# HG changeset patch
# User bgruening
# Date 1633687032 0
# Node ID cc01cbc4e7f70aab52b930cdb17a52d5e94cdfaf
# Parent  313e04fe07cdc1d46df02f2d447767702e9099be
"planemo upload for repository https://github.com/bgruening/galaxytools/tree/master/tools/trim_galore commit 276a0ec327f5369c16563696047f0d31577c353f"

diff -r 313e04fe07cd -r cc01cbc4e7f7 macros.xml
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/macros.xml	Fri Oct 08 09:57:12 2021 +0000
@@ -0,0 +1,66 @@
+<macros>
+    <token name="@TOOL_VERSION@">0.6.7</token>
+    <token name="@VERSION_SUFFIX@">0</token>
+    <xml name="requirements">
+        <requirements>
+            <requirement type="package" version="@TOOL_VERSION@">trim-galore</requirement>
+        </requirements>
+    </xml>
+    <xml name="xrefs">
+        <xrefs>
+            <xref type="bio.tools">trim_galore</xref>
+        </xrefs>
+    </xml>
+    <xml name="adapter_trimming">
+        <conditional name="trimming">
+            <param name="trimming_select" type="select" label="Adapter sequence to be trimmed">
+                <option value="">Automatic detection</option>
+                <option value="--illumina">Illumina universal</option>
+                <option value="--nextera">Nextera transposase</option>
+                <option value="--small_rna">Illumina small RNA adapters</option>
+                <option value="user">User defined adapter sequence</option>
+            </param>
+            <when value=""/>
+            <when value="--illumina"/>
+            <when value="--nextera"/>
+            <when value="--small_rna"/>
+            <when value="user">
+                <param name="adapter" type="text" value="AGATCGGAAGAGC" label="Adapter sequence to be trimmed off">
+                    <validator type="regex" message="Adapter sequence must contain DNA characters only (A,C,T,G or N)">^[ACTGNactgn]*$</validator>
+                </param>
+                <yield/>
+            </when>
+        </conditional>
+    </xml>
+    <xml name="paired_adapter_trimming">
+        <expand macro="adapter_trimming">
+            <param name="adapter2" type="text" optional="True" value="" label="Adapter sequence to be trimmed off read 2">
+                <validator type="regex" message="Adapter sequence must contain DNA characters only (A,C,T,G or N)">^[ACTGNactgn]*$</validator>
+            </param>
+        </expand>
+        <param name="trim1" type="boolean" truevalue="--trim1" falsevalue="" checked="False" label="Trims 1 bp off every read from its 3' end." help="" />
+        <param name="three_prime_clip_R1" type="integer" value="" optional="True" label="Remove N bp from the 3' end of read 1">
+            <help>Instructs Trim Galore! to remove N bp from the 3' end of read 1 after adapter/quality trimming has been performed.
+                This may remove some unwanted bias from the 3' end that is not directly related to adapter sequence or basecall quality.
+                (--three_prime_clip_R1)</help>
+        </param>
+        <param name="three_prime_clip_R2" type="integer" value="" optional="True" label="Remove N bp from the 3' end of read 2">
+            <help>Instructs Trim Galore! to remove N bp from the 3' end of read 2 after
+                adapter/quality trimming has been performed. This may remove some unwanted bias from
+                the 3' end that is not directly related to adapter sequence or basecall quality.</help>
+        </param>
+    </xml>
+    <xml name="citations">
+        <citations>
+            <citation type="bibtex">
+                @misc{githubTrim_Galore,
+                author = {Krueger, Felix},
+                year = {2021},
+                title = {Trim Galore},
+                publisher = {GitHub},
+                journal = {GitHub repository},
+                url = {https://https://github.com/FelixKrueger/TrimGalore.com/fenderglass/Flye}}
+            </citation>        
+        </citations>
+    </xml>
+</macros>
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/mec_reads_pair1.fastqsanger
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/mec_reads_pair1.fastqsanger	Fri Oct 08 09:57:12 2021 +0000
@@ -0,0 +1,396 @@
+@M01368:8:000000000-A3GHV:1:1101:6911:8255/1:R1:ATCTGGTT:R2:TCGCCTTA:F1:CCTA:F2:CCGC
+TTCAGGGCCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATT
++
+GGGGGGGGGGHHHHGHGHHHHHHHHHGGGGGGHHHHGHHHHHHHHHHGHHHHHHGGHGGHHHGHHHHFHHGHHHHHHHHHGHEHEFFGHHEGGCEFGGFHHHBGHHGHHHHGHFHHHGHGHGHGGCDFDDACGGGGGGGAAFFFFFFFFFBAFFFFFB;FFFFFFADDFFFFFFFFFFEFFFFFFFFFFBFFFFFFFFFFFFFFEFFFFFFFFBFEFFFFEFE;DFFFDFBFF/9BFB
+@M01368:8:000000000-A3GHV:1:1101:14518:9998/1:R1:GTTATTAT:R2:CATCACGA:F1:TATG:F2:TGGA
+CCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGAT
++
+GGGGGGGGGHGGHHHHGHHHHHHHGCGHHHHHHHHHHHHHHHGGGGGHHHHHHHHHGHHGFHFE5BGEEHFGGGHHHHHHHHFBHHGGGGFHGHHFGHHHHGHHHHHHGEGGGGFHFHGEGHHGGCDGDGHGGGDGGHGGCGGGHGHHH/ACDG?.1FGCDCCGCA.CC@CDCHFHGFFGGGEBFGAB//CEFBFGG.:;D;;A0AFFFFFB..:@ABFF//;BFFFFFBF/9D:A//
+@M01368:8:000000000-A3GHV:1:1101:18422:19051/1:R1:GTATCCGA:R2:CTACAAGC:F1:CATC:F2:ATTA
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHFHHHHGGGGHHHHHHHHHGHHHHHHHHHHHHGGHGGHHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHGCGGGHHHHHHHHHHHHHHHHHHHHHHGFDHGFHCFGGGGFGGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF;FFFFFFFFFFFFFFFFFFFFFFFFFFFFEFBFFFFFFFFFF:FFF.
+@M01368:8:000000000-A3GHV:1:1101:25545:21098/1:R1:ATTAATTA:R2:GCCCATAA:F1:ACAC:F2:CACT
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATAAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGGCTTATTTAAGGGGAACGGGTGGGG
++
+GGFEBDGEGHEGHGEGHCEGGHHCHGHHFFHHGFGAGE53FF2FAFFGDE5FFFE5GFBFGAEE1GHHHGHHHEHE3FGHF@GEGEGGHHGG3FAGFFDE?EEE3GFEGFGFGGCG?GHHHFHGGGC@DHFFHD/A<C@EGFDCGGGHFHHHEGFGHBFHG0:CEHFCHGGED.;0CEF.F99B0CFFEEFGGG0FBFBBF0F/FFBDE?/9//9B.FFBFFFFFFBF..A..;@B--
+@M01368:8:000000000-A3GHV:1:1101:5446:12248/1:R1:AATTAACA:R2:ATCCGACA:F1:CACT:F2:TCTG
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTAT
++
+GGGGGGGFGHHHHHGGGGHHHHHHHHHHHHHHHHGBGHGGHGGHHHHHHHHHHGHGHGGGGGHHHHHHHHGHHHHHHHHHGGGGGHHHHFFGHHHGGGGGGHHHGFGGHHGGGGHHHHHHGGGGGGHGHHGGGGGGGHGGGGGGHHHHHHHHHHHHHFHGGGHHHHGGGGGG:FE;EGEGGGGG/;?FGGGGGGGFFFFGGFFFFFFFFFBFFFFFFFFFFBFFFFFFEFFFFFEFFF
+@M01368:8:000000000-A3GHV:1:1101:5861:6452/1:R1:ATTATGTC:R2:TTATCCGA:F1:CTAC:F2:CATC
+AGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTT
++
+GGGGGGGGGHHHHHHHHHHHGHHHHGHHHHHHHHHHHGGGGHHHHHHHHFHHHHHHGGHGHGGHGGHHHHHHHGGHFHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHHEGGHHGGGGGGHHHGGGGHGGGGGHHHHHHGGGDCGHHHHGGGGGGGHEFGGGGHGHHHGHGGGFGGGGGGGEGGGGGGG?E0CEFGGGGGFEE9EEFFFFFBFFFFFFFBFFBD.AFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1102:10403:6021/1:R1:CGCTCCGG:R2:GGATGAGG:F1:GCCC:F2:CAGG
+TAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTG
++
+FGGGGGFGGHA?EAEFBEAGHFABFGG5FDF5DB1EEGAFDFB53FF5FH@G5FFEHGHEFHFFHBE333GF43GCGGGGE@0?BFGGB0B?FHGFDGGHHHBFFDEGGHGFFFDFE@<1>@FFFGHHHHFHEFGDABFFGG/@DCE<CG1<GF0/DD000=<DHGBDFDCECE/:AC?-;-;9B/ABBB-AD9BFB99AB?BDFBAD-.9..@;=;;..9..9/9;BEF;A:9/BFF
+@M01368:8:000000000-A3GHV:1:1102:10677:23253/1:R1:CCTTAAAT:R2:AATTAACA:F1:AAGA:F2:CACT
+ATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTCTGTCTCTTATACACA
++
+GGGGGGCGGGHHHHHGHHHHHHHHHGHHHHHHHHHHHGHHHHHGGGGGHGHHHHHHHHHHHHHBGFHHHHGHGHGGHGGGCGGGHHHGGGGGGGHHHGHGGGGGGGGGGGGGGGGGGGGFFFFFFFFFFFFFFDFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBFFFFFFFFFEDBDFFFFFFFEFFFE0F0FBFFFF0FFFFFFFFFFFFFFFFF:
+@M01368:8:000000000-A3GHV:1:1102:13809:1733/1:R1:ATATTGAA:R2:NATAAAAC:F1:CGTA:F2:CTAA
+GTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGAGGGCTATTTAGGTTTTATGCTGTCTCTTATACACATCTCCG
++
+GGGGGGGGGHHHHHHHHHHHGHHGGGGGH3EHHHGHGHHHHHHHHHGGCEGGGHHHGGGFHGGGGGGHHGEAEFHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGCFFGHHFGHHHGHHHHHHCHGFHHHHGGHGGG00EHGHHHGFHHGEHGHFFFHHGGFHHHGGGGGGGGGB;;CFFGGFGFFBFFDFED;E.:A?DFFFFFFFF:FFFFF0BFFBBBFFFFFBFF0BFBF9F.
+@M01368:8:000000000-A3GHV:1:1102:17584:10050/1:R1:ATCAAAGA:R2:GTCATAAA:F1:CAGA:F2:ACCT
+ACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCT
++
+GGGGGGGGGGHHHHHGGHHHGGGGGGHHHGFGDHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGEGGHHHHHHHGHGHHGHHHHGHHHHGGGGFDGHFHGEHHHHHHGFFHHHHHHHHHHHHHHHHHGGHHHHHHHHHHFHHHHHHGGGGGHHHHGGGHHGHHHGGGGGGGGGGGFGFFGGGGGGGCFGGGFGGGGGGGFFFFFFFFFFFFFFFFFFF;.BF9ADF/9;A;DFFF0
+@M01368:8:000000000-A3GHV:1:1102:18842:24844/1:R1:CACTTGGG:R2:CTACAAGC:F1:GGTA:F2:ATTA
+CTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCT
++
+GGGGGGGGGHHGHGGHHHGGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHHFHHHHGGGGGHHHHHHHHHHHHHHHHHHHHGGGHGGHHHHHHGHBFGHHHHHHHHBGHHHHHHGHGGGHFGCGGFHHFHFFHHBHHHHFFHFHHHHGGDHGGBC?;@DFBFFFFFFFFFBFFFFFFFFFFFFFF.B?FB.@;;DFFFFFFFFFFFEE-A./BBBFBFBFFF//BFB/BFF/
+@M01368:8:000000000-A3GHV:1:1102:21788:11027/1:R1:GCCCACAC:R2:AATTAACA:F1:GTTC:F2:CACT
+CCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTCTG
++
+GGGGGGGGGGHGHHHHHHGGHGGHHHHHHHHGHHHHHHHHHHHHHHHHHHGHHHHHFGGGGHHHHHHHHHHHHHHHHHHHHHHGHGHGGFCGGCGGGHHHGGGGGGGGGGGGGGGGGGGGGGGGGFFFFFFFFFFFFFFFFFFFFFDFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEF9EFFFFFFFFFFFBFF0FFBBBBFBFBFFFF0
+@M01368:8:000000000-A3GHV:1:1102:5728:8777/1:R1:ATATTGAA:R2:CACTTGGG:F1:CGTA:F2:AGTA
+GTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATG
++
+G5GGGGGGGHHHGHHHHHHHHHHGGGGGHHHHHHGHHHHHHFGHHHGGGGGFHGHGGGHHHGGGCEGHHGG?F1BGGGGGHHHHHGGGGEGGHHHHGGGGGCGHGGGGCGHHHHHHHHHHHHHHHHGGHHHHGGCEEDFDEGGHHHHHHHCEHHFHHHHGHGFHHHFFGGGFFFGGFGBGFFFFFFFFGFDGGD9EFA.DAFA/;FEFF9FB?/BBF/FFFFBBFFFFF/FFEFFFBB
+@M01368:8:000000000-A3GHV:1:1102:5983:21093/1:R1:GTATCCGA:R2:ATTGAACG:F1:CATC:F2:TAGG
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGHHHHHHGFHHHHHHHHGGHHHGHGHHHGGGGFHHHHHHHHGHHHHHHHHHHHHHGGHGGHHHHHHFHGGHHHHFHGHHEHHHHHHHGHHHHHD@FGGHHHHHFFFHHGGHGH?DHHHHHGHGHEGG/@?ADGFGGFFFFAFFFFFFFFFFFFFFFFFFFFFFFAAFFFFFFDFFFFFFFF;D9BFFFFFFFFFFFFFFFFFEFFFBBFFF0BFFFBBFF0EFFFFFFFA
+@M01368:8:000000000-A3GHV:1:1102:7765:18353/1:R1:CTCCGGGC:R2:ATTATGTC:F1:CCAT:F2:CTAC
+ACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTC
++
+GGGGGGGGGGGGGGHHHHHHDHHHHHHHHHHHGGGGGHHGHGHHHGHHHHHHFHHHHGHHHHHHGHGHHHGHHHHHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHHHHHHGFFHHHHHGHHHHHHHHHHHGHHHHHGCFGGHGHFHHGHGHGHHHHGGFHHHHGGGHGBFGCC=BFFFFFFFF-@DFFFFFFFFFFFFFFFFFFFFFFAFFAEF.::FBFBFFE-A9:BFFFF0
+@M01368:8:000000000-A3GHV:1:1103:10405:17879/1:R1:GTATCCGA:R2:CTACAAGC:F1:CATC:F2:ATTA
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGHHHHHHHHHHHHGHHHGHHHHHHHHHHHGGGGGGHHHHHHHHHHHHHHHHHHHHGGHGGHHHGHHGHHGHHHHHHHHHCGGFHHHHGHHHHHGCFGGHHGHHHHHHGFHHHGHHHHHHHGHGHGFF/CC?ADAFGFFFFFFFFFFFFFFDFFFFFFFFAFFFFFFFFFFFEDFFFFFFFFFFAFFFFFFFFFFFFFFFFFFFFFFBBFBFBFFFFFFFFFFFFFFFFF?
+@M01368:8:000000000-A3GHV:1:1103:13493:8205/1:R1:GTAGCTAA:R2:AACGTAGG:F1:AGTG:F2:TGCG
+ACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATT
++
+GGGGGGGGGGGGGGHFHHHHHHHHHHHHHHHHGHHHHHHHHGHHHIHHHHHHHGGGGFHHHHHHHHHHHHHHHHHHHGHGGHGGHHHHHHHHHGHHHHHHHHHHHHHHHHHGHHHH/FGGGGHHHHHHHGGEHHHHHGHHHHHHGHGHEFEFGGFFFFFFFFFFFFFFFFFFFFFAFDFFFFFAFFFF;;@FFEFFFFFFFFFFE=?AFFFFFFFFFFFFFFFFFFBFBBBFFFFEFF
+@M01368:8:000000000-A3GHV:1:1103:14060:21273/1:R1:GTATCCGA:R2:TAATAGGA:F1:CATC:F2:TGAG
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTACTGTCTCTTATACAC
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHGHHHHGGGGGFHHHHHHHHHHHHHHHGHHHHGGHGGHHHHHHHHHHHHHHHHHH?GGHHHHHHGHHHHHFEGGGHHHHHHHHHHHHHHHGFHHHFHGHGHGFGCGG@@BCFGFFFFFFF?FFFFFFFFAFFFAD?@FFEEFFFFFFFFFFFFFFFFFFD9BFF/B/FFF/:/9FB9/BFA//;BFB:FFFBB/BFFFFFBFFFFB/
+@M01368:8:000000000-A3GHV:1:1103:14528:12993/1:R1:GCCCATAA:R2:CTTTAGTA:F1:CACT:F2:AGTA
+GGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGAT
++
+FBCG2EGFFGHHCF5AFHHHFHFHHHGG?CEHBHHDGFHHGHHGHBGHABFFBGHGDGGGFHGHHGGHHHGGG@E1GEHHHGHHFHH3FEDHHHHGFGHGFHHGHFBGA?FGHHHHHGHHFFGHFDFGGHHH2??<ECFHHGHHHHHHHHHGHH<1DFGHGC<.FCB/<=@DCFFFFFEDA=-AAB9B/9B9B-@?.-;A-AFF.=-=BFEFEDEFFFBFEA-A.B//9F9F//;BBB
+@M01368:8:000000000-A3GHV:1:1103:17657:20856/1:R1:AAAGCGAA:R2:CTTTAGTA:F1:CTGT:F2:AGTA
+TCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTAT
++
+GGGGGGGGGHHHHHHHHGHHHHHHHHHHHHHHHHHGHHHHHHGHHHHGGGGGHHHHHHHGHHFHHHHHHHHHHGGGGGHHHHHHHH3BGGHHHHHHHEHHHHHHHGHHHHGEEGGGHHHHHHHHGHHFHGHGHGHGHHCHGGECCDFGB@AFFFFFFFFFFFFFFFFFDAFFFFFFFFFFFFFCAF;AFFFFEFFBBEFFF9FBBFFFFFFFFFFEFFFFFFFFFFFFF/FFFFBFF9
+@M01368:8:000000000-A3GHV:1:1103:23099:3794/1:R1:AAGACAGA:R2:CTTCAGGG:F1:TACT:F2:TCAT
+CGACATAGGGTGTTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCTCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGGATGCCGTCT
++
+GEEGGFGGGGCFGEHCGGGGGGFHFFEDEHFGGDEHHHHHHGGFECGHHHHGFEFGCGHGGFGGGHBGFH3/BF3GGGHHEEEHHG22???BCFFFFFFHHFHFF@FGHH11GHHHHFGFHHHHGGHHHHEFFGFGHFG1DGFGGGGEDCCCAEGGFFHHFHHHHHHCFBBFGBFFF/0;B0B00;B0BBFGBB9BFGEFGGGFFDEEAB;BDDBFBFFFFF@;.9BF..;-./-A=F
+@M01368:8:000000000-A3GHV:1:1103:25465:20010/1:R1:GACATAGG:R2:AACCTAAA:F1:GTGC:F2:TAGC
+CCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATCGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGAAAAAAAAAAAACAACAGAC
++
+GGFEFGGGGHHFEFFHFGGGGGHHHGHFGGGGGHHHGGGGGGGGHGEEEGGHHHGFHEHFHDGHGHEHGF?FGG?GGGGHHGHF4F?2?DDCDHGHHHHHFG2@FGHHHGH?CFGGHFHFHHHHGDDGGHGGGGGHGFH.<AFAGHHHFHGHHFCGFHHHHHGHHHHBGHHGGDGAGF.CEGCFDGGGGGEFFF=B.FFFEFFFFFFADF?/9//BFF.B/;:>---;--..;.../9
+@M01368:8:000000000-A3GHV:1:1103:25519:6301/1:R1:AAATAAGA:R2:CTGTAATA:F1:CATC:F2:TTGA
+CGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGCATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATTTCGT
++
+GG2CF?4FGHGHHCHGGHHBHGFFAGGHHFFHHCGHFEGCECEGHFFFHGHHGFGHFGDAFDGFFEEFEGGBECC/<A@DFBBEGC--:;GHHHGBECG@:9-9.-9C/ABB?B@?.EDAFFFFBAFBFBFBFFFFF//;BBFFFF/;/9BBF/BBFBFFFFFFFFFEFF??BF/.AF./;B/9FFFFFFBFBFFFBFFFBFFFFF/BF/A---9.9A-B?DFFF/B/B?---.//;.
+@M01368:8:000000000-A3GHV:1:1103:6074:6549/1:R1:TAACACTT:R2:TTAGTAAG:F1:GGGG:F2:TATG
+TAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTG
++
+GGGGGGGGG5GFHHHHHGHHHGGGGGHHHGHHHHHHHHHHHHGHHHHHHHHHGGHHHHGHHHHHHGGGGHHHHHHHHHHHHHHGHHHHHHHGGHGGHHHHHHHFGHHGHGHHHHHHHHHHHHHGHHHHHGGGGCHHHHEHGHHHEGHHHFGGHHHHGHGHGHF@CCBDFAFFFFFF-CDFFFFFFFFFFFFFAFFFFFEFF;BFF?FEDFFFFFFFF-A./FFFFFFFFFFFF/BFF/
+@M01368:8:000000000-A3GHV:1:1104:11572:8264/1:R1:GTATCCGA:R2:CATTCAAT:F1:CATC:F2:TGTT
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGGHHGHHGHHHHGFGCHGHHGFFHEHHHHGGGGFGHHHHHHHHHHHHGHHHHHHHGGGGGHHHFFHHGHHHHHHHHHHHEHHHHHHHGHHGHGGEGEGHHHFHHHHGHHHHHHGGHHHHHGHGEGEHCGG-BGDFGFFFFAFFDFFFFEFFCFFDDFFFFFFFEC>;>=EF?AEFFFF;9;=DAFFFFBBFFFBFFF//;BFB.:FBFFBB/BFFFF/BFFE?EFAFEF9
+@M01368:8:000000000-A3GHV:1:1104:11928:24197/1:R1:ACGTAGGT:R2:CCTCGCTC:F1:GCGA:F2:CGGG
+AAATAATGGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATA
++
+GGGGGGGGGHHHGHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHGGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHHHHHGHHHHGHHGHHHHGGHGEEGGGGFHHFHHHGHGEHHHHHHHHHHHHHHHHHGGGGGGFGGGGGGGGFFGGGFGFGAEFEFGFEAFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF@D9
+@M01368:8:000000000-A3GHV:1:1104:12288:20635/1:R1:CACTTGGG:R2:CCTACAAG:F1:GGTA:F2:CATT
+CTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGCCGCAGCATCTGTCTTTGATTCCTGCCT
++
+GGGGFFGD5GGHGFFHGHEGGGGHHHHFFHH5FHGHHHFFHEFHHHHHHGGHHHHHGFHGGHGGGGFHGGGFBHHHFGEGHHHHGHGGGGECEHHFHHGHHFFHFGGGHHHEGHDGHHGHGHFHHHECGCBCHHGFHHFHD1GFHEFHEF?GDCFFEFE0A@;@>BD/9BFBBBBFDFFFF99D=?>DDBFF-AFFEBB9BBEFEFAFFF//-@---;;FBBFBFB///;99999BA9
+@M01368:8:000000000-A3GHV:1:1104:13832:4398/1:R1:CACGATGG:R2:GACAGATA:F1:ATCA:F2:CTGC
+AGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGACAAAAAAAAACACACAACAACCAACACCCAGTAGACTAGTGCGTC
++
+GGGGGGGGGHFHHHHHHHHHGFFHHGGHGGGGGHHHHHHHHHHFHHHHGHHHHHGGHGHGGHGGGGGGGHGFFGGGGDGGHHHHGGGGFGGGGGCFGGEGCDGGGGGGGGGGGGEGF?;BFFFFFFFFFFFFFFFFFF:FFFFFFFFFFFFFFFFFFFFFFF/FFFFFFC.;BFEAFFFFF;@FFBFFFFEF?/FFFFE----:...:...9....9.9...:.9//9////;/9-.-
+@M01368:8:000000000-A3GHV:1:1104:23670:4161/1:R1:ATTCAATT:R2:CGACATCT:F1:GTTA:F2:GGTT
+TATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCC
++
+GGGGGGCGBBGGHHHHHHHHHGHHHHHHHHHHFGGHHHHHHGGFHHHHHHHGGGGGFHHHGHHHHHGHHHHGHHGGGHGGGGHHHHHGHHHHHHEGGGFHHHGFFDGEGHGHFHGHHGEGGGHHBGHGGHGHGGGGG/@FCDFDGFHGGGDFFHFGFFGGGGGHHHHGGGGGGGEGCDG?GGBFFFEE00BFFGABBBAFGGGEGEA.9FFF/./;BFBF./AAF/BFFBBF/F/BFB
+@M01368:8:000000000-A3GHV:1:1104:24927:22253/1:R1:AGCTAAAG:R2:GTAATATT:F1:TGAA:F2:GAAC
+TGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTAT
++
+GGBGFF3EAEEEHFHHFHHHGHHHHDGHHGAEFGHHHGFCHHGHHHBGHHHAEGGHGGFHFBFHHHHHHHHHHFHH1EEHEEHH1FFDEEFCGHBGHHFHEHHHHHH1FCGHHHHEEFGEEGFFCHHH11>GHHF/FG2DGGCGAGGHGGGG@@@BEFFF?@@@FFEFFFFFF?@@FB@BB@FFFE=;==---A9EFBBB/;E;A9B/B/FFFEF/B///;/;9/A/;/9BFFFBFBB
+@M01368:8:000000000-A3GHV:1:1104:4705:7727/1:R1:CTACAAGC:R2:TCCTACTT:F1:ATTA:F2:CAGG
+TTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGG
++
+GGGGGGGGGHHHGHHHGHHHHH6GHHHHFFGGGHHHHHHHHHHHHHHHGGFGGGEGGGHHHHHHHHHHGHE3FGGGGHHHHHFHHHHHHHHHHHHGGGGGHHFHFCGFHHGGGGGGGHHGGGGHHGGGGGGHHHHGGGADCHHHHGDGGGGGGGGC@DGFHEHHHHHHGHHHHGFGDEGFGFFGGGGCFGBEGFGGGFG;C.BFFFFFFFBFBFFFF/F?.AFFF/BFFEFFFFFEFF
+@M01368:8:000000000-A3GHV:1:1104:7756:4776/1:R1:GGCCCATA:R2:CTACAAGC:F1:ACAC:F2:ATTA
+TGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGA
++
+GGGGGGEEFHHHHGHGHHHHHHGGHHHGGGGGGHHGHHHHHGHHGHHHGGFHHHHHHHHGHHHFHHGHHGFGGGGHHHHHHHHGHGHFFHFHHHHHHGGHGFGFHHHGHG?FGHHHHHHHHHHHHHHGHGHHGHGGCDGFFHHHHGHHHHHGHHHGFHGHFHGHGHGH/@CABFFFFFFFACAFF?BBFFBFD-@-.D>FFAF.F.:9---;AADFFFFFBEFFF:9FFFFBBFFFF/
+@M01368:8:000000000-A3GHV:1:1105:11310:21761/1:R1:ATAAATAA:R2:ACTTGGGG:F1:TAGG:F2:GTAG
+TGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTTCACTTT
++
+GGGGGGGGGGHHHHHHHHHHHHGHHHHHGGGGGHHHHHGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHGHHHGHHHGHGHHGHHHHGGHGGG=FFGEHHHHHGHFGGHHGHHHHHFHHHHHHHGGHHHHHHHGHEHHGHHHHHGGGGF9AGE?DEGFFGGGGGGGGGGGGGGFFFF/9FFBFFFFFFFEFFFBFFFFFFFFFFFFEFFF0
+@M01368:8:000000000-A3GHV:1:1105:11578:14676/1:R1:ATTGAACG:R2:GCTCCGGG:F1:TAGG:F2:CCCA
+GCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTC
++
+GGGGGGGGGHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHFGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHHHHHHHHHHHHHGHHHHGGGGGGHGGHGHHHHHHH;CHHHHHHHHHHHHHHHGHGGGGFGGGFGGGGGGGGGGGGFGGGEGGFFFFFFFFFFFFFFFFFFFFFFFFF/FFFFFFFFFFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1105:13575:19255/1:R1:TTAGTAAG:R2:GGTTCCTA:F1:TATG:F2:CTTC
+TCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGTTCCCGTGAGTGGTTAATAGGGTGATAGGCCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+G3A111FFAEGDDBGFDHF00F01BBA00BFGEHFBFFA1FABB0FAE?CFHF1BGFHFB0011F121E//>>1F10>B?EFHGCC/?/BFG/EEGFFEE//BCFDE0?E@@B/?11</?//<@?/F<<<A-<FBGH0.00=G0<<C//./0;;GC....<C.=.00;;BB./:.900////.C000;0090;..//000;C/;;/B/9BA9A9-AEEFF?B---;B99//9/;A//9
+@M01368:8:000000000-A3GHV:1:1105:15502:11453/1:R1:GTCCTACA:R2:GATCACAG:F1:AGCA:F2:GTCT
+TAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCTGTCTCTTATACACATCTC
++
+GGGGGGGGGHHGHHHGHHHHHHHHHFGHHHHHGGGGHGHHHHHGFHHHHGHGGGHHGGHGGHHHHHHHHHHHHHHGGGGGFHGHHHGHHHHHGHHHHGGGGGGHGEGFECHEHGGGGGGHHHGADFHHGGGGHHHHH<ECGGGGHHHHGGGGGGGHGGGGGGHHHGHGHHGEHBFFFGFGEGGGGGEDEGF0C;;BFFFGGGBEFFE/FFFFFFFFFFFFFFEFFFFFFFFBFFFBFF
+@M01368:8:000000000-A3GHV:1:1105:16787:9771/1:R1:GTTATTAT:R2:TCCTACTT:F1:TATG:F2:CAGG
+CCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGAT
++
+GGGGGGGGGHHHHHHHHHHHHHHHHHGHHHHHHHHHHHHHGHHGGGGHIIHHHHHDHHHHHHHGHHHGGHGGHHHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHGGGHHHGGGGGGHHHGGGGHHGGGGGHHHHHGGGGGGHHGHGGGGGGGEEGEGFGHHHGGGGFFGGGGGGGGGGGGGGGEG?G;:EFFFFFFFFF:AEFFFFFFFFBFFFFFFFFFEFF/
+@M01368:8:000000000-A3GHV:1:1105:17564:15723/1:R1:TATGCTCG:R2:ATCCGACA:F1:CCTG:F2:TCTG
+AATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAA
++
+GGGGGGGGGHHHHHGFGHGGHGGHHHHHHHHGHHEHHGGGGGHHHHHHHHHGHHHGHHHHGGGGGHHHHFFGHHHGGGGGGHHHGGGGGHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHFEHHHHHHHHHHGHHGHGGHGGGCGGGGHHH1FGGGFGGFGGGGGGGGGGEFGGGGGGGGGGGGGGGGGFFFFFFFFFFAEFFFFFFFFFFBBFBBFFFFFE1:BFFB0
+@M01368:8:000000000-A3GHV:1:1105:18108:12091/1:R1:TAATAGGA:R2:GTATCCGA:F1:TGAG:F2:CATC
+CAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACAC
++
+GGGGGGGGGHHHHHHHHHHHHHGGGGGGFHHHBFGHHHGGGGGGHHGGGGGHHGFGGHHHHHHGGGGGGHGHFGGGGGGDGEGEFGCHHHHHHHHHHGHHHHGEDHHHGGGCDGGGGFHFHGHHHGHHGHFGHHHFHHGFHHHFHHGGHFHFHHGB0CGHGFHCBGGGGEDEE9ADFEFFFGFBFGFFGGFFFFFGGFGFFFFFFFF/A?FEFFFFFEF-A.B//;BFFEF//BB///
+@M01368:8:000000000-A3GHV:1:1105:18331:16683/1:R1:TCTGGTTC:R2:TTATTATG:F1:CTAC:F2:TCCT
+TCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTA
++
+GGGGGGGGGHHHHHHGHGHHGGGHHGHGGGGFFHHGHHHGHHHHHHH3FGHHGGGHGGHHHHFHHHFHGHHHGHHHHHHHHHHHHGHHHHGGCGGGHHGHHHHHHHHHHHHHFHHGHHGHGHEFGGGGABFFFGBEGGAFFFFFFFFFFFFFDDFF?DFFFFFFFFAEFFFFFFFFFFFFB;9FFFFFEFFFFFFFFFFFF?FFFFFFF/BFFFFFFFB.DABFFFFFFB.//:FB//
+@M01368:8:000000000-A3GHV:1:1105:20577:18421/1:R1:GGGGGTAG:R2:ATGTCCTA:F1:CTAA:F2:CAAG
+GTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCC
++
+EAGGGFGGAA6FHDGGCGFHFFHFHFHHHHHGDDDFFFHGFFHGBEGEGHHHFFFHGEEAEGHHHHHFHHHFHGHFEDGGEGBEAGEFHHFFHHHHHHGGHHHGHHGBGHHFHHFGHHHHG?CG?AFHH1FHHHGHFHHHF?DGHFFHCGAGEFHGCBBBB?BFFF?B-B.9/BFFFFFB=-AD?..@FFFF@@-@@?AFD.FFFBBEEBD9/:FFFFFBB/:FF9BF/BF.BBFF/:
+@M01368:8:000000000-A3GHV:1:1105:21099:2895/1:R1:TAGCTAAA:R2:TTATTATT:F1:GTGA:F2:ATGT
+CTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTT
++
+GGGGGGGGGGGGFHHHHFHGHHHHHHFHHHHFGFHHHHHHGHHHHHHGHHEHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHHHHHHHFHHHHGHGHHHGGHHHHHGGHFFGHGCGGGHGHHGHHHFGHHFHH/FGGGHFGFEGGCFCCD;B@DFFFFFFFFFFFFFFFFFFFFFFFFF;F.BEFADFFFF.AEFFFFFFE;D.;:B00099:09BFBFFBFF.0:000BFFBF0
+@M01368:8:000000000-A3GHV:1:1105:26469:19245/1:R1:TTATGATT:R2:GGGGTAGC:F1:ATGT:F2:TAAA
+CTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCAAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATG
++
+GGGGGFFGGHHHHHHHHHHHHGGHHGHHHGGHHHHHHHHHHHDEGGHGHHHHHGEDHFHGFHGGHHGGHGGEHHHGHHGHHGHHHGGEGGGHGHGHHHHHHGHHHHGHGGGGGHFHGGGGHHGGGGCDGHHHGD<EHHGGGGGHHGHH?EDCCDHHHHDGFFGGGHGGFCGGHHHHFG.CFGGGGGGGGGGGBFGDEG.AFFG;AFFFFEB?/A9BBBFFFFFFF/9FFFFBDEFFFF
+@M01368:8:000000000-A3GHV:1:1105:7169:17145/1:R1:AACCTAAA:R2:CATTCAAT:F1:TAGC:F2:TGTT
+CACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGT
++
+GGGGGGGGGHHHHHHHHHHHBHHHHHHHGGHGGHHHHHHFHHHHHHHHHHHHHHHHHHHHGHHHHHGGGGCHHHHHHHHGHHHHHHHFHHHHHGHGHGHHGGGGGFGGHHGGGGGGGGGGGGEGGFGGGFFFFFFFFFFFFFFFFFFFFFFFFFFFDFFFFFFFFFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFFFFFFFF-9@DDBFFFFFFFFBBFFF0
+@M01368:8:000000000-A3GHV:1:1106:15481:16176/1:R1:CTTTAGTA:R2:AAAGTGAA:F1:AGTA:F2:CTGT
+GTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTT
++
+GGGGGGGGGHHGHGHHHGHHHFGHGFGHFEHGGHGGHHHGHHHHFGHGGFGFFHHFHHHHEGHFHHHHHFGGGGGHGGGHGFHGHGGGGGGHHHGGGGHHGGGGHHHGGHGGGGGGHHHHGGGGGCFHGGGCDGHGHHHFHEHHHHHHHHHEEFHHGG:C:?0<EFGBFGGGGGFE.BFGEFFFGFFGGGGGGFDEF/FFGFFFFFFF;BBFA;.:EFFE:AAFEF.BFFFFF;9FF.
+@M01368:8:000000000-A3GHV:1:1106:17389:18671/1:R1:CCATAACA:R2:GTATGTTC:F1:CTTG:F2:GCCT
+GGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGGCTTTGATTC
++
+GGFEECFGGFFB5GBHH5DFH5GBEEAEFHFHHF3F3GHFHHHEF3GAEHBGFHFFEFFHHHHFFB31FGGEGFHGEHHHHHHHHHHHHHHHHHEEEEGHHHFFF3GF3FGF44BBGEHHHHGG2B/BGGHE</ECDFHHBF1DGBFBFGFH<1GHGDGGFDFE0/<--;-9./BBED;BFBD/BF9BFFFDBFDADD;FFF?->;B=.9.;.BBFFF..;A;/B/;B//;;//BBF/
+@M01368:8:000000000-A3GHV:1:1106:22927:3863/1:R1:GTATCCGA:R2:AAGACAGA:F1:CATC:F2:TACT
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGACTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAA
++
+GGGFGGGFGFHHHFFH4BCBGHHHHGFFF3G5BF3322EEAFHHHHHHAB5GHFHEHFHHH3BEEHFGF5@13FDF3GDGFHHFGHHHGHHHGFGGHHFCG//?/EGHHHG3F4BFFGHHHEDGFHHB/B/?FBF<@-9?BDEFFF?B--?DFFFB9FA>B;A.BFDB?AB.--@;-.FFAEFFFF9AE;DDFFFFB/9BFFFFFFFB:BF/BB/BFF//FFF-=--.99=--.9///
+@M01368:8:000000000-A3GHV:1:1106:23625:4236/1:R1:TAGCTAAA:R2:CACTTTAG:F1:GTGA:F2:TAAG
+CTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTA
++
+GGFGFGGGEFCGGHHHHFGHGHFHGHHHHGGFGGFGHHGHGHHHHGHGFFHHGGGGGHHHHHHHHHBFHHEFHHHHHHGF?FAGHGFHHHGDGFHHGGGHGHFHHHGHHHGHHFHHGFFGFHHHGHHHHFFHHHHH/FGHHHHGHGHG<C???B=@ABBFEF@=-AFFFFFFBFAFFDFFFFA?AFFCFFABEFFFFFFFFF?FFFDFFBFF;FFEFFEFFFFFFFAF///9FF/BB/
+@M01368:8:000000000-A3GHV:1:1106:26031:14826/1:R1:GATCACAG:R2:CTGTAATA:F1:GTCT:F2:TTGA
+TCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATATCGTATGCCGTCTTCTGCTTGA
++
+GGGGGGGGGHHHHHHGHHHHHGGGGGHHHHHHHHGHGHHHHHHHHHHHGHGHFHFGE?CGDGGHHGGGGGGGHHHHGHGGGGGGFGGGHGHGGGGGGGGGGGGGGGGGGDGAFFGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFB/9FFBFFFFFFFFFFFFFD@D=BEFFF;FDDB////B=CF-.;BAFFFFFF;;BFE/BFFFFB:
+@M01368:8:000000000-A3GHV:1:1106:27607:15990/1:R1:GACAGATA:R2:CCCCTTAA:F1:CTGC:F2:ATAA
+ACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGACTTCTGCTTGAAAAAAAAAAACTACAACCCACGGACGCA
++
+GGGGGGGGGGGHHHGGGGGGHHHGGGGGFCEGGHHHGHHGGGEGGHHHAFGGGGGGAFG//EGHHHHCGEHHHHEEHHFHGHFHHGGEF/FGGC?FDFH2DHHFFGGFGHHHHGGHHFGHHGHGHHGFHDHBGBBGHHFHHGGCCDC<=D<DGHHC;CGFCCFBECDG?FGGA-;EB9FBGFFBBF>DFFFE?FFF/--;;9/:BFFFBA///9----;B.//////;...---9---
+@M01368:8:000000000-A3GHV:1:1106:6455:17124/1:R1:GTATCCGA:R2:GCATTAAT:F1:CATC:F2:TAAT
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGHHHGHHGHHHHHHHHHGHHGHHGHHHGHGGGEGHHHHHHHHHHHHHGHHHGHHHGGHGGHHHHHHHHHHHHHHHHHHGHHHHHHHHGHHHHHGGCFEHHHGFHHHHGHHFFH?GGHHHHGHGHGHHCFGGGGGGGFFFFFFFFFFFFFFFFFFFFADFA?.FEFAFFFEFFFFFFFFFFFFDABFBBFFFFFFFFEFFBFFFFFFFFFFF/FFBFFFFFFADE>BFFF9
+@M01368:8:000000000-A3GHV:1:1107:14451:26748/1:R1:GTATGTTC:R2:AGCTAAAG:F1:GCCT:F2:TGAA
+TAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGA
++
+GGGGGGGGGHGHHHHGAGHGGGGGHHHHHHHHGHHHHHGGGGGGFFHHHHHHHHHFHHHHHGGGGCHFHH3FEHHGCGGGDGHHHGFGGHHGGGGHHHHHHG/DGGGHHHHGGGGGCCHGG?CGG1GHHGHHHHBGHHHFHHGHHHHGGADAD00ECEGHEFHHFFAEFFFFFGGFBFBFFFGFFG.;B/99;BCFGGGGEFFFFFFEDA./:ADEB?FBFFFF;FFEBFBFFB./9.
+@M01368:8:000000000-A3GHV:1:1107:18714:24788/1:R1:GTATGTTC:R2:GGCCCATA:F1:GCCT:F2:ACAC
+TAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGA
++
+GGGGGGGGGHHHHHHGGHHGGHGGHHHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHCFGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHGHHHHHHHHHHHGHHHHGGEGEGCCEGGHHHHHHG:CAFFGGGGGGBFEFGGGGHGAFFGGFGGGGGGGEFFFFFFFFFEF/EDDFFFFFFFFFBFFFFFBBFFBBF/
+@M01368:8:000000000-A3GHV:1:1107:21355:8333/1:R1:ATATTGAA:R2:GTATCCGA:F1:CGTA:F2:CATC
+GTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATG
++
+GGGGGGGGGHHHHHHHHFHHHHHGGGGGHHHHHHFHHHGHHHHHHHGGGGGHHHHFFGHGHGGGGGGGHGGEGGGHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHGHHHFHHHHHHHHGHFFHHHHGGHGEGHHGHGFHHFHGHCEFHEGHGHHHGHHHGGGGGGCFFFFBFGGFGGGGFBG?FDGGGEGFFFFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBFF.AA/9
+@M01368:8:000000000-A3GHV:1:1107:22864:15712/1:R1:AATAAGAC:R2:GTAATATT:F1:ATCA:F2:GAAC
+GATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATG
++
+GGGCEGGGGHGHHDGFHHHHHHHHHHHHHCHHGHFGBGDFGE?GHHGHFBHHFHHHHHHHHHGHFGFGHGHHGGC@DCFGHHGGGGGGGHHHHHHGGGGGFGGGGFFGGGGFADGFEFFFFFFFFFFF9;FFFF/BFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFEAECDFFFFFFFFFBFFFFFFFFFFFFFFEFBFBFFF/FFFDF-;-9;E@>-9DFFF/FFBF;-.:;.9A//
+@M01368:8:000000000-A3GHV:1:1107:24817:14233/1:R1:CTTCAGGG:R2:CTTTAGTA:F1:TCAT:F2:AGTA
+AAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACAT
++
+CFGGGGGGGHHHFGCFGGGFFGHHCGHHHGHGHGHBFFHHHEDGGFGFGHHFFFHGGEGHFHHGHFHGFFHHHFGHHHFHACECEHHHBGFHGFHHHFHHF4GFHFHFHEHGGE/EG:A-CFGGFGADGGGGFGGGGDAAAADFA.-AFFECFDAAFFFFEFFFFBFF;D;BFFFB/;BFFFFFFFFFFFFFFBFFBF/;//;BFFFF?FFFFFFEDAFFFFFBF//:BFBACF--9/
+@M01368:8:000000000-A3GHV:1:1107:24830:14440/1:R1:AACTGTAT:R2:CTTTAGTA:F1:CCGA:F2:AGTA
+ATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACC
++
+GGGGGGGGGHGHHGHHGHHHGGHHHHHGHGHHGDHHHHHHAGGGGFHHGHHHHHHGHHHHHHHHHHHEGAFGFHFHHHHGEGHHHHHHHHHHHHHHHHHGGHHHGEFEGGHHGHHHHHGGHGFHH/?GHHHHGFGHGFHCGGBBDAFFFEFFFFFFFFFFFFFF=CDDADDFFFFEF=BFFFEFFFBFFFFEEBF./:FFFFFFFFFFFFFFFFFFFEFFFFFFFFFFF/BFBEFFC-
+@M01368:8:000000000-A3GHV:1:1107:26478:23602/1:R1:GCTAAAGT:R2:ATCAAAGA:F1:GAAC:F2:CAGA
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATCTGTCTCTTATACACCTCTC
++
+EGGGFGGGGGGHHDB1BGFHHHFGFGGG0F00BGBGFGGF1GBGB1BGCGAEE/FGFHGHFHHHHHBFF1B0FGGF//F//FGFGFFF/1@B1DFHHHGGEFEDHFDFAFF0B//</ECCC>1FDD1GFFHHDF?1BD>GF/GCAC0C@?@-;99BBB->@--;-B//99B--9-BF=A--A-:A----9AA9AFBFBBB?E@BBFFFFFFFBFFFFFBFFFBBFFF//B/////-;9
+@M01368:8:000000000-A3GHV:1:1108:11059:23181/1:R1:GTTATTAT:R2:AACTGTAT:F1:TATG:F2:CCGA
+CCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGAT
++
+GGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHHHHHHHHGHHGGGGHIIIHHHHHHHGHHHHGHHHGGHGGHHHHHHHHHHHHHHGGGGGHHGHHHHHHHHHHHHHHHGGGGGHHHHHFGHHHGGGGGGHHHGGGGGHGGGGHHHHHHGGGGGGHGGHEFGGGGGHGGG-ECHHHGGGGGGGGGFGFFGGGGFGGGCF?EFGG0;BFFFFB?9AAFFFFFFBF;BBFFBFFFFE?F/
+@M01368:8:000000000-A3GHV:1:1108:12233:13498/1:R1:TAGGTGCG:R2:GGTTCCTA:F1:ATAA:F2:CTTC
+TAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCCTGTCTCTTATACAC
++
+GGGGGGGGGHHHHGGGGGHHHHHHGHGHBGFHHHHHGGGGGHHGGBFGHHGGGGGGGHHHGGGGHHGGGFHHHHHHGGGGGGHGHHGGGGGGGGGGGGGGHHHHFHHHGHGHHHHHHGHGHHGGFGGGDFFGGHHHGHGH/<GHHFGBGFHFBGHHHGHHGEFHFHFGBF0BFGGGFGGGGGEFFF;A?EEG?CFFFFF0:BEFFFFFBFFFFFF0FFEFF?EFFFF0BFFFFBBB00
+@M01368:8:000000000-A3GHV:1:1108:14328:14751/1:R1:ATAATAGG:R2:GTATCCGA:F1:ATGA:F2:CATC
+GCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACA
++
+GGGGGGGGGHHHHHHHGHGHHHHHGGGGGFHHHFFDGHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHGHGGGGGGGGGGGCFGHHHHHHHHHHHHHHHHHGHHHHGGGDGGFGGFGGHHHHHH>FHHHFHGHGHHGHHHGHHBA<CGFHHHHHHHHHHGFHHGDDEGCEGGGGEEFBFGGGGFGGGB0CFF:FFFFFBBFFFFBFEFA.BFFFEFFFBF/BF/FFEFFBFFF/
+@M01368:8:000000000-A3GHV:1:1108:16350:22621/1:R1:TTAGTAAG:R2:CATCTGGT:F1:TATG:F2:TCCT
+TCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+GGFGGGGGGHHHHHHGBGGGFGGGHFGGGGGHHHHHGGHHHHFHGGGGGGHHGFHHHHHGEFHHFFHHGFCEFHHHGFF?GHHEE@ECFHHEGGGGBFFEGGGHFDHHGFG/BFEHHFCDGGGCDEGGGCGFFFHHHFEGHFHHHHGHHDGHHHGGHDED0CE;CFFFFBFF/;CBFFFGG0/FFF0B0:BB?.;BFF0FGFBFFFFFEFE;ADED.;BE.99FAFFFFFFF/;EFF/
+@M01368:8:000000000-A3GHV:1:1108:21791:23272/1:R1:CTTTAGTA:R2:CATAACAC:F1:AGTA:F2:TTGG
+GTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTA
++
+GGGGGGCGGGHHHHHHHHGHHACGDAGFEEHGGHHGHHHHHHHHHHHGGGGGGHHHHGFHFGHGFDDGFFFGGFGHHFF?FEGHHGGGGGGHHHGFFDHHFGG?HEFGHHGGGDDCGFFC?ECCFGDEFGGGGGGFHHHHHHHEFHFCGHHGEGGGGD.:.A;CECAFFFFBFF/;EFFBFFBFB;;BFFFFBBAA./BFFEBB//BFFFFFFFDFFFEEFEFFFBFBFBBFFFFF./
+@M01368:8:000000000-A3GHV:1:1108:23314:26089/1:R1:ATTGAACG:R2:CATAACAC:F1:TAGG:F2:TTGG
+GCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTG
++
+FBFGGEGGGGHGHHFHHHGHHGFGGFHHHHHHHHFHHFHHGHHHGGGGGHHHHFFEHHHGGGGGGHFHGEEGF3FEFGHHHHHFFDEEEEHHHGEEGGGGGHFGGDADGFFFFFHHFGHHHFGBHGHHGBCEHDEDDGADCFFHHHGG/:GCCCGHFGHFFGG0CGFGF.FB/9;BFBB0FFBFG0A-..;C:E/.A9.FFFFFFFF9BFFFFFFBFBBB./:BFFF/F;AA?F////
+@M01368:8:000000000-A3GHV:1:1108:25084:18127/1:R1:TTATTATG:R2:CCCTTAAA:F1:TCCT:F2:TAAG
+CAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGAGATAGACCTGTGATCCATCGTGATGTCT
++
+GGGGGGGGGHHHHHGHHHHGFGGFHHHHGHHGGFHEHHHCGGGHBHHHHHHFHHGHHHHGGHHGGHGGGHHHEFHHHHEHGHGGGCFHFHHHHHHHHHHHGHEFGDEGGGHFHHCGGHHGGGGGFGHHGGEGDFHEGG/?GFHGHDGGGGGHHHHADFGGGGGEGCGGGEFGHHFEBFFGGG?GGGGEGGFEFAA?.0:A0;BFFFBFF/;9BFFFFEFF9FBFFB/F/.;FFFF/BB
+@M01368:8:000000000-A3GHV:1:1108:7626:10048/1:R1:ATCAAAGA:R2:AACCTAAA:F1:CAGA:F2:TAGC
+ACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGAA
++
+GGGGGGGGGGHHHHEFEFHHGGGGGGHHHGEF?GGGGGGHHHHHHGGGEGEHHHHGGGGGGGGGGGGGGHHHHHHHHHHHHFFCGHGHHHHGG/BFGDGG2FFHFHGHH0FHFGFHHHHFFHHHHHHHGG<FHHHFGHHGGGGFHHHGGGGGGHGGHGGGHHHHHHFGGGGGGGFFFGGFGGBFGGGGGGGGGGGFGFFFCFFDFFFFFFFFF;./;AAAFFFFFFAFABBFFFB/;;
+@M01368:8:000000000-A3GHV:1:1109:11270:12255/1:R1:AATCAAAG:R2:CTACCTCA:F1:ACAG:F2:GGGT
+TACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAGGTAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTT
++
+GGGGGGGGGGGHHHHFFFHHHGGGFGGFFHGEGCHHGGGGHHHHHHGGGGGGHHGHGGGGGGGGGCEGFCHHHHHGFHFHHHHGFHHGGFHGGGFD/EFGEFFDGFHHGEFCEHFFGHHHGHHHHHHHHHGCGHHHGGFGHHHHGHEHHCFFADGHHHD?CG.CGHBCBFBFFGGFFFGFFFFF.CFBFBCFFFFGFFFFFGGGFFFFFDFAFFFFFF-@DBFFFFBFD---.;BAA.
+@M01368:8:000000000-A3GHV:1:1109:19224:11655/1:R1:AAATAGCC:R2:CCTGTAAT:F1:CACA:F2:ATTG
+GTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGCATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCTGTCTCTTATACACATCTCCGAGCC
++
+GGGGGGGGGHHHHHHHHFHHHHGFGHGGGFFAGFHHHFHHHGHHHHHHHHHHHFHGGHGHHGCFFGHHHGHHHGHHFHGGH3BFFGHHGHGEFFH/EG@-CFGGCC@-;BD?FGGGGGG??FGDAGDFFFFEFF@BAAFEFFBFFFFF?FD9BBFFFF/FFFFBFFFFFFF?FFBFFFF/FBBFFBFFFE?F;@B//AFFFFFFFFF//;BFFEF.BFFFB/;F/99/FBFFBDCF;B
+@M01368:8:000000000-A3GHV:1:1109:21978:9490/1:R1:GGGTCATA:R2:GAATCAAA:F1:AAAC:F2:GACA
+TAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCAGTT
++
+GGGGGGFFGHFGCEGGFHHHHHHHHHGHCBGFEGGHHDEGAFGHGHFGDGBCGHHHHHFHHGHHHHHHHGHHHH1E?EGGGHHHHFGFHFHHHHHEDHHGHH@GGHGHHCGG?CFGFGGGGGFGB.BFGGFFGGFFFBDDBFFFFFF9-;DEFFDFBFFBB.EFF;BFBFFFFFFFFFFFFFFFFFFFFFFFFF/B9/FFFFFFFAFFFF--99AFFFFFFFA;;;FF..9//;/;;/
+@M01368:8:000000000-A3GHV:1:1109:22910:4079/1:R1:TAATAGGA:R2:CTCCGGGC:F1:TGAG:F2:CCAT
+CAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTCCACTTTAGCTA
++
+GGGGGGGGGHHHHHHHHHHHHHHGGGGGHHHHGGEHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGFHHHGGGGGGGHGGGGGGHHHHHHHHHHHHHHHHHGGHHHGGHGGGHHGHGHHHHHHHGFHHHHHHHHHHHHHHHHHHGGHHHHHHHHHHGHHHHHHGGGGGGGGGGGGGGGGGGGGFFGGGGGGGGGGGFFFFFFFFFFFFFFFFFFFCCDFFFFFFF0BFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1109:24217:19077/1:R1:AAAGTGAA:R2:TAATAGGA:F1:CTGT:F2:TGAG
+TCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGCCTTTGATTCCTGCCTCATCCTATTACTGTC
++
+BFFEEGGGGHHGHFHHCFHGHGHHHGF3BFGFHGFEFHFHGH3EGFC1EEGBFGBHFGGFFHHHGHFHGHHGHGGHCEHEBCFF3ED3@GH4FDEG12FFHFFHG/G3FGA/@EFEFCG33FFGBBGHFHH/?BFBGFGFAGC2C/@-;@-;BFFEFADF?DFFFFFF?;AFFA;AD;..FEFFA--;9;D.9BFFBE?;.;///://///99//BB/9;F./B//BBFB9////99/
+@M01368:8:000000000-A3GHV:1:1109:25237:11722/1:R1:CCTGTAAT:R2:CATCACGA:F1:ATTG:F2:TGGA
+ACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATATCGTATGCCGT
++
+5BGGFGABGHGGAEFGFHHHHFHCHFHHBFGGGEHBGGHFFFFGFAEF5FHH?EGGF5AEG3?EBFHD?C/EFHFFEGEE?CFGGGHHFHB3EEFG?EEGHCFGGGGGGGEC<CDFHHHHHE.FD11FFAGBGD.DGHEA<.<<0<EHAHCFHHF./;CC0GFH0::0CFGG0FBFD;9/90BFF0CBBFGB09;B:0;CFF0.-;@AFEEF--;AFFBF/99D-;.//.../9;B-.
+@M01368:8:000000000-A3GHV:1:1109:27103:7153/1:R1:GTAATATT:R2:NTACTTCA:F1:GAAC:F2:GGGT
+TAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGCTGTCTC
++
+CG4EGFG??GACFGGHFHCFHCHBECDEFCEGHHHHHFFGGF3AFFHHFGEGCGHHGEHGFGHHEGG?EFHHH?EGGHHGGGGHHHHHHEGGGGGHFHHGFDDGGACFCC@?/FDDGHHHGHEFFHHH0FDHHFFEDCD.<GGEHGF0CHHHF/CAGC000CCGFHFGFGFFG?:CB990;F09;FB0BBGGGGGG?;A9EBDEFA///;FF/:F?BFBBFFBFFFF///;/9B;///
+@M01368:8:000000000-A3GHV:1:1109:8763:7859/1:R1:TAGTAAGT:R2:GGTTCCTA:F1:ATGT:F2:CTTC
+CGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGCTTTATGC
++
+GGGGGGGFBGFGHHFBHHHHGGHHGGEHGDHHHFGHEHHHHGHHGGGGAGHHFBHHGHFHHHHHHHHGGGCEFGFFFFEHHH?FFG1FFHHFEGGGHGFEEHHHHHGGGFGGGHHHHGGGGG/C/FG-<A<GFHHFFCGHHFHGE0<<CGHHHGCHG.CCCCCE00BBFGFFG.BB0FFBFBCF0;CBFFFEEGBBBFFBF/FFF9BF/9BAFFD9AFEDAA.A/BFFFFFFFFFEB/
+@M01368:8:000000000-A3GHV:1:1110:12808:18367/1:R1:AATTAACA:R2:GCCCACAC:F1:CACT:F2:GTTC
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCCTG
++
+GGGGGGGFGFGHHGGGGGHHHHHHHHGFHHGEGGGHHGFGHEEGGHHHHGHHGFFHHGGGGGHHHHGHGHGHHHFGGFHHGGGGGHHFFFGGHHHE?@EGGHFHEGGGHHGGGGHGEFHHGD?/>CFHHGDFGGGGGEFGC?EGHHHB0CGHHGCGHHHHBEHGHH.::ACA;FECFGGGGGFFFEFGGGGGGGFFBBBFGBFFFEFFFFBFFFFFFBBFBFFB9..AF?FFFFFFF9
+@M01368:8:000000000-A3GHV:1:1110:14751:26540/1:R1:TAACACTT:R2:ATGTTCGC:F1:GGGG:F2:CTGT
+TAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACTGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGTTGTGCACGCGATAGCATTGCGCGACGCTGGCGCCGGCGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTG
++
+EEGFGB1112DGDGHGFGHHCG/ECEBGGHDFGHHFHGHEB1BCGFFE2EGHHGHFFFHHBFFHEFCGGHHFHHHHH111BFFHGHEHBEHGGECEFHGFHFGGDBBGHHBHHHH0GH22FGHGFFFH1BFCG0F@FGG11@GDHFG1D/1FGFHH/FCG.>0><-<@CCFFG.CC-@C?C9FFF0C---;------;9----9-9@-AAFF9B9---9-/;B9BF/9BB//B/;///
+@M01368:8:000000000-A3GHV:1:1110:15519:10008/1:R1:CTGTAATA:R2:GGTTCCTA:F1:TTGA:F2:CTTC
+CGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACC
++
+GGGGGCBGGE?GGGHHHHHGHHBEGGHHGGGGGHHHHHHHHHHHGGHHHHGFGGGGHGHGCFGHHHGGGCGGHGHGGGGGHFGGGHHHHHHGCEFGGHHHHGGGGGGGHGG/CEGHHHHGFHHHGFHHGFFHGHGHFGGEGFDDGGBCGHHGFHH/CHHHHGHGHF0CFGGGGGGGFFFFFBFFFFFFGFFGGF?DGEDEEFEFFFF?FFFFFFFFFFFFFFFBFFF.BFFFBFBBA;
+@M01368:8:000000000-A3GHV:1:1110:16559:7507/1:R1:CATTCAAT:R2:GCCCACAC:F1:TGTT:F2:GTTC
+TTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAACTGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATC
++
+GGGGGGGFGGGGAGHHGCHHGHHHHHHHHHHHGHHGHHHHHHHHHHHHHHHHFGGGHHHHHHHHBDHHHHHGGHFEEGHGGHHHHHHHGHHHEHFGGGGGGHHHF33FGHHG3GDDGH//EEGHHFFBF?GHHFCC@DGFCGGB?DGHAFGGHHGFH0E??<@DGHGGCFGGF?DGGGFFGGGGGGGG.C/0BBF?FBBEGG0FFF.AA9;B9/E////99;;:.//:FFFFBBF//9
+@M01368:8:000000000-A3GHV:1:1110:16700:6843/1:R1:AAATAATA:R2:GTTCCTAC:F1:GGAT:F2:TTCA
+AGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCTGTCTCTTATACACATCTCCGAGCC
++
+GGGGGGGGGHHHHGHHHHHHHHHHHHGGGGGHHHHHGGHGHGGGGGGHHHGFFGHHGGGGHHHHHHCGG@FGHFHFEGGGGGGHGGGGDGHHHHHHHHHHHHHHGHHGHGHHGGGGGCGHEHGHHHFHHHFF.DGHHHHHHGHHHHHHGFGHGCGHGHHHHHHHHGHHHCD?:A::FCDGEGFGFFBFGBFGGGF00CBFFFF/BFBFFFFAE.FBBFBFFFFB/BFFBFFF/ADCAD
+@M01368:8:000000000-A3GHV:1:1110:18014:7856/1:R1:ATAAATAA:R2:CATCACGA:F1:TAGG:F2:TGGA
+TGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGCAAAAAAAAAATAG
++
+GGGCGGGGGGHHHHHGFHHHHHHGHHHGGGGGFHHGHFGGHHHGGFGGGHHGGGGGHHGGGGHGGHHHGGGGGGHHGHGDGGGGGGGGB/A<GFHFHHHGHBBGFEGGGGHFFFEF/EEGGHGGFEHFHHBA.<ADFFHFHB/CCGHFEFHHGHGEFFGGGGGFFFGGFGFFBFFGGBFGG??DGG?@9-ADFFFFB/@BD;./BFE?BFE/>99FE//BBFFF.9/FF?DA=@9./9
+@M01368:8:000000000-A3GHV:1:1110:23303:11846/1:R1:ACTTGGGG:R2:GTCCTACA:F1:GTAG:F2:AGCA
+TAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGTGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTC
++
+GGFBGGBB5AFFFGFHHGGGEGHHHFHHF3EGFHHHHEFHHGGHHHGH3EFHHHHHBDGHHE?ECHGHGHHHHHHFHHHGHHHHHHHGGHGGFHHHFHHGFFHHFEGFHHHHHHEHHFDAGHHHH/BDDFGGH1FDBGHHHHHHHCGHHHFH?0CGCF>CC=@--AFBFFB?=BFDFFF//FDB;-9A-AD-.A.A=?-9-:B/AEB/BFF.A;DDFFFBBFFFF/BBFFFFBFF9B;
+@M01368:8:000000000-A3GHV:1:1111:13195:14562/1:R1:ATCAAAGA:R2:GTATCCGA:F1:CAGA:F2:CATC
+ACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACACATCTCCGAGCCCACGAGA
++
+GGGGGGGGGGHHGG4FDFGFGGCGGGHGHG?EGHEGFFDHFHHHHGGFE@EHHGEEEGFCCEFFGFG/EHHHHHBFBGGHFHFHEHGHEFGGGED/EFDEFFEHHBGHHCFFFDFGGHHGFFFHHHHGFG>0<0DGGFHBGHFBDFGHGFFGGAGHHGCGBHFFHHHFFFBFGGGGF/:FFFCB9F9FF0FEFE?FF0BED-D.//BF9//BBFF/BFFFEFFFFED-DCFF?.:BFA
+@M01368:8:000000000-A3GHV:1:1111:14287:20817/1:R1:GCCAACAC:R2:ATTCAATT:F1:GTTC:F2:GTTA
+CCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTCATCGCACCTACGTTCACTATTACAGGCGAACATACTTATTAAAGTGTGTTAATTAAT
++
+GFGFGGGGGHGHHHHHHHGGGGGHGHFFCGHHGBGHFHHHHAGHHHHEHHAGFFEHEAE?GHHHHEGFFFDGHGHBFFHFHHHGHGHGHBECG@@@EHGGEGCGGGGFFGGGG?BGGGGGG.-C.FEDCFFFEFFFAF/99BEFA.:9BFB/9FFFEFFFFFFEFFF/FBBFFFFFFFFFFFB//;.@@//;DFFFF//BBFFFBF;A;DF=>B//;9B//B/;/;9//9//;B/:B9
+@M01368:8:000000000-A3GHV:1:1111:23624:14516/1:R1:GTCCTACA:R2:CGACATCT:F1:AGCA:F2:GGTT
+TAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGGGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAG
++
+GGGGGGGBGHHHHHHGGHGGHEHGHADFHHHHEGGGHBGHFFHHEHHGHFHGG5FBEEGEGHHHGHHHEFDGHHFFGFGGHHGHHHGHBHGHFHFHHGGGGFCFBGFGE?GFBECEGDGHEHGDGCGHGC/DF@GHGFFCGGGGFFFFDD?@C@GFEC?-ADHFFHBGHFBHFG0CC//.;B0/CA.;AA.;@.AB/9BB/A/.AFFFE/BFFF///9B/FBDE9/;99/B/BFFEF/
+@M01368:8:000000000-A3GHV:1:1111:7437:24508/1:R1:ACACACTT:R2:ACATCACG:F1:TAGT:F2:ATGG
+AGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTGTCTCTTATACACATCTCCGAGCCCACGAG
++
+GGGGGGGGGGGGGHHHHHHHHHHHHHHHHGGGFFEHGGHHHHHHHHHHHGHHGGGGGHHHHHHFHHHHGHHHHGHGGGGGHHHHHGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHGHHGGGGGGGHGGGGGCGHHHHGHHGHHHHHHHEDHHGHGGGGGD;BEGGGFFGGGGC:CFGGGGGGGGGFGGGFFFGFFFFF;FFF;BFFFFFFFFFFFB:FFFFD=CAEEEF>-
+@M01368:8:000000000-A3GHV:1:1111:8665:25542/1:R1:TCCTACTT:R2:CTTTAGTA:F1:CAGG:F2:AGTA
+TCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTGTCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCG
++
+GGFGFFGGGGHGH4AGGGFHHCGEE2FGHHHHHHHHHHGFHGF53FHEGGFAF5CFHHGGFGHFHHGGHHHCHHHHHHHFHHGH?EEEG1FFFEHHFHFGGHHGG?F4FBGHGHCHEF0//-9--;0CFGG?@BGDGFFFFEFBBBDA?FFBFFFF=B;-9.AA9EFFFF/;9BD.//;9/9/B:/:BFBFFBFFF/B:BFF//;/B/FFFBFF.A-BFFFBA/F//BFFFBF/;/A-
+@M01368:8:000000000-A3GHV:1:1111:9655:13916/1:R1:GGCCCATA:R2:TTAGTAAG:F1:ACAC:F2:TATG
+TGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGCGGTGTCCACGCAATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGA
++
+GFE1EEEEGGHGHHH2FGHHHFGFGHGCFGGGEFHGGEGGHHHHGHEFBFEGHHHGHHBEHHHHGHGFHHHGGGGHHEGGGGHHHGFHGHHHH1FHHG?G/AGF1GBFGEFFHF2FDD0FG<GDHBFDGFFCGH//B//?0GFFGFGGHHHFHFB.=1FDFB?FGH.C/.-:::CH0;CAB@-.;0CGFFFGG--9.A@GB>--99@=---AAABA-BF/B?A@F-9BBFF//BB/9/
+@M01368:8:000000000-A3GHV:1:1112:10272:7828/1:R1:GTATCCGA:R2:GTGCTCCG:F1:CATC:F2:GCTC
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTT
++
+GGGGGGGGGHGHHGHGHHHHHHHHHGHHHGGHDGHHHGGGGHHHHHHHHHHHHHHHFHGHHHHGGHGGHHHFHHHHHCGHFFHHHHHHHHHHHHHGHGEFGAEEEEHHGHHGHGHHHHHHHGHHHHHHGHGHFFBC/BA?BGGGFFFFFFFFFFFFFFFC-@DDFFFFFFFEFAFFFFFFBFBFFFFFFFFFFFFFFFFBFF->@FFFFFFFFFFBFBFAD--.99;A?////:.9A.
+@M01368:8:000000000-A3GHV:1:1112:9832:16531/1:R1:CTGTAATA:R2:GTATCCGA:F1:TTGA:F2:CATC
+CGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGGGCTGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCTTGAAGTAGGAACC
++
+4GGGGEBGEFGHGGHGHGHHHGGHFBGFGGGGGHHEFHGEHFHFHEHHHHHGCGGGHFHHCFGHE@1EEEFFGB?EEEEHBGGGCHHGHHBEE@>EAHHFAEBDGGGCEFF?CEGFFHHHHHFHHHFHGHCGCAHHF<..C.D=0CD.GFHHHG.CAGHC:CHB0GGGFFB0:CFA.A-;9.;000CBBFFBFGA.9AA;A;EDDE.ABBFFFF9;BEFFF/BF//9/B//9:B//..
+@M01368:8:000000000-A3GHV:1:1112:9832:6701/1:R1:CGCCTGTA:R2:GCTAAAGT:F1:ATAT:F2:GAAC
+GAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGA
++
+GGFGGGGGGHHHGGHGGHHHHHHHHHHHGHHGGGGGHHHHHHHHHHHHHHHHHHGGCGDHHHHFGGHHHGGGGGFGGHGGGGHHGGGGHHHHHHGGGGGGHHGGGGDGGFGHGGFCDCHHHHGHHHHGHHFAGFGGEHFGEG.C<EGCECEFCFFHBGHE:GHHGFF0FFFB0CFGGGGAGFFF0;;FFGGGFFGFFCDD.DEFBEDD?9FFFFFFFFFFFFFFF/B./FB///;BF/
+@M01368:8:000000000-A3GHV:1:1113:13532:8618/1:R1:GGAATCAA:R2:GCCCATAA:F1:AGAC:F2:CACT
+GATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGCTACAGTTCACTTTAGCTACCTCCAAGTGTTATG
++
+GGGGFBFGGGGGGH5GHFEDHHGGGGCGFBGH?AEEHFFEEGHGHHHHGGG?0EHGHHGGGGGC?GEE/EE?GHHHGBHFHHHHHHGHHGHHHGGGCG/A@<FGGHHHHHHHFF/GFDGHHHHHHGFFFGHGGHABGHFHHHHHFHEGDGHGDDEEHHBEDDEGFGHGBFFBFFEGGGEFGFGFB000;F0F;FGGEGGEFFF;-.9//B///B9FFFFF/BFFB/:.BB//;FBFFF
+@M01368:8:000000000-A3GHV:1:1113:21679:18011/1:R1:GATCACAG:R2:TTAGTAAG:F1:GTCT:F2:TATG
+TCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGAGGGTGTGCACGCGATAGCATTGCGAGACGCTTGAGCCGGAGCACCCTATGTCGCAGTATATGTCTTTGATTCCTGCCTCTTCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAACTGTCTCTTATACACATATCCACGCCCACGAGACTAAGGCGAAGTTCATT
++
+FFFFGGG1FH3GHGHGHGHFHEC?EC0B1FBGFB1GHHH21AF2HH2FEGEHAE10AAE/>/FFHE?/E/?E1@EFFH?E@/EGGG//B11B//<@@C0F/<0<FFDGGCC?FF221<BDD11@<11@DDCGEF1<111F1<F1FBGHGHCF-CHHFA./</0CGHF<0CC/;C-:-;;09;FFBFBBFFBC0FFFGGFC0009C00090/-:--9--;-;AFFE;/99-9--/;///
+@M01368:8:000000000-A3GHV:1:1113:25528:14016/1:R1:CCTACAAG:R2:GTATCCGA:F1:CATT:F2:CATC
+ATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGG
++
+GGGGGGGGGHHFHGHHHHGHHHHHHHHHHHGGGGHHHHFHHHHFHGHHHHGAFFEFHEGHHHHHHHHGHEHHGGFGGGHHHHHHFHHHHHGGHHHHGGGGGHFHHFF?HHGGFECEFFGHFFGFHGECDGHGBGFHGDF@@?CGFHCEGGGFD.CCC?EGHBHHHFHHFBCFFGEB/CEGGGGDAA.90C9CEBFGGBBF/9.9FBFFFBBFF//99FFFFEABF//99FFEFFFBFF
+@M01368:8:000000000-A3GHV:1:1113:5741:16959/1:R1:TAGTAAGT:R2:GTATCCGA:F1:ATGT:F2:CATC
+CGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGA
++
+GGFGGGGGGHHHGHHGGHBGHGAGFFCAFGHGFFGHHGFHHHHHGGGGGHGHHHHHHHHE3BFFHHHGG0EDF@GHFFGGGHGGGGGGGGGGGGGHHGGEEFHGFHHDDG@DGGGHHGDGGGGGHGG?CF?HHGHHHGHGHHHFFHGGGHHHHGGCD.;0<C;CGGGGEFF/.;0;FFFBF/0;0CFGFFB..9B/;0CBFFBBFFFFBAC?DED9;B9AD;.FFFB/B/;FBA/B//
+@M01368:8:000000000-A3GHV:1:1114:10130:11959/1:R1:CGTTCCCC:R2:ATCAGAGA:F1:TTAA:F2:CAGA
+TAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTCTGATCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGCAACAAACACACATCCAGA
++
+FFGGGGFGGD4EGGGGGHHGFFGHFGGHHHFEFHECFHHHEHGAGBCCGCCEGGHGHEGFBFHFHHHHGGGHFHGHEGGGFEGEGG??@DBGHGGC-@FFGHFHFHB-??DA-DD@9:BEBG@B?E?A.ABBFBFA??F.FF/BFFB/B9B/9;BF9FF9FFFFFFFFFFFFFF?BB?;9EE;-;DDB9//;B-B@;ABFFEFFFF/-.9A.;//9/BF./B/..9.9:...//////
+@M01368:8:000000000-A3GHV:1:1114:14540:5315/1:R1:CTTTAGTA:R2:CACTTGGG:F1:AGTA:F2:GGTA
+GTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGGGGGCTATTTAGGTTTTT
++
+GGGGGGGGGHHHHHHHFHHHHGHHGHHGGGHGGHHHHHHHGHHHHHHGGGGGHHFHHHFGHHGGFHHHHHGGGGGHHHGHGGHHHGGGGGGHGHGGGGHHGGGGHHHHHEGDDFGFFFHHGGGGGCDAFCFGFDHHHHGGHGHHHHHHBCGEHHHHGGHG.ACGEHGG0CBFFF:A;BB0;09CGF00CFFFE0AA?//CFFFFFFFFFFFFFFFBEF;A.-=A--:BBFB90;;FE.
+@M01368:8:000000000-A3GHV:1:1114:15066:16302/1:R1:TAAATAAG:R2:TTATTATT:F1:ACAT:F2:ATGT
+ACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAACGGTTGTTAATTAATTATTGCTTGTAGGACA
++
+GGGGGFGGGBGFFFHGFHHGFFFHGHHHGHHHHFFHHHGHGC?AEFFHEFBFFFGHHHHH1FDGFFHGHGHFEGCGC-<<AHHHGGGGGGGFHH0GHFCCCADGGG?.9/A-???DGGFFF.9F9/EE-;;BBBFFBFFFFFFFFFEFFFFBFFBBFFFFF/BFFBFFFFF-DBFFF;/BFF//BB//9/BEA---9:BFFFFFF/F/.;.:@9.BBFF/;BFF/;/////9/////.
