comparison variant_effect_predictor/Bio/Ontology/OntologyEngineI.pm @ 0:1f6dce3d34e0

Uploaded
author mahtabm
date Thu, 11 Apr 2013 02:01:53 -0400
parents
children
comparison
equal deleted inserted replaced
-1:000000000000 0:1f6dce3d34e0
1 # $Id: OntologyEngineI.pm,v 1.2.2.3 2003/03/27 10:07:56 lapp Exp $
2 #
3 # BioPerl module for OntologyEngineI
4 #
5 # Cared for by Peter Dimitrov <dimitrov@gnf.org>
6 #
7 # (c) Peter Dimitrov
8 # (c) GNF, Genomics Institute of the Novartis Research Foundation, 2002.
9 #
10 # You may distribute this module under the same terms as perl itself.
11 # Refer to the Perl Artistic License (see the license accompanying this
12 # software package, or see http://www.perl.com/language/misc/Artistic.html)
13 # for the terms under which you may use, modify, and redistribute this module.
14 #
15 # THIS PACKAGE IS PROVIDED "AS IS" AND WITHOUT ANY EXPRESS OR IMPLIED
16 # WARRANTIES, INCLUDING, WITHOUT LIMITATION, THE IMPLIED WARRANTIES OF
17 # MERCHANTIBILITY AND FITNESS FOR A PARTICULAR PURPOSE.
18 #
19 # You may distribute this module under the same terms as perl itself
20
21 # POD documentation - main docs before the code
22
23 =head1 NAME
24
25 OntologyEngineI - Interface a minimal Ontology implementation should satisfy
26
27 =head1 SYNOPSIS
28
29 # see documentation of methods
30
31 =head1 DESCRIPTION
32
33 This describes the minimal interface an ontology query engine should
34 provide. It intentionally doesn't make explicit references to the
35 ontology being a DAG, nor does it mandate that the ontology be a
36 vocabulary. Rather, it tries to generically express what should be
37 accessible (queriable) about an ontology.
38
39 The idea is to allow for different implementations for different
40 purposes, which may then differ as to which operations are efficient
41 and which aren't, and how much richer the functionality is on top of
42 this minimalistic set of methods. Check modules in the Bio::Ontology
43 namespace to find out which implementations exist. At the time of
44 writing, there is a SimpleOntologyEngine (which does not use
45 Graph.pm), and a Graph.pm-based implementation in SimpleGOEngine.
46
47 Ontology parsers in Bio::OntologyIO are required to return an
48 implementation of this interface.
49
50 =head1 FEEDBACK
51
52 =head2 Mailing Lists
53
54 User feedback is an integral part of the evolution of this and other
55 Bioperl modules. Send your comments and suggestions preferably to
56 the Bioperl mailing list. Your participation is much appreciated.
57
58 bioperl-l@bioperl.org - General discussion
59 http://bioperl.org/MailList.shtml - About the mailing lists
60
61 =head2 Reporting Bugs
62
63 Report bugs to the Bioperl bug tracking system to help us keep track
64 of the bugs and their resolution. Bug reports can be submitted via
65 email or the web:
66
67 bioperl-bugs@bioperl.org
68 http://bugzilla.bioperl.org/
69
70 =head1 AUTHOR - Peter Dimitrov
71
72 Email dimitrov@gnf.org
73
74 Describe contact details here
75
76 =head1 CONTRIBUTORS
77
78 Additional contributors names and emails here
79
80 =head1 APPENDIX
81
82 The rest of the documentation details each of the object methods.
83 Internal methods are usually preceded with a _
84
85 =cut
86
87
88 # Let the code begin...
