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comparison variant_effect_predictor/Bio/LocationI.pm @ 0:1f6dce3d34e0
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| author | mahtabm |
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| date | Thu, 11 Apr 2013 02:01:53 -0400 |
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| -1:000000000000 | 0:1f6dce3d34e0 |
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| 1 # $Id: LocationI.pm,v 1.18 2002/12/01 00:05:19 jason Exp $ | |
| 2 # | |
| 3 # BioPerl module for Bio::LocationI | |
| 4 # Cared for by Jason Stajich <jason@bioperl.org> | |
| 5 # | |
| 6 # Copyright Jason Stajich | |
| 7 # | |
| 8 # You may distribute this module under the same terms as perl itself | |
| 9 # POD documentation - main docs before the code | |
| 10 | |
| 11 =head1 NAME | |
| 12 | |
| 13 Bio::LocationI - Abstract interface of a Location on a Sequence | |
| 14 | |
| 15 =head1 SYNOPSIS | |
| 16 | |
| 17 # get a LocationI somehow | |
| 18 printf( "start = %d, end = %d, strand = %s, seq_id = %s\n", | |
| 19 $location->start, $location->end, $location->strand, | |
| 20 $location->seq_id); | |
| 21 print "location str is ", $location->to_FTstring(), "\n"; | |
| 22 | |
| 23 | |
| 24 =head1 DESCRIPTION | |
| 25 | |
| 26 This Interface defines the methods for a Bio::LocationI, an object | |
| 27 which encapsulates a location on a biological sequence. Locations | |
| 28 need not be attached to actual sequences as they are stand alone | |
| 29 objects. LocationI objects are used by L<Bio::SeqFeatureI> objects to | |
| 30 manage and represent locations for a Sequence Feature. | |
| 31 | |
| 32 =head1 FEEDBACK | |
| 33 | |
| 34 User feedback is an integral part of the evolution of this and other | |
| 35 Bioperl modules. Send your comments and suggestions preferably to one | |
| 36 of the Bioperl mailing lists. Your participation is much appreciated. | |
| 37 | |
| 38 bioperl-l@bioperl.org - General discussion | |
| 39 http://bio.perl.org/MailList.html - About the mailing lists | |
| 40 | |
| 41 =head2 Reporting Bugs | |
| 42 | |
| 43 Report bugs to the Bioperl bug tracking system to help us keep track | |
| 44 the bugs and their resolution. Bug reports can be submitted via email | |
| 45 or the web: | |
| 46 | |
| 47 bioperl-bugs@bio.perl.org | |
| 48 http://bugzilla.bioperl.org/ | |
| 49 | |
| 50 =head1 AUTHOR - Jason Stajich | |
| 51 | |
| 52 Email jason@bioperl.org | |
| 53 | |
| 54 =head1 APPENDIX | |
| 55 | |
| 56 The rest of the documentation details each of the object | |
| 57 methods. Internal methods are usually preceded with a _ | |
| 58 | |
| 59 =cut | |
| 60 | |
| 61 # Let the code begin... | |
| 62 | |
| 63 package Bio::LocationI; | |
| 64 use vars qw(@ISA $coord_policy); | |
| 65 use strict; | |
| 66 | |
| 67 use Bio::RangeI; | |
| 68 use Bio::Location::WidestCoordPolicy; | |
| 69 use Carp; | |
| 70 | |
| 71 @ISA = qw(Bio::RangeI); | |
| 72 | |
| 73 BEGIN { | |
| 74 $coord_policy = Bio::Location::WidestCoordPolicy->new(); | |
| 75 } | |
| 76 | |
| 77 =head2 location_type | |
| 78 | |
| 79 Title : location_type | |
| 80 Usage : my $location_type = $location->location_type(); | |
| 81 Function: Get location type encoded as text | |
| 82 Returns : string ('EXACT', 'WITHIN', 'BETWEEN') | |
| 83 Args : none | |
| 84 | |
| 85 =cut | |
| 86 | |
| 87 sub location_type { | |
| 88 my ($self,@args) = @_; | |
| 89 $self->throw_not_implemented(); | |
| 90 } | |
| 91 | |
| 92 =head2 start | |
| 93 | |
| 94 Title : start | |
| 95 Usage : $start = $location->start(); | |
| 96 Function: Get the start coordinate of this location as defined by | |
| 97 the currently active coordinate computation policy. In | |
| 98 simple cases, this will return the same number as | |