+@M01368:8:000000000-A3GHV:1:1114:16639:15258/1:R1:CCTAAATA:R2:TTATTATT:F1:GCCC:F2:ATGT
+CACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGCGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTCCAATATTACAGGCGAACATACTTACTAAATTGTGT
++
+GCGC1BBF1GHHHBHHHHGFHGH1A100AA/GGEHGFBAA1FFD2FHHHHECG2F1BB/E0FC/A>EE/FGGFGEF1EGBBEHHCGGGHBGEHFHE0B?E--;C?CCGGG@A@GBFBBBB09?@??A-AB--ABE@=-=-9AE9A;FFFFFE=9-//;//;9FF/////;;///9B///;/B////9FFBB;--A@-;/9;9-:-/;;FFFE9BF?@;-9-99/B9F/://///99/;
+@M01368:8:000000000-A3GHV:1:1114:2404:13066/1:R1:TCCTACAA:R2:ATGGATCA:F1:GCAT:F2:CAGG
+AATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCTGTCTATTATACACATC
++
+GGGGGGGGGHHHHHGHHHHHHHHHFFHHHHHGGGGHHHHHHHHFHHHHHHFGGHHGGHGGHHHHHHGHHFHHHHGGGGGGHHHHHHGHHHHHHHHHHGGGGGGGHH?FGHHHGGGGGGHHGGFGGHHGGGGHHHHHFGGGGFGHGHHGGGGGGGHGGGEGGHHGHHHHHHHHHGFBFFDA0FGGGFFGG0:EFGGGGGGGG;AEBF0B0BFFBFFFFFFFFFFFFFFFFFFFFFEFF0
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/mec_reads_pair2.fastqsanger
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/mec_reads_pair2.fastqsanger	Fri Oct 08 09:57:12 2021 +0000
@@ -0,0 +1,396 @@
+@M01368:8:000000000-A3GHV:1:1101:6911:8255/2:R1:ATCTGGTT:R2:TCGCCTTA:F1:CCTA:F2:CCGC
+ACTCACCCACGGCGGCCATCAGCCGATACTAAGTTTGGGGTATGGTGGGGGGGATAATGAATTAGGTTGTGGGGGAGGGTTTGTGGTTGAGAGAAACACAAAAAACAATCTTATATATGGGTAGTCGTTTTGTATTGGTTTTTTGTTTTGTTTGTGTTTTGAGTGTCGGTTTAGTTCGGTGTACTAGGGGGGGTGGATGGGGTCGGCTGGTGAGGGGGTCTTAGTGTATTGAGTGTGG
++
+A111A100000000////011110//>>/12@1@22B/////1@>21/>>/-----9/;////9////--;-;-;-----;--------9/-/-///9-;-------9//////9/////-//-/9-;-;9--/////99-;--9-:-;----/---/-----////---9-/////--;A-//////---------9/-----;-----/-/-----;--;//////////9;///-
+@M01368:8:000000000-A3GHV:1:1101:14518:9998/2:R1:GTTATTAT:R2:CATCACGA:F1:TATG:F2:TGGA
+CACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTAATTAATGCTTGTAGGACATAATAATAA
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGFHHHHGGGGGHGFHHHHHHHHHHHHHHHHHHHGHGGEHGGGGCGGGHHGGCGGGGGHHGHHHGGGGGGGG.BFFFGAGADFGAFDGFGGCFFF;DDFFFFFFFFFFFFFFFFFFEFFFFFFFFFFFBFFFFFFFFFFFFFFFFFFF09FFFE00;BE@;DABBFFFFFBBFB00;F:9;FFBFFF9BFFFFFFFFFFFFF90/::BFFFBF0
+@M01368:8:000000000-A3GHV:1:1101:18422:19051/2:R1:GTATCCGA:R2:CTACAAGC:F1:CATC:F2:ATTA
+TTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGG
++
+GGGGGGGGGHHHGHHHHHHHHHHHHHHHHGGGGHHHHHHHHEHHHHHHHGGHHGGHGGHHHHHHHGHGGHHHGGGGGHGHHHHGGGHFHFHHHHHGGGGGHBFFCGDHHHGGGGGGHGGGGGGHHGCGGGFGHHBGGGGGFFFHEGGGGGCDCCE@EFGHHHHFHEGHGFFHHGB;ECBFGGGEFEFFGF0AFGFGFFG.;;DFFFFFFFFFF090BFFFE?FEFBBFBFFFB990BF
+@M01368:8:000000000-A3GHV:1:1101:25545:21098/2:R1:ATTAATTA:R2:GCCCATAA:F1:ACAC:F2:CACT
+GGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTTCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCAACCTATGTCGCAGTATCTGTCTTTGAT
++
+CGGCGGGCGHHHGHHHHCGHFGHFHGFGGCDGGBD5FGFFFHFHGGGHAEBFGHHHEHGGFHBGGFHHHGGGEEFHHHFHFFHDHGHGHHHHFFHHGGFAEGFFFFFBGHHHFFHHHHHHHFHFHHFHGFHGHGA/<@EFHEHH1GGHFFFHG1>=FGHFHGF.GE//-<BB?9.9BFFFB==AA/FFFFFA-@BA.;;D?F9FAB;---./99BFFFBBAE-.9B/BFB9F/9BFBB
+@M01368:8:000000000-A3GHV:1:1101:5446:12248/2:R1:AATTAACA:R2:ATCCGACA:F1:CACT:F2:TCTG
+TTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTT
++
+GGGGGGGGGHHHHHGHHHHHHHHGHHHHHHGHHHHGGGGHHHHHHHHHHHHHHHHHHHHHHGGGGGHHHHHHHGFGHHHHHHHHHHHHHHHHHGHHHHHGGGGGHHHHHHHHHHHHHHHGHHHHHHGHGHGHHGGGGGGGGGGGFFFFFFFFFFFFFFAFFFFFFFFFFFFFBFC?.EAFFFFFFFFAFFFFFFFFFFFFFFFEFFFF0FFFFFFF0BFFFFFFFFF?.BDCFFEDA/
+@M01368:8:000000000-A3GHV:1:1101:5861:6452/2:R1:ATTATGTC:R2:TTATCCGA:F1:CTAC:F2:CATC
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHHHHHHGGGGHHHHHHHHGHHHHHHHHHHHHHGGHGGHHHHHHHGHHHHHHHHHHHHHHHHHHHGGHHHHGGGGGGEHGHHHHHHHHHHHGHHHHHHGHGHGHGGGGCGGGGGFFFFFFFFFFFFFFFFFFFFFFFF?FFEAF:DAEF9DEFFFFFFF-A.BFFFFFEFFFFEFFFFFFFF0FFEB0FFFFBFFFFFFADEFCF0/.
+@M01368:8:000000000-A3GHV:1:1102:10403:6021/2:R1:CGCTCCGG:R2:GGATGAGG:F1:GCCC:F2:CAGG
+ATCAAAGACAGATACTGCGACATAGGGGGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGGGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGAGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACGCTGAAGTAGGAACCAGATGTCGGATACAGTTGACTTTAGGTAACCCA
++
+BGGGGFFCGGHHA5DFGAE?AAEDFHG2AEE1FBE00A1BGE0?E1FFGEEEGB4F43?EE/>///F??//@BCBAC<<BAGHB?11F/FGFGGBFBGBD.11><.<<<C0<A</<<=0GFHC@-.;FF09BFFGB00B0;FE.C/:CCF0;0C0;BBBFF@.9AF.:9EFF.;.BFF/FF/;/./BFB/..;;ABF/9FF//.;AAF9BBBA;-A.B/9///9/BF////;///:9.
+@M01368:8:000000000-A3GHV:1:1102:10677:23253/2:R1:CCTTAAAT:R2:AATTAACA:F1:AAGA:F2:CACT
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGCTGTCTCTTATACACA
++
+GGGGGGGGGHHHHHGGGGHHHHHHHHHHHHHHHHGGHHGGHGGHHHHHHGHGHGHHHGGGGGGGGHHHHHFHHHFHHHHGGGGGGHHGHHGGHHHGGGCGGHFFFGGGHHGGGFHHGHHHGGGCGGHFHHGGGGGGFHGC<@GGHGHHCHE00:CFHHHFGACGFFEG:D.E;FG;EFBBFGGGFEE0CBBBFFGBFFGFGFFFFFFFF0:B0:BFFFFFFF/0.;:0F0B:BFFF00
+@M01368:8:000000000-A3GHV:1:1102:13809:1733/2:R1:ATATTGAA:R2:NATAAAAC:F1:CGTA:F2:CTAA
+TAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATCTGTCTCTTATACACATCTGAC
++
+GGFGGGGGGGGHHHHHHHHHHHHHHHHHHGHHHGGEGGFFHHHHHHGHGHGHHHHHEHFHGHHHHEFHHGHGGGGGHHHHGHHHHHHHHHGFGHHHHHGHGHGHHGGGCCGGGGFGGGGGGDGGGGFGDGGGFFFFFFEFFFFFFFBAF:9AF//;BEF-DD/FFFFBFFFFFFFFFEBFF?FB;/;//BFFEFFE/::..9;-:B9:FBFFFFFFBFB/9/FFF/B///99/:B///
+@M01368:8:000000000-A3GHV:1:1102:17584:10050/2:R1:ATCAAAGA:R2:GTCATAAA:F1:CAGA:F2:ACCT
+AATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTGGAGATCTTGGGGGGTGG
++
+GGGGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHFHGGHGGHHHHHHHHHHHHHHGHHHGGHHHHHHHGGHHHHGGGGGHHHHHHHHHHHHHHGGHHHHHHGHGHGGHGGFGGGGGGGGGGFGGFGGGGGGGGGFFFFFFFFFFEFFCFAAFEFEFFFFFFFCFDFFFFFFEFFFFFFFFFFBFFFFFFF/:BFFFFFFFFFFFFFFFFAFC=@-.;A///B././//////.-9----
+@M01368:8:000000000-A3GHV:1:1102:18842:24844/2:R1:CACTTGGG:R2:CTACAAGC:F1:GGTA:F2:ATTA
+TTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGG
++
+GGGGGGGGGHHHGHHHHHHHHHHHHHHHHGGGGHHHHHHHHFHHHHHGHGHHHGGHGGHHHHGHHHHHHGHHGGGGGHFHHHFGHHHHHHHHHHHGGGGGHHHGFECGGHGGGGGGHHHGGGGHHGGGGHHHHHEFDCADGHHHHGGGGFC?AE-@DDFHFFHHHCFHGGFFGFFFGGGEFEGFGED9C?CEGF90FEF/A./BBF9FFFFFFFFBFFF.9AF////;FFBFFB/:BF
+@M01368:8:000000000-A3GHV:1:1102:21788:11027/2:R1:GCCCACAC:R2:AATTAACA:F1:GTTC:F2:CACT
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCCTG
++
+GGGGGGGGGHHHHHGGGGHHHHHHHHGHHHHHHHGGHHGEHGGHHHHHHHHHHHHHHGGGGEHHHHHHHHHHFFFFFHHHGGGGGHFHGBFEHHHGGGGGGGHHGGGGHGGGGGHHFHHHGGG@CGHHHGGGGGGGGGGGEGDGFFDHHGEHHBCFHGBGFAGGHFGGCEEF0BE<?FFFGFGG<EFFGFFFFGGGGGF:0BFFB9FFFFFFFFFFFFF0B0ABADEF.A/..D.BA.
+@M01368:8:000000000-A3GHV:1:1102:5728:8777/2:R1:ATATTGAA:R2:CACTTGGG:F1:CGTA:F2:AGTA
+CTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCC
++
+GGGGGGDGGHHHHHFHHHGGGGGHHGFHFHHFHHHGGHHHHHHHHHHHHHGHHHHHHFGHHHGGGGHHHHHHHHHGHHHGHHHHFHHHGGHGGHFFHHHHGFHHHHHHHHHHFHFHHHFHFHHHHHGGGGGHGHHHHHGHHHHHHH/FHHHHHGHGGGHHGGFBFFFFFFFFFF;DDFFFFFFF;;BA.=DDBFFFFF;-DFF.EDFFFFFFEF-AFFFFFB;FBFFFBFFFFB9B..
+@M01368:8:000000000-A3GHV:1:1102:5983:21093/2:R1:GTATCCGA:R2:ATTGAACG:F1:CATC:F2:TAGG
+GCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTG
++
+GGGGGGGGGHHHHHHGHHGHHGGGGGHHHHHHGHHHHHGGHHHHGGGGFHHHHGFFHGHGGGFEGGHFFFE?GFFGGGHGHFGHGGGEEFHHHHGGGGGCDGGBGGGGHHHGGHGHHHDGHHHHEFHHHHGF<A.ADGG0EHFFHHHHCEFHHEGHGHHGGHHHFGGGGEF//FFFFGGGFGGGGGGG.ACDE?B?DD9F.BBBBFFFFFEF0090:BF/;:0;0009:A?...0:;0
+@M01368:8:000000000-A3GHV:1:1102:7765:18353/2:R1:CTCCGGGC:R2:ATTATGTC:F1:CCAT:F2:CTAC
+AGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAAAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTT
++
+BEGBGGGGGFHFHHHCFFFGFHHHHF5FEDABFAGGBEE22FFGGEEHF5EDCA11FE5FFE?FEG5EG555F@35B3FFA1FEF2@3GGD3?23?3@F4BF3E>///FDFACF?FHFGC//??1B0<<?/@GFGD/@1FG10<?ACC.<<G0DGGG--.<CCCCGC;CGCGFE9;0FBFA000.;0BF.9....0;909B00999A/9./;BBFB/.:B/////9/999//B//;/;
+@M01368:8:000000000-A3GHV:1:1103:10405:17879/2:R1:GTATCCGA:R2:CTACAAGC:F1:CATC:F2:ATTA
+TTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGG
++
+GGGGGGGGGHHFEHHHHHHHHHHHHGHHHGGGGHHHHHHHHEHHHHHFHGGHHGGHGGHHHHHHHHHHHHHHGGGGGHHHHFHHHFFGHHFGHHHGGGGFHHHHGGGHHGGGGGGGHGHGGGDHGGCGFHHGHHHGGGDGGHHHHGGGGGGGHGG-ADGGHHHBHHHFFFHHHGGGGEGBFGGAEEDBFF0C;CFFGFGFEEFFBBFFEFFFFFFFFFFDEFBFFFF///BFF/BF/A
+@M01368:8:000000000-A3GHV:1:1103:13493:8205/2:R1:GTAGCTAA:R2:AACGTAGG:F1:AGTG:F2:TGCG
+TAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGAT
++
+GGGGGGGGGHHHHHFHHGGGGGHHHHHHHHGHHHHHHHHHGGGGGHFHHGGGHHHGGGGGGHHHGGGDHHGGGGHHHHHHGGFEEEFFHGGGGGGCDHFGCCDGHGHHHHFFFEGHHHFCFEHGHHGG.C.EGGGFGFGEHGHH/:CGHHHGGGB::CGHHHHHGFGBBF0BFGFGGGGBFGGGBG.9.;BEG?AF.FFFFFFFFFFFFBBBFFFFF/BFFEFBBFFEFFFBBB;D9.
+@M01368:8:000000000-A3GHV:1:1103:14060:21273/2:R1:GTATCCGA:R2:TAATAGGA:F1:CATC:F2:TGAG
+CAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACAC
++
+GGGGGGGGGHHHHHHHHHHHHHHGGGGGHHHHEFGGHHGGGGGGGHGGGGDHHGGGGHHHHHHGGGEGFEHHHGGGGGGGAFGGGGBHHHHHHHHHGHHHHHHHGHEHHGGGGAFHFEGGHHFHHHF>FF<F1GGHHHHHHGHHGFFDEHHHHGF0GGHHHGFHGHFAGEGCEBEGF.FFFGGGGGFFGG0CBFBFGGGFFFFFBFFF.E.E?FFFFEFADAF/BFBFFFFFFFFF//
+@M01368:8:000000000-A3GHV:1:1103:14528:12993/2:R1:GCCCATAA:R2:CTTTAGTA:F1:CACT:F2:AGTA
+GTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCCACGTGATGTCTTAGTTAAGGGGAACGGGTGGGCTCTTTAGGTTTTT
++
+GGGGGGGGGHHHGHHHFHGHHHHHGFHHGGHGGGHHHHHHHHHEEHGGGGGGHGHHHHGBGCHFHHHHHHGGGGGHGFHGFGHHHGGEGFGHHEGFFGHFEGG?HEBFHHF?FGGGEDG0CFGGG?E..<<-.CGGHHH0GHEGGDDC0/CA.0G/:;.;.;;;C09;BBFGBA.--./9;0C0/00;0;/./99.:9///:/9//;//;BF.D.AAD.;--@B9../;;:BF/;/..
+@M01368:8:000000000-A3GHV:1:1103:17657:20856/2:R1:AAAGCGAA:R2:CTTTAGTA:F1:CTGT:F2:AGTA
+GTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGAACTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTT
++
+GGGGGGGGGGHHHHGHFHHHHHHHGFGHGEHGGHHHHHHHHHEHFHHGGGGGHFHHHHFHHHHFFHFHHHGGGGDGHHGHFGHGHGGEEFGHHBFGGGHHGGGGHHHHHFFGGGGGHGHGDGCGGCGFF@DGGGHFHH0C.GHFHFHGHHFGH0CCAECDEG0CEGGGGFFFGG;C.0;;00:BF;FFBFFF09A9A:BFFFBFF0BF0:FFFAA;.AAEFFFFEF?FFFEFF9BBE.
+@M01368:8:000000000-A3GHV:1:1103:23099:3794/2:R1:AAGACAGA:R2:CTTCAGGG:F1:TACT:F2:TCAT
+AAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAACACCCTATGTCGCAGTATCTGTCTTCTGTCTCTTATACACATCTGACGCTGCCGACGACCGATCTAGTATAGATCTTGGGTGG
++
+GGGGGGGGGGGBFHHGG?EEHHGHHHHHHGFHFHHHHGHGHHGGHEEHFFFGHGHFGFHHHHHHHHHHHFHFFHGCGHGHGGG/EF3FGHHHHHHGHHHGFGHHHHHGHGFFEHCFGGGGGGGFFFG?FGGGGFFFGFA>>DFCFDFFFFFFFFF-BBAFFFFFFFFE@D9B;FBFFFFFFFFB9/9FFFEBF9/B/BB/BFAADDFFC-;;9-;@@9-.9/://///://///...-
+@M01368:8:000000000-A3GHV:1:1103:25465:20010/2:R1:GACATAGG:R2:AACCTAAA:F1:GTGC:F2:TAGC
+CACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGTGCACCCTATGTCCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTGTAGGTCTTGGTGGTCGTCCTCGTATTTGAACACATAATCGTG
++
+GGGGGGGGGHHHHHHGHHHGFHHHHHHHGGGGGHHHHHGHHHHHHHHEHHHHHGHGGHHGGGHHHHGGGGGHHHHHEHFGEHHHEE14BGHHHGHGHFCE/EFGGGGGGHGGGGGG?FFGGGG.ADGGGFFDA.FFEC--;9BBBD?FFFFFFFFBBFFFFFFFFFFFFFFFFFADFDFFC-BBB;BF-.;9:B9B9/9/;9;//;:.99/;-...:.../;//////.9/////.;.
+@M01368:8:000000000-A3GHV:1:1103:25519:6301/2:R1:AAATAAGA:R2:CTGTAATA:F1:CATC:F2:TTGA
+CGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATGCTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGGGATGTCTTATTTCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTGTAGAT
++
+FFGGGCAFGCGHGGGHGGGHHFHHHFHHGGGGGFFFHHHBHHHHG5BG5GFEEEE1FGFFGF1EGHGGG/BFHEF@EA1BE1@EED3?4DHGGGGEGHFFFDDG?DCDEG@<<ACEHFHHGFDD1FGGGGFHGAGFHGDCAEFGDC0;BGFFBGA/.:GBC0;GBB9FGGGBFEG?.--AEBB00CBFFGBBF0000B09/B/9;/BF/BF.;A..AB;--9-;9-.9A/B///////
+@M01368:8:000000000-A3GHV:1:1103:6074:6549/2:R1:TAACACTT:R2:TTAGTAAG:F1:GGGG:F2:TATG
+TCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+GGGGGGGGGHHHHHGFGHHHHHGDGHGGGGGHHGHHHGHHHHEHHF1EEFHHHHHHHGBGHFFFGFHHEFGC1EFGHFCEFGHDGC/EEGHFCEFEHFEGGEHHHHFFGDGCDGHHEHGD?C@<AC<CF?AF1GHHHHHHHGEHHF<CGFGHHHE?.CEGCCF0.CBBFGF?9:;0FFFE0;FBFBB009CFD?:/FGFBFBBFBF/B//FC.;.:9.;EFF...9FFFFB/:/A///
+@M01368:8:000000000-A3GHV:1:1104:11572:8264/2:R1:GTATCCGA:R2:CATTCAAT:F1:CATC:F2:TGTT
+TTATCATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATC
++
+GGGG5EGGGHHHHHHHHHHHHHHHHHHHHFFHHHFGHHHHHHFHHHGHHHHHDGGGHHHHHHHHHHGGHHHGGEGHGGHGGHHHGFHHHHHGHHHGGGFGHHHHHHGHHEHFHHHHHHGGFGEHGFHGCFHHGGGCFGEFHEGGGFHFGGGGHGHHHHGGGGFGHHGGGG@CGGG.C-C:9BFGGGGGGGGGGEFGFFB.ABFFGDGDF?/;AFFFBBFFFF/A./////;FB//;FB
+@M01368:8:000000000-A3GHV:1:1104:11928:24197/2:R1:ACGTAGGT:R2:CCTCGCTC:F1:GCGA:F2:CGGG
+CCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTAT
++
+GGGGGGGGGHHHHHGGGGGHHHHHHGHHHHBGHHHHHGGGGGHFGHGHHHHHHHHHHHHHHHHGHHHHGGHHHHHHGHHHHGGGGHHHHHHHHHFHHEHHHHHHHHHGGHGGHHHHHHHHFHHHHHHHHHHHHHHHHHHGHHHHHGGGGGHHHHHHHHGHHHHHGGHHHHCHGHGHGCCEGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFFA:.AADEFFFBFEF;DAF:
+@M01368:8:000000000-A3GHV:1:1104:12288:20635/2:R1:CACTTGGG:R2:CCTACAAG:F1:GGTA:F2:CATT
+ATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATGGCTTATTTAAGG
++
+GGGGGGGGGHHHHGHHHHHHHHFHHHFGHF?FGGHGHHGHHHHFHHHHHFEGFHGGHDGHHHHFHHHGHFFHHGAEEGHCEHHHBGHHHBGHFGHHGGGGGFGHHFGCHHCEGE/FGHGHGGGDGGGGGDHFGHHH/E?@DDHBHH>?@DGCAGC-;@DGFFHGCHEEFGGFGFB/;..BBB.CCE?A0FE0EBFF0FEF.;=DFFB//BFBF//;/:9BA.9FB9//;9//;9F;FF
+@M01368:8:000000000-A3GHV:1:1104:13832:4398/2:R1:CACGATGG:R2:GACAGATA:F1:ATCA:F2:CTGC
+ACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTGTAGATCTCGGGGGGTGCCGGCTCATTAAAAAAAGAAGATGTCGAGATGTCAGTGCGTGAGTGGAAGTG
++
+GGGGGGGGGGGGHGGGGGGGHHHGFGGHHFGGGHGHHGHGFGECGHHHHGGGGGGGHEGFGGGHHGHFHHHHFGHFHHHHGHHHHFGGFGG3FFGGHHHHHHH2?FFGHFHHHHHHHHHBGHDGC0FGHHGHHGHHHHHHHHHHFGHHGGGGGHG-:@?FAGA:.:09CB0000;9B0.9-;---:./----.0;B00;:0;;.../90009..-..00000000-...90:.00/00
+@M01368:8:000000000-A3GHV:1:1104:23670:4161/2:R1:ATTCAATT:R2:CGACATCT:F1:GTTA:F2:GGTT
+CTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAA
++
+GGGGGGGGGHHFHHHHHHGHGHHHHHGCHHHHGGGGHHHHHHHHHHHHHHHGHHGHGHGGHGGHGHGGHHGFGHHGHHHEHHGHHHHHGHEHEHHHGGFGGHHHFHHHGHHHHHHHGHHHHG4EGGGFCBBCA?DGGGGGGCCAFFFFFFFFFFFFFFFFFDFFF.9@--=AFFFF;FBFFBEFFF9FBFFB9/FFFFFFB/FFFFFFFBFFFF/BBFBB/FFFE?.;@FFB?FBB//
+@M01368:8:000000000-A3GHV:1:1104:24927:22253/2:R1:AGCTAAAG:R2:GTAATATT:F1:TGAA:F2:GAAC
+TAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGGGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGGGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACGAG
++
+AFGG5GGGGHDGHHHHHHHHHHHHFHCFGC2F3BFGFGHBGHHFHEDHFGGGGGHHHG3F?GHHGGC/EFEHFGAEFFHGGAEHGGGG3EEGEEDHFHAAD@DGGGHG/<C/CHHHHHHEDHFHGHHG0>AC1>GED-<<-.;C0:0C:C;GH:::::0B90;FFGEGFBFF0C.;9F0;0090;900;00FA9D.A...-9=BBFFFE/FE9;9E//BBBB.BBB///B/9/B..;.
+@M01368:8:000000000-A3GHV:1:1104:4705:7727/2:R1:CTACAAGC:R2:TCCTACTT:F1:ATTA:F2:CAGG
+TCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCG
++
+GFGGFGGGGGHHHHFHHHHHHGGGGHHHHHHHHHHHHHHHHHHHHHHEDEFGHFHHHHGHGHHHHHHHGHHHHHHHHFHGHHHHHGGGGGHHHGHHHHHHHHHHHGHHHHFHGHGHGGHGGGDCD.;FFGGGGGGGGFFFFFFFFFFFFF.>FFFFFF-BBEFFFFFBFFFFF-DDFFFFFFEFFFFFFFFFFFF?F///9FFFFF/;FFFFF?AADCFFEFAFFEFFFFFB/;B/A9
+@M01368:8:000000000-A3GHV:1:1104:7756:4776/2:R1:GGCCCATA:R2:CTACAAGC:F1:ACAC:F2:ATTA
+TTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGG
++
+GGGGGGGGFFHHGHHGHHGGHGHHGFHHGGGGGHHHHHHHHGFF3GGGHGGGHFDHEGHHFHHHHGFHBCGHGEGFFFFFHHHHHGHHHHHGHHHGGGGGHHGHHGGHHHGGGGGGHHECCFDHHADGGHHHFGFDC////FHHHDGFCGCDEECF?EGGFFHHFEHFGGHHFFF/A900;C.9..C0990.;CFBFGE/9.9B99/;B.99/FB///9AEF/99/9/BBF/B/B//A
+@M01368:8:000000000-A3GHV:1:1105:11310:21761/2:R1:ATAAATAA:R2:ACTTGGGG:F1:TAGG:F2:GTAG
+TAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCTCC
++
+GGGGGGGGGHHHHHHHHGGGGGHHHHHHHHGHHHHHHHHHGHHHHHHHHGHHHHHHHHHHGGGGGHHHHHHHHHHGHHHHHHHHHHHGGHGGHHHHGHHHDGHHHHHHHHHHHHHHHHHGHHHHHGGGGGGHHHHHGHHHHHHHHFFHHHHHCCAHFHHGGFFFFFFFFFAA;BDDFFFF00.-=D.ABDA-.::AAF;F@.AAD./0000.9-;.9:00009:F090;FF000900;
+@M01368:8:000000000-A3GHV:1:1105:11578:14676/2:R1:ATTGAACG:R2:GCTCCGGG:F1:TAGG:F2:CCCA
+AACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGT
++
+GGGGGGGGGHGGGGGHHHHHHHGHHHHGHHHHHFFFGGHGHHHHHHHHHHHHHHHHFGHHHHHHHGHHGHFHFGHHHGGGGHHHHHHHHHHHHHHFHHHHHHHGGHGGHHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHDGGCGHHHHHHHHHHHHHFF<GGHHHHGFGHGEHGGA=A=DFFFFAFAFF?FFFFFFFFFADFAAD;FFFA:BBBAE.A.EBFFFFEF-..0BFFF9
+@M01368:8:000000000-A3GHV:1:1105:13575:19255/2:R1:TTAGTAAG:R2:GGTTCCTA:F1:TATG:F2:CTTC
+GGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTGGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTAACTATTACAG
++
+FDGFGFDGDEG1EGEFFBFHFGHA0E00A0CAAC0FFDFFAGHFEHHFDH/EAFCFFHACGHHAFFEF2DFFG/FGHHHHGHGH0C@/E@GGC0FG10>GGFGHHGHFFBGFGB2>F<EEF0@C@9:AAF00;9@-9.;FBBBBB->@;-A@FF<-;---@-;-----;-BFF/;---9//BBFFFF//B;FF///9BF///;/;B/BBFBFFBB/;-9--///;9/:-;BFFBBB9F
+@M01368:8:000000000-A3GHV:1:1105:15502:11453/2:R1:GTCCTACA:R2:GATCACAG:F1:AGCA:F2:GTCT
+TCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTAATTAATGCTTGTAGGACCTGTCTCTTATACACATCTG
++
+GGGGGGGGGHHHHHHGHHHHHGGGGGFHFHHHHHHGHHHHHGHHHHHHGHFHGHGGGGGGGGHHHGGGGGGGGHHHGHGGGGGGGGGGGHHGGGFGGGFEGGGGFFFGGFGDGGGBFGFFFFFFFFFFFFFE0BFFFFFFFFFFFFFFFFFFF;BFFDFFFFBF0BFFBFFEEBFFAA009FFFFFBFFEBB0;.BFFBFFFFFFFFFFFF0;BFFFFE//090::B0000:009900
+@M01368:8:000000000-A3GHV:1:1105:16787:9771/2:R1:GTTATTAT:R2:TCCTACTT:F1:TATG:F2:CAGG
+TCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCG
++
+GGGGGGGGGGHHHHHHHHHHHGGGGHHHHHHHHHHHHHHFHHHHHHHGGFGGHHEHHHHHAGHHGHBHHHGHHHHHHGHGHGHHHGGGGGHHHHHHHHHHHHHHHFFHHHHHGHGHGHHGGGACAFGGGGGG-AFGGFFFFFFFFFFFFFFFFFFFFF-9@AFEDFFFFFB.9-AABBBFFFEFFFFFFFFBFFFFFFEBB0BBBFFBFFBFBEDEAFFEB.ABFBFBFFFF0::/.-
+@M01368:8:000000000-A3GHV:1:1105:17564:15723/2:R1:TATGCTCG:R2:ATCCGACA:F1:CCTG:F2:TCTG
+TTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTT
++
+GGGGGGGGGHHHHGHHGHHHHHHGHHHHHHFHHHHGGGGHHGHFHHHHHHHFHHHHHHHGHGGHGGHGHHHHFHFHHGHHHHHHHHHHHHHEHGHHHHHGGGGGHHHHGEHHGHHHHHHGHFGHFHGGAHGGHGGGCCBDFGFFAFDBDDFFFFFBDA;AAD-ADC?AFEFB-@@AAEFEFFFFF..-:.B0:FFFFFFEF0BFF09FF.0;9BFFFFF0BFFFFFF?.::-909;.9
+@M01368:8:000000000-A3GHV:1:1105:18108:12091/2:R1:TAATAGGA:R2:GTATCCGA:F1:TGAG:F2:CATC
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTACTGTCTCTTATACAC
++
+GGGGGGGGGHHGHHHHFHHHHHHFHGHHHHFHFHHHHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHGHHHHGHFHGHHGHHHHHHGHHHHHHGHHHHHGGGGGHHHHHHHHGHHHHHGFGHHHHHGHDHGHHGCA;?AAFGFEFDFFF.FFFFEBDFFFFFFFFBFFFFFFFFFEFEFFFEFFFFFFF.:BFFF0BFFFFFFFFFFFF;0FF0;BFFFFFFFFBFFFBFEFFFF0
+@M01368:8:000000000-A3GHV:1:1105:18331:16683/2:R1:TCTGGTTC:R2:TTATTATG:F1:CTAC:F2:TCCT
+CAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGGGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATATCT
++
+GGGGGGGGGHHHHHHHHHHHHHGHHHHHFHGHHGHHHHHGGFGHHIIHHIHHHHHHHFHCFGHEEHFFHGHHFGHGHGHFHHGGGGGGEEGHHEHFHHGGHFHHFGGGGDFGBCGG?DGHGGFCGGHHECEF?CHGGDGFFGGHHC?EEGGHHHH.>AEGGGHEE-AEG0C0GCCEFFFFGEFG/;CEGGGE.:CAE.;@.@EFBFFFF/..:BFF0:BB00FBFFFFBDAFFF0;0B
+@M01368:8:000000000-A3GHV:1:1105:20577:18421/2:R1:GGGGGTAG:R2:ATGTCCTA:F1:CTAA:F2:CAAG
+ATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGCCGAAAATACCAAATGCATGGAGAGCTCCCGTGAATGGGTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTT
++
+CFFGGGFGGHHHHHHHCEGHHCHFGHCAFEFHHHGGAEGGHHDHHHBGHBGHHH?5BGE1AEEFHHHHHGHFHBGHGEGGGGHBFHHFGHBGCFFG4EGHGG?E/FG3F3F/FGCDECEA/FGG/CEDBB//?BHEHHF0ADC@<AFH1CDDGCGG..<C--:D000CF0::C009B9F/B..909C9....009.;;/900:A;;A////:BFFF/BFBFFFF.9.//;999//;9/
+@M01368:8:000000000-A3GHV:1:1105:21099:2895/2:R1:TAGCTAAA:R2:TTATTATT:F1:GTGA:F2:ATGT
+CTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATCGACCTGTGATCCATCGTGAGG
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGHHHHFHFHHHHHHHHDEGGGHHIIHHIHEGDFHFC1EAFHFFHEGHHGHFHHGHFHFFFFGGGGHGHFFGFHEGHHGHHHHHGGGGGHECFGADHFHGGCGGEGHG/EGFHHGGDGHFHFFCECC@E?F1FH?ECGGGGHFCAEAFFHBC0CACF0BFFGGGGGFB:BEFEDGD0::;9FBB0:BF9@=...;9-AB;B0;F00:;.9:/..
+@M01368:8:000000000-A3GHV:1:1105:26469:19245/2:R1:TTATGATT:R2:GGGGTAGC:F1:ATGT:F2:TAAA
+TGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTTGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCT
++
+GGGGGGGGGHHHGGGGGHHFFGHHHHFHHHFFHFHHHFHHHHHFGFHHHHHGHHHHGGGGHHHGHHFHHHHHHHGHHHHHHHGGHGGHHHHHHHHHHHGHHHHHHHHHHGHHHHGHGHHGGCGGGHHHH23FFHHHHGHGCGHHHHGGHFHGHBCCFFFFFFF/ECCDFDFEFFFFBDAFF?DADE??BFFFF=A-.AAAA.BFFFFED..BF/BFFEFFFFBFFFFFFFFFFBFB::
+@M01368:8:000000000-A3GHV:1:1105:7169:17145/2:R1:AACCTAAA:R2:CATTCAAT:F1:TAGC:F2:TGTT
+TTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGGTAATAGGGGGATAGACCTGTGATC
++
+GGGGGGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHHHHFHHHHHHHGGGGHHHHHHHHBGHHHHGFDGFHGGHGGHHHHHHHHHGHHHHGGGGGHGFHHHEHHHGFGHHHHGGGGGGHEHH3FGHHHGGGGGGHHECEGDFGFCGDHHHHFGGGC?@?CDGHGGGGC-:.ECDGDGGGGGF0.00BFGGGF/BD.00FG..;9.9;E.;BFFFFFF.9-.99///9BB///;
+@M01368:8:000000000-A3GHV:1:1106:15481:16176/2:R1:CTTTAGTA:R2:AAAGTGAA:F1:AGTA:F2:CTGT
+TCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTAT
++
+GGGGGGFGGHHHHHHHHFHHHFHHHHGHHHHHHHHGHHHGHHEGHHHGDGCHHHHHHHHHGEHEHHHHHHHFHGGEGGHHHHHHHGEGHGHHDHHHHHHHHEHFHGHGHHHGEGCEHHFHHHGHHHHHHHF?GHHHFEFFAFFHHGG?;@DDFFB?@B;BDAFFFEBBD>D>D9@DDCFFFFFFCFDFE.AA;/BB/.;-.;BFBBBFFBFFFFFFF/9FF?/;/BBFFFFF/;FFB/
+@M01368:8:000000000-A3GHV:1:1106:17389:18671/2:R1:CCATAACA:R2:GTATGTTC:F1:CTTG:F2:GCCT
+TAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTCTTTAGGGTTTATGACCCTGA
++
+GGGGGGGGGHGHGHHGFGFGFHGGHHGHHHHHHHHFHHGGGGAGFBGHHHFBBGH5GDHH5EEEGEHEGFBF1DGFDGFGGGBBCEEGEHFEFDDHFBFHFD/@BGDGDHHGDCCFCD/C<->.ADDGE1GA<DBGFGHBG/..DGFCDGD.:0:.;CFGHEHBF.A-99CFGGFF0C0C0BF0;CA9/B:///;//BF/9B9?-..:;.;9.9A././;B//F.B?A////9;:/:/
+@M01368:8:000000000-A3GHV:1:1106:22927:3863/2:R1:GTATCCGA:R2:AAGACAGA:F1:CATC:F2:TACT
+CGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGG
++
+GGGGGFGGGHHGGHHHGGGGGGHGHGDFGHFGGGGFHHHHHGGGGGGGGFHGDFGGGGHGG?@EFHGEFEHEGFHHHHHF2FEHHGHGDCEAD?GFDFGGHBGHHFEHHHHHHHHHDFGHGHHGBDFG0FFHFGGFHHH=GGBF-AACEHEHHGGGHHHGHHFHCCFEBB0FFFFFF/;0;;FFFBFE.AA0BF0??-AD/////;:BFFBFFBBBFFFFFB/.9ADDAD-D;-;=A-
+@M01368:8:000000000-A3GHV:1:1106:23625:4236/2:R1:TAGCTAAA:R2:CACTTTAG:F1:GTGA:F2:TAAG
+ATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGGGTGGGCTATTTAGGTTT
++
+GGGGGGGGGGHHHHHHHHGHGGHHHHGFGGG?HGGHHHHHHHGGHGFGHGEEGFHHHHHHHHHHHFHHFHHGGCGGGHHHHBFGFFHGGGEFGHHGFFEEFHGGDGEHFHHHGGGCCCGHHG?EGFGGGFED@D?CEDFHEHGHFFHFHHGCGG.:CGGD:AEDCG?C?BFFFGGG/CEFBFEFFF/;:BBB;CFGD.:/:B:BB/BFFFBBFBFFAA9A..9-9@:/./;B/9/:/;
+@M01368:8:000000000-A3GHV:1:1106:26031:14826/2:R1:GATCACAG:R2:CTGTAATA:F1:GTCT:F2:TTGA
+CGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGACCTAGTGGTGATATAGGGGTGTCCCGCGTT
++
+GGGGGGFGGGGHGGHHHHHHHGFFHHCHGGGGGHHHHHHFHFFGFGHHHHHG0EEEHHGHFFGFFHGGGCFGEFHGGGGGHGFEEGEFHGHFFGFGGGGFGDGGGG?DCCCCCDDFGHHFHCGHGHHGHHFBAFGGHE.<DCDD<CD;GFFEFHH.@?A//B0F0/;09CFFBBCF0;;F;B0;009FBFFB9.9ADDFFFFAACAC;-9;BB/B././9//;//...-;///---;9
+@M01368:8:000000000-A3GHV:1:1106:27607:15990/2:R1:GACAGATA:R2:CCCCTTAA:F1:CTGC:F2:ATAA
+ACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTTGAGAACTCGGGGGTTGCCCTGTCATTCACAAACAAACACATAGCACTCAAG
++
