comparison variant_effect_predictor/Bio/EnsEMBL/UnmappedObject.pm @ 0:2bc9b66ada89 draft default tip

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=head1 LICENSE

  Copyright (c) 1999-2012 The European Bioinformatics Institute and
  Genome Research Limited.  All rights reserved.

  This software is distributed under a modified Apache license.
  For license details, please see

    http://www.ensembl.org/info/about/code_licence.html

=head1 CONTACT

  Please email comments or questions to the public Ensembl
  developers list at <[e-mail]>.

  Questions may also be sent to the Ensembl help desk at
  <[e-mail]>.

=cut

=head1 NAME

Bio:EnsEMBL::UnmappedObject - A object representing why a particular entity
was NOT mapped to the ensembl.

=head1 SYNOPSIS

  use Bio::EnsEMBL::UnmappedObject;

  my $uo = Bio::EnsEMBL::UnmappedObject->new(
    -type           => 'xref',
    -analysis       => $analysis,
    -external_db_id => 4100,
    -identifier     => "Q12345",
    -query_score    => 45.5,
    -target_score   => 29.2,
    -ensembl_id     => 122346,
    -ensembl_type   => "Translation",
    -summary        => "match failed for exonerate",
    -full_desc      => "match failed for the xref exonerate run "
      . "as match was below threshold of 90"
  );

=head1 DESCRIPTION

UnmappedObjects represent entities NOT mapped to ensembl. Therefore this
should help users to find out why certain accessions etc can not be
found.

=head1 METHODS

=cut



package Bio::EnsEMBL::UnmappedObject;

use strict;
use warnings;

use Bio::EnsEMBL::Utils::Argument qw(rearrange);
use Bio::EnsEMBL::Utils::Exception qw(throw);
use Bio::EnsEMBL::Storable;

use vars qw(@ISA);

@ISA = qw(Bio::EnsEMBL::Storable);


=head2 new

  Arg [TYPE]           : the type of mapping i.e. 'xref','cDNA' 
  Arg [ANALYSIS]       : Analysis object. 
  Arg [EXTERNAL_DB_ID] : id for the external db id this identifier is from
  Arg [IDENTIFIER]     : name of the identifier i.e. accession
  Arg [QUERY_SCORE]    : (optional) The query score
  Arg [TARGET_SCORE]   : (optional) The target score
  Arg [SUMMARY]        : The summary reason for not mapping.
  Arg [FULL_DESC]      : The Full description of why it did not map.
  Arg [ENSEMBL_ID]     : (optional) internal ensembl id for the best match
  Arg [ENSEMBL_OBJECT_TYPE] : (optional) the type of object for the best match
  Example              : see SYNOPSIS
  Returntype           : Bio::EnsEMBL::UnmappedObject
  Exceptions           : If any of the none optional args are missing
  Caller               : general
  Status               : At Risk

=cut

sub new {
  my $caller = shift;

  #allow constructor to be called as class or object method
  my $class = ref($caller) || $caller;



  my ($dbID, $unmapped_reason_id, $type, $analysis, $ex_db_id, $identifier, 
      $query_score, $target_score, $summary, $full_desc,
      $ensembl_id, $ensembl_object_type, $adaptor ) = 
    rearrange([qw(UNMAPPED_OBJECT_ID UNMAPPED_REASON_ID TYPE ANALYSIS 
		  EXTERNAL_DB_ID IDENTIFIER QUERY_SCORE TARGET_SCORE 
		  SUMMARY FULL_DESC ENSEMBL_ID ENSEMBL_OBJECT_TYPE ADAPTOR)], @_);

  my $self = $class->SUPER::new(@_);
  if(defined($analysis)) {
    if(!ref($analysis) || !$analysis->isa('Bio::EnsEMBL::Analysis')) {
      throw('-ANALYSIS argument must be a Bio::EnsEMBL::Analysis not '.
            $analysis);
    }
  }
  else{
    throw('-ANALYSIS argument must be given');
  }
  $self->{'analysis'} = $analysis;
  $self->{'dbID'} = $dbID if (defined($dbID));
  $self->{'description'} = $full_desc   || throw('FULL_DESC must be given');
  $self->{'summary'} = $summary         || throw('SUMMARY must be given');
  $self->{'type'} = $type               || throw('TYPE must be given');
  $self->{'external_db_id'} = $ex_db_id;

  if (lc($type) eq "xref") {
    throw('EXTERNAL_DB_ID must be given') if ! defined $ex_db_id;
  }

