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| author | galaxyp |
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| date | Wed, 20 Jun 2018 14:20:53 -0400 |
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GENE UNIPROT REACTION_STID REACTION_DISPLAY_NAME PATHWAY_STID PATHWAY_DISPLAY_NAME TOP_LEVEL_PATHWAY_STID TOP_LEVEL_PATHWAY_DISPLAY_NAME CFTR P13569 R-HSA-1454916 The ABCC family mediates organic anion transport R-HSA-382556 ABC-family proteins mediated transport R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-1454916 The ABCC family mediates organic anion transport R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-383190 HCO3- transport through ion channel R-HSA-382556 ABC-family proteins mediated transport R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-383190 HCO3- transport through ion channel R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-5678863 CFTR transports Cl- from cytosol to extracellular region R-HSA-382556 ABC-family proteins mediated transport R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-5678863 CFTR transports Cl- from cytosol to extracellular region R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane R-HSA-194315 Signaling by Rho GTPases R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane R-HSA-195258 RHO GTPase Effectors R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane R-HSA-5627083 RHO GTPases regulate CFTR trafficking R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol R-HSA-382556 ABC-family proteins mediated transport R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR R-HSA-382556 ABC-family proteins mediated transport R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation R-HSA-382556 ABC-family proteins mediated transport R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CFTR P13569 R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region R-HSA-1643685 Disease R-HSA-1643685 Disease CFTR P13569 R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region R-HSA-5619115 Disorders of transmembrane transporters R-HSA-1643685 Disease CFTR P13569 R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region R-HSA-5619084 ABC transporter disorders R-HSA-1643685 Disease CFTR P13569 R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region R-HSA-5678895 Defective CFTR causes cystic fibrosis R-HSA-1643685 Disease CFTR P13569 R-HSA-5679000 Ivacaftor binds CFTR G551D R-HSA-1643685 Disease R-HSA-1643685 Disease CFTR P13569 R-HSA-5679000 Ivacaftor binds CFTR G551D R-HSA-5619115 Disorders of transmembrane transporters R-HSA-1643685 Disease CFTR P13569 R-HSA-5679000 Ivacaftor binds CFTR G551D R-HSA-5619084 ABC transporter disorders R-HSA-1643685 Disease CFTR P13569 R-HSA-5679000 Ivacaftor binds CFTR G551D R-HSA-5678895 Defective CFTR causes cystic fibrosis R-HSA-1643685 Disease CFTR P13569 R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol R-HSA-1643685 Disease R-HSA-1643685 Disease CFTR P13569 R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol R-HSA-5619115 Disorders of transmembrane transporters R-HSA-1643685 Disease CFTR P13569 R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol R-HSA-5619084 ABC transporter disorders R-HSA-1643685 Disease CFTR P13569 R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol R-HSA-5678895 Defective CFTR causes cystic fibrosis R-HSA-1643685 Disease CFTR P13569 R-HSA-8866856 RNF5 and RNF185 ubiquitinate CFTR F508del R-HSA-1643685 Disease R-HSA-1643685 Disease CFTR P13569 R-HSA-8866856 RNF5 and RNF185 ubiquitinate CFTR F508del R-HSA-5619115 Disorders of transmembrane transporters R-HSA-1643685 Disease CFTR P13569 R-HSA-8866856 RNF5 and RNF185 ubiquitinate CFTR F508del R-HSA-5619084 ABC transporter disorders R-HSA-1643685 Disease CFTR P13569 R-HSA-8866856 RNF5 and RNF185 ubiquitinate CFTR F508del R-HSA-5678895 Defective CFTR causes cystic fibrosis R-HSA-1643685 Disease CFTR P13569 R-HSA-8866857 CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation R-HSA-1643685 Disease R-HSA-1643685 Disease CFTR P13569 R-HSA-8866857 CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation R-HSA-5619115 Disorders of transmembrane transporters R-HSA-1643685 Disease CFTR P13569 R-HSA-8866857 CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation R-HSA-5619084 ABC transporter disorders R-HSA-1643685 Disease CFTR P13569 R-HSA-8866857 CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation R-HSA-5678895 Defective CFTR causes cystic fibrosis R-HSA-1643685 Disease CFTR P13569 R-HSA-6782106 USP10 deubiquitinates SNX3, CFTR R-HSA-392499 Metabolism of proteins R-HSA-392499 Metabolism of proteins CFTR P13569 R-HSA-6782106 USP10 deubiquitinates SNX3, CFTR R-HSA-597592 Post-translational protein modification R-HSA-392499 Metabolism of proteins CFTR P13569 R-HSA-6782106 USP10 deubiquitinates SNX3, CFTR R-HSA-5688426 Deubiquitination R-HSA-392499 Metabolism of proteins CFTR P13569 R-HSA-6782106 USP10 deubiquitinates SNX3, CFTR R-HSA-5689880 Ub-specific processing proteases R-HSA-392499 Metabolism of proteins CFTR P13569 R-HSA-5627072 RHOQ binds GOPC:CFTR R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627072 RHOQ binds GOPC:CFTR R-HSA-194315 Signaling by Rho GTPases R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627072 RHOQ binds GOPC:CFTR R-HSA-195258 RHO GTPase Effectors R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627072 RHOQ binds GOPC:CFTR R-HSA-5627083 RHO GTPases regulate CFTR trafficking R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627275 GOPC promotes translocation of CFTR to lysosomes R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627275 GOPC promotes translocation of CFTR to lysosomes R-HSA-194315 Signaling by Rho GTPases R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627275 GOPC promotes translocation of CFTR to lysosomes R-HSA-195258 RHO GTPase Effectors R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-5627275 GOPC promotes translocation of CFTR to lysosomes R-HSA-5627083 RHO GTPases regulate CFTR trafficking R-HSA-162582 Signal Transduction CFTR P13569 R-HSA-8868071 Clathrin recruits PIK3C2A R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868071 Clathrin recruits PIK3C2A R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868071 Clathrin recruits PIK3C2A R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868236 BAR domain proteins recruit dynamin R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868236 BAR domain proteins recruit dynamin R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868236 