Mercurial > repos > iuc > macs2
diff readme.rst @ 17:35a80f8dda5c draft
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| author | iuc |
|---|---|
| date | Sat, 15 Feb 2014 15:43:39 -0500 |
| parents | d9a0a017896a |
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--- a/readme.rst Sat Feb 15 15:41:04 2014 -0500 +++ b/readme.rst Sat Feb 15 15:43:39 2014 -0500 @@ -1,61 +1,60 @@ ======================== -Galaxy deeptools wrapper +Galaxy wrapper for MACS2 ======================== -deepTools are user-friendly tools for the normalization and visualization of -deep-sequencing data. -They address the challenge of visualizing the large amounts of data that are now -routinely generated from sequencing centers in a meaningful way. -To do so, deepTools contain useful routines to process the mapped reads data -through removal of duplicates and different filtering options to create coverage -files in standard bedGraph and bigWig file formats. deepTools allow the creation -of normalized coverage files or the comparison between two files -(for example, treatment and control). Finally, using such normalized and -standardized files, multiple visualizations can be created to identify -enrichments with functional annotations of the genome. -For a gallery of images that can be produced and a description -of the tools see our poster_. - -.. _poster: http://f1000.com/posters/browse/summary/1094053 - -deeptools is developed under here: - - https://github.com/fidelram/deepTools - -For support, questions, or feature requests contact: deeptools@googlegroups.com +With the improvement of sequencing techniques, chromatin immunoprecipitation +followed by high throughput sequencing (ChIP-Seq) is getting popular to study +genome-wide protein-DNA interactions. To address the lack of powerful ChIP-Seq +analysis method, we present a novel algorithm, named Model-based Analysis of +ChIP-Seq (MACS), for identifying transcript factor binding sites. MACS captures +the influence of genome complexity to evaluate the significance of enriched ChIP +regions, and MACS improves the spatial resolution of binding sites through +combining the information of both sequencing tag position and orientation. +MACS can be easily used for ChIP-Seq data alone, or with control sample with the increase of specificity. -======== -Citation -======== +============ +Installation +============ -deeptools are currently under review. In the meantime please refere to https://github.com/fidelram/deepTools. +It is recommended to install this wrapper via the `Galaxy Tool Shed`. + +.. _`Galaxy Tool Shed`: http://toolshed.g2.bx.psu.edu/view/modencode-dcc/macs2 ======= History ======= +- v2.0.10.1: Initial public release +- v2.0.10.3: add "broad peaks" options -- v1.0: Initial public release + +==================== +Detailed description +==================== + +View the original MACS2 documentation: https://github.com/taoliu/MACS/blob/master/README.rst -Licence (MIT) -============= - -Permission is hereby granted, free of charge, to any person obtaining a copy -of this software and associated documentation files (the "Software"), to deal -in the Software without restriction, including without limitation the rights -to use, copy, modify, merge, publish, distribute, sublicense, and/or sell -copies of the Software, and to permit persons to whom the Software is -furnished to do so, subject to the following conditions: +=============================== +Wrapper Licence (MIT/BSD style) +=============================== -The above copyright notice and this permission notice shall be included in -all copies or substantial portions of the Software. +Permission to use, copy, modify, and distribute this software and its +documentation with or without modifications and for any purpose and +without fee is hereby granted, provided that any copyright notices +appear in all copies and that both those copyright notices and this +permission notice appear in supporting documentation, and that the +names of the contributors or copyright holders not be used in +advertising or publicity pertaining to distribution of the software +without specific prior permission. -THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR -IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, -FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE -AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER -LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, -OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN -THE SOFTWARE. +THE CONTRIBUTORS AND COPYRIGHT HOLDERS OF THIS SOFTWARE DISCLAIM ALL +WARRANTIES WITH REGARD TO THIS SOFTWARE, INCLUDING ALL IMPLIED +WARRANTIES OF MERCHANTABILITY AND FITNESS, IN NO EVENT SHALL THE +CONTRIBUTORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY SPECIAL, INDIRECT +OR CONSEQUENTIAL DAMAGES OR ANY DAMAGES WHATSOEVER RESULTING FROM LOSS +OF USE, DATA OR PROFITS, WHETHER IN AN ACTION OF CONTRACT, NEGLIGENCE +OR OTHER TORTIOUS ACTION, ARISING OUT OF OR IN CONNECTION WITH THE USE +OR PERFORMANCE OF THIS SOFTWARE. +
