Mercurial > repos > devteam > table_annovar
diff table_annovar.xml @ 0:525e6995fe44 draft default tip
planemo upload for repository Nonehttps://github.com/galaxyproject/tools-devteam/tree/master/tools/table_annovar commit 5a4e0ca9992af3a6e5ed2b533f04bb82ce761e0b
author | devteam |
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date | Mon, 09 Nov 2015 11:58:50 -0500 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/table_annovar.xml Mon Nov 09 11:58:50 2015 -0500 @@ -0,0 +1,126 @@ +<tool id="table_annovar" name="ANNOVAR Annotate VCF" version="0.2"> + <description>with functional information using ANNOVAR</description> + + <requirements> + <requirement type="package">annovar</requirement> + <requirement type="set_environment">SCRIPT_PATH</requirement> + </requirements> + + <command> + ## Convert VCF to AV input format. + #if str($out_format) == "tabular": + convert2annovar.pl -format vcf4 -includeinfo ${input} > input.avinput ; + #set tab_anno_input = "input.avinput" + #else: + #set tab_anno_input = $input + #end if + + ## Variant annotation; make sure to include entry in indexes table for build database. + + #set protocol = [] + #set operation = [] + + ## Add gene annotations. + #if $gene_anns: + #silent protocol.append( str( $gene_anns ) ) + #silent operation.append( ','.join( ['g' for t in range( str($gene_anns).count(',') + 1 )] ) ) + #end if + + ## Add regions. + #if $regions: + #silent protocol.append( str( $regions ) ) + #silent operation.append( ','.join( ['r' for t in range( str($regions).count(',') + 1 )] ) ) + #end if + + ## Add filters. + #if $filters: + #silent protocol.append( str( $filters ) ) + #silent operation.append( ','.join( ['f' for t in range( str($filters).count(',') + 1 )] ) ) + #end if + + #set protocol = ','.join( $protocol ) + #set operation = ','.join( $operation ) + + ## Annotate variants. + table_annovar.pl ${tab_anno_input} ${__get_data_table_entry__('annovar_indexes', 'dbkey', $input.dbkey, 'path')} -protocol ${protocol} -operation ${operation} -nastring '.' -buildver ${input.dbkey} --outfile output + + ## Add option to consume/produce VCF. + #if str($out_format) == "vcf": + --vcfinput + #end if + + ## Post-processing: process annotated table to remove "NA" strings from numerical columns if + ## tabular. Copy to output. + #if str($out_format) == "tabular": + ; cat output.${input.dbkey}_multianno.txt | python \${SCRIPT_PATH}/replace_NA.py > ${output} + #else: + ; cp output.${input.dbkey}_multianno.vcf ${output} + #end if + </command> + + <inputs> + <param name="input" type="data" format="vcf" metadata_name="dbkey" label="Variants" help=""> + <validator type="unspecified_build" /> + </param> + + <param name="gene_anns" type="select" multiple="True" optional="True" label="Gene Annotations" help="" > + <options from_data_table="annovar_indexes"> + <filter type="data_meta" key="dbkey" ref="input" column="1"/> + <filter type="static_value" name="type" value="gene_ann" column="2"/> + </options> + </param> + + <param name="regions" type="select" multiple="True" optional="True" label="Annotation Regions" help="" > + <options from_data_table="annovar_indexes"> + <filter type="data_meta" key="dbkey" ref="input" column="1"/> + <filter type="static_value" name="type" value="region" column="2"/> + </options> + </param> + + <param name="filters" type="select" multiple="True" label="Annotation Databases" help="" > + <options from_data_table="annovar_indexes"> + <filter type="data_meta" key="dbkey" ref="input" column="1"/> + <filter type="static_value" name="type" value="filter" column="2"/> + </options> + </param> + + <param name="out_format" type="select" label="Output data type"> + <option value="vcf">VCF</option> + <option value="tabular">Tabular</option> + </param> + + </inputs> + + <stdio> + <regex match=".*" source="both" level="log" description="tool progress"/> + </stdio> + + <outputs> + <data name="output" format="tabular"> + <change_format> + <when input="out_format" value="vcf" format="vcf"/> + </change_format> + </data> + </outputs> + + <tests> + </tests> + + <help> +**What it does** + +This tool will annotate variants using specified gene annotations, regions, and filtering databases. Input is a VCF dataset, and output is a table of annotations for each variant in the +VCF dataset or a VCF dataset with the annotations in INFO fields. + +**ANNOVAR Website and Documentation** + +Website: http://www.openbioinformatics.org/annovar/ + +Paper: http://nar.oxfordjournals.org/content/38/16/e164 + +**Important Usage Note** + +ANNOVAR is open-source and free for non-profit use. If you use it for commercial purposes, please contact BIOBASE (info@biobase-international.com) directly for license related issues. Also see http://www.openbioinformatics.org/annovar/annovar_faq.html#license + + </help> +</tool>