# HG changeset patch # User iuc # Date 1630399439 0 # Node ID 405dd85a9408a4caf533f49891a3dc8319f364a1 # Parent ffeedf9b8dce8e14357ad89a9a45b73b7f68c211 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit e0d4688a59e6eeba33adcfe803ac43d0bc2863e7" diff -r ffeedf9b8dce -r 405dd85a9408 hmmbuild.xml.orig --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/hmmbuild.xml.orig Tue Aug 31 08:43:59 2021 +0000 @@ -0,0 +1,114 @@ + +<<<<<<< HEAD + + Build a profile HMM from an input multiple alignment + + macros.xml + + + + + Build a profile HMM from an input multiple alignment + + + macros.xml + + + + >>>>>> c37d72558 (add more bio.tool IDs) +hmmbuild + +#if $hmmname: + -n '$hmmname' +#end if + +@FORMAT_SELECTOR@ +@MCSS@ +@ARSWS@ +@AEEWS@ +@PRIOR@ +@HSSI@ +@EVAL_CALIB@ + +@CPU@ +@SEED@ + +@LENGTHS@ +#if str($maxinsertlen): + --maxinsertlen $maxinsertlen +#end if + +'$hmmout' +'$msafile' + ]]> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + build a profile HMM and save +it to a new file . + +@HELP_PRE_OTH@ + +@FORMAT_SELECTOR_HELP@ +@MCSS_HELP@ +@ARSWS_HELP@ +@AEEWS_HELP@ +@PRIOR_HELP@ +@HSSI_HELP@ +@EVAL_CALIB_HELP@ +@SEED_HELP@ +@LENGTHS_HELP@ + +@ATTRIBUTION@ + ]]> + + diff -r ffeedf9b8dce -r 405dd85a9408 hmmscan.xml.orig --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/hmmscan.xml.orig Tue Aug 31 08:43:59 2021 +0000 @@ -0,0 +1,93 @@ + +<<<<<<< HEAD + + search protein sequence(s) against a protein profile database + + macros.xml + + + + + search protein sequence(s) against a protein profile database + + + macros.xml + + + + >>>>>> c37d72558 (add more bio.tool IDs) +@INPUTHMMCHOICE@ +hmmscan + +@OFORMAT_WITH_OPTS@ +@THRESHOLDS@ +@CUT@ +@ACCEL_HEUR@ +@ADV_OPTS@ +@CPU@ +@SEED@ + +'$input_hmm_filename' +'$seqfile' +> '$output' + ]]> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + , use that query sequence to search the +target database of profiles in , and output ranked lists of the profiles +with the most significant matches to the sequence. + +@HELP_PRE_OTH@ + +@OFORMAT_WITH_OPTS_HELP@ +@THRESHOLDS_HELP@ +@CUT_HELP@ +@ACCEL_HEUR_HELP@ +@ADV_OPTS_HELP@ +@SEED_HELP@ + +@ATTRIBUTION@ + ]]> + + diff -r ffeedf9b8dce -r 405dd85a9408 hmmsearch.xml --- a/hmmsearch.xml Wed Jul 21 14:06:36 2021 +0000 +++ b/hmmsearch.xml Tue Aug 31 08:43:59 2021 +0000 @@ -1,6 +1,7 @@ search profile(s) against a sequence database + macros.xml diff -r ffeedf9b8dce -r 405dd85a9408 hmmsearch.xml.orig --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/hmmsearch.xml.orig Tue Aug 31 08:43:59 2021 +0000 @@ -0,0 +1,102 @@ + +<<<<<<< HEAD + + search profile(s) against a sequence database + + macros.xml + + + + + search profile(s) against a sequence database + + + macros.xml + + + + >>>>>> c37d72558 (add more bio.tool IDs) +hmmsearch + +@OFORMAT_WITH_OPTS@ +@THRESHOLDS@ +@CUT@ +@ACCEL_HEUR@ +@ADV_OPTS@ +@CPU@ +@SEED@ + +'$hmmfile' +'$seqdb' +> '$output' + ]]> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + , use that query profile to search the target +database of sequences in , and output ranked lists of the sequences with +the most significant matches to the profile. To build profiles from multiple +alignments, see hmmbuild. + +@HELP_PRE_OTH@ + +@OFORMAT_WITH_OPTS_HELP@ +@THRESHOLDS_HELP@ +@CUT_HELP@ +@ACCEL_HEUR_HELP@ +@ADV_OPTS_HELP@ +@SEED_HELP@ + +@ATTRIBUTION@ + ]]> + + diff -r ffeedf9b8dce -r 405dd85a9408 jackhmmer.xml.orig --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/jackhmmer.xml.orig Tue Aug 31 08:43:59 2021 +0000 @@ -0,0 +1,116 @@ + +<<<<<<< HEAD + + iteratively search a protein sequence against a protein database (PSIBLAST-like) + + macros.xml + + + + + iteratively search a protein sequence against a protein database (PSIBLAST-like) + + + macros.xml + + + + >>>>>> c37d72558 (add more bio.tool IDs) +jackhmmer +-N $N +@OFORMAT_WITH_OPTS@ +@HSSI@ +@THRESHOLDS@ +@ACCEL_HEUR@ +@ARSWS@ +@AEEWS@ +@PRIOR@ + +@EVAL_CALIB@ +@ADV_OPTS@ +@CPU@ +@SEED@ + +'$seqfile' +'$seqdb' +> '$output' + ]]> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + against the +target sequence(s) in . The first iteration is identical to a phmmer +search. For the next iteration, a multiple alignment