660879490687 2.66229430670648 2.0456570213599 1.598227726124 +MITD1 11.6730269692544 8.40382298929611 16.1245519550127 15.8409541322142 +LDAH 18.1327944329541 21.2154592226544 23.808010911847 24.8200690652319 +GADD45GIP1 28.8741525319805 22.9320060211582 15.5733162001729 20.3664346068878 +ANGPTL2 7.02581160916126 8.08212901025634 9.59813641412471 10.7519962738355 +ENSBTAG00000045947 228.874846534089 164.472204363617 178.679685533762 172.451894588149 +ACE2 21.1633297909585 22.1612401771336 42.3245830087515 40.1504095905197 +ENSBTAG00000038755 0.890303810104046 1.48680811674711 2.10337376667357 1.77907546013779 +TSN 20.6237145934396 25.0770096123819 24.7835516598695 29.0436672573912 +PBDC1 15.0052110785941 15.6204680330454 21.1493578023958 22.6227184495619 +ELAVL1 19.9766125313715 21.4132969886373 19.4958410221921 19.3860801379889 +ELAVL2 1.26627903567099 1.79934921210608 1.90302572329506 1.52802912033218 +EXOC4 8.85004988583434 8.78706656170444 12.8287961797467 11.0747221920717 +PDS5A 11.7532103657767 12.5475050899883 12.5414327908691 14.0748980872679 +PDS5B 3.83826837028904 3.99934301025724 4.65470665025829 5.17639254366795 +MYO18A 22.1197965105939 21.0519495142151 25.0360417343663 24.9129454933122 +GPLD1 42.4981699578478 42.8085074978598 76.4602634091007 82.1480124253853 +TST 691.816469841369 665.802393734005 494.821134446626 496.283477588978 +MTSS1 53.6475357792436 54.0286549863711 85.7889474042031 82.0165981195736 +HSCB 8.42537635950705 6.45569254675281 8.68938315364616 9.48430784956467 +CHCHD3 26.8844727351995 27.1670813272387 22.0879108968381 24.1309085100989 +RPL7A 716.562454728101 693.239868197911 597.993749420658 610.867904961583 +ENSBTAG00000013919 162.06680236321 163.391124435519 281.303999495638 298.28504384042 +FARSA 15.5269383561278 12.2265621784344 9.79438138150653 9.18017010477135 +FAM151B 6.86630748723827 8.7671083295479 8.67164073476318 9.65006507068972 +PAICS 42.5384267883883 48.9751636315352 43.3122102310231 43.7263975470076 +OVCA2 12.0489171296806 11.7804471307654 13.6971254298013 11.9467754976929 +KYAT3 30.7759316490574 34.4595698519317 40.1962011289136 37.5883858923874 +VTA1 14.9000730407052 17.0127105476118 17.0477105279358 19.3219060632302 +NUDT2 12.178668724112 13.1648781700133 11.2819435629191 10.286010225291 +KIF1BP 9.8947853187642 8.34490925065103 9.36703047297306 10.5904844577957 +DLG1 14.0445877897505 12.5653575824165 18.7782275560994 20.2868254682669 +NUDT3 20.0236992850512 20.4422450970993 24.5768516283314 26.1690876521419 +ENSBTAG00000047973 55.8159204356326 45.2901640729245 45.4459719160515 42.8379446657739 +ALDH8A1 165.737996550188 174.448557611868 214.017679136199 209.699425423819 +PPP1R18 9.210099240885 10.3649660491827 8.51922046034667 7.53416272770807 +BNIP1 6.54708368554672 6.61939776777978 5.87377879303622 6.56224011941991 +XIRP2 -0.0761500202387796 0.148768431771444 -0.00598725580927131 0.00597426351094174 +MBL2 692.454521865675 673.167947103898 781.202585196523 779.593918835038 +GZMA 7.18555342468225 8.19486299609431 8.02515307236541 10.9082435377862 +MTHFD1L 2.15908014528977 2.65677605565207 2.57080785242417 2.24055035645694 +EMC9 25.0342376059896 27.7493877921097 28.0366595116193 24.0360052463318 +EMC8 18.3780098214678 18.1300160681639 16.2542641610091 14.1857744903103 +FBXO30 7.19306378757013 7.33383419681894 8.91175494933049 9.56707139041302 +FLOT1 31.675228847069 27.9016216539107 29.8822590628392 32.7028641474601 +FLOT2 61.2135185794843 59.6123369633461 61.1174174960802 53.55706985902 +EMC2 49.5931131643632 54.5980341810805 52.7020579481873 50.3892871822289 +EMC1 16.0180607575666 16.2103847127139 15.771427872736 15.5986589193972 +CNRIP1 5.54807426390459 6.11431408850286 6.43977886374382 7.57326683618093 +EMC7 77.969064124163 71.395856349921 86.0272111680281 82.1694532245806 +MYH10 10.0424972480164 11.0336112245796 11.9582033677161 11.3377931990329 +MYH11 9.54526719697538 7.97567792321246 12.4759936458325 12.2829979572714 +MYH14 34.314147615669 32.2896025021737 44.9870143628713 43.1291987112099 +GNS 38.237035406298 41.265487694016 65.4294459699096 63.5654185132283 +AP3M2 1.49782630742806 0.634787745255 0.96057261620705 1.3437219776556 +SMG8 3.42942015551812 3.32948325360438 4.09795959293307 4.55673438609611 +HTRA2 16.1158005729517 16.9573470310132 14.9753872310936 14.7072170450256 +RTRAF 144.336433784021 145.395233195248 168.823297201046 166.77200558296 +PIK3AP1 26.6016701370613 26.8706247633894 41.9838810086615 43.6175774808822 +HINT3 15.8364298753516 18.206633671654 22.4491049291387 21.8330314253157 +HMBS 28.632254359892 27.0605874638744 26.9188252336884 26.0717176004218 +SMC3 19.0261605826906 20.8060073984646 22.6410322521543 21.3332705608157 +SMC2 5.22845758071772 6.07343967691474 4.73752304037056 5.14747858170804 +CDC37 64.3929065579936 61.913064486355 74.0834418372789 70.7212997265451 +ALAS1 115.151311365731 117.564034533738 188.101611007038 184.892687742198 +ENSBTAG00000009788 66.6716065398352 60.2745299885807 60.8189980141157 57.4379773775794 +NMT1 16.6263632182399 19.8180755552473 16.5355619763702 17.8778171373445 +KIAA0513 2.25546082683113 3.40155218045331 1.83057803025047 2.18875890786124 +CPOX 43.7262357492148 47.9594285073224 55.8309454370466 54.8475316136716 +GRIPAP1 13.5672267054925 13.8275267856184 13.2981545786103 12.0738173148676 +TNKS1BP1 23.7226340255756 19.7916498294943 19.3870739913957 19.6005624791865 +LTF 10.3084872927472 12.5679847138765 2.30029510717804 2.92694790516449 +HIBCH 45.0253869917549 44.706247216597 63.962113850094 64.2069576428387 +LASP1 51.5960615471965 49.3791038451155 41.6664430364045 40.2693185720373 +AFDN 14.601516193562 14.6907632670863 16.3270983281382 16.807737718302 +PGLS 21.3143763864552 28.4281764687648 17.6100151290137 18.7371659804247 +C8B 584.708425105681 589.934500705681 805.991833122348 800.275215216112 +PPP5C 25.7239620604616 19.5444846670231 18.8173510691401 17.219718214928 +LMOD1 3.89684747844057 2.58521281765856 1.98254722658432 2.20486794867369 +GLS2 90.6882344914224 87.7774139289737 44.3225653611859 42.7323821279058 +MAP7 15.1013959736674 16.4561456062753 16.5496709733891 13.7816709377647 +RBM4 49.6437292819515 48.2618384299899 41.35334339525 41.9300732433284 +GALK2 9.75121408205385 10.800225316101 14.0168225909383 12.3725640922194 +RPL23A 5.45836351912194 17.23416893446 0.689583398455034 11.9182959545004 +SPCS3 47.6611040990013 66.2068179781569 48.5553527980865 43.278804483277 +ARL8B 32.1411742513569 39.6606214713402 39.6217613999586 43.8660224590803 +EGFR 18.2993414471952 18.0597191447969 20.6242005177636 21.2302943791021 +CAT 3043.50616857322 3290.12459735644 4103.40586418831 4069.54420624465 +ACADM 460.844151581568 471.190802190025 554.240560825634 567.411278729941 +WDR82 29.1717843119969 33.0869586713391 27.2258085467776 26.8902209902222 +ENSBTAG00000011511 14.4748992268253 17.2478033894467 16.4148310545917 17.795936033628 +CAD 6.13118779650012 5.92388540082527 5.49075417907794 4.91740602041326 +NUBP2 13.9584158469089 10.0465298220048 7.75053843772039 6.70447457157033 +PGD 27.803762722824 28.9698405619714 19.2165523511764 20.1090946223767 +DYSF 8.05211567286547 7.32127858727145 9.62201999338516 8.43953636020681 +VPS25 85.1639692932175 80.9779055316256 75.2576841878936 78.059880917959 +DYNC1I1 1.12405083373023 1.57811736229263 1.3975737412591 0.833401635473123 +C29H11orf54 98.2518450666073 105.806457287064 139.906489028691 139.969777056134 +VPS28 89.1867140887223 79.6191625413365 87.3319384221159 89.2955925226863 +VPS29 39.1129337506061 52.055587948604 52.0876556424385 50.5797101560396 +NUDC 53.4168915395692 48.511659872358 45.4088477483401 50.2864023470896 +ESYT1 6.56885975463931 5.9794391051439 5.95556644910963 6.21322589929178 +TOP1 17.9413089222926 17.0843333752423 22.8222843602739 22.4716802347571 +PGP 16.3011630943011 13.6197612938371 5.92179130135984 6.80225928241133 +ENSBTAG00000047700 5.63372071555166 6.90791249774946 5.57740321762006 6.45101798641369 +PTPN23 7.59365718306159 6.66732240133969 6.46370644326997 6.38238521705865 +COA7 10.1336219699518 13.6216450242057 9.41704550537074 8.71875783909898 +TMEM214 42.882540023939 37.0858758078196 29.5938399501398 29.6664204724946 +LGALS3BP 259.312287275707 256.189369706832 172.9705660128 179.692502039848 +SEPSECS 31.2598147182094 30.2295989859232 47.9051957464545 44.3013635827781 +PLEKHO2 7.13624183248456 7.83420722644858 11.0851408075128 12.630876034533 +PDE12 4.43438730317842 4.12903803419116 4.11170154395176 3.61524996113017 +EXOC2 9.80001792685146 12.1179731300847 11.8133455818426 10.9569109941749 +ARSB 4.19208066997401 5.26835172101796 6.25634735463443 6.84993212958509 +CA3 200.50286674435 201.529477131609 383.542978272754 372.123286920197 +CA2 4.28857278985168 4.71910519997514 3.34186084477428 4.34343755481715 +EXOC8 2.26233733143659 3.64009551293126 5.25464235132341 3.34250327956854 +HEXB 22.556231193828 21.828233383309 31.8368485939138 33.7851127487918 +RBMX 59.1571359759493 61.0362441362078 73.860422392453 73.1004799975219 +ACBD3 12.0573857089373 12.7488087239471 13.3178402205299 14.5761238746005 +ANK3 23.9246949087038 24.8005618993006 31.085911290525 32.0633167207318 +ACBD5 54.9224167240282 52.4946428066308 71.506654491822 69.8229135924418 +ACBD4 28.6060197073528 24.6880926872964 19.9638067757714 21.0512223773584 +MON2 13.4187592329722 15.0428472956015 17.2981940908923 16.8342317802328 +BZW1 98.4201826611042 101.870279881068 99.4614346589457 102.399670582266 +EEF2 464.873006205065 440.631162659564 522.026595660998 517.930663268099 +BZW2 11.5952412368381 14.3153964746484 8.64683022275341 10.489081301486 +PDGFRB 5.74724391377519 6.00566356213018 5.08742979883997 5.22814266855956 +GSTA4 107.923912074506 103.029470989961 154.743621511414 148.31367620496 +GSTA5 2.58280817622381 2.16879730206223 1.21669786459656 1.22740170771268 +EVA1B 19.563052974285 19.7454383493801 20.758125181339 20.2347994447742 +UFC1 65.0251565954642 59.8574217366757 72.1390318431269 71.1308753247691 +GSTA2 746.165690027507 760.998427529931 893.01019903362 881.497799194092 +GSTA3 2194.26943875842 2151.19929340886 1742.03238343128 1750.81749807887 +CTSB 277.529282895953 262.097250048635 369.477036183516 375.196406008177 +CBR3 4.68174074496991 2.90972335152856 3.80876797581614 3.95200186850223 +ENSBTAG00000012096 141.353130437225 137.392960462823 147.817200093637 150.235882465174 +PYCR3 26.6337799060266 23.4078075450408 20.2782299408329 20.121150107428 +PYCR2 13.8970209089096 13.0619985614703 11.6647567579557 11.3727284403322 +FAM234A 18.1354438980281 17.229181447792 13.4165937373404 14.3952233364429 +RSU1 23.6863625828217 29.3802705384851 29.5815599917143 28.371728190695 +DDX39B 83.5001189404008 87.6720905213936 79.8341536668904 81.1028785059972 +DDX39A 29.9893582363234 26.670285962177 32.5532123589436 31.2519371743461 +ADAMTS9 0.461399489204719 1.03241458394676 1.20274367225382 1.2307546275034 +STRAP 23.3579343570105 24.9639482071855 21.4965142899058 23.1945900449521 +CBFB 9.83904558031536 11.2885129639892 16.0033111666979 12.5999672327801 +ENSBTAG00000014567 29.9455027795893 28.0392974221504 32.8366040630885 32.3253791128518 +DMAC2 21.258374419596 18.8866371616887 16.3079991458764 16.8680807039819 +EEFSEC 8.66630368922915 6.73379875337805 7.80551548916725 8.20124246162128 +CDH2 52.3716337776693 47.871330141565 45.8575352794363 45.0653177186628 +BOLA-DRA 269.746300611459 273.599019304188 449.29074642074 437.240156990022 +ENSBTAG00000022715 194.954587809153 185.128285510435 117.075768166606 117.275128242666 +LIPA 55.9201062998632 54.2755852407464 79.0904828262186 76.8227985915992 +EIF2B5 20.7314187941979 18.7782936948476 17.014598011362 17.4500556673231 +RAB5A 24.326517083206 32.4932060896124 36.1037826604373 36.1072479342914 +RAB5C 66.1240710703252 62.4897608188321 59.4728972964248 60.5602680349971 +RAB5B 34.7153665154458 39.9185065552528 44.6292797682759 43.2545278941998 +SEC24D 34.5627031001292 37.865355101177 22.7576180677007 22.927613269238 +ENSBTAG00000019516 1593.42569168947 1475.40754102913 1064.54557083712 1022.63957911623 +PEX11B 14.3289325296461 12.3172380631616 17.0934113512467 15.3556924761085 +SEC24A 21.1913145513025 22.6411085225091 25.1542308694847 25.4655163909051 +SSH3 13.2399324422478 14.0419298442952 11.6393403208284 11.0694049974257 +SEC24C 44.9473492302388 44.990282878581 44.1869425299255 42.6379136500773 +SEC24B 15.2643910793443 15.9978756759114 15.7842556232459 16.8623553638853 +PAFAH1B3 4.22414995051723 4.75245070298287 3.0568538214363 2.07419913846492 +PAFAH1B2 10.2959121016432 10.5214496934152 12.7203033993658 11.5738716841611 +HOGA1 119.29743718086 105.186383842129 68.0101936801624 69.9896036260331 +PDXDC1 27.8376593718009 27.3256138451865 29.0216207008965 27.8662139613178 +MIF4GD 39.9333339691813 44.5361193722865 49.9681367782293 43.7426922539626 +SCARB1 63.76932559426 63.3647829781403 37.5677711771305 36.4784509732474 +AZU1 -0.168766967791324 0.271787770038126 0.608567783367161 4.25792088067845 +PLEKHA4 7.64457247680194 7.64370592718686 3.26989216334445 