89
90
91 package Bio::Ontology::OntologyEngineI;
92 use vars qw(@ISA);
93 use strict;
94 use Carp;
95 use Bio::Root::RootI;
96
97 @ISA = qw( Bio::Root::RootI );
98
99 =head2 add_term
100
101 Title : add_term
102 Usage : add_term(TermI term): TermI
103 Function: Adds TermI object to the ontology engine term store
104 Example : $oe->add_term($term)
105 Returns : its argument.
106 Args : object of class TermI.
107
108
109 =cut
110
111 sub add_term{
112 shift->throw_not_implemented();
113 }
114
115 =head2 add_relationship
116
117 Title : add_relationship
118 Usage : add_relationship(RelationshipI relationship): RelationshipI
119 Function: Adds a relationship object to the ontology engine.
120 Example :
121 Returns : Its argument.
122 Args : A RelationshipI object.
123
124
125 =cut
126
127 sub add_relationship{
128 shift->throw_not_implemented();
129 }
130
131 =head2 get_relationships
132
133 Title : get_relationships
134 Usage : get_relationships(TermI term): RelationshipI[]
135 Function: Retrieves all relationship objects from this ontology engine,
136 or all relationships of a term if a term is supplied.
137 Example :
138 Returns : Array of Bio::Ontology::RelationshipI objects
139 Args : None, or a Bio::Ontology::TermI compliant object for which
140 to retrieve the relationships.
141
142
143 =cut
144
145 sub get_relationships{
146 shift->throw_not_implemented();
147 }
148
149 =head2 get_predicate_terms
150
151 Title : get_predicate_terms
152 Usage : get_predicate_terms(): TermI[]
153 Function:
154 Example :
155 Returns :
156 Args :
157
158
159 =cut
160
161 sub get_predicate_terms{
162 shift->throw_not_implemented();
163 }
164
165 =head2 get_child_terms
166
167 Title : get_child_terms
168 Usage : get_child_terms(TermI term, TermI[] predicate_terms): TermI[]
169 Function: Retrieves all child terms of a given term, that satisfy a
170 relationship among those that are specified in the second
171 argument or undef otherwise. get_child_terms is a special
172 case of get_descendant_terms, limiting the search to the
173 direct descendants.
174
175 Example :
176 Returns : Array of TermI objects.
177 Args : First argument is the term of interest, second is the list
178 of relationship type terms.
179
180
181 =cut
182
183 sub get_child_terms{
184 shift->throw_not_implemented();
185 }
186
187 =head2 get_descendant_terms
188
189 Title : get_descendant_terms
190 Usage : get_descendant_terms(TermI term, TermI[] rel_types): TermI[]
191 Function: Retrieves all descendant terms of a given term, that
192 satisfy a relationship among those that are specified in
193 the second argument or undef otherwise.
194 Example :
195 Returns : Array of TermI objects.
196 Args : First argument is the term of interest, second is the list
197 of relationship type terms.
198
199
200 =cut
201
202 sub get_descendant_terms{
203 shift->throw_not_implemented();
204 }
205
206 =head2 get_parent_terms
207
208 Title : get_parent_terms
209 Usage : get_parent_terms(TermI term, TermI[] predicate_terms): TermI[]
210 Function: Retrieves all parent terms of a given term, that satisfy a
211 relationship among those that are specified in the second
212 argument or undef otherwise. get_parent_terms is a special
213 case of get_ancestor_terms, limiting the search to the
214 direct ancestors.
215
216 Example :
217 Returns : Array of TermI objects.
218 Args : First argument is the term of interest, second is the list
219 of relationship type terms.
220
221
222 =cut
223
224 sub get_parent_terms{
225 shift->throw_not_implemented();
226 }
227
228 =head2 get_ancestor_terms
229
230 Title : get_ancestor_terms
231 Usage : get_ancestor_terms(TermI term, TermI[] predicate_terms): TermI[]
232 Function: Retrieves all ancestor terms of a given term, that satisfy
233 a relationship among those that are specified in the second
234 argument or undef otherwise.
235
236 Example :
237 Returns : Array of TermI objects.
238 Args : First argument is the term of interest, second is the list
239 of relationship type terms.
240
241
242 =cut
243
244 sub get_ancestor_terms{
245 shift->throw_not_implemented();
246 }
247
248 =head2 get_leaf_terms
249
250 Title : get_leaf_terms
251 Usage : get_leaf_terms(): TermI[]
252 Function: Retrieves all leaf terms from the ontology. Leaf term is a
253 term w/o descendants.