BAR domain proteins recruit dynamin R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8866277 AP-2 directly binds some endocytic cargo R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8866277 AP-2 directly binds some endocytic cargo R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8866277 AP-2 directly binds some endocytic cargo R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8866277 AP-2 directly binds some endocytic cargo R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport CFTR P13569 R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle R-HSA-8856828 Clathrin-mediated endocytosis R-HSA-5653656 Vesicle-mediated transport TGFB1 P01137 R-HSA-170850 Phosphorylated SMAD2/3 dissociates from TGFBR R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170850 Phosphorylated SMAD2/3 dissociates from TGFBR R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170850 Phosphorylated SMAD2/3 dissociates from TGFBR R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170850 Phosphorylated SMAD2/3 dissociates from TGFBR R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170868 Activated type I receptor phosphorylates SMAD2/3 directly R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170868 Activated type I receptor phosphorylates SMAD2/3 directly R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170868 Activated type I receptor phosphorylates SMAD2/3 directly R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170868 Activated type I receptor phosphorylates SMAD2/3 directly R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-3702186 Phosphorylated SMAD2/3 MH2 domain mutants dissociate from TGFBR R-HSA-1643685 Disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702186 Phosphorylated SMAD2/3 MH2 domain mutants dissociate from TGFBR R-HSA-5663202 Diseases of signal transduction R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702186 Phosphorylated SMAD2/3 MH2 domain mutants dissociate from TGFBR R-HSA-3304351 Signaling by TGF-beta Receptor Complex in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702186 Phosphorylated SMAD2/3 MH2 domain mutants dissociate from TGFBR R-HSA-3304349 Loss of Function of SMAD2/3 in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702186 Phosphorylated SMAD2/3 MH2 domain mutants dissociate from TGFBR R-HSA-3315487 SMAD2/3 MH2 Domain Mutants in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-170835 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170835 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170835 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170835 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170843 TGFBR2 phosphorylates TGFBR1 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170843 TGFBR2 phosphorylates TGFBR1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170843 TGFBR2 phosphorylates TGFBR1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170843 TGFBR2 phosphorylates TGFBR1 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178178 PP1 dephosphorylates TGFBR1 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178178 PP1 dephosphorylates TGFBR1 R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178178 PP1 dephosphorylates TGFBR1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178178 PP1 dephosphorylates TGFBR1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178178 PP1 dephosphorylates TGFBR1 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178189 SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178189 SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178189 SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178189 SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178189 SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2169050 SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2169050 SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2169050 SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2169050 SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2169050 SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 R-HSA-392499 Metabolism of proteins R-HSA-392499 Metabolism of proteins TGFB1 P01137 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 R-HSA-597592 Post-translational protein modification R-HSA-392499 Metabolism of proteins TGFB1 P01137 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 R-HSA-5688426 Deubiquitination R-HSA-392499 Metabolism of proteins TGFB1 P01137 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 R-HSA-5689603 UCH proteinases R-HSA-392499 Metabolism of proteins TGFB1 P01137 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179293 UCHL5 binds SMAD7 in complex with ubiquitinated TGFBR1 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179293 UCHL5 binds SMAD7 in complex with ubiquitinated TGFBR1 R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179293 UCHL5 binds SMAD7 in complex with ubiquitinated TGFBR1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179293 UCHL5 binds SMAD7 in complex with ubiquitinated TGFBR1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2179293 UCHL5 binds SMAD7 in complex with ubiquitinated TGFBR1 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2128994 STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2128994 STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2128994 STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2128994 STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2128994 STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2127562 STRAP binds phosphorylated TGF-beta receptor complex R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2127562 STRAP binds phosphorylated TGF-beta receptor complex R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2127562 STRAP binds phosphorylated TGF-beta receptor complex R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2127562 STRAP binds phosphorylated TGF-beta receptor complex R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2127562 STRAP binds phosphorylated TGF-beta receptor complex R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178218 SMAD7:SMURF complex binds to phosphorylated TGFBR1 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178218 SMAD7:SMURF complex binds to phosphorylated TGFBR1 R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178218 SMAD7:SMURF complex binds to phosphorylated TGFBR1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178218 SMAD7:SMURF complex binds to phosphorylated TGFBR1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-178218 