Mercurial > repos > bgruening > hicexplorer_hicsummatrices
annotate hicSumMatrices.xml @ 15:f5d54dc64697 draft
"planemo upload for repository https://github.com/maxplanck-ie/HiCExplorer/tree/master/galaxy/wrapper/ commit 91a0182476a7fc26be7bef1677790518c4e88348-dirty"
author | bgruening |
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date | Mon, 16 Dec 2019 13:12:48 +0000 |
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1 <tool id="hicexplorer_hicsummatrices" name="@BINARY@" version="@WRAPPER_VERSION@.0"> |
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2 <description>combine Hi-C matrices of the same size</description> |
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3 <macros> |
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4 <token name="@BINARY@">hicSumMatrices</token> |
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5 <import>macros.xml</import> |
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6 </macros> |
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7 <expand macro="requirements" /> |
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8 <command detect_errors="exit_code"><![CDATA[ |
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9 |
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10 #for $counter, $m in enumerate($matrix_h5_cooler_multiple): |
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11 ln -s '$m' ${counter}_matrix && |
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12 #end for |
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13 #set $m = '" "'.join([ '%s_matrix' % $counter for $counter, $matrix in enumerate($matrix_h5_cooler_multiple) ]) |
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14 |
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15 hicSumMatrices |
f5d54dc64697
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16 --matrices "$m" |
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17 --outFileName matrix.$outputFormat |
f5d54dc64697
"planemo upload for repository https://github.com/maxplanck-ie/HiCExplorer/tree/master/galaxy/wrapper/ commit 91a0182476a7fc26be7bef1677790518c4e88348-dirty"
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18 |
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19 && mv matrix.$outputFormat matrix |
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20 ]]> |
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21 </command> |
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22 <inputs> |
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23 <expand macro='matrix_h5_cooler_multiple_macro'/> |
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24 |
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25 <param name='outputFormat' type='select' label="Output file format"> |
f5d54dc64697
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26 <option value='h5'>HiCExplorer format</option> |
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27 <option value="cool">cool</option> |
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28 </param> |
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29 </inputs> |
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30 <outputs> |
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31 <data name="outFileName" from_work_dir="matrix" format="h5"> |
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32 <change_format> |
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33 <when input="outputFormat" value="cool" format="cool" /> |
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34 </change_format> |
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35 </data> |
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36 </outputs> |
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37 <tests> |
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38 <test> |
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39 <param name="matrix_h5_cooler_multiple" value="hicCorrectMatrix_result1.npz.h5,hicCorrectMatrix_result1.npz.h5"/> |
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40 <!-- <param name="matrices" value="hicCorrectMatrix_result1.npz.h5,hicCorrectMatrix_result1.npz.h5"/> --> |
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41 <param name='outputFormat' value='h5'/> |
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42 <output name="outFileName" file="hicSumMatrices_result1.npz.h5" ftype="h5" compare="sim_size" delta="70000"/> |
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43 </test> |
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44 </tests> |
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45 <help><![CDATA[ |
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46 Summation of matrices |
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47 ===================== |
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48 |
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49 **hicSumMatrix** is combining two (or more) contact matrices of the same size to one. |
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50 This is useful if replicates of an Hi-C experiment should be merged into one contact matrix to |
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51 increase the coverage of the data. With Hi-C, real contacts are sometimes difficult to be distinguished |
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52 from noise, especially with a low contact count. The more contacts are given, the more likely it is |
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53 that a high number of contacts are biologically releveant. It is therefore common to merge biological |
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54 and technical replicates of Hi-C experiments and **hicSumMatrix** address this concern. |
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55 |
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56 _________________ |
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57 |
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58 Usage |
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59 ----- |
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60 |
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61 This tool takes two or more Hi-C contact matrices and sum the contacts into one matrix. It is recommended to use uncorrected and unmerged matrices as input (use the direct output from ``hicBuildMatrix``). Bin merging (``hicMergeMatrixBins``) and Hi-C contact matrix correction (``hicCorrectMatrix``) must be performed afterwards. |
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62 |
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63 _________________ |
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64 |
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65 Output |
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66 ------ |
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67 **hicSumMatrix** outputs a Hi-C contact matrix comprising the sum of all the contacts of the Hi-C matrices used as input. |
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68 |
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69 _________________ |
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70 |
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71 | For more information about HiCExplorer please consider our documentation on readthedocs.io_ |
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72 |
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73 .. _readthedocs.io: http://hicexplorer.readthedocs.io/en/latest/index.html |
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74 ]]></help> |
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75 <expand macro="citations" /> |
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76 </tool> |