Mercurial > repos > melissacline > ucsc_cancer_utilities
comparison seg2matrix/segToMatrixGalaxy.py @ 54:59dbe857f5d4
introduce normal_CNV parameter
author | jingchunzhu |
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date | Thu, 17 Sep 2015 22:03:04 -0700 |
parents | 7de3db823f90 |
children | bf57076e27b9 |
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53:7de3db823f90 | 54:59dbe857f5d4 |
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31 self.chrom_end = chrom_end | 31 self.chrom_end = chrom_end |
32 self.strand = "." | 32 self.strand = "." |
33 | 33 |
34 | 34 |
35 if __name__ == "__main__": | 35 if __name__ == "__main__": |
36 if len(sys.argv[:])!= 5: | 36 if len(sys.argv[:])!= 6: |
37 print "python segToMatrixGalaxy.py inputSegmentFile refGeneFile outputMatrix outputProbeMap\n" | 37 print "python segToMatrixGalaxy.py inputSegmentFile refGeneFile outputMatrix outputProbeMap NORMAL_CNV\n" |
38 sys.exit() | 38 sys.exit() |
39 seg = CGData.GenomicSegment.GenomicSegment() | 39 seg = CGData.GenomicSegment.GenomicSegment() |
40 seg.load(sys.argv[1]) | 40 seg.load(sys.argv[1]) |
41 | 41 |
42 refgene = CGData.RefGene.RefGene() | 42 refgene = CGData.RefGene.RefGene() |
43 refgene.load(sys.argv[2]) | 43 refgene.load(os.path.dirname(sys.argv[0])+"/"+os.path.basename(sys.argv[2])) |
44 # refgene.load(os.path.dirname(sys.argv[0])+"/"+sys.argv[2]) | 44 |
45 NORMAL_CNV = sys.argv[5] | |
45 | 46 |
46 handle = open(sys.argv[3], "w") | 47 handle = open(sys.argv[3], "w") |
47 m = matrix_write(handle) | 48 m = matrix_write(handle) |
48 CGData.SegToMatrix.seg_to_matrix(seg, m) | 49 CGData.SegToMatrix.seg_to_matrix(seg, m, NORMAL_CNV) |
49 handle.close() | 50 handle.close() |
50 | 51 |
51 handle = open(sys.argv[4], "w") | 52 handle = open(sys.argv[4], "w") |
52 probeMapper = CGData.GeneMap.ProbeMapper('b') | 53 probeMapper = CGData.GeneMap.ProbeMapper('b') |
53 handle.write("%s\t%s\t%s\t%s\t%s\t%s\n" % ("#id", "gene","chrom","chromStart","chromEnd","strand")) | 54 handle.write("%s\t%s\t%s\t%s\t%s\t%s\n" % ("id", "gene","chrom","chromStart","chromEnd","strand")) |
54 for probe in m.probes: | 55 for probe in m.probes: |
55 hits = [] | 56 hits = [] |
56 for hit in probeMapper.find_overlap( probe, refgene ): | 57 for hit in probeMapper.find_overlap( probe, refgene ): |
57 if hit.name not in hits: | 58 if hit.name not in hits: |
58 hits.append(hit.name) | 59 hits.append(hit.name) |