+GGGGGGGGGHGGHHHGHHHHGHHFHHHHHHGHHHHHHHHGGHHHHGGGGFHHHHHHGHHHHHHHHFGHHHHHCHGHGHHGGGGGGGHGFFGG@CEDGHHFHHCFGBDDGGG?AFGFGGGGAEAFDFFFFFFFECFAFFFFFFFFFFFFFFFFFFFBFFEFFFFFFFFFFDAD;=DADFF-.A.BB0000;.00;:..-;----.000.;000;00009...;A.A..0000000//00
+@M01368:8:000000000-A3GHV:1:1106:6455:17124/2:R1:GTATCCGA:R2:GCATTAAT:F1:CATC:F2:TAAT
+AACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGG
++
+GGGGGGGGGHGHHHHHDGGHHHHGGGGHHHHHHHHFFHFHHHFGFGHGGHGGHHHHHFHHHGGGHHGGGGGHFFHHFHHGHHHFHHHHHGGCEGHGHHHGGHFGGGGGGGHHFGGC/CGGGADHHHHFGGGG?DCFHHHFGFGGCEHECACDGEHHFCGH0CFHHHHHFHFEBFFED.EED0CE0C0CFGGGGGA.;CBBBFBF/BFFFFFFEA;FFFF/BBFF//BBFBFFD.:9A.
+@M01368:8:000000000-A3GHV:1:1107:14451:26748/2:R1:GTATGTTC:R2:AGCTAAAG:F1:GCCT:F2:TGAA
+TGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTAT
++
+GGGGGGGGGGGGHHHHHGGHHHHHHHHHHHGHHHHHHHGGHHHHGHHFHHHGGGGHHHHHHHHHHGHHHHHGHHHFHGGHGGFHHHHHFGFGFHHHHHHHHHHHHFHHHFFHHHHGGGGGGGFFHHGGHHHHHHHFHHHHHGGFDHGHGGGGBFFFFFBAD@>;9.FFFFFFD-99ADFFD-.9FADF--9..;AAFEFFEAA-;.///BB:BBF/BBB//B//99/;BBB/9////F
+@M01368:8:000000000-A3GHV:1:1107:18714:24788/2:R1:GTATGTTC:R2:GGCCCATA:F1:GCCT:F2:ACAC
+TGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTAGGTCGCAGGAACTGTCCTTGT
++
+GGGGGGEGGHHHHGGFFHHHHHHHHHHGGGGGHHHHGHHHHHHHHHHHHHFHHHHHHHHGHHHHHHGHHHHGGCGHHHHHHHHHHHHHHHGHHHHHGDGHGGHHHHHHHHGHHHHHHHHHHHGHHHHHHEHHHGHFGGGGHHHHEHFHHGHFHHF.>GGHHHGHGHGGHCFFCDFDFFFFFFAAF.FFFFFEFAFCFFA..@.AFFFC9--9;.;A///00--;A-.;.000000090
+@M01368:8:000000000-A3GHV:1:1107:21355:8333/2:R1:ATATTGAA:R2:GTATCCGA:F1:CGTA:F2:CATC
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCGGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGHHHGHHHFHHHHHHGHGHHHHHHGHHHHGGGGHHHHHHHHHFFHHFHGHHHHHHGGHGGHHHGHHHHGGHFHHHHHHHFHHGHHGEFFHFHHGGGGGGHHHFHHHHGHHHHE?FGHHHHGFGHGHHGGGDGGGGGFFFCFFFFFFFFFFFFA;DBBDFFFAFFFF;DBAFEDFFFFFEA?-9...9;9;BFFFF//BFBFFFFBFBFFFFFB/BFFF9B/EDEF-BFF.
+@M01368:8:000000000-A3GHV:1:1107:22864:15712/2:R1:AATAAGAC:R2:GTAATATT:F1:ATCA:F2:GAAC
+TAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTCTGTCTCTTATACACATCTGACGCTGCCGCCGAGGGCTCTAGTTGTGGTCTG
++
+GGGGGGGGGGGGHHHHHHHHHHGHHHGGGGFHGHHHHGHFGFFFFGGHGGGGGCHFHFAFEDHHGGFGGGHHEGEGGHHEGGCHGHHHHGGGGGGHGF0EECGGGGFECCFFGFBGHHHHHHGGHHGHFCFEHFBEFGGADDDC=CC0CCFHG:CEHHHGHBGH:GFFGFF0CAAA/BF09BBBBBBB9CFFB0C00;000;:CFFB;:...D?>:@=:9-@...//;////..;/;/
+@M01368:8:000000000-A3GHV:1:1107:24817:14233/2:R1:CTTCAGGG:R2:CTTTAGTA:F1:TCAT:F2:AGTA
+GTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAAAGTGTGGGCTATTTAGGTTTTT
++
+GGGGGGGGGFHHHHHHHHHHHHHHGHHHGEHGGHHGHHHHHGHHEHHGGGGEHGHHHGEHHGHHDGHHHHGGGGGFGEFGGEGHHGCEEEGHHEFGGDHGGGGAGFHHHHGGF/?//GHFFDGGGGGHAD??DC1DHHBGHHHHGHF<<//ACFHHCDCDE?CGEBEGFFFGF?.?DGGGGEFEFFB00CFFFB.:AFFB;/BB9BBFFBBFFFAD.;///9.A./A:FB;BF//B..
+@M01368:8:000000000-A3GHV:1:1107:24830:14440/2:R1:AACTGTAT:R2:CTTTAGTA:F1:CCGA:F2:AGTA
+GTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTAGTTAGGTTTTT
++
+DGGGGGGGGHHHHHHHFGHHHHHHGHHHGGHGGHHHHHHGHHHFHHHGGGGGHHHHHGHHHHHHHHHHHHGGGGGHGHHFGGHHHGGGCGGGHHGGG?GGFGGGHHFHGH?FG/CDHHFAAEGGG/DHFC?-.AFGFH0CHHFH0DHHG/CDEBFHG.CA.:0C:;.FGFEFFG:E.B909BFF/;CFGBB9BBA.:CFGFFFFFFFF/;//AF?.ADEAB.9.A/;.:BFFF/9FF.
+@M01368:8:000000000-A3GHV:1:1107:26478:23602/2:R1:GCTAAAGT:R2:ATCAAAGA:F1:GAAC:F2:CAGA
+ACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGCGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTTCACTTTAGCCTGTCTCTTATACACATCTG
++
+GGGGGGGGGGGFHHEFGHHHGGGGGGHHHCGGEFHFGGGFHHHHHGGGEGGHHFHEEGEG/EEEE/?/EHFHH3GGH4EGHHCB01CGHGHGD//<@CGGBFFDGHHHH0FEHHGEGFHCD11>0=GGHGCCFGHGBGGD0GGHC0C.@?ACEEC/.EDEB?BFFCFB9CFF090BBCBFBF0CCB0B00A.9E.B/9BA=-..B9FBF//;BBBBFFB:./9/9/9;B//9BF/;B/
+@M01368:8:000000000-A3GHV:1:1108:11059:23181/2:R1:GTTATTAT:R2:AACTGTAT:F1:TATG:F2:CCGA
+ATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACC
++
+GGGGGGGGGHHHHHHHHHHHGHHHHHHHHGHHHHHHHHHHHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHHHHHHHFHHHHHHHHHHHHHHHHGHGHEHHGFCGGGHHHHHHHHHHHHHHHFGHHHHHGHGHGHHGGGBFGFFFFEAFFFA.BFFFEFDDFFFFFFFFFFEEFF;D;EFFFFFF0BFFFADDFFFFFBFBFFFFFBB0FFFF0::0BF000BFFFBBF0EDFF@
+@M01368:8:000000000-A3GHV:1:1108:12233:13498/2:R1:TAGGTGCG:R2:GGTTCCTA:F1:ATAA:F2:CTTC
+GGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACTGTCTCTTATACAC
++
+GGGGGGGGGHHHGHHHHHHBGHHHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHGHHHHHGGHHGHHHHHHGHHHHHHHGGHHHHGGGGGHHHHHHHHHHHHHGHGHHHHHHGHGHGGHGGGGAGGFGGGGGGGGFFFFFFFFFFDFFFFDFFFFFFFFF>.AEDEFFFFF?E-DAB9FFFFFFFEF:FBFB009:0FFFF9BFFBFFFFBB0.9A=-/0BFF0BBFFBFF:90:
+@M01368:8:000000000-A3GHV:1:1108:14328:14751/2:R1:ATAATAGG:R2:GTATCCGA:F1:ATGA:F2:CATC
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATCTGTCTCTTATACA
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHDHHHHGGGGHHHHHHHHHHHHGHHHHHHHHHGGHGGHGGHHHHHGHHHHHHHHHHHHHHHHFHGHHHHHGGGGGHHHHHGHGHHHHHHG?FHHHFHGHGHGHHGGGGGGGGGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFAFFE.ADEFFFFFFFADFFFFF///BBFF/FFFFFBFAFFFFBB///;9:BBFFFBF9B9//:/
+@M01368:8:000000000-A3GHV:1:1108:16350:22621/2:R1:TTAGTAAG:R2:CATCTGGT:F1:TATG:F2:TCCT
+CTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATAT
++
+GGGGCGGGGHHHHHHHHGHHHHGHGHHHHGGGGHHHHHHHHHHHIHHHGHHHHHHGGHGGHHHHGHGHGHHHHHHHHHHHGHHHHHHGGHHHHGGGGGHHHHHHHHHHHHHGHGHHHGHHGGGGGHHGGGDADDGFFGGGGFFFFFFFFFDFFFDFFFFFFFFFFFAFAEFEDFFFFFFEE-AAFFFFFBFFFFF0FFFBFF;AFFFFFFFFFFFFFFFFFFFFFAB9BFFFFFBFFF
+@M01368:8:000000000-A3GHV:1:1108:21791:23272/2:R1:CTTTAGTA:R2:CATAACAC:F1:AGTA:F2:TTGG
+GGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCT
++
+GGGGGGGGGHHHHGGHHHHHHHGGGEGGHHFGDHGHHHHHHGGHHH2GGHHHGHHGGGGFGFBFHHHGGGGHGHGHHHHHHHHHHGHGHHGHHGGHGGHHHHGGFHGGGHFHGHHHHHGGHHHGHGFCGFFDGGG/FCFHBGHHHHHHHGHCHHHHGGGHGHGHGCFF;>@DFFBFFFFFFDFFFFFFFF;;.DDAA;FFF;BB;C@..9::BBFBBA;-:.::FBB///;/////:/
+@M01368:8:000000000-A3GHV:1:1108:23314:26089/2:R1:ATTGAACG:R2:CATAACAC:F1:TAGG:F2:TTGG
+GGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCC
++
+GGGGGGGGGHHGDHHHHHFHHHHGGGGGFHFFGFFHEGHHHHHHHHFGHFHHHHDEHHHHHHGHFHHGGGGHHGFHHHHHHHHHHHHHHHHHHF?EEFCHFGFHHEFFFHGFHHGHFHFHHHFFHAG??GHACGGDGHGGBFHHHHHHHGHFGHGHGEGHGCFFF@CD-BDDFFFFFFFFDDFFBBFFD-B-A.DFFA.AFEFF-;-..:..BFFFFFA-../9FFF//B/BBBBFF/
+@M01368:8:000000000-A3GHV:1:1108:25084:18127/2:R1:TTATTATG:R2:CCCTTAAA:F1:TCCT:F2:TAAG
+CATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTAATTAATGCTTGTAG
++
+GGGGGGGGGGGHHHHHHHHFHHHHHHHHHHHHHHGGHHGHHHHHGGGGFHHHHHFHHHHHHHHHGGHHHHHCGGHGHHGGGGGGGHHGGGGGGGGHHHGHHGGGGGGGGGGGGGGGG@CDE?EFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFFFFFFFFE;DFBFFFFFFFFFFFFFFFFFFFAFFFFFFFBFFE0BBBFFFFFFFFFFBFFFF9BB0:0:B;
+@M01368:8:000000000-A3GHV:1:1108:7626:10048/2:R1:ATCAAAGA:R2:AACCTAAA:F1:CAGA:F2:TAGC
+CACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTGGAGATCTCTGGGGTCGGCGGATTT
++
+GGGGGGGGGHHHHHHHHHHHHHHHHHHHGGGGGHHHHHHHHFGHHHHHHHHHHHHGHHHHGGFHHHFGGGGHHHGHHHHHHHHHHHFGHHHHHGHGHGHHGCGCGGFHHHGGGGGGGGGGGGGGGGGGGFFFAFFFFFFAA-AFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBBFFDFFFFFB-<>;>@BE<:000.0.0/0<00<0:>..-<<<---.0
+@M01368:8:000000000-A3GHV:1:1109:11270:12255/2:R1:AATCAAAG:R2:CTACCTCA:F1:ACAG:F2:GGGT
+ATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTGGAGATT
++
+GGGGGGGGGHHHHHFHHHHGGGGHHHHHHHHHHHHHHHHHHHHGHGGHGGHHGHHHHHGHHHHHHHHHFHHHHHGHHGHHHHHGGGGGHHHHHHHHGHHHHHH?FHHHHHGHGHGHHGGGGGGGGGGGGGGGGGGGGFFFFFFFFFFFFFFFFECADFFFF.DEBFFFFFF;D.B<FFFBFFFFFFFFFFFF0FBFFFFFFFFFFFFFFFBDDDFEFDFF@--@-9.<:000.0<0<0
+@M01368:8:000000000-A3GHV:1:1109:19224:11655/2:R1:AAATAGCC:R2:CCTGTAAT:F1:CACA:F2:ATTG
+ACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTCTGTCTCTTATACACATCTGAGCTTC
++
+GGGFGGGGGHGGHGGGHHHHHHHHHHHHHGGGGGHFHHHHHHFHHHHHFHHHGGGGGHEFHCEEHHHGGGGFGGGFGGGGHEGGGEHFHHHHDGGF?AGFHGGGGGGGGHGGGGGGGHHHHHHGFFFHHHHFCEFHFHGF<EGFHFGGAGBFHHHG/C.;C:0:GGG00CFGEFGBA.9C:BBFFGFGGFFFBFGAGG.D..:A.DFFEFFFBFFF0099:9BB0BFB009000;000
+@M01368:8:000000000-A3GHV:1:1109:21978:9490/2:R1:GGGTCATA:R2:GAATCAAA:F1:AAAC:F2:GACA
+ATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGGTCCAGTGTAGAGTTATGGGG
++
+GGGGGGGGGGGGHHHGHGGHHHGGGGGGGFHGGGGHHGGGGHHHHHHGGGGG?HHHGGGGGG?E1FEEE?EHHHHFHAGHHHHHHHHHFHHHHGGFDEG2FCFFGHHHHFH?FF<FFGDHHHHBGHHEGFDD<GFGFDBGHGGHH0GDFH@<AEE.::CFGGHGGBGFGG0BFAF0000BFDEGGFGGGGGFGE00BC;;B00.;AAD.;--------.-;/:9////////////;9
+@M01368:8:000000000-A3GHV:1:1109:22910:4079/2:R1:TAATAGGA:R2:CTCCGGGC:F1:TGAG:F2:CCAT
+ACACTTGGGGTAGCTAAAGTGGACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCT
++
+GGGGGGGGGGEGGHHHHHHGHHHHGHHHHHHGGGFGHGFHHHHHHHHHHHHHHHFHGHHHHHGGHHHHHHBGHHGGCGGHEHHHFHHHHFHHFHHHHHHGHGGHGGHHHHHHHHHGHHFFHHHHHGHHHHHHHGHHGHHGG?FGHHGHHHHHHHHHHHGGHHHHHH?CEHGFHGGF--@DFFFFFAA;DDFFFFFF?@FC.A=DD-.AFFFF;->;.ED.FFFFFFF-.:00009BBF
+@M01368:8:000000000-A3GHV:1:1109:24217:19077/2:R1:AAAGTGAA:R2:TAATAGGA:F1:CTGT:F2:TGAG
+CAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGAACCTGAAGTAGGAACCAGATGTCGGATACAGTTCACTTTCTGTC
++
+FEGGCFGFGHHHHFHHFHHHHHHGGEEEFGHGFFAGFFEEAEGGHHBEEFAFGAEF1G3GFGGEEF@EAGGHGFF?ECGGHEEEFGGHHHHFHHFHHGFHHHC2D<FFFFAFDFF<FF1FGGBHHFF0>AGHGG00<G<<DGBGDD0<.;CGG;;:;CFFHHHHHHG?D.;.;/ACD.;FFFB0CFBFGGFGGB0;EFAFF9B/:BB/;;AEFF//:AF-A.;//:B///;BFBB:;/
+@M01368:8:000000000-A3GHV:1:1109:25237:11722/2:R1:CCTGTAAT:R2:CATCACGA:F1:ATTG:F2:TGGA
+CACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTGTCGATCTCTGTG
++
+GGGGGGGGGHHHHHHHHHHHHHHGHGHHHHHGGGGGHHHHHHHHHHHGHHHAGHHHHHGHGHGHGGGGCGF?FHGGGGGGGGHHHGHHGGGFFGGGGGGGGGGGGGGGE?DEGGGFFEF;DDFFFFFFFEFFFEFFFFFFE./B9BFFFBFFFFFFFFFFFF>-BFFA9FFFFFFFFFFFBFAFFAFFFFFBFFFFFFF/9BFFDFFDDFF-9@CDAD;:AFF/;B//....;;///;
+@M01368:8:000000000-A3GHV:1:1109:27103:7153/2:R1:GTAATATT:R2:NTACTTCA:F1:GAAC:F2:GGGT
+NTAAAACCTNAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCANGGNAGCTCTCCNNGNNNNTGGTATTNTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACCTGTCTC
++
+#AAFFGGGG#BAFFAGHHHGGGGHGHHHHFHHHHHHHGHHHHHHHEGFGGHHBGHGHHBGFFEG2GHHFHFHHHGHHGHFH#/B#??FFGHHH##?####????FHG#??CFGGGEF>CGAGAGGGFGAA@@FFFFFFFFB=@@FF?FF;FFFF@@-@-AFEF?BB/BF?E-BBFFF;:BB/BFFFB/BFFFBFBFBBFFFFFB/FFFBB/;9A@@BFFBFFFF/BBFFFFFFE/:9/
+@M01368:8:000000000-A3GHV:1:1109:8763:7859/2:R1:TAGTAAGT:R2:GGTTCCTA:F1:ATGT:F2:CTTC
+GGGTCATAAAGCCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAG
++
+GGGGGGGGGHHHHHHHCHFAFHHDGEGFHHHHHHHHFHHHHFHHHHHHGHGGHGGHHHFHGHHHHHFFHHHHHHBGHFFHGHGHHHHHGGEGGHHHHHGHHHHHHHHHGFGHHHHGHGHGHHCCGGGGGGGGGGAAGF?FFFFBFA@=BDDFF?-;FFF;@CFFEFEFFFFFFFFFBFDFFFFFFFFFFFFFFFFFFFFFF:FFFF/BF/FFFEFF?DECAFEFFFFFE:FFFFFFFB
+@M01368:8:000000000-A3GHV:1:1110:12808:18367/2:R1:AATTAACA:R2:GCCCACAC:F1:CACT:F2:GTTC
+CCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACAGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTCTT
++
+GGGGGGGGGHHHHHHHHHGGGGGGHHHHFHHGHHHHHHHHHHHHHGHHHGGHHHH3GFHEFHHHHHGHHGFHHHHHFGHHHHHGHGHGGHGGGGGGGHHHGGCGGGGHHGGGGGGGGGGGGGGGGGGGF-BAEFEBEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFFFFFFFAFEFDFFFFFFFFFF0BFBED=@DFFFFFFFFFEFFFFFBFAFB;0:;F0
+@M01368:8:000000000-A3GHV:1:1110:14751:26540/2:R1:TAACACTT:R2:ATGTTCGC:F1:GGGG:F2:CTGT
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGGTTGGGCTATTTGGGTTTTTTGACCCTGAAG
++
+GGGGGGGGGHHHHGGFHGGHGGCHHHHHHGHHHGHHGEGGGHHHHHHHHHHEFHHHHHHGEE?FGHGEHGGHHHGGGGGGEHHGGGGHHGGGEGHHHGHGGGDFGHHGHGGGGGCGAFFCCDFHHHH1CGGHBHFHFCGFFCDFHGCCE.CC:EGFHHCGHHGCF?FGGGFGGG;B9;FFFFFFEGEBF0;;;0;CFBFFF?D.DE.:..99-...;;//9A.;DE.9-./:FB.;//
+@M01368:8:000000000-A3GHV:1:1110:15519:10008/2:R1:CTGTAATA:R2:GGTTCCTA:F1:TTGA:F2:CTTC
+GGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAG
++
+GGGGGGGGGHHHGHHHFHHBGHHHGGGGHHHHHHGHHHHHHHHHHHHHHHGGHGGHHGHHHGGBGHHHHHHHHHHHHHHHHHGGFHHHGGGEGHHHHHHHHHHHHHHHGHHHHHHGHGHGHHGGGGGGDGGGGGGGGGBFFFFFFFFFFFFFFFFFFFECB-=BFFFFFFFFBB?E-A::FFBFFFFFBFFFFFFFFFFFFBFFEFFF;0BFF0:FE?FFFFBFFFFFFFFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1110:16559:7507/2:R1:CATTCAAT:R2:GCCCACAC:F1:TGTT:F2:GTTC
+CCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTAAT
++
+GGGGGGGGGHHHHHHHHHGGHGGHGHFHHHHFHHHHHHHHHHFHHGHHHHGHHHHHGGEEGHHHHHHHHHHHHHHHHHHHHHHGHGHGHHGGGGGGGHHGGGFGAGFGGGGGGGGGGGDDDFAGGFFFFCFAFEEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBFFFFFFFFFFFFFFE..@BFFBD./;:0FFFFF09B/AFCA=-99BFFBFFFFFFFB:BFBFFBFB9:
+@M01368:8:000000000-A3GHV:1:1110:16700:6843/2:R1:AAATAATA:R2:GTTCCTAC:F1:GGAT:F2:TTCA
+GGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTCTGTCTCTTATACACATTTGTCGCTC
++
+GGGGGGGGGHHGHHHGGHFHHHGGGGGHHHHHHHHHHGHHHHHHHHHHHGGHGGHHHHHHHGBGFFHHHHHHGHHHHHHHHGHHHHHGGGGGHHHHHHHHHHHHHHHFHHHHGHCG/GGHHGGGGGGAFGEEADAGGDFFFF00D>CFDDFFFB?AF?B;-@>.FEDFFFFF0BF-BDFFFFE00B0BF0FFFF:BFA0B0:BBFBBFFFFF0B0:000<00<BFBB0<00000<99.
+@M01368:8:000000000-A3GHV:1:1110:18014:7856/2:R1:ATAAATAA:R2:CATCACGA:F1:TAGG:F2:TGGA
+CACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTGTAGAGCTCGGGGGTCGCCGTGTATTTTTACAAAAAA
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHGGGGGHHHHHHHHHGHHHHHEGHHHHHEHGHGHHGGGCCGGHGHGCGGGGDHHHHFHGGGGGGGGGGGFGGFGAC-EFEGGGFFFGFF;DFFFBFFFFFFFFFFFFFFFFFFFEFFFBFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFB?DFF---;--D;9AFB0B:B0::00;0.;----.--.-9-:/00::090:0;..:
+@M01368:8:000000000-A3GHV:1:1110:23303:11846/2:R1:ACTTGGGG:R2:GTCCTACA:F1:GTAG:F2:AGCA
+TAATTAATTAACACACTTTAGTAAGTAAGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAA
++
+GGGGGGGGGHHHHHHGGHHHHHHHHGH5GHHHGGGGHHHHHFHHHHHHHEHHGFBGEEFE1FG5GFHHHHHFHHHGGGGGHHHHHHHHHHHGGHHHHHGGGGFHHFHH/EHHHGG?@EFHHHGGGGHFGGGGHHFHGGDGGGGFFFHGFDGGGCGACC;DFFB0CH0CCCFGBFBFB/:A?FFFE?AA.CFBECE0BBBF0F/A./9FFFFF./;/FFFFFFA.:////9BB/B/BB/
+@M01368:8:000000000-A3GHV:1:1111:13195:14562/2:R1:ATCAAAGA:R2:GTATCCGA:F1:CAGA:F2:CATC
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATCTGTCTCTTATACACATCTGACGCTGCCGACGG
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHDGHHHGGGGHHHHHHHHHHHHGHHHHHHHHHGGGGGHHGHHHHGFGFHHHHHHHHGHHHHHHHGHHHHHGGGGGHHHHGHHHHHHHHHHGFHHHHHGFGHGHHGGGGFCGFGFFFFAFFFFFFFFFFA;BADFFFAFFFFFFFFFEFFFEFFFFFFF;FDBFFFFFFFFFFFFFFFFF/BFF/BFFFEBFFFEFFFFFFFFF@B@-
+@M01368:8:000000000-A3GHV:1:1111:14287:20817/2:R1:GCCAACAC:R2:ATTCAATT:F1:GTTC:F2:GTTA
+TATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATGAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGTTAGACCTGTGATCC
++
+GGGGGGGGGHHHHHHHHHHHHHHHHHHHHHGHHHGHHHHGHHHGHGHFHHHGGGGHHHHHHHHBGGGFHHFGGHHGGHGHHHHHHHHEGFFHHFGGGGGHHEHHHBHHHHHFFHHGHGGGGGHFGF3FDGHHGCGGFGHHGGGG/2GG@E?GHHHGFEDGGC<FGHH?EGGG@DH.@ECEGGGGGGFGFFB0FGGGGGGEGGGFGEFEF0BE0AFFBFFFF9.-.00;000;;90;99
+@M01368:8:000000000-A3GHV:1:1111:23624:14516/2:R1:GTCCTACA:R2:CGACATCT:F1:AGCA:F2:GGTT
+CTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACCCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAA
++
+GGGGGGGGGHHCGHHHHHHHGHHHHHHHHHHHGDGEHHHHHHGHHHHHHHHHHHHHHHGGEFGHHHHHHHHBGFHHHHHHHHHHHHHHGHGGGGCEFGGCGHHHHFHHHHGHHHHFGHHHHHHGHGHGHHBCA?B-9FGFG?D;BD?9BFFFFFFF;DFFFF-.A;ADF-@=EF??A.BFFFEF>FDFFFFFFFFFFFBFFFFFFFFFFF/FFF/BFFFFFFFBA.?@;FFBDFFFF/
+@M01368:8:000000000-A3GHV:1:1111:7437:24508/2:R1:ACACACTT:R2:ACATCACG:F1:TAGT:F2:ATGG
+TCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTCTGTCTCTTATACACATCTGACGCTGCCGAGA
++
+GGGGGGGFGHHHHHHHHHHHHHGHHHGFHHHHGGGGDHHHHHHHHGFHHHHHGHHHHHHGHFHGHHGGGDFGDFFGGGFFGFFGHGHHHGGC?AD-:A-AFFGGG-?9EFEFGGFFBFEFCFFFFFFFBBBFFFFFFFFFFFFFFFBBFFFFFFFFFFFFFFFFFFEFFFFFFBFFFFEFEFFFF;CF-FFFFFFFF/BFFFFFFFFFFFFEFBFFFB/FFFFFFF//9A..;F--@9
+@M01368:8:000000000-A3GHV:1:1111:8665:25542/2:R1:TCCTACTT:R2:CTTTAGTA:F1:CAGG:F2:AGTA
+GTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGACAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTA
++
+GGGGGGGGGHHHHHHHFHHHHCHHGDGGGGHGGHHHHHHHHGHGHHHGGGGGHFHHHHFHHHFFHHHHHFGCGGEHFHHFGGHFHGGGGGGHHFEEEAFEFFDFHGHHHHGGGGGGGHH0DGGGGCGHCC-<CCBGHHHGEFFFFHH.C/<AEGHHEG.EEA0GE0:FB0CFGF:A?FFBF??FG0B;FGGGGFGE?BBF;BFBFFFF/F/B?DDF.;.;:ADD.BA/BBFFB:BFE/
+@M01368:8:000000000-A3GHV:1:1111:9655:13916/2:R1:GGCCCATA:R2:TTAGTAAG:F1:ACAC:F2:TATG
+TCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATTGCGTGGACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+GGGGGGGGGHHHHHGHHHHGHHGGHHGGHGGHHHGHHHHFHHGHHAFGGGHHHHHGHHHHFHFHHHHHECGGGHGHHHEFHFHGGGGGGGGFGFFGFFEFGEGHHHGHHGGDGGGHGFGGGGGGGGE@GCGGHHHGHHHHHGHHHHFHHGEGFFEGCE.ECCECEHCGGFFE/AABFFG0CFE0BFFF9CFGG.F/BBBFFGFGGGFFFFFFBFEDAEFFFFFBFFFFFFF0;FEBF:
+@M01368:8:000000000-A3GHV:1:1112:10272:7828/2:R1:GTATCCGA:R2:GTGCTCCG:F1:CATC:F2:GCTC
+AGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCAAGTGTAGTGCTCGGGGGGG
++
+GGGGGGGGGGGGGHHHHHHGGGGGGHHFHGGGGGFGHGGGGGGHHHHHHHHHHFHHHHFHGFFHHGF?ECEFFFFFFHHHHHH?FHHHHHHHHHGFHHHHHHGGGFGHHHHFHHHHHHHHHHGGGFGFGCGGGGHHHHHHHHHHHGGFFHGHHHHHFFHFCGFHCCGHGHCGGHG?DGGGGGFBBFGFBFBBBGGGB0000;CD?DFFAFF9=--;...://;////////.------
+@M01368:8:000000000-A3GHV:1:1112:9832:16531/2:R1:CTGTAATA:R2:GTATCCGA:F1:TTGA:F2:CATC
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGHFHHHHHHHHHHHHHHGHHHHGHFHHHGEEGGHHHGHHHHHHHHHHHHEHGHHGGGHGGHGHHHHHGHHHHGHHHHHHHHHHHHHHGHHHHHGEGCGHHHHHGHHHHHHHHHHHHHHGHFFGHGHHGGGDACDFFFFABFFFFFFFFFFD-BC?DA9.DFFBEA==B=?F.;ABBFBFEF-DAF/BFF9/FFFBB/9BFFFFFFF/BFBBFFFFFFF/9FEA?--B/;.
+@M01368:8:000000000-A3GHV:1:1112:9832:6701/2:R1:CGCCTGTA:R2:GCTAAAGT:F1:ATAT:F2:GAAC
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATT
++
+GGGGGGGGGFGHHHHHGHHHHHHHHHHHHCGHHHHHHHGHHHHHHDGHHGGAECHHGHHHHHHHGHHHGHGFHHHHGGHGGHHFHHHHHHFHHHHHHHHH2GHHHHGHGHHFHHGGFGGGHHGHHHHHFHHHHEFHHHHEFGFFHGEHCFGDFDFFFFFCFFFFFFFFFFFFFAFBFFDFFFFFFFFADCF?9?EFBFB9EF-A.;BFFFFFFFBFFFFFFFFFFFFBFFFFFFFFFF
+@M01368:8:000000000-A3GHV:1:1113:13532:8618/2:R1:GGAATCAA:R2:GCCCATAA:F1:AGAC:F2:CACT
+GGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTGGAT
++
+GGGGGGGGGHHHHHGGHHHGHHHGHHGGGGEHHGGHHHHHHHHHHHHHHGHHGHHHHHGGHHHHHFHHHHGCDCGHHHHHHHHEHHHGHGHHHGFHGGHGGHHHHHHHHFHHHFHHHGHHHHHHHHHFGGHHHHGGGEGAFHHGHHGGHHHHGHFBGFHGHGHGHGGHGGF@DAFEFBECAB=A.0BFFFEDF=A9.@D.-AAFFFA-:-..:.9/0:;0..-..0000::BFB09::
+@M01368:8:000000000-A3GHV:1:1113:21679:18011/2:R1:GATCACAG:R2:TTAGTAAG:F1:GTCT:F2:TATG
+TCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCTGTCTCTTATACACATCTGACGCTGCCGACGACCGAGCTAGTTGAGATC
++
+GGGGGGGGGHHHHHFHHHGHHHGFGHGGHGGHHHHHHGHHHHHHHGGGGFHHHHHHEGHHHHHHHHFGGFCGEHFHFGEGHHHFGGGGGHHHGGGEHGGGGGHHHHHHGDCCCGHHHHDGGGGCD/FCC-><FGFGEHEBDF0DGFFFFGGFFHCE.;.A;CF0;BFBFFGF/9C0;0CFGGF0F09FGGGFFFBBFEFFFB0FFEF0;09.:..9--::---;;-;;F00000:.00
+@M01368:8:000000000-A3GHV:1:1113:25528:14016/2:R1:CCTACAAG:R2:GTATCCGA:F1:CATT:F2:CATC
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGHGHHHHHHHHHGGGGHHHHHHHHHFHHHHHHHHHHHHGGGGGHHHHHHHGHHHHHHHHHHGGHHHHGHHGGHHHEGGGGGHHHHHHHHHGHHHHHGHHHHHGGHGHGHHGGGGGGGGGFEACFFFFFFFFFFFFFFFDFFFAFFFFBFAB@EFAAEFFFFF.ACF.BBFFEBFFFEB;FFFFFFFA/BFBFBBBFFFBFFFFFED.>DFFF.
+@M01368:8:000000000-A3GHV:1:1113:5741:16959/2:R1:TAGTAAGT:R2:GTATCCGA:F1:ATGT:F2:CATC
+GGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+GGGGGGGGGHHHHHHHGHHHHHHHHGHHHHGHDGHHHGGGGHHHHHHHHHHHHHHHGHHHHHGGGEGGHHHHFHHHHHHHHHHHHHHHHHHHHHHGHHGHHGGGGGHHHHHHHHHHHGHHHFHHHHHHGHGHGHGGGGCGGFGGFFFFFFFFFFFFFBFFFFFFFFFFFFFFAFFFFEAEFFFFFFFFFFF9BFFBFFFFFFFFFFFFFFBFFFFFFFFFFFFFFFFFFADAB-/BF.
+@M01368:8:000000000-A3GHV:1:1114:10130:11959/2:R1:CGTTCCCC:R2:ATCAGAGA:F1:TTAA:F2:CAGA
+ACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGCTGTCTCTTATACACATCTGACGCTGCCGACGAGCGATCTAGTGGAGAGTTCTGTGGGGCCGGGGATCCTTATAAAAAAAATAGA
++
+GGGGGGGGGGHHHHHGGHHHGGGCGGHGHGGGGHHGGGGHHHHHHGGGEGGHHHFGGGGG?E1FE?/EEHHHHHGHHGHHHHGHFHGHGHHGDGGFG2FF2?GHHHHHGCCCFHGHGHHHHGHHFEHHFGHHGHH<1=DGHHHGHHGHGAGAEEDG.CGCGHC0CGBFHGFBBF0ABDDEFF@?--:BB@.;:BF;0.0:0.0:000:BF.-.------.9/;000::0;0:--.000
+@M01368:8:000000000-A3GHV:1:1114:14540:5315/2:R1:CTTTAGTA:R2:CACTTGGG:F1:AGTA:F2:GGTA
+CTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCC
++
+GGGGGGGGGHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHHGHHHHHHHGHHHHFHFHHHGGGGGHHHHHHHHHHHHHGHHHHHHHHGGGGGGHHHFHHHGHHHHHHHHHHHHHHHHHHGHGHHHGGGFGHHHHHHHHFHHHHHF?1FHHGHGHGHGHHGGFFFFDBFBE;BCC.:BFFFFFFFFFFFFFF;AFFFFF-=-.AEDEFFFFF..9A;9FFFF0FFFFE00FFF0:BA.
+@M01368:8:000000000-A3GHV:1:1114:15066:16302/2:R1:TAAATAAG:R2:TTATTATT:F1:ACAT:F2:ATGT
+CTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGTGG
++
+GGGGGGGGGHHHHHHHHHHHHHHHDGHHHHFHHGHHGHHHHHGGGGEHHHHFHHFF5FHHFEGHHHGDHGGHGHGFGGGEHFGHHGGGGGHGHHHGHHFHHB3FGHHFGGGG?GFFHCCEBGFFECCDFEGFCFGCHHGFDDHHHGHHCFGGGGGFBFDGFG?-:..AFG.-C0C009;:00;00:9/:CEFFF?AE::9;9?0:FEF0;0..--./00::B/090000000;A....
+@M01368:8:000000000-A3GHV:1:1114:16639:15258/2:R1:CCTAAATA:R2:TTATTATT:F1:GCCC:F2:ATGT
+CTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCGCACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATG
++
+GGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHHHGHHHHHHGGGGGHGIHHHIH5DEGHHHF?FGHGGHGGHEGGHFHHGHGEHHGGGGGFFFGHFBG2GHEBGHHGHGGEG/GFGABEDFGHEED?GGHHFFGGGCFEGD/GFHFFGEFGCGG?CC??D-EF@EEEFGCDDBBFGGGEBBFFF09090A.BFGA.9CCA0;EBAB00BBFF.@-./;BB;BFFF0:00099AAFFF0
+@M01368:8:000000000-A3GHV:1:1114:2404:13066/2:R1:TCCTACAA:R2:ATGGATCA:F1:GCAT:F2:CAGG
+CTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGACCATACTTACTAAAGTGTGTTAATTAATTAATGCTTGTAGGACTGTCTCTTATACACATT
++
+GGGGGGGGGHHHHHHHHHFFHHHHGGGGGHFFFHHFHHHHHHHHHHHHHHHGFEGGGHGEDFCDFHGHFG@@DGGHHHHHHGGGGCGGGGGEHGGCGBB?CF99EGFGGFGG?D9CFFFF/BBFFFFFEF9BFFAFFFFEFFFFFFFFFFFFFFFFFFFFF.FFBBFFFFFFFFFFFF-9;;;BFFFFFB9BFBFBFABFFEFFFFFFFFFF::BFFBFFFF.9//;FFFFF/BFFB/
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_collection_example_pair1_results3.fastq.gz
Binary file test-data/paired_collection_example_pair1_results3.fastq.gz has changed
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_collection_example_pair2_results3.fastq.gz
Binary file test-data/paired_collection_example_pair2_results3.fastq.gz has changed
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_collection_example_results3.txt
--- a/test-data/paired_collection_example_results3.txt	Tue Jul 30 06:26:22 2019 -0400
+++ b/test-data/paired_collection_example_results3.txt	Fri Oct 08 09:57:12 2021 +0000
@@ -3,11 +3,13 @@
 ==========================
 Input filename: input_1.fastq
 Trimming mode: paired-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Using Nextera adapter for trimming (count: 29). Second best hit was Illumina (count: 0)
 Adapter sequence: 'CTGTCTCTTATA' (Nextera Transposase sequence; auto-detected)
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
@@ -16,10 +18,10 @@
 Length cut-off for read 2: 35 bp (default)
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_1.fastq
-Processing reads on 1 core in single-end mode ...
-Finished in 0.01 s (72 us/read; 0.83 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_1.fastq
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.01 s (115 µs/read; 0.52 M reads/minute).
 