4.49751784801494 +PLEKHA6 21.7653603037882 17.7486360365284 22.4102150789175 21.9213998869546 +PLEKHA7 8.64523590333559 6.42725573887565 6.64847222342864 6.14912747381297 +MRPL47 18.3294614105564 19.7708224902998 21.9067408058261 21.5258780897139 +MRPL46 20.0629978400843 19.8013812393094 22.3149920326568 20.5412403279916 +ALAD 476.132408558242 466.601757759162 497.227816637707 496.630111752031 +MRPL44 18.1286589264515 22.0991363543603 20.1565358298267 21.7408767789366 +ACTB 597.023464771475 567.094229726717 508.283639734785 514.451111817721 +DGKQ 17.6276724287978 15.7834617007724 15.07793297539 13.6865736106266 +PPA2 81.3551086745368 95.3945806034225 96.9676839444458 94.3722538928443 +STARD10 108.511232151823 105.842155934883 147.025020002826 151.232387385504 +CPT1A 93.45724518619 91.6018867756667 108.351279152493 118.73078286594 +ERAP1 9.1976970377989 9.65071619739146 12.8121519509035 12.769710890077 +ENSBTAG00000023939 1551.04184545605 1613.20166307851 1568.73058560263 1548.91483462648 +NMRK1 43.4174837843657 47.0209374228533 68.0416833239088 65.6333078832547 +RRAS 16.747358073746 11.2466461750735 8.08080923813226 7.37937857834195 +ARFGAP2 23.9178549853905 21.6018030645818 19.8226327745419 19.2998638852488 +ARFGAP3 107.657693422812 102.924304776232 87.4463397618231 87.5470830332536 +LAMB1 17.8314710998546 17.5071012743703 11.8372887719559 12.4196642006376 +DHX36 11.0812839673695 11.7939233409708 12.4994168075923 12.2445642109765 +COPZ1 42.8643593009195 44.0091262280175 39.037375209072 41.8838925575294 +NEK7 7.00203343128985 4.7401467204656 11.2385201701388 11.678370806126 +DDX58 15.9466038901161 16.1155481779031 16.4913742502218 15.9944332273497 +COPZ2 184.029755042505 176.236640796662 200.100030494792 216.917346104584 +RUVBL1 20.9850902426134 19.7343833271478 18.2222380356119 16.6097693219375 +RUVBL2 10.10349527469 11.7323713197849 8.24964604733889 8.80380226129257 +U2AF1 79.0225596857751 65.9037159399053 59.4520615672312 58.402123021419 +PLA2G12B 68.214827846587 73.8632204821886 79.8439640043979 88.3239149761369 +ADAR 19.9172442585958 19.3360158984386 19.1943577126566 18.2747800617694 +NEK9 18.5121898757576 19.3162063600013 22.1740883811258 23.3054344045816 +GATM 1451.70619846257 1531.12097581928 1688.58615102444 1655.55893450301 +ADAL 5.2949046022207 6.09538183991149 9.70073930745554 8.9506143826316 +SF3A1 19.4064252370544 19.5497371961641 16.299397330698 16.0801201972793 +CDC42BPB 16.2853683607784 15.5625538426832 15.2719614540943 15.3256226927902 +FAM129B 5.5781468477214 5.9319714747475 3.39794433269901 2.99654046915471 +TXNRD1 18.8910911747571 18.9334181531627 19.0201244307085 20.5856277298196 +CAPG 6.1577307043204 5.98868293221782 4.43070791083378 4.07824198209847 +ENSBTAG00000045566 -0.100636525687332 0.481398239656842 0.647550848430002 0.338959446459785 +TPT1 4167.96247295675 4364.17605555881 4214.18264356917 4112.72310414556 +BUB3 41.8148850031452 44.76915695045 34.8090720590334 33.4411922482451 +ALYREF 19.9029461999935 22.1567964703724 16.7983855634929 13.5709073490524 +PEX16 18.9464146158561 22.4602231849199 17.4453639022667 20.3675529020563 +ABCF2 11.0408273926693 13.6730729123146 10.871915799766 9.58307221873345 +BLVRB 235.809716527245 218.009721473805 199.136190755556 195.899646295322 +ADSSL1 10.185433438194 10.0022388734457 10.9262795009281 11.4691439687937 +GLTPD2 55.7732278177319 50.350797477041 32.9372277866993 33.6893327208316 +EGLN1 24.0317041751955 25.003596829216 22.2487521189855 25.7065533315377 +OGT 23.5532056144214 26.0613894691983 31.9383321303467 32.2511078883491 +MTHFD1 249.862799908138 260.387087757432 224.558973225771 224.264397982218 +YBX1 311.150043121433 313.959622514081 312.305636925062 307.799054556906 +IK 42.2600738142463 38.2609890622335 42.7405259082495 44.1305649638424 +C13H20orf194 2.50195381249191 1.95149861802315 3.71553108019402 3.36896055289964 +ANXA1 32.9433357467567 29.8281850816687 34.7200024218719 35.3133513944752 +NSD1 13.1043955777185 12.4053630044316 11.2691244219694 10.6229135614559 +METAP2 21.9610461744528 22.0177768587135 24.5151438714469 25.2903359586766 +ATP6V1D 38.3251155540862 44.7985862559749 41.1273798700801 40.8029512113646 +CCDC47 50.7916568541861 56.904021246753 53.4415432892393 52.3132000934562 +TCERG1 7.61881572932312 7.68093337105659 9.06109832065556 8.71139378455371 +RNPEP 18.1481792369084 21.0975987114168 16.3629904445153 15.9038234844754 +HSD17B11 720.126650663004 789.440442987638 981.093161015549 986.801507993493 +TPM1 39.6149672090899 42.9448532796675 29.4028023266716 35.6713684593632 +ADSL 37.738584722205 34.9224960591259 29.9779822698863 31.1625153379327 +ENSBTAG00000005146 142.632754326678 146.36350247103 160.247022650006 157.495604717641 +AS3MT 53.6342784779255 51.8329833963492 61.716968079246 62.6767207798227 +MYH3 0.377748603289295 0.678412638261083 0.167016951854105 0.179247312640433 +COASY 26.1115750902764 25.6162990148731 19.8600033670184 20.1381501997898 +MYH9 56.5325205021765 55.2021117388132 53.6173954288969 52.9275893726469 +USF3 3.73258083212244 4.09291722782957 5.01318470471699 4.6622913252654 +NAE1 16.2089803119349 16.2200100011975 19.5023977159276 17.6671568461672 +RANBP1 34.9478105337381 30.7441077125288 19.9048830776794 17.8122094279139 +RANBP3 15.5157765218109 13.3259178718281 11.9182400938753 12.7708104941484 +CADM1 53.6167299973857 45.2465665517338 48.9991185414415 49.5320006272506 +GNB4 1.56426562274267 3.0336373622038 4.0624725987958 6.37859433023665 +SIPA1 8.83511772342155 9.6778353921789 7.31700380320934 7.68419426120918 +GNB1 73.4397198734745 70.3356292224685 70.0507048786498 67.9589439408933 +GNB2 70.3880800659396 67.2627624402296 59.8720959242864 63.2790068801495 +NUDT12 26.8662408330596 30.4242546649299 43.4226718059195 42.5232135271289 +GCN1 8.73753388118199 7.72950258318686 7.6061976594968 7.63710516835211 +NUDT16 17.0766779150841 18.7594759136459 19.0253353318258 18.7237807369695 +NUDT14 21.7305887086463 20.7390277926729 15.2712159048222 19.9467849456411 +ZW10 9.8206403550648 13.3008855163681 11.9964348330285 12.3502028172176 +NUDT19 11.0521265686541 11.5266932395112 12.8082184486694 12.0448433295045 +BREH1 107.038062723323 112.515626585482 69.6885628428017 69.0260649626382 +STX8 28.4226310137582 29.6871561499444 32.8579794838751 34.5885170475618 +RTCB 21.0299665327876 19.8857115234504 18.0915988608337 20.9180262980403 +SDS 11.2792048203494 7.3122946532961 16.6575733290508 18.9569459622985 +STX5 13.2432969574451 14.0396132581579 12.6291160118079 10.9687181811043 +STX4 13.5694620350002 17.7268259318808 17.2205629368392 15.7266602257681 +STX7 13.9343203916639 15.2267517326069 16.9085677650935 17.2878124059977 +GDPD1 5.95673864994867 6.30189261901867 10.3220101179838 6.31239063359186 +RPS3A 1102.2138573474 1133.61431452022 1103.12897690816 1088.79025033585 +RANBP2 11.7456222992426 12.8686371729041 16.6092777646507 16.3759819151538 +POLR1E 8.84664490286323 7.40911599682581 9.03184801932564 9.58710484122523 +PON1 722.84121376508 749.240037480132 1527.5722190213 1494.50425695651 +ECE1 50.96192498049 46.6874896393058 46.8543539887573 45.4353390833999 +ENSBTAG00000046839 19.9704379772827 21.6014019152386 10.6758532434096 12.6527109286553 +IQGAP1 14.094713085053 14.0874041278241 16.3284980009982 16.5895609720785 +IQGAP2 108.195955565215 108.112694694243 153.295822286217 150.276759282708 +YWHAZ 35.7513197103977 33.0056378499006 32.4197826656751 30.5027947218532 +DRG2 21.806658222967 20.7792610904073 17.0530723873735 15.0735069531667 +DRG1 14.4278886587384 14.8313920432564 14.6593982701881 12.1017264154863 +XXYLT1 12.1792664513887 8.76798348012679 8.75550663254394 8.3949924571805 +NOP58 25.5404948860646 27.6887492834947 25.536492343637 27.6419811920143 +PITHD1 18.8327590445844 15.8775641040008 19.338822041748 20.4835429906437 +YWHAQ 87.6021627285568 94.2071569428554 80.6424631121312 81.2659790058946 +NOP56 30.3600371136979 35.0522588379546 30.4314793360742 33.2070684770747 +IL18 17.1966230927025 18.9979553961519 25.8126355923144 24.0430395406267 +YWHAH 52.2746631092813 47.6495137316778 34.8644302140325 36.5642746597297 +RPE 49.0172584294339 22.4865179032657 29.336634699936 26.2583046905056 +YWHAB 75.818204664902 79.388536206019 80.0510401163798 81.5455813959536 +AP1B1 29.3651823302642 25.9299380772506 23.4655960585232 24.7502435256201 +YWHAG 48.2432589715145 44.6536912920625 45.3283521704977 43.9719798880936 +YWHAE 153.789670924713 168.554364894442 176.509489027861 169.480312773708 +CARD19 40.5565702088783 34.8010332249099 29.1240315707088 29.7225429316196 +MAT2A 259.609041007302 272.361507409075 188.111519701177 185.28772254327 +ATAD3A 11.7176365023869 11.6624087831022 6.39011377890363 5.95519116665532 +MAT2B 16.106332062348 17.7150574219731 20.9147667728911 20.1786416725368 +ENSBTAG00000045888 101.5360065608 86.9723270194096 112.021157047948 123.203431867392 +C1S 1465.30564548207 1492.8643850453 1544.58076845833 1500.76866824101 +C1R 1674.18532299522 1616.67922409427 1749.46165032558 1725.4701347112 +TUBA4A 24.2064087946824 21.348041776019 9.37022814075834 11.2092012094228 +CALD1 143.159142736314 144.079409368674 160.587392277131 157.939496406888 +TBKBP1 6.07981493775676 4.866658506718 4.15698467038144 4.87967011842902 +PANK4 5.28010423675179 5.64529285493253 5.25853139771096 5.15330553892368 +COQ6 24.7670319181669 23.2394692002396 25.2508595539399 24.3768253463715 +NUDT13 26.2586693290747 24.701318941922 19.6889881224672 19.2479619762367 +ENSBTAG00000037775 56.5866034455041 60.777939340137 30.8366605500124 33.3381065888778 +ABI1 9.85873244413817 9.155815643071 12.1372287025666 10.5272491250953 +ROCK1 24.6046285531245 27.8511957456694 24.0942721601134 22.5382655302225 +ROCK2 6.33575876567178 8.59683457797186 6.85607059922114 7.35762198336447 +CUL4A 40.7600937635882 39.6779456699511 38.0356104527654 37.7401695193642 +CYP2C19 251.640550336004 264.912902809589 910.867404310532 905.853677592549 +ILF3 13.3286416200016 11.7178025790517 13.272152098537 13.9820611407458 +TGFBI 16.0231514413726 17.3484949740316 22.6544884603896 19.6595792172507 +ENSBTAG00000036298 30.0064153881646 30.2550705738295 30.5395600233094 31.8269187105473 +ILF2 32.9398079127156 38.2943271539656 32.406888411994 33.4427207305576 +IMMT 29.7583495004426 28.6764248242735 24.5600131446648 22.4213239534422 +ACADVL 499.834325892169 483.136365885181 268.275497078815 270.024973639581 +NDUFB9 61.3398961507635 61.9887837166286 52.4649489299104 50.6983993118949 +RAB4A 38.6818005374118 31.396877126783 35.8170975355001 32.7533895916115 +PCCB 103.056891134536 103.58679430511 152.562737125279 148.884885545609 +PCCA 101.403807291895 100.248215775016 107.728706222255 106.114594680476 +FCHO2 15.0094615815073 14.1160220365189 21.5460012244107 21.5663959158532 +URAD 181.437928396917 168.795654013073 113.543661019836 119.653799483808 +FAM213B 57.1964031603454 45.4155298123075 43.0105291215037 41.8914730834738 +PECAM1 18.2109359310846 17.901841389797 17.0119399511446 17.9143103914047 +SUGT1 22.4199411997145 19.3469351080393 19.4072984551161 17.8747817824602 +TPD52 37.4535569935823 41.0490113542293 45.6669922069146 50.3771529613047 +UHRF1 6.13782741005227 6.15997491151925 2.960613703176 2.97079547809642 +ENSBTAG00000045976 125.928492093844 133.810301642365 119.475404045969 113.570037052155 +CLN5 61.2711874947036 71.344534239867 94.058059640302 97.8287476178275 +ZC3HAV1 16.6000391514384 17.2762857621998 26.495240811036 25.704275157306 +CLINT1 57.3729468350151 57.3099971045518 54.6012197494238 55.0691292896223 +ANKRD44 3.83124036886285 3.98688165823551 5.19289922531702 4.87964880913485 +ANKRD46 12.2080456838422 14.0760922388937 16.2915087603436 17.2538621640987 +CXADR 17.7848467863998 20.6446561438112 21.9137482038652 20.3391751118881 +CRYL1 50.4356628136954 46.1901739273595 45.8089250267373 44.7852197684208 +WNK1 13.0549345725011 12.2870040300054 16.2717927559205 17.5818930977723 +ACSM2B 379.700701873801 379.91791697982 493.730228441923 492.952449046954 +ACOT8 54.5629104279831 45.1588128045967 33.4055343247354 31.3126660972256 +ACOT4 15.2882252443574 14.6391614335321 15.1750416398358 17.3876558374735 +ACOT2 12.9022268293266 13.3530953148082 14.7480935949725 15.0572695933055 +SHMT2 81.5831103595995 84.3367990513396 51.1548586279581 53.4594316132415 +SHMT1 499.892552012384 466.070171884811 457.567906212046 465.517094467215 +ENSBTAG00000026758 32.0129132061911 25.0126466018106 26.4189333229507 26.6421928276723 +TOR1AIP1 17.8454934056741 14.5764865804986 30.6593348641338 29.2373457516012 +PLD2 5.52476393781964 6.319230931883 3.91391852717314 4.01219090034932 +PLD3 49.3112855988844 46.398204302993 40.9724962684793 42.4737105476049 +LIMA1 10.4879621734404 12.5857429358066 13.3185905714769 13.4539837845945 +KIF27 0.958625116108231 1.46584741856612 1.14935258311329 1.43522865951815 +PPFIBP2 12.4478078993624 11.7623430296473 14.5588191029214 13.2109471019818 +ETNPPL 36.1217442411747 37.6297500537244 64.9205850603537 59.059968256713 +PNPO 29.4450150585223 36.3621405825968 