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comparison variant_effect_predictor/Bio/LocationI.pm @ 0:1f6dce3d34e0
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date | Thu, 11 Apr 2013 02:01:53 -0400 |
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1 # $Id: LocationI.pm,v 1.18 2002/12/01 00:05:19 jason Exp $ | |
2 # | |
3 # BioPerl module for Bio::LocationI | |
4 # Cared for by Jason Stajich <jason@bioperl.org> | |
5 # | |
6 # Copyright Jason Stajich | |
7 # | |
8 # You may distribute this module under the same terms as perl itself | |
9 # POD documentation - main docs before the code | |
10 | |
11 =head1 NAME | |
12 | |
13 Bio::LocationI - Abstract interface of a Location on a Sequence | |
14 | |
15 =head1 SYNOPSIS | |
16 | |
17 # get a LocationI somehow | |
18 printf( "start = %d, end = %d, strand = %s, seq_id = %s\n", | |
19 $location->start, $location->end, $location->strand, | |
20 $location->seq_id); | |
21 print "location str is ", $location->to_FTstring(), "\n"; | |
22 | |
23 | |
24 =head1 DESCRIPTION | |
25 | |
26 This Interface defines the methods for a Bio::LocationI, an object | |
27 which encapsulates a location on a biological sequence. Locations | |
28 need not be attached to actual sequences as they are stand alone | |
29 objects. LocationI objects are used by L<Bio::SeqFeatureI> objects to | |
30 manage and represent locations for a Sequence Feature. | |
31 | |
32 =head1 FEEDBACK | |
33 | |
34 User feedback is an integral part of the evolution of this and other | |
35 Bioperl modules. Send your comments and suggestions preferably to one | |
36 of the Bioperl mailing lists. Your participation is much appreciated. | |
37 | |
38 bioperl-l@bioperl.org - General discussion | |
39 http://bio.perl.org/MailList.html - About the mailing lists | |
40 | |
41 =head2 Reporting Bugs | |
42 | |
43 Report bugs to the Bioperl bug tracking system to help us keep track | |
44 the bugs and their resolution. Bug reports can be submitted via email | |
45 or the web: | |
46 | |
47 bioperl-bugs@bio.perl.org | |
48 http://bugzilla.bioperl.org/ | |
49 | |
50 =head1 AUTHOR - Jason Stajich | |
51 | |
52 Email jason@bioperl.org | |
53 | |
54 =head1 APPENDIX | |
55 | |
56 The rest of the documentation details each of the object | |
57 methods. Internal methods are usually preceded with a _ | |
58 | |
59 =cut | |
60 | |
61 # Let the code begin... | |
62 | |
63 package Bio::LocationI; | |
64 use vars qw(@ISA $coord_policy); | |
65 use strict; | |
66 | |
67 use Bio::RangeI; | |
68 use Bio::Location::WidestCoordPolicy; | |
69 use Carp; | |
70 | |
71 @ISA = qw(Bio::RangeI); | |
72 | |
73 BEGIN { | |
74 $coord_policy = Bio::Location::WidestCoordPolicy->new(); | |
75 } | |
76 | |
77 =head2 location_type | |
78 | |
79 Title : location_type | |
80 Usage : my $location_type = $location->location_type(); | |
81 Function: Get location type encoded as text | |
82 Returns : string ('EXACT', 'WITHIN', 'BETWEEN') | |
83 Args : none | |
84 | |
85 =cut | |
86 | |
87 sub location_type { | |
88 my ($self,@args) = @_; | |
89 $self->throw_not_implemented(); | |
90 } | |
91 | |
92 =head2 start | |
93 | |
94 Title : start | |
95 Usage : $start = $location->start(); | |
96 Function: Get the start coordinate of this location as defined by | |
97 the currently active coordinate computation policy. In | |
98 simple cases, this will return the same number as | |
99 min_start() and max_start(), in more ambiguous cases like | |
100 fuzzy locations the number may be equal to one or neither | |
101 of both. | |
102 | |
103 We override this here from RangeI in order to delegate | |
104 'get' to a L<Bio::Location::CoordinatePolicy> implementing | |
105 object. Implementing classes may also wish to provide | |
106 'set' functionality, in which case they *must* override | |
107 this method. The implementation provided here will throw | |
108 an exception if called with arguments. | |
109 | |
110 Returns : A positive integer value. | |
111 Args : none | |
112 | |
113 See L<Bio::Location::CoordinatePolicy> for more information | |
114 | |
115 =cut | |
116 | |
117 sub start { | |
118 my ($self,@args) = @_; | |
119 | |
120 # throw if @args means that we don't support updating information | |
121 # in the interface but will delegate to the coordinate policy object | |
122 # for interpreting the 'start' value | |
123 | |
124 $self->throw_not_implemented if @args; | |
125 return $self->coordinate_policy()->start($self); | |
126 } | |
127 | |
128 =head2 end | |
129 | |
130 Title : end | |
131 Usage : $end = $location->end(); | |
132 Function: Get the end coordinate of this location as defined by the | |