SMAD7:SMURF complex binds to phosphorylated TGFBR1 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173483 BAMBI interferes with the interaction of type I receptor with type II receptor R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173483 BAMBI interferes with the interaction of type I receptor with type II receptor R-HSA-2173788 Downregulation of TGF-beta receptor signaling R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173483 BAMBI interferes with the interaction of type I receptor with type II receptor R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173483 BAMBI interferes with the interaction of type I receptor with type II receptor R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-173483 BAMBI interferes with the interaction of type I receptor with type II receptor R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2160935 SMURF1 ubiquitinates RHOA R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2160935 SMURF1 ubiquitinates RHOA R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2160935 SMURF1 ubiquitinates RHOA R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2160935 SMURF1 ubiquitinates RHOA R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2160932 SMURF1 binds phosphorylated PARD6A R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2160932 SMURF1 binds phosphorylated PARD6A R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2160932 SMURF1 binds phosphorylated PARD6A R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2160932 SMURF1 binds phosphorylated PARD6A R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2134532 TGFBR2 phosphorylates TGFBR1 and PARD6A R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2134532 TGFBR2 phosphorylates TGFBR1 and PARD6A R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2134532 TGFBR2 phosphorylates TGFBR1 and PARD6A R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2134532 TGFBR2 phosphorylates TGFBR1 and PARD6A R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-3713560 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 phosphorylation motif mutants R-HSA-1643685 Disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3713560 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 phosphorylation motif mutants R-HSA-5663202 Diseases of signal transduction R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3713560 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 phosphorylation motif mutants R-HSA-3304351 Signaling by TGF-beta Receptor Complex in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3713560 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 phosphorylation motif mutants R-HSA-3304349 Loss of Function of SMAD2/3 in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3713560 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 phosphorylation motif mutants R-HSA-3304356 SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702153 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 MH2 domain mutants R-HSA-1643685 Disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702153 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 MH2 domain mutants R-HSA-5663202 Diseases of signal transduction R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702153 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 MH2 domain mutants R-HSA-3304351 Signaling by TGF-beta Receptor Complex in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702153 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 MH2 domain mutants R-HSA-3304349 Loss of Function of SMAD2/3 in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702153 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 MH2 domain mutants R-HSA-3315487 SMAD2/3 MH2 Domain Mutants in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-170846 TGFBR2 recruits TGFBR1 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170846 TGFBR2 recruits TGFBR1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170846 TGFBR2 recruits TGFBR1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170846 TGFBR2 recruits TGFBR1 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2134519 TGFBR2 is recruited to tight junctions after TGF-beta stimulation R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2134519 TGFBR2 is recruited to tight junctions after TGF-beta stimulation R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2134519 TGFBR2 is recruited to tight junctions after TGF-beta stimulation R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-2134519 TGFBR2 is recruited to tight junctions after TGF-beta stimulation R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-3656484 TGFBR2 recruits TGFBR1 KD Mutants R-HSA-1643685 Disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3656484 TGFBR2 recruits TGFBR1 KD Mutants R-HSA-5663202 Diseases of signal transduction R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3656484 TGFBR2 recruits TGFBR1 KD Mutants R-HSA-3304351 Signaling by TGF-beta Receptor Complex in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3656484 TGFBR2 recruits TGFBR1 KD Mutants R-HSA-3656534 Loss of Function of TGFBR1 in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3656484 TGFBR2 recruits TGFBR1 KD Mutants R-HSA-3656532 TGFBR1 KD Mutants in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-170861 Dimeric TGF-beta-1 binds to the receptor R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170861 Dimeric TGF-beta-1 binds to the receptor R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170861 Dimeric TGF-beta-1 binds to the receptor R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170861 Dimeric TGF-beta-1 binds to the receptor R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-177107 Secretion and activation of the latent large complex of TGF-beta-1 R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-177107 Secretion and activation of the latent large complex of TGF-beta-1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-177107 Secretion and activation of the latent large complex of TGF-beta-1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-177107 Secretion and activation of the latent large complex of TGF-beta-1 R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-8951966 EP300 acetylates RUNX3 R-HSA-8878159 Transcriptional regulation by RUNX3 R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-8951966 EP300 acetylates RUNX3 R-HSA-8951936 RUNX3 regulates p14-ARF R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-8951966 EP300 