of the query together +with all target sequences satisfying inclusion thresholds is assembled, a +profile is constructed from this alignment (identical to using hmmbuild on the +alignment), and profile search of the is done (identical to an +hmmsearch with the profile). + + +@HELP_PRE_OTH@ + +@OFORMAT_WITH_OPTS_HELP_NOPFAM@ +@HSSI_HELP@ +@THRESHOLDS_HELP@ +@ACCEL_HEUR_HELP@ +@ARSWS_HELP@ +@AEEWS_HELP@ +@PRIOR_HELP@ +@EVAL_CALIB_HELP@ +@ADV_OPTS_HELP@ +@SEED_HELP@ + +@ATTRIBUTION@ + ]]> + + diff -r ffeedf9b8dce -r 405dd85a9408 macros.xml --- a/macros.xml Wed Jul 21 14:06:36 2021 +0000 +++ b/macros.xml Tue Aug 31 08:43:59 2021 +0000 @@ -6,6 +6,11 @@ + + + hmmer3 + + 3.3.2 diff -r ffeedf9b8dce -r 405dd85a9408 macros.xml.orig --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/macros.xml.orig Tue Aug 31 08:43:59 2021 +0000 @@ -0,0 +1,1126 @@ + + + + + hmmer + + + +<<<<<<< HEAD + + + gemini + + +======= + + + hmmer3 + + +>>>>>>> 5f65381bd (fix id of hmmer3) + 3.3.2 + + + + + + + + + + + +-E $E +--domE $domE + +#if str($T): + -T $T +#end if + +#if str($domT): + --domT $domT +#end if + +#if str($incE): + --incE $incE +#end if + +#if str($incdomE): + --incdomE $incdomE +#end if + +#if str($incT): + --incT $incT +#end if + +#if str($incdomT): + --incdomT $incdomT +#end if + + + + + + + + + + + + + + +-E $E + +#if str($T): + -T $T +#end if + +#if str($incE): + --incE $incE +#end if + +#if str($incT): + --incT $incT +#end if + + + + + + + + + + +$max +--F1 $F1 +--F2 $F2 +--F3 $F3 +$nobias + + + + + + + + + + +--EmL $EmL +--EmN $EmN +--EvL $EvL +--EvN $EvN +--EfL $EfL +--EfN $EfN +--Eft $Eft + + + + + + + + + + + + +#if $oformat: + #for o in str($oformat).split(','): + --$o '$getVar($o, 'MISSING_OUTPUT'+$o)' + #end for +#end if +$acc $noali $notextw + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + oformat and 'tblout' in oformat + + + + + + + oformat and 'domtblout' in oformat + + + + + + + + oformat and 'pfamtblout' in oformat + + + + + + + oformat and 'dfamtblout' in oformat + + + oformat and 'aliscoresout' in oformat + + + + + + + + + + + + + + + + + + + + + + +#if $hssi.hssi_select == "singlemx": + --popen $hssi.popen + --pextend $hssi.pextend +#end if + + + + + + + + + + + + + + + + + + + + --cpu \$addthreads + + + --seed $seed + + + + + + + + +$nonull2 + +#if str($Z): + -Z $Z +#end if + +#if str($domZ): + --domZ $domZ +#end if + + + + + + + + + $input_format_select + + + + + + + + + + + + + + + +$arsws.arsws_select + +#if $arsws.arsws_select == "--wblosum": + --wid $arsws.wid +#end if + + + + + + + + + + + + + + + + + + + + + + + + + +#if $aeews.aeews_select != "": +--$aeews.aeews_select + #if $aeews.aeews_select == "eent": + --eset $aeews.eset + --ere $aeews.ere + --esigma $aeews.esigma + #elif $aeews.aeews_select == "eclust": + --eset $aeews.eset + --eid $aeews.eid + #end if +#end if + + + + + + + + + + + + + + + + + + + + + + + + + + +$cut_ga +$cut_nc +$cut_tc + + + + + + + +--$mcs.model_construction_strategy_select + +#if $mcs.model_construction_strategy_select == "fast": + --symfrac $mcs.symfrac +#end if +#if str($fragthresh) + --fragthresh $fragthresh +#end if + + + + + + + + + + + + + + + + +$aps_select + + + + + + + + + + + 10.1093/nar/gkr367 + + + +#if str($w_beta): + --w_beta $w_beta +#end if + +#if str($w_length): + --w_length $w_length +#end if + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + would pass 5% of the comparisons, making a search more sensitive +but slower. Setting the threshold to ≥ 1.0 (--F1 99 for example) assures +that all comparisons will pass. Shutting off the MSV filter may be +worthwhile if you want to make sure you don’t miss comparisons that have +a lot of scattered insertions and deletions. Alternatively, the --max +option causes the MSV filter step (and all other filter steps) to be +bypassed. + +The MSV bit score is calculated as a log-odds score using the null model +for comparison. No correction for a biased composition or repetitive +sequence is done at this stage. For comparisons involving biased +sequences and/or profiles, more than 2% of comparisons will pass the MSV +filter. At the end of search output, there is a line like: + + Passed MSV filter: 107917 (0.020272); expected 106468.8 (0.02) + +which tells you how many and what fraction of comparisons passed the MSV +filter, versus how many (and what fraction) were expected. + +**Viterbi filter** + +The sequence is now aligned to the profile using a fast Viterbi algorithm for +optimal gapped alignment. + +This Viterbi implementation is specialized for speed. It is implemented in +8-way parallel SIMD vector instructions, using reduced precision scores that +have been scaled to 16-bit integers. Only one row of the dynamic programming +matrix is stored, so the routine only recovers the score, not the optimal +alignment itself. The reduced representation has limited range; local alignment +scores will not underflow, but high scoring comparisons can overflow and return +infinity, in which case they automatically pass the filter. + +The final Viterbi filter bit score is then computed using the appropriate null +model log likelihood (by default the biased composition filter model score, or +if the biased filter is off, just the null model score). If the P-value of this +score passes the Viterbi filter threshold, the sequence passes on to the next +step of the pipeline. + +The --F2 option controls the P-value threshold for passing the Viterbi +filter score. The default is 0.001. The --max option bypasses all filters in +the pipeline. At the end of a search output, you will see a line like: + + Passed Vit filter: 2207 (0.00443803); expected 497.3 (0.001) + +which tells you how many and what fraction of comparisons passed the Viterbi +filter, versus how many were expected. + +**Forward filter/parser** + +The sequence is now aligned to the profile using the full Forward algorithm, +which calculates the likelihood of the target sequence given the profile, +summed over the ensemble of all possible alignments. + +This is a specialized time- and memory-efficient Forward implementation called +the “Forward parser”. It is implemented in 4-way parallel SIMD vector +instructions, in full precision (32-bit floating point). It stores just enough +information that, in combination with the results of the Backward parser +(below), posterior probabilities of start and stop points of alignments +(domains) can be calculated in the domain definition step (below), although the +detailed alignments themselves cannot be. + +The Forward filter bit score is calculated by correcting this score using the +appropriate null model log likelihood (by default the biased composition filter +model score, or if the biased filter is off, just the null model score). If the +P-value of this bit score passes the Forward filter threshold, the sequence +passes on to the next step of the pipeline. + +The bias filter score has no further effect in the pipeline. It is only used in +filter stages. It has no effect on final reported bit scores or P-values. +Biased composition compensation for final bit scores is done by a more complex +domain-specific algorithm, described below. + +The --F3 option controls the P-value threshold for passing the Forward +filter score. The default is 1e-5. The --max option bypasses all filters in the +pipeline. At the end of a search output, you will see a line like: + + Passed Fwd filter: 1076 (0.00216371); expected 5.0 (1e-05) + +which tells you how many and what fraction of comparisons passed the Forward +filter, versus how many were expected. + +**Bias Filter Options** + +The --max option bypasses all filters in the pipeline, including the bias +filter. + +The --nobias option turns off (bypasses) the biased composition filter. The +simple null model is used as a null hypothesis for MSV and in subsequent filter +steps. The biased composition filter step compromises a small amount of +sensitivity. Though it is good to have it on by default, you may want to shut +it off if you know you will have no problem with biased composition hits. + + +**Advanced Documentation** + +A more detailed look at the internals of the various filter pipelines was +posted on the `developer's blog `__. +The information posted there may be useful to those who are struggling with +poor-scoring