comparison variant_effect_predictor/Bio/EnsEMBL/Variation/StructuralVariation.pm @ 0:1f6dce3d34e0

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author mahtabm
date Thu, 11 Apr 2013 02:01:53 -0400
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1 =head1 LICENSE
2
3 Copyright (c) 1999-2012 The European Bioinformatics Institute and
4 Genome Research Limited. All rights reserved.
5
6 This software is distributed under a modified Apache license.
7 For license details, please see
8
9 http://www.ensembl.org/info/about/code_licence.html
10
11 =head1 CONTACT
12
13 Please email comments or questions to the public Ensembl
14 developers list at <dev@ensembl.org>.
15
16 Questions may also be sent to the Ensembl help desk at
17 <helpdesk@ensembl.org>.
18
19 =cut
20
21 # Ensembl module for Bio::EnsEMBL::Variation::StructuralVariation
22 #
23 # Copyright (c) 2004 Ensembl
24 #
25
26
27 =head1 NAME
28
29 Bio::EnsEMBL::Variation::StructuralVariation - Ensembl representation of a structural variation.
30
31 =head1 SYNOPSIS
32
33 # Structural variation representing a CNV
34 $sv = Bio::EnsEMBL::Variation::StructuralVariation->new
35 (-variation_name => 'esv25480',
36 -class_so_term => 'structural_variant',
37 -source => 'DGVa',
38 -source_description => 'Database of Genomic Variants Archive',
39 -study_name => 'estd20',
40 -study_description => 'Conrad 2009 "Origins and functional impact of copy number variation in the human genome." PMID:19812545 [remapped from build NCBI36]',
41 -study_url => 'ftp://ftp.ebi.ac.uk/pub/databases/dgva/estd20_Conrad_et_al_2009',
42 -external_reference => 'pubmed/19812545');
43
44 ...
45
46 print $sv->name(), ":", $sv->var_class();
47
48 =head1 DESCRIPTION
49
50 This is a class representing a structural variation from the
51 ensembl-variation database. A structural variant may have a copy number variation, a tandem duplication,
52 an inversion of the sequence or others structural variations.
53
54 The position of a StructuralVariation object on the Genome is represented
55 by the <Bio::EnsEMBL::Variation::StructuralVariationFeature> class.
56
57 =head1 METHODS
58
59 =cut
60
61 use strict;
62 use warnings;
63
64 package Bio::EnsEMBL::Variation::StructuralVariation;
65
66 use Bio::EnsEMBL::Variation::BaseStructuralVariation;
67
68 our @ISA = ('Bio::EnsEMBL::Variation::BaseStructuralVariation');
69
70
71 sub new {
72 my $caller = shift;
73 my $class = ref($caller) || $caller;
74
75 my $self = Bio::EnsEMBL::Variation::BaseStructuralVariation->new(@_);
76 return(bless($self, $class));
77 }
78
79 =head2 get_all_SupportingStructuralVariants
80
81 Example : $sv->get_all_SupportingStructuralVariants();
82 Description : Retrieves all SupportingStructuralVariation associated with this structural variation.
83 Return empty list if there are none.
84 Returntype : reference to list of Bio::EnsEMBL::Variation::SupportingStructuralVariation objects
85 Exceptions : None
86 Caller : general
87 Status : At Risk
88
89 =cut
90
91 sub get_all_SupportingStructuralVariants {
92 my $self = shift;
93
94 if (defined ($self->{'adaptor'})){
95 my $ssv_adaptor = $self->{'adaptor'}->db()->get_SupportingStructuralVariationAdaptor();
96 return $ssv_adaptor->fetch_all_by_StructuralVariation($self);
97 }
98 warn("No variation database attached");
99 return [];
100 }
101
102
103 =head2 summary_as_hash
104
105 Example : $sv_summary = $sv->summary_as_hash();
106 Description : Retrieves a textual summary of this StructuralVariation object.
107 Returns : hashref of descriptive strings
108
109 =cut
110
111 sub summary_as_hash {
112 my $self = shift;
113 my %summary;
114 $summary{'display_id'} = $self->display_id;
115 $summary{'study_name'} = $self->study_name;
116 $summary{'study_description'} = $self->study_description;
117 $summary{'class'} = $self->var_class;
118 return \%summary;
119
120 }
121
122 1;