| 99 min_start() and max_start(), in more ambiguous cases like | |
| 100 fuzzy locations the number may be equal to one or neither | |
| 101 of both. | |
| 102 | |
| 103 We override this here from RangeI in order to delegate | |
| 104 'get' to a L<Bio::Location::CoordinatePolicy> implementing | |
| 105 object. Implementing classes may also wish to provide | |
| 106 'set' functionality, in which case they *must* override | |
| 107 this method. The implementation provided here will throw | |
| 108 an exception if called with arguments. | |
| 109 | |
| 110 Returns : A positive integer value. | |
| 111 Args : none | |
| 112 | |
| 113 See L<Bio::Location::CoordinatePolicy> for more information | |
| 114 | |
| 115 =cut | |
| 116 | |
| 117 sub start { | |
| 118 my ($self,@args) = @_; | |
| 119 | |
| 120 # throw if @args means that we don't support updating information | |
| 121 # in the interface but will delegate to the coordinate policy object | |
| 122 # for interpreting the 'start' value | |
| 123 | |
| 124 $self->throw_not_implemented if @args; | |
| 125 return $self->coordinate_policy()->start($self); | |
| 126 } | |
| 127 | |
| 128 =head2 end | |
| 129 | |
| 130 Title : end | |
| 131 Usage : $end = $location->end(); | |
| 132 Function: Get the end coordinate of this location as defined by the | |
| 133 currently active coordinate computation policy. In simple | |
| 134 cases, this will return the same number as min_end() and | |
| 135 max_end(), in more ambiguous cases like fuzzy locations | |
| 136 the number may be equal to one or neither of both. | |
| 137 | |
| 138 We override this here from Bio::RangeI in order to delegate | |
| 139 'get' to a L<Bio::Location::CoordinatePolicy> implementing | |
| 140 object. Implementing classes may also wish to provide | |
| 141 'set' functionality, in which case they *must* override | |
| 142 this method. The implementation provided here will throw | |
| 143 an exception if called with arguments. | |
| 144 | |
| 145 Returns : A positive integer value. | |
| 146 Args : none | |
| 147 | |
| 148 See L<Bio::Location::CoordinatePolicy> and L<Bio::RangeI> for more | |
| 149 information | |
| 150 | |
| 151 =cut | |
| 152 | |
| 153 sub end { | |
| 154 my ($self,@args) = @_; | |
| 155 | |
| 156 # throw if @args means that we don't support updating information | |
| 157 # in the interface but will delegate to the coordinate policy object | |
| 158 # for interpreting the 'end' value | |
| 159 $self->throw_not_implemented if @args; | |
| 160 return $self->coordinate_policy()->end($self); | |
| 161 } | |
| 162 | |
| 163 =head2 min_start | |
| 164 | |
| 165 Title : min_start | |
| 166 Usage : my $minstart = $location->min_start(); | |
| 167 Function: Get minimum starting point of feature. | |
| 168 | |
| 169 Note that an implementation must not call start() in this method. | |
| 170 | |
| 171 Returns : integer or undef if no minimum starting point. | |
| 172 Args : none | |
| 173 | |
| 174 =cut | |
| 175 | |
| 176 sub min_start { | |
| 177 my($self) = @_; | |
| 178 $self->throw_not_implemented(); | |
| 179 } | |
| 180 | |
| 181 =head2 max_start | |
| 182 | |
| 183 Title : max_start | |
| 184 Usage : my $maxstart = $location->max_start(); | |
| 185 Function: Get maximum starting point of feature. | |
| 186 | |
| 187 Note that an implementation must not call start() in this method | |
| 188 unless start() is overridden such as not to delegate to the | |
| 189 coordinate computation policy object. | |
| 190 | |
| 191 Returns : integer or undef if no maximum starting point. | |
| 192 Args : none | |
| 193 | |
| 194 =cut | |
| 195 | |
| 196 sub max_start { | |
| 197 my($self) = @_; | |
| 198 $self->throw_not_implemented(); | |
| 199 } | |