sequences. +]]> + , for the +purposes of per-domain conditional E-value calculations, rather than the number +of targets that passed the reporting thresholds. + +**Z** + +Assert that the total number of targets in your searches is , for the +purposes of per-sequence E-value calculations, rather than the actual number of +targets seen. +]]> + . + +**--ere** + +Set the minimum relative entropy/position target to . Requires --eent. Default +depends on the sequence alphabet. For protein sequences, it is 0.59 bits/position; +for nucleotide sequences, it is 0.45 bits/position. + +**--esigma** + +Sets the minimum relative entropy contributed by an entire model alignment, over +its whole length. This has the effect of making short models have higher relative +entropy per position than --ere alone would give. The default is 45.0 bits. + +**--eid** + +Sets the fractional pairwise identity cutoff used by single linkage clustering +with the --eclust option. The default is 0.62. +]]> + + + and the per-domain threshold These act as if +-T --incT --domT --incdomT has been applied specifically using +each model’s curated thresholds. + +**--cut_ga** + +Use the GA (gathering) bit scores in the model to set per-sequence (GA1) and +per-domain (GA2) reporting and inclusion thresholds. GA thresholds are +generally considered to be the reliable curated thresholds defining family +membership; for example, in Pfam, these thresholds define what gets included in +Pfam Full alignments based on searches with Pfam Seed models. + +**--cut_nc** + +Use the NC (noise cutoff) bit score thresholds in the model to set +per-sequence (NC1) and per-domain (NC2) reporting and inclusion thresholds. NC +thresholds are generally considered to be the score of the highest-scoring +known false positive. + +**--cut_tc** + +Use the NC (trusted cutoff) bit score thresholds in the model to set +per-sequence (TC1) and per-domain (TC2) reporting and inclusion thresholds. TC +thresholds are generally considered to be the score of the lowest-scoring known +true positive that is above all known false positives. +]]> + + + + +**Gap Extend (--pextend)** + +Set the gap extend probability for a single sequence query model to . + + +**--mx/--mxfile** + +These options are not currently supported +]]> + = W is less than . The default is 1e-7. + + +**Model instance length upper bound (--w length)** + +Override the model instance length upper bound, W, which is otherwise +controlled by --w beta. It should be larger than the model length. The value of +W is used deep in the acceleration pipeline, and modest changes are not +expected to impact results (though larger values of W do lead to longer run +time). + +]]> + = symfrac of residues +as opposed to gaps. (See below for the --symfrac option.) This is the default. + +**--hand** + +Define consensus columns in next profile using reference annotation to the multiple +alignment. This allows you to define any consensus columns you like. + + +**--symfrac** + +Define the residue fraction threshold necessary to define a consensus column +when using the --fast option. The default is 0.5. The symbol fraction in each +column is calculated after taking relative sequence weighting into account, and +ignoring gap characters corresponding to ends of sequence fragments (as opposed +to internal insertions/deletions). Setting this to 0.0 means that every +alignment column will be assigned as consensus, which may be useful in some +cases. Setting it to 1.0 means that only columns that include 0 gaps (internal +insertions/deletions) will be assigned as consensus. + +**--fragthresh** + +We only want to count terminal gaps as deletions if the aligned sequence is +known to be full-length, not if it is a fragment (for instance, because only +part of it was sequenced). HMMER uses a simple rule to infer fragments: if the +sequence length L is less than or equal to a fraction times the alignment +length in columns, then the sequence is handled as a fragment. The default is +0.5. Setting --fragthresh0 will define no (nonempty) sequence as a fragment; +you might want to do this if you know you’ve got a carefully curated alignment +of full-length sequences. Setting --fragthresh1 will define all sequences as +fragments; you might want to do this if you know your alignment is entirely +composed of fragments, such as translated short reads in metagenomic shotgun +data. + +]]> + + + + + , an integer >= 0. If is nonzero, +any stochastic simulations will be reproducible; the same command will give the +same results. If is 0, the random number generator is seeded arbitrarily, +and stochastic simulations will vary from run to run of the same command. + +]]> + . The +default is 10.0, meaning that on average, about 10 false positives will be +reported per query, so you can see the top of the noise and decide for yourself +if it’s really noise. + +**Bit score (-T)** + +Instead of thresholding per-profile output on E-value, instead report target profiles +with a bit score of >= . + +**domain E-value (--domE)** + +In the per-domain output, for target profiles that have already satisfied the +per-profile reporting threshold, report individual domains with a conditional +E-value of <= . The default is 10.0. A conditional E-value means the +expected number of additional false positive domains in the smaller search +space of those comparisons that already satisfied the per-profile reporting +threshold (and thus must have at least one homologous domain already). + +**domain Bit scores (--domT)** + +Instead of thresholding per-domain output on E-value, instead report domains +with a bit score of >= . + +Options for Inclusion Thresholds +-------------------------------- + +Inclusion thresholds are stricter than reporting thresholds. Inclusion +thresholds control which hits are considered to be reliable enough to be +included in an output alignment or a subsequent search round. In hmmscan, which +does not have any alignment output (like hmmsearch or phmmer) nor any iterative +search steps (like jackhmmer), inclusion thresholds have little effect. They +only affect what domains get marked as significant (!) or questionable (?) in +domain output. + +**E-value of per target inclusion threshold** + +Use an E-value of <= as the per-target inclusion threshold. The default is +0.01, meaning that on average, about 1 false positive would be expected in +every 100 searches with different query sequences. + +**Bit score of per target inclusion threshold** + +Instead of using E-values for setting the inclusion threshold, instead use a +bit score of >= as the per-target inclusion threshold. It would be unusual +to use bit score thresholds with hmmscan, because you don’t expect a single +score threshold to work for different profiles; different profiles have +slightly different expected score distributions. + +**domain E-value per target inclusion treshold** + +Use a conditional E-value of <= as the per-domain inclusion threshold, in +targets that have already satisfied the overall per-target inclusion threshold. + +**domain Bit score per target inclusion treshold** + +Instead of using E-values, instead use a bit score of >= as the per-domain +inclusion threshold. As with --incT above, it would be unusual to use a single +bit score threshold in hmmscan. + +]]> + . The +default is 10.0, meaning that on average, about 10 false positives will be +reported per query, so you can see the top of the noise and decide for yourself +if it’s really noise. + +**Bit score (-T)** + +Instead of thresholding per-profile output on E-value, instead report target profiles +with a bit score of >= . + +Options for Inclusion Thresholds +-------------------------------- + +Inclusion thresholds are stricter than reporting thresholds. Inclusion +thresholds control which hits are considered to be reliable enough to be +included in an output alignment or a subsequent search round. In hmmscan, which +does not have any alignment output (like hmmsearch or phmmer) nor any iterative +search steps (like jackhmmer), inclusion thresholds have little effect. They +only affect what domains get marked as significant (!) or questionable (?) in +domain output. + +**E-value of per target inclusion threshold** + +Use an E-value of <= as the per-target inclusion threshold. The