diff README.rst @ 80:ebb4c3b8b9db draft

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author stef
date Fri, 20 Mar 2015 08:58:17 -0400
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+FALCO Amplicon Analysis Pipeline & Galaxy wrapper
+========================================
+
+FALCO variant-caller is part of the Amplicon Analysis Pipeline (AAP).
+
+The typical workflow is as follows:
+* paired-end amplicon sequencing
+* merge pairs (so only overlapping pairs are included)
+* map the single read fastq with BWA
+* perform variant calling with FALCO
+* create (html) report of the results
+
+FALCO uses samtools and straight-forward statistics to determine wether a
+potential variant is likely a (technical) artifact or not.
+
+Input / Output
+
+Input of the caller is a BAM file, output VCF
+
+
+Bug Reports & other questions
+=============================
+
+Issues can be reported via http://www.tgac.nl/