# HG changeset patch # User devteam # Date 1447090145 18000 # Node ID bbf46057ef480552060d20daf3250ba5a848e0ad planemo upload for repository https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/vcflib/vcfallelicprimitives commit 5a4e0ca9992af3a6e5ed2b533f04bb82ce761e0b diff -r 000000000000 -r bbf46057ef48 macros.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/macros.xml Mon Nov 09 12:29:05 2015 -0500 @@ -0,0 +1,28 @@ + + + + vcflib + + + + + + + + + + + +@misc{Garrison2015, + author = {Garrison, Erik}, + year = {2015}, + title = {vcflib}, + publisher = {GitHub}, + journal = {GitHub repository}, + url = {https://github.com/ekg/vcflib}, +} + + + + is a part of VCFlib toolkit developed by Erik Garrison (https://github.com/ekg/vcflib). + diff -r 000000000000 -r bbf46057ef48 test-data/vcfallelicprimitives-test1.vcf --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/vcfallelicprimitives-test1.vcf Mon Nov 09 12:29:05 2015 -0500 @@ -0,0 +1,35 @@ +##fileformat=VCFv4.0 +##fileDate=20090805 +##source=myImputationProgramV3.1 +##reference=1000GenomesPilot-NCBI36 +##phasing=partial +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##ALT= +##ALT= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +19 111 . A C 9.6 . . GT:HQ 0|0:10,10 0|0:10,10 0/1:3,3 +19 112 . A G 10 . . GT:HQ 0|0:10,10 0|0:10,10 0/1:3,3 +20 14370 rs6054257 G A 29 PASS AF=0.5;DP=14;NS=3;DB;H2 GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. +20 17330 . T A 3 q10 AF=0.017;DP=11;NS=3 GT:GQ:DP:HQ 0|0:49:3:58,50 0|1:3:5:65,3 0/0:41:3:.,. +20 1110696 . A G,T 67 PASS AF=0.333,0.667;LEN=1,1;TYPE=snp,snp;Split primitives GT 1|2 2|1 2|2 +20 1230237 . T . 47 PASS AA=T;DP=13;NS=3 GT:GQ:DP:HQ 0|0:54:.:56,60 0|0:48:4:51,51 0/0:61:2:.,. +20 1234567 . G GA,GAC 50 PASS AC=3,1;LEN=1,2;TYPE=ins,ins;Split primitives GT 0|1 0|2 1|1 +20 1235237 . T . 0 . . GT 0/0 0|0 . +X 10 . AC ATC,A 10 PASS LEN=1,1;TYPE=ins,del;Split primitives GT 0 0|2 0|1 +X 11 . C G 10 PASS LEN=1;TYPE=snp;Split primitives GT 0 0|0 0|1 diff -r 000000000000 -r bbf46057ef48 test-data/vcflib.vcf --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/vcflib.vcf Mon Nov 09 12:29:05 2015 -0500 @@ -0,0 +1,31 @@ +##fileformat=VCFv4.0 +##fileDate=20090805 +##source=myImputationProgramV3.1 +##reference=1000GenomesPilot-NCBI36 +##phasing=partial +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##ALT= +##ALT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +19 111 . A C 9.6 . . GT:HQ 0|0:10,10 0|0:10,10 0/1:3,3 +19 112 . A G 10 . . GT:HQ 0|0:10,10 0|0:10,10 0/1:3,3 +20 14370 rs6054257 G A 29 PASS NS=3;DP=14;AF=0.5;DB;H2 GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. +20 17330 . T A 3 q10 NS=3;DP=11;AF=0.017 GT:GQ:DP:HQ 0|0:49:3:58,50 0|1:3:5:65,3 0/0:41:3:.,. +20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10;AF=0.333,0.667;AA=T;DB GT:GQ:DP:HQ 1|2:21:6:23,27 2|1:2:0:18,2 2/2:35:4:.,. +20 1230237 . T . 47 PASS NS=3;DP=13;AA=T GT:GQ:DP:HQ 0|0:54:.:56,60 0|0:48:4:51,51 0/0:61:2:.,. +20 1234567 microsat1 G GA,GAC 50 PASS NS=3;DP=9;AA=G;AN=6;AC=3,1 GT:GQ:DP 0/1:.:4 0/2:17:2 1/1:40:3 +20 1235237 . T . . . . GT 0/0 0|0 ./. +X 10 rsTest AC A,ATG 10 PASS . GT 0 0/1 0|2 diff -r 000000000000 -r bbf46057ef48 tool_dependencies.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_dependencies.xml Mon Nov 09 12:29:05 2015 -0500 @@ -0,0 +1,6 @@ + + + + + + diff -r 000000000000 -r bbf46057ef48 vcfallelicprimitives.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/vcfallelicprimitives.xml Mon Nov 09 12:29:05 2015 -0500 @@ -0,0 +1,62 @@ + + + Split alleleic primitives (gaps or mismatches) into multiple VCF lines + + macros.xml + + + + + cat "${input}" | vcfallelicprimitives + ${m_option} + -t "${t_option}" + -L "${max_length}" + $keep_info + $keep_geno > "${out_file1}" + + + + + + + + + + + + + + + + + + + + +If multiple alleleic primitives (gaps or mismatches) are specified in a single VCF record, this tools splits the record into multiple lines, but drops all INFO fields. +"Pure" MNPs are split into multiple SNPs unless the -m flag is provided. +Genotypes are phased where complex alleles have been decomposed, provided genotypes in the input. + +The options are:: + + -m, --use-mnps Retain MNPs as separate events (default: false). + -t, --tag-parsed FLAG Tag records which are split apart of a complex allele with this flag. + -L, --max-length LEN Do not manipulate records in which either the ALT or + REF is longer than LEN (default: 200). + -k, --keep-info Maintain site and allele-level annotations when decomposing. + Note that in many cases, such as multisample VCFs, these won't + be valid post-decomposition. For biallelic loci in single-sample + VCFs, they should be usable with caution. + -g, --keep-geno Maintain genotype-level annotations when decomposing. Similar + caution should be used for this as for --keep-info. + +---- + +Vcfallelicprimitives @IS_PART_OF_VCFLIB@ + + +