133 currently active coordinate computation policy. In simple | |
134 cases, this will return the same number as min_end() and | |
135 max_end(), in more ambiguous cases like fuzzy locations | |
136 the number may be equal to one or neither of both. | |
137 | |
138 We override this here from Bio::RangeI in order to delegate | |
139 'get' to a L<Bio::Location::CoordinatePolicy> implementing | |
140 object. Implementing classes may also wish to provide | |
141 'set' functionality, in which case they *must* override | |
142 this method. The implementation provided here will throw | |
143 an exception if called with arguments. | |
144 | |
145 Returns : A positive integer value. | |
146 Args : none | |
147 | |
148 See L<Bio::Location::CoordinatePolicy> and L<Bio::RangeI> for more | |
149 information | |
150 | |
151 =cut | |
152 | |
153 sub end { | |
154 my ($self,@args) = @_; | |
155 | |
156 # throw if @args means that we don't support updating information | |
157 # in the interface but will delegate to the coordinate policy object | |
158 # for interpreting the 'end' value | |
159 $self->throw_not_implemented if @args; | |
160 return $self->coordinate_policy()->end($self); | |
161 } | |
162 | |
163 =head2 min_start | |
164 | |
165 Title : min_start | |
166 Usage : my $minstart = $location->min_start(); | |
167 Function: Get minimum starting point of feature. | |
168 | |
169 Note that an implementation must not call start() in this method. | |
170 | |
171 Returns : integer or undef if no minimum starting point. | |
172 Args : none | |
173 | |
174 =cut | |
175 | |
176 sub min_start { | |
177 my($self) = @_; | |
178 $self->throw_not_implemented(); | |
179 } | |
180 | |
181 =head2 max_start | |
182 | |
183 Title : max_start | |
184 Usage : my $maxstart = $location->max_start(); | |
185 Function: Get maximum starting point of feature. | |
186 | |
187 Note that an implementation must not call start() in this method | |
188 unless start() is overridden such as not to delegate to the | |
189 coordinate computation policy object. | |
190 | |
191 Returns : integer or undef if no maximum starting point. | |
192 Args : none | |
193 | |
194 =cut | |
195 | |
196 sub max_start { | |
197 my($self) = @_; | |
198 $self->throw_not_implemented(); | |
199 } | |
200 | |
201 =head2 start_pos_type | |
202 | |
203 Title : start_pos_type | |
204 Usage : my $start_pos_type = $location->start_pos_type(); | |
205 Function: Get start position type encoded as text | |
206 | |
207 Known valid values are 'BEFORE' (<5..100), 'AFTER' (>5..100), | |
208 'EXACT' (5..100), 'WITHIN' ((5.10)..100), 'BETWEEN', (5^6), with | |
209 their meaning best explained by their GenBank/EMBL location string | |
210 encoding in brackets. | |
211 | |
212 Returns : string ('BEFORE', 'AFTER', 'EXACT','WITHIN', 'BETWEEN') | |
213 Args : none | |
214 | |
215 =cut | |
216 | |
217 sub start_pos_type { | |
218 my($self) = @_; | |
219 $self->throw_not_implemented(); | |
220 } | |
221 | |
222 =head2 min_end | |
223 | |
224 Title : min_end | |
225 Usage : my $minend = $location->min_end(); | |
226 Function: Get minimum ending point of feature. | |
227 | |
228 Note that an implementation must not call end() in this method | |
229 unless end() is overridden such as not to delegate to the | |
230 coordinate computation policy object. | |
231 | |
232 Returns : integer or undef if no minimum ending point. | |
233 Args : none | |
234 | |
235 =cut | |
236 | |
237 sub min_end { | |
238 my($self) = @_; | |
239 $self->throw_not_implemented(); | |
240 } | |
241 | |
242 =head2 max_end | |
243 | |
244 Title : max_end | |
245 Usage : my $maxend = $location->max_end(); | |
246 Function: Get maximum ending point of feature. | |
247 | |
248 Note that an implementation must not call end() in this method | |
249 unless end() is overridden such as not to delegate to the | |
250 coordinate computation policy object. | |
251 | |
252 Returns : integer or undef if no maximum ending point. | |
253 Args : none | |
254 | |
255 =cut | |
256 | |
257 sub max_end { | |
258 my($self) = @_; | |
259 $self->throw_not_implemented(); | |
260 } | |
261 | |
262 =head2 end_pos_type | |
263 | |
264 Title : end_pos_type | |
265 Usage : my $end_pos_type = $location->end_pos_type(); | |
266 Function: Get end position encoded as text. | |
267 | |
268 Known valid values are 'BEFORE' (5..<100), 'AFTER' (5..>100), | |
269 'EXACT' (5..100), 'WITHIN' (5..(90.100)), 'BETWEEN', (5^6), with | |
270 their meaning best explained by their GenBank/EMBL location string | |
271 encoding in brackets. | |
272 | |
273 Returns : string ('BEFORE', 'AFTER', 'EXACT','WITHIN', 'BETWEEN') | |
274 Args : none | |
275 | |