 === Summary ===
 
@@ -33,10 +35,10 @@
 
 === Adapter 1 ===
 
-Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 52 times.
+Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 52 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-12 bp: 1
+1-9 bp: 0; 10-12 bp: 1
 
 Bases preceding removed adapters:
   A: 9.6%
@@ -85,11 +87,13 @@
 ==========================
 Input filename: input_2.fastq
 Trimming mode: paired-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Using Nextera adapter for trimming (count: 29). Second best hit was Illumina (count: 0)
 Adapter sequence: 'CTGTCTCTTATA' (Nextera Transposase sequence; auto-detected)
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
@@ -98,10 +102,10 @@
 Length cut-off for read 2: 35 bp (default)
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_2.fastq
-Processing reads on 1 core in single-end mode ...
-Finished in 0.01 s (55 us/read; 1.08 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_2.fastq
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.02 s (159 µs/read; 0.38 M reads/minute).
 
 === Summary ===
 
@@ -115,10 +119,10 @@
 
 === Adapter 1 ===
 
-Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 58 times.
+Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 58 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-12 bp: 1
+1-9 bp: 0; 10-12 bp: 1
 
 Bases preceding removed adapters:
   A: 12.1%
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_collection_example_results3gz.txt
--- a/test-data/paired_collection_example_results3gz.txt	Tue Jul 30 06:26:22 2019 -0400
+++ b/test-data/paired_collection_example_results3gz.txt	Fri Oct 08 09:57:12 2021 +0000
@@ -3,11 +3,13 @@
 ==========================
 Input filename: input_1.fastq.gz
 Trimming mode: paired-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Using Nextera adapter for trimming (count: 29). Second best hit was smallRNA (count: 0)
 Adapter sequence: 'CTGTCTCTTATA' (Nextera Transposase sequence; auto-detected)
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
@@ -17,10 +19,10 @@
 Output file will be GZIP compressed
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_1.fastq.gz
-Processing reads on 1 core in single-end mode ...
-Finished in 0.02 s (176 us/read; 0.34 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_1.fastq.gz
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.01 s (129 µs/read; 0.47 M reads/minute).
 
 === Summary ===
 
@@ -34,10 +36,10 @@
 
 === Adapter 1 ===
 
-Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 52 times.
+Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 52 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-12 bp: 1
+1-9 bp: 0; 10-12 bp: 1
 
 Bases preceding removed adapters:
   A: 9.6%
@@ -86,11 +88,13 @@
 ==========================
 Input filename: input_2.fastq.gz
 Trimming mode: paired-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Using Nextera adapter for trimming (count: 29). Second best hit was smallRNA (count: 0)
 Adapter sequence: 'CTGTCTCTTATA' (Nextera Transposase sequence; auto-detected)
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
@@ -100,10 +104,10 @@
 Output file will be GZIP compressed
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_2.fastq.gz
-Processing reads on 1 core in single-end mode ...
-Finished in 0.02 s (169 us/read; 0.36 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_2.fastq.gz
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.04 s (395 µs/read; 0.15 M reads/minute).
 
 === Summary ===
 
@@ -117,10 +121,10 @@
 
 === Adapter 1 ===
 
-Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 58 times.
+Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 58 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-12 bp: 1
+1-9 bp: 0; 10-12 bp: 1
 
 Bases preceding removed adapters:
   A: 12.1%
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_collection_example_unpair1_results3.fastq.gz
Binary file test-data/paired_collection_example_unpair1_results3.fastq.gz has changed
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_collection_example_unpair2_results3.fastq.gz
Binary file test-data/paired_collection_example_unpair2_results3.fastq.gz has changed
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_example_pair1_results2.fastq.gz
Binary file test-data/paired_example_pair1_results2.fastq.gz has changed
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_example_pair2_results2.fastq.gz
Binary file test-data/paired_example_pair2_results2.fastq.gz has changed
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_example_results2.txt
--- a/test-data/paired_example_results2.txt	Tue Jul 30 06:26:22 2019 -0400
+++ b/test-data/paired_example_results2.txt	Fri Oct 08 09:57:12 2021 +0000
@@ -3,21 +3,23 @@
 ==========================
 Input filename: input_1.fastq
 Trimming mode: paired-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Using Nextera adapter for trimming (count: 29). Second best hit was smallRNA (count: 0)
 Adapter sequence: 'CTGTCTCTTATA' (Nextera Transposase sequence; auto-detected)
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
 Minimum required sequence length for both reads before a sequence pair gets removed: 20 bp
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_1.fastq
-Processing reads on 1 core in single-end mode ...
-Finished in 0.01 s (75 us/read; 0.80 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_1.fastq
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.01 s (117 µs/read; 0.51 M reads/minute).
 
 === Summary ===
 
@@ -31,10 +33,10 @@
 
 === Adapter 1 ===
 
-Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 52 times.
+Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 52 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-12 bp: 1
+1-9 bp: 0; 10-12 bp: 1
 
 Bases preceding removed adapters:
   A: 9.6%
@@ -83,21 +85,23 @@
 ==========================
 Input filename: input_2.fastq
 Trimming mode: paired-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Using Nextera adapter for trimming (count: 29). Second best hit was smallRNA (count: 0)
 Adapter sequence: 'CTGTCTCTTATA' (Nextera Transposase sequence; auto-detected)
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
 Minimum required sequence length for both reads before a sequence pair gets removed: 20 bp
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_2.fastq
-Processing reads on 1 core in single-end mode ...
-Finished in 0.00 s (50 us/read; 1.19 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_2.fastq
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.03 s (256 µs/read; 0.23 M reads/minute).
 
 === Summary ===
 
@@ -111,10 +115,10 @@
 
 === Adapter 1 ===
 
-Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 58 times.
+Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 58 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-12 bp: 1
+1-9 bp: 0; 10-12 bp: 1
 
 Bases preceding removed adapters:
   A: 12.1%
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_example_results2gz.txt
--- a/test-data/paired_example_results2gz.txt	Tue Jul 30 06:26:22 2019 -0400
+++ b/test-data/paired_example_results2gz.txt	Fri Oct 08 09:57:12 2021 +0000
@@ -3,11 +3,13 @@
 ==========================
 Input filename: input_1.fastq.gz
 Trimming mode: paired-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Using Nextera adapter for trimming (count: 29). Second best hit was Illumina (count: 0)
 Adapter sequence: 'CTGTCTCTTATA' (Nextera Transposase sequence; auto-detected)
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
@@ -15,10 +17,10 @@
 Output file will be GZIP compressed
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_1.fastq.gz
-Processing reads on 1 core in single-end mode ...
-Finished in 0.03 s (287 us/read; 0.21 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_1.fastq.gz
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.01 s (114 µs/read; 0.53 M reads/minute).
 
 === Summary ===
 
@@ -32,10 +34,10 @@
 
 === Adapter 1 ===
 
-Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 52 times.
+Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 52 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-12 bp: 1
+1-9 bp: 0; 10-12 bp: 1
 
 Bases preceding removed adapters:
   A: 9.6%
@@ -84,11 +86,13 @@
 ==========================
 Input filename: input_2.fastq.gz
 Trimming mode: paired-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Using Nextera adapter for trimming (count: 29). Second best hit was Illumina (count: 0)
 Adapter sequence: 'CTGTCTCTTATA' (Nextera Transposase sequence; auto-detected)
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
@@ -96,10 +100,10 @@
 Output file will be GZIP compressed
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_2.fastq.gz
-Processing reads on 1 core in single-end mode ...
-Finished in 0.02 s (170 us/read; 0.35 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a CTGTCTCTTATA input_2.fastq.gz
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.02 s (232 µs/read; 0.26 M reads/minute).
 
 === Summary ===
 
@@ -113,10 +117,10 @@
 
 === Adapter 1 ===
 
-Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 58 times.
+Sequence: CTGTCTCTTATA; Type: regular 3'; Length: 12; Trimmed: 58 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-12 bp: 1
+1-9 bp: 0; 10-12 bp: 1
 
