# HG changeset patch # User mrvollger # Date 1418596509 18000 # Node ID 641ebb0ac52898dd97546bbbbff99f8abd307f5a # Parent 3684784b3087c313f144c3f466a91d8d6be12e7c Uploaded diff -r 3684784b3087 -r 641ebb0ac528 trtr.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/trtr.xml Sun Dec 14 17:35:09 2014 -0500 @@ -0,0 +1,43 @@ + + + trtr + + + Trim Reads of Tandem Repeat in a fastq file. + + + trtr $input $max_repeat $aggressive > $output + + + + + + + + + + + + + + + + + + + + + + + + +This tool removes tandem repeats from ends of unaligned sequencing reads (leaving one copy). This prevents reads that don't span the repeated region from overlapping and leading to innaccurate SNPs calls. + +The maximimum repeat length is adjustable (use 1 to trim only homopolymers). + +The "aggressive" option should not be touched in general. Setting to 0 will prevent the program from trimming to exactly 1 copy of the repeat, instead leaving between 1 and 2 copies. + +This could also be a useful first step before assembly. More testing needs to be done. + + +