# HG changeset patch # User devteam # Date 1580991071 0 # Node ID 37df866ccf1af18848cff332abcf6a12f8dc6dd0 # Parent efd77ef84903e4e3a839e722300089656e894a1d "planemo upload for repository https://github.com/galaxyproject/tools-devteam/tree/master/tools/sam_pileup commit 8301d37348be25a038b3c63b049b1178d05f5003" diff -r efd77ef84903 -r 37df866ccf1a sam_pileup.py --- a/sam_pileup.py Tue Oct 13 12:30:34 2015 -0400 +++ /dev/null Thu Jan 01 00:00:00 1970 +0000 @@ -1,146 +0,0 @@ -#!/usr/bin/env python - -""" -Creates a pileup file from a bam file and a reference. - -usage: %prog [options] - -p, --input1=p: bam file - -o, --output1=o: Output pileup - -R, --ref=R: Reference file type - -n, --ownFile=n: User-supplied fasta reference file - -b, --bamIndex=b: BAM index file - -g, --index=g: Path of the indexed reference genome - -s, --lastCol=s: Print the mapping quality as the last column - -i, --indels=i: Only output lines containing indels - -M, --mapCap=M: Cap mapping quality - -c, --consensus=c: Call the consensus sequence using MAQ consensu model - -T, --theta=T: Theta paramter (error dependency coefficient) - -N, --hapNum=N: Number of haplotypes in sample - -r, --fraction=r: Expected fraction of differences between a pair of haplotypes - -I, --phredProb=I: Phred probability of an indel in sequencing/prep - -""" - -import os, shutil, subprocess, sys, tempfile -from galaxy import eggs -import pkg_resources; pkg_resources.require( "bx-python" ) -from bx.cookbook import doc_optparse - -def stop_err( msg ): - sys.stderr.write( '%s\n' % msg ) - sys.exit() - -def __main__(): - #Parse Command Line - options, args = doc_optparse.parse( __doc__ ) - # output version # of tool - try: - tmp = tempfile.NamedTemporaryFile().name - tmp_stdout = open( tmp, 'wb' ) - proc = subprocess.Popen( args='samtools 2>&1', shell=True, stdout=tmp_stdout ) - tmp_stdout.close() - returncode = proc.wait() - stdout = None - for line in open( tmp_stdout.name, 'rb' ): - if line.lower().find( 'version' ) >= 0: - stdout = line.strip() - break - if stdout: - sys.stdout.write( 'Samtools %s\n' % stdout ) - else: - raise Exception - except: - sys.stdout.write( 'Could not determine Samtools version\n' ) - #prepare file names - tmpDir = tempfile.mkdtemp() - tmpf0 = tempfile.NamedTemporaryFile( dir=tmpDir ) - tmpf0_name = tmpf0.name - tmpf0.close() - tmpf0bam_name = '%s.bam' % tmpf0_name - tmpf0bambai_name = '%s.bam.bai' % tmpf0_name - tmpf1 = tempfile.NamedTemporaryFile( dir=tmpDir ) - tmpf1_name = tmpf1.name - tmpf1.close() - #link bam and bam index to working directory (can't move because need to leave original) - os.symlink( options.input1, tmpf0bam_name ) - os.symlink( options.bamIndex, tmpf0bambai_name ) - #get parameters for pileup command - if options.lastCol == 'yes': - lastCol = '-s' - else: - lastCol = '' - if options.indels == 'yes': - indels = '-i' - else: - indels = '' - opts = '%s %s -M %s' % ( lastCol, indels, options.mapCap ) - if options.consensus == 'yes': - opts += ' -c -T %s -N %s -r %s -I %s' % ( options.theta, options.hapNum, options.fraction, options.phredProb ) - #prepare basic pileup command - cmd = 'samtools pileup %s -f %s %s > %s' - try: - # have to nest try-except in try-finally to handle 2.4 - try: - #index reference if necessary and prepare pileup command - if options.ref == 'indexed': - if not os.path.exists( "%s.fai" % options.index ): - raise Exception, "Indexed genome %s not present, request it by reporting this error." % options.index - cmd = cmd % ( opts, options.index, tmpf0bam_name, options.output1 ) - elif options.ref == 'history': - os.symlink( options.ownFile, tmpf1_name ) - cmdIndex = 'samtools faidx %s' % ( tmpf1_name ) - tmp = tempfile.NamedTemporaryFile( dir=tmpDir ).name - tmp_stderr = open( tmp, 'wb' ) - proc = subprocess.Popen( args=cmdIndex, shell=True, cwd=tmpDir, stderr=tmp_stderr.fileno() ) - returncode = proc.wait() - tmp_stderr.close() - # get stderr, allowing for case where it's very large - tmp_stderr = open( tmp, 'rb' ) - stderr = '' - buffsize = 1048576 - try: - while True: - stderr += tmp_stderr.read( buffsize ) - if not stderr or len( stderr ) % buffsize != 0: - break - except OverflowError: - pass - tmp_stderr.close() - #did index succeed? - if returncode != 0: - raise Exception, 'Error creating index file\n' + stderr - cmd = cmd % ( opts, tmpf1_name, tmpf0bam_name, options.output1 ) - #perform pileup command - tmp = tempfile.NamedTemporaryFile( dir=tmpDir ).name - tmp_stderr = open( tmp, 'wb' ) - proc = subprocess.Popen( args=cmd, shell=True, cwd=tmpDir, stderr=tmp_stderr.fileno() ) - returncode = proc.wait() - tmp_stderr.close() - #did it succeed? - # get stderr, allowing for case where it's very large - tmp_stderr = open( tmp, 'rb' ) - stderr = '' - buffsize = 1048576 - try: - while True: - stderr += tmp_stderr.read( buffsize ) - if not stderr or len( stderr ) % buffsize != 0: - break - except OverflowError: - pass - tmp_stderr.close() - if returncode != 0: - raise Exception, stderr - except Exception, e: - stop_err( 'Error running Samtools pileup tool\n' + str( e ) ) - finally: - #clean up temp files - if os.path.exists( tmpDir ): - shutil.rmtree( tmpDir ) - # check that there are results in the output file - if os.path.getsize( options.output1 ) > 0: - sys.stdout.write( 'Converted BAM to pileup' ) - else: - stop_err( 'The output file is empty. Your input file may have had no matches, or there may be an error with your input file or settings.' ) - -if __name__ == "__main__" : __main__() diff -r efd77ef84903 -r 37df866ccf1a sam_pileup.xml --- a/sam_pileup.xml Tue Oct 13 12:30:34 2015 -0400 +++ b/sam_pileup.xml Thu Feb 06 12:11:11 2020 +0000 @@ -1,124 +1,126 @@ - - from BAM dataset - - samtools - - - sam_pileup.py - --input1=$input1 - --output=$output1 - --ref=$refOrHistory.reference - #if $refOrHistory.reference == "history": - --ownFile=$refOrHistory.ownFile - #else: - --index=${refOrHistory.index.fields.path} - #end if - --bamIndex=${input1.metadata.bam_index} - --lastCol=$lastCol - --indels=$indels - --mapCap=$mapCap - --consensus=$c.consensus - #if $c.consensus == "yes": - --theta=$c.theta - --hapNum=$c.hapNum - --fraction=$c.fraction - --phredProb=$c.phredProb - #else: - --theta="None" - --hapNum="None" - --fraction="None" - --phredProb="None" - #end if - - - - - - - - - - - - - - - - - - + + from BAM dataset + + samtools + + '$output1' + ]]> + + + + + + + + + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ]]> + + 10.1093/bioinformatics/btp352 + - - diff -r efd77ef84903 -r 37df866ccf1a tool_dependencies.xml --- a/tool_dependencies.xml Tue Oct 13 12:30:34 2015 -0400 +++ /dev/null Thu Jan 01 00:00:00 1970 +0000 @@ -1,6 +0,0 @@ - - - - - -