# HG changeset patch # User jbrayet # Date 1453372239 18000 # Node ID f2b22de83c6c69a4a6c46d60c1e821a309a7e155 # Parent ba7684ab500988146a07c54beaae5ceb8bef5707 Uploaded diff -r ba7684ab5009 -r f2b22de83c6c peakSplitter_wrapper.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/peakSplitter_wrapper.xml Thu Jan 21 05:30:39 2016 -0500 @@ -0,0 +1,23 @@ + + Subdivides peak regions containing more than one site of signal enrichment + + institutcuriengsintegration/peaksplitter:1.0 + + peakSplitter_wrapper.sh -p $peaksIn -w $wigIn -o $subPeaks -h ${GALAXY_DATA_INDEX_DIR} + + + + + + + + + + +**What it does** + +PeakSplitter accurately subdivides experimentally-derived peak regions containing more than one site of signal enrichment, optionally retrieving genomic DNA sequences corresponding to subpeak summit regions. Local maxima are identified in the peak region, heights of neighboring maxima are compared, and the lowest value is multiplied by a user-adjustable parameter to yield the minimum read depth required to separate peaks. + +This facilitates more detailed analysis of individual subpeaks, which is particularly useful for discerning individual binding sites that may be present in aggregate peak regions and in obtaining candidate sequences for motif analysis. + + \ No newline at end of file