54.2518006782147 48.7233652690943 +ZBTB20 1.0741269010279 1.10489439632338 1.82835134674583 2.43337829574747 +SRSF3 82.1195532145628 93.6157354569517 102.403336521822 111.954246576419 +STX2 17.3370182368451 24.3975092178476 35.2124054880508 30.2262036628323 +DDI2 27.8754994082985 26.8854118893385 34.1378577699646 37.7959478052815 +IRGQ 2.13971341675044 1.9874238194671 1.76791871541826 1.57975113494392 +HRAS 57.0000873796712 119.311174266392 99.0776768101059 67.1844131314663 +CC2D1A 12.5332425114758 10.3653144339098 7.4613094941218 8.59039811696047 +SEPT8 7.23317808184199 6.79303605369923 6.94181394364397 7.61625766514621 +SEPT7 55.785472803575 59.2791402435722 68.6637177702567 66.388434610262 +SEPT6 3.8816159463909 3.47312890504789 5.04464534110768 4.24266155209036 +PITPNA 18.5629245595785 17.0333919660458 15.3707281154023 17.0376937853597 +SEPT2 55.138458499998 50.1155620143685 61.9264659527804 57.8436724894304 +HSPH1 10.9070154824509 12.8044295140681 10.5829964799565 9.83877250596654 +MFF 76.1423456802817 74.0735513789318 64.1125847320973 57.8429027117005 +ENSBTAG00000006819 114.72770109981 115.227908124335 144.78330705169 144.67701559681 +GK5 211.423087900709 217.687281761935 192.269483782548 186.015083268121 +MFN1 25.6693837247363 28.1908644486733 34.8524051448348 33.8112401943172 +NARS 65.0910923751265 61.8139487472203 62.1653995865162 61.2885041384407 +JUP 15.9989934687477 12.0796293556165 16.4918452596892 18.4870335557856 +YARS 25.6652458190392 26.3529118889239 26.4465266057152 25.6403798753906 +RBM39 82.9133962295662 81.8192729094509 98.9548295621155 102.758446797963 +AGPS 14.5110230412325 16.404766627175 16.831953232856 17.1587381376166 +FAM98B 12.1144167864278 11.2281358089138 13.2159799899944 13.040058947016 +TFR2 70.5774289549649 65.0979164814302 75.5982365919779 73.0858340924811 +PARP9 11.122586010732 15.6768301682487 15.52767752725 11.6208435567228 +ENSBTAG00000039643 607.588623596141 645.053482300114 639.45162333932 650.343886885262 +SEC13 43.1461076676243 34.1737248360144 32.7079337340619 32.4014164947019 +EPN1 65.125578009105 64.3370801738586 47.2625855559386 50.2700338040036 +PARP1 21.3481467390293 20.4241246965649 24.2881271441509 24.0968102021456 +EPN3 0.680695611362103 0.915719765958501 0.538524748572583 0.657401345415665 +DDT 456.140859335508 461.076431482139 405.842447579189 390.619258078315 +MPP1 56.1575732443173 53.7773195522338 65.6345620265985 67.6262565752931 +GIMAP8 52.418621261932 53.5244731580421 71.4533196205006 72.8217369076633 +GIMAP4 163.902925354278 168.039801817497 224.586579564619 220.650844298731 +GIMAP5 10.8084860752459 14.1655143924013 15.3592837801596 17.590673367266 +GIMAP7 34.1417077540259 36.2692955857571 55.3327157597768 54.9171481987596 +GPHN 12.4854530498343 16.9456536003351 15.3482134939232 14.8134055966408 +LMNB2 9.80591161629618 10.5376288141908 5.9340962168183 6.14977561656177 +ENSBTAG00000010033 18.5048225333198 23.8293074774158 26.5203258090674 25.4809726398062 +ALDH4A1 188.764128310987 181.584121100204 133.63064647398 133.58536307802 +GSTT2 154.530175778565 137.774162961773 97.4911934420664 98.1815662569734 +TOLLIP 63.3779746794835 55.1006853087437 46.579907518088 45.1233813394448 +MRPS26 39.5272673178502 38.4483629119456 29.5747001896468 35.6317774339382 +WARS 14.6751388423804 17.0370705187884 22.5425859750506 20.2102265355975 +MRPS25 29.7546221628323 23.9383836107144 24.1949673899487 19.0223732526572 +MRPS22 24.786736836429 24.6735752844437 23.8307250914322 20.6999627371634 +MRPS23 83.3850122660442 75.4382114559938 76.5610296579299 74.5611235724088 +LAMTOR1 35.0355120509502 36.8403600157567 38.0416189906403 41.7588875256681 +LCMT1 18.5278231988461 19.9963998497432 25.8536833206248 24.4957414935736 +RASIP1 6.79255980027564 6.87837005557046 4.97674559956816 4.85387096865022 +EARS2 0.971824474837355 1.57246484781682 2.27138088185709 2.00642086729512 +ACTC1 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +NAMPT 38.9589035095105 40.6541827038555 50.8852874879381 48.7885576753385 +ENSBTAG00000016032 31.2444465380257 35.8225260337061 50.0791569567943 46.7631583278899 +CTNND1 27.8174111805192 25.4189638501312 25.2318638913447 25.7602638074172 +GAREM1 5.22199228605201 5.4510134708088 5.07878651936323 4.03796223722093 +SH3GL1 23.3422689331258 21.5583363400783 14.4490415710475 16.0602045999279 +A2M 157.958754224679 161.866071725067 342.903703376926 338.436076079355 +OPTN 66.7039529250351 73.9532103765072 51.4290251578203 51.8825380573127 +BHMT 755.459028063828 762.088905266398 485.905844829927 490.335617971772 +THOP1 85.483907005801 79.1738854028349 105.177269723523 100.760817128123 +GOLGA2 15.3003897967169 13.8613345376293 15.0628470696857 14.3812467148659 +TTC24 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +FTL 4700.5375644698 4672.76061765461 4015.72534841193 3965.60362753349 +VARS2 5.5028278873002 7.12317835198444 4.55554038456043 4.92849262721275 +FHL1 4.31513962277386 4.96225267628503 1.75778521280258 1.77499844153788 +DCXR 300.055572439801 305.504028399992 265.759837958271 257.939262985731 +FTH1 2640.39841870471 2507.39669726747 3492.96774687286 3453.91687615061 +UGGT2 0.0498156499183176 0.253699590689055 0.203844394056743 0.242667698355064 +UGGT1 12.737230703257 12.8531792017474 15.803340262683 15.4492456548219 +RPS25 1262.26949165852 1297.5898683836 1253.54623373784 1227.30818522197 +APPL2 18.8551603324056 18.4594051613982 23.7146040847652 23.4646589823115 +ALDH7A1 53.0222837285836 50.6601879329357 61.8291588180666 59.3779554804581 +TOMM70 34.1711637691063 36.9920653244559 40.186834921149 43.6545574467661 +MEMO1 18.9079198181827 24.1440961995689 28.3763486785549 24.1338529488712 +NT5DC1 35.6134514901466 38.0223576878052 32.9657671254383 35.9204601974167 +PPIF 97.7068337839493 89.1364178211414 113.612052135248 125.348787526871 +PPIE 6.25929821131159 5.31403458478402 6.58224400333557 6.07569629604576 +PPID 35.1210950899941 28.2607017941829 32.5234580812798 31.7466853089409 +SIGMAR1 77.6520527205585 76.6092865671267 38.5977533253211 42.8456485156958 +PPIA 1034.35019844318 1020.13434868876 772.515482349054 751.145693114705 +SARS2 11.0916480960254 10.1542241810923 9.1588015156475 8.78322244764339 +SIRT3 22.7674286556364 18.8961932997058 27.7276111237912 27.3390030133762 +CYFIP1 24.5200446139301 22.1631199917117 29.6515214186433 28.4842227438395 +SNTB1 59.5404491323339 51.5312835067093 53.2925441809757 51.6032913842737 +HYI 40.2585599045089 33.2577691166209 50.4552498225121 46.3187319217738 +AIMP2 13.501989372869 13.0711861031751 10.1455379093704 11.6298317970372 +KIAA0408 0.265486069753887 0.241814480262823 0.455131303501472 0.19204910332876 +AIMP1 37.1971494618183 39.8419793191808 43.6164207792951 42.4922174549254 +CORO1B 42.558050898828 39.6751337369581 33.1869194532228 33.4859668310759 +CORO1C 25.2422522369417 26.6684375155322 19.7530171077342 18.9690651402694 +CORO1A 17.7215135762406 14.4539449859356 23.1897048067267 22.348632948456 +ZBTB8OS 32.3762631477558 47.9720890550815 42.1564576982225 38.5151665343183 +MDH2 221.170772581968 230.79241300938 162.314805032393 166.060620496365 +MDH1 112.107013928413 116.459303263565 69.3533046399373 69.2391687438853 +MOXD1 76.4649234720073 72.0721712445999 102.374107442164 98.3444023563963 +DDX3X 73.9263403987162 71.6539543506195 91.8204247450065 89.7690814721301 +TTPAL 4.1898077270929 4.02096272999204 5.34221934771448 5.93404543161027 +DCPS 3.48004029602297 3.97528538819521 3.24305467732726 3.44679457011092 +THUMPD3 23.7645238346924 24.2273848504228 23.4233110605197 21.9419957630896 +KYNU 40.460266630843 43.3559778114317 67.4912355059149 68.5188669824548 +LHPP 49.5384774706164 43.6060232463584 54.177050070137 48.9653163756007 +UVRAG 7.10645035697105 7.83621349044726 8.54626392671575 7.98419962513033 +SMARCA5 23.2521482729566 23.4351497927815 30.8226224950681 29.719787877834 +FAH 262.588648852183 254.328408913691 332.60223579053 322.934341527019 +COPG2 3.6941803903453 4.89291097917079 6.56985842847109 6.41259856176545 +HNRNPA2B1 350.441670238391 379.307631535797 344.743800118154 339.154002032841 +COPG1 53.2807286570002 49.7338941279748 45.838441949253 43.3969123831918 +CYP4A22 2.46753530422916 2.07474869786093 2.60767796403849 1.75003352368046 +NBAS 5.41598821324479 4.97331838195157 4.68955496059768 5.305396956002 +PDZK1 132.835872270642 142.378934621004 143.05088005242 144.255752391207 +RENBP 20.1291969648876 19.9718651384863 19.9883891991432 15.1708745899588 +ENSBTAG00000001851 4.96888983574246 3.92919420355106 12.5421033267194 11.9316246842058 +SORT1 25.5364273355186 22.1845796919739 28.5714491744467 27.6972654158288 +GTPBP1 13.0583846982455 12.0103235771002 9.72315354395715 9.78182285418381 +NIF3L1 17.1351945260441 19.3420861315404 21.8143344631773 21.5899098913782 +GTPBP3 8.78793542825082 9.81751826284006 8.99460008887479 7.18157632632933 +GTPBP2 7.71415311926382 6.88755073988943 4.37972235698723 5.06136072599241 +HELLS 3.07584724189016 3.38195802124624 2.98131060368764 3.07404164111412 +CASP6 30.103493119971 25.0565260097277 39.0410858686213 40.9377075861795 +UPP2 75.4060996877082 82.0654953624369 111.966040790801 115.545280159526 +SNRNP40 13.0399665224397 12.6968421234781 12.2138786617923 13.4498183133513 +BPNT1 20.0910266148906 19.9066516511147 20.7471005387983 22.3814306892582 +SHTN1 21.5464549400895 22.3440754973299 27.6059257546359 28.3254405724441 +ENSBTAG00000031738 0.734573971264471 0.117437725779074 0.0100543503631274 0.0229810596966554 +CASP8 10.658798438012 12.6455137866218 16.3874406215285 15.429300326113 +PURB 5.75048191983693 2.33572988678973 6.04701346675588 5.52013714925041 +PURA 3.65174795764468 7.70207283455392 7.67111405081849 5.74723893972894 +CFDP2 40.1525945258458 45.311133940249 44.8061005638147 45.6548763883384 +EIF4A2 188.050223012901 209.774181287971 294.522804066963 295.815543757548 +PICALM 147.16771180242 150.396521745931 162.835437194455 164.723045292576 +HECTD3 14.3189924343358 12.4683965744063 12.2809208337099 12.2938148883325 +HECTD1 26.372651217564 26.3468331929756 26.5393070552693 26.6330830760713 +ADPRHL2 9.39752883549689 8.8303290686298 7.07432691653351 6.04042756161582 +MAN2B1 72.4700051846057 70.131726460536 113.608472124417 116.791477649484 +DARS 38.7224080599416 34.3533605383033 37.8409715208489 40.8180094012176 +LYPLA1 93.4001823759454 93.7952703532382 110.207003230437 110.723737076862 +NPEPL1 11.1632999525471 11.411934144719 8.63404108137208 7.81197403479475 +CLMN 12.5467232858162 10.4012280846921 14.2745285958042 16.1101636493898 +CCS 19.2485876030541 17.2478068892439 14.486814840687 13.9066399867751 +GLRX3 51.3850823935252 47.6172579509854 59.4405830022299 51.8390756843507 +AKT2 39.9786849937726 35.9228388330875 40.9413837100873 41.1320350111131 +LRFN4 5.34899711497463 4.25752145132734 2.66538471320064 2.45874014925214 +UPB1 137.978978939196 117.601515985786 180.572225672557 179.599232945968 +MRC1 28.4250340467392 28.2415990516146 54.7160669245901 53.6058504720389 +AHCYL2 3.14236397784828 3.2466131871954 3.44395538021302 2.92255430767174 +STUB1 68.7602393743469 60.2286653440648 53.8368877804345 56.9809862383841 +GRK2 15.4424443741516 12.4465089076506 14.6096205697856 14.6979459524562 +OTC 138.466156338252 157.57799348469 273.808880613112 270.052942255212 +CAPN5 21.2091673020992 18.8875021284175 9.46963318385199 10.5951609536104 +FLII 16.1000398425055 15.977897746186 13.2168400146394 13.9640154014491 +CAPN2 15.0516943283234 15.9438152608355 22.5452008449594 22.211470565265 +CAPN1 13.0308394293735 13.7726319291778 11.9358814901519 11.7901864237316 +PIR 15.2946068503444 15.9577617737012 14.4557060586665 12.2676571541403 +SEPT11 12.1716981005475 11.5179918501659 8.8053138616636 9.01664543880227 +SEPT10 33.3858108594322 33.6869348724123 28.7685437918761 26.4009442263406 +ENTPD5 295.080059799864 294.350284733747 223.765640687606 218.668397525718 +SPAG9 9.39790471228059 13.2371224901889 14.1408299994527 14.612054689517 +COG3 11.697956701029 13.9581192902399 10.8186555200671 10.7493535362385 +SMS 57.4371276473835 61.9864574684399 74.5484192211007 74.2507461783843 +P4HB 1447.78091838092 1399.47746106023 598.515886351566 615.429739393368 +CHTOP 43.309920545955 40.467826724763 51.2290345038511 49.4078965132042 +COG7 7.17257278743795 6.11541636546198 6.73774243610311 6.43388202282192 +SARAF 185.583976326125 191.213173803603 177.075509770733 179.809417970622 +ENTPD8 72.6921074732973 64.6388182353148 58.2568482012416 63.1454014347341 +OSTF1 38.4311153166049 36.4337419554113 39.4525968704377 37.2159956043741 +SERPINB1 9.70591634395183 12.9350331288031 15.2544376665142 18.9272188352807 +SERPINB2 3.36774443407445 3.97574712494179 4.71205691991618 4.58658322589248 +SERPINB4 -0.079047357682769 0.132114255551186 -0.0029625310582175 0.175690979646858 +SERPINB6 162.369611934834 161.940232439158 183.684335742308 180.968287661977 +NFS1 30.9683740880421 29.2402474692227 28.4601785077488 31.7671330363925 +ENSBTAG00000048257 0.559431411320046 0.390026669491505 0.263614598678864 0.275281043168892 +UBC 1306.11381614139 1228.08585929291 1045.93308779187 1039.44809370649 +ELP2 17.5944837571123 14.7766978755244 18.2182386109071 16.2965752014127 +ELP1 73.2041064135595 80.7819713180969 56.2647918431716 54.8709648767207 +SPC24 86.1397068760754 72.7344787397279 20.3332128267164 17.3105536637349 +NRDC 22.1661984379327 24.1618529101052 24.5454870617835 22.6647869248971 +METAP1 5.17419288094435 5.99570353591726 7.07168660528538 7.59782938588372 +DES 5.26185003078461 5.56901216174059 6.36068772714828 7.13056794448223 +MSH2 6.64893482014723 7.30223379281484 5.73180848539311 6.43761531104763 +DCTN2 80.2842285464399 74.9257488465867 79.3876186822184 77.8795203321137 +AKR1A1 147.873392942131 142.696667547484 165.983285967683 159.274330419476 +SPRYD4 23.0067002331194 19.1468818185694 22.2044904337328 22.692682989685 +ST13 87.0669283980403 91.5086119883478 91.6834698239056 91.9448474108569 +PTGFRN 5.73416939018536 5.03098184103303 9.06727716933296 8.63705450374878 +PLXNB2 48.1564434456056 43.4556075122238 46.1731564130092 44.9997823336943 +TRIM56 2.74196888595672 3.22997464425685 3.88701020634711 2.65570302490392 +TCTN3 1.37332802360419 2.80599521456911 2.59419533594251 2.29494403644991 +DDX6 27.0966481220196 29.3211086323724 34.9288770618356 34.467821336165 +ENSBTAG00000022590 76.7461540081417 79.9509449949744 100.880974689103 103.339624303716 +HDDC3 13.1484680090362 13.0004662107067 15.8692797328677 16.7209377799052 +CMAS 67.6653261821093 76.8772043563647 60.1290182027096 61.8646415071146 +LANCL1 13.7590502930066 14.1162526414281 17.8112926819781 18.0975442325741 +PCBP2 286.876453642224 287.232570350163 297.36452601442 289.712150031604 +PCBP1 195.593312761682 183.448512196927 171.049128586068 171.065887188144 +GBA3 119.667137044925 128.548174445968 199.465584574088 188.450597724014 +NPEPPS 13.3064761799487 14.9107892176481 12.6302260365787 12.0646615424779 +AMT 39.578926327583 35.4897873667742 23.1374715107363 23.6069621857005 +SMC1A 14.4820471921868 17.0341152087521 18.7425067260268 17.9399727555068 +SIRT2 90.9545287654828 78.5697906924449 77.3881523531207 75.3460744535111 +RAB7A 97.6443843580372 79.0139903102592 88.8245674864513 86.3231924596 +NR4A1 0.798369184271407 0.563778483476415 0.840433072033014 0.952806971960205 +GNPNAT1 28.789991598033 29.7986842095603 24.1037290013149 24.9579941692512 +SIRT5 29.8358541205021 29.4789259254726 32.8573233601972 32.743199431297 +NDUFV2 116.507947118683 127.593259652414 93.8320711894945 98.4922249395658 +SGTA 27.9843254888222 27.3284315762744 27.1685366631665 26.0608612474229 +TMEM11 13.7691597725947 11.8109772587446 11.3788685462792 11.1743267586244 +TRIM47 9.65115652325246 10.4699729838649 8.09976244810246 7.55098511026538 +PLEK 30.8323882786404 30.4111674296428 57.2282908228883 58.5159295875576 +KIF3A 4.89786567524035 4.28368246721868 3.49175850451969 4.60957602997618 +PEX1 15.4544197838958 16.0244906457564 18.9561782921643 18.2255231472698 +HADH 210.689026188234 217.9191795525 249.708589160134 254.125083762801 +PEX5 32.1369626101149 31.9458648987082 29.1619532182806 29.7444510949946 +PEX6 11.5789877435837 11.7746629922933 12.4246599050693 10.8149484928433 +TKFC 113.413234004007 106.441641387868 113.764144436118 114.423299096433 +NWD2 0.0087352876352545 0.164049820185391 0.0231257392180691 0.00873832802978505 +RBM25 15.1477331274945 16.1323097339573 18.1302063803734 20.502739073014 +PPP2R1A 52.6290620342151 52.3267720036388 44.4479961627477 43.07173459743 +ENSBTAG00000012692 0.763230968602553 0.363473722405054 2.21189803338214 1.50967310374531 +ATP5S 9.52186499214402 8.37182392681633 10.8649920755077 10.750845107456 +ENSBTAG00000026812 0.216520059278631 0.599221559684165 0.107533575916178 0.119803628735598 +STAMBP 6.82228858025201 11.202332123536 10.3726215272431 11.6931646522005 +NEB -0.0486945133955257 0.175696734303736 0.0326596235567223 0.0384734738321251 +APOOL 19.9277057841037 25.1628668643323 21.6014542614713 22.2459889042822 +HNRNPH1 159.531708330291 172.906314087914 185.661697361728 181.74399171698 +HNRNPH3 46.9982939180379 46.2490424151402 55.050384311013 52.1387804290025 +HNRNPH2 33.0032853362216 28.8578692242181 31.6099306421129 32.933576088082 +PLRG1 22.269317819574 23.0818556408505 22.2341588839468 19.4486314912393 +GNAI2 49.3856108025701 48.1374939930287 49.4805540435982 45.4799019776422 +GNAI3 39.3498009708115 38.6076017598183 40.8273707028315 40.9975692158404 +GNAI1 5.38717079521801 6.55105101163798 5.7904173013258 5.74007366365365 +MRPS34 52.705045705434 45.7650214449315 45.3620274487769 43.1297154798177 +AFMID 14.220222829881 19.8597985643439 37.6868628464579 38.366878278672 +MRPS30 11.7492006541413 14.1029736098962 13.274926142087 15.6184397328951 +HSPA12B 2.9030654336603 3.77027914129879 1.80896022062297 2.09210800717526 +STRN3 8.13498273725566 9.03287948300691 9.96295487170499 9.74576994193983 +ABHD16A 25.3054122555458 26.233175139912 26.234971162757 24.540897169109 +MTHFR 43.7095678334941 40.3222262829902 34.7976976778121 30.7237438948094 +MTHFS 70.3833137291695 70.679509811558 102.556433076768 100.724993245525 +PDSS2 5.25999828472556 5.84962797660508 8.22558650975668 7.80933981180359 +DTNB 27.4313027239405 26.4798904549263 28.3829068441411 27.5076278153581 +VCAM1 13.680654708315 17.3293688002081 38.4925311352473 37.6009766180847 +PREP 15.4744582349564 16.4324443864566 16.7954108709843 15.594271211927 +SYNE1 11.0916406094501 9.21704055885757 16.3298111824976 15.1668017273714 +SYNE3 3.4446382739788 4.01611649224488 3.8549713323667 4.07364934958814 +GOPC 6.33820876794039 7.8874717583141 12.4015336870358 12.6362543998745 +HNRNPUL1 42.40032600177 38.6102688921157 40.5058304569221 39.0894072854499 +YTHDC1 21.5377532702991 23.7265581376159 32.8803561238731 30.9353196589496 +PCMT1 41.61148897908 37.4395975309916 35.7497783754378 32.2292270688327 +BSG 663.785069995599 632.722524179613 601.694224705993 601.133236499985 +CNTLN 2.23485941057118 1.97886648814255 1.99177526945859 2.63606441370194 +DCHS1 1.36557467048848 1.25064183852721 1.40062046026667 1.2296385964705 +STOML2 56.8286035016604 50.5260871677952 48.7696370839438 44.9884366104539 +PDE4DIP 11.1423223963941 13.7719434810164 10.4336922887578 10.2364032945622 +ADA 26.338096785246 22.9731678890392 42.8827458443435 43.2618442115953 +VPS16 12.5295200567067 11.6675007150994 10.373029920922 10.4987674553771 +EP400 3.47402502081295 3.22421262142185 4.2240158951896 4.26426291360327 +RNH1 35.9380261163109 32.4428801804597 28.1988346840832 32.0434157279718 +RPS13 522.867553382692 476.389183703835 583.955752581489 542.373904666156 +CLPX 82.8384393793781 86.7446804663212 78.4926414724142 75.1445061085399 +RPS11 1300.27222977494 1263.75677368172 1107.3997992002 1075.72506242072 +RPS10 773.66442045445 700.250863105942 621.707706799805 599.645940406373 +RPS17 1097.80248416591 1074.74808676663 994.761525464613 1023.29527693177 +RPS16 693.49583992307 659.756831891863 596.849837193293 608.448053821041 +RPS14 814.303129173723 769.076385732174 804.065056879404 806.113208187967 +ARL1 55.3318944653916 55.5839765995688 54.2862288307767 56.5737763704549 +CLPP 38.0094932542324 32.2076248154063 28.53859864377 29.7845812505223 +RPS19 944.557320387324 910.016421179541 682.146812911003 657.995562380484 +CCDC22 5.90040309658244 5.08327308934923 5.68813930547208 4.7336845474858 +CCDC25 32.4659933535804 27.1194858920637 43.1976813779266 43.6545262873574 +FIBP 25.8057688206942 23.4025493699871 22.6728081635671 22.0077244549518 +ALDH3B1 4.46352587715083 4.09715096214455 2.42315710412378 2.37007095906671 +DCAF11 136.885754549088 131.757345348128 95.4010531900795 97.1412219513151 +DDOST 85.0129547809851 73.5086852947942 67.239745678429 68.1401793610268 +MGC152281 102.415875552095 104.685711832215 129.315818173451 125.232138372636 +RRM1 48.3806745577983 49.1148715360649 39.0920661012792 37.5880640591606 +CLPB 3.50635886825423 3.78197143718082 5.29679088433362 5.22156068923039 +PUSL1 2.13622208970231 1.99192840696824 1.19592393393788 1.55894630451249 +DERA 49.1860075519892 54.8260709502859 47.0988173171878 49.2614372027992 +BROX 14.7426855767455 15.3451037982629 16.6553714851895 18.2604718071955 +TXN 506.086095336058 515.47711746809 447.946314697442 444.253307951748 +PAPSS2 71.7393450568925 70.6035600964772 69.7786480109247 70.5873847244192 +SLC9A3R2 66.4374827655652 56.7694377822109 69.8254270255267 69.1811549274692 +SLC9A3R1 185.615220840609 175.391593167531 137.437815169588 136.489240314059 +UBQLN1 83.882327080875 86.0749610529681 94.0960493344733 87.9742133526067 +LSM12 19.918177286138 18.6245000221205 21.2007742447329 19.2031389600604 +GCLC 44.7367346882868 39.8881248318436 45.1429474689259 50.5907908082858 +CASP7 10.419954448464 13.060099156642 15.3134620135647 14.6167893297013 +TF 8599.29461693456 9413.46115141257 14863.2413697457 14658.9887904924 +CYP2C18 37.6036495412475 39.973800687212 87.4972610661016 86.6294637668997 +OAS1Y 71.4302797075208 58.6873827460939 41.5782295485235 42.8477851529766 +OAS1X 13.8527954937797 13.6602642078607 10.2841849717523 13.4172035850375 +TFAM 10.4472318537323 11.2605458526036 16.0983068607753 17.4348089370442 +TXNL1 103.952552838255 115.038879495926 108.137244958645 112.278541020715 +SSSCA1 13.2121493626686 13.4288704338149 12.106571944501 10.4596059211301 +ENSBTAG00000000229 119.736087504913 125.132146656163 166.191572173849 164.294745269921 +GGT1 40.0843787247375 36.8874604868939 33.9901946014926 36.1954946909655 +TMX1 15.9009292608672 13.8914500843861 14.9617040218007 15.5309986516919 +NAGA 26.6121506957114 21.7050881819476 17.3447774476791 16.7438518243868 +NAGK 13.5529503195623 13.2757539739551 14.522493003992 13.5344730711148 +ACTN2 0.159043176887113 0.357710597533324 0.215480557633423 0.226665004259558 +ACTN1 24.1018203431991 22.019177687976 26.4045345156663 26.2671766468744 +CYP4A11 579.085869415823 587.848406930167 512.732683446841 514.542921241511 +ACTN4 100.633352280165 89.499926365866 67.1056812644732 68.4497784723153 +EZR 17.5041415080775 17.6369564693945 20.3298980060406 21.5370597198522 +GLYAT 1620.75641806911 1632.20607950237 1680.52602930246 1642.67906576899 +G3BP2 20.2581753634458 23.5313252466533 26.5404963119162 25.8373194464335 +PTPRM 9.15356066519333 8.57338509420922 13.8393657908032 13.0773782679421 +MYO7B 0.317952609778197 0.385858442819635 0.290044468187566 0.281728139410924 +STK10 15.4438125974873 15.1764646706086 17.0622387797986 16.8332595219954 +FKBP4 109.962968327887 102.241124718474 75.9741798496794 79.6174005777913 +SRSF10 48.3568872566459 51.4706979283994 50.5540306357587 49.1405405017313 +SEC23IP 9.77200823083704 11.0708718455968 11.213586181304 11.2258813683553 +FKBP3 43.266105478479 45.0021463291844 44.3906742907561 45.8929712493271 +FKBP8 99.574923967891 87.9015166600516 79.1429696024693 82.8317968948386 +GAPVD1 9.86245274838146 9.32589783262592 11.5069316375072 10.7711795313778 +SGPL1 35.1386435476099 30.9329642058262 54.1032160617031 54.0236410927655 +NDUFB8 116.834440126871 106.77329850885 108.730135845698 105.119014894694 +PPME1 14.5423492080999 17.2466823738509 14.8535177466358 15.9678749096679 +MANF 126.068146487134 126.773584164756 58.1224386487062 55.5531406663572 +HEBP1 155.206094699601 179.329719859147 208.236513315194 210.049818840196 +HBS1L 27.2220885680969 28.0024864704943 25.6632174505036 24.7007330892689 +VAC14 13.2801399855225 10.3819795490546 10.3087606047789 11.9164104939034 +WDR5 34.4262631249817 31.8444048037985 28.299631022021 33.1309167894989 +MAN2C1 8.23484281989396 8.05661177788604 7.93201461056424 8.63637774766572 +WDR1 30.7775670697141 28.4040154313901 26.3602696218109 25.6153008535878 +ZFYVE21 68.3132874381588 52.4480368665496 59.2629841310042 61.0504589739928 +APRT 77.4568082297743 67.9739048495469 77.492231948105 83.0519088357615 +CSNK1A1 51.2260737435172 54.0172337031947 58.5773442109201 61.1836671772787 +ABLIM1 20.9208625745434 20.1022950185073 24.4217838324811 22.7551418029438 +JCHAIN 30.0430054978903 23.5539451773765 22.3582374231222 25.7092912501054 +SULT1E1 10.8335871648389 12.9503437186598 18.0102528899749 15.7331713087382 +L2HGDH 4.47577243397739 4.79422041196904 7.36094951756975 6.69809994979611 +SNAP23 15.9538302317801 16.9981803623118 23.6728808248383 23.8363449567666 +TOP2B 17.0653177217484 17.9526171454953 26.278514094742 26.5253226266516 +GM2A 18.2362831739595 21.117271532756 36.731549162245 32.3249918586048 +LACTB 16.1950415825112 15.1687301096019 16.9444987027527 16.5549321922178 +CSRP1 19.1158506905572 14.4858187010906 12.0871307380947 12.8503511823462 +CSRP2 42.7902963085357 44.4432386922299 47.2066861371693 39.1844294702836 +SUCLA2 10.4391346986634 13.5307853969249 11.0637850299061 8.76010784363216 +HHIP 14.5039157346216 11.8517190223921 17.4821834687607 18.8113867036974 +HSD17B12 77.7719103294517 82.3126812575161 48.2217763211841 46.7361450055157 +HSD17B13 1614.69404422453 1690.40087160756 721.683579870367 723.524640259076 +HSD17B10 891.400486239166 840.692626126069 673.07621316047 658.419640203595 +20ALPHA-HSD 1.94219504579959 