acetylates RUNX3 R-HSA-73857 RNA Polymerase II Transcription R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-8951966 EP300 acetylates RUNX3 R-HSA-212436 Generic Transcription Pathway R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-8951966 EP300 acetylates RUNX3 R-HSA-74160 Gene expression (Transcription) R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-8937814 RUNX3 translocates to the nucleus R-HSA-8878159 Transcriptional regulation by RUNX3 R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-8937814 RUNX3 translocates to the nucleus R-HSA-8941858 Regulation of RUNX3 expression and activity R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-8937814 RUNX3 translocates to the nucleus R-HSA-73857 RNA Polymerase II Transcription R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-8937814 RUNX3 translocates to the nucleus R-HSA-212436 Generic Transcription Pathway R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-8937814 RUNX3 translocates to the nucleus R-HSA-74160 Gene expression (Transcription) R-HSA-74160 Gene expression (Transcription) TGFB1 P01137 R-HSA-168865 NA activation of TGF-beta R-HSA-1643685 Disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-168865 NA activation of TGF-beta R-HSA-5663205 Infectious disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-168865 NA activation of TGF-beta R-HSA-168254 Influenza Infection R-HSA-1643685 Disease TGFB1 P01137 R-HSA-168865 NA activation of TGF-beta R-HSA-168253 Host Interactions with Influenza Factors R-HSA-1643685 Disease TGFB1 P01137 R-HSA-168865 NA activation of TGF-beta R-HSA-168277 Influenza Virus Induced Apoptosis R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645786 TGFBR2 mutant dimers recruit TGFBR1 R-HSA-1643685 Disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645786 TGFBR2 mutant dimers recruit TGFBR1 R-HSA-5663202 Diseases of signal transduction R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645786 TGFBR2 mutant dimers recruit TGFBR1 R-HSA-3304351 Signaling by TGF-beta Receptor Complex in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645786 TGFBR2 mutant dimers recruit TGFBR1 R-HSA-3642278 Loss of Function of TGFBR2 in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645786 TGFBR2 mutant dimers recruit TGFBR1 R-HSA-3645790 TGFBR2 Kinase Domain Mutants in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645778 TGFB1 binds TGFBR2 KD Mutant Dimers R-HSA-1643685 Disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645778 TGFB1 binds TGFBR2 KD Mutant Dimers R-HSA-5663202 Diseases of signal transduction R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645778 TGFB1 binds TGFBR2 KD Mutant Dimers R-HSA-3304351 Signaling by TGF-beta Receptor Complex in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645778 TGFB1 binds TGFBR2 KD Mutant Dimers R-HSA-3642278 Loss of Function of TGFBR2 in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3645778 TGFB1 binds TGFBR2 KD Mutant Dimers R-HSA-3645790 TGFBR2 Kinase Domain Mutants in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3656517 TGFBR2 phosphorylates TGFBR1 KD Mutants R-HSA-1643685 Disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3656517 TGFBR2 phosphorylates TGFBR1 KD Mutants R-HSA-5663202 Diseases of signal transduction R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3656517 TGFBR2 phosphorylates TGFBR1 KD Mutants R-HSA-3304351 Signaling by TGF-beta Receptor Complex in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3656517 TGFBR2 phosphorylates TGFBR1 KD Mutants R-HSA-3656534 Loss of Function of TGFBR1 in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3656517 TGFBR2 phosphorylates TGFBR1 KD Mutants R-HSA-3656532 TGFBR1 KD Mutants in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702184 Activated type I receptor phosphorylates SMAD2/3 MH2 domain mutants directly R-HSA-1643685 Disease R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702184 Activated type I receptor phosphorylates SMAD2/3 MH2 domain mutants directly R-HSA-5663202 Diseases of signal transduction R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702184 Activated type I receptor phosphorylates SMAD2/3 MH2 domain mutants directly R-HSA-3304351 Signaling by TGF-beta Receptor Complex in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702184 Activated type I receptor phosphorylates SMAD2/3 MH2 domain mutants directly R-HSA-3304349 Loss of Function of SMAD2/3 in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-3702184 Activated type I receptor phosphorylates SMAD2/3 MH2 domain mutants directly R-HSA-3315487 SMAD2/3 MH2 Domain Mutants in Cancer R-HSA-1643685 Disease TGFB1 P01137 R-HSA-2395364 LTBP4 binds TGF-Beta-1 R-HSA-1474244 Extracellular matrix organization R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2395364 LTBP4 binds TGF-Beta-1 R-HSA-1566948 Elastic fibre formation R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2395364 LTBP4 binds TGF-Beta-1 R-HSA-2129379 Molecules associated with elastic fibres R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2395328 LTBP1, LTBP3 bind TGF-Beta R-HSA-1474244 Extracellular matrix organization R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2395328 LTBP1, LTBP3 bind TGF-Beta R-HSA-1566948 Elastic fibre formation R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2395328 LTBP1, LTBP3 bind TGF-Beta R-HSA-2129379 Molecules associated with elastic fibres R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2395320 Latent TGF-beta-1 binds integrins R-HSA-1474244 Extracellular matrix organization R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2395320 Latent TGF-beta-1 binds integrins R-HSA-1566948 Elastic fibre formation R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2395320 Latent TGF-beta-1 binds integrins R-HSA-2129379 Molecules associated with elastic fibres R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2731078 Syndecans 2, (4) bind TGFB1 R-HSA-1474244 Extracellular matrix organization R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2731078 Syndecans 2, (4) bind TGFB1 R-HSA-3000171 Non-integrin membrane-ECM interactions R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2731078 Syndecans 2, (4) bind TGFB1 R-HSA-3000170 Syndecan interactions R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2327886 SLRPs bind TGF Beta R-HSA-1474244 Extracellular matrix organization R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-2327886 SLRPs bind TGF Beta R-HSA-3000178 ECM proteoglycans R-HSA-1474244 Extracellular matrix