# HG changeset patch # User John Chilton # Date 1368133044 18000 # Node ID 81b8283bc5546f1ec9fbc2ff7ddcbaf65113214b # Parent f2f9a648c6fbb092fc2dde580dd1912076ee74da Add help section to iquant tool. diff -r f2f9a648c6fb -r 81b8283bc554 iquant.xml --- a/iquant.xml Thu May 09 10:51:12 2013 -0500 +++ b/iquant.xml Thu May 09 15:57:24 2013 -0500 @@ -51,5 +51,19 @@ +**What it does** + +iQuant is a tool that performs tag based isobaric quantification by implementing a technique assigning collective reporter ion intensity-based weights to each peptide abundance ratio and calculating a protein's weighted average abundance ratio and p-value. + +iQuant requires identification results from an upstream identification pipeline along with XML peak lists for the data (mzXML is well supported and an mzML option has been provided for testing). + +------ + +**Citation** + +For the underlying tool, please cite ``Onsongo G, Stone MD, Van Riper SK, Chilton J, Wu B, Higgins L, Lund TC, Carlis JV, Griffin TJ, 2010. LTQ-iQuant: A freely available software pipeline for automated and accurate protein quantification of isobaric tagged peptide data from LTQ instruments. Proteomics. 10(19). doi: 10.1002/pmic.201000189.`` + +If you use this tool in Galaxy, please cite Chilton J, et al. https://bitbucket.org/galaxyp/galaxyp-toolshed-iquant +