 Bases preceding removed adapters:
   A: 12.1%
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_hardtrimmed3_pair1_.fastqsanger
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/paired_hardtrimmed3_pair1_.fastqsanger	Fri Oct 08 09:57:12 2021 +0000
@@ -0,0 +1,396 @@
+@M01368:8:000000000-A3GHV:1:1101:6911:8255/1
+TCGCACCTACGTTCAATATT
++
+FFEFE;DFFFDFBFF/9BFB
+@M01368:8:000000000-A3GHV:1:1101:14518:9998/1
+GACCTGTGATCCATCGTGAT
++
+FF//;BFFFFFBF/9D:A//
+@M01368:8:000000000-A3GHV:1:1101:18422:19051/1
+TATTATTTATCGCACCTACG
++
+FFEFBFFFFFFFFFF:FFF.
+@M01368:8:000000000-A3GHV:1:1101:25545:21098/1
+TTTAAGGGGAACGGGTGGGG
++
+FBFFFFFFBF..A..;@B--
+@M01368:8:000000000-A3GHV:1:1101:5446:12248/1
+AAGGGGAACGTGTGGGCTAT
++
+FFFBFFFFFFEFFFFFEFFF
+@M01368:8:000000000-A3GHV:1:1101:5861:6452/1
+TGATCCATCGTGATGTCTTT
++
+FFFFFBFFBD.AFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1102:10403:6021/1
+ACCCTATGTCGCAGTATCTG
++
+..9..9/9;BEF;A:9/BFF
+@M01368:8:000000000-A3GHV:1:1102:10677:23253/1
+AATTCTGTCTCTTATACACA
++
+F0FFFFFFFFFFFFFFFFF:
+@M01368:8:000000000-A3GHV:1:1102:13809:1733/1
+GTCTCTTATACACATCTCCG
++
+FBBBFFFFFBFF0BFBF9F.
+@M01368:8:000000000-A3GHV:1:1102:17584:10050/1
+AATCTCGTATGCCGTCTTCT
++
+FF;.BF9ADF/9;A;DFFF0
+@M01368:8:000000000-A3GHV:1:1102:18842:24844/1
+TCTGTCTTTGATTCCTGCCT
++
+BBBFBFBFFF//BFB/BFF/
+@M01368:8:000000000-A3GHV:1:1102:21788:11027/1
+ACTAAAGTGTGTTAATTCTG
++
+FBFF0FFBBBBFBFBFFFF0
+@M01368:8:000000000-A3GHV:1:1102:5728:8777/1
+CCTGAAGTAGGAACCAGATG
++
+FFFFBBFFFFF/FFEFFFBB
+@M01368:8:000000000-A3GHV:1:1102:5983:21093/1
+TATTATTTATCGCACCTACG
++
+F0BFFFBBFF0EFFFFFFFA
+@M01368:8:000000000-A3GHV:1:1102:7765:18353/1
+CCTATGTCGCAGTATCTGTC
++
+.::FBFBFFE-A9:BFFFF0
+@M01368:8:000000000-A3GHV:1:1103:10405:17879/1
+TATTATTTATCGCACCTACG
++
+FBFFFFFFFFFFFFFFFFF?
+@M01368:8:000000000-A3GHV:1:1103:13493:8205/1
+GATTCCTGCCTCATCCTATT
++
+FFFFFFFFBFBBBFFFFEFF
+@M01368:8:000000000-A3GHV:1:1103:14060:21273/1
+TATTACTGTCTCTTATACAC
++
+:FFFBB/BFFFFFBFFFFB/
+@M01368:8:000000000-A3GHV:1:1103:14528:12993/1
+TCGCAGTATCTGTCTTTGAT
++
+BFEA-A.B//9F9F//;BBB
+@M01368:8:000000000-A3GHV:1:1103:17657:20856/1
+TGCCTCATCCTATTATTTAT
++
+FFFFFFFFFFF/FFFFBFF9
+@M01368:8:000000000-A3GHV:1:1103:23099:3794/1
+GCGAATCTCGGATGCCGTCT
++
+FFFF@;.9BF..;-./-A=F
+@M01368:8:000000000-A3GHV:1:1103:25465:20010/1
+AAAAAAAAAAAACAACAGAC
++
+.B/;:>---;--..;.../9
+@M01368:8:000000000-A3GHV:1:1103:25519:6301/1
+GAGACTAAGGCGAATTTCGT
++
+-B?DFFF/B/B?---.//;.
+@M01368:8:000000000-A3GHV:1:1103:6074:6549/1
+GTATCTGTCTTTGATTCCTG
++
+A./FFFFFFFFFFFF/BFF/
+@M01368:8:000000000-A3GHV:1:1104:11572:8264/1
+TATTATTTATCGCACCTACG
++
+B/BFFFF/BFFE?EFAFEF9
+@M01368:8:000000000-A3GHV:1:1104:11928:24197/1
+TAGGAACCAGATGTCGGATA
++
+FFFFFFFFFFFFFFFFF@D9
+@M01368:8:000000000-A3GHV:1:1104:12288:20635/1
+TCTGTCTTTGATTCCTGCCT
++
+;FBBFBFB///;99999BA9
+@M01368:8:000000000-A3GHV:1:1104:13832:4398/1
+ACCCAGTAGACTAGTGCGTC
++
+9...:.9//9////;/9-.-
+@M01368:8:000000000-A3GHV:1:1104:23670:4161/1
+GGGTGATAGACCTGTGATCC
++
+BF./AAF/BFFBBF/F/BFB
+@M01368:8:000000000-A3GHV:1:1104:24927:22253/1
+TTCCTGCCTCATCCTATTAT
++
+//;/;9/A/;/9BFFFBFBB
+@M01368:8:000000000-A3GHV:1:1104:4705:7727/1
+CGTGATGTCTTATTTAAGGG
++
+F?.AFFF/BFFEFFFFFEFF
+@M01368:8:000000000-A3GHV:1:1104:7756:4776/1
+GTCGCAGTATCTGTCTTTGA
++
+FFBEFFF:9FFFFBBFFFF/
+@M01368:8:000000000-A3GHV:1:1105:11310:21761/1
+TGTCGGATACAGTTCACTTT
++
+FFBFFFFFFFFFFFFEFFF0
+@M01368:8:000000000-A3GHV:1:1105:11578:14676/1
+TGAAGTAGGAACCAGATGTC
++
+FF/FFFFFFFFFFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1105:13575:19255/1
+TGGGCTATTTAGGTTTTATG
++
+FF?B---;B99//9/;A//9
+@M01368:8:000000000-A3GHV:1:1105:15502:11453/1
+CTGTCTCTTATACACATCTC
++
+FFFFEFFFFFFFFBFFFBFF
+@M01368:8:000000000-A3GHV:1:1105:16787:9771/1
+GACCTGTGATCCATCGTGAT
++
+FFFFFFBFFFFFFFFFEFF/
+@M01368:8:000000000-A3GHV:1:1105:17564:15723/1
+TTAGGTTTTATGACCCTGAA
++
+FFBBFBBFFFFFE1:BFFB0
+@M01368:8:000000000-A3GHV:1:1105:18108:12091/1
+GATACCTGTCTCTTATACAC
++
+F-A.B//;BFFEF//BB///
+@M01368:8:000000000-A3GHV:1:1105:18331:16683/1
+CGCACCTACGTTCAATATTA
++
+B.DABFFFFFFB.//:FB//
+@M01368:8:000000000-A3GHV:1:1105:20577:18421/1
+CTTTGATTCCTGCCTCATCC
++
+FBB/:FF9BF/BF.BBFF/:
+@M01368:8:000000000-A3GHV:1:1105:21099:2895/1
+ATTCCTGCCTCATCCTATTT
++
+BFBFFBFF.0:000BFFBF0
+@M01368:8:000000000-A3GHV:1:1105:26469:19245/1
+ACCTGTGATCCATCGTGATG
++
+FFFFFFF/9FFFFBDEFFFF
+@M01368:8:000000000-A3GHV:1:1105:7169:17145/1
+GAACATACTTACTAAAGTGT
++
+-9@DDBFFFFFFFFBBFFF0
+@M01368:8:000000000-A3GHV:1:1106:15481:16176/1
+TGTGGGCTATTTAGGTTTTT
++
+FE:AAFEF.BFFFFF;9FF.
+@M01368:8:000000000-A3GHV:1:1106:17389:18671/1
+GCAGTATCTGGCTTTGATTC
++
+..;A;/B/;B//;;//BBF/
+@M01368:8:000000000-A3GHV:1:1106:22927:3863/1
+CTCCGAGCCCACGAGACTAA
++
+//FFF-=--.99=--.9///
+@M01368:8:000000000-A3GHV:1:1106:23625:4236/1
+ATTCCTGCCTCATCCTATTA
++
+EFFFFFFFAF///9FF/BB/
+@M01368:8:000000000-A3GHV:1:1106:26031:14826/1
+GTATGCCGTCTTCTGCTTGA
++
+AFFFFFF;;BFE/BFFFFB:
+@M01368:8:000000000-A3GHV:1:1106:27607:15990/1
+AACTACAACCCACGGACGCA
++
+;B.//////;...---9---
+@M01368:8:000000000-A3GHV:1:1106:6455:17124/1
+TATTATTTATCGCACCTACG
++
+F/FFBFFFFFFADE>BFFF9
+@M01368:8:000000000-A3GHV:1:1107:14451:26748/1
+TTTAGGTTTTATGACCCTGA
++
+FBFFFF;FFEBFBFFB./9.
+@M01368:8:000000000-A3GHV:1:1107:18714:24788/1
+TTTAGGTTTTATGACCCTGA
++
+FFFFFFBFFFFFBBFFBBF/
+@M01368:8:000000000-A3GHV:1:1107:21355:8333/1
+CCTGAAGTAGGAACCAGATG
++
+FFFFFFFFFFFFBFF.AA/9
+@M01368:8:000000000-A3GHV:1:1107:22864:15712/1
+ACTAAGGCGAATCTCGTATG
++
+9DFFF/FFBF;-.:;.9A//
+@M01368:8:000000000-A3GHV:1:1107:24817:14233/1
+TCAATATTACAGGCGAACAT
++
+FFFFFBF//:BFBACF--9/
+@M01368:8:000000000-A3GHV:1:1107:24830:14440/1
+ATCCTATTATTTATCGCACC
++
+FFFFFFFFFFF/BFBEFFC-
+@M01368:8:000000000-A3GHV:1:1107:26478:23602/1
+CTGTCTCTTATACACCTCTC
++
+BFFFBBFFF//B/////-;9
+@M01368:8:000000000-A3GHV:1:1108:11059:23181/1
+GACCTGTGATCCATCGTGAT
++
+FFFFBF;BBFFBFFFFE?F/
+@M01368:8:000000000-A3GHV:1:1108:12233:13498/1
+GAACCCTGTCTCTTATACAC
++
+EFF?EFFFF0BFFFFBBB00
+@M01368:8:000000000-A3GHV:1:1108:14328:14751/1
+GGATACCTGTCTCTTATACA
++
+EFFFBF/BF/FFEFFBFFF/
+@M01368:8:000000000-A3GHV:1:1108:16350:22621/1
+TGGGCTATTTAGGTTTTATG
++
+BE.99FAFFFFFFF/;EFF/
+@M01368:8:000000000-A3GHV:1:1108:21791:23272/1
+TGTGGGCTATTTAGGTTTTA
++
+EEFEFFFBFBFBBFFFFF./
+@M01368:8:000000000-A3GHV:1:1108:23314:26089/1
+TGAAGTAGGAACCAGATGTG
++
+BB./:BFFF/F;AA?F////
+@M01368:8:000000000-A3GHV:1:1108:25084:18127/1
+TGTGATCCATCGTGATGTCT
++
+FF9FBFFB/F/.;FFFF/BB
+@M01368:8:000000000-A3GHV:1:1108:7626:10048/1
+TATGCCGTCTTCTGCTTGAA
++
+AAFFFFFFAFABBFFFB/;;
+@M01368:8:000000000-A3GHV:1:1109:11270:12255/1
+AGACTAAGGCGAATCTCGTT
++
+-@DBFFFFBFD---.;BAA.
+@M01368:8:000000000-A3GHV:1:1109:19224:11655/1
+CTTATACACATCTCCGAGCC
++
+FFB/;F/99/FBFFBDCF;B
+@M01368:8:000000000-A3GHV:1:1109:21978:9490/1
+GGCGAATCTCGTATGCAGTT
++
+FFFFA;;;FF..9//;/;;/
+@M01368:8:000000000-A3GHV:1:1109:22910:4079/1
+GATACAGTCCACTTTAGCTA
++
+CCDFFFFFFF0BFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1109:24217:19077/1
+TGCCTCATCCTATTACTGTC
++
+9;F./B//BBFB9////99/
+@M01368:8:000000000-A3GHV:1:1109:25237:11722/1
+AGGCGAATATCGTATGCCGT
++
+BF/99D-;.//.../9;B-.
+@M01368:8:000000000-A3GHV:1:1109:27103:7153/1
+GACCCTGAAGTAGCTGTCTC
++
+BBFFBFFFF///;/9B;///
+@M01368:8:000000000-A3GHV:1:1109:8763:7859/1
+GGGCTATTTAGGCTTTATGC
++
+EDAA.A/BFFFFFFFFFEB/
+@M01368:8:000000000-A3GHV:1:1110:12808:18367/1
+AAGGGGAACGTGTGGGCCTG
++
+BFBFFB9..AF?FFFFFFF9
+@M01368:8:000000000-A3GHV:1:1110:14751:26540/1
+GTATCTGTCTTTGATTCCTG
++
+9-/;B9BF/9BB//B/;///
+@M01368:8:000000000-A3GHV:1:1110:15519:10008/1
+ATGACCCTGAAGTAGGAACC
++
+FFFFFBFFF.BFFFBFBBA;
+@M01368:8:000000000-A3GHV:1:1110:16559:7507/1
+AGGGTGATAGACCTGTGATC
++
+/99;;:.//:FFFFBBF//9
+@M01368:8:000000000-A3GHV:1:1110:16700:6843/1
+CTTATACACATCTCCGAGCC
++
+BFFFFB/BFFBFFF/ADCAD
+@M01368:8:000000000-A3GHV:1:1110:18014:7856/1
+TGCTTGCAAAAAAAAAATAG
++
+/BBFFF.9/FF?DA=@9./9
+@M01368:8:000000000-A3GHV:1:1110:23303:11846/1
+CTGTCTTTGATTCCTGCCTC
++
+FBBFFFF/BBFFFFBFF9B;
+@M01368:8:000000000-A3GHV:1:1111:13195:14562/1
+ACATCTCCGAGCCCACGAGA
++
+FFEFFFFED-DCFF?.:BFA
+@M01368:8:000000000-A3GHV:1:1111:14287:20817/1
+ATTAAAGTGTGTTAATTAAT
++
+B//B/;/;9//9//;B/:B9
+@M01368:8:000000000-A3GHV:1:1111:23624:14516/1
+CATCGTGATGTCTTATTTAG
++
+B/FBDE9/;99/B/BFFEF/
+@M01368:8:000000000-A3GHV:1:1111:7437:24508/1
+CACATCTCCGAGCCCACGAG
++
+FFFFB:FFFFD=CAEEEF>-
+@M01368:8:000000000-A3GHV:1:1111:8665:25542/1
+TACGTTCAATATTACAGGCG
++
+FFFBA/F//BFFFBF/;/A-
+@M01368:8:000000000-A3GHV:1:1111:9655:13916/1
+GTCGCAGTATCTGTCTTTGA
++
+F/B?A@F-9BBFF//BB/9/
+@M01368:8:000000000-A3GHV:1:1112:10272:7828/1
+CGAATCTCGTATGCCGTCTT
++
+FAD--.99;A?////:.9A.
+@M01368:8:000000000-A3GHV:1:1112:9832:16531/1
+ATGACCTTGAAGTAGGAACC
++
+FFF/BF//9/B//9:B//..
+@M01368:8:000000000-A3GHV:1:1112:9832:6701/1
+TTTATGACCCTGAAGTAGGA
++
+FFFFFFF/B./FB///;BF/
+@M01368:8:000000000-A3GHV:1:1113:13532:8618/1
+AGCTACCTCCAAGTGTTATG
++
+FF/BFFB/:.BB//;FBFFF
+@M01368:8:000000000-A3GHV:1:1113:21679:18011/1
+AGACTAAGGCGAAGTTCATT
++
+;-;AFFE;/99-9--/;///
+@M01368:8:000000000-A3GHV:1:1113:25528:14016/1
+TCGTGATGTCTTATTTAAGG
++
+FFFEABF//99FFEFFFBFF
+@M01368:8:000000000-A3GHV:1:1113:5741:16959/1
+GGGCTATTTAGGTTTTATGA
++
+9AD;.FFFB/B/;FBA/B//
+@M01368:8:000000000-A3GHV:1:1114:10130:11959/1
+GCAACAAACACACATCCAGA
++
+F./B/..9.9:...//////
+@M01368:8:000000000-A3GHV:1:1114:14540:5315/1
+TGGGGGCTATTTAGGTTTTT
++
+;A.-=A--:BBFB90;;FE.
+@M01368:8:000000000-A3GHV:1:1114:15066:16302/1
+TAATTATTGCTTGTAGGACA
++
+F/;BFF/;/////9/////.
+@M01368:8:000000000-A3GHV:1:1114:16639:15258/1
+ACATACTTACTAAATTGTGT
++
+-9-99/B9F/://///99/;
+@M01368:8:000000000-A3GHV:1:1114:2404:13066/1
+ATCTGTCTATTATACACATC
++
+FFFFFFFFFFFFFFFFEFF0
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_hardtrimmed3_pair2_.fastqsanger
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/paired_hardtrimmed3_pair2_.fastqsanger	Fri Oct 08 09:57:12 2021 +0000
@@ -0,0 +1,396 @@
+@M01368:8:000000000-A3GHV:1:1101:6911:8255/1
+TCGCACCTACGTTCAATATT
++
+FFEFE;DFFFDFBFF/9BFB
+@M01368:8:000000000-A3GHV:1:1101:14518:9998/1
+GACCTGTGATCCATCGTGAT
++
+FF//;BFFFFFBF/9D:A//
+@M01368:8:000000000-A3GHV:1:1101:18422:19051/1
+TATTATTTATCGCACCTACG
++
+FFEFBFFFFFFFFFF:FFF.
+@M01368:8:000000000-A3GHV:1:1101:25545:21098/1
+TTTAAGGGGAACGGGTGGGG
++
+FBFFFFFFBF..A..;@B--
+@M01368:8:000000000-A3GHV:1:1101:5446:12248/1
+AAGGGGAACGTGTGGGCTAT
++
+FFFBFFFFFFEFFFFFEFFF
+@M01368:8:000000000-A3GHV:1:1101:5861:6452/1
+TGATCCATCGTGATGTCTTT
++
+FFFFFBFFBD.AFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1102:10403:6021/1
+ACCCTATGTCGCAGTATCTG
++
+..9..9/9;BEF;A:9/BFF
+@M01368:8:000000000-A3GHV:1:1102:10677:23253/1
+AATTCTGTCTCTTATACACA
++
+F0FFFFFFFFFFFFFFFFF:
+@M01368:8:000000000-A3GHV:1:1102:13809:1733/1
+GTCTCTTATACACATCTCCG
++
+FBBBFFFFFBFF0BFBF9F.
+@M01368:8:000000000-A3GHV:1:1102:17584:10050/1
+AATCTCGTATGCCGTCTTCT
++
+FF;.BF9ADF/9;A;DFFF0
+@M01368:8:000000000-A3GHV:1:1102:18842:24844/1
+TCTGTCTTTGATTCCTGCCT
++
+BBBFBFBFFF//BFB/BFF/
+@M01368:8:000000000-A3GHV:1:1102:21788:11027/1
+ACTAAAGTGTGTTAATTCTG
++
+FBFF0FFBBBBFBFBFFFF0
+@M01368:8:000000000-A3GHV:1:1102:5728:8777/1
+CCTGAAGTAGGAACCAGATG
++
+FFFFBBFFFFF/FFEFFFBB
+@M01368:8:000000000-A3GHV:1:1102:5983:21093/1
+TATTATTTATCGCACCTACG
++
+F0BFFFBBFF0EFFFFFFFA
+@M01368:8:000000000-A3GHV:1:1102:7765:18353/1
+CCTATGTCGCAGTATCTGTC
++
+.::FBFBFFE-A9:BFFFF0
+@M01368:8:000000000-A3GHV:1:1103:10405:17879/1
+TATTATTTATCGCACCTACG
++
+FBFFFFFFFFFFFFFFFFF?
+@M01368:8:000000000-A3GHV:1:1103:13493:8205/1
+GATTCCTGCCTCATCCTATT
++
+FFFFFFFFBFBBBFFFFEFF
+@M01368:8:000000000-A3GHV:1:1103:14060:21273/1
+TATTACTGTCTCTTATACAC
++
+:FFFBB/BFFFFFBFFFFB/
+@M01368:8:000000000-A3GHV:1:1103:14528:12993/1
+TCGCAGTATCTGTCTTTGAT
++
+BFEA-A.B//9F9F//;BBB
+@M01368:8:000000000-A3GHV:1:1103:17657:20856/1
+TGCCTCATCCTATTATTTAT
++
+FFFFFFFFFFF/FFFFBFF9
+@M01368:8:000000000-A3GHV:1:1103:23099:3794/1
+GCGAATCTCGGATGCCGTCT
++
+FFFF@;.9BF..;-./-A=F
+@M01368:8:000000000-A3GHV:1:1103:25465:20010/1
+AAAAAAAAAAAACAACAGAC
++
+.B/;:>---;--..;.../9
+@M01368:8:000000000-A3GHV:1:1103:25519:6301/1
+GAGACTAAGGCGAATTTCGT
++
+-B?DFFF/B/B?---.//;.
+@M01368:8:000000000-A3GHV:1:1103:6074:6549/1
+GTATCTGTCTTTGATTCCTG
++
+A./FFFFFFFFFFFF/BFF/
+@M01368:8:000000000-A3GHV:1:1104:11572:8264/1
+TATTATTTATCGCACCTACG
++
+B/BFFFF/BFFE?EFAFEF9
+@M01368:8:000000000-A3GHV:1:1104:11928:24197/1
+TAGGAACCAGATGTCGGATA
++
+FFFFFFFFFFFFFFFFF@D9
+@M01368:8:000000000-A3GHV:1:1104:12288:20635/1
+TCTGTCTTTGATTCCTGCCT
++
+;FBBFBFB///;99999BA9
+@M01368:8:000000000-A3GHV:1:1104:13832:4398/1
+ACCCAGTAGACTAGTGCGTC
++
+9...:.9//9////;/9-.-
+@M01368:8:000000000-A3GHV:1:1104:23670:4161/1
+GGGTGATAGACCTGTGATCC
++
+BF./AAF/BFFBBF/F/BFB
+@M01368:8:000000000-A3GHV:1:1104:24927:22253/1
+TTCCTGCCTCATCCTATTAT
++
+//;/;9/A/;/9BFFFBFBB
+@M01368:8:000000000-A3GHV:1:1104:4705:7727/1
+CGTGATGTCTTATTTAAGGG
++
+F?.AFFF/BFFEFFFFFEFF
+@M01368:8:000000000-A3GHV:1:1104:7756:4776/1
+GTCGCAGTATCTGTCTTTGA
++
+FFBEFFF:9FFFFBBFFFF/
+@M01368:8:000000000-A3GHV:1:1105:11310:21761/1
+TGTCGGATACAGTTCACTTT
++
+FFBFFFFFFFFFFFFEFFF0
+@M01368:8:000000000-A3GHV:1:1105:11578:14676/1
+TGAAGTAGGAACCAGATGTC
++
+FF/FFFFFFFFFFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1105:13575:19255/1
+TGGGCTATTTAGGTTTTATG
++
+FF?B---;B99//9/;A//9
+@M01368:8:000000000-A3GHV:1:1105:15502:11453/1
+CTGTCTCTTATACACATCTC
++
+FFFFEFFFFFFFFBFFFBFF
+@M01368:8:000000000-A3GHV:1:1105:16787:9771/1
+GACCTGTGATCCATCGTGAT
++
+FFFFFFBFFFFFFFFFEFF/
+@M01368:8:000000000-A3GHV:1:1105:17564:15723/1
+TTAGGTTTTATGACCCTGAA
++
+FFBBFBBFFFFFE1:BFFB0
+@M01368:8:000000000-A3GHV:1:1105:18108:12091/1
+GATACCTGTCTCTTATACAC
++
+F-A.B//;BFFEF//BB///
+@M01368:8:000000000-A3GHV:1:1105:18331:16683/1
+CGCACCTACGTTCAATATTA
++
+B.DABFFFFFFB.//:FB//
+@M01368:8:000000000-A3GHV:1:1105:20577:18421/1
+CTTTGATTCCTGCCTCATCC
++
+FBB/:FF9BF/BF.BBFF/:
+@M01368:8:000000000-A3GHV:1:1105:21099:2895/1
+ATTCCTGCCTCATCCTATTT
++
+BFBFFBFF.0:000BFFBF0
+@M01368:8:000000000-A3GHV:1:1105:26469:19245/1
+ACCTGTGATCCATCGTGATG
++
+FFFFFFF/9FFFFBDEFFFF
+@M01368:8:000000000-A3GHV:1:1105:7169:17145/1
+GAACATACTTACTAAAGTGT
++
+-9@DDBFFFFFFFFBBFFF0
+@M01368:8:000000000-A3GHV:1:1106:15481:16176/1
+TGTGGGCTATTTAGGTTTTT
++
+FE:AAFEF.BFFFFF;9FF.
+@M01368:8:000000000-A3GHV:1:1106:17389:18671/1
+GCAGTATCTGGCTTTGATTC
++
+..;A;/B/;B//;;//BBF/
+@M01368:8:000000000-A3GHV:1:1106:22927:3863/1
+CTCCGAGCCCACGAGACTAA
++
+//FFF-=--.99=--.9///
+@M01368:8:000000000-A3GHV:1:1106:23625:4236/1
+ATTCCTGCCTCATCCTATTA
++
+EFFFFFFFAF///9FF/BB/
+@M01368:8:000000000-A3GHV:1:1106:26031:14826/1
+GTATGCCGTCTTCTGCTTGA
++
+AFFFFFF;;BFE/BFFFFB:
+@M01368:8:000000000-A3GHV:1:1106:27607:15990/1
+AACTACAACCCACGGACGCA
++
+;B.//////;...---9---
+@M01368:8:000000000-A3GHV:1:1106:6455:17124/1
+TATTATTTATCGCACCTACG
++
+F/FFBFFFFFFADE>BFFF9
+@M01368:8:000000000-A3GHV:1:1107:14451:26748/1
+TTTAGGTTTTATGACCCTGA
++
+FBFFFF;FFEBFBFFB./9.
+@M01368:8:000000000-A3GHV:1:1107:18714:24788/1
+TTTAGGTTTTATGACCCTGA
++
+FFFFFFBFFFFFBBFFBBF/
+@M01368:8:000000000-A3GHV:1:1107:21355:8333/1
+CCTGAAGTAGGAACCAGATG
++
+FFFFFFFFFFFFBFF.AA/9
+@M01368:8:000000000-A3GHV:1:1107:22864:15712/1
+ACTAAGGCGAATCTCGTATG
++
+9DFFF/FFBF;-.:;.9A//
+@M01368:8:000000000-A3GHV:1:1107:24817:14233/1
+TCAATATTACAGGCGAACAT
++
+FFFFFBF//:BFBACF--9/
+@M01368:8:000000000-A3GHV:1:1107:24830:14440/1
+ATCCTATTATTTATCGCACC
++
+FFFFFFFFFFF/BFBEFFC-
+@M01368:8:000000000-A3GHV:1:1107:26478:23602/1
+CTGTCTCTTATACACCTCTC
++
+BFFFBBFFF//B/////-;9
+@M01368:8:000000000-A3GHV:1:1108:11059:23181/1
+GACCTGTGATCCATCGTGAT
++
+FFFFBF;BBFFBFFFFE?F/
+@M01368:8:000000000-A3GHV:1:1108:12233:13498/1
+GAACCCTGTCTCTTATACAC
++
+EFF?EFFFF0BFFFFBBB00
+@M01368:8:000000000-A3GHV:1:1108:14328:14751/1
+GGATACCTGTCTCTTATACA
++
+EFFFBF/BF/FFEFFBFFF/
+@M01368:8:000000000-A3GHV:1:1108:16350:22621/1
+TGGGCTATTTAGGTTTTATG
++
+BE.99FAFFFFFFF/;EFF/
+@M01368:8:000000000-A3GHV:1:1108:21791:23272/1
+TGTGGGCTATTTAGGTTTTA
++
+EEFEFFFBFBFBBFFFFF./
+@M01368:8:000000000-A3GHV:1:1108:23314:26089/1
+TGAAGTAGGAACCAGATGTG
++
+BB./:BFFF/F;AA?F////
+@M01368:8:000000000-A3GHV:1:1108:25084:18127/1
+TGTGATCCATCGTGATGTCT
++
+FF9FBFFB/F/.;FFFF/BB
+@M01368:8:000000000-A3GHV:1:1108:7626:10048/1
+TATGCCGTCTTCTGCTTGAA
++
+AAFFFFFFAFABBFFFB/;;
+@M01368:8:000000000-A3GHV:1:1109:11270:12255/1
+AGACTAAGGCGAATCTCGTT
++
+-@DBFFFFBFD---.;BAA.
+@M01368:8:000000000-A3GHV:1:1109:19224:11655/1
+CTTATACACATCTCCGAGCC
++
+FFB/;F/99/FBFFBDCF;B
+@M01368:8:000000000-A3GHV:1:1109:21978:9490/1
+GGCGAATCTCGTATGCAGTT
++
+FFFFA;;;FF..9//;/;;/
+@M01368:8:000000000-A3GHV:1:1109:22910:4079/1
+GATACAGTCCACTTTAGCTA
++
+CCDFFFFFFF0BFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1109:24217:19077/1
+TGCCTCATCCTATTACTGTC
++
+9;F./B//BBFB9////99/
+@M01368:8:000000000-A3GHV:1:1109:25237:11722/1
+AGGCGAATATCGTATGCCGT
++
+BF/99D-;.//.../9;B-.
+@M01368:8:000000000-A3GHV:1:1109:27103:7153/1
+GACCCTGAAGTAGCTGTCTC
++
+BBFFBFFFF///;/9B;///
+@M01368:8:000000000-A3GHV:1:1109:8763:7859/1
+GGGCTATTTAGGCTTTATGC
++
+EDAA.A/BFFFFFFFFFEB/
+@M01368:8:000000000-A3GHV:1:1110:12808:18367/1
+AAGGGGAACGTGTGGGCCTG
++
+BFBFFB9..AF?FFFFFFF9
+@M01368:8:000000000-A3GHV:1:1110:14751:26540/1
+GTATCTGTCTTTGATTCCTG
++
+9-/;B9BF/9BB//B/;///
+@M01368:8:000000000-A3GHV:1:1110:15519:10008/1
+ATGACCCTGAAGTAGGAACC
++
+FFFFFBFFF.BFFFBFBBA;
+@M01368:8:000000000-A3GHV:1:1110:16559:7507/1
+AGGGTGATAGACCTGTGATC
++
+/99;;:.//:FFFFBBF//9
+@M01368:8:000000000-A3GHV:1:1110:16700:6843/1
+CTTATACACATCTCCGAGCC
++
+BFFFFB/BFFBFFF/ADCAD
+@M01368:8:000000000-A3GHV:1:1110:18014:7856/1
+TGCTTGCAAAAAAAAAATAG
++
+/BBFFF.9/FF?DA=@9./9
+@M01368:8:000000000-A3GHV:1:1110:23303:11846/1
+CTGTCTTTGATTCCTGCCTC
++
+FBBFFFF/BBFFFFBFF9B;
+@M01368:8:000000000-A3GHV:1:1111:13195:14562/1
+ACATCTCCGAGCCCACGAGA
++
+FFEFFFFED-DCFF?.:BFA
+@M01368:8:000000000-A3GHV:1:1111:14287:20817/1
+ATTAAAGTGTGTTAATTAAT
++
+B//B/;/;9//9//;B/:B9
+@M01368:8:000000000-A3GHV:1:1111:23624:14516/1
+CATCGTGATGTCTTATTTAG
++
+B/FBDE9/;99/B/BFFEF/
+@M01368:8:000000000-A3GHV:1:1111:7437:24508/1
+CACATCTCCGAGCCCACGAG
++
+FFFFB:FFFFD=CAEEEF>-
+@M01368:8:000000000-A3GHV:1:1111:8665:25542/1
+TACGTTCAATATTACAGGCG
++
+FFFBA/F//BFFFBF/;/A-
+@M01368:8:000000000-A3GHV:1:1111:9655:13916/1
+GTCGCAGTATCTGTCTTTGA
++
+F/B?A@F-9BBFF//BB/9/
+@M01368:8:000000000-A3GHV:1:1112:10272:7828/1
+CGAATCTCGTATGCCGTCTT
++
+FAD--.99;A?////:.9A.
+@M01368:8:000000000-A3GHV:1:1112:9832:16531/1
+ATGACCTTGAAGTAGGAACC
++
+FFF/BF//9/B//9:B//..
+@M01368:8:000000000-A3GHV:1:1112:9832:6701/1
+TTTATGACCCTGAAGTAGGA
++
+FFFFFFF/B./FB///;BF/
+@M01368:8:000000000-A3GHV:1:1113:13532:8618/1
+AGCTACCTCCAAGTGTTATG
++
+FF/BFFB/:.BB//;FBFFF
+@M01368:8:000000000-A3GHV:1:1113:21679:18011/1
+AGACTAAGGCGAAGTTCATT
++
+;-;AFFE;/99-9--/;///
+@M01368:8:000000000-A3GHV:1:1113:25528:14016/1
+TCGTGATGTCTTATTTAAGG
++
+FFFEABF//99FFEFFFBFF
+@M01368:8:000000000-A3GHV:1:1113:5741:16959/1
+GGGCTATTTAGGTTTTATGA
++
+9AD;.FFFB/B/;FBA/B//
+@M01368:8:000000000-A3GHV:1:1114:10130:11959/1
+GCAACAAACACACATCCAGA
++
+F./B/..9.9:...//////
+@M01368:8:000000000-A3GHV:1:1114:14540:5315/1
+TGGGGGCTATTTAGGTTTTT
++
+;A.-=A--:BBFB90;;FE.
+@M01368:8:000000000-A3GHV:1:1114:15066:16302/1
+TAATTATTGCTTGTAGGACA
++
+F/;BFF/;/////9/////.
+@M01368:8:000000000-A3GHV:1:1114:16639:15258/1
+ACATACTTACTAAATTGTGT
++
+-9-99/B9F/://///99/;
+@M01368:8:000000000-A3GHV:1:1114:2404:13066/1
+ATCTGTCTATTATACACATC
++
+FFFFFFFFFFFFFFFFEFF0
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_hardtrimmed5_pair1_.fastqsanger
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/paired_hardtrimmed5_pair1_.fastqsanger	Fri Oct 08 09:57:12 2021 +0000
@@ -0,0 +1,396 @@
+@M01368:8:000000000-A3GHV:1:1101:6911:8255/1
+ATCTGGTTCCTACTTCAGGG
++
+BCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1101:14518:9998/1
+GTTATTATTATGTCCTACAA
++
+AAAAAFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1101:18422:19051/1
+GTATCCGACATCTGGTTCCT
++
+CCCCCFDDDDDFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1101:25545:21098/1
+ATTAATTAACACACTTTAGT
++
+33AA?DFD5BDFGGGFEBDG
+@M01368:8:000000000-A3GHV:1:1101:5446:12248/1
+AATTAACACACTTTAGTAAG
++
+CCCCDFFFFCCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1101:5861:6452/1
+ATTATGTCCTACAAGCATTA
++
+ABCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:10403:6021/1
+CGCTCCGGGCCCATAACACT
++
+>A@AAAAD2ADDFFGGGGGF
+@M01368:8:000000000-A3GHV:1:1102:10677:23253/1
+CCTTAAATAAGACATCACGA
++
+ABBBBFFFFFFFGGGGGGGC
+@M01368:8:000000000-A3GHV:1:1102:13809:1733/1
+ATATTGAACGTAGGTGCGAT
++
+BCCBCFFFFFBFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:17584:10050/1
+ATCAAAGACAGATACTGCGA
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:18842:24844/1
+CACTTGGGGGTAGCTAAAGT
++
+BBBCBFF@CCBBGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:21788:11027/1
+GCCCACACGTTCCCCTTAAA
++
+ABCCBCCBBFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:5728:8777/1
+ATATTGAACGTAGGTGCGAT
++
+BBBBBFFFFFAFGG5GGGGG
+@M01368:8:000000000-A3GHV:1:1102:5983:21093/1
+GTATCCGACATCTGGTTCCT
++
+AAABCFCABBCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:7765:18353/1
+CTCCGGGCCCATAACACTTG
++
+CCDCCCCCCBCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:10405:17879/1
+GTATCCGACATCTGGTTCCT
++
+CBCCCFCCCCCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:13493:8205/1
+GTAGCTAAAGTGAACTGTAT
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:14060:21273/1
+GTATCCGACATCTGGTTCCT
++
+AAABAFCCCCCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:14528:12993/1
+GCCCATAACACTTGGGGGTA
++
+BBBBBFFFBDFFGFBCG2EG
+@M01368:8:000000000-A3GHV:1:1103:17657:20856/1
+AAAGCGAACTGTATCCGACA
++
+ABB?AABBBBFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:23099:3794/1
+AAGACAGATACTGCGACATA
++
+BBBBBFFFFFFFGGEEGGFG
+@M01368:8:000000000-A3GHV:1:1103:25465:20010/1
+GACATAGGGTGCTCCGGCTC
++
+ABBBBFFFFBAAGGGFEFGG
+@M01368:8:000000000-A3GHV:1:1103:25519:6301/1
+AAATAAGACATCACGATGGA
++
+3A3AAFFFFBFFGGG2CF?4
+@M01368:8:000000000-A3GHV:1:1103:6074:6549/1
+TAACACTTGGGGGTAGCTAA
++
+CCCBCFFFFFCCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:11572:8264/1
+GTATCCGACATCTGGTTCCT
++
+BABCBFBACCCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:11928:24197/1
+ACGTAGGTGCGATAAATAAT
++
+CDDCCFCFFFBCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:12288:20635/1
+CACTTGGGGGTAGCTAAAGT
++
+ABA?AFBAB2>AFGGGGFFG
+@M01368:8:000000000-A3GHV:1:1104:13832:4398/1
+CACGATGGATCACAGGTCTA
++
+AAABABCAFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:23670:4161/1
+ATTCAATTGTTATTATTATG
++
+AAAABFFFFFFFGGGGGGGC
+@M01368:8:000000000-A3GHV:1:1104:24927:22253/1
+AGCTAAAGTGAACTGTATCC
++
+AAA?AFFF3DFFFGGBGFF3
+@M01368:8:000000000-A3GHV:1:1104:4705:7727/1
+CTACAAGCATTAATTAATTA
++
+BBBBBFFBFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:7756:4776/1
+GGCCCATAACACTTGGGGGT
++
+CCCCCCFFFFFFGGGGGGGE
+@M01368:8:000000000-A3GHV:1:1105:11310:21761/1
+ATAAATAATAGGATGAGGCA
++
+CCCCBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:11578:14676/1
+ATTGAACGTAGGTGCGATAA
++
+CDDDDFFFBFFCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:13575:19255/1
+TTAGTAAGTATGTTCGCCTG
++
+AA1A1DFFFFFBGG3A111F
+@M01368:8:000000000-A3GHV:1:1105:15502:11453/1
+GTCCTACAAGCATTAATTAA
++
+A3AAAFFFFFCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:16787:9771/1
+GTTATTATTATGTCCTACAA
++
+AABCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:17564:15723/1
+TATGCTCGCCTGTAATATTG
++
+EDCCDFFCEEDCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:18108:12091/1
+TAATAGGATGAGGCAGGAAT
++
+CCCCCFBFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:18331:16683/1
+TCTGGTTCCTACTTCAGGGT
++
+BABA?DFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:20577:18421/1
+GGGGGTAGCTAAAGTGAACT
++
+ABB@3>AAFFFFFEAGGGFG
+@M01368:8:000000000-A3GHV:1:1105:21099:2895/1
+TAGCTAAAGTGAACTGTATC
++
+CBCBBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:26469:19245/1
+TTATGATTATGTCCTACAAG
++
+BAAAAFFFBFFFGGGGGGFF
+@M01368:8:000000000-A3GHV:1:1105:7169:17145/1
+AACCTAAATAGCCCACACGT
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1106:15481:16176/1
+CTTTAGTAAGTATGTTCGCC
++
+ABBBBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1106:17389:18671/1
+CCATAACACTTGGGGGTAGC
++
+3>>A@FFFFFFFGGGFEECF
+@M01368:8:000000000-A3GHV:1:1106:22927:3863/1
+GTATCCGACATCTGGTTCCT
++
+A>ABAFA?D@AFGGGGFGGG
+@M01368:8:000000000-A3GHV:1:1106:23625:4236/1
+TAGCTAAAGTGAACTGTATC
++
+@?AAAFFBFBFFFGGFGFGG
+@M01368:8:000000000-A3GHV:1:1106:26031:14826/1
+GATCACAGGTCTATCACCCT
++
+ABBAAFFF@FFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1106:27607:15990/1
+GACAGATACTGCGACATAGG
++
+BBBBBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1106:6455:17124/1
+GTATCCGACATCTGGTTCCT
++
+BBBAAFABDBBFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:14451:26748/1
+GTATGTTCGCCTGTAATATT
++
+BABBBFFDABBBGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:18714:24788/1
+GTATGTTCGCCTGTAATATT
++
+BBBCCFFFDEDEGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:21355:8333/1
+ATATTGAACGTAGGTGCGAT
++
+ABCBBFFFFFAFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:22864:15712/1
+AATAAGACATCACGATGGAT
++
+BBBBBFBBFFFFGGGGCEGG
+@M01368:8:000000000-A3GHV:1:1107:24817:14233/1
+CTTCAGGGTCATAAAACCTA
++
+3AABABFFBFFFGCFGGGGG
+@M01368:8:000000000-A3GHV:1:1107:24830:14440/1
+AACTGTATCCGACATCTGGT
++
+ABBBA@FFFFBBGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:26478:23602/1
+GCTAAAGTGAACTGTATCCG
++
+1AAAAF1B13BBBEGGGFGG
+@M01368:8:000000000-A3GHV:1:1108:11059:23181/1
+GTTATTATTATGTCCTACAA
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1108:12233:13498/1
+TAGGTGCGATAAATAATAGG
++
+BCCBAFFBCCCCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1108:14328:14751/1
+ATAATAGGATGAGGCAGGAA
++
+BCCCBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1108:16350:22621/1
+TTAGTAAGTATGTTCGCCTG
++
+AAAACFFFFFFFGGGFGGGG
+@M01368:8:000000000-A3GHV:1:1108:21791:23272/1
+CTTTAGTAAGTATGTTCGCC
++
+3ABBBFFFFF@FGGGGGGGC
+@M01368:8:000000000-A3GHV:1:1108:23314:26089/1
+ATTGAACGTAGGTGCGATAA
++
+BBBBBFFF?FFAGFBFGGEG
+@M01368:8:000000000-A3GHV:1:1108:25084:18127/1
+TTATTATGTCCTACAAGCAT
++
+CCBBCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1108:7626:10048/1
+ATCAAAGACAGATACTGCGA
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1109:11270:12255/1
+AATCAAAGACAGATACTGCG
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1109:19224:11655/1
+AAATAGCCCACACGTTCCCC
++
+BBB@A4FFFBBBGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1109:21978:9490/1
+GGGTCATAAAACCTAAATAG
++
+?A3AA?DFFFFFGGGGGGGF
+@M01368:8:000000000-A3GHV:1:1109:22910:4079/1
+TAATAGGATGAGGCAGGAAT
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1109:24217:19077/1
+AAAGTGAACTGTATCCGACA
++
+>AAA3BDFFFFDGBFFEEGG
+@M01368:8:000000000-A3GHV:1:1109:25237:11722/1
+CCTGTAATATTGAACGTAGG
++
+AABBBFFFFFBBF5BGGFGA
+@M01368:8:000000000-A3GHV:1:1109:27103:7153/1
+GTAATATTGAACGTAGGTGC
++
+33>A?FFFDFBFGCG4EGFG
+@M01368:8:000000000-A3GHV:1:1109:8763:7859/1
+TAGTAAGTATGTTCGCCTGT
++
+BABAADFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1110:12808:18367/1
+AATTAACACACTTTAGTAAG
++
+BBBBBFFFFBBFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1110:14751:26540/1
+TAACACTTGGGGGTAGCTAA
++
+AAA?1CFFFFADGEEGFGB1
+@M01368:8:000000000-A3GHV:1:1110:15519:10008/1
+CTGTAATATTGAACGTAGGT
++
+BBBBBFFFFFFFGGGGGGCB
+@M01368:8:000000000-A3GHV:1:1110:16559:7507/1
+CATTCAATTGTTATTATTAT
++
+ABBBAFFFFFFFFGGGGGGG
+@M01368:8:000000000-A3GHV:1:1110:16700:6843/1
+AAATAATAGGATGAGGCAGG
++
+BBBBBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1110:18014:7856/1
+ATAAATAATAGGATGAGGCA
++
+AABBBFFFFFFFCGGGCGGG
+@M01368:8:000000000-A3GHV:1:1110:23303:11846/1
+ACTTGGGGGTAGCTAAAGTG
++
+3ABB?FAB?DAAGGGFBGGB
+@M01368:8:000000000-A3GHV:1:1111:13195:14562/1
+ATCAAAGACAGATACTGCGA
++
+ABAAAFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1111:14287:20817/1
+GCCAACACGTTCCCCTTAAA
++
+>>A3>AAAACFFFGFGFGGG
+@M01368:8:000000000-A3GHV:1:1111:23624:14516/1
+GTCCTACAAGCATTAATTAA
++
+3>3AAFFFFFAFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1111:7437:24508/1
+ACACACTTTAGTAAGTATGT
++
+CBCCDCFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1111:8665:25542/1
+TCCTACTTCAGGGTCATAAA
++
+AA3AAFFFFFFFGGGFGFFG
+@M01368:8:000000000-A3GHV:1:1111:9655:13916/1
+GGCCCATAACACTTGGGGGT
++
+1>>1AAFFFFFBGGFE1EEE
+@M01368:8:000000000-A3GHV:1:1112:10272:7828/1
+GTATCCGACATCTGGTTCCT
++
+AAABABBBBBBFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1112:9832:16531/1
+CTGTAATATTGAACGTAGGT
++
+AABABFFFFFFFF4GGGGEB
+@M01368:8:000000000-A3GHV:1:1112:9832:6701/1
+CGCCTGTAATATTGAACGTA
++
+AABBBBFFFFFFGGGFGGGG
+@M01368:8:000000000-A3GHV:1:1113:13532:8618/1
+GGAATCAAAGACAGATACTG
++
+AA?AAFFFFFFFGGGGGFBF
+@M01368:8:000000000-A3GHV:1:1113:21679:18011/1
+GATCACAGGTCTATCACCCT
++
+AA>1>11F1D1DDFFFFGGG
+@M01368:8:000000000-A3GHV:1:1113:25528:14016/1
+CCTACAAGCATTAATTAATT
++
+>AAAAFFFBFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1113:5741:16959/1
+TAGTAAGTATGTTCGCCTGT
++
+ABBBBFFFFFFFGGGFGGGG
+@M01368:8:000000000-A3GHV:1:1114:10130:11959/1
+CGTTCCCCTTAAATAAGACA
++
+>A33>FFFFFF@FFFGGGGF
+@M01368:8:000000000-A3GHV:1:1114:14540:5315/1
+CTTTAGTAAGTATGTTCGCC
++
+AABCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1114:15066:16302/1
+TAAATAAGACATCACGATGG
++
+BBBBAFFBDFBFBGGGGGFG
+@M01368:8:000000000-A3GHV:1:1114:16639:15258/1
+CCTAAATAGCCCACACGTTC
++
+11>>ABFFFFFFGGCGC1BB
+@M01368:8:000000000-A3GHV:1:1114:2404:13066/1
+TCCTACAAGCATTAATTAAT
++
+CCCCCFFFFCFFGGGGGGGG
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/paired_hardtrimmed5_pair2_.fastqsanger
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/paired_hardtrimmed5_pair2_.fastqsanger	Fri Oct 08 09:57:12 2021 +0000
@@ -0,0 +1,396 @@
+@M01368:8:000000000-A3GHV:1:1101:6911:8255/1
+ATCTGGTTCCTACTTCAGGG
++
+BCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1101:14518:9998/1
+GTTATTATTATGTCCTACAA
++
+AAAAAFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1101:18422:19051/1
+GTATCCGACATCTGGTTCCT
++
+CCCCCFDDDDDFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1101:25545:21098/1
+ATTAATTAACACACTTTAGT
++
+33AA?DFD5BDFGGGFEBDG
+@M01368:8:000000000-A3GHV:1:1101:5446:12248/1
+AATTAACACACTTTAGTAAG
++
+CCCCDFFFFCCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1101:5861:6452/1
+ATTATGTCCTACAAGCATTA
++
+ABCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:10403:6021/1
+CGCTCCGGGCCCATAACACT
++
+>A@AAAAD2ADDFFGGGGGF
+@M01368:8:000000000-A3GHV:1:1102:10677:23253/1
+CCTTAAATAAGACATCACGA
++
+ABBBBFFFFFFFGGGGGGGC
+@M01368:8:000000000-A3GHV:1:1102:13809:1733/1
+ATATTGAACGTAGGTGCGAT
++
+BCCBCFFFFFBFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:17584:10050/1
+ATCAAAGACAGATACTGCGA
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:18842:24844/1
+CACTTGGGGGTAGCTAAAGT
++
+BBBCBFF@CCBBGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:21788:11027/1
+GCCCACACGTTCCCCTTAAA
++
+ABCCBCCBBFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:5728:8777/1
+ATATTGAACGTAGGTGCGAT
++
+BBBBBFFFFFAFGG5GGGGG
+@M01368:8:000000000-A3GHV:1:1102:5983:21093/1
+GTATCCGACATCTGGTTCCT
++
+AAABCFCABBCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1102:7765:18353/1
+CTCCGGGCCCATAACACTTG
++
+CCDCCCCCCBCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:10405:17879/1
+GTATCCGACATCTGGTTCCT
++
+CBCCCFCCCCCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:13493:8205/1
+GTAGCTAAAGTGAACTGTAT
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:14060:21273/1
+GTATCCGACATCTGGTTCCT
++
+AAABAFCCCCCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:14528:12993/1
+GCCCATAACACTTGGGGGTA
++
+BBBBBFFFBDFFGFBCG2EG
+@M01368:8:000000000-A3GHV:1:1103:17657:20856/1
+AAAGCGAACTGTATCCGACA
++
+ABB?AABBBBFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1103:23099:3794/1
+AAGACAGATACTGCGACATA
++
+BBBBBFFFFFFFGGEEGGFG
+@M01368:8:000000000-A3GHV:1:1103:25465:20010/1
+GACATAGGGTGCTCCGGCTC
++
+ABBBBFFFFBAAGGGFEFGG
+@M01368:8:000000000-A3GHV:1:1103:25519:6301/1
+AAATAAGACATCACGATGGA
++
+3A3AAFFFFBFFGGG2CF?4
+@M01368:8:000000000-A3GHV:1:1103:6074:6549/1
+TAACACTTGGGGGTAGCTAA
++
+CCCBCFFFFFCCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:11572:8264/1
+GTATCCGACATCTGGTTCCT
++
+BABCBFBACCCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:11928:24197/1
+ACGTAGGTGCGATAAATAAT
++
+CDDCCFCFFFBCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:12288:20635/1
+CACTTGGGGGTAGCTAAAGT
++
+ABA?AFBAB2>AFGGGGFFG
+@M01368:8:000000000-A3GHV:1:1104:13832:4398/1
+CACGATGGATCACAGGTCTA
++
+AAABABCAFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:23670:4161/1
+ATTCAATTGTTATTATTATG
++
+AAAABFFFFFFFGGGGGGGC
+@M01368:8:000000000-A3GHV:1:1104:24927:22253/1
+AGCTAAAGTGAACTGTATCC
++
+AAA?AFFF3DFFFGGBGFF3
+@M01368:8:000000000-A3GHV:1:1104:4705:7727/1
+CTACAAGCATTAATTAATTA
++
+BBBBBFFBFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1104:7756:4776/1
+GGCCCATAACACTTGGGGGT
++
+CCCCCCFFFFFFGGGGGGGE
+@M01368:8:000000000-A3GHV:1:1105:11310:21761/1
+ATAAATAATAGGATGAGGCA
++
+CCCCBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:11578:14676/1
+ATTGAACGTAGGTGCGATAA
++
+CDDDDFFFBFFCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:13575:19255/1
+TTAGTAAGTATGTTCGCCTG
++
+AA1A1DFFFFFBGG3A111F
+@M01368:8:000000000-A3GHV:1:1105:15502:11453/1
+GTCCTACAAGCATTAATTAA
++
+A3AAAFFFFFCFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:16787:9771/1
+GTTATTATTATGTCCTACAA
++
+AABCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:17564:15723/1
+TATGCTCGCCTGTAATATTG
++
+EDCCDFFCEEDCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:18108:12091/1
+TAATAGGATGAGGCAGGAAT
++
+CCCCCFBFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:18331:16683/1
+TCTGGTTCCTACTTCAGGGT
++
+BABA?DFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:20577:18421/1
+GGGGGTAGCTAAAGTGAACT
++
+ABB@3>AAFFFFFEAGGGFG
+@M01368:8:000000000-A3GHV:1:1105:21099:2895/1
+TAGCTAAAGTGAACTGTATC
++
+CBCBBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1105:26469:19245/1
+TTATGATTATGTCCTACAAG
++
+BAAAAFFFBFFFGGGGGGFF
+@M01368:8:000000000-A3GHV:1:1105:7169:17145/1
+AACCTAAATAGCCCACACGT
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1106:15481:16176/1
+CTTTAGTAAGTATGTTCGCC
++
+ABBBBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1106:17389:18671/1
+CCATAACACTTGGGGGTAGC
++
+3>>A@FFFFFFFGGGFEECF
+@M01368:8:000000000-A3GHV:1:1106:22927:3863/1
+GTATCCGACATCTGGTTCCT
++
+A>ABAFA?D@AFGGGGFGGG
+@M01368:8:000000000-A3GHV:1:1106:23625:4236/1
+TAGCTAAAGTGAACTGTATC
++
+@?AAAFFBFBFFFGGFGFGG
+@M01368:8:000000000-A3GHV:1:1106:26031:14826/1
+GATCACAGGTCTATCACCCT
++
+ABBAAFFF@FFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1106:27607:15990/1
+GACAGATACTGCGACATAGG
++
+BBBBBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1106:6455:17124/1
+GTATCCGACATCTGGTTCCT
++
+BBBAAFABDBBFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:14451:26748/1
+GTATGTTCGCCTGTAATATT
++
+BABBBFFDABBBGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:18714:24788/1
+GTATGTTCGCCTGTAATATT
++
+BBBCCFFFDEDEGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:21355:8333/1
+ATATTGAACGTAGGTGCGAT
++
+ABCBBFFFFFAFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:22864:15712/1
+AATAAGACATCACGATGGAT
++
+BBBBBFBBFFFFGGGGCEGG
+@M01368:8:000000000-A3GHV:1:1107:24817:14233/1
+CTTCAGGGTCATAAAACCTA
++
+3AABABFFBFFFGCFGGGGG
+@M01368:8:000000000-A3GHV:1:1107:24830:14440/1
+AACTGTATCCGACATCTGGT
++
+ABBBA@FFFFBBGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1107:26478:23602/1
+GCTAAAGTGAACTGTATCCG
++
+1AAAAF1B13BBBEGGGFGG
+@M01368:8:000000000-A3GHV:1:1108:11059:23181/1
+GTTATTATTATGTCCTACAA
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1108:12233:13498/1
+TAGGTGCGATAAATAATAGG
++
+BCCBAFFBCCCCGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1108:14328:14751/1
+ATAATAGGATGAGGCAGGAA
++
+BCCCBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1108:16350:22621/1
+TTAGTAAGTATGTTCGCCTG
++
+AAAACFFFFFFFGGGFGGGG
+@M01368:8:000000000-A3GHV:1:1108:21791:23272/1
+CTTTAGTAAGTATGTTCGCC
++
+3ABBBFFFFF@FGGGGGGGC
+@M01368:8:000000000-A3GHV:1:1108:23314:26089/1
+ATTGAACGTAGGTGCGATAA
++
+BBBBBFFF?FFAGFBFGGEG
+@M01368:8:000000000-A3GHV:1:1108:25084:18127/1
+TTATTATGTCCTACAAGCAT
++
+CCBBCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1108:7626:10048/1
+ATCAAAGACAGATACTGCGA
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1109:11270:12255/1
+AATCAAAGACAGATACTGCG
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1109:19224:11655/1
+AAATAGCCCACACGTTCCCC
++
+BBB@A4FFFBBBGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1109:21978:9490/1
+GGGTCATAAAACCTAAATAG
++
+?A3AA?DFFFFFGGGGGGGF
+@M01368:8:000000000-A3GHV:1:1109:22910:4079/1
+TAATAGGATGAGGCAGGAAT
++
+CCCCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1109:24217:19077/1
+AAAGTGAACTGTATCCGACA
++
+>AAA3BDFFFFDGBFFEEGG
+@M01368:8:000000000-A3GHV:1:1109:25237:11722/1
+CCTGTAATATTGAACGTAGG
++
+AABBBFFFFFBBF5BGGFGA
+@M01368:8:000000000-A3GHV:1:1109:27103:7153/1
+GTAATATTGAACGTAGGTGC
++
+33>A?FFFDFBFGCG4EGFG
+@M01368:8:000000000-A3GHV:1:1109:8763:7859/1
+TAGTAAGTATGTTCGCCTGT
++
+BABAADFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1110:12808:18367/1
+AATTAACACACTTTAGTAAG
++
+BBBBBFFFFBBFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1110:14751:26540/1
+TAACACTTGGGGGTAGCTAA
++
+AAA?1CFFFFADGEEGFGB1
+@M01368:8:000000000-A3GHV:1:1110:15519:10008/1
+CTGTAATATTGAACGTAGGT
++
+BBBBBFFFFFFFGGGGGGCB
+@M01368:8:000000000-A3GHV:1:1110:16559:7507/1
+CATTCAATTGTTATTATTAT
++
+ABBBAFFFFFFFFGGGGGGG
+@M01368:8:000000000-A3GHV:1:1110:16700:6843/1
+AAATAATAGGATGAGGCAGG
++
+BBBBBFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1110:18014:7856/1
+ATAAATAATAGGATGAGGCA
++
+AABBBFFFFFFFCGGGCGGG
+@M01368:8:000000000-A3GHV:1:1110:23303:11846/1
+ACTTGGGGGTAGCTAAAGTG
++
+3ABB?FAB?DAAGGGFBGGB
+@M01368:8:000000000-A3GHV:1:1111:13195:14562/1
+ATCAAAGACAGATACTGCGA
++
+ABAAAFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1111:14287:20817/1
+GCCAACACGTTCCCCTTAAA
++
+>>A3>AAAACFFFGFGFGGG
+@M01368:8:000000000-A3GHV:1:1111:23624:14516/1
+GTCCTACAAGCATTAATTAA
++
+3>3AAFFFFFAFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1111:7437:24508/1
+ACACACTTTAGTAAGTATGT
++
+CBCCDCFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1111:8665:25542/1
+TCCTACTTCAGGGTCATAAA
++
+AA3AAFFFFFFFGGGFGFFG
+@M01368:8:000000000-A3GHV:1:1111:9655:13916/1
+GGCCCATAACACTTGGGGGT
++
+1>>1AAFFFFFBGGFE1EEE
+@M01368:8:000000000-A3GHV:1:1112:10272:7828/1
+GTATCCGACATCTGGTTCCT
++
+AAABABBBBBBFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1112:9832:16531/1
+CTGTAATATTGAACGTAGGT
++
+AABABFFFFFFFF4GGGGEB
+@M01368:8:000000000-A3GHV:1:1112:9832:6701/1
+CGCCTGTAATATTGAACGTA
++
+AABBBBFFFFFFGGGFGGGG
+@M01368:8:000000000-A3GHV:1:1113:13532:8618/1
+GGAATCAAAGACAGATACTG
++
+AA?AAFFFFFFFGGGGGFBF
+@M01368:8:000000000-A3GHV:1:1113:21679:18011/1
+GATCACAGGTCTATCACCCT
++
+AA>1>11F1D1DDFFFFGGG
+@M01368:8:000000000-A3GHV:1:1113:25528:14016/1
+CCTACAAGCATTAATTAATT
++
+>AAAAFFFBFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1113:5741:16959/1
+TAGTAAGTATGTTCGCCTGT
++
+ABBBBFFFFFFFGGGFGGGG
+@M01368:8:000000000-A3GHV:1:1114:10130:11959/1
+CGTTCCCCTTAAATAAGACA
++
+>A33>FFFFFF@FFFGGGGF
+@M01368:8:000000000-A3GHV:1:1114:14540:5315/1
+CTTTAGTAAGTATGTTCGCC
++
+AABCCFFFFFFFGGGGGGGG
+@M01368:8:000000000-A3GHV:1:1114:15066:16302/1
+TAAATAAGACATCACGATGG
++
+BBBBAFFBDFBFBGGGGGFG
+@M01368:8:000000000-A3GHV:1:1114:16639:15258/1
+CCTAAATAGCCCACACGTTC
++
+11>>ABFFFFFFGGCGC1BB
+@M01368:8:000000000-A3GHV:1:1114:2404:13066/1
+TCCTACAAGCATTAATTAAT
++
+CCCCCFFFFCFFGGGGGGGG
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/sanger_full_range_report_results1.txt
--- a/test-data/sanger_full_range_report_results1.txt	Tue Jul 30 06:26:22 2019 -0400
+++ b/test-data/sanger_full_range_report_results1.txt	Fri Oct 08 09:57:12 2021 +0000
@@ -3,21 +3,24 @@
 ==========================
 Input filename: input_1.fastq
 Trimming mode: single-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Unable to auto-detect most prominent adapter from the first specified file (count Nextera: 0, count smallRNA: 0, count Illumina: 0)
+Defaulting to Illumina universal adapter ( AGATCGGAAGAGC ). Specify -a SEQUENCE to avoid this behavior).
 Adapter sequence: 'AGATCGGAAGAGC' (Illumina TruSeq, Sanger iPCR; default (inconclusive auto-detection))
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
 Minimum required sequence length before a sequence gets removed: 20 bp
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a AGATCGGAAGAGC input_1.fastq
-Processing reads on 1 core in single-end mode ...
-Finished in 0.00 s (1608 us/read; 0.04 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a AGATCGGAAGAGC input_1.fastq
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.01 s (5282 µs/read; 0.01 M reads/minute).
 
 === Summary ===
 
@@ -31,10 +34,10 @@
 
 === Adapter 1 ===
 
-Sequence: AGATCGGAAGAGC; Type: regular 3'; Length: 13; Trimmed: 1 times.
+Sequence: AGATCGGAAGAGC; Type: regular 3'; Length: 13; Trimmed: 1 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-13 bp: 1
+1-9 bp: 0; 10-13 bp: 1
 
 Bases preceding removed adapters:
   A: 0.0%
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/sanger_full_range_report_results1gz.txt
--- a/test-data/sanger_full_range_report_results1gz.txt	Tue Jul 30 06:26:22 2019 -0400
+++ b/test-data/sanger_full_range_report_results1gz.txt	Fri Oct 08 09:57:12 2021 +0000
@@ -3,11 +3,14 @@
 ==========================
 Input filename: input_1.fastq.gz
 Trimming mode: single-end
-Trim Galore version: 0.6.3
-Cutadapt version: 2.4
-Number of cores used for trimming: 1
+Trim Galore version: 0.6.7
+Cutadapt version: 3.4
+Python version: could not detect
+Number of cores used for trimming: 4
 Quality Phred score cutoff: 20
 Quality encoding type selected: ASCII+33
+Unable to auto-detect most prominent adapter from the first specified file (count Illumina: 0, count Nextera: 0, count smallRNA: 0)
+Defaulting to Illumina universal adapter ( AGATCGGAAGAGC ). Specify -a SEQUENCE to avoid this behavior).
 Adapter sequence: 'AGATCGGAAGAGC' (Illumina TruSeq, Sanger iPCR; default (inconclusive auto-detection))
 Maximum trimming error rate: 0.1 (default)
 Minimum required adapter overlap (stringency): 1 bp
@@ -15,10 +18,10 @@
 Output file will be GZIP compressed
 
 
-This is cutadapt 2.4 with Python 3.7.3
-Command line parameters: -j 1 -e 0.1 -q 20 -O 1 -a AGATCGGAAGAGC input_1.fastq.gz
-Processing reads on 1 core in single-end mode ...
-Finished in 0.02 s (7871 us/read; 0.01 M reads/minute).
+This is cutadapt 3.4 with Python 3.9.6
+Command line parameters: -j 4 -e 0.1 -q 20 -O 1 -a AGATCGGAAGAGC input_1.fastq.gz
+Processing reads on 4 cores in single-end mode ...
+Finished in 0.01 s (5217 µs/read; 0.01 M reads/minute).
 