default is +0.01, meaning that on average, about 1 false positive would be expected in +every 100 searches with different query sequences. + +**Bit score of per target inclusion threshold** + +Instead of using E-values for setting the inclusion threshold, instead use a +bit score of >= as the per-target inclusion threshold. It would be unusual +to use bit score thresholds with hmmscan, because you don’t expect a single +score threshold to work for different profiles; different profiles have +slightly different expected score distributions. + +]]> + + + + diff -r ffeedf9b8dce -r 405dd85a9408 nhmmer.xml.orig --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/nhmmer.xml.orig Tue Aug 31 08:43:59 2021 +0000 @@ -0,0 +1,115 @@ + +<<<<<<< HEAD + + search a DNA model or alignment against a DNA database (BLASTN-like) + + macros.xml + + + + + search a DNA model or alignment against a DNA database (BLASTN-like) + + + macros.xml + + + + >>>>>> c37d72558 (add more bio.tool IDs) +nhmmer + +@OFORMAT_WITH_OPTS@ +@HSSI@ +@THRESHOLDS_NODOM@ +@CUT@ +@ACCEL_HEUR@ +@FORMAT_SELECTOR@ +@ADV_OPTS@ +@LENGTHS@ +@CPU@ +@SEED@ + +'$hmmfile' +'$seqfile' +> '$output' + ]]> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + , use that query to search the +target database of sequences in , and output a ranked list of the hits +with the most significant matches to the query. A query may be either a profile +model built using hmmbuild, a sequence alignment, or a single sequence. +Sequence based queries can be in a number of formats (see --qformat), and can +typically be autodetected. Note that only Stockholm format supports the use of +multiple sequence-based queries. + +@HELP_PRE_OTH@ + +@OFORMAT_WITH_OPTS_N_HELP@ +@HSSI_HELP@ +@THRESHOLDS_NODOM_HELP@ +@CUT_HELP@ +@ACCEL_HEUR_HELP@ +@FORMAT_SELECTOR_HELP@ +@ADV_OPTS_HELP@ +@LENGTHS_HELP@ +@SEED_HELP@ + +@ATTRIBUTION@ + ]]> + + diff -r ffeedf9b8dce -r 405dd85a9408 nhmmscan.xml.orig --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/nhmmscan.xml.orig Tue Aug 31 08:43:59 2021 +0000 @@ -0,0 +1,113 @@ + +<<<<<<< HEAD + + search DNA sequence(s) against a DNA profile database + + macros.xml + + + + + search DNA sequence(s) against a DNA profile database + + + macros.xml + + + + >>>>>> c37d72558 (add more bio.tool IDs) +@INPUTHMMCHOICE@ +nhmmscan + +@OFORMAT_WITH_OPTS@ +@THRESHOLDS_NODOM@ +@CUT@ +@ACCEL_HEUR@ +--B1 $B1 +--B2 $B2 +--B3 $B3 + +@ADV_OPTS@ +@LENGTHS@ +@CPU@ +@SEED@ + +'$input_hmm_filename' +'$seqfile' +> '$output' + ]]> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + , use that query sequence to +search the target database of profiles in , and output ranked lists of +the profiles with the most significant matches to the sequence. + +The may contain more than one query sequence. It can be in FASTA +format, or several other common sequence file formats (genbank, embl, and +uniprot, among others), or in alignment file formats (stockholm, aligned fasta, +and others). See the --qformat option for a complete list. + +@HELP_PRE_OTH@ + +@OFORMAT_WITH_OPTS_N_HELP@ +@THRESHOLDS_NODOM_HELP@ +@CUT_HELP@ +@ACCEL_HEUR_HELP@ +@BIAS_COMP_HELP@ +@ADV_OPTS_HELP@ +@LENGTHS_HELP@ +@SEED_HELP@ + + +@ATTRIBUTION@ +]]> + + diff -r ffeedf9b8dce -r 405dd85a9408 phmmer.xml.orig --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/phmmer.xml.orig Tue Aug 31 08:43:59 2021 +0000 @@ -0,0 +1,107 @@ + +<<<<<<< HEAD + + search a protein sequence against a protein database (BLASTP-like) + + macros.xml + + + + + search a protein sequence against a protein database (BLASTP-like) + + + macros.xml + + + + >>>>>> c37d72558 (add more bio.tool IDs) +phmmer + +@OFORMAT_WITH_OPTS@ +@HSSI@ +@THRESHOLDS@ +@ACCEL_HEUR@ +@EVAL_CALIB@ +@ADV_OPTS@ + +@CPU@ +@SEED@ + +'$seqfile' +'$seqdb' +> '$output' + ]]> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + , use that sequence to +search the target database of sequences in , and output ranked lists of +the sequences with the most significant matches to the query. + + +@HELP_PRE_OTH@ + +@OFORMAT_WITH_OPTS_HELP@ +@HSSI_HELP@ +@THRESHOLDS_HELP@ +@ACCEL_HEUR_HELP@ +@EVAL_CALIB_HELP@ +@ADV_OPTS_HELP@ +@SEED_HELP@ + +@ATTRIBUTION@ + ]]> + +