276 =cut | |
277 | |
278 sub end_pos_type { | |
279 my($self) = @_; | |
280 $self->throw_not_implemented(); | |
281 } | |
282 | |
283 =head2 seq_id | |
284 | |
285 Title : seq_id | |
286 Usage : my $seqid = $location->seq_id(); | |
287 Function: Get/Set seq_id that location refers to | |
288 Returns : seq_id (a string) | |
289 Args : [optional] seq_id value to set | |
290 | |
291 =cut | |
292 | |
293 sub seq_id { | |
294 my ($self, $seqid) = @_; | |
295 if( defined $seqid ) { | |
296 $self->{'_seqid'} = $seqid; | |
297 } | |
298 return $self->{'_seqid'}; | |
299 } | |
300 | |
301 =head2 is_remote | |
302 | |
303 Title : is_remote | |
304 Usage : $is_remote_loc = $loc->is_remote() | |
305 Function: Whether or not a location is a remote location. | |
306 | |
307 A location is said to be remote if it is on a different | |
308 'object' than the object which 'has' this | |
309 location. Typically, features on a sequence will sometimes | |
310 have a remote location, which means that the location of | |
311 the feature is on a different sequence than the one that is | |
312 attached to the feature. In such a case, $loc->seq_id will | |
313 be different from $feat->seq_id (usually they will be the | |
314 same). | |
315 | |
316 While this may sound weird, it reflects the location of the | |
317 kind of AB18375:450-900 which can be found in GenBank/EMBL | |
318 feature tables. | |
319 | |
320 Example : | |
321 Returns : TRUE if the location is a remote location, and FALSE otherwise | |
322 Args : | |
323 | |
324 | |
325 =cut | |
326 | |
327 sub is_remote{ | |
328 shift->throw_not_implemented(); | |
329 } | |
330 | |
331 =head2 coordinate_policy | |
332 | |
333 Title : coordinate_policy | |
334 Usage : $policy = $location->coordinate_policy(); | |
335 $location->coordinate_policy($mypolicy); # set may not be possible | |
336 Function: Get the coordinate computing policy employed by this object. | |
337 | |
338 See L<Bio::Location::CoordinatePolicyI> for documentation | |
339 about the policy object and its use. | |
340 | |
341 The interface *does not* require implementing classes to | |
342 accept setting of a different policy. The implementation | |
343 provided here does, however, allow to do so. | |
344 | |
345 Implementors of this interface are expected to initialize | |
346 every new instance with a | |
347 L<Bio::Location::CoordinatePolicyI> object. The | |
348 implementation provided here will return a default policy | |
349 object if none has been set yet. To change this default | |
350 policy object call this method as a class method with an | |
351 appropriate argument. Note that in this case only | |
352 subsequently created Location objects will be affected. | |
353 | |
354 Returns : A L<Bio::Location::CoordinatePolicyI> implementing object. | |
355 Args : On set, a L<Bio::Location::CoordinatePolicyI> implementing object. | |
356 | |
357 See L<Bio::Location::CoordinatePolicyI> for more information | |
358 | |
359 | |
360 =cut | |
361 | |
362 sub coordinate_policy { | |
363 my ($self, $policy) = @_; | |
364 | |
365 if(defined($policy)) { | |
366 if(! $policy->isa('Bio::Location::CoordinatePolicyI')) { | |
367 $self->throw("Object of class ".ref($policy)." does not implement". | |
368 " Bio::Location::CoordinatePolicyI"); | |
369 } | |
370 if(ref($self)) { | |
371 $self->{'_coordpolicy'} = $policy; | |
372 } else { | |
373 # called as class method | |
374 $coord_policy = $policy; | |
375 } | |
376 } | |
377 return (ref($self) && exists($self->{'_coordpolicy'}) ? | |
378 $self->{'_coordpolicy'} : $coord_policy); | |
379 } | |
380 | |
381 =head2 to_FTstring | |
382 | |
383 Title : to_FTstring | |
384 Usage : my $locstr = $location->to_FTstring() | |
385 Function: returns the FeatureTable string of this location | |
386 Returns : string | |
387 Args : none | |
388 | |
389 =cut | |
390 | |
391 sub to_FTstring { | |
392 my($self) = @_; | |
393 $self->throw_not_implemented(); | |
394 } | |
395 | |
396 =head2 each_Location | |
397 | |
398 Title : each_Location | |
399 Usage : @locations = $locObject->each_Location($order); | |
400 Function: Conserved function call across Location:: modules - will | |
401 return an array containing the component Location(s) in | |
402 that object, regardless if the calling object is itself a | |
403 single location or one containing sublocations. | |
404 Returns : an array of Bio::LocationI implementing objects | |
405 Args : Optional sort order to be passed to sub_Location() for Splits | |
406 | |
407 =cut | |
408 | |
409 sub each_Location { | |
410 my ($self,@args) = @_; | |
411 $self->throw_not_implemented(); | |
412 } | |
413 | |
414 1; | |
415 |