Mercurial > repos > davidvanzessen > mutation_analysis
comparison mutation_analysis.py @ 104:603a10976e9c draft
Uploaded
| author | davidvanzessen |
|---|---|
| date | Wed, 22 Jun 2016 10:07:28 -0400 |
| parents | 5ffbf40cdd4b |
| children | 01c9993865af |
comparison
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| 103:e21cbe15381f | 104:603a10976e9c |
|---|---|
| 79 IDlist += [ID] | 79 IDlist += [ID] |
| 80 | 80 |
| 81 AALength = (int(max(mutationList, key=lambda i: int(i[4]) if i[4] else 0)[4]) + 1) # [4] is the position of the AA mutation, None if silent | 81 AALength = (int(max(mutationList, key=lambda i: int(i[4]) if i[4] else 0)[4]) + 1) # [4] is the position of the AA mutation, None if silent |
| 82 | 82 |
| 83 AA_mutation = [0] * AALength | 83 AA_mutation = [0] * AALength |
| 84 AA_mutation_dic = {"ca": AA_mutation[:], "cg": AA_mutation[:], "cm": AA_mutation[:], "un": AA_mutation[:]} | |
| 84 AA_mutation_empty = AA_mutation[:] | 85 AA_mutation_empty = AA_mutation[:] |
| 85 | 86 |
| 86 aa_mutations_by_id_file = outfile[:outfile.rindex("/")] + "/aa_id_mutations.txt" | 87 aa_mutations_by_id_file = outfile[:outfile.rindex("/")] + "/aa_id_mutations.txt" |
| 87 with open(aa_mutations_by_id_file, 'w') as o: | 88 with open(aa_mutations_by_id_file, 'w') as o: |
| 88 for ID in mutationListByID.keys(): | 89 for ID in mutationListByID.keys(): |
| 89 AA_mutation_for_ID = AA_mutation_empty[:] | 90 AA_mutation_for_ID = AA_mutation_empty[:] |
| 90 for mutation in mutationListByID[ID]: | 91 for mutation in mutationListByID[ID]: |
| 91 if mutation[4]: | 92 if mutation[4]: |
| 92 AA_mutation[int(mutation[4])] += 1 | 93 AA_mutation_position = int(mutation[4]) |
| 93 AA_mutation_for_ID[int(mutation[4])] += 1 | 94 AA_mutation[AA_mutation_position] += 1 |
| 95 AA_mutation_for_ID[AA_mutation_position] += 1 | |
| 96 clss = genedic[ID][:2] | |
| 97 AA_mutation_dic[clss][AA_mutation_position] += 1 | |
| 94 o.write(ID + "\t" + "\t".join([str(x) for x in AA_mutation_for_ID[1:]]) + "\n") | 98 o.write(ID + "\t" + "\t".join([str(x) for x in AA_mutation_for_ID[1:]]) + "\n") |
| 95 | 99 |
| 96 | 100 |
| 97 | 101 |
| 98 #absent AA stuff | 102 #absent AA stuff |
| 145 | 149 |
| 146 aa_mutations_file = outfile[:outfile.rindex("/")] + "/aa_mutations.txt" | 150 aa_mutations_file = outfile[:outfile.rindex("/")] + "/aa_mutations.txt" |
| 147 with open(aa_mutations_file, 'w') as o: | 151 with open(aa_mutations_file, 'w') as o: |
| 148 o.write("row.name\t" + "\t".join([str(x) for x in range(1, AALength-1)]) + "\n") | 152 o.write("row.name\t" + "\t".join([str(x) for x in range(1, AALength-1)]) + "\n") |
| 149 o.write("mutations.at.position\t" + "\t".join([str(x) for x in AA_mutation[1:]]) + "\n") | 153 o.write("mutations.at.position\t" + "\t".join([str(x) for x in AA_mutation[1:]]) + "\n") |
| 154 o.write("AA.at.position\t" + "\t".join([str(x) for x in absentAA]) + "\n") | |
| 155 | |
| 156 | |
| 157 aa_mutations_file_ca = outfile[:outfile.rindex("/")] + "/aa_mutations_ca.txt" | |
| 158 with open(aa_mutations_file_ca, 'w') as o: | |
| 159 o.write("row.name\t" + "\t".join([str(x) for x in range(1, AALength-1)]) + "\n") | |
| 160 o.write("mutations.at.position\t" + "\t".join([str(x) for x in AA_mutation_dic["ca"][1:]]) + "\n") | |
| 161 o.write("AA.at.position\t" + "\t".join([str(x) for x in absentAA]) + "\n") | |
| 162 | |
| 163 | |
| 164 aa_mutations_file_cg = outfile[:outfile.rindex("/")] + "/aa_mutations_cg.txt" | |
| 165 with open(aa_mutations_file_cg, 'w') as o: | |
| 166 o.write("row.name\t" + "\t".join([str(x) for x in range(1, AALength-1)]) + "\n") | |
| 167 o.write("mutations.at.position\t" + "\t".join([str(x) for x in AA_mutation_dic["cg"][1:]]) + "\n") | |
| 168 o.write("AA.at.position\t" + "\t".join([str(x) for x in absentAA]) + "\n") | |
| 169 | |
| 170 | |
| 171 aa_mutations_file_cm = outfile[:outfile.rindex("/")] + "/aa_mutations_cm.txt" | |
| 172 with open(aa_mutations_file_cm, 'w') as o: | |
| 173 o.write("row.name\t" + "\t".join([str(x) for x in range(1, AALength-1)]) + "\n") | |
| 174 o.write("mutations.at.position\t" + "\t".join([str(x) for x in AA_mutation_dic["cg"][1:]]) + "\n") | |
| 150 o.write("AA.at.position\t" + "\t".join([str(x) for x in absentAA]) + "\n") | 175 o.write("AA.at.position\t" + "\t".join([str(x) for x in absentAA]) + "\n") |
| 151 | 176 |
| 152 if linecount == 0: | 177 if linecount == 0: |
| 153 print "No data, exiting" | 178 print "No data, exiting" |
| 154 with open(outfile, 'w') as o: | 179 with open(outfile, 'w') as o: |
