# HG changeset patch
# User saketkc
# Date 1397581206 14400
# Node ID 699ab41c6d764f072ebadb64538087ee93936d31
# Parent 84247b644a7d29e288d44d698f1f991c6ae5a32b
Uploaded
diff -r 84247b644a7d -r 699ab41c6d76 condel_web/condel_web.xml
--- a/condel_web/condel_web.xml Mon Apr 14 21:37:22 2014 -0400
+++ b/condel_web/condel_web.xml Tue Apr 15 13:00:06 2014 -0400
@@ -2,7 +2,9 @@
Condel web service
requests
+ pycurl
requests
+ pycurl
condel_web.py --input $input --output $output
@@ -15,7 +17,7 @@
-
+
@@ -36,6 +38,53 @@
dataset of approximately 20000 missense SNPs, both deleterious and neutral. The probability that a predicted deleterious mutation is not a
false positive of the method and the probability that a predicted neutral mutation is not a false negative are employed as weights.
+ **Input**
+
+ There are two main formats allowed:
+
+
+ SNVs may be submitted for analysis both in chromosome and protein coordinates.
+
+
+ The chromosome coordinates (hg19) input must follow this format:
+
+
+ [CHROMOSOME] [START] [END] [MUTANT_NUCLEOTIDE]
+
+
+
+ The END column is the same as the START for SNVs.
+ Those four columns must be separated by tabs. Also a fifth column can optionally be added with the Variant name
+
+
+ Ex:
+
+ 9 32473058 32473058 A
+
+ 7 43918688 43918688 C
+
+ Additionally, the input could be composed by two columns the strand of the SNV and an identifier:
+
+ [PROTEIN_ID][variant]
+
+ Also tab separated. Currently only Uniprot, RefSeq_Peptide and Ensembl identifiers are recognized by the webserver.
+
+ The variant column must contain the following information (in this order ): change_position, reference_aminoacid and changed_aminoacid
+
+ Ex:
+
+ EGFR_HUMAN R521K
+
+ EGFR_HUMAN R98Q
+
+ .. class:: warningmark
+
+ Note
+
+ Please, note that the Variant Effect Predictor assumes that the allele submitted is coded in the forward strand.
+
+ If you are assessing the effect of variants coded in the reverse strand, please introduce the complementary nucleotide instead.
+
**Citation**
diff -r 84247b644a7d -r 699ab41c6d76 condel_web/test-data/condel_input.tsv
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/condel_web/test-data/condel_input.tsv Tue Apr 15 13:00:06 2014 -0400
@@ -0,0 +1,5 @@
+9 32473058 32473058 A
+7 43918688 43918688 C
+7 38471790 38471790 A
+6 88372821 88372821 A
+5 41934236 41934236 G
diff -r 84247b644a7d -r 699ab41c6d76 condel_web/test-data/condel_input.txt
--- a/condel_web/test-data/condel_input.txt Mon Apr 14 21:37:22 2014 -0400
+++ /dev/null Thu Jan 01 00:00:00 1970 +0000
@@ -1,5 +0,0 @@
-9 32473058 32473058 A
-7 43918688 43918688 C
-7 38471790 38471790 A
-6 88372821 88372821 A
-5 41934236 41934236 G
diff -r 84247b644a7d -r 699ab41c6d76 condel_web/tool_dependencies.xml
--- a/condel_web/tool_dependencies.xml Mon Apr 14 21:37:22 2014 -0400
+++ b/condel_web/tool_dependencies.xml Tue Apr 15 13:00:06 2014 -0400
@@ -1,6 +1,9 @@
-
-
+
+
+
+
+