organization TGFB1 P01137 R-HSA-481007 Exocytosis of platelet alpha granule contents R-HSA-109582 Hemostasis R-HSA-109582 Hemostasis TGFB1 P01137 R-HSA-481007 Exocytosis of platelet alpha granule contents R-HSA-76002 Platelet activation, signaling and aggregation R-HSA-109582 Hemostasis TGFB1 P01137 R-HSA-481007 Exocytosis of platelet alpha granule contents R-HSA-76005 Response to elevated platelet cytosolic Ca2+ R-HSA-109582 Hemostasis TGFB1 P01137 R-HSA-481007 Exocytosis of platelet alpha granule contents R-HSA-114608 Platelet degranulation R-HSA-109582 Hemostasis TGFB1 P01137 R-HSA-170844 Latent TGF-beta-1 is cleaved by furin R-HSA-170834 Signaling by TGF-beta Receptor Complex R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170844 Latent TGF-beta-1 is cleaved by furin R-HSA-2173789 TGF-beta receptor signaling activates SMADs R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170844 Latent TGF-beta-1 is cleaved by furin R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-170844 Latent TGF-beta-1 is cleaved by furin R-HSA-9006936 Signaling by TGF-beta family members R-HSA-162582 Signal Transduction TGFB1 P01137 R-HSA-8870732 PSGs bind proteoglycans and TGF-beta1 R-HSA-202733 Cell surface interactions at the vascular wall R-HSA-109582 Hemostasis TGFB1 P01137 R-HSA-8870732 PSGs bind proteoglycans and TGF-beta1 R-HSA-109582 Hemostasis R-HSA-109582 Hemostasis FCGR2A P12318 R-HSA-2029272 Release of PLCG from FCGR R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029272 Release of PLCG from FCGR R-HSA-2029485 Role of phospholipids in phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029272 Release of PLCG from FCGR R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029272 Release of PLCG from FCGR R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029268 Phosphorylation and activation of PLCG R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029268 Phosphorylation and activation of PLCG R-HSA-2029485 Role of phospholipids in phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029268 Phosphorylation and activation of PLCG R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029268 Phosphorylation and activation of PLCG R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029270 Recruitment of PLCgamma to membrane R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029270 Recruitment of PLCgamma to membrane R-HSA-2029485 Role of phospholipids in phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029270 Recruitment of PLCgamma to membrane R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029270 Recruitment of PLCgamma to membrane R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 R-HSA-2029485 Role of phospholipids in phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029273 PI3K binds to p-6Y-SYK R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029273 PI3K binds to p-6Y-SYK R-HSA-2029485 Role of phospholipids in phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029273 PI3K binds to p-6Y-SYK R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029273 PI3K binds to p-6Y-SYK R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029451 Activation of RAC1 by VAV R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029451 Activation of RAC1 by VAV R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029451 Activation of RAC1 by VAV R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029451 Activation of RAC1 by VAV R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029453 Phosphorylation of VAV R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029453 Phosphorylation of VAV R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029453 Phosphorylation of VAV R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029453 Phosphorylation of VAV R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029449 Phosphorylation of SYK by Src kinases R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029449 Phosphorylation of SYK by Src kinases R-HSA-2029481 FCGR activation R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029449 Phosphorylation of SYK by Src kinases R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029449 Phosphorylation of SYK by Src kinases R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029452 Recruitment of SYK to phosphorylated ITAMs R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029452 Recruitment of SYK to phosphorylated ITAMs R-HSA-2029481 FCGR activation R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029452 Recruitment of SYK to phosphorylated ITAMs R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-2029452 Recruitment of SYK to phosphorylated ITAMs R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-168256 Immune System FCGR2A P12318 R-HSA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag R-HSA-2029481 FCGR activation R-HSA-168256 Immune System FCGR2A P12318 R-HSA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag R-HSA-168256 Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-6798743 Exocytosis of secretory granule membrane proteins R-HSA-6798695 Neutrophil degranulation R-HSA-168256 Immune System FCGR2A P12318 R-HSA-6798743 Exocytosis of secretory granule membrane proteins R-HSA-168249 Innate Immune System R-HSA-168256 Immune System FCGR2A P12318 R-HSA-6798743 Exocytosis of secretory granule membrane proteins R-HSA-168256 Immune System R-HSA-168256 Immune System DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-446203 Asparagine N-linked glycosylation R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-948021 Transport to the Golgi and subsequent modification R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-199977 ER to Golgi Anterograde Transport R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-199977 ER to Golgi Anterograde Transport R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-6807878 COPI-mediated anterograde transport R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-6807878 COPI-mediated anterograde transport R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-392499 Metabolism of proteins R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-597592 Post-translational protein modification R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-446203 Asparagine N-linked glycosylation R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-948021 Transport to the Golgi and subsequent modification R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-199977 ER to Golgi Anterograde Transport R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-199977 