view pgSnp2gd_snp.xml @ 1:57c5ac41f22c draft default tip

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date Tue, 13 Oct 2015 12:27:32 -0400
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<tool id="pgSnp2gd_snp" name="pgSnp to gd_snp" hidden="false" version="1.0.0">
    <description>Convert from pgSnp to gd_snp</description>
    <command interpreter="perl">
<![CDATA[
#if $snptab.tab2 == "yes"
    #if $snptab.needRef.colsOnly == "addColsOnly"
        pgSnp2gd_snp.pl '$input1' -tab=${snptab.input2} -name=$indName -build=${input1.metadata.dbkey} -addColsOnly -chr=${input1.metadata.chromCol} > '$out_file1'
    #else
        pgSnp2gd_snp.pl '$input1' -tab=${snptab.input2} -name=$indName -build=${input1.metadata.dbkey} -ref=${snptab.needRef.ref} -chr=${input1.metadata.chromCol} > '$out_file1'
    #end if
#else
    pgSnp2gd_snp.pl '$input1' -name=$indName -build=${input1.metadata.dbkey} -ref=${snptab.ref} -chr=${input1.metadata.chromCol} > '$out_file1'
#end if
]]>
    </command>
    <inputs>
        <param format="tab" name="input1" type="data" label="pgSnp dataset" />
        <conditional name="snptab">
            <param name="tab2" type="select" label="Append to gd_snp dataset in history">
                <option value="yes">yes</option>
                <option value="no" selected="true">no</option>
            </param>
            <when value="yes">
                <param format="gd_snp" name="input2" type="data" label="gd_snp dataset" />
                <conditional name="needRef">
                    <param name="colsOnly" type="select" label="Skip new SNPs">
                        <option value="no" selected="true">no</option>
                        <option value="addColsOnly">yes</option>
                    </param>
                    <when value="no">
                        <param name="ref" type="data_column" data_ref="input1" label="Column with reference allele" />
                    </when>
                    <when value="addColsOnly" />
                </conditional>
            </when>
            <when value="no">
                <param name="ref" type="data_column" data_ref="input1" label="Column with reference allele" />
            </when>
        </conditional>
        <param name="indName" type="text" label="Label for new individual/group" value="na" />
    </inputs>
    <outputs>
        <data format="gd_snp" name="out_file1" />
    </outputs>
    <tests>
        <test>
            <param name="input1" value="pgSnpTest.ref.txt" ftype="interval" dbkey="hg19" />
            <param name="tab2" value="no" />
            <param name="ref" value="8" />
            <param name="indName" value="na" />
            <output name="output" file="pgSnp2snp_output.txt" />
        </test>
    </tests>

    <help>
**Dataset formats**

The input dataset is of Galaxy datatype interval_, with the additional columns
required for pgSnp_ format.
Any further columns beyond those defined for pgSnp will be ignored.
The output dataset is a gd_snp_ table.  (`Dataset missing?`_)

.. _interval: ./static/formatHelp.html#interval
.. _pgSnp: ./static/formatHelp.html#pgSnp
.. _gd_snp: ./static/formatHelp.html#gd_snp
.. _Dataset missing?: ./static/formatHelp.html

-----

**What it does**

This tool converts a pgSnp dataset to gd_snp format, either starting a new
dataset or appending to an old one.  When appending,
if any new SNPs appear only in the pgSnp file they can either be skipped entirely, or
backfilled with "-1" (meaning "unknown") for previous individuals/groups in the
input gd_snp dataset.
If any new SNPs are being added (either by creating a new table or by backfilling),
then an extra column with the reference allele must be supplied in the pgSnp dataset,
as shown in the example below.

-----

**Example**

- input pgSnp file, with reference allele added::

   chr1    1888681  1888682  C/T     2       4,3     0.8893,0.8453   T
   chr1    3118325  3118326  T       1       8       0.8796          C
   chr1    3211457  3211458  A/C     2       17,10   0.8610,0.8576   A
   etc.

- gd_snp output::

   chr1    1888681   T       C      -1      3       4       1     0.8893
   chr1    3118325   C       T      -1      0       8       0     0.8796
   chr1    3211457   A       C      -1      17      10      1     0.8576
   etc.
    </help>
</tool>