| 200 | |
| 201 =head2 start_pos_type | |
| 202 | |
| 203 Title : start_pos_type | |
| 204 Usage : my $start_pos_type = $location->start_pos_type(); | |
| 205 Function: Get start position type encoded as text | |
| 206 | |
| 207 Known valid values are 'BEFORE' (<5..100), 'AFTER' (>5..100), | |
| 208 'EXACT' (5..100), 'WITHIN' ((5.10)..100), 'BETWEEN', (5^6), with | |
| 209 their meaning best explained by their GenBank/EMBL location string | |
| 210 encoding in brackets. | |
| 211 | |
| 212 Returns : string ('BEFORE', 'AFTER', 'EXACT','WITHIN', 'BETWEEN') | |
| 213 Args : none | |
| 214 | |
| 215 =cut | |
| 216 | |
| 217 sub start_pos_type { | |
| 218 my($self) = @_; | |
| 219 $self->throw_not_implemented(); | |
| 220 } | |
| 221 | |
| 222 =head2 min_end | |
| 223 | |
| 224 Title : min_end | |
| 225 Usage : my $minend = $location->min_end(); | |
| 226 Function: Get minimum ending point of feature. | |
| 227 | |
| 228 Note that an implementation must not call end() in this method | |
| 229 unless end() is overridden such as not to delegate to the | |
| 230 coordinate computation policy object. | |
| 231 | |
| 232 Returns : integer or undef if no minimum ending point. | |
| 233 Args : none | |
| 234 | |
| 235 =cut | |
| 236 | |
| 237 sub min_end { | |
| 238 my($self) = @_; | |
| 239 $self->throw_not_implemented(); | |
| 240 } | |
| 241 | |
| 242 =head2 max_end | |
| 243 | |
| 244 Title : max_end | |
| 245 Usage : my $maxend = $location->max_end(); | |
| 246 Function: Get maximum ending point of feature. | |
| 247 | |
| 248 Note that an implementation must not call end() in this method | |
| 249 unless end() is overridden such as not to delegate to the | |
| 250 coordinate computation policy object. | |
| 251 | |
| 252 Returns : integer or undef if no maximum ending point. | |
| 253 Args : none | |
| 254 | |
| 255 =cut | |
| 256 | |
| 257 sub max_end { | |
| 258 my($self) = @_; | |
| 259 $self->throw_not_implemented(); | |
| 260 } | |
| 261 | |
| 262 =head2 end_pos_type | |
| 263 | |
| 264 Title : end_pos_type | |
| 265 Usage : my $end_pos_type = $location->end_pos_type(); | |
| 266 Function: Get end position encoded as text. | |
| 267 | |
| 268 Known valid values are 'BEFORE' (5..<100), 'AFTER' (5..>100), | |
| 269 'EXACT' (5..100), 'WITHIN' (5..(90.100)), 'BETWEEN', (5^6), with | |
| 270 their meaning best explained by their GenBank/EMBL location string | |
| 271 encoding in brackets. | |
| 272 | |
| 273 Returns : string ('BEFORE', 'AFTER', 'EXACT','WITHIN', 'BETWEEN') | |
| 274 Args : none | |
| 275 | |
| 276 =cut | |
| 277 | |
| 278 sub end_pos_type { | |
| 279 my($self) = @_; | |
| 280 $self->throw_not_implemented(); | |
| 281 } | |
| 282 | |
| 283 =head2 seq_id | |
| 284 | |
| 285 Title : seq_id | |
| 286 Usage : my $seqid = $location->seq_id(); | |
| 287 Function: Get/Set seq_id that location refers to | |
| 288 Returns : seq_id (a string) | |
| 289 Args : [optional] seq_id value to set | |
| 290 | |
| 291 =cut | |
| 292 | |
| 293 sub seq_id { | |
| 294 my ($self, $seqid) = @_; | |
| 295 if( defined $seqid ) { | |
| 296 $self->{'_seqid'} = $seqid; | |
| 297 } | |
| 298 return $self->{'_seqid'}; | |
| 299 } | |
| 300 | |
| 301 =head2 is_remote | |
| 302 | |
| 303 Title : is_remote | |
| 304 Usage : $is_remote_loc = $loc->is_remote() | |
| 305 Function: Whether or not a location is a remote location. | |
| 306 | |
| 307 A location is said to be remote if it is on a different | |
| 308 'object' than the object which 'has' this | |
| 309 location. Typically, features on a sequence will sometimes | |
| 310 have a remote location, which means that the location of | |
| 311 the feature is on a different sequence than the one that is | |
| 312 attached to the feature. In such a case, $loc->seq_id will | |