ER to Golgi Anterograde Transport R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-6807878 COPI-mediated anterograde transport R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-6807878 COPI-mediated anterograde transport R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-392499 Metabolism of proteins R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-597592 Post-translational protein modification R-HSA-392499 Metabolism of proteins DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex R-HSA-5653656 Vesicle-mediated transport R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex R-HSA-8856688 Golgi-to-ER retrograde transport R-HSA-5653656 Vesicle-mediated transport DCTN4 Q9UJW0 R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic R-HSA-5653656 Vesicle-mediated transport SCNN1B P51168 R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules SCNN1B P51168 R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules SCNN1B P51168 R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules SCNN1B P51168 R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules SCNN1B P51168 R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules SCNN1B P51168 R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules SCNN1G P51170 R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules SCNN1G P51170 R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules SCNN1G P51170 R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules SCNN1G P51170 R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules SCNN1G P51170 R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules SCNN1G P51170 R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules SCNN1A P37088 R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules SCNN1A P37088 R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules SCNN1A P37088 R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules SCNN1A P37088 R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules SCNN1A P37088 R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules SCNN1A P37088 R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules TNFRSF1A P19438 R-HSA-83582 TRADD:TRAF2:RIP1 complex dissociates from the TNF-alpha:TNF-R1 complex. R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-83582 TRADD:TRAF2:RIP1 complex dissociates from the TNF-alpha:TNF-R1 complex. R-HSA-5357786 TNFR1-induced proapoptotic signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-83582 TRADD:TRAF2:RIP1 complex dissociates from the TNF-alpha:TNF-R1 complex. R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-83582 TRADD:TRAF2:RIP1 complex dissociates from the TNF-alpha:TNF-R1 complex. R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-83656 TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-83656 TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-83656 TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains R-HSA-5357905 Regulation of TNFR1 signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes R-HSA-5357905 Regulation of TNFR1 signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357928 CLIP3 and CYLD bind TNF signaling complex R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357928 CLIP3 and CYLD bind TNF signaling complex R-HSA-5357905 Regulation of TNFR1 signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357928 CLIP3 and CYLD bind TNF signaling complex R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357928 CLIP3 and CYLD bind TNF signaling complex R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357904 TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357904 TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357904 TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357904 TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3 recruits TAK1 complex R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3 recruits TAK1 complex R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3 recruits TAK1 complex R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3 recruits TAK1 complex R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5634221 TRAF1 binds TRAF2 within TNFR1 signaling complex R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5634221 TRAF1 binds TRAF2 within TNFR1 signaling complex R-HSA-5357905 Regulation of TNFR1 signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5634221 TRAF1 binds TRAF2 within TNFR1 signaling complex R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5634221 TRAF1 binds TRAF2 within TNFR1 signaling complex R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626953 TNF-alpha:TNFR1 binds DENN/MADD R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626953 TNF-alpha:TNFR1 binds DENN/MADD R-HSA-5357905 Regulation of TNFR1 signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626953 TNF-alpha:TNFR1 binds DENN/MADD R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626953 TNF-alpha:TNFR1 binds DENN/MADD R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626981 TNF-alpha:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626981 TNF-alpha:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 R-HSA-5626978 TNFR1-mediated ceramide production R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626981 TNF-alpha:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626981 TNF-alpha:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626982 TNF-alpha:TNFR1:NSMAF binds GNB2L1 R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626982 TNF-alpha:TNFR1:NSMAF binds GNB2L1 R-HSA-5626978 TNFR1-mediated ceramide production R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626982 TNF-alpha:TNFR1:NSMAF binds GNB2L1 R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626982 TNF-alpha:TNFR1:NSMAF binds GNB2L1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626988 TNF-alpha:TNFR1 binds NSMAF R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626988 TNF-alpha:TNFR1 binds NSMAF R-HSA-5626978 TNFR1-mediated ceramide production R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626988 TNF-alpha:TNFR1 binds NSMAF R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5626988 TNF-alpha:TNFR1 binds NSMAF R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-83660 Membrane-anchored TNF-alpha binds TNFR1 R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-83660 Membrane-anchored TNF-alpha binds TNFR1 R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-83660 Membrane-anchored TNF-alpha binds TNFR1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-3371353 