Mercurial > repos > bcclaywell > argo_navis
annotate bin/pact_wrapper.py @ 0:d67268158946 draft
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author | bcclaywell |
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date | Mon, 12 Oct 2015 17:43:33 -0400 |
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1 #!/usr/bin/env python |
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2 |
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3 import argparse |
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4 from os import path |
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5 import re |
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6 import os |
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7 import csv |
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8 import shutil |
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9 import subprocess |
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10 |
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11 |
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12 setting_template = """ |
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13 # TREE MANIPULATION |
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14 {prune} |
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15 |
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16 # TREE OUTPUT |
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17 print rule tree # print out the tree... |
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18 |
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19 # SUMMARY STATS |
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20 summary tmrca # time to mrca |
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21 summary proportions # proportions on trunk of geneology |
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22 summary coal rates # coalescent rates; separate for each label |
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23 summary mig rates # migration rates; separate for each label pair |
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24 #summary fst # diversity between vs within labels |
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25 |
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26 skyline settings -{sky_start} -{sky_end} {sky_interval} |
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27 skyline proportions |
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28 """ |
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29 |
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30 |
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31 def tips_from_label(meta_reader, label, deme_col="deme"): |
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32 return [row['sequence'] for row in meta_reader if row[deme_col] == label] |
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33 |
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34 def tips_from_labels(meta_reader, labels, deme_col="deme"): |
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35 return [row['sequence'] for row in meta_reader if row[deme_col] in labels] |
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36 |
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37 def translate_tips(tips, translation): |
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38 result = list() |
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39 for tip in tips: |
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40 try: |
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41 result.append(translation[tip]) |
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42 except KeyError: |
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43 pass |
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44 return result |
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45 |
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46 |
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47 def translation_from_nexus(handle): |
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48 """This reads the seqname -> id translation from the trees file. Should probably eventually move this out |
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49 and into a separate file so that we can use the results in plotting. Not now though...""" |
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50 in_trans = False |
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51 trans = dict() |
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52 for line in handle: |
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53 if re.search("Translate", line): |
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54 # This is the demarkator for the translation section of the nexus file |
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55 in_trans = True |
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56 continue |
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57 if in_trans: |
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58 if re.match(";", line): |
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59 # If we hit this, we've reached the end of the translation region |
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60 break |
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61 else: |
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62 # Otherwise we're still in the Translate region, so populate trans |
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63 index, name = line.strip().strip(',').split() |
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64 trans[name] = index |
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65 return trans |
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66 |
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67 |
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68 def prune_tips_string(tips, args): |
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69 if args.translate_trees: |
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70 trans = translation_from_nexus(file(args.trees_in)) |
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71 tips = translate_tips(tips, trans) |
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72 return "prune to tips " + " ".join(tips) |
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73 |
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74 |
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75 def prune_string(args): |
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76 if args.labels: |
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77 if args.metadata: |
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78 labels = args.labels.replace("\"", "").replace("'", "").split() |
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79 print "Pruning to labels:", labels |
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80 tips = tips_from_labels(csv.DictReader(args.metadata), labels, deme_col=args.deme_col) |
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81 print "Tips for labels are:", tips |
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82 return prune_tips_string(tips, args) |
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83 else: |
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84 return "prune to label " + args.labels |
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85 |
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86 elif args.tip_file or args.tips: |
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87 if args.tip_file: |
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88 tips = args.tip_file.read().split() |
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89 else: |
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90 tips = args.tips.replace("'", "").replace("\"", "").split() |
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91 print "Tips specified are:", tips |
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92 return prune_tips_string(tips, args) |
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93 else: |
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94 return "" |
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95 |
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96 |
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97 def get_args(): |
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98 parser = argparse.ArgumentParser() |
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99 parser.add_argument('trees_in') |
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100 parser.add_argument('-t', '--tips', help="List of tips in quotes") |
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101 parser.add_argument('-T', '--tip-file', help="File of tips sep by space", type=argparse.FileType('r')) |
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102 parser.add_argument('-r', '--translate-trees', action="store_true", default=False, |
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103 help="""If flagged, the trees_in file will be used for translating tip names from indices to actual |
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104 tip names; this is necessary for BEAST runs only""") |
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105 parser.add_argument('-m', '--metadata', type=argparse.FileType('r'), |
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106 help="""Required for filtering by deme/label with the beast method""") |
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107 parser.add_argument('-l', '--labels') |
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108 parser.add_argument('-s', '--sky-start', default=2.0, type=float, |
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109 help="How far back to compute skyline statistics (should be a potive number)") |
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110 parser.add_argument('-S', '--trim-start', type=float, |
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111 help="""Trim the tree from 0 back to the specified time; overrides sky-start for skyline plots. |
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112 (should be a positive number)""") |
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113 parser.add_argument('-e', '--trim-end', default=0.0, type=float, |
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114 help="Most recent time to trim to in time interval; will also be used for sky (should be non-negative)") |
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115 parser.add_argument('-o', '--out-dir') |
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116 parser.add_argument('-p', '--prune-to-trunk', action="store_true", default=False) |
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117 parser.add_argument('-d', '--deme-col', default="deme", help="Deme column in metadata file") |
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118 return parser.parse_args() |
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119 |
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120 |
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121 def main(): |
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122 args = get_args() |
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123 |
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124 # Create the param file in the proper directory |
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125 outfile = file(path.join(args.out_dir, 'in.param'), 'w') |
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126 |
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127 prune = prune_string(args) |
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128 if args.prune_to_trunk: |
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129 prune += "\nprune to trunk" |
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130 |
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131 if args.trim_start: |
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132 prune += "\ntrim ends -%s -%s" % (args.trim_start, args.trim_end) |
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133 |
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134 sky_start = args.trim_start if args.trim_start else args.sky_start |
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135 sky_end = args.trim_end |
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136 sky_interval = abs(sky_end - sky_start) / 100 |
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137 outfile.write(setting_template.format( |
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138 prune=prune, |
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139 sky_end=sky_end, |
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140 sky_start=sky_start, |
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141 sky_interval=sky_interval)) |
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142 outfile.close() |
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143 |
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144 # Copy the tree file over to the directory |
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145 shutil.copyfile(args.trees_in, path.join(args.out_dir, 'in.trees')) |
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146 |
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147 # Actually run PACT |
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148 os.chdir(args.out_dir) |
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149 subprocess.check_call(['pact']) |
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150 |
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151 |
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152 if __name__ == '__main__': |
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153 main() |
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154 |
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155 |