  $self->{'identifier'} = $identifier   || throw('IDENTIFIER must be given');
  $self->{'query_score'} = $query_score  if(defined($query_score));
  $self->{'target_score'} = $target_score  if(defined($target_score));
  $self->{'ensembl_id'} = $ensembl_id  if(defined($ensembl_id));
  $self->{'ensembl_object_type'} = $ensembl_object_type  
    if(defined($ensembl_object_type));
  $self->{'unmapped_reason_id'} = $unmapped_reason_id 
    if(defined($unmapped_reason_id));
  $self->adaptor($adaptor)  if(defined($adaptor));
  return $self;
}

=head2 new_fast

  Arg [...]  : none
  Example    : $feature = Bio::EnsEMBL::UnmappedObject->new_fast();
  Description: Creates a new Unmapped Object.
  Returntype : Bio::EnsEMBL::UnmappedObject
  Exceptions : none
  Caller     : general
  Status     : At Risk

=cut

sub new_fast{
  my $caller = shift;

  #allow constructor to be called as class or object method
  my $class = ref($caller) || $caller;

  my $self = $class->SUPER::new(@_);

  return $self;
}

=head2 description

  Arg [1]     : (optional) * to be set to
  Example     : print $unmappedObject->description."\n";
  Description : Basic getter/setter for description
  ReturnType  : String
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub description{
  my $self = shift;

  if(@_) {
    my $des = shift;
    $self->{'description'} = $des;
  }

  return $self->{'description'};
}

=head2 summary

  Arg [1]     : (optional) summary to be set to
  Example     : print $unmappedObject->summary."\n";
  Description : Basic getter/setter for summary
  ReturnType  : String
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub summary{
  my $self = shift;

  if(@_) {
    my $des = shift;
    $self->{'summary'} = $des;
  }

  return $self->{'summary'};
}

=head2 type

  Arg [1]     : (optional) type to be set to
  Example     : print $unmappedObject->type."\n";
  Description : Basic getter/setter for type
  ReturnType  : String
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub type{
  my $self = shift;

  if(@_) {
    my $arg = shift;
    $self->{'type'} = $arg;
  }

  return $self->{'type'};
}

=head2 ensembl_object_type

  Arg [1]     : (optional) ensembl object type to be set to
  Example     : print $unmappedObject->ensembl_object_type."\n";
  Description : Basic getter/setter for ensembl object type
  ReturnType  : String
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub ensembl_object_type{
  my $self = shift;

  if(@_) {
    my $arg = shift;
    $self->{'ensembl_object_type'} = $arg;
  }

  return $self->{'ensembl_object_type'};
}

=head2 ensembl_id

  Arg [1]     : (optional) ensembl id to be set to
  Example     : print $unmappedObject->ensembl_id."\n";
  Description : Basic getter/setter for ensembl id
  ReturnType  : String
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub ensembl_id{
  my $self = shift;

  if(@_) {
    my $arg = shift;
    $self->{'ensembl_id'} = $arg;
  }

  return $self->{'ensembl_id'};
}

=head2 external_db_id

  Arg [1]     : (optional) external_db_id to be set to
  Example     : print $unmappedObject->external_db_id."\n";
  Description : Basic getter/setter for external_db_id
  ReturnType  : int
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub external_db_id{
  my $self = shift;

  if(@_) {
    my $arg = shift;
    $self->{'external_db_id'} = $arg;
  }
  
  return $self->{'external_db_id'};
}

=head2 external_db_name

  Example     : print $unmappedObject->external_db_name()."\n";
  Description : Basic getter for external_db_name
  ReturnType  : int
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub external_db_name{
  my $self = shift;