 === Summary ===
 
@@ -32,10 +35,10 @@
 
 === Adapter 1 ===
 
-Sequence: AGATCGGAAGAGC; Type: regular 3'; Length: 13; Trimmed: 1 times.
+Sequence: AGATCGGAAGAGC; Type: regular 3'; Length: 13; Trimmed: 1 times
 
 No. of allowed errors:
-0-9 bp: 0; 10-13 bp: 1
+1-9 bp: 0; 10-13 bp: 1
 
 Bases preceding removed adapters:
   A: 0.0%
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/sanger_full_range_results1.fastq.gz
Binary file test-data/sanger_full_range_results1.fastq.gz has changed
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/sanger_full_range_results2.fastq.gz
Binary file test-data/sanger_full_range_results2.fastq.gz has changed
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/sanger_full_range_results3.fastq.gz
Binary file test-data/sanger_full_range_results3.fastq.gz has changed
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/trimmed_polyA_reads_pair1.fastqsanger
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/trimmed_polyA_reads_pair1.fastqsanger	Fri Oct 08 09:57:12 2021 +0000
@@ -0,0 +1,396 @@
+@M01368:8:000000000-A3GHV:1:1101:6911:8255/1
+ATCTGGTTCCTACTTCAGGGCCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATT
++
+BCCCCFFFFFFFGGGGGGGGGGGHHHHGHGHHHHHHHHHGGGGGGHHHHGHHHHHHHHHHGHHHHHHGGHGGHHHGHHHHFHHGHHHHHHHHHGHEHEFFGHHEGGCEFGGFHHHBGHHGHHHHGHFHHHGHGHGHGGCDFDDACGGGGGGGAAFFFFFFFFFBAFFFFFB;FFFFFFADDFFFFFFFFFFEFFFFFFFFFFBFFFFFFFFFFFFFFEFFFFFFFFBFEFFFFEFE;DFFFDFBFF/9BFB
+@M01368:8:000000000-A3GHV:1:1101:14518:9998/1
+GTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGAT
++
+AAAAAFFFFFFFGGGGGGGGGGHGGHHHHGHHHHHHHGCGHHHHHHHHHHHHHHHGGGGGHHHHHHHHHGHHGFHFE5BGEEHFGGGHHHHHHHHFBHHGGGGFHGHHFGHHHHGHHHHHHGEGGGGFHFHGEGHHGGCDGDGHGGGDGGHGGCGGGHGHHH/ACDG?.1FGCDCCGCA.CC@CDCHFHGFFGGGEBFGAB//CEFBFGG.:;D;;A0AFFFFFB..:@ABFF//;BFFFFFBF/9D:A//
+@M01368:8:000000000-A3GHV:1:1101:18422:19051/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+CCCCCFDDDDDFGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHFHHHHGGGGHHHHHHHHHGHHHHHHHHHHHHGGHGGHHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHGCGGGHHHHHHHHHHHHHHHHHHHHHHGFDHGFHCFGGGGFGGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF;FFFFFFFFFFFFFFFFFFFFFFFFFFFFEFBFFFFFFFFFF:FFF.
+@M01368:8:000000000-A3GHV:1:1101:25545:21098/1
+ATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATAAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGGCTTATTTAAGGGGAACGGGTGGGG
++
+33AA?DFD5BDFGGGFEBDGEGHEGHGEGHCEGGHHCHGHHFFHHGFGAGE53FF2FAFFGDE5FFFE5GFBFGAEE1GHHHGHHHEHE3FGHF@GEGEGGHHGG3FAGFFDE?EEE3GFEGFGFGGCG?GHHHFHGGGC@DHFFHD/A<C@EGFDCGGGHFHHHEGFGHBFHG0:CEHFCHGGED.;0CEF.F99B0CFFEEFGGG0FBFBBF0F/FFBDE?/9//9B.FFBFFFFFFBF..A..;@B--
+@M01368:8:000000000-A3GHV:1:1101:5446:12248/1
+AATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTAT
++
+CCCCDFFFFCCFGGGGGGGGFGHHHHHGGGGHHHHHHHHHHHHHHHHGBGHGGHGGHHHHHHHHHHGHGHGGGGGHHHHHHHHGHHHHHHHHHGGGGGHHHHFFGHHHGGGGGGHHHGFGGHHGGGGHHHHHHGGGGGGHGHHGGGGGGGHGGGGGGHHHHHHHHHHHHHFHGGGHHHHGGGGGG:FE;EGEGGGGG/;?FGGGGGGGFFFFGGFFFFFFFFFBFFFFFFFFFFBFFFFFFEFFFFFEFFF
+@M01368:8:000000000-A3GHV:1:1101:5861:6452/1
+ATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTT
++
+ABCCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHGHHHHGHHHHHHHHHHHGGGGHHHHHHHHFHHHHHHGGHGHGGHGGHHHHHHHGGHFHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHHEGGHHGGGGGGHHHGGGGHGGGGGHHHHHHGGGDCGHHHHGGGGGGGHEFGGGGHGHHHGHGGGFGGGGGGGEGGGGGGG?E0CEFGGGGGFEE9EEFFFFFBFFFFFFFBFFBD.AFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1102:10403:6021/1
+CGCTCCGGGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTG
++
+>A@AAAAD2ADDFFGGGGGFGGHA?EAEFBEAGHFABFGG5FDF5DB1EEGAFDFB53FF5FH@G5FFEHGHEFHFFHBE333GF43GCGGGGE@0?BFGGB0B?FHGFDGGHHHBFFDEGGHGFFFDFE@<1>@FFFGHHHHFHEFGDABFFGG/@DCE<CG1<GF0/DD000=<DHGBDFDCECE/:AC?-;-;9B/ABBB-AD9BFB99AB?BDFBAD-.9..@;=;;..9..9/9;BEF;A:9/BFF
+@1:A:M01368:8:000000000-A3GHV:1:1102:10677:23253/1_PolyA:1
+CCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTCTGTCTCTTATACAC
++
+ABBBBFFFFFFFGGGGGGGCGGGHHHHHGHHHHHHHHHGHHHHHHHHHHHGHHHHHGGGGGHGHHHHHHHHHHHHHBGFHHHHGHGHGGHGGGCGGGHHHGGGGGGGHHHGHGGGGGGGGGGGGGGGGGGGGFFFFFFFFFFFFFFDFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBFFFFFFFFFEDBDFFFFFFFEFFFE0F0FBFFFF0FFFFFFFFFFFFFFFFF
+@M01368:8:000000000-A3GHV:1:1102:13809:1733/1
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGAGGGCTATTTAGGTTTTATGCTGTCTCTTATACACATCTCCG
++
+BCCBCFFFFFBFGGGGGGGGGGHHHHHHHHHHHGHHGGGGGH3EHHHGHGHHHHHHHHHGGCEGGGHHHGGGFHGGGGGGHHGEAEFHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGCFFGHHFGHHHGHHHHHHCHGFHHHHGGHGGG00EHGHHHGFHHGEHGHFFFHHGGFHHHGGGGGGGGGB;;CFFGGFGFFBFFDFED;E.:A?DFFFFFFFF:FFFFF0BFFBBBFFFFFBFF0BFBF9F.
+@M01368:8:000000000-A3GHV:1:1102:17584:10050/1
+ATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCT
++
+CCCCCFFFFFFFGGGGGGGGGGGHHHHHGGHHHGGGGGGHHHGFGDHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGEGGHHHHHHHGHGHHGHHHHGHHHHGGGGFDGHFHGEHHHHHHGFFHHHHHHHHHHHHHHHHHGGHHHHHHHHHHFHHHHHHGGGGGHHHHGGGHHGHHHGGGGGGGGGGGFGFFGGGGGGGCFGGGFGGGGGGGFFFFFFFFFFFFFFFFFFF;.BF9ADF/9;A;DFFF0
+@M01368:8:000000000-A3GHV:1:1102:18842:24844/1
+CACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCT
++
+BBBCBFF@CCBBGGGGGGGGGGHHGHGGHHHGGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHHFHHHHGGGGGHHHHHHHHHHHHHHHHHHHHGGGHGGHHHHHHGHBFGHHHHHHHHBGHHHHHHGHGGGHFGCGGFHHFHFFHHBHHHHFFHFHHHHGGDHGGBC?;@DFBFFFFFFFFFBFFFFFFFFFFFFFF.B?FB.@;;DFFFFFFFFFFFEE-A./BBBFBFBFFF//BFB/BFF/
+@M01368:8:000000000-A3GHV:1:1102:21788:11027/1
+GCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTCTG
++
+ABCCBCCBBFFFGGGGGGGGGGGHGHHHHHHGGHGGHHHHHHHHGHHHHHHHHHHHHHHHHHHGHHHHHFGGGGHHHHHHHHHHHHHHHHHHHHHHGHGHGGFCGGCGGGHHHGGGGGGGGGGGGGGGGGGGGGGGGGFFFFFFFFFFFFFFFFFFFFFDFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEF9EFFFFFFFFFFFBFF0FFBBBBFBFBFFFF0
+@M01368:8:000000000-A3GHV:1:1102:5728:8777/1
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATG
++
+BBBBBFFFFFAFGG5GGGGGGGHHHGHHHHHHHHHHGGGGGHHHHHHGHHHHHHFGHHHGGGGGFHGHGGGHHHGGGCEGHHGG?F1BGGGGGHHHHHGGGGEGGHHHHGGGGGCGHGGGGCGHHHHHHHHHHHHHHHHGGHHHHGGCEEDFDEGGHHHHHHHCEHHFHHHHGHGFHHHFFGGGFFFGGFGBGFFFFFFFFGFDGGD9EFA.DAFA/;FEFF9FB?/BBF/FFFFBBFFFFF/FFEFFFBB
+@M01368:8:000000000-A3GHV:1:1102:5983:21093/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+AAABCFCABBCFGGGGGGGGGGHHHHHHGFHHHHHHHHGGHHHGHGHHHGGGGFHHHHHHHHGHHHHHHHHHHHHHGGHGGHHHHHHFHGGHHHHFHGHHEHHHHHHHGHHHHHD@FGGHHHHHFFFHHGGHGH?DHHHHHGHGHEGG/@?ADGFGGFFFFAFFFFFFFFFFFFFFFFFFFFFFFAAFFFFFFDFFFFFFFF;D9BFFFFFFFFFFFFFFFFFEFFFBBFFF0BFFFBBFF0EFFFFFFFA
+@M01368:8:000000000-A3GHV:1:1102:7765:18353/1
+CTCCGGGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTC
++
+CCDCCCCCCBCFGGGGGGGGGGGGGGGHHHHHHDHHHHHHHHHHHGGGGGHHGHGHHHGHHHHHHFHHHHGHHHHHHGHGHHHGHHHHHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHHHHHHGFFHHHHHGHHHHHHHHHHHGHHHHHGCFGGHGHFHHGHGHGHHHHGGFHHHHGGGHGBFGCC=BFFFFFFFF-@DFFFFFFFFFFFFFFFFFFFFFFAFFAEF.::FBFBFFE-A9:BFFFF0
+@M01368:8:000000000-A3GHV:1:1103:10405:17879/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+CBCCCFCCCCCFGGGGGGGGGGHHHHHHHHHHHHGHHHGHHHHHHHHHHHGGGGGGHHHHHHHHHHHHHHHHHHHHGGHGGHHHGHHGHHGHHHHHHHHHCGGFHHHHGHHHHHGCFGGHHGHHHHHHGFHHHGHHHHHHHGHGHGFF/CC?ADAFGFFFFFFFFFFFFFFDFFFFFFFFAFFFFFFFFFFFEDFFFFFFFFFFAFFFFFFFFFFFFFFFFFFFFFFBBFBFBFFFFFFFFFFFFFFFFF?
+@M01368:8:000000000-A3GHV:1:1103:13493:8205/1
+GTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATT
++
+CCCCCFFFFFFFGGGGGGGGGGGGGGGHFHHHHHHHHHHHHHHHHGHHHHHHHHGHHHIHHHHHHHGGGGFHHHHHHHHHHHHHHHHHHHGHGGHGGHHHHHHHHHGHHHHHHHHHHHHHHHHHGHHHH/FGGGGHHHHHHHGGEHHHHHGHHHHHHGHGHEFEFGGFFFFFFFFFFFFFFFFFFFFFAFDFFFFFAFFFF;;@FFEFFFFFFFFFFE=?AFFFFFFFFFFFFFFFFFFBFBBBFFFFEFF
+@M01368:8:000000000-A3GHV:1:1103:14060:21273/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTACTGTCTCTTATACAC
++
+AAABAFCCCCCFGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHGHHHHGGGGGFHHHHHHHHHHHHHHHGHHHHGGHGGHHHHHHHHHHHHHHHHHH?GGHHHHHHGHHHHHFEGGGHHHHHHHHHHHHHHHGFHHHFHGHGHGFGCGG@@BCFGFFFFFFF?FFFFFFFFAFFFAD?@FFEEFFFFFFFFFFFFFFFFFFD9BFF/B/FFF/:/9FB9/BFA//;BFB:FFFBB/BFFFFFBFFFFB/
+@M01368:8:000000000-A3GHV:1:1103:14528:12993/1
+GCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGAT
++
+BBBBBFFFBDFFGFBCG2EGFFGHHCF5AFHHHFHFHHHGG?CEHBHHDGFHHGHHGHBGHABFFBGHGDGGGFHGHHGGHHHGGG@E1GEHHHGHHFHH3FEDHHHHGFGHGFHHGHFBGA?FGHHHHHGHHFFGHFDFGGHHH2??<ECFHHGHHHHHHHHHGHH<1DFGHGC<.FCB/<=@DCFFFFFEDA=-AAB9B/9B9B-@?.-;A-AFF.=-=BFEFEDEFFFBFEA-A.B//9F9F//;BBB
+@M01368:8:000000000-A3GHV:1:1103:17657:20856/1
+AAAGCGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTAT
++
+ABB?AABBBBFFGGGGGGGGGGHHHHHHHHGHHHHHHHHHHHHHHHHHGHHHHHHGHHHHGGGGGHHHHHHHGHHFHHHHHHHHHHGGGGGHHHHHHHH3BGGHHHHHHHEHHHHHHHGHHHHGEEGGGHHHHHHHHGHHFHGHGHGHGHHCHGGECCDFGB@AFFFFFFFFFFFFFFFFFDAFFFFFFFFFFFFFCAF;AFFFFEFFBBEFFF9FBBFFFFFFFFFFEFFFFFFFFFFFFF/FFFFBFF9
+@M01368:8:000000000-A3GHV:1:1103:23099:3794/1
+AAGACAGATACTGCGACATAGGGTGTTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCTCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGGATGCCGTCT
++
+BBBBBFFFFFFFGGEEGGFGGGGCFGEHCGGGGGGFHFFEDEHFGGDEHHHHHHGGFECGHHHHGFEFGCGHGGFGGGHBGFH3/BF3GGGHHEEEHHG22???BCFFFFFFHHFHFF@FGHH11GHHHHFGFHHHHGGHHHHEFFGFGHFG1DGFGGGGEDCCCAEGGFFHHFHHHHHHCFBBFGBFFF/0;B0B00;B0BBFGBB9BFGEFGGGFFDEEAB;BDDBFBFFFFF@;.9BF..;-./-A=F
+@M01368:8:000000000-A3GHV:1:1103:25465:20010/1
+GACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATCGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGAAAAAAAAAAAACAACAGAC
++
+ABBBBFFFFBAAGGGFEFGGGGHHFEFFHFGGGGGHHHGHFGGGGGHHHGGGGGGGGHGEEEGGHHHGFHEHFHDGHGHEHGF?FGG?GGGGHHGHF4F?2?DDCDHGHHHHHFG2@FGHHHGH?CFGGHFHFHHHHGDDGGHGGGGGHGFH.<AFAGHHHFHGHHFCGFHHHHHGHHHHBGHHGGDGAGF.CEGCFDGGGGGEFFF=B.FFFEFFFFFFADF?/9//BFF.B/;:>---;--..;.../9
+@M01368:8:000000000-A3GHV:1:1103:25519:6301/1
+AAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGCATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATTTCGT
++
+3A3AAFFFFBFFGGG2CF?4FGHGHHCHGGHHBHGFFAGGHHFFHHCGHFEGCECEGHFFFHGHHGFGHFGDAFDGFFEEFEGGBECC/<A@DFBBEGC--:;GHHHGBECG@:9-9.-9C/ABB?B@?.EDAFFFFBAFBFBFBFFFFF//;BBFFFF/;/9BBF/BBFBFFFFFFFFFEFF??BF/.AF./;B/9FFFFFFBFBFFFBFFFBFFFFF/BF/A---9.9A-B?DFFF/B/B?---.//;.
+@M01368:8:000000000-A3GHV:1:1103:6074:6549/1
+TAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTG
++
+CCCBCFFFFFCCGGGGGGGGGG5GFHHHHHGHHHGGGGGHHHGHHHHHHHHHHHHGHHHHHHHHHGGHHHHGHHHHHHGGGGHHHHHHHHHHHHHHGHHHHHHHGGHGGHHHHHHHFGHHGHGHHHHHHHHHHHHHGHHHHHGGGGCHHHHEHGHHHEGHHHFGGHHHHGHGHGHF@CCBDFAFFFFFF-CDFFFFFFFFFFFFFAFFFFFEFF;BFF?FEDFFFFFFFF-A./FFFFFFFFFFFF/BFF/
+@M01368:8:000000000-A3GHV:1:1104:11572:8264/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+BABCBFBACCCFGGGGGGGGGGGHHGHHGHHHHGFGCHGHHGFFHEHHHHGGGGFGHHHHHHHHHHHHGHHHHHHHGGGGGHHHFFHHGHHHHHHHHHHHEHHHHHHHGHHGHGGEGEGHHHFHHHHGHHHHHHGGHHHHHGHGEGEHCGG-BGDFGFFFFAFFDFFFFEFFCFFDDFFFFFFFEC>;>=EF?AEFFFF;9;=DAFFFFBBFFFBFFF//;BFB.:FBFFBB/BFFFF/BFFE?EFAFEF9
+@1:A:M01368:8:000000000-A3GHV:1:1104:11928:24197/1_PolyA:1
+ACGTAGGTGCGATAAATAATGGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGAT
++
+CDDCCFCFFFBCGGGGGGGGGGHHHGHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHGGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHHHHHGHHHHGHHGHHHHGGHGEEGGGGFHHFHHHGHGEHHHHHHHHHHHHHHHHHGGGGGGFGGGGGGGGFFGGGFGFGAEFEFGFEAFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF@D
+@M01368:8:000000000-A3GHV:1:1104:12288:20635/1
+CACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGCCGCAGCATCTGTCTTTGATTCCTGCCT
++
+ABA?AFBAB2>AFGGGGFFGD5GGHGFFHGHEGGGGHHHHFFHH5FHGHHHFFHEFHHHHHHGGHHHHHGFHGGHGGGGFHGGGFBHHHFGEGHHHHGHGGGGECEHHFHHGHHFFHFGGGHHHEGHDGHHGHGHFHHHECGCBCHHGFHHFHD1GFHEFHEF?GDCFFEFE0A@;@>BD/9BFBBBBFDFFFF99D=?>DDBFF-AFFEBB9BBEFEFAFFF//-@---;;FBBFBFB///;99999BA9
+@M01368:8:000000000-A3GHV:1:1104:13832:4398/1
+CACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGACAAAAAAAAACACACAACAACCAACACCCAGTAGACTAGTGCGTC
++
+AAABABCAFFFFGGGGGGGGGGHFHHHHHHHHHGFFHHGGHGGGGGHHHHHHHHHHFHHHHGHHHHHGGHGHGGHGGGGGGGHGFFGGGGDGGHHHHGGGGFGGGGGCFGGEGCDGGGGGGGGGGGGEGF?;BFFFFFFFFFFFFFFFFFF:FFFFFFFFFFFFFFFFFFFFFFF/FFFFFFC.;BFEAFFFFF;@FFBFFFFEF?/FFFFE----:...:...9....9.9...:.9//9////;/9-.-
+@M01368:8:000000000-A3GHV:1:1104:23670:4161/1
+ATTCAATTGTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCC
++
+AAAABFFFFFFFGGGGGGGCGBBGGHHHHHHHHHGHHHHHHHHHHFGGHHHHHHGGFHHHHHHHGGGGGFHHHGHHHHHGHHHHGHHGGGHGGGGHHHHHGHHHHHHEGGGFHHHGFFDGEGHGHFHGHHGEGGGHHBGHGGHGHGGGGG/@FCDFDGFHGGGDFFHFGFFGGGGGHHHHGGGGGGGEGCDG?GGBFFFEE00BFFGABBBAFGGGEGEA.9FFF/./;BFBF./AAF/BFFBBF/F/BFB
+@M01368:8:000000000-A3GHV:1:1104:24927:22253/1
+AGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTAT
++
+AAA?AFFF3DFFFGGBGFF3EAEEEHFHHFHHHGHHHHDGHHGAEFGHHHGFCHHGHHHBGHHHAEGGHGGFHFBFHHHHHHHHHHFHH1EEHEEHH1FFDEEFCGHBGHHFHEHHHHHH1FCGHHHHEEFGEEGFFCHHH11>GHHF/FG2DGGCGAGGHGGGG@@@BEFFF?@@@FFEFFFFFF?@@FB@BB@FFFE=;==---A9EFBBB/;E;A9B/B/FFFEF/B///;/;9/A/;/9BFFFBFBB
+@M01368:8:000000000-A3GHV:1:1104:4705:7727/1
+CTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGG
++
+BBBBBFFBFFFFGGGGGGGGGGHHHGHHHGHHHHH6GHHHHFFGGGHHHHHHHHHHHHHHHGGFGGGEGGGHHHHHHHHHHGHE3FGGGGHHHHHFHHHHHHHHHHHHGGGGGHHFHFCGFHHGGGGGGGHHGGGGHHGGGGGGHHHHGGGADCHHHHGDGGGGGGGGC@DGFHEHHHHHHGHHHHGFGDEGFGFFGGGGCFGBEGFGGGFG;C.BFFFFFFFBFBFFFF/F?.AFFF/BFFEFFFFFEFF
+@1:A:M01368:8:000000000-A3GHV:1:1104:7756:4776/1_PolyA:1
+GGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTG
++
+CCCCCCFFFFFFGGGGGGGEEFHHHHGHGHHHHHHGGHHHGGGGGGHHGHHHHHGHHGHHHGGFHHHHHHHHGHHHFHHGHHGFGGGGHHHHHHHHGHGHFFHFHHHHHHGGHGFGFHHHGHG?FGHHHHHHHHHHHHHHGHGHHGHGGCDGFFHHHHGHHHHHGHHHGFHGHFHGHGHGH/@CABFFFFFFFACAFF?BBFFBFD-@-.D>FFAF.F.:9---;AADFFFFFBEFFF:9FFFFBBFFFF
+@M01368:8:000000000-A3GHV:1:1105:11310:21761/1
+ATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTTCACTTT
++
+CCCCBFFFFFFFGGGGGGGGGGGHHHHHHHHHHHHGHHHHHGGGGGHHHHHGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHGHHHGHHHGHGHHGHHHHGGHGGG=FFGEHHHHHGHFGGHHGHHHHHFHHHHHHHGGHHHHHHHGHEHHGHHHHHGGGGF9AGE?DEGFFGGGGGGGGGGGGGGFFFF/9FFBFFFFFFFEFFFBFFFFFFFFFFFFEFFF0
+@M01368:8:000000000-A3GHV:1:1105:11578:14676/1
+ATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTC
++
+CDDDDFFFBFFCGGGGGGGGGGHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHFGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHHHHHHHHHHHHHGHHHHGGGGGGHGGHGHHHHHHH;CHHHHHHHHHHHHHHHGHGGGGFGGGFGGGGGGGGGGGGFGGGEGGFFFFFFFFFFFFFFFFFFFFFFFFF/FFFFFFFFFFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1105:13575:19255/1
+TTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGTTCCCGTGAGTGGTTAATAGGGTGATAGGCCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+AA1A1DFFFFFBGG3A111FFAEGDDBGFDHF00F01BBA00BFGEHFBFFA1FABB0FAE?CFHF1BGFHFB0011F121E//>>1F10>B?EFHGCC/?/BFG/EEGFFEE//BCFDE0?E@@B/?11</?//<@?/F<<<A-<FBGH0.00=G0<<C//./0;;GC....<C.=.00;;BB./:.900////.C000;0090;..//000;C/;;/B/9BA9A9-AEEFF?B---;B99//9/;A//9
+@M01368:8:000000000-A3GHV:1:1105:15502:11453/1
+GTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCTGTCTCTTATACACATCTC
++
+A3AAAFFFFFCFGGGGGGGGGGHHGHHHGHHHHHHHHHFGHHHHHGGGGHGHHHHHGFHHHHGHGGGHHGGHGGHHHHHHHHHHHHHHGGGGGFHGHHHGHHHHHGHHHHGGGGGGHGEGFECHEHGGGGGGHHHGADFHHGGGGHHHHH<ECGGGGHHHHGGGGGGGHGGGGGGHHHGHGHHGEHBFFFGFGEGGGGGEDEGF0C;;BFFFGGGBEFFE/FFFFFFFFFFFFFFEFFFFFFFFBFFFBFF
+@M01368:8:000000000-A3GHV:1:1105:16787:9771/1
+GTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGAT
++
+AABCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHHHHHHHGHHHHHHHHHHHHHGHHGGGGHIIHHHHHDHHHHHHHGHHHGGHGGHHHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHGGGHHHGGGGGGHHHGGGGHHGGGGGHHHHHGGGGGGHHGHGGGGGGGEEGEGFGHHHGGGGFFGGGGGGGGGGGGGGGEG?G;:EFFFFFFFFF:AEFFFFFFFFBFFFFFFFFFEFF/
+@2:A:M01368:8:000000000-A3GHV:1:1105:17564:15723/1_PolyA:2
+TATGCTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTG
++
+EDCCDFFCEEDCGGGGGGGGGGHHHHHGFGHGGHGGHHHHHHHHGHHEHHGGGGGHHHHHHHHHGHHHGHHHHGGGGGHHHHFFGHHHGGGGGGHHHGGGGGHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHFEHHHHHHHHHHGHHGHGGHGGGCGGGGHHH1FGGGFGGFGGGGGGGGGGEFGGGGGGGGGGGGGGGGGFFFFFFFFFFAEFFFFFFFFFFBBFBBFFFFFE1:BFF
+@M01368:8:000000000-A3GHV:1:1105:18108:12091/1
+TAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACAC
++
+CCCCCFBFFFFFGGGGGGGGGGHHHHHHHHHHHHHGGGGGGFHHHBFGHHHGGGGGGHHGGGGGHHGFGGHHHHHHGGGGGGHGHFGGGGGGDGEGEFGCHHHHHHHHHHGHHHHGEDHHHGGGCDGGGGFHFHGHHHGHHGHFGHHHFHHGFHHHFHHGGHFHFHHGB0CGHGFHCBGGGGEDEE9ADFEFFFGFBFGFFGGFFFFFGGFGFFFFFFFF/A?FEFFFFFEF-A.B//;BFFEF//BB///
+@1:A:M01368:8:000000000-A3GHV:1:1105:18331:16683/1_PolyA:1
+TCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATT
++
+BABA?DFFFFFFGGGGGGGGGGHHHHHHGHGHHGGGHHGHGGGGFFHHGHHHGHHHHHHH3FGHHGGGHGGHHHHFHHHFHGHHHGHHHHHHHHHHHHGHHHHGGCGGGHHGHHHHHHHHHHHHHFHHGHHGHGHEFGGGGABFFFGBEGGAFFFFFFFFFFFFFDDFF?DFFFFFFFFAEFFFFFFFFFFFFB;9FFFFFEFFFFFFFFFFFF?FFFFFFF/BFFFFFFFB.DABFFFFFFB.//:FB/
+@M01368:8:000000000-A3GHV:1:1105:20577:18421/1
+GGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCC
++
+ABB@3>AAFFFFFEAGGGFGGAA6FHDGGCGFHFFHFHFHHHHHGDDDFFFHGFFHGBEGEGHHHFFFHGEEAEGHHHHHFHHHFHGHFEDGGEGBEAGEFHHFFHHHHHHGGHHHGHHGBGHHFHHFGHHHHG?CG?AFHH1FHHHGHFHHHF?DGHFFHCGAGEFHGCBBBB?BFFF?B-B.9/BFFFFFB=-AD?..@FFFF@@-@@?AFD.FFFBBEEBD9/:FFFFFBB/:FF9BF/BF.BBFF/:
+@M01368:8:000000000-A3GHV:1:1105:21099:2895/1
+TAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTT
++
+CBCBBFFFFFFFGGGGGGGGGGGGGFHHHHFHGHHHHHHFHHHHFGFHHHHHHGHHHHHHGHHEHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHHHHHHHFHHHHGHGHHHGGHHHHHGGHFFGHGCGGGHGHHGHHHFGHHFHH/FGGGHFGFEGGCFCCD;B@DFFFFFFFFFFFFFFFFFFFFFFFFF;F.BEFADFFFF.AEFFFFFFE;D.;:B00099:09BFBFFBFF.0:000BFFBF0
+@M01368:8:000000000-A3GHV:1:1105:26469:19245/1
+TTATGATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCAAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATG
++
+BAAAAFFFBFFFGGGGGGFFGGHHHHHHHHHHHHGGHHGHHHGGHHHHHHHHHHHDEGGHGHHHHHGEDHFHGFHGGHHGGHGGEHHHGHHGHHGHHHGGEGGGHGHGHHHHHHGHHHHGHGGGGGHFHGGGGHHGGGGCDGHHHGD<EHHGGGGGHHGHH?EDCCDHHHHDGFFGGGHGGFCGGHHHHFG.CFGGGGGGGGGGGBFGDEG.AFFG;AFFFFEB?/A9BBBFFFFFFF/9FFFFBDEFFFF
+@M01368:8:000000000-A3GHV:1:1105:7169:17145/1
+AACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGT
++
+CCCCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHBHHHHHHHGGHGGHHHHHHFHHHHHHHHHHHHHHHHHHHHGHHHHHGGGGCHHHHHHHHGHHHHHHHFHHHHHGHGHGHHGGGGGFGGHHGGGGGGGGGGGGEGGFGGGFFFFFFFFFFFFFFFFFFFFFFFFFFFDFFFFFFFFFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFFFFFFFF-9@DDBFFFFFFFFBBFFF0
+@M01368:8:000000000-A3GHV:1:1106:15481:16176/1
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTT
++
+ABBBBFFFFFFFGGGGGGGGGGHHGHGHHHGHHHFGHGFGHFEHGGHGGHHHGHHHHFGHGGFGFFHHFHHHHEGHFHHHHHFGGGGGHGGGHGFHGHGGGGGGHHHGGGGHHGGGGHHHGGHGGGGGGHHHHGGGGGCFHGGGCDGHGHHHFHEHHHHHHHHHEEFHHGG:C:?0<EFGBFGGGGGFE.BFGEFFFGFFGGGGGGFDEF/FFGFFFFFFF;BBFA;.:EFFE:AAFEF.BFFFFF;9FF.
+@M01368:8:000000000-A3GHV:1:1106:17389:18671/1
+CCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGGCTTTGATTC
++
+3>>A@FFFFFFFGGGFEECFGGFFB5GBHH5DFH5GBEEAEFHFHHF3F3GHFHHHEF3GAEHBGFHFFEFFHHHHFFB31FGGEGFHGEHHHHHHHHHHHHHHHHHEEEEGHHHFFF3GF3FGF44BBGEHHHHGG2B/BGGHE</ECDFHHBF1DGBFBFGFH<1GHGDGGFDFE0/<--;-9./BBED;BFBD/BF9BFFFDBFDADD;FFF?->;B=.9.;.BBFFF..;A;/B/;B//;;//BBF/
+@2:A:M01368:8:000000000-A3GHV:1:1106:22927:3863/1_PolyA:2
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGACTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACT
++
+A>ABAFA?D@AFGGGGFGGGFGFHHHFFH4BCBGHHHHGFFF3G5BF3322EEAFHHHHHHAB5GHFHEHFHHH3BEEHFGF5@13FDF3GDGFHHFGHHHGHHHGFGGHHFCG//?/EGHHHG3F4BFFGHHHEDGFHHB/B/?FBF<@-9?BDEFFF?B--?DFFFB9FA>B;A.BFDB?AB.--@;-.FFAEFFFF9AE;DDFFFFB/9BFFFFFFFB:BF/BB/BFF//FFF-=--.99=--.9/
+@1:A:M01368:8:000000000-A3GHV:1:1106:23625:4236/1_PolyA:1
+TAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATT
++
+@?AAAFFBFBFFFGGFGFGGGEFCGGHHHHFGHGHFHGHHHHGGFGGFGHHGHGHHHHGHGFFHHGGGGGHHHHHHHHHBFHHEFHHHHHHGF?FAGHGFHHHGDGFHHGGGHGHFHHHGHHHGHHFHHGFFGFHHHGHHHHFFHHHHH/FGHHHHGHGHG<C???B=@ABBFEF@=-AFFFFFFBFAFFDFFFFA?AFFCFFABEFFFFFFFFF?FFFDFFBFF;FFEFFEFFFFFFFAF///9FF/BB
+@1:A:M01368:8:000000000-A3GHV:1:1106:26031:14826/1_PolyA:1
+GATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATATCGTATGCCGTCTTCTGCTTG
++
+ABBAAFFF@FFFGGGGGGGGGGHHHHHHGHHHHHGGGGGHHHHHHHHGHGHHHHHHHHHHHGHGHFHFGE?CGDGGHHGGGGGGGHHHHGHGGGGGGFGGGHGHGGGGGGGGGGGGGGGGGGDGAFFGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFB/9FFBFFFFFFFFFFFFFD@D=BEFFF;FDDB////B=CF-.;BAFFFFFF;;BFE/BFFFFB
+@1:A:M01368:8:000000000-A3GHV:1:1106:27607:15990/1_PolyA:1
+GACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGACTTCTGCTTGAAAAAAAAAAACTACAACCCACGGACGC
++
+BBBBBFFFFFFFGGGGGGGGGGGGHHHGGGGGGHHHGGGGGFCEGGHHHGHHGGGEGGHHHAFGGGGGGAFG//EGHHHHCGEHHHHEEHHFHGHFHHGGEF/FGGC?FDFH2DHHFFGGFGHHHHGGHHFGHHGHGHHGFHDHBGBBGHHFHHGGCCDC<=D<DGHHC;CGFCCFBECDG?FGGA-;EB9FBGFFBBF>DFFFE?FFF/--;;9/:BFFFBA///9----;B.//////;...---9--
+@M01368:8:000000000-A3GHV:1:1106:6455:17124/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+BBBAAFABDBBFGGGGGGGGGGHHHGHHGHHHHHHHHHGHHGHHGHHHGHGGGEGHHHHHHHHHHHHHGHHHGHHHGGHGGHHHHHHHHHHHHHHHHHHGHHHHHHHHGHHHHHGGCFEHHHGFHHHHGHHFFH?GGHHHHGHGHGHHCFGGGGGGGFFFFFFFFFFFFFFFFFFFFADFA?.FEFAFFFEFFFFFFFFFFFFDABFBBFFFFFFFFEFFBFFFFFFFFFFF/FFBFFFFFFADE>BFFF9
+@1:A:M01368:8:000000000-A3GHV:1:1107:14451:26748/1_PolyA:1
+GTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTG
++
+BABBBFFDABBBGGGGGGGGGGHGHHHHGAGHGGGGGHHHHHHHHGHHHHHGGGGGGFFHHHHHHHHHFHHHHHGGGGCHFHH3FEHHGCGGGDGHHHGFGGHHGGGGHHHHHHG/DGGGHHHHGGGGGCCHGG?CGG1GHHGHHHHBGHHHFHHGHHHHGGADAD00ECEGHEFHHFFAEFFFFFGGFBFBFFFGFFG.;B/99;BCFGGGGEFFFFFFEDA./:ADEB?FBFFFF;FFEBFBFFB./9
+@1:A:M01368:8:000000000-A3GHV:1:1107:18714:24788/1_PolyA:1
+GTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTG
++
+BBBCCFFFDEDEGGGGGGGGGGHHHHHHGGHHGGHGGHHHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHCFGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHGHHHHHHHHHHHGHHHHGGEGEGCCEGGHHHHHHG:CAFFGGGGGGBFEFGGGGHGAFFGGFGGGGGGGEFFFFFFFFFEF/EDDFFFFFFFFFBFFFFFBBFFBBF
+@M01368:8:000000000-A3GHV:1:1107:21355:8333/1
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATG
++
+ABCBBFFFFFAFGGGGGGGGGGHHHHHHHHFHHHHHGGGGGHHHHHHFHHHGHHHHHHHGGGGGHHHHFFGHGHGGGGGGGHGGEGGGHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHGHHHFHHHHHHHHGHFFHHHHGGHGEGHHGHGFHHFHGHCEFHEGHGHHHGHHHGGGGGGCFFFFBFGGFGGGGFBG?FDGGGEGFFFFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBFF.AA/9
+@M01368:8:000000000-A3GHV:1:1107:22864:15712/1
+AATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATG
++
+BBBBBFBBFFFFGGGGCEGGGGHGHHDGFHHHHHHHHHHHHHCHHGHFGBGDFGE?GHHGHFBHHFHHHHHHHHHGHFGFGHGHHGGC@DCFGHHGGGGGGGHHHHHHGGGGGFGGGGFFGGGGFADGFEFFFFFFFFFFF9;FFFF/BFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFEAECDFFFFFFFFFBFFFFFFFFFFFFFFEFBFBFFF/FFFDF-;-9;E@>-9DFFF/FFBF;-.:;.9A//
+@M01368:8:000000000-A3GHV:1:1107:24817:14233/1
+CTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACAT
++
+3AABABFFBFFFGCFGGGGGGGHHHFGCFGGGFFGHHCGHHHGHGHGHBFFHHHEDGGFGFGHHFFFHGGEGHFHHGHFHGFFHHHFGHHHFHACECEHHHBGFHGFHHHFHHF4GFHFHFHEHGGE/EG:A-CFGGFGADGGGGFGGGGDAAAADFA.-AFFECFDAAFFFFEFFFFBFF;D;BFFFB/;BFFFFFFFFFFFFFFBFFBF/;//;BFFFF?FFFFFFEDAFFFFFBF//:BFBACF--9/
+@M01368:8:000000000-A3GHV:1:1107:24830:14440/1
+AACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACC
++
+ABBBA@FFFFBBGGGGGGGGGGHGHHGHHGHHHGGHHHHHGHGHHGDHHHHHHAGGGGFHHGHHHHHHGHHHHHHHHHHHEGAFGFHFHHHHGEGHHHHHHHHHHHHHHHHHGGHHHGEFEGGHHGHHHHHGGHGFHH/?GHHHHGFGHGFHCGGBBDAFFFEFFFFFFFFFFFFFF=CDDADDFFFFEF=BFFFEFFFBFFFFEEBF./:FFFFFFFFFFFFFFFFFFFEFFFFFFFFFFF/BFBEFFC-
+@M01368:8:000000000-A3GHV:1:1107:26478:23602/1
+GCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATCTGTCTCTTATACACCTCTC
++
+1AAAAF1B13BBBEGGGFGGGGGGHHDB1BGFHHHFGFGGG0F00BGBGFGGF1GBGB1BGCGAEE/FGFHGHFHHHHHBFF1B0FGGF//F//FGFGFFF/1@B1DFHHHGGEFEDHFDFAFF0B//</ECCC>1FDD1GFFHHDF?1BD>GF/GCAC0C@?@-;99BBB->@--;-B//99B--9-BF=A--A-:A----9AA9AFBFBBB?E@BBFFFFFFFBFFFFFBFFFBBFFF//B/////-;9
+@M01368:8:000000000-A3GHV:1:1108:11059:23181/1
+GTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGAT
++
+CCCCCFFFFFFFGGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHHHHHHHHGHHGGGGHIIIHHHHHHHGHHHHGHHHGGHGGHHHHHHHHHHHHHHGGGGGHHGHHHHHHHHHHHHHHHGGGGGHHHHHFGHHHGGGGGGHHHGGGGGHGGGGHHHHHHGGGGGGHGGHEFGGGGGHGGG-ECHHHGGGGGGGGGFGFFGGGGFGGGCF?EFGG0;BFFFFB?9AAFFFFFFBF;BBFFBFFFFE?F/
+@M01368:8:000000000-A3GHV:1:1108:12233:13498/1
+TAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCCTGTCTCTTATACAC
++
+BCCBAFFBCCCCGGGGGGGGGGHHHHGGGGGHHHHHHGHGHBGFHHHHHGGGGGHHGGBFGHHGGGGGGGHHHGGGGHHGGGFHHHHHHGGGGGGHGHHGGGGGGGGGGGGGGHHHHFHHHGHGHHHHHHGHGHHGGFGGGDFFGGHHHGHGH/<GHHFGBGFHFBGHHHGHHGEFHFHFGBF0BFGGGFGGGGGEFFF;A?EEG?CFFFFF0:BEFFFFFBFFFFFF0FFEFF?EFFFF0BFFFFBBB00
+@1:A:M01368:8:000000000-A3GHV:1:1108:14328:14751/1_PolyA:1
+ATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATAC
++
+BCCCBFFFFFFFGGGGGGGGGGHHHHHHHGHGHHHHHGGGGGFHHHFFDGHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHGHGGGGGGGGGGGCFGHHHHHHHHHHHHHHHHHGHHHHGGGDGGFGGFGGHHHHHH>FHHHFHGHGHHGHHHGHHBA<CGFHHHHHHHHHHGFHHGDDEGCEGGGGEEFBFGGGGFGGGB0CFF:FFFFFBBFFFFBFEFA.BFFFEFFFBF/BF/FFEFFBFFF
+@M01368:8:000000000-A3GHV:1:1108:16350:22621/1
+TTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+AAAACFFFFFFFGGGFGGGGGGHHHHHHGBGGGFGGGHFGGGGGHHHHHGGHHHHFHGGGGGGHHGFHHHHHGEFHHFFHHGFCEFHHHGFF?GHHEE@ECFHHEGGGGBFFEGGGHFDHHGFG/BFEHHFCDGGGCDEGGGCGFFFHHHFEGHFHHHHGHHDGHHHGGHDED0CE;CFFFFBFF/;CBFFFGG0/FFF0B0:BB?.;BFF0FGFBFFFFFEFE;ADED.;BE.99FAFFFFFFF/;EFF/
+@1:A:M01368:8:000000000-A3GHV:1:1108:21791:23272/1_PolyA:1
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTT
++
+3ABBBFFFFF@FGGGGGGGCGGGHHHHHHHHGHHACGDAGFEEHGGHHGHHHHHHHHHHHGGGGGGHHHHGFHFGHGFDDGFFFGGFGHHFF?FEGHHGGGGGGHHHGFFDHHFGG?HEFGHHGGGDDCGFFC?ECCFGDEFGGGGGGFHHHHHHHEFHFCGHHGEGGGGD.:.A;CECAFFFFBFF/;EFFBFFBFB;;BFFFFBBAA./BFFEBB//BFFFFFFFDFFFEEFEFFFBFBFBBFFFFF.
+@M01368:8:000000000-A3GHV:1:1108:23314:26089/1
+ATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTG
++
+BBBBBFFF?FFAGFBFGGEGGGGHGHHFHHHGHHGFGGFHHHHHHHHFHHFHHGHHHGGGGGHHHHFFEHHHGGGGGGHFHGEEGF3FEFGHHHHHFFDEEEEHHHGEEGGGGGHFGGDADGFFFFFHHFGHHHFGBHGHHGBCEHDEDDGADCFFHHHGG/:GCCCGHFGHFFGG0CGFGF.FB/9;BFBB0FFBFG0A-..;C:E/.A9.FFFFFFFF9BFFFFFFBFBBB./:BFFF/F;AA?F////
+@M01368:8:000000000-A3GHV:1:1108:25084:18127/1
+TTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGAGATAGACCTGTGATCCATCGTGATGTCT
++
+CCBBCFFFFFFFGGGGGGGGGGHHHHHGHHHHGFGGFHHHHGHHGGFHEHHHCGGGHBHHHHHHFHHGHHHHGGHHGGHGGGHHHEFHHHHEHGHGGGCFHFHHHHHHHHHHHGHEFGDEGGGHFHHCGGHHGGGGGFGHHGGEGDFHEGG/?GFHGHDGGGGGHHHHADFGGGGGEGCGGGEFGHHFEBFFGGG?GGGGEGGFEFAA?.0:A0;BFFFBFF/;9BFFFFEFF9FBFFB/F/.;FFFF/BB
+@2:A:M01368:8:000000000-A3GHV:1:1108:7626:10048/1_PolyA:2
+ATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTG
++
+CCCCCFFFFFFFGGGGGGGGGGGHHHHEFEFHHGGGGGGHHHGEF?GGGGGGHHHHHHGGGEGEHHHHGGGGGGGGGGGGGGHHHHHHHHHHHHFFCGHGHHHHGG/BFGDGG2FFHFHGHH0FHFGFHHHHFFHHHHHHHGG<FHHHFGHHGGGGFHHHGGGGGGHGGHGGGHHHHHHFGGGGGGGFFFGGFGGBFGGGGGGGGGGGFGFFFCFFDFFFFFFFFF;./;AAAFFFFFFAFABBFFFB/
+@M01368:8:000000000-A3GHV:1:1109:11270:12255/1
+AATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAGGTAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTT
++
+CCCCCFFFFFFFGGGGGGGGGGGGHHHHFFFHHHGGGFGGFFHGEGCHHGGGGHHHHHHGGGGGGHHGHGGGGGGGGGCEGFCHHHHHGFHFHHHHGFHHGGFHGGGFD/EFGEFFDGFHHGEFCEHFFGHHHGHHHHHHHHHGCGHHHGGFGHHHHGHEHHCFFADGHHHD?CG.CGHBCBFBFFGGFFFGFFFFF.CFBFBCFFFFGFFFFFGGGFFFFFDFAFFFFFF-@DBFFFFBFD---.;BAA.
+@M01368:8:000000000-A3GHV:1:1109:19224:11655/1
+AAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGCATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCTGTCTCTTATACACATCTCCGAGCC
++
+BBB@A4FFFBBBGGGGGGGGGGHHHHHHHHFHHHHGFGHGGGFFAGFHHHFHHHGHHHHHHHHHHHFHGGHGHHGCFFGHHHGHHHGHHFHGGH3BFFGHHGHGEFFH/EG@-CFGGCC@-;BD?FGGGGGG??FGDAGDFFFFEFF@BAAFEFFBFFFFF?FD9BBFFFF/FFFFBFFFFFFF?FFBFFFF/FBBFFBFFFE?F;@B//AFFFFFFFFF//;BFFEF.BFFFB/;F/99/FBFFBDCF;B
+@M01368:8:000000000-A3GHV:1:1109:21978:9490/1
+GGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCAGTT
++
+?A3AA?DFFFFFGGGGGGGFFGHFGCEGGFHHHHHHHHHGHCBGFEGGHHDEGAFGHGHFGDGBCGHHHHHFHHGHHHHHHHGHHHH1E?EGGGHHHHFGFHFHHHHHEDHHGHH@GGHGHHCGG?CFGFGGGGGFGB.BFGGFFGGFFFBDDBFFFFFF9-;DEFFDFBFFBB.EFF;BFBFFFFFFFFFFFFFFFFFFFFFFFFF/B9/FFFFFFFAFFFF--99AFFFFFFFA;;;FF..9//;/;;/
+@1:A:M01368:8:000000000-A3GHV:1:1109:22910:4079/1_PolyA:1
+TAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTCCACTTTAGCT
++
+CCCCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHHHHGGGGGHHHHGGEHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGFHHHGGGGGGGHGGGGGGHHHHHHHHHHHHHHHHHGGHHHGGHGGGHHGHGHHHHHHHGFHHHHHHHHHHHHHHHHHHGGHHHHHHHHHHGHHHHHHGGGGGGGGGGGGGGGGGGGGFFGGGGGGGGGGGFFFFFFFFFFFFFFFFFFFCCDFFFFFFF0BFFFFFFF
+@M01368:8:000000000-A3GHV:1:1109:24217:19077/1
+AAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGCCTTTGATTCCTGCCTCATCCTATTACTGTC
++
+>AAA3BDFFFFDGBFFEEGGGGHHGHFHHCFHGHGHHHGF3BFGFHGFEFHFHGH3EGFC1EEGBFGBHFGGFFHHHGHFHGHHGHGGHCEHEBCFF3ED3@GH4FDEG12FFHFFHG/G3FGA/@EFEFCG33FFGBBGHFHH/?BFBGFGFAGC2C/@-;@-;BFFEFADF?DFFFFFF?;AFFA;AD;..FEFFA--;9;D.9BFFBE?;.;///://///99//BB/9;F./B//BBFB9////99/
+@M01368:8:000000000-A3GHV:1:1109:25237:11722/1
+CCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATATCGTATGCCGT
++
+AABBBFFFFFBBF5BGGFGABGHGGAEFGFHHHHFHCHFHHBFGGGEHBGGHFFFFGFAEF5FHH?EGGF5AEG3?EBFHD?C/EFHFFEGEE?CFGGGHHFHB3EEFG?EEGHCFGGGGGGGEC<CDFHHHHHE.FD11FFAGBGD.DGHEA<.<<0<EHAHCFHHF./;CC0GFH0::0CFGG0FBFD;9/90BFF0CBBFGB09;B:0;CFF0.-;@AFEEF--;AFFBF/99D-;.//.../9;B-.
+@M01368:8:000000000-A3GHV:1:1109:27103:7153/1
+GTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGCTGTCTC
++
+33>A?FFFDFBFGCG4EGFG??GACFGGHFHCFHCHBECDEFCEGHHHHHFFGGF3AFFHHFGEGCGHHGEHGFGHHEGG?EFHHH?EGGHHGGGGHHHHHHEGGGGGHFHHGFDDGGACFCC@?/FDDGHHHGHEFFHHH0FDHHFFEDCD.<GGEHGF0CHHHF/CAGC000CCGFHFGFGFFG?:CB990;F09;FB0BBGGGGGG?;A9EBDEFA///;FF/:F?BFBBFFBFFFF///;/9B;///
+@M01368:8:000000000-A3GHV:1:1109:8763:7859/1
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGCTTTATGC
++
+BABAADFFFFFFGGGGGGGGFBGFGHHFBHHHHGGHHGGEHGDHHHFGHEHHHHGHHGGGGAGHHFBHHGHFHHHHHHHHGGGCEFGFFFFEHHH?FFG1FFHHFEGGGHGFEEHHHHHGGGFGGGHHHHGGGGG/C/FG-<A<GFHHFFCGHHFHGE0<<CGHHHGCHG.CCCCCE00BBFGFFG.BB0FFBFBCF0;CBFFFEEGBBBFFBF/FFF9BF/9BAFFD9AFEDAA.A/BFFFFFFFFFEB/
+@M01368:8:000000000-A3GHV:1:1110:12808:18367/1
+AATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCCTG
++
+BBBBBFFFFBBFGGGGGGGGFGFGHHGGGGGHHHHHHHHGFHHGEGGGHHGFGHEEGGHHHHGHHGFFHHGGGGGHHHHGHGHGHHHFGGFHHGGGGGHHFFFGGHHHE?@EGGHFHEGGGHHGGGGHGEFHHGD?/>CFHHGDFGGGGGEFGC?EGHHHB0CGHHGCGHHHHBEHGHH.::ACA;FECFGGGGGFFFEFGGGGGGGFFBBBFGBFFFEFFFFBFFFFFFBBFBFFB9..AF?FFFFFFF9
+@M01368:8:000000000-A3GHV:1:1110:14751:26540/1
+TAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACTGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGTTGTGCACGCGATAGCATTGCGCGACGCTGGCGCCGGCGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTG
++
+AAA?1CFFFFADGEEGFGB1112DGDGHGFGHHCG/ECEBGGHDFGHHFHGHEB1BCGFFE2EGHHGHFFFHHBFFHEFCGGHHFHHHHH111BFFHGHEHBEHGGECEFHGFHFGGDBBGHHBHHHH0GH22FGHGFFFH1BFCG0F@FGG11@GDHFG1D/1FGFHH/FCG.>0><-<@CCFFG.CC-@C?C9FFF0C---;------;9----9-9@-AAFF9B9---9-/;B9BF/9BB//B/;///
+@M01368:8:000000000-A3GHV:1:1110:15519:10008/1
+CTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACC
++
+BBBBBFFFFFFFGGGGGGCBGGE?GGGHHHHHGHHBEGGHHGGGGGHHHHHHHHHHHGGHHHHGFGGGGHGHGCFGHHHGGGCGGHGHGGGGGHFGGGHHHHHHGCEFGGHHHHGGGGGGGHGG/CEGHHHHGFHHHGFHHGFFHGHGHFGGEGFDDGGBCGHHGFHH/CHHHHGHGHF0CFGGGGGGGFFFFFBFFFFFFGFFGGF?DGEDEEFEFFFF?FFFFFFFFFFFFFFFBFFF.BFFFBFBBA;
+@M01368:8:000000000-A3GHV:1:1110:16559:7507/1
+CATTCAATTGTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAACTGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATC
++
+ABBBAFFFFFFFFGGGGGGGFGGGGAGHHGCHHGHHHHHHHHHHHGHHGHHHHHHHHHHHHHHHHFGGGHHHHHHHHBDHHHHHGGHFEEGHGGHHHHHHHGHHHEHFGGGGGGHHHF33FGHHG3GDDGH//EEGHHFFBF?GHHFCC@DGFCGGB?DGHAFGGHHGFH0E??<@DGHGGCFGGF?DGGGFFGGGGGGGG.C/0BBF?FBBEGG0FFF.AA9;B9/E////99;;:.//:FFFFBBF//9
+@M01368:8:000000000-A3GHV:1:1110:16700:6843/1
+AAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCTGTCTCTTATACACATCTCCGAGCC
++
+BBBBBFFFFFFFGGGGGGGGGGHHHHGHHHHHHHHHHHHGGGGGHHHHHGGHGHGGGGGGHHHGFFGHHGGGGHHHHHHCGG@FGHFHFEGGGGGGHGGGGDGHHHHHHHHHHHHHHGHHGHGHHGGGGGCGHEHGHHHFHHHFF.DGHHHHHHGHHHHHHGFGHGCGHGHHHHHHHHGHHHCD?:A::FCDGEGFGFFBFGBFGGGF00CBFFFF/BFBFFFFAE.FBBFBFFFFB/BFFBFFF/ADCAD
+@M01368:8:000000000-A3GHV:1:1110:18014:7856/1
+ATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGCAAAAAAAAAATAG
++
+AABBBFFFFFFFCGGGCGGGGGGHHHHHGFHHHHHHGHHHGGGGGFHHGHFGGHHHGGFGGGHHGGGGGHHGGGGHGGHHHGGGGGGHHGHGDGGGGGGGGB/A<GFHFHHHGHBBGFEGGGGHFFFEF/EEGGHGGFEHFHHBA.<ADFFHFHB/CCGHFEFHHGHGEFFGGGGGFFFGGFGFFBFFGGBFGG??DGG?@9-ADFFFFB/@BD;./BFE?BFE/>99FE//BBFFF.9/FF?DA=@9./9
+@M01368:8:000000000-A3GHV:1:1110:23303:11846/1
+ACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGTGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTC
++
+3ABB?FAB?DAAGGGFBGGBB5AFFFGFHHGGGEGHHHFHHF3EGFHHHHEFHHGGHHHGH3EFHHHHHBDGHHE?ECHGHGHHHHHHFHHHGHHHHHHHGGHGGFHHHFHHGFFHHFEGFHHHHHHEHHFDAGHHHH/BDDFGGH1FDBGHHHHHHHCGHHHFH?0CGCF>CC=@--AFBFFB?=BFDFFF//FDB;-9A-AD-.A.A=?-9-:B/AEB/BFF.A;DDFFFBBFFFF/BBFFFFBFF9B;
+@1:A:M01368:8:000000000-A3GHV:1:1111:13195:14562/1_PolyA:1
+ATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACACATCTCCGAGCCCACGAG
++
+ABAAAFFFFFFFGGGGGGGGGGGHHGG4FDFGFGGCGGGHGHG?EGHEGFFDHFHHHHGGFE@EHHGEEEGFCCEFFGFG/EHHHHHBFBGGHFHFHEHGHEFGGGED/EFDEFFEHHBGHHCFFFDFGGHHGFFFHHHHGFG>0<0DGGFHBGHFBDFGHGFFGGAGHHGCGBHFFHHHFFFBFGGGGF/:FFFCB9F9FF0FEFE?FF0BED-D.//BF9//BBFF/BFFFEFFFFED-DCFF?.:BF
+@M01368:8:000000000-A3GHV:1:1111:14287:20817/1
+GCCAACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTCATCGCACCTACGTTCACTATTACAGGCGAACATACTTATTAAAGTGTGTTAATTAAT
++
+>>A3>AAAACFFFGFGFGGGGGHGHHHHHHHGGGGGHGHFFCGHHGBGHFHHHHAGHHHHEHHAGFFEHEAE?GHHHHEGFFFDGHGHBFFHFHHHGHGHGHBECG@@@EHGGEGCGGGGFFGGGG?BGGGGGG.-C.FEDCFFFEFFFAF/99BEFA.:9BFB/9FFFEFFFFFFEFFF/FBBFFFFFFFFFFFB//;.@@//;DFFFF//BBFFFBF;A;DF=>B//;9B//B/;/;9//9//;B/:B9
+@M01368:8:000000000-A3GHV:1:1111:23624:14516/1
+GTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGGGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAG
++
+3>3AAFFFFFAFGGGGGGGGBGHHHHHHGGHGGHEHGHADFHHHHEGGGHBGHFFHHEHHGHFHGG5FBEEGEGHHHGHHHEFDGHHFFGFGGHHGHHHGHBHGHFHFHHGGGGFCFBGFGE?GFBECEGDGHEHGDGCGHGC/DF@GHGFFCGGGGFFFFDD?@C@GFEC?-ADHFFHBGHFBHFG0CC//.;B0/CA.;AA.;@.AB/9BB/A/.AFFFE/BFFF///9B/FBDE9/;99/B/BFFEF/
+@M01368:8:000000000-A3GHV:1:1111:7437:24508/1
+ACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTGTCTCTTATACACATCTCCGAGCCCACGAG
++
+CBCCDCFFFFFFGGGGGGGGGGGGGGHHHHHHHHHHHHHHHHGGGFFEHGGHHHHHHHHHHHGHHGGGGGHHHHHHFHHHHGHHHHGHGGGGGHHHHHGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHGHHGGGGGGGHGGGGGCGHHHHGHHGHHHHHHHEDHHGHGGGGGD;BEGGGFFGGGGC:CFGGGGGGGGGFGGGFFFGFFFFF;FFF;BFFFFFFFFFFFB:FFFFD=CAEEEF>-
+@M01368:8:000000000-A3GHV:1:1111:8665:25542/1
+TCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTGTCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCG
++
+AA3AAFFFFFFFGGGFGFFGGGGHGH4AGGGFHHCGEE2FGHHHHHHHHHHGFHGF53FHEGGFAF5CFHHGGFGHFHHGGHHHCHHHHHHHFHHGH?EEEG1FFFEHHFHFGGHHGG?F4FBGHGHCHEF0//-9--;0CFGG?@BGDGFFFFEFBBBDA?FFBFFFF=B;-9.AA9EFFFF/;9BD.//;9/9/B:/:BFBFFBFFF/B:BFF//;/B/FFFBFF.A-BFFFBA/F//BFFFBF/;/A-
+@1:A:M01368:8:000000000-A3GHV:1:1111:9655:13916/1_PolyA:1
+GGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGCGGTGTCCACGCAATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTG
++
+1>>1AAFFFFFBGGFE1EEEEGGHGHHH2FGHHHFGFGHGCFGGGEFHGGEGGHHHHGHEFBFEGHHHGHHBEHHHHGHGFHHHGGGGHHEGGGGHHHGFHGHHHH1FHHG?G/AGF1GBFGEFFHF2FDD0FG<GDHBFDGFFCGH//B//?0GFFGFGGHHHFHFB.=1FDFB?FGH.C/.-:::CH0;CAB@-.;0CGFFFGG--9.A@GB>--99@=---AAABA-BF/B?A@F-9BBFF//BB/9
+@M01368:8:000000000-A3GHV:1:1112:10272:7828/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTT
++
+AAABABBBBBBFGGGGGGGGGGHGHHGHGHHHHHHHHHGHHHGGHDGHHHGGGGHHHHHHHHHHHHHHHFHGHHHHGGHGGHHHFHHHHHCGHFFHHHHHHHHHHHHHGHGEFGAEEEEHHGHHGHGHHHHHHHGHHHHHHGHGHFFBC/BA?BGGGFFFFFFFFFFFFFFFC-@DDFFFFFFFEFAFFFFFFBFBFFFFFFFFFFFFFFFFBFF->@FFFFFFFFFFBFBFAD--.99;A?////:.9A.
+@M01368:8:000000000-A3GHV:1:1112:9832:16531/1
+CTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGGGCTGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCTTGAAGTAGGAACC
++
+AABABFFFFFFFF4GGGGEBGEFGHGGHGHGHHHGGHFBGFGGGGGHHEFHGEHFHFHEHHHHHGCGGGHFHHCFGHE@1EEEFFGB?EEEEHBGGGCHHGHHBEE@>EAHHFAEBDGGGCEFF?CEGFFHHHHHFHHHFHGHCGCAHHF<..C.D=0CD.GFHHHG.CAGHC:CHB0GGGFFB0:CFA.A-;9.;000CBBFFBFGA.9AA;A;EDDE.ABBFFFF9;BEFFF/BF//9/B//9:B//..
+@1:A:M01368:8:000000000-A3GHV:1:1112:9832:6701/1_PolyA:1
+CGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGG
++
+AABBBBFFFFFFGGGFGGGGGGHHHGGHGGHHHHHHHHHHHGHHGGGGGHHHHHHHHHHHHHHHHHHGGCGDHHHHFGGHHHGGGGGFGGHGGGGHHGGGGHHHHHHGGGGGGHHGGGGDGGFGHGGFCDCHHHHGHHHHGHHFAGFGGEHFGEG.C<EGCECEFCFFHBGHE:GHHGFF0FFFB0CFGGGGAGFFF0;;FFGGGFFGFFCDD.DEFBEDD?9FFFFFFFFFFFFFFF/B./FB///;BF
+@M01368:8:000000000-A3GHV:1:1113:13532:8618/1
+GGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGCTACAGTTCACTTTAGCTACCTCCAAGTGTTATG
++
+AA?AAFFFFFFFGGGGGFBFGGGGGGH5GHFEDHHGGGGCGFBGH?AEEHFFEEGHGHHHHGGG?0EHGHHGGGGGC?GEE/EE?GHHHGBHFHHHHHHGHHGHHHGGGCG/A@<FGGHHHHHHHFF/GFDGHHHHHHGFFFGHGGHABGHFHHHHHFHEGDGHGDDEEHHBEDDEGFGHGBFFBFFEGGGEFGFGFB000;F0F;FGGEGGEFFF;-.9//B///B9FFFFF/BFFB/:.BB//;FBFFF
+@M01368:8:000000000-A3GHV:1:1113:21679:18011/1
+GATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGAGGGTGTGCACGCGATAGCATTGCGAGACGCTTGAGCCGGAGCACCCTATGTCGCAGTATATGTCTTTGATTCCTGCCTCTTCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAACTGTCTCTTATACACATATCCACGCCCACGAGACTAAGGCGAAGTTCATT
++
+AA>1>11F1D1DDFFFFGGG1FH3GHGHGHGHFHEC?EC0B1FBGFB1GHHH21AF2HH2FEGEHAE10AAE/>/FFHE?/E/?E1@EFFH?E@/EGGG//B11B//<@@C0F/<0<FFDGGCC?FF221<BDD11@<11@DDCGEF1<111F1<F1FBGHGHCF-CHHFA./</0CGHF<0CC/;C-:-;;09;FFBFBBFFBC0FFFGGFC0009C00090/-:--9--;-;AFFE;/99-9--/;///
+@M01368:8:000000000-A3GHV:1:1113:25528:14016/1
+CCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGG
++
+>AAAAFFFBFFFGGGGGGGGGGHHFHGHHHHGHHHHHHHHHHHGGGGHHHHFHHHHFHGHHHHGAFFEFHEGHHHHHHHHGHEHHGGFGGGHHHHHHFHHHHHGGHHHHGGGGGHFHHFF?HHGGFECEFFGHFFGFHGECDGHGBGFHGDF@@?CGFHCEGGGFD.CCC?EGHBHHHFHHFBCFFGEB/CEGGGGDAA.90C9CEBFGGBBF/9.9FBFFFBBFF//99FFFFEABF//99FFEFFFBFF
+@1:A:M01368:8:000000000-A3GHV:1:1113:5741:16959/1_PolyA:1
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+ABBBBFFFFFFFGGGFGGGGGGHHHGHHGGHBGHGAGFFCAFGHGFFGHHGFHHHHHGGGGGHGHHHHHHHHE3BFFHHHGG0EDF@GHFFGGGHGGGGGGGGGGGGGHHGGEEFHGFHHDDG@DGGGHHGDGGGGGHGG?CF?HHGHHHGHGHHHFFHGGGHHHHGGCD.;0<C;CGGGGEFF/.;0;FFFBF/0;0CFGFFB..9B/;0CBFFBBFFFFBAC?DED9;B9AD;.FFFB/B/;FBA/B/
+@1:A:M01368:8:000000000-A3GHV:1:1114:10130:11959/1_PolyA:1
+CGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTCTGATCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGCAACAAACACACATCCAG
++
+>A33>FFFFFF@FFFGGGGFGGD4EGGGGGHHGFFGHFGGHHHFEFHECFHHHEHGAGBCCGCCEGGHGHEGFBFHFHHHHGGGHFHGHEGGGFEGEGG??@DBGHGGC-@FFGHFHFHB-??DA-DD@9:BEBG@B?E?A.ABBFBFA??F.FF/BFFB/B9B/9;BF9FF9FFFFFFFFFFFFFF?BB?;9EE;-;DDB9//;B-B@;ABFFEFFFF/-.9A.;//9/BF./B/..9.9:.../////
+@M01368:8:000000000-A3GHV:1:1114:14540:5315/1
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGGGGGCTATTTAGGTTTTT
++
+AABCCFFFFFFFGGGGGGGGGGHHHHHHHFHHHHGHHGHHGGGHGGHHHHHHHGHHHHHHGGGGGHHFHHHFGHHGGFHHHHHGGGGGHHHGHGGHHHGGGGGGHGHGGGGHHGGGGHHHHHEGDDFGFFFHHGGGGGCDAFCFGFDHHHHGGHGHHHHHHBCGEHHHHGGHG.ACGEHGG0CBFFF:A;BB0;09CGF00CFFFE0AA?//CFFFFFFFFFFFFFFFBEF;A.-=A--:BBFB90;;FE.
+@1:A:M01368:8:000000000-A3GHV:1:1114:15066:16302/1_PolyA:1
+TAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAACGGTTGTTAATTAATTATTGCTTGTAGGAC
++
+BBBBAFFBDFBFBGGGGGFGGGBGFFFHGFHHGFFFHGHHHGHHHHFFHHHGHGC?AEFFHEFBFFFGHHHHH1FDGFFHGHGHFEGCGC-<<AHHHGGGGGGGFHH0GHFCCCADGGG?.9/A-???DGGFFF.9F9/EE-;;BBBFFBFFFFFFFFFEFFFFBFFBBFFFFF/BFFBFFFFF-DBFFF;/BFF//BB//9/BEA---9:BFFFFFF/F/.;.:@9.BBFF/;BFF/;/////9/////
+@M01368:8:000000000-A3GHV:1:1114:16639:15258/1
+CCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGCGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTCCAATATTACAGGCGAACATACTTACTAAATTGTGT
++
+11>>ABFFFFFFGGCGC1BBF1GHHHBHHHHGFHGH1A100AA/GGEHGFBAA1FFD2FHHHHECG2F1BB/E0FC/A>EE/FGGFGEF1EGBBEHHCGGGHBGEHFHE0B?E--;C?CCGGG@A@GBFBBBB09?@??A-AB--ABE@=-=-9AE9A;FFFFFE=9-//;//;9FF/////;;///9B///;/B////9FFBB;--A@-;/9;9-:-/;;FFFE9BF?@;-9-99/B9F/://///99/;
+@M01368:8:000000000-A3GHV:1:1114:2404:13066/1
+TCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCTGTCTATTATACACATC
++
+CCCCCFFFFCFFGGGGGGGGGGHHHHHGHHHHHHHHHFFHHHHHGGGGHHHHHHHHFHHHHHHFGGHHGGHGGHHHHHHGHHFHHHHGGGGGGHHHHHHGHHHHHHHHHHGGGGGGGHH?FGHHHGGGGGGHHGGFGGHHGGGGHHHHHFGGGGFGHGHHGGGGGGGHGGGEGGHHGHHHHHHHHHGFBFFDA0FGGGFFGG0:EFGGGGGGGG;AEBF0B0BFFBFFFFFFFFFFFFFFFFFFFFFEFF0
diff -r 313e04fe07cd -r cc01cbc4e7f7 test-data/trimmed_polyA_reads_pair2.fastqsanger
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/trimmed_polyA_reads_pair2.fastqsanger	Fri Oct 08 09:57:12 2021 +0000
@@ -0,0 +1,396 @@
+@M01368:8:000000000-A3GHV:1:1101:6911:8255/1
+ATCTGGTTCCTACTTCAGGGCCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATT
++
+BCCCCFFFFFFFGGGGGGGGGGGHHHHGHGHHHHHHHHHGGGGGGHHHHGHHHHHHHHHHGHHHHHHGGHGGHHHGHHHHFHHGHHHHHHHHHGHEHEFFGHHEGGCEFGGFHHHBGHHGHHHHGHFHHHGHGHGHGGCDFDDACGGGGGGGAAFFFFFFFFFBAFFFFFB;FFFFFFADDFFFFFFFFFFEFFFFFFFFFFBFFFFFFFFFFFFFFEFFFFFFFFBFEFFFFEFE;DFFFDFBFF/9BFB
+@M01368:8:000000000-A3GHV:1:1101:14518:9998/1
+GTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGAT
++
+AAAAAFFFFFFFGGGGGGGGGGHGGHHHHGHHHHHHHGCGHHHHHHHHHHHHHHHGGGGGHHHHHHHHHGHHGFHFE5BGEEHFGGGHHHHHHHHFBHHGGGGFHGHHFGHHHHGHHHHHHGEGGGGFHFHGEGHHGGCDGDGHGGGDGGHGGCGGGHGHHH/ACDG?.1FGCDCCGCA.CC@CDCHFHGFFGGGEBFGAB//CEFBFGG.:;D;;A0AFFFFFB..:@ABFF//;BFFFFFBF/9D:A//
+@M01368:8:000000000-A3GHV:1:1101:18422:19051/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+CCCCCFDDDDDFGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHFHHHHGGGGHHHHHHHHHGHHHHHHHHHHHHGGHGGHHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHGCGGGHHHHHHHHHHHHHHHHHHHHHHGFDHGFHCFGGGGFGGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF;FFFFFFFFFFFFFFFFFFFFFFFFFFFFEFBFFFFFFFFFF:FFF.
+@M01368:8:000000000-A3GHV:1:1101:25545:21098/1
+ATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATAAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGGCTTATTTAAGGGGAACGGGTGGGG
++
+33AA?DFD5BDFGGGFEBDGEGHEGHGEGHCEGGHHCHGHHFFHHGFGAGE53FF2FAFFGDE5FFFE5GFBFGAEE1GHHHGHHHEHE3FGHF@GEGEGGHHGG3FAGFFDE?EEE3GFEGFGFGGCG?GHHHFHGGGC@DHFFHD/A<C@EGFDCGGGHFHHHEGFGHBFHG0:CEHFCHGGED.;0CEF.F99B0CFFEEFGGG0FBFBBF0F/FFBDE?/9//9B.FFBFFFFFFBF..A..;@B--
+@M01368:8:000000000-A3GHV:1:1101:5446:12248/1
+AATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTAT
++
+CCCCDFFFFCCFGGGGGGGGFGHHHHHGGGGHHHHHHHHHHHHHHHHGBGHGGHGGHHHHHHHHHHGHGHGGGGGHHHHHHHHGHHHHHHHHHGGGGGHHHHFFGHHHGGGGGGHHHGFGGHHGGGGHHHHHHGGGGGGHGHHGGGGGGGHGGGGGGHHHHHHHHHHHHHFHGGGHHHHGGGGGG:FE;EGEGGGGG/;?FGGGGGGGFFFFGGFFFFFFFFFBFFFFFFFFFFBFFFFFFEFFFFFEFFF
+@M01368:8:000000000-A3GHV:1:1101:5861:6452/1
+ATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTT
++
+ABCCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHGHHHHGHHHHHHHHHHHGGGGHHHHHHHHFHHHHHHGGHGHGGHGGHHHHHHHGGHFHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHHEGGHHGGGGGGHHHGGGGHGGGGGHHHHHHGGGDCGHHHHGGGGGGGHEFGGGGHGHHHGHGGGFGGGGGGGEGGGGGGG?E0CEFGGGGGFEE9EEFFFFFBFFFFFFFBFFBD.AFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1102:10403:6021/1
+CGCTCCGGGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTG
++
+>A@AAAAD2ADDFFGGGGGFGGHA?EAEFBEAGHFABFGG5FDF5DB1EEGAFDFB53FF5FH@G5FFEHGHEFHFFHBE333GF43GCGGGGE@0?BFGGB0B?FHGFDGGHHHBFFDEGGHGFFFDFE@<1>@FFFGHHHHFHEFGDABFFGG/@DCE<CG1<GF0/DD000=<DHGBDFDCECE/:AC?-;-;9B/ABBB-AD9BFB99AB?BDFBAD-.9..@;=;;..9..9/9;BEF;A:9/BFF
+@1:A:M01368:8:000000000-A3GHV:1:1102:10677:23253/1_PolyA:1
+CCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTCTGTCTCTTATACAC
++
+ABBBBFFFFFFFGGGGGGGCGGGHHHHHGHHHHHHHHHGHHHHHHHHHHHGHHHHHGGGGGHGHHHHHHHHHHHHHBGFHHHHGHGHGGHGGGCGGGHHHGGGGGGGHHHGHGGGGGGGGGGGGGGGGGGGGFFFFFFFFFFFFFFDFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBFFFFFFFFFEDBDFFFFFFFEFFFE0F0FBFFFF0FFFFFFFFFFFFFFFFF
+@M01368:8:000000000-A3GHV:1:1102:13809:1733/1
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGAGGGCTATTTAGGTTTTATGCTGTCTCTTATACACATCTCCG
++
+BCCBCFFFFFBFGGGGGGGGGGHHHHHHHHHHHGHHGGGGGH3EHHHGHGHHHHHHHHHGGCEGGGHHHGGGFHGGGGGGHHGEAEFHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGCFFGHHFGHHHGHHHHHHCHGFHHHHGGHGGG00EHGHHHGFHHGEHGHFFFHHGGFHHHGGGGGGGGGB;;CFFGGFGFFBFFDFED;E.:A?DFFFFFFFF:FFFFF0BFFBBBFFFFFBFF0BFBF9F.
+@M01368:8:000000000-A3GHV:1:1102:17584:10050/1
+ATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCT
++
+CCCCCFFFFFFFGGGGGGGGGGGHHHHHGGHHHGGGGGGHHHGFGDHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGEGGHHHHHHHGHGHHGHHHHGHHHHGGGGFDGHFHGEHHHHHHGFFHHHHHHHHHHHHHHHHHGGHHHHHHHHHHFHHHHHHGGGGGHHHHGGGHHGHHHGGGGGGGGGGGFGFFGGGGGGGCFGGGFGGGGGGGFFFFFFFFFFFFFFFFFFF;.BF9ADF/9;A;DFFF0
+@M01368:8:000000000-A3GHV:1:1102:18842:24844/1
+CACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCT
++
+BBBCBFF@CCBBGGGGGGGGGGHHGHGGHHHGGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHHFHHHHGGGGGHHHHHHHHHHHHHHHHHHHHGGGHGGHHHHHHGHBFGHHHHHHHHBGHHHHHHGHGGGHFGCGGFHHFHFFHHBHHHHFFHFHHHHGGDHGGBC?;@DFBFFFFFFFFFBFFFFFFFFFFFFFF.B?FB.@;;DFFFFFFFFFFFEE-A./BBBFBFBFFF//BFB/BFF/
+@M01368:8:000000000-A3GHV:1:1102:21788:11027/1
+GCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTCTG
++
+ABCCBCCBBFFFGGGGGGGGGGGHGHHHHHHGGHGGHHHHHHHHGHHHHHHHHHHHHHHHHHHGHHHHHFGGGGHHHHHHHHHHHHHHHHHHHHHHGHGHGGFCGGCGGGHHHGGGGGGGGGGGGGGGGGGGGGGGGGFFFFFFFFFFFFFFFFFFFFFDFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEF9EFFFFFFFFFFFBFF0FFBBBBFBFBFFFF0
+@M01368:8:000000000-A3GHV:1:1102:5728:8777/1
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATG
++
+BBBBBFFFFFAFGG5GGGGGGGHHHGHHHHHHHHHHGGGGGHHHHHHGHHHHHHFGHHHGGGGGFHGHGGGHHHGGGCEGHHGG?F1BGGGGGHHHHHGGGGEGGHHHHGGGGGCGHGGGGCGHHHHHHHHHHHHHHHHGGHHHHGGCEEDFDEGGHHHHHHHCEHHFHHHHGHGFHHHFFGGGFFFGGFGBGFFFFFFFFGFDGGD9EFA.DAFA/;FEFF9FB?/BBF/FFFFBBFFFFF/FFEFFFBB
+@M01368:8:000000000-A3GHV:1:1102:5983:21093/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+AAABCFCABBCFGGGGGGGGGGHHHHHHGFHHHHHHHHGGHHHGHGHHHGGGGFHHHHHHHHGHHHHHHHHHHHHHGGHGGHHHHHHFHGGHHHHFHGHHEHHHHHHHGHHHHHD@FGGHHHHHFFFHHGGHGH?DHHHHHGHGHEGG/@?ADGFGGFFFFAFFFFFFFFFFFFFFFFFFFFFFFAAFFFFFFDFFFFFFFF;D9BFFFFFFFFFFFFFFFFFEFFFBBFFF0BFFFBBFF0EFFFFFFFA
+@M01368:8:000000000-A3GHV:1:1102:7765:18353/1
+CTCCGGGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTC
++
+CCDCCCCCCBCFGGGGGGGGGGGGGGGHHHHHHDHHHHHHHHHHHGGGGGHHGHGHHHGHHHHHHFHHHHGHHHHHHGHGHHHGHHHHHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHHHHHHGFFHHHHHGHHHHHHHHHHHGHHHHHGCFGGHGHFHHGHGHGHHHHGGFHHHHGGGHGBFGCC=BFFFFFFFF-@DFFFFFFFFFFFFFFFFFFFFFFAFFAEF.::FBFBFFE-A9:BFFFF0
+@M01368:8:000000000-A3GHV:1:1103:10405:17879/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+CBCCCFCCCCCFGGGGGGGGGGHHHHHHHHHHHHGHHHGHHHHHHHHHHHGGGGGGHHHHHHHHHHHHHHHHHHHHGGHGGHHHGHHGHHGHHHHHHHHHCGGFHHHHGHHHHHGCFGGHHGHHHHHHGFHHHGHHHHHHHGHGHGFF/CC?ADAFGFFFFFFFFFFFFFFDFFFFFFFFAFFFFFFFFFFFEDFFFFFFFFFFAFFFFFFFFFFFFFFFFFFFFFFBBFBFBFFFFFFFFFFFFFFFFF?
+@M01368:8:000000000-A3GHV:1:1103:13493:8205/1
+GTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATT
++
+CCCCCFFFFFFFGGGGGGGGGGGGGGGHFHHHHHHHHHHHHHHHHGHHHHHHHHGHHHIHHHHHHHGGGGFHHHHHHