# HG changeset patch
# User melissacline
# Date 1426894726 25200
# Node ID 3a259686f0fcc74b160810b5940bf373e7887b8b
# Parent  914bc8ee62224058e19a34fc8e53d58e59d0a1d9# Parent  0b0a6f326dad863bb2e66be88cbb03f942737f72
Merged with head, tweaked labels on merge mutation data tool

diff -r 914bc8ee6222 -r 3a259686f0fc mergeGenomicFiles.xml
--- a/mergeGenomicFiles.xml	Fri Mar 20 15:50:22 2015 -0700
+++ b/mergeGenomicFiles.xml	Fri Mar 20 16:38:46 2015 -0700
@@ -1,20 +1,31 @@
 <tool id="mergeGenomicFiles" description="Merge two genomic datasets into a new dataset" name="Merge Genomic Datasets" version="0.0.1">
   <description>
-    Given two genomic datasets, merge them to create a third dataset with the row and column identifiers from both datasets.
+    Given two genomic datasets, merge them to create a larger dataset with the row and column identifiers from both datasets. Output this larger dataset, along with a 2-column matrix indicating the source file of each sample
   </description>
   <command interpreter="python">
-      mergeGenomicMatrixFiles.py $outputC $inputA $inputB
+      mergeGenomicMatrixFiles.py $inputA $inputB $outputC $outputSourceMatrix
+      #if $labelForDatasetA
+          --aLabel "${labelForDatasetA}"
+      #end if
+      #if $labelForDatasetB
+          --bLabel "${labelForDatasetB}"
+      #end if
   </command>
   <inputs>
     <param name="inputA" format="tabular" type="data" label="Genomic Dataset A"/>
-    <param name="inputB" format="tabular" type="data" label="Genomic Dataset B"/>
-  </inputs>
+    <param type="text" name="labelForDatasetA"  label="Dataset A Label (optional)" optional="true"/>
+    <param name="inputB" format="tabular" type="data" label="Genomic Dataset B"/> 
+    <param type="text" name="labelForDatasetB"  label="Dataset B Label (optional)" optional="true"/>
+ </inputs>
   <outputs>
-    <data name="outputC" format="tabular"/>
+    <data name="outputSourceMatrix" format="tabular" label="Genomic Data Sources"/>
+    <data name="outputC" format="tabular" label="Merged Genomic Data"/>
   </outputs>
   <help>
     ***Merge Genomic Datasets***
 
-    Given two genomic datasets, merge them to produce a third dataset that is the union of the first two.  The new dataset will contain all column labels from either dataset, and all row labels from either dataset.  If a row label appears in both datasets, the output dataset will contain, for that row, all values for the first set of columns, plus all values for the second set of columns.  If a row label appears in the first dataset only, the output dataset will contain the values for the columns of the first dataset, and blanks (indicating missing values) for the columns of the second da
+    Given two genomic datasets, merge them to produce a third dataset that is the union of the first two.  The new dataset will contain all column labels from either dataset, and all row labels from either dataset.  If a row label appears in both datasets, the output dataset will contain, for that row, all values for the first set of columns, plus all values for the second set of columns.  If a row label appears in the first dataset only, the output dataset will contain the values for the columns of the first dataset, and blanks (indicating missing values) for the columns of the second dataset.
+
+    To maintain provenance, this script also outputs a second matrix, with one row for each column in the output dataset, and two columns per row indicating which input dataset that column came from.  By default, the input dataset name is used to indicate which input file each column came from.  Optionally, the user can specify descriptive labels to be used in place of the filenames.  This all assumes that each column exists in only one input dataset.
   </help>
 </tool>
diff -r 914bc8ee6222 -r 3a259686f0fc mergeGenomicMatrixFiles.py
--- a/mergeGenomicMatrixFiles.py	Fri Mar 20 15:50:22 2015 -0700
+++ b/mergeGenomicMatrixFiles.py	Fri Mar 20 16:38:46 2015 -0700
@@ -1,21 +1,27 @@
 #!/usr/bin/env python
 
+import argparse
 import string,os,sys
 
-def header (samples, infile):
-    fin= open(infile,'r')
+def header (samples, sourceFiles, infile, labelThisFile):
+    if labelThisFile == None:
+        labelToUse = infile
+    else:
+        labelToUse = labelThisFile
+    fin= open(infile, 'U')
     #header, samples
     newSamples = string.split(string.strip(fin.readline()),'\t')[1:]
     for sample in newSamples:
         if sample not in samples:
             samples[sample]= len(samples)
+            sourceFiles[sample] = labelToUse
     fin.close()
     return
 
 def process(genes, samples, dataMatrix, infile):
     maxLength= len(samples)
 
-    fin= open(infile,'r')
+    fin= open(infile,'U')
     #header 
     newSamples = string.split(string.strip(fin.readline()),'\t')
     