  my $handle = $self->adaptor;
  if(defined($handle) and defined($self->{'external_db_id'})){
    my $sth = $handle->prepare("select db_name from external_db where external_db_id = ".$self->{'external_db_id'});
    $sth->execute();
    my $name;
    $sth->bind_columns(\$name);
    $sth->fetch();
    return $name;
  }
  return "";
}


sub stable_id{
  my ($self) = shift;
  
  my $handle = $self->adaptor;
  if(defined($handle)){
    my $sql = "select stable_id from ".lc($self->{'ensembl_object_type'})." where ".
      lc($self->{'ensembl_object_type'})."_id = ".
	$self->{'ensembl_id'};
    my $sth = $handle->prepare($sql);
    $sth->execute();
    my $name;
    $sth->bind_columns(\$name);
    $sth->fetch();
    return $name;
  }
  return "";
}
					     
 #  my $adaptor;
#  if($self->{'ensembl_object_type'} eq  "Transcript"){
#    $adaptor= $self->adaptor->db->get_TranscriptAdaptor();
#  }
#  elsif($self->{'ensembl_object_type'} eq  "Translation"){
#    $adaptor= $self->adaptor->db->get_TranslationAdaptor();
#  }
#  elsif($self->{'ensembl_object_type'} eq  "Gene"){
#    $adaptor= $self->adaptor->db->get_GeneAdaptor();
#  } 
#  else{
#    return undef;
#  }
#  my $object = $adaptor->fetch_by_dbID($self->{'ensembl_id'});
#  if(defined($object)){
#    return $object->stable_id;
#  }
#  else{
#    return undef;
#  }
#}

 
=head2 identifier

  Arg [1]     : (optional) identifier to be set to
  Example     : print $unmappedObject->identifier."\n";
  Description : Basic getter/setter for identifier
  ReturnType  : String
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub identifier{
  my $self = shift;

  if(@_) {
    my $arg = shift;
    $self->{'identifier'} = $arg;
  }

  return $self->{'identifier'};
}

=head2 query_score

  Arg [1]     : (optional) query_score to be set to
  Example     : print $unmappedObject->query_score."\n";
  Description : Basic getter/setter for query_score
  ReturnType  : float
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub query_score{
  my $self = shift;

  if(@_) {
    my $arg = shift;
    $self->{'query_score'} = $arg;
  }

  return $self->{'query_score'};
}

=head2 target_score

  Arg [1]     : (optional) target_score to be set to
  Example     : print $unmappedObject->target_score."\n";
  Description : Basic getter/setter for target_score
  ReturnType  : float
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub target_score{
  my $self = shift;

  if(@_) {
    my $arg = shift;
    $self->{'target_score'} = $arg;
  }

  return $self->{'target_score'};
}

=head2 unmapped_reason_id

  Arg [1]     : (optional) unmapped_reason_id to be set to
  Example     : print $unmappedObject->unmapped_reason_id."\n";
  Description : Basic getter/setter for unmapped_reason_id
  ReturnType  : int
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub unmapped_reason_id{
  my $self = shift;

  if(@_) {
    my $arg = shift;
    $self->{'unmapped_reason_id'} = $arg;
  }

  return $self->{'unmapped_reason_id'};
}

=head2 analysis

  Arg [1]     : (optional) analysis to be set to
  Example     : print $unmappedObject->analysis->logic_name."\n";
  Description : Basic getter/setter for analysis
  ReturnType  : Bio::EnsEMBL::Analysis
  Exceptions  : none
  Caller      : general
  Status      : At Risk

=cut

sub analysis {
  my $self = shift;

  if(@_) {
    my $an = shift;
    if(defined($an) && (!ref($an) || !$an->isa('Bio::EnsEMBL::Analysis'))) {
      throw('analysis argument must be a Bio::EnsEMBL::Analysis');
    }
    $self->{'analysis'} = $an;
  }

  return $self->{'analysis'};
}

1;