0.855479552240382 1.37886004846924 0.973692840855602 +ATP6V1A 21.9172580964765 21.0254969442724 27.0481564564741 27.9115409524926 +HSD17B14 47.1228561730785 43.7225291170798 53.8278653093109 60.2647092117435 +BBOX1 208.791109755464 218.781940540238 261.552208259923 259.24452608955 +EMD 25.3227991241643 26.3464811374135 18.2107640920701 20.2162347649282 +ATP6V1E1 36.2535465594273 30.4338578853761 31.1395105692237 33.3171865243901 +UOX 16.9418883020323 12.9545322847907 81.251734915381 77.1966659797797 +ATP6V1H 10.1054999422333 10.7974511717945 11.8287212195442 11.6651404038888 +RAB6B -0.0796433237878804 0.29498976023963 0.0321186379033785 0.00984058321829792 +MX1 13.5871860929952 11.9785586416949 13.2066483556842 16.4032429052869 +SFXN5 4.79762115778554 6.98575552079888 8.17098087735151 6.15268160158786 +SFXN2 17.6044106332051 19.7122601039609 13.2443461514536 13.1194745665728 +SFXN1 41.5031262618955 45.8867996687204 47.4492995083688 47.3756481245606 +UROD 57.3160850539888 56.333613544218 56.2698947638903 57.4559948253489 +IFIT5 31.8349872983945 34.995449472613 37.6889524507771 36.2242327459588 +LMO7 15.8348911355402 15.2718539418278 16.6079589370498 16.5589920860694 +CCT8 65.2096353452967 75.0874590546435 63.6872681420151 63.3444330706543 +ENSBTAG00000032453 -0.109586111976307 1.05907792777529 0.440291921400709 0.450676672660541 +CCT2 73.4862288415183 71.6893477904709 71.3385445545297 73.86749649934 +CCT3 76.5428835932819 78.7147281760493 62.7291075803548 63.7578986708214 +CCT7 65.2982449940596 59.3812202066599 48.765886822457 47.1382178885552 +CCT4 78.3678484120151 82.3677441349927 66.3962409609487 70.2438018787458 +CCT5 53.5370726039037 50.5769668076478 40.8800204518481 37.6624937890349 +EFTUD2 14.1034930826789 12.2061057315692 12.9859663721995 12.3626121406912 +C4A 801.169854757233 775.852008407187 1038.39579920479 1038.7108087384 +ENSBTAG00000026133 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +C14H8orf82 12.9685783409366 11.7896829341325 10.8945936531737 9.76712837584875 +PDLIM5 24.4523194909809 26.21478008159 30.2204227493468 30.5144087803354 +PDLIM1 48.9441650688375 48.4924288013859 51.109801888032 44.4207242959783 +PDLIM3 4.98471758129181 6.0683167986955 4.9344709988019 4.36717785844193 +BRCC3 18.3537614112121 20.6539025650382 24.099741237318 28.4432797609603 +AKTIP 10.202903112929 11.2959771811719 10.2591814243062 11.0434153316157 +ENSBTAG00000048287 149.05477666269 99.7346905915885 141.419375673324 115.214214044895 +RAP1GDS1 7.57914208897516 10.0291935433649 6.46253529867549 7.36991257217177 +GDI2 188.676057401403 200.45626894746 172.647652487407 168.412847546611 +DHRS1 171.909874851457 160.762362121018 106.672713726251 102.789276421766 +GDI1 47.0244804225268 45.2204308839204 45.855978939476 48.0025472140323 +MCCC2 16.0314104791439 20.865612904431 23.9911712685723 22.4239222791931 +MCCC1 38.0454538940768 36.8027989657298 42.8439918204121 44.7044962684895 +PAFAH2 44.0469544575759 41.3618576212055 32.9528830772532 35.4582251643708 +ERLIN2 68.0978853046623 65.3694653269437 78.6288219066459 78.4463650261116 +GFM1 29.9801082462597 31.6974498499095 36.7371995301849 35.6763765938689 +GFM2 18.1180888512257 19.0706325565877 18.6437316190765 18.8678516983431 +CBS 50.275469678549 50.7061605026127 41.8564919045229 41.1033917891441 +ENSBTAG00000034850 7.19255438753177 9.07771322969325 4.89673347612519 7.23189695492511 +FLNB 15.1599416220712 13.5285964590462 14.9154961383453 14.4015827376836 +EIF4A1 95.0807961297107 94.5152709723596 77.0997675129749 75.6243230370453 +EIF4A3 35.6749587239255 35.3978151101994 33.8199276975183 32.2993887324336 +KRT18 218.093238702214 216.3618602256 116.427632225427 113.747637654905 +CAPNS1 86.9562244268314 84.7842609047457 88.1861844618468 89.3024479094432 +CROT 225.143883617479 239.268141825478 200.295875820315 195.980140971379 +LETM1 18.7933925033172 16.6379513377632 12.5957388231499 10.9328391475656 +TMPRSS3 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +PRKCSH 99.6668486746383 94.4108487755093 86.6658798074426 88.5917296376608 +TAF15 37.4864719347854 34.6520579740238 44.8786809555305 46.7109671660824 +FH 99.427560200047 108.767823645757 111.589459406576 109.787671728654 +DCTN3 28.2141590590715 30.347221263962 30.639630320406 25.2663941692082 +DCTN1 16.8835816086212 17.8557283155233 17.7829887929069 17.6683513508846 +RNASET2 28.0397273261063 27.7651311363531 35.3051340456282 35.2290014780888 +NDUFV3 45.1067976349019 47.4721643782035 36.2475069858111 35.4449385592524 +PKLR 40.281523908341 34.2991045623882 68.7811449831403 66.0826426071171 +NDUFV1 89.7912403998105 79.4699969480042 65.7334369347194 66.2146523215109 +RPS4Y1 59.6872774571047 50.357517369007 36.6320736415744 41.3407159445932 +ASPA 2.62833635034221 2.88632930108215 2.74381609101679 2.91334361050854 +FAM186A -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +ASPN 23.4557853898405 25.9195127497061 33.3056106011246 32.1552124892458 +SERF2 1220.89729708647 1159.98486074744 831.972393427435 838.48508352013 +ASPH 72.0647703953054 66.9963068048453 68.3878682774177 70.5719675637984 +CYP39A1 23.9290557700249 24.6572744691595 26.892708348116 27.7742496982802 +RBM15 5.37528324737828 4.17041563941325 5.01944209583531 6.21856864373041 +RBM14 29.3536158786837 24.5546159293507 22.3542103480944 21.2932829280388 +PARVA 19.7052744111987 20.084570326936 32.1304426470257 36.2068742144069 +GGH 68.1429129930792 73.4535733281278 54.0227443123657 56.2613565928326 +NEXN 0.605094853940956 0.756782756357016 0.345223717661467 0.356747857340383 +MVP 35.5323014157723 33.4652297049853 28.2955565985349 28.560847775963 +LAMA2 0.170572527481738 0.543253387069354 0.17315800626322 0.131801598359233 +PSMD6 42.9764534127594 40.4951715867558 40.7268914985099 39.5200663098277 +LAMA5 5.37977218063479 5.09480839712849 3.8840305439793 3.64405317823273 +ARVCF 28.4167579749895 21.144480988249 20.6116172053356 21.7296136533985 +NAT1 45.3624929481399 45.0042938580826 53.3196661379433 49.0306915720927 +QPCTL 10.8934317641201 10.3611675832642 6.14801335202803 7.31840758432045 +FAM96A 83.5604033977766 81.8753339485662 100.705098471446 97.7509813736637 +ALDH9A1 369.60100412425 375.652906892365 467.513663330321 468.29409380829 +BPHL 37.0957702822177 36.3848642677326 36.8457200777081 37.6934445546045 +GLO1 224.717787601532 249.987787205914 256.943179224681 262.72104028686 +MVK 125.60023181104 108.228518627115 40.4961111521754 44.7611642620467 +ASRGL1 33.5773968102396 38.1004162020057 31.506081441533 23.8969301772807 +CMBL 244.547761199155 247.824305499274 212.5544579795 219.650090922384 +F7 89.3108883537718 79.657979284652 82.7400359105883 79.2599059032245 +F9 426.804996325805 449.261708949094 657.682836206112 671.683971414569 +LSP1 10.685143012409 9.16574359799813 9.44647670536338 8.79633772094805 +GSTZ1 481.724381644991 455.349139899186 373.854825072395 374.300472586966 +MARS 15.3764472503945 13.8439726646603 10.945887674502 11.726932700481 +TUBGCP2 15.5505209369877 16.5477224752994 14.9213950249214 12.7635934511203 +CUL3 15.8704700674725 17.4373319348964 19.5001816059124 20.0057604295144 +NBEAL1 4.9137281277519 4.53394265347196 5.67717614153071 5.75377544684986 +CFD 169.572889666805 153.74770435413 271.203175210289 265.400065153213 +VAV2 12.6516175724925 12.0941203194214 11.3925137259513 12.1189190596617 +PSMD9 23.584959735025 25.9427439127782 24.1683615907499 25.4170844088805 +PSMD8 78.9155023047106 72.084579475786 64.5484277164876 66.7238457648302 +PSMD5 19.2251994427441 19.7371391961841 18.1467352758453 19.6527044093147 +PSMD4 74.0916859676512 69.8503533971009 53.2759828432836 56.7207402594667 +PSMD7 66.3621270037664 67.8644378082165 56.0752946369566 56.8458842451995 +FLAD1 50.2968340545894 44.4697945876749 23.6174173285843 24.7786715369235 +PSMD1 45.6762609644219 49.9714910712316 42.9877891606649 41.2035152789946 +PSMD3 68.7214343109245 63.8492567116916 52.5687704959083 51.2853211038092 +PSMD2 66.4527031810412 69.9147686122521 54.8433695195866 53.3526890528518 +CTNNB1 90.4023761157358 94.2750388257147 108.506696375932 113.964268569156 +NGFR 19.1774697255707 18.0444728424581 26.6718407687433 27.510004777236 +CPSF7 13.8229252870417 12.5535338220972 14.0785685250771 14.13059212865 +MOB1A 17.1161090658869 19.8665198600251 27.3172587044961 25.489204435624 +CPSF3 13.5551056525383 10.815894113857 12.0101451807324 13.4628356627835 +CPSF2 12.7661162149239 11.993364680498 11.7267251606951 12.3843592141942 +CPSF1 10.5691038631671 9.71324877219874 8.44757539251843 8.37712425810752 +EPS15 26.6887488463586 28.6326444493031 28.1434880218617 29.9773339337446 +QKI 32.2514136114333 30.7416864445002 50.0541146635714 46.8031940398972 +ENSBTAG00000014220 306.638646627431 323.210113710557 673.515631149979 668.28946463748 +MAD1L1 3.55481954610918 3.91530353255797 3.71601168804164 2.78618622837252 +CATHL2 -0.0818278270922784 0.442435441480108 -5.98126814062572e-05 0.0122583485392512 +CATHL3 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +CATHL1 -0.0829887190073607 0.50247898753471 0.00115212019722091 0.0135432008935647 +HSD17B8 60.4396472715786 58.6775582149661 52.9804491462764 53.1333013601698 +HMGCL 81.6564342326211 71.1276535423798 105.068100355329 100.787743958003 +ACAA1 666.983826883534 626.614972747982 599.533308779113 584.456666588973 +ILVBL 43.9792942485372 40.2561199484798 36.5702195393003 39.2678639478191 +CNOT7 55.8648458541427 59.7597469723131 64.9942217227111 58.8878336221171 +HSD17B6 870.388208687256 893.578986665181 743.77417131561 752.508349522779 +HSD17B7 56.1195772229482 60.9560861879787 36.8843720374126 35.7389118187248 +ITGB1 80.0144485394017 90.6487986872208 87.0877351821985 86.517405225761 +ITGB3 14.8960084727247 17.3223072479106 23.7762578498425 21.4064864572844 +ENSBTAG00000039289 32.3199552668778 35.0880352545981 13.3313286585454 11.9553262202517 +ITGB5 53.2409932243542 52.8868652524672 63.3156349727449 65.0853331632312 +ITGB6 0.249409563345128 0.423590544960952 0.273549409492523 0.0775742434811864 +RTN4 234.420300375363 248.412045892992 262.078709884684 253.338160818239 +HAX1 29.6499633498052 27.2720483057226 27.4691710571091 25.5606703788432 +KPNB1 38.5863928993263 39.5934007060507 32.8980606930222 34.0116038913187 +HGS 19.8591419118765 17.0893346072986 16.2013949614545 16.5194381610456 +R3HDM1 3.73238709317183 4.51682543882832 3.2322272091072 3.51674048192889 +MST1 187.863010724972 176.96789577774 158.925524640767 159.791818306159 +HGD 907.379627269024 936.063625032695 911.160754243876 915.2077258314 +PRMT5 19.1367468832104 18.4210129182983 14.4054343631021 15.4746265283109 +COPS7B 10.8711954237715 8.60426859215828 8.62808031838259 8.81889986745711 +COPS7A 34.1163113080537 35.5617824243021 32.8001678081673 32.891594608121 +CRAT 138.027999952401 131.944493882948 95.2372236771034 97.4378295153783 +PPFIA1 10.5155743913038 12.2298732559008 8.73034800129126 9.73573303176059 +MYO6 10.9630981523458 12.5649633983582 15.3159298780359 16.0232880966266 +RABGGTB 46.5237313596009 48.3817508110802 60.8431745012983 58.6706823906761 +NAP1L4 14.974542241789 13.9449104036876 15.7924973150127 16.7832295545638 +KIF13B 3.08733216577438 3.27128041761237 4.49878228245069 4.38267392165231 +RABGGTA 7.3595766089214 6.47852923342972 6.18478112958811 5.59796425700703 +ENSBTAG00000019601 6.38828637783438 4.695896961653 8.0658783655894 8.40329733438033 +FSHB -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +ENSBTAG00000044137 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +HUWE1 21.953457255099 22.1564759750859 23.6551714742396 24.1416329925867 +MAT1A 354.960760536584 357.690700885961 287.969854665606 286.511742610089 +EHD4 2.17321268496178 2.98809620585801 3.21592757431054 3.15273057021539 +PKP2 13.5677400574093 15.7561518320554 14.0623856059251 14.2440263289709 +EHD3 31.0561478467807 32.5178885205977 26.3449400771294 25.7492304925835 +SLC25A15 56.0156525373645 56.0884032946413 70.7452547656337 69.4521670687551 +SLC25A13 70.9358742422142 69.7139311466039 80.5462649068889 77.9229970417751 +SLC25A12 1.59243613732084 2.47469492633696 2.32810352549483 1.93522547053468 +SLC25A11 74.6674776848938 69.2909451570188 48.7072360068212 53.3902284772163 +PEBP1 599.423907718042 622.794245834889 548.395830489935 546.566290034157 +ACAA2 971.293504421636 972.813793950403 900.453388863264 895.573327805747 +CNOT9 33.4909386892945 32.0798746018683 29.7260429422648 30.4652249957747 +NDUFA10 102.853069919572 99.219581100168 90.6144432392249 92.0224578485191 +FGG 5510.2935797276 6314.27184133987 11231.9665905182 11083.1964226963 +METTL7A 145.105674790594 158.11249136213 130.85265748075 136.43344920365 +METTL7B 662.708723537358 628.777270051081 664.035031352578 661.586983281126 +TOR1AIP2 34.4303344781486 36.847490681172 36.3211496118583 34.4005219005459 +PLBD2 61.2613400394014 50.5875842503906 50.3862800788933 48.5936223986162 +ACIN1 37.3372130208879 32.8432390110725 34.1065639435825 35.9000830831859 +ATP1B3 79.6911875076286 80.8097383802677 101.637803194136 102.821955923537 +LPP 2.0848247876603 2.12852951347651 2.85692176936984 2.42292506409957 +TNFRSF21 10.0032215520589 10.4584077995179 12.6609288069883 12.5119183500425 +PSMC2 74.8535331077659 76.213667379699 73.3431290090272 76.0591654673721 +SYNCRIP 28.0498677872575 27.8974678713868 28.3510155876832 29.5605565350557 +FCGRT 339.123714831448 349.184831291228 252.702187428348 250.432301807155 +HSD17B4 175.444508237151 190.228770203727 255.669271123696 260.084718748588 +ALDH1L1 502.936375854061 464.176289612175 453.536262985667 455.274529767133 +MPV17L 66.640777442221 71.527555826463 98.3483975641913 103.652497759949 +C1QC 344.861583282395 325.421277264457 525.421953271192 533.38200242438 +C1QB 481.237144170125 490.41660242652 800.625180824222 801.875667357447 +VIM 62.9537732423271 60.8390865487559 39.9415715465352 35.3390483795712 +EFL1 6.41987287199359 6.30959028220535 6.42945242027547 7.12039780826087 +TRA2B 80.0873556873048 82.1481704720508 94.4367626688121 91.8466824543424 +PHB 225.988013266387 242.775297109345 128.77787891159 129.168363765246 +MMAA 14.5392068170328 17.7840075024986 15.0202675223713 15.3960781000958 +ALDH5A1 46.1538544226456 47.4165664771752 59.8693328624112 55.7862710350699 +MMAB 80.4271741247078 74.9685355721722 47.7027383495691 52.2156296559744 +OSBP 40.1526371964496 36.546038436398 20.138982971892 23.6795340377995 +PTPN11 19.5801355725469 20.0997703808865 21.3211932357642 21.405568562408 +DDAH2 7.85737335430685 6.86364964661057 3.3463448645452 3.35715270316569 +DIABLO 26.4695553027665 24.7689242662293 25.6650905496329 22.9606055953164 +SDR39U1 12.7669545495977 8.92022029985483 7.30008147081135 9.0899729177108 +SNX2 49.0728847319265 50.2430332838893 56.0726428143263 58.3353244967153 +PDXK 9.43592368260568 8.46579285370344 10.5317976794449 10.3115425130382 +CYB5R3 284.863861970978 262.877600327394 278.308510723211 287.532527016437 +SNX6 29.3295598153344 35.6001878862353 38.0651511896499 36.3913489088024 +CYB5R1 12.935088399628 11.6817429875198 11.1831878487094 11.0681430245406 +SNX4 14.1885086033544 14.7176591540344 19.1433618603585 17.5714956518342 +UGT3A2 89.6558611086346 94.9410548942997 103.35695433613 105.897829921947 +SPTAN1 53.1497076103341 49.9604039727133 32.196718230545 32.718008923137 +SNX9 52.9145554547342 47.9764849481738 55.6015235910902 55.6096787435439 +SPON1 3.20791943929005 3.77763378509912 1.67868013830304 2.07122925387532 +ALG5 46.1447504776606 45.3901615339994 39.5276684137686 43.1566671348597 +ITGB2 13.2880059064154 11.15881281222 25.7424553328817 23.3575050104728 +MASP2 109.757661125152 102.434375495997 122.865579874724 123.642395996841 +PDXP 7.33248210403713 9.2697633087992 14.5172984181007 13.8296738658523 +FUK 7.66025384632415 6.40299746772712 7.70002511032626 7.55087592169548 +CCDC127 22.1748049474124 22.152104953827 17.9498634537099 19.0952095629423 +NOS3 3.72382889484879 3.9860277242737 3.79252110388413 3.79126538999694 +RAB11A 46.9279198450475 44.8067862012385 44.6012944161902 52.5993270084546 +GCC2 6.97736853723239 6.72899635179618 10.0269825114493 10.2973266044703 +ENSBTAG00000046676 -0.112521348070538 0.0927129420961553 1.9692332110929 0.0462293342776494 +PKM 17.3785080980981 16.4246956212203 15.8341113511072 18.9287438762599 +TMED7 134.157735892375 142.246911243448 128.930018895078 124.344766578459 +BLA-DQB 97.7776084055453 87.8573328912113 152.652618509455 153.440733072895 +CSK 18.4433519174961 16.4010224338902 17.0602152928349 17.801201833264 +DAP3 21.1135263854204 22.4838795287676 21.0486931091096 18.5911551819558 +TNPO1 9.47597275039236 11.1399315389253 15.1471323898426 14.6272719157857 +EIF4E 20.6609628628263 22.9936105854576 19.0944447106385 18.4295610540584 +TELO2 3.14546246964801 2.3688263878156 2.36405585305046 2.21825599336677 +CALU 94.9028452589509 97.414854987449 88.4403339338871 87.678618152211 +TUBB2A 8.59531975801329 8.22962253065591 6.08753287826305 5.79280033698288 +TUBB2B 5.86211450117737 6.37282522100032 7.43380456157977 7.12017536763833 +PAAF1 19.5995846541387 21.2820258119351 22.9807208120891 22.3644344588122 +CD99 52.1795040089466 52.8855141423455 59.374104853131 58.642203282358 +COMTD1 8.78509937385784 7.4014174846471 3.35612155809923 3.52061623154079 +TUBB 154.405961026434 149.347426096824 84.809547503305 84.4688995665526 +MAOB 313.288044173735 331.49945752127 352.586432596194 350.554050348732 +NAPRT 94.2703356313118 85.714928550308 80.4823510810017 90.1778972217913 +DTYMK 15.4910330076949 18.7528832325361 9.53466378497959 9.33148441195648 +NEIL3 1.81134714542466 1.84933590678147 0.687382725378244 0.435114461437356 +ENSBTAG00000048275 150.990401747644 153.737507192872 167.932878522908 175.489792762518 +MUT 307.404569721191 336.404460663145 354.662505732003 360.423405359379 +INMT 40.3647509474395 36.5846521237996 29.8437900002751 32.0277861739224 +CLYBL 41.5810371784141 37.0854339225884 41.6034504326415 40.8423689388688 +RFC2 8.79133401656378 9.39400432564624 9.15345760559741 9.55464269573716 +PGAM5 19.9322161014377 21.4755655512804 15.7581063433743 16.9355149204452 +TECR 201.692315625296 197.012804481707 124.242744786474 128.835442610018 +FABP1 6774.63561600088 7144.63380369229 3485.39377513447 3397.22090558008 +AKR1C4 762.85989571159 760.198672061513 646.916269172403 651.015929438599 +CBX3 4.91432947028941 5.43434739387541 3.65738612892386 2.97788852074107 +LCP1 19.1399735895813 22.9356673133425 33.8343929926513 32.3969381769299 +FECH 34.0232120463036 34.1201313953337 32.3233515960398 33.5713656077101 +AKR1C3 641.816733536881 649.487047967925 1358.72655798783 1342.80956758485 +ZBTB10 2.41685010798729 1.62946323876491 1.35766235302032 1.36653105570081 +SEH1L 16.7384980139056 18.7405463944324 15.9234022433981 17.8620645378003 +ENSBTAG00000008184 63.6029537596964 67.9619088452763 47.7222987056459 47.3340025023228 +CCDC51 14.0843755794836 13.4929523681656 12.1915808727873 9.60080792394418 +MRPL22 29.7541700095955 32.2307093346447 34.1366332276666 34.4767607326511 +C1QBP 44.8920926620059 46.0439330476433 36.6769028593392 39.4134073191318 +RAB18 78.1946218985596 87.3462102371973 76.0396414355268 78.25158083585 +ENSBTAG00000018680 7.42491424900198 7.78975718515808 10.3962880124524 10.1768996614646 +TRAPPC11 6.61476491614505 6.91474970691512 7.20658085831983 7.76851993055637 +TRAPPC12 5.75213247488064 6.01890126149679 4.77479924004409 4.59427919824109 +ENSBTAG00000047699 4.61405519324348 6.72068675055137 4.52409168320208 4.25329037970321 +RAB13 35.2598703457167 33.3398667710171 37.9637677006498 32.9755169169827 +SRP72 21.6244326221986 23.1590157628849 22.8977290912495 24.3854805968318 +RAB15 0.113570192753917 0.411753713521657 0.0871831044214716 0.0588171084018919 +RAB14 80.0733613188125 100.41371948323 118.82727897307 113.687805530295 +RAB17 37.4275161543508 38.2698160250429 38.1959730880395 38.4543390944868 +ASL 255.384861494669 249.715043770811 248.558068906637 240.242618426766 +RRAS2 16.9612580637517 15.7026444100204 19.4853507949078 18.3281540237465 +RAB1A 107.287442407347 118.338973606536 100.537079995058 95.1147686529333 +NAGLU 9.93785865034672 10.4225592197143 8.68588821399643 8.67117227273624 +FYN 10.3575586554311 9.27526487909106 13.2816404844821 12.0571425304466 +GMPPA 22.7111528483813 18.9625759401958 15.1355421251685 14.4932255693984 +GMPPB 13.8849747143113 14.8445714156175 10.6256841417244 11.352210424229 +ENSBTAG00000011330 80.9133099884856 79.6037430094293 79.9286405542379 84.0609334001863 +GNL1 9.39325515351537 8.48716596767357 8.39000974116531 6.51421353676947 +MTOR 8.47464913359724 8.49061039585572 7.67668949316077 7.90667289135427 +LAMP2 227.872755928791 242.180081058573 305.852684827018 316.864081707098 +ACADSB 3.76679934353406 3.63703916973838 5.69512938890654 4.12926198622542 +ALDH2 773.347788986097 748.973408369405 904.204319521099 906.636056340635 +PTPA 28.256037869826 26.6249263447858 20.2757908874437 18.0728239564515 +SHOC2 7.72997544907354 7.74333446521108 6.90601618254973 7.98426373765273 +RPL10A 522.435543139268 485.667659145404 492.392611968451 510.423563587747 +RAD50 12.1515461178286 13.5987186088796 11.604214802404 11.419333913626 +SEPT9 23.8445875138851 25.9384052954329 28.9034309167917 28.239835798779 +PIP4P1 17.1530623159801 19.1993172614631 14.9176795058588 14.7975438366885 +USP8 15.4462306923223 14.1934080648246 15.8724871889126 14.9949455448346 +DDO 17.8797607835355 16.1935843082903 26.6348953200209 26.1806956326395 +USP4 19.548088680021 19.7445325801515 20.632171543 20.9563345101626 +USP7 28.3623272704575 27.089124169129 28.5386368266807 29.0038501805952 +RPRD1A 12.0898313043201 11.2919214359657 12.8565394528293 11.7897425704543 +MRPS15 39.7765439301264 38.7061018068351 32.5303397443051 30.9860114392826 +NUP37 6.62269236902968 8.55106219268845 6.32501106676224 6.31758246956136 +RNF31 6.79839887411567 5.57635056251201 7.27506283924423 7.07014171330764 +COQ4 60.5799369561079 43.8075052818941 45.320432552808 49.8090101563264 +ASAH1 27.9087036641586 26.9879316403361 35.1164952455482 37.4533020880166 +TPPP 2.39299626474782 1.82283540051573 2.75620140895303 3.44847635653991 +XRCC5 15.6485511994452 13.9718291334595 15.1655900119787 15.9896674277136 +BID 37.3859512843894 32.9671925958621 25.8943289715174 28.2021718354112 +PHKB 8.56482569309427 10.5995124487326 10.2142947386925 10.0748111444923 +PFKM 5.60888423279579 6.4051362199881 4.32066165415171 5.6883104843771 +PFKL 21.4230805741696 18.7286650960549 18.8488375870551 18.7033259828236 +QDPR 159.595034886458 165.936554688623 210.026785267431 197.643457678111 +PITPNB 360.197810539502 192.077860463449 95.1092192697193 163.346336795645 +LMAN2L 9.5978092676667 10.7695965051459 11.9448316939418 10.9779862378644 +TTPA 96.0018825795778 93.0917839838836 145.197288750906 162.198741051839 +SND1 43.3242585859928 42.7707389667076 35.0644793778645 36.6582438976897 +TPP1 48.2436772293794 46.3102887603243 64.7038843464638 63.2855907619374 +TPP2 21.083060107582 20.7940616594741 29.447964049677 30.9181053929673 +PSME2 84.4848305091922 83.7518316315257 104.812192128552 105.784399628393 +PSME3 33.1255727871373 35.0368805183914 41.3048457914079 37.3838819365836 +PSME1 121.686128454207 132.150969028841 144.315418677829 139.911282888582 +SRSF6 72.5125587375482 76.8721574654021 95.3146156423398 99.0768008814441 +CUL5 6.20011869437417 6.73595610836283 9.86683738611946 11.6787572668919 +SLK 5.151547952439 5.59545378396116 7.64222252739976 7.48745958689809 +CIDEB 245.85458838176 265.50657590743 183.907003807543 189.210949819046 +CTNNA1 60.3441432893955 56.7793055561829 58.9772839305747 59.0281950481608 +CTNNA2 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +PHYH 688.197844648476 721.803069405695 685.556338516354 688.712626200585 +TAMM41 8.95712938690098 8.67804745613034 6.99601856921458 6.85837380069178 +ABCF1 28.7085241890514 24.1187376610861 18.6524429164111 18.3085876976027 +TOPBP1 17.1793181676845 21.0126963732721 23.1189318405407 24.2478519343311 +CLEC4G 61.9377624554668 53.2093915875917 96.1115237269783 89.6005231604668 +GSPT1 24.1310809357523 29.4231812675696 24.8407601923392 25.311640156315 +SSR1 83.7516509397398 88.9138235038488 81.8350778924123 85.2523835276486 +SSR4 350.327953408153 369.330116755055 206.941504772693 209.812679638859 +TMEM33 32.5245965323839 23.5141309115442 35.0613943221621 33.1097323120709 +CNTRL 7.58232392639251 8.01163562613705 9.41977996803191 10.1026539081406 +SLF1 0.793706032786175 1.91075453452366 2.39083577551986 2.43203359279064 +GDA 10.7350384370192 12.9520393613239 29.4950242948124 29.1451052215487 +TM7SF2 291.542004398717 278.5850612102 184.68624125316 189.814845222148 +ADPGK 7.97956529400927 7.06799467629055 8.39975070366237 8.32851601229047 +MLEC 37.4439121045691 28.8282035412446 35.758198949652 38.077523926832 +TGM2 10.3486285771429 11.4691927760261 19.5615759072075 17.6685007483509 +BGN 60.8353824433538 57.2317328238854 78.2696470771189 74.0297208132895 +CASTOR1 48.3036674623801 44.6669702410799 55.6548796040919 54.9001456817541 +IST1 31.5457898288152 33.1486548966724 34.6837930766505 38.0501348177057 +RAPGEF1 9.12187604489521 9.41786025440413 10.396339747392 11.0048352699071 +XDH 101.202048553012 96.5856328516855 155.316130552726 157.500913001808 +ASPDH 41.5592999592046 41.9269320968054 54.1833574946159 53.9632948153111 +SELENBP1 128.386976648313 131.661185535214 195.671527818047 193.262850530665 +PARK7 196.853883832298 211.01053449687 162.970790243819 168.437443284478 +PRODH2 17.6677859326269 14.9494791902283 24.8993412860327 22.603299913956 +RORC 27.1935096584622 20.973430735189 41.5418266844208 44.6572302886651 +MPP6 9.58481720981553 10.3334615505221 14.7132789309543 13.5833340367894 +EML4 11.6499635840458 11.8791888907856 9.14166578133903 9.66746941437033 +TFRC 32.1588616445542 35.080431918295 42.9903352904979 46.4564554131505 +NSFL1C 51.6797449191978 52.1959665825351 41.9422603705059 42.264780093323 +TAGLN2 158.890476308302 154.304972363477 116.970370421136 121.106719813514 +GUSB 99.5492052096389 89.4623052117609 76.3183345014787 80.0881703157777 +GNPDA1 11.428761876332 11.6264805501862 12.0915474392299 11.8813927210383 +PRPSAP1 27.8178319082472 29.2300797841848 28.2243651101374 28.4827826845491 +LAS1L 28.6258394401495 27.4995813130676 34.2167274444323 33.3578597312871 +ENSBTAG00000040134 -0.0831700079418282 0.336369597315913 0.00134137986675392 0.189229847923004 +PRUNE1 9.18541976886155 9.95036218710292 11.3014639186498 11.2688865440148 +ETFDH 177.037886409563 183.249164696893 145.09781309468 140.832778307184 +SLC25A22 73.9589834419167 68.1724070317227 56.7679363918833 56.7843668062858 +SLC25A20 151.949348366397 142.263863061675 86.8355497020626 85.1757049610774 +ERO1A 9.25440324239461 7.3225526684309 12.0191688060105 11.7732032924544 +CFAP73 0.743363872833968 0.706085352634496 0.300861576029231 0.573142127924048 +SLC3A2 19.7087371039318 20.0718065454623 23.4094532069304 24.4615595221243 +GMPS 29.870982779832 26.7842642045823 26.0516225689546 23.7226373030927 +ENSBTAG00000030384 79.0572387982053 71.8003511502559 75.6411791013714 73.9175523889606 +IKBKB 9.39016871612226 6.42242499099261 9.63838428072726 10.0611783917461 +ATIC 46.0349639719812 41.8548056760177 48.3398152489513 46.7710974149198 +PCTP 166.359642145566 175.083299327738 292.220188583063 299.035809396551 +DHODH 10.1097257817121 29.8612453253894 53.743038156052 44.6535957158876 +ENSBTAG00000046905 294.961776845781 316.75190956572 676.812014673574 734.016393422132 +KPNA6 9.0766959981535 12.0452530588078 14.0199272555947 12.1435781793676 +REXO2 36.3754494468237 37.7208812987856 21.1090331856531 21.7792875522784 +KPNA3 11.6103727488303 12.8328785193649 15.1446676650183 11.3258290429304 +KPNA2 42.5590721305159 45.3785958412507 18.9699240936851 16.8276982964737 +COPB1 47.244652891335 48.7787065596453 45.5610876461587 43.2938003810097 +COPB2 56.7510312632977 59.8038348970272 58.9128676570453 58.4246096983358 +SEL1L 31.3911439801136 30.4874984327682 31.1533109386842 32.2169833706533 +UBE2N 15.7642475622484 18.0733111679771 18.5099683032222 17.8977958130858 +PTPMT1 15.1607116144756 22.5423568368952 9.51453227417887 10.1339818732223 +CRP 666.499088478238 713.541380069835 918.464034661118 906.318178318667 +PLCB1 5.60761456184079 6.00617402612108 8.45444961191414 10.7072765385123 +GORASP2 37.7853181123845 39.0989085134489 39.8021068170872 38.5903525584881 +CARM1 17.2473328256999 17.3610882896556 16.1464690736533 17.9103193908918 +CIAO1 29.7027226805061 31.7538104234952 33.6300821380498 33.1084546098582 +EXOC3L2 15.169530072097 11.5274532597491 12.1798066972612 11.9123200038719 +TMEM177 6.07076994331966 5.4817776815275 4.78095805328256 5.94455991314799 +CRK 28.5760679042961 33.5829530236427 33.8183896098916 36.2494518973819 +EIF5B 18.9574933256212 20.4594532930094 20.2194234505784 19.3886813783932 +NUDT21 13.3898160327846 13.7235935671389 15.8981120108481 15.7039419160264 +EIF5A 165.113608928114 150.057884441389 129.893386160744 134.418586456986 +SUMF2 11.613044248213 10.7428645877262 8.42972029406572 9.10567688491536 +NONO 101.851637823195 103.649731252405 107.904758178213 111.532225062065 +GLDC 59.209549767086 61.1548259100042 61.0569597311577 64.9902748044089 +UNC45A 12.7898362153029 10.2699815457568 9.14453674910732 9.50090834141673 +PC 226.403337366722 207.408392938572 102.763171115844 96.6632336944888 +RTN4IP1 12.1087558944506 12.3114932628181 10.2911697995303 12.1320256104594 +FNDC3A 26.3585435690512 28.5703264957545 34.402696454005 32.8930759898736 +PGK1 95.7840568382875 108.534277983341 75.0372085818883 73.7897244606472 +SULT1C4 291.430011694031 300.024996696624 440.225300844514 422.914030258642 +TUBB6 22.7059237946646 23.2839080788028 13.5079610898157 15.2799731941493 +DHRS11 52.6333820746664 46.4521446062941 30.6731140620596 27.4075045026436 +DHRS12 33.3739529991199 31.3040649093136 41.4674536590385 42.6154586080277 +ACSF3 6.11324553660114 6.52961216294506 7.86146182187559 6.7635716515776 +TUBB3 -0.0774162884737161 0.134034142258097 -0.0046653135275288 0.0876038443049007 +MAN2A1 54.8985492426166 57.0662157202894 61.5936799889028 56.6424365310961 +RPP25L 14.8985978021657 12.0865287859421 11.1641128816336 12.488246056597 +EEF1D 69.578507609549 65.6057500444713 81.5820514564535 79.4905832947988 +SPACA6 0.361573709714022 0.753604635373241 0.978151330632951 2.03827098270122 +GALK1 86.0722710369343 69.3343456711129 68.8171052003845 67.6043755797367 +SH3BGRL3 77.4599927428386 68.3687856822019 93.0551007514801 93.0099697015296 +RPAP1 7.57181758211171 6.57530826304162 5.90514325875072 6.42612515709546 +PRPF19 22.3678715758988 22.7189678577124 22.5218620446562 24.424173415435 +EIF3A 27.1023132321997 25.0313766356453 31.1330275501081 30.9017362415226 +GPD1L 1.57753639655264 2.56191737328948 2.08968319990665 2.89492795660087 +TMLHE 23.905666665915 29.1206372934861 32.796672666397 32.6729224123944 +EIF3B 24.9111665983165 24.660577468471 22.5286637437112 24.2577135567484 +OXA1L 57.3687297631895 52.6429049324472 50.9569901574072 57.3157898007743 +TINAGL1 26.8795714489404 24.9035932894017 18.7854935786453 19.2171353912864 +EIF3E 125.461055182154 140.366120904336 190.522828499359 201.652579842078 +DDC 78.0045646123552 73.5663279823455 56.3898300438292 54.78775350057 +DARS2 8.62937951535084 11.0172857388289 10.9486104386152 11.5994134749835 +RHOT1 9.20073878048794 7.91958000084078 9.30065941712892 9.27781525512538 +ARHGEF1 17.3006014247564 13.5106982766885 13.9487459721145 14.0989463908364 +TP53RK 16.6366476835055 13.7410449567384 15.6367839647921 15.5914477705035 +DNAAF5 2.87768430008665 4.0390439686093 5.23365719219573 4.60014227389485 +POFUT1 14.9784842114819 13.3895714353838 17.3626512199973 14.4667677713188 +STAT6 23.9652450416285 22.9495038451976 32.7175417815338 35.4333163013375 +LAMC1 8.29891786443087 9.27088104888158 8.41521943666484 8.90698680093423 +STAT3 61.8989986629068 62.9659633281389 66.064065393003 63.9660589328523 +STAT2 76.7001680799094 76.4820989909521 53.8704564013336 51.8834507998727 +STAT1 42.3491602526059 44.9403697501803 68.1561309804726 70.320208677919 +CD81 739.195338158362 597.149674912367 785.87986757652 988.73054984824 +ENSBTAG00000037605 112.193515718346 137.455314593375 220.373219966353 222.860096356454 +HPRT1 145.568966743949 139.590835205449 100.974238442668 106.245572789108 +USP19 10.1451441989918 8.83798777996237 10.2671576324857 9.21874454811124 +RPL13A 902.270875008053 855.77939294108 845.415841972656 831.460338493162 +ICAM1 18.5497374712207 20.106848125997 33.4743674214867 33.0954528579065 +CYP7A1 353.321091628517 360.732534452581 114.483237046987 109.379648058528 +CTDSP1 70.9515501890435 57.7823385456826 68.8600005097348 67.386575594568 +DPM1 46.6851838785596 54.3514290186536 61.396419348481 55.7110522780492 +CRYAB 71.2732915801441 64.3750079426704 34.3916038139006 33.1831103407203 +CD68 58.4412491081966 49.2080951615777 99.2358600942641 106.748736064321 +LMNB1 15.4747140613834 16.9248713718601 10.4944202917585 10.3333802981208 +TPD52L2 35.612778578019 33.6052679629902 35.5664908076217 33.950384744388 +MAIP1 16.6308546789095 23.0257225615989 22.7599012933488 22.5482155845606 +EFCAB11 17.126756551107 14.9636598506989 22.5598287168025 23.6153844427344 +AKR1B1 2.96375102454787 4.46447000733232 4.89548897048109 3.40284756391362 +LRBA 8.30205171774549 8.72658812144922 11.8142644146812 11.819947610821 +ENSBTAG00000037510 5.26791630363935 7.26875706005174 7.07208349675611 5.29304238219484 +SLBP2 0.106153018018065 0.264099615389296 0.000138702752987413 0.0124688082336339 +LRP1 75.664005908009 69.4989414331151 82.8018780142199 81.7905462001151 +GSTT1 237.940867116054 219.400278113134 212.564614939351 217.902195332073 +ISOC1 57.8055086852417 55.1754239477193 55.6141451623398 55.1416221830048 +ARPC5L 19.5132338601515 15.467451509124 14.1333202795052 12.0379447589528 +WDR13 17.747915895399 18.6134887223395 15.2689697860508 14.7304825059729 +ATP5PD 220.742913291364 230.031113412964 244.166210542019 225.905011471236 +WDR11 8.09155991029668 9.41917575128198 10.4762363940287 10.4754154133098 +TMTC3 3.60787174427426 4.73734363088774 6.07391287312021 5.19723259731821 +RHEB 64.0377060954215 74.667273342106 64.7727182132688 62.6735842421473 +STIM1 25.3824996003576 23.7695724187523 25.6999653636141 25.8769077652717 +CD276 8.82032610485212 7.41487489874305 9.02341643473609 8.0282668971264 +CREG1 319.913072806807 342.737947415642 447.198175714106 451.535394080552 +CDH17 28.5365228158618 32.1691518265585 17.3929071029114 17.5374991235819 +SPATA20 17.7694446196313 17.388960771261 40.0605742230842 40.4864088105704 +ENSBTAG00000016472 49.944069185075 53.2102174001564 292.459596135763 295.866784432293 +C8A 660.431655902735 672.394521678753 732.850192149645 749.458762514293 +USP9X 23.5800586344973 22.6792434495969 28.5871394071642 28.3273863574209 +GPD1 385.25847634567 378.051617290156 348.306883504822 350.358539264415 +MAP2K6 16.0281244996811 15.7388029790943 7.31155159786695 6.76733220905233 +MAP4 19.7915529433612 19.2116980169171 18.7842481319334 19.9511808356765 +MAP2K4 11.1418565084672 9.77476642791027 9.08703817175683 9.44286636060874 +AACS 2.19053961099219 2.07198490149911 0.821257319530993 0.455875759333 +BCL9L 12.6531228241893 11.491654839831 9.41276916266325 10.6598752288268 +MICU1 22.8984165712335 24.6844200563809 31.4418207167772 29.6078526438213 +TSNAX 13.8695786853758 15.676846328741 13.9183310652625 14.5071776485395 +ENSBTAG00000048135 484.08402799493 454.406002270589 97.4853388800538 100.646252762607 +COX2 9776.28662387725 10716.4991954506 8751.58317732455 8479.36559492404 +GAT 401.62997318607 423.149952043416 441.610012386421 446.459804749416 +MRPL18 25.6051872027575 22.0999961720271 21.2252320409981 20.6800655801328 +PPL 31.1207848637298 28.5060886639143 39.4604125743003 38.4788179418618 +APEX1 43.6918009182472 44.0686703934567 39.0362761536603 37.8022969634495 +ACY1 230.444065173502 222.593854790853 179.292840806379 173.323525673474 +KMT2C 4.91417040642701 4.92766099299135 4.94129973818734 5.2367188120538 +ITPA 20.768905538505 19.9142236859471 22.8120202685552 24.5599059443441 +HSPB1 489.133661145212 415.116092053553 355.908666527239 350.424603569664 +COL18A1 368.410583739019 341.871565459342 335.35403262039 331.354947812265 +CYP4V2 118.354003243845 132.875626717481 227.005039091725 226.84690511476 +PKN2 6.3404605649041 7.71163916198982 7.66757154376476 7.26155683733302 +SUCLG2 178.467666307121 185.538233568009 226.481912503341 224.852913184971 +SUCLG1 164.27042014621 164.596661767684 127.774652520488 126.431615365527 +ENSBTAG00000021368 4.02647067972565 4.43576670363921 1.55075729199277 2.24777849393959 +DYNC1H1 14.8380364259534 15.0025050843806 14.831443481482 14.105847481682 +ALDOA 124.976277936463 122.115887345838 65.2538414399272 66.9595360243201 +ALDOC 4.09829216945825 3.45523596146609 2.48177584667866 2.75464571638655 +ALDOB 3451.90776091453 3546.12972279887 1979.31638044482 1914.85839471516 +ENSBTAG00000019437 47.7443042926225 48.3152315271311 41.1169251165603 42.0364073161225 +ENSBTAG00000046325 3.8208399238172 4.59262319997735 4.83410506090175 4.04830802282109 +DIS3L2 2.83293057424975 3.89743145626384 3.73102802913594 3.23118022242156 +IMPA1 24.6822018888113 23.8100815639814 27.057580761204 26.1623913468736 +RAB30 7.07106445705635 6.46314624791659 5.70432488243445 5.69878596878778 +CYC1 112.436460698199 108.092615132495 64.2569995060522 54.6438213670735 +PON3 264.193717996869 284.964469147879 269.861385932438 274.686204416286 +PON2 59.3201963557475 59.5414483864432 61.7998000773936 60.3229675775943 +PSAT1 152.962937954097 151.777981630948 184.717686117615 188.459215374667 +CPNE3 9.7660026324823 9.90645535258755 15.4505012938512 15.7469105440157 +SPATA2L 4.42717641069718 3.73896054611666 2.82437087437354 2.35173687687219 +CMPK1 66.1636180044806 71.6022588490059 57.7685604645898 53.4854742296461 +HAO1 167.717894978793 160.824591236098 221.358065607454 220.443974209934 +HAO2 187.570971207434 192.025263050411 217.73488876678 214.079960086085 +CMPK2 21.230764301077 18.5762519428301 13.1526928719043 13.3668648633129 +CKAP4 18.7830557856904 17.71858363054 7.28144193655506 7.51224663588441 +EDEM3 9.08769992752261 7.87997696483823 10.2331009426204 9.96834354700514 +FAM213A 63.9696715193459 69.1517156474714 64.4878177119997 66.9365763877794 +GSS 18.9762968394914 18.975843589736 17.5396854579566 16.9979794386655 +GSR 69.2279969734355 69.0235988893484 39.3070839941253 42.0016994981447 +MRPL2 27.3686782377983 28.4758532048872 20.6787950348944 22.6522920667887 +LRPPRC 22.0277996435072 23.6862121519368 27.0438859386522 26.0147568447486 +WASHC5 14.428682492683 17.0896216732749 18.2083006603826 18.5552956019669 +PSMF1 58.4792220928866 54.3311168378969 46.082326968347 44.6353958958178 +PPCDC 16.3661652954611 15.7154079524201 14.4690673271796 12.8918609618256 +AFG3L2 29.7850318291668 28.4001775235546 25.0939970188247 24.9823882942254 +SCO2 10.0480300837977 7.43570421484117 5.62520830383061 5.84375970842581 +SCO1 24.6768359721274 27.2357998822851 25.4907485518165 24.6718904085099 +PBXIP1 26.5678841420868 