# HG changeset patch # User boris # Date 1372135846 14400 # Node ID 479f860eb8a9c5d639f2e4cfee676f9e7ef254f0 # Parent 57c5ea9c3c5c89c7c7cc86c279527ce638e114f6 updated tool xml description diff -r 57c5ea9c3c5c -r 479f860eb8a9 hetbox.xml --- a/hetbox.xml Fri Jun 21 16:05:46 2013 -0400 +++ b/hetbox.xml Tue Jun 25 00:50:46 2013 -0400 @@ -1,5 +1,5 @@ - - from allele counts + + R rpy2 @@ -8,12 +8,12 @@ hetbox.py $input $outplot $outreport - - + + - - + + report is True @@ -28,19 +28,47 @@ **What it does** -Given a table with sample ids and minor alelles frequencies, generates boxplot per sample and +The MAF Boxplot tool takes a table listing heteroplasmic sites per sample and their corresponding minor allele frequency. +It generates a boxplot of the minor allele frequencies per sample by default. +Optionally, it can generate a report including the total number of heteroplasmic sites and the median and the median absolute deviation (MAD) of the minor allele frequencies per sample. + +----- + +.. class:: warningmark + +**Note** + +Please, follow the format described below for the input file: + +----- .. class:: infomark -**Boxplot** +**Formats** -The graphic shows the distribution of the minor allele frequencies as a boxplot per sample. At the bottom of each plot, a count (N) is given of the number of minor alleles in the plot. +**Count alleles tool output format** +Columns:: -**Report** + 1. sample id + 2. chromosome + 3. position + 4 counts for A's + 5. counts for C's + 6. counts for G's + 7. counts for T's + 8. Coverage + 9. Number of alleles passing frequency threshold + 10. Major allele + 11. Minor allele + 12. Minor allele frequency in position -The graphic shows the distribution of the minor allele frequencies as a boxplot per sample. At the bottom of each plot, a count (N) is given of the number of minor alleles in the plot. +----- +**Citation** + +If you use this tool, please cite Dickins B, Rebolledo-Jaramillo B, et al. *In preparation.* +(boris-at-bx.psu.edu)