@@ -41,7 +47,17 @@
     fin.close()
     return
 
-def outputMatrix(dataMatrix, samples, genes, outfile):
+
+def outputSourceMatrix(sourceData, outputFileName):
+    fout = open(outputFileName, "w")
+    fout.write("Sample\tSource\n")
+    for thisSample in sourceData.keys():
+        fout.write("%s\t%s\n" % (thisSample, sourceData[thisSample]))
+    fout.close()
+    return
+
+
+def outputMergedMatrix(dataMatrix, samples, genes, outfile):
     fout = open(outfile,"w")
     maxLength= len(samples)
     sList=[]
@@ -66,23 +82,38 @@
     return
 
 if __name__ == '__main__' :
-    if len(sys.argv[:]) <4:
-        print "python mergeFilesByColumn.py output inputfile(s)"
-        print "**********memory intensive, not for very genomic data with hugo number of probes"
-        print "this is merging data A+B=C\n"
-        sys.exit()
-
-    inFiles = sys.argv[2:]
-    outfile = sys.argv[1]
+    #
+    # The input files to this script are two or more matrices, in which
+    # columns represent samples and rows represent genes or measurements.
+    # There are two output files: outMergedData contains the input data merged
+    # into a single matrix, and outSourceMatrix is a two-column matrix 
+    # indicating which file each sample (or column label) came from.  This
+    # assumes that each sample came from at most one file.
+    #
+    parser = argparse.ArgumentParser()
+    parser.add_argument("inFileA", type=str, help="First input file")
+    parser.add_argument("inFileB", type=str, help="Second input file")
+    parser.add_argument("outMergedData", type=str, 
+                        help="Filename for the merged dataset")
+    parser.add_argument("outSourceMatrix", type=str,
+                        help="""Filename for a Nx2 matrix that indicates
+                                the source file of each column""")
+    parser.add_argument("--aLabel", type=str, default=None,
+                        help="User-friendly label for the first input file")
+    parser.add_argument("--bLabel", type=str, default=None,
+                        help="User-friendly label for the second input file")
+    args = parser.parse_args()
 
     genes={}
     samples={}
+    sourceFiles = {}
     dataMatrix=[]
 
-    for infile in inFiles:
-        header (samples, infile)
+    header(samples, sourceFiles, args.inFileA, args.aLabel)
+    header(samples, sourceFiles, args.inFileB, args.bLabel)
 
-    for infile in inFiles:
-        process(genes, samples, dataMatrix, infile)
+    process(genes, samples, dataMatrix, args.inFileA)
+    process(genes, samples, dataMatrix, args.inFileB)
 
-    outputMatrix(dataMatrix, samples, genes, outfile)
+    outputSourceMatrix(sourceFiles, args.outSourceMatrix)
+    outputMergedMatrix(dataMatrix, samples, genes, args.outMergedData)
diff -r 914bc8ee6222 -r 3a259686f0fc mergeMutationDatasets.xml
--- a/mergeMutationDatasets.xml	Fri Mar 20 15:50:22 2015 -0700
+++ b/mergeMutationDatasets.xml	Fri Mar 20 16:38:46 2015 -0700
@@ -1,4 +1,4 @@
-<tool id="mergeMutationDatasets" description="Merge two mutation datasets into a new dataset" name="Merge Mutation Data" version="0.0.1">
+<tool id="mergeMutationDatasets" description="Merge two Xena positional mutation datasets into a new dataset" name="Merge Positional Mutation Data" version="0.0.1">
   <description>
     Given two mutation datasets, merge them to create a larger dataset with the mutations from both datasets. Output this larger dataset, along with a 2-column matrix indicating the source of each mutation
   </description>
@@ -23,7 +23,7 @@
     <data name="outputC" format="tabular" label="Merged Mutation Data"/>
   </outputs>
   <help>
-    ***Merge Xena Mutation Datasets***
+    ***Merge Xena Positional Mutation Datasets***
 
     Given two datasets of mutation data as formatted for the UCSC Xena Browser, merge them to produce a third dataset that is the union of the first two.  The new dataset will contain all mutations from either dataset. 
 
diff -r 914bc8ee6222 -r 3a259686f0fc tool_dependencies.xml
--- a/tool_dependencies.xml	Fri Mar 20 15:50:22 2015 -0700
+++ b/tool_dependencies.xml	Fri Mar 20 16:38:46 2015 -0700
@@ -1,7 +1,7 @@
 <?xml version="1.0"?>
 <tool_dependency>
-  <package name="synapseClient" version="1.0">
-    <install version="1.0">
+  <package name="synapseClient" version="1.2">
+    <install version="1.2">
       <actions>
 	<action type="setup_virtualenv">
 	  synapseclient