25.780478902187 25.6353053086839 26.2621257671262 +UGP2 153.807479279161 167.450212271263 252.653407540392 250.892054052141 +HTATIP2 34.5750045019044 34.0791057099677 30.9804714631501 28.6460455781294 +MPST 29.0434347800226 29.6747730019902 24.5852404783233 21.526554983884 +KHK 424.121411542236 398.069851329902 287.711845022062 292.533955886127 +GOLGA5 16.9202116093515 17.1192207392601 16.5383232238207 18.728334914904 +APEH 63.0107623468651 57.1381037083468 52.9024329834931 55.4252409883236 +PTBP2 3.50437045388712 5.120321480847 5.11516862693669 3.8134774564304 +PTBP1 61.792106851724 56.9526504026376 62.5532858623853 90.5634456823494 +NNT 66.5612758120302 68.6387452544516 91.9591221488936 96.2019540925283 +ENSBTAG00000038461 145.170397917537 155.484049359575 331.569435711984 331.125799942062 +BOLA 334.1357501053 328.451874726353 347.761913356719 351.445738758055 +ENPP6 1.11352833752061 2.15750699392109 3.4183815308323 4.68374824425309 +HK3 1.96777435315938 1.90947590090858 4.43719896841559 4.34478955205684 +HK1 4.51687993326148 4.43622454982727 5.56933367307585 5.23941824766038 +ENPP1 41.6851256811112 42.8457198983143 69.1907361126924 69.5436530272398 +ENSBTAG00000015438 100.328016118494 91.3980026147465 96.5294691534659 93.6546580362091 +GIPC1 11.4277160848065 11.2773021623264 7.96787002548607 8.69118025216987 +MGC152010 527.247902239854 574.719200908395 859.523104420852 856.862759415067 +CSNK2A1 32.4656455354029 31.8142249423965 35.5107331221583 28.974282542234 +KCTD12 7.8759719298296 9.57184068445817 13.4443681453086 12.9261000270817 +MTCH1 71.6014500318977 67.6970157452901 65.3928229570774 61.7590442620856 +ENSBTAG00000001700 96.709309734878 89.3699825419507 127.489149037838 108.715602572932 +MSRA 198.979208792047 217.660540394948 280.194783446184 266.897301418176 +PPIP5K1 3.16771452170751 3.5071360385884 3.23464110022609 2.96175755469464 +ALDH1L2 17.7070197203968 18.279888142472 20.1158306692226 21.0386507848915 +DHDH 0.0581083664627774 1.06266070693223 0.659910471638891 1.62193107520772 +CPS1 1015.03495063784 1059.86766480298 1041.36139659889 1031.34079350451 +TJP3 5.33849093420849 5.94831687438961 4.28106682647141 4.19657247884915 +PLS1 12.3824735501403 11.7047922786731 16.3321758966762 17.119207733288 +PABPC1 157.175590202279 165.887868423322 201.975619550826 200.237891039401 +MACF1 10.4860303733842 11.3407338436167 12.1061646889973 11.8755609619116 +PABPC4 37.0073640188839 36.0643267010883 39.0770837735542 35.9400903011878 +H6PD 25.1824525631432 22.0817055358498 34.6497571369148 33.7804786627786 +CHCHD10 436.556921342311 386.527804386428 329.742261695376 314.466096102487 +GRHPR 140.340147500654 133.364427480606 105.373264063931 108.518650008552 +JSP.1 145.406970348444 130.858672903965 162.275328129491 162.649185902303 +DLAT 9.76486274713574 10.0629384608034 10.252222535635 9.8843259031543 +DNM2 22.6381125407442 20.7047151059998 16.8311293711382 16.9572373751209 +DLGAP5 6.94168320497557 7.00679498784597 2.15170361399677 2.25614640502072 +ADPRH 19.0551036954799 21.6633529080608 20.5196433017802 17.3422729463392 +PDHX 9.87198721613451 9.51152293393627 9.38879915168634 8.36734675092298 +C14H8orf33 6.35155588580121 8.95547696523315 5.36175740785933 6.67839143560736 +TRAP1 21.7633894261898 23.2278802326696 18.0120618706945 17.386040627109 +TRABD 41.5119353517831 40.0943537624348 34.0813877205476 34.2955447657234 +GOLPH3 17.3684332128233 18.1370240728292 18.1409333709834 19.6663049547591 +TUBA1D 2.86316992433849 1.98730260289615 0.991472233976692 0.913767360463091 +ARHGEF37 7.64007537466363 9.05655908795872 7.62489155376112 6.66173528565187 +PIK3R4 13.1027470315307 13.1144889000207 14.8492296616698 15.0618860483517 +PIK3R1 20.9302465344734 24.2368400106678 36.9054017519066 38.2380072593127 +PDHB 63.5985433226674 66.0883293891273 60.4632956869974 59.4235674015974 +OS9 190.626531539601 182.701322081904 230.402995583996 228.470274325779 +GYS1 3.45956558132797 3.22906260841617 3.31761088335026 2.91412568764841 +DSTN 118.017543387822 120.249289252258 135.970132888052 129.526156270366 +GYS2 88.501114834891 89.9220101938546 84.2792287498104 82.2392986396327 +PCBD1 303.778815408818 317.373047853574 339.076481249434 342.729239412448 +ENSBTAG00000047868 14.9011726827145 12.5492108373937 21.3059699074118 17.9134496589239 +ASMTL 43.2900545606576 39.8325034971835 34.06063474181 32.9999292710297 +AP1G1 23.4928976107536 23.5122367599228 32.7676734811657 36.2840255893495 +G6PD 9.74110175474349 9.15443642207596 10.1947423250947 10.6922396771276 +HMOX1 94.5345658311689 96.076458768341 166.025857888372 166.032163636329 +USP10 18.7755663923175 20.9416310777884 14.5605539662602 15.1311878428841 +HMOX2 51.6287102313384 49.0590585279345 38.8904436352197 35.2987847703607 +ELMO3 12.7956638592499 10.4710270918202 11.0742755464958 9.83727506578679 +AASDHPPT 19.1879741963346 22.050346679325 23.0291238356126 26.279569987493 +GATD1 17.6557301095478 15.4078952909406 12.2362333131729 12.135342251792 +SULT1B1 48.8751080416642 45.2436347257541 44.8067473580682 44.5275669504281 +TUBA8 17.5722077879855 14.9056682186825 16.3827711052815 14.8464311057785 +RAD23B 73.4193674995929 87.1377296427218 84.6984455407686 80.1680277260265 +EHD2 2.77838489510825 3.04260351258535 2.49681188702543 2.2820198577997 +EHD1 50.7645636676094 42.9372494912876 37.4893545874391 38.6283774117773 +ZER1 11.380113364983 9.67183182579823 10.8337487205005 10.2754819426689 +RPS18 1224.55008039431 1153.92892777079 1015.20806121192 1031.59513195139 +IYD 79.0421074773175 75.7748146805289 88.7538559412406 84.1982245267858 +STOM 123.375413201999 130.062763337908 180.747148384111 186.988817825313 +RBKS 20.9812744565393 22.4174383324462 14.2981464468043 16.0419242278195 +NPLOC4 20.2069825431381 19.4790287213838 17.9196243898731 19.3632395568121 +IDE 15.3826661274661 15.6786108042442 18.502163960468 19.0154116845995 +MBLAC2 2.93422751402475 3.11833731302927 4.43548152868138 3.61392008928895 +ENSBTAG00000038171 196.268578645567 207.760567600323 241.621757337222 240.881711567728 +FAHD2A 87.8083042829723 78.2576003419607 74.0486493085067 76.6994031747348 +TMED4 46.6040708253926 49.970480253914 39.3924497379826 41.1908906015733 +SNX5 58.0632176766377 64.2645769326113 69.3322021508398 71.2390044330657 +TMED1 21.1550574429793 17.9316183062525 19.2845642083999 15.3684430580934 +CGN 36.4595414913225 32.0950532381475 28.5328117882117 30.32415344131 +HNRNPR 39.6074077331533 40.6374907810351 38.7997986169393 39.81730375341 +ENSBTAG00000035584 12.2770721103672 13.6590283399985 13.1723897904586 14.5969677517862 +TMED9 124.546993815518 122.23059002418 105.468276523977 106.489434562028 +AP2M1 123.897418750213 117.027371680683 111.379756213687 107.518606639905 +HNRNPK 216.438371119715 210.869716421668 219.486206150716 215.818466293076 +HNRNPL 63.0577494611125 62.4953862674554 63.5605075649486 63.8489052278032 +HNRNPM 81.4352431238127 80.2727854827795 64.8668230991941 64.0386505254954 +PML 6.40740861999599 3.74233508171709 4.64471418122886 4.9399741753774 +HNRNPC 83.1127894198936 87.7399828792461 91.5373073681659 95.2423540512587 +HNRNPD 65.1874119065708 67.9524196027318 67.9990778723265 69.3000376964631 +RPL27A 1110.60736878681 1141.59599801037 1079.30175588219 1100.68639698477 +HNRNPF 188.635171730018 198.121645510779 236.716997853245 236.723021834018 +TMEM205 184.489398561876 174.382840841176 180.882975921995 178.962536988835 +FMO1 663.957629180915 701.06736922803 980.878173975301 979.502184481915 +ENSBTAG00000038549 108.747288945721 99.9133579846071 107.666944235911 110.615632930359 +RCC2 12.700862348812 10.5340919790125 9.70386747308079 8.69050885707611 +PBLD 55.2597272119143 56.1092389554101 66.6264020139609 63.3892449572176 +EEF1B2 391.881152100155 409.230484090909 434.488618287884 458.741411147348 +ERP44 86.621974076124 87.4279702127664 87.2204247605244 87.1048737950272 +GCAT 96.8297751911387 95.783827835909 94.1867552227682 97.4489230250513 +STAU1 36.7173904932472 40.4759046716152 41.407438398495 39.3263328220922 +FAAH 86.5698629893087 79.852719894669 70.6273918181793 76.8793186709116 +VPS26C 6.00710611891897 6.46867816243839 5.7513743141297 6.507044092946 +PSPH 16.854154708231 16.0251137708093 7.7486597488712 6.35833523027556 +UGT1A1 684.188701174059 693.882804307321 640.149009955714 639.535572756478 +ENSBTAG00000002943 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +PGPEP1 47.2686906102461 49.8973593856128 49.4809856408309 48.8566214838105 +GLUD1 656.110818700157 667.614033257216 643.845919696242 625.83289405332 +ENSBTAG00000037613 450.803459117423 485.334795333524 458.480418159638 460.051420106146 +TIMM29 6.73378809403034 4.61606265009626 5.61971147526111 5.61103274347862 +HSP90AA1 264.959876171417 281.737117804499 211.559533011189 204.419349845353 +TIMM23 48.2276937250432 49.5477610413749 38.2010716471407 39.5516764220633 +TIMM22 2.9779359455591 5.03513830922428 4.57766504719711 3.69019224325445 +TIMM21 22.9633660509231 25.5427128457841 22.9471924440751 22.7741109146881 +KARS 54.2791009534698 52.7908967916207 67.7231516102737 67.5815708119999 +HP1BP3 29.3421095840681 31.39238753324 33.7829527675812 32.7847645169075 +NDUFS8 85.4156300221413 91.7853322351507 65.392093459396 61.6781463892882 +CYP2D14 231.360921414891 224.485267054532 456.577628032366 448.65397703679 +TXNDC11 51.6403424117011 51.0785155914478 36.8772113020138 37.7219423903237 +CD58 22.8671692478851 25.164892363039 25.7169492114737 24.1581392883673 +SCP2 749.564202612591 777.679865805852 932.056096360398 939.928108070764 +MSN 14.8468265774399 18.6138096199231 21.6626739228865 21.3568084413381 +ZNF326 17.7799256975569 15.6250344604187 18.3714769148998 18.8137140847393 +CACYBP 65.8511268882502 67.8944752372627 52.7753585597001 60.9440250551207 +PDE2A 12.1014198230228 10.126228483765 12.4896304121948 9.95500686142616 +OPLAH 11.7527157254726 9.82513795202479 5.45271711808034 6.05224514488442 +SEC31A 55.4599343957457 58.5404301901295 58.8760181715344 60.7197082614718 +PRRC1 34.7463089404113 32.2595374347583 27.6716014035645 30.7583958831148 +RAB35 7.82839916809587 8.0124938651858 8.0771538438553 8.58774636109239 +SRP54 26.9210223365744 31.7450878893208 31.7787240409449 31.42668406125 +RAB32 142.550735319666 134.51170785237 117.39958831372 115.689748377378 +CAND1 12.6044607008631 14.5021655863634 15.2072452439481 14.6914434731307 +PRPS1 15.3347060001018 15.2261635475863 15.8085120424699 14.9796706811849 +DAO 50.3961515965993 41.4898908105392 77.8295602693701 77.9014073714062 +TATDN1 28.3902774962365 29.2063037345338 40.062345321928 38.8554011671924 +ENSBTAG00000037509 153.974244178864 168.577857027868 118.59223268085 119.688275843892 +RPIA 10.0411202069523 7.71295440633761 8.06876082077743 7.9312262952526 +TTLL12 26.3146835863755 23.400308321264 24.8959310699421 23.8929300367068 +LDHD 13.3865059324636 12.7769732843129 16.0981763399116 16.158255124931 +GMPR2 61.5603561075099 52.7488327338009 46.6696736465609 46.7349152524274 +LDHA 207.730032556293 226.891741973915 52.7798443855118 53.0922016798784 +LDHB 1213.63815105495 1294.32612194355 407.184967798351 410.717652900092 +LDHC 0.996700003910787 1.4243441795977 0.367575854627836 0.529836482163856 +LONP2 104.723442540721 106.230729202829 113.693254984474 116.563293627589 +PLS3 56.7198089183436 62.5935429696212 54.6704613566612 54.8233621601003 +LONP1 35.0285838875834 35.3617280286151 29.2954355019332 32.2547575935306 +PRPS1L1 -0.0758996600312405 0.135819323886117 -0.00624862361024775 0.00569716975406065 +PDIA6 237.078629510045 246.02532052621 161.475583919526 161.739154992676 +PDIA5 25.0597837080607 28.3971220939429 41.715172486751 39.338047316991 +PDIA4 211.873913148269 210.001936921539 145.23112104313 147.050443090863 +PDIA3 338.000109411079 361.355970968745 254.175745803677 263.613526088518 +GAPDHS 4.02245035382783 3.92129771588966 5.37370796946667 3.21280136749778 +CFL2 16.4395278148457 16.6215740674699 11.4464590162857 14.0380871787687 +CFL1 270.858978945402 277.97105818897 251.876578742101 259.003824894279 +PLAA 16.1144856376278 15.9790411228606 14.0881689734665 17.6164371479456 +BICD2 8.08825997009739 8.13016509366486 7.54569660889039 8.09658275324354 +SEC22B 28.0158406759932 26.2168927410539 25.8085478130071 26.2476955958624 +NFIA 18.7998060312645 20.6019630622779 25.8027529792118 24.0930147370757 +CD163 41.2947020425552 45.7036852574451 72.9594414051051 75.7918900293897 +AARS 34.2338462472451 28.8187366028439 28.2737262835897 29.253852156971 +PDCD6IP 47.5366726918095 49.4878158869482 49.3569707972503 51.6081599918002 +TSGA10 0.532544422811476 0.549561083730723 0.808442535970308 0.993907565460829 +DNM1L 10.9793186842086 11.8429623497427 10.0686886407995 10.7556465831498 +SERPINH1 15.3198304548624 15.9048127634568 8.28307047703207 9.71105820398736 +FOLR3 138.428905969161 116.281636988597 85.8755941382458 89.4439500612999 +C5orf51 17.2935605353597 15.0249063894766 19.5560379723125 22.1981123516811 +GSTK1 217.176269127719 211.304802899312 239.829423960609 229.9821520916