Mercurial > repos > iuc > macs2
diff readme.rst @ 16:d9a0a017896a draft
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author | iuc |
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date | Sat, 15 Feb 2014 15:41:04 -0500 |
parents | 9c157b556c33 |
children | 35a80f8dda5c |
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--- a/readme.rst Fri Jan 24 11:18:29 2014 -0500 +++ b/readme.rst Sat Feb 15 15:41:04 2014 -0500 @@ -1,60 +1,61 @@ ======================== -Galaxy wrapper for MACS2 +Galaxy deeptools wrapper ======================== -With the improvement of sequencing techniques, chromatin immunoprecipitation -followed by high throughput sequencing (ChIP-Seq) is getting popular to study -genome-wide protein-DNA interactions. To address the lack of powerful ChIP-Seq -analysis method, we present a novel algorithm, named Model-based Analysis of -ChIP-Seq (MACS), for identifying transcript factor binding sites. MACS captures -the influence of genome complexity to evaluate the significance of enriched ChIP -regions, and MACS improves the spatial resolution of binding sites through -combining the information of both sequencing tag position and orientation. -MACS can be easily used for ChIP-Seq data alone, or with control sample with the increase of specificity. +deepTools are user-friendly tools for the normalization and visualization of +deep-sequencing data. +They address the challenge of visualizing the large amounts of data that are now +routinely generated from sequencing centers in a meaningful way. +To do so, deepTools contain useful routines to process the mapped reads data +through removal of duplicates and different filtering options to create coverage +files in standard bedGraph and bigWig file formats. deepTools allow the creation +of normalized coverage files or the comparison between two files +(for example, treatment and control). Finally, using such normalized and +standardized files, multiple visualizations can be created to identify +enrichments with functional annotations of the genome. +For a gallery of images that can be produced and a description +of the tools see our poster_. + +.. _poster: http://f1000.com/posters/browse/summary/1094053 + +deeptools is developed under here: + + https://github.com/fidelram/deepTools + +For support, questions, or feature requests contact: deeptools@googlegroups.com -============ -Installation -============ +======== +Citation +======== -It is recommended to install this wrapper via the `Galaxy Tool Shed`. - -.. _`Galaxy Tool Shed`: http://toolshed.g2.bx.psu.edu/view/modencode-dcc/macs2 +deeptools are currently under review. In the meantime please refere to https://github.com/fidelram/deepTools. ======= History ======= -- v2.0.10.1: Initial public release -- v2.0.10.3: add "broad peaks" options - -==================== -Detailed description -==================== - -View the original MACS2 documentation: https://github.com/taoliu/MACS/blob/master/README.rst +- v1.0: Initial public release -=============================== -Wrapper Licence (MIT/BSD style) -=============================== +Licence (MIT) +============= + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: -Permission to use, copy, modify, and distribute this software and its -documentation with or without modifications and for any purpose and -without fee is hereby granted, provided that any copyright notices -appear in all copies and that both those copyright notices and this -permission notice appear in supporting documentation, and that the -names of the contributors or copyright holders not be used in -advertising or publicity pertaining to distribution of the software -without specific prior permission. +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. -THE CONTRIBUTORS AND COPYRIGHT HOLDERS OF THIS SOFTWARE DISCLAIM ALL -WARRANTIES WITH REGARD TO THIS SOFTWARE, INCLUDING ALL IMPLIED -WARRANTIES OF MERCHANTABILITY AND FITNESS, IN NO EVENT SHALL THE -CONTRIBUTORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY SPECIAL, INDIRECT -OR CONSEQUENTIAL DAMAGES OR ANY DAMAGES WHATSOEVER RESULTING FROM LOSS -OF USE, DATA OR PROFITS, WHETHER IN AN ACTION OF CONTRACT, NEGLIGENCE -OR OTHER TORTIOUS ACTION, ARISING OUT OF OR IN CONNECTION WITH THE USE -OR PERFORMANCE OF THIS SOFTWARE. - +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE.