# HG changeset patch # User deepakjadmin # Date 1452090996 18000 # Node ID 28319c6588ffae566c44e0b9d3eb71afd9c233fd # Parent 5de5c4d3c7401ef2ebecdda8b80afb369ba34126 Uploaded diff -r 5de5c4d3c740 -r 28319c6588ff addact.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/addact.xml Wed Jan 06 09:36:36 2016 -0500 @@ -0,0 +1,29 @@ + +"Merge data files of Active and Inactive compounds " +tool2/addact.pl $Input1 $Activity1 $Input2 $Activity2 $Merged_file + + + + + + + + + + + + + + + + + +Provide descriptor files of active/positive and inactive/negative molecules and assign them properly. + + diff -r 5de5c4d3c740 -r 28319c6588ff padelnew.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/padelnew.xml Wed Jan 06 09:36:36 2016 -0500 @@ -0,0 +1,83 @@ + + + + padel + + + + +"PaDEL Descriptor Calculation Tool" + +#if '.smi' in $input.name +/bin/mkdir $input.extra_files_path; +ln -s $input $input.extra_files_path/molecule.smi; +/usr/bin/java -jar $PACKAGE_BASE/bin/PaDEL-Descriptor.jar -dir $input.extra_files_path/molecule.smi -2d $detectaromaticity $removesalt $standardizenitro $convert3d $retain3d $coordinate $fingerprint $retainorder -file $descriptor -log > $log ; +/bin/rm -rf $input.extra_files_path; +#else +/usr/bin/java -jar $PACKAGE_BASE/bin/PaDEL-Descriptor.jar -dir $input -2d $detectaromaticity $removesalt $standardizenitro $convert3d $retain3d $coordinate $fingerprint $retainorder -file $descriptor -log >$log +#end if + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Input may be any sdf,smile or mol2 file and output file will be in CSV format. + + + diff -r 5de5c4d3c740 -r 28319c6588ff removeduplecate.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/removeduplecate.xml Wed Jan 06 09:36:36 2016 -0500 @@ -0,0 +1,13 @@ + +"Removes Repeated Entry From File" +tool3/removeduplecate.R $Input1 $Non_redudant_mega_file + + + + + + + +run command with Descriptor file and in csv format only .output file will be in CSV format. + + diff -r 5de5c4d3c740 -r 28319c6588ff tool_dependencies.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_dependencies.xml Wed Jan 06 09:36:36 2016 -0500 @@ -0,0 +1,21 @@ + + + + + + + http://www.yapcwsoft.com/dd/padeldescriptor/PaDEL-Descriptor.zip + + . + $INSTALL_DIR/bin/ + + + + + $INSTALL_DIR/bin + + + + + +