comparison variant_effect_predictor/Bio/AlignIO/mase.pm @ 0:1f6dce3d34e0

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date Thu, 11 Apr 2013 02:01:53 -0400
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1 # $Id: mase.pm,v 1.9 2002/10/22 07:38:25 lapp Exp $
2 #
3 # BioPerl module for Bio::AlignIO::mase
4
5 # based on the Bio::SeqIO::mase module
6 # by Ewan Birney <birney@sanger.ac.uk>
7 # and Lincoln Stein <lstein@cshl.org>
8 #
9 # and the SimpleAlign.pm module of Ewan Birney
10 #
11 # Copyright Peter Schattner
12 #
13 # You may distribute this module under the same terms as perl itself
14 # _history
15 # September 5, 2000
16 # POD documentation - main docs before the code
17
18 =head1 NAME
19
20 Bio::AlignIO::mase - mase sequence input/output stream
21
22 =head1 SYNOPSIS
23
24 Do not use this module directly. Use it via the L<Bio::AlignIO> class.
25
26 =head1 DESCRIPTION
27
28 This object can transform L<Bio::Align::AlignI> objects to and from mase flat
29 file databases.
30
31 =head1 FEEDBACK
32
33 =head2 Reporting Bugs
34
35 Report bugs to the Bioperl bug tracking system to help us keep track
36 the bugs and their resolution.
37 Bug reports can be submitted via email or the web:
38
39 bioperl-bugs@bio.perl.org
40 http://bugzilla.bioperl.org/
41
42 =head1 AUTHORS - Peter Schattner
43
44 Email: schattner@alum.mit.edu
45
46
47 =head1 APPENDIX
48
49 The rest of the documentation details each of the object
50 methods. Internal methods are usually preceded with a _
51
52 =cut
53
54 # Let the code begin...
55
56 package Bio::AlignIO::mase;
57 use vars qw(@ISA);
58 use strict;
59
60 use Bio::AlignIO;
61
62 @ISA = qw(Bio::AlignIO);
63
64
65 =head2 next_aln
66
67 Title : next_aln
68 Usage : $aln = $stream->next_aln()
69 Function: returns the next alignment in the stream.
70 Returns : L<Bio::Align::AlignI> object
71 Args : NONE
72
73 =cut
74
75 sub next_aln {
76 my $self = shift;
77 my $entry;
78 my $name;
79 my $start;
80 my $end;
81 my $seq;
82 my $add;
83 my $count = 0;
84 my $seq_residues;
85
86 my $aln = Bio::SimpleAlign->new(-source => 'mase');
87
88
89 while( $entry = $self->_readline) {
90 $entry =~ /^;/ && next;
91 if( $entry =~ /^(\S+)\/(\d+)-(\d+)/ ) {
92 $name = $1;
93 $start = $2;
94 $end = $3;
95 } else {
96 $entry =~ s/\s//g;
97 $name = $entry;
98 $end = -1;
99 }
100
101 $seq = "";
102
103 while( $entry = $self->_readline) {
104 $entry =~ /^;/ && last;
105 $entry =~ s/[^A-Za-z\.\-]//g;
106 $seq .= $entry;
107 }
108 if( $end == -1) {
109 $start = 1;
110
111 $seq_residues = $seq;
112 $seq_residues =~ s/\W//g;
113 $end = length($seq_residues);
114 }
115
116 $add = new Bio::LocatableSeq('-seq'=>$seq,
117 '-id'=>$name,
118 '-start'=>$start,
119 '-end'=>$end,
120 );
121
122
123 $aln->add_seq($add);
124
125
126 # If $end <= 0, we have either reached the end of
127 # file in <> or we have encountered some other error
128 #
129 if ($end <= 0) { undef $aln;}
130
131 }
132
133 return $aln;
134 }
135
136
137
138 =head2 write_aln
139
140 Title : write_aln
141 Usage : $stream->write_aln(@aln)
142 Function: writes the $aln object into the stream in mase format ###Not yet implemented!###
143 Returns : 1 for success and 0 for error
144 Args : L<Bio::Align::AlignI> object
145
146
147 =cut
148
149 sub write_aln {
150 my ($self,@aln) = @_;
151
152 $self->throw("Sorry: mase-format output, not yet implemented! /n");
153 }
154
155 1;