| 313 be different from $feat->seq_id (usually they will be the | |
| 314 same). | |
| 315 | |
| 316 While this may sound weird, it reflects the location of the | |
| 317 kind of AB18375:450-900 which can be found in GenBank/EMBL | |
| 318 feature tables. | |
| 319 | |
| 320 Example : | |
| 321 Returns : TRUE if the location is a remote location, and FALSE otherwise | |
| 322 Args : | |
| 323 | |
| 324 | |
| 325 =cut | |
| 326 | |
| 327 sub is_remote{ | |
| 328 shift->throw_not_implemented(); | |
| 329 } | |
| 330 | |
| 331 =head2 coordinate_policy | |
| 332 | |
| 333 Title : coordinate_policy | |
| 334 Usage : $policy = $location->coordinate_policy(); | |
| 335 $location->coordinate_policy($mypolicy); # set may not be possible | |
| 336 Function: Get the coordinate computing policy employed by this object. | |
| 337 | |
| 338 See L<Bio::Location::CoordinatePolicyI> for documentation | |
| 339 about the policy object and its use. | |
| 340 | |
| 341 The interface *does not* require implementing classes to | |
| 342 accept setting of a different policy. The implementation | |
| 343 provided here does, however, allow to do so. | |
| 344 | |
| 345 Implementors of this interface are expected to initialize | |
| 346 every new instance with a | |
| 347 L<Bio::Location::CoordinatePolicyI> object. The | |
| 348 implementation provided here will return a default policy | |
| 349 object if none has been set yet. To change this default | |
| 350 policy object call this method as a class method with an | |
| 351 appropriate argument. Note that in this case only | |
| 352 subsequently created Location objects will be affected. | |
| 353 | |
| 354 Returns : A L<Bio::Location::CoordinatePolicyI> implementing object. | |
| 355 Args : On set, a L<Bio::Location::CoordinatePolicyI> implementing object. | |
| 356 | |
| 357 See L<Bio::Location::CoordinatePolicyI> for more information | |
| 358 | |
| 359 | |
| 360 =cut | |
| 361 | |
| 362 sub coordinate_policy { | |
| 363 my ($self, $policy) = @_; | |
| 364 | |
| 365 if(defined($policy)) { | |
| 366 if(! $policy->isa('Bio::Location::CoordinatePolicyI')) { | |
| 367 $self->throw("Object of class ".ref($policy)." does not implement". | |
| 368 " Bio::Location::CoordinatePolicyI"); | |
| 369 } | |
| 370 if(ref($self)) { | |
| 371 $self->{'_coordpolicy'} = $policy; | |
| 372 } else { | |
| 373 # called as class method | |
| 374 $coord_policy = $policy; | |
| 375 } | |
| 376 } | |
| 377 return (ref($self) && exists($self->{'_coordpolicy'}) ? | |
| 378 $self->{'_coordpolicy'} : $coord_policy); | |
| 379 } | |
| 380 | |
| 381 =head2 to_FTstring | |
| 382 | |
| 383 Title : to_FTstring | |
| 384 Usage : my $locstr = $location->to_FTstring() | |
| 385 Function: returns the FeatureTable string of this location | |
| 386 Returns : string | |
| 387 Args : none | |
| 388 | |
| 389 =cut | |
| 390 | |
| 391 sub to_FTstring { | |
| 392 my($self) = @_; | |
| 393 $self->throw_not_implemented(); | |
| 394 } | |
| 395 | |
| 396 =head2 each_Location | |
| 397 | |
| 398 Title : each_Location | |
| 399 Usage : @locations = $locObject->each_Location($order); | |
| 400 Function: Conserved function call across Location:: modules - will | |
| 401 return an array containing the component Location(s) in | |
| 402 that object, regardless if the calling object is itself a | |
| 403 single location or one containing sublocations. | |
| 404 Returns : an array of Bio::LocationI implementing objects | |
| 405 Args : Optional sort order to be passed to sub_Location() for Splits | |
| 406 | |
| 407 =cut | |
| 408 | |
| 409 sub each_Location { | |
| 410 my ($self,@args) = @_; | |
| 411 $self->throw_not_implemented(); | |
| 412 } | |
| 413 | |
| 414 1; | |
| 415 |