Soluble TNF-alpha binds TNFR1 R-HSA-75893 TNF signaling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-3371353 Soluble TNF-alpha binds TNFR1 R-HSA-73887 Death Receptor Signalling R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-3371353 Soluble TNF-alpha binds TNFR1 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction TNFRSF1A P19438 R-HSA-5669097 LTA trimer binds TNFRSF1A,1B,14 R-HSA-168256 Immune System R-HSA-168256 Immune System TNFRSF1A P19438 R-HSA-5669097 LTA trimer binds TNFRSF1A,1B,14 R-HSA-1280215 Cytokine Signaling in Immune system R-HSA-168256 Immune System TNFRSF1A P19438 R-HSA-5669097 LTA trimer binds TNFRSF1A,1B,14 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway R-HSA-168256 Immune System TNFRSF1A P19438 R-HSA-5669097 LTA trimer binds TNFRSF1A,1B,14 R-HSA-5669034 TNFs bind their physiological receptors R-HSA-168256 Immune System CLCA4 Q14CN2 R-HSA-2744361 BESTs transport cytosolic Cl- to extracellular region R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-2744361 BESTs transport cytosolic Cl- to extracellular region R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-2744361 BESTs transport cytosolic Cl- to extracellular region R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-2684901 ANOs transport cytosolic Cl- to extracellular region R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-2684901 ANOs transport cytosolic Cl- to extracellular region R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-2684901 ANOs transport cytosolic Cl- to extracellular region R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-5333671 CLCAs self cleave R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-5333671 CLCAs self cleave R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-5333671 CLCAs self cleave R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region R-HSA-382551 Transport of small molecules R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region R-HSA-983712 Ion channel transport R-HSA-382551 Transport of small molecules CLCA4 Q14CN2 R-HSA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region R-HSA-2672351 Stimuli-sensing channels R-HSA-382551 Transport of small molecules STX1A Q16623 R-HSA-374899 Release of noradrenaline at the synapse R-HSA-181430 Norepinephrine Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-374899 Release of noradrenaline at the synapse R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-374899 Release of noradrenaline at the synapse R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-374899 Release of noradrenaline at the synapse R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-374922 Noradrenalin synaptic vesicle docking and priming R-HSA-181430 Norepinephrine Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-374922 Noradrenalin synaptic vesicle docking and priming R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-374922 Noradrenalin synaptic vesicle docking and priming R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-374922 Noradrenalin synaptic vesicle docking and priming R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-210430 release of L-Glutamate at the synapse R-HSA-210500 Glutamate Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-210430 release of L-Glutamate at the synapse R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-210430 release of L-Glutamate at the synapse R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-210430 release of L-Glutamate at the synapse R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-888589 Release of GABA at the synapse R-HSA-888590 GABA synthesis, release, reuptake and degradation R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-888589 Release of GABA at the synapse R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-888589 Release of GABA at the synapse R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-888589 Release of GABA at the synapse R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-372529 Release of acetylcholine at the synapse R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-372529 Release of acetylcholine at the synapse R-HSA-264642 Acetylcholine Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-372529 Release of acetylcholine at the synapse R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-372529 Release of acetylcholine at the synapse R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380901 Release of docked serotonin loaded synaptic vesicle R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380901 Release of docked serotonin loaded synaptic vesicle R-HSA-181429 Serotonin Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380901 Release of docked serotonin loaded synaptic vesicle R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380901 Release of docked serotonin loaded synaptic vesicle R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380869 Release of docked dopamine loaded synaptic vesicle R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380869 Release of docked dopamine loaded synaptic vesicle R-HSA-212676 Dopamine Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380869 Release of docked dopamine loaded synaptic vesicle R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380869 Release of docked dopamine loaded synaptic vesicle R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-210426 Glutamate synaptic vesicle docking and priming R-HSA-210500 Glutamate Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-210426 Glutamate synaptic vesicle docking and priming R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-210426 Glutamate synaptic vesicle docking and priming R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-210426 Glutamate synaptic vesicle docking and priming R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-917744 GABA loaded synaptic vesicle Docking and Priming R-HSA-888590 GABA synthesis, release, reuptake and degradation R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-917744 GABA loaded synaptic vesicle Docking and Priming R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-917744 GABA loaded synaptic vesicle Docking and Priming R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-917744 GABA loaded synaptic vesicle Docking and Priming R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-372505 Acetylcholine synaptic vesicle docking and priming R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-372505 Acetylcholine synaptic vesicle docking and priming R-HSA-264642 