254
255 Example : @leaf_terms = $obj->get_leaf_terms()
256 Returns : Array of TermI objects.
257 Args :
258
259
260 =cut
261
262 sub get_leaf_terms{
263 shift->throw_not_implemented();
264 }
265
266 =head2 get_root_terms
267
268 Title : get_root_terms
269 Usage : get_root_terms(): TermI[]
270 Function: Retrieves all root terms from the ontology. Root term is a
271 term w/o ancestors.
272
273 Example : @root_terms = $obj->get_root_terms()
274 Returns : Array of TermI objects.
275 Args :
276
277
278 =cut
279
280 sub get_root_terms{
281 shift->throw_not_implemented();
282 }
283
284 =head1 Factory for relationships and terms
285
286 =cut
287
288 =head2 relationship_factory
289
290 Title : relationship_factory
291 Usage : $fact = $obj->relationship_factory()
292 Function: Get (and set, if the implementation supports it) the object
293 factory to be used when relationship objects are created by
294 the implementation on-the-fly.
295
296 Example :
297 Returns : value of relationship_factory (a Bio::Factory::ObjectFactory
298 compliant object)
299 Args :
300
301
302 =cut
303
304 sub relationship_factory{
305 return shift->throw_not_implemented();
306 }
307
308 =head2 term_factory
309
310 Title : term_factory
311 Usage : $fact = $obj->term_factory()
312 Function: Get (and set, if the implementation supports it) the object
313 factory to be used when term objects are created by
314 the implementation on-the-fly.
315
316 Example :
317 Returns : value of term_factory (a Bio::Factory::ObjectFactory
318 compliant object)
319 Args :
320
321
322 =cut
323
324 sub term_factory{
325 return shift->throw_not_implemented();
326 }
327
328 =head1 Decorator Methods
329
330 These methods come with a default implementation that uses the
331 abstract methods defined for this interface. This may not be very
332 efficient, and hence implementors are encouraged to override these
333 methods if they can provide more efficient implementations.
334
335 =cut
336
337 =head2 get_all_terms
338
339 Title : get_all_terms
340 Usage : get_all_terms: TermI[]
341 Function: Retrieves all terms from the ontology.
342
343 This is more a decorator method. We provide a default
344 implementation here that loops over all root terms and gets
345 all descendants for each root term. The overall union of
346 terms is then made unique by name and ontology.
347
348 We do not mandate an order here in which the terms are
349 returned. In fact, the default implementation will return
350 them in unpredictable order.
351
352 Engine implementations that can provide a more efficient
353 method for obtaining all terms should definitely override
354 this.
355
356 Example : @terms = $obj->get_all_terms()
357 Returns : Array of TermI objects.
358 Args :
359
360
361 =cut
362
363 sub get_all_terms{
364 my $self = shift;
365 # get all root nodes
366 my @roots = $self->get_root_terms();
367 # accumulate all descendants for each root term
368 my @terms = map { $self->get_descendant_terms($_); } @roots;
369 # add on the root terms themselves
370 push(@terms, @roots);
371 # make unique by name and ontology
372 my %name_map = map { ($_->name."@".$_->ontology->name, $_); } @terms;
373 # done
374 return values %name_map;
375 }
376
377 =head2 find_terms
378
379 Title : find_terms
380 Usage : ($term) = $oe->find_terms(-identifier => "SO:0000263");
381 Function: Find term instances matching queries for their attributes.
382
383 An implementation may not support querying for arbitrary
384 attributes, but can generally be expected to accept
385 -identifier and -name as queries. If both are provided,
386 they are implicitly intersected.
387
388 Example :
389 Returns : an array of zero or more Bio::Ontology::TermI objects
390 Args : Named parameters. The following parameters should be recognized
391 by any implementation:
392
393 -identifier query by the given identifier
394 -name query by the given name
395
396
397 =cut
398
399 sub find_terms{
400 my $self = shift;
401 my %params = @_;
402 @params{ map { lc $_; } keys %params } = values %params; # lowercase keys
403
404 my @terms = grep {
405 my $ok = exists($params{-identifier}) ?
406 $_->identifier() eq $params{-identifier} : 1;
407 $ok && ((! exists($params{-name})) ||
408 ($_->name() eq $params{-name}));
409 } $self->get_all_terms();
410 return @terms;
411 }
412
413 1;