Acetylcholine Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-372505 Acetylcholine synaptic vesicle docking and priming R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-372505 Acetylcholine synaptic vesicle docking and priming R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380905 Serotonin loaded synaptic vesicle docking and priming R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380905 Serotonin loaded synaptic vesicle docking and priming R-HSA-181429 Serotonin Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380905 Serotonin loaded synaptic vesicle docking and priming R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380905 Serotonin loaded synaptic vesicle docking and priming R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380574 Dopamine synaptic vesicle docking and priming R-HSA-112310 Neurotransmitter release cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380574 Dopamine synaptic vesicle docking and priming R-HSA-212676 Dopamine Neurotransmitter Release Cycle R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380574 Dopamine synaptic vesicle docking and priming R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-380574 Dopamine synaptic vesicle docking and priming R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-449117 TXLNA (IL14) binds syntaxin1A R-HSA-168256 Immune System R-HSA-168256 Immune System STX1A Q16623 R-HSA-449117 TXLNA (IL14) binds syntaxin1A R-HSA-1280215 Cytokine Signaling in Immune system R-HSA-168256 Immune System STX1A Q16623 R-HSA-449117 TXLNA (IL14) binds syntaxin1A R-HSA-449147 Signaling by Interleukins R-HSA-168256 Immune System STX1A Q16623 R-HSA-449117 TXLNA (IL14) binds syntaxin1A R-HSA-449836 Other interleukin signaling R-HSA-168256 Immune System STX1A Q16623 R-HSA-5682802 LGI3 binds ADAM22,23,synatxin1 R-HSA-1266738 Developmental Biology R-HSA-1266738 Developmental Biology STX1A Q16623 R-HSA-5682802 LGI3 binds ADAM22,23,synatxin1 R-HSA-5682910 LGI-ADAM interactions R-HSA-1266738 Developmental Biology STX1A Q16623 R-HSA-181567 BoNT/C LC cleaves target cell STX1 R-HSA-1643685 Disease R-HSA-1643685 Disease STX1A Q16623 R-HSA-181567 BoNT/C LC cleaves target cell STX1 R-HSA-5663205 Infectious disease R-HSA-1643685 Disease STX1A Q16623 R-HSA-181567 BoNT/C LC cleaves target cell STX1 R-HSA-5339562 Uptake and actions of bacterial toxins R-HSA-1643685 Disease STX1A Q16623 R-HSA-181567 BoNT/C LC cleaves target cell STX1 R-HSA-168799 Neurotoxicity of clostridium toxins R-HSA-1643685 Disease STX1A Q16623 R-HSA-181567 BoNT/C LC cleaves target cell STX1 R-HSA-5250971 Toxicity of botulinum toxin type C (BoNT/C) R-HSA-1643685 Disease STX1A Q16623 R-HSA-6794353 NRXNs binds MUNC18 R-HSA-112316 Neuronal System R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-6794353 NRXNs binds MUNC18 R-HSA-6794362 Protein-protein interactions at synapses R-HSA-112316 Neuronal System STX1A Q16623 R-HSA-6794353 NRXNs binds MUNC18 R-HSA-6794361 Neurexins and neuroligins R-HSA-112316 Neuronal System CXCL8 P10145 R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi R-HSA-418594 G alpha (i) signalling events R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi R-HSA-372790 Signaling by GPCR R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi R-HSA-388396 GPCR downstream signalling R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi R-HSA-418594 G alpha (i) signalling events R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi R-HSA-372790 Signaling by GPCR R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi R-HSA-388396 GPCR downstream signalling R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-749454 The Ligand:GPCR:Gi complex dissociates R-HSA-418594 G alpha (i) signalling events R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-749454 The Ligand:GPCR:Gi complex dissociates R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-749454 The Ligand:GPCR:Gi complex dissociates R-HSA-372790 Signaling by GPCR R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-749454 The Ligand:GPCR:Gi complex dissociates R-HSA-388396 GPCR downstream signalling R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373813 Receptor CXCR2 binds ligands CXCL1 to 7 R-HSA-373076 Class A/1 (Rhodopsin-like receptors) R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373813 Receptor CXCR2 binds ligands CXCL1 to 7 R-HSA-375276 Peptide ligand-binding receptors R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373813 Receptor CXCR2 binds ligands CXCL1 to 7 R-HSA-380108 Chemokine receptors bind chemokines R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373813 Receptor CXCR2 binds ligands CXCL1 to 7 R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373813 Receptor CXCR2 binds ligands CXCL1 to 7 R-HSA-372790 Signaling by GPCR R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373813 Receptor CXCR2 binds ligands CXCL1 to 7 R-HSA-500792 GPCR ligand binding R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373791 Receptor CXCR1 binds CXCL6 and CXCL8 ligands R-HSA-373076 Class A/1 (Rhodopsin-like receptors) R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373791 Receptor CXCR1 binds CXCL6 and CXCL8 ligands R-HSA-375276 Peptide ligand-binding receptors R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373791 Receptor CXCR1 binds CXCL6 and CXCL8 ligands R-HSA-380108 Chemokine receptors bind chemokines R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373791 Receptor CXCR1 binds CXCL6 and CXCL8 ligands R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373791 Receptor CXCR1 binds CXCL6 and CXCL8 ligands R-HSA-372790 Signaling by GPCR R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-373791 Receptor CXCR1 binds CXCL6 and CXCL8 ligands R-HSA-500792 GPCR ligand binding R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-374251 DARC is a non-specific receptor for many chemokines R-HSA-373076 Class A/1 (Rhodopsin-like receptors) R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-374251 DARC is a non-specific receptor for many chemokines R-HSA-375276 Peptide ligand-binding receptors R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-374251 DARC is a non-specific receptor for many chemokines R-HSA-162582 Signal Transduction R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-374251 DARC is a non-specific receptor for many chemokines R-HSA-372790 Signaling by GPCR R-HSA-162582 Signal Transduction CXCL8 P10145 R-HSA-374251 DARC is a non-specific receptor for many chemokines R-HSA-500792 GPCR ligand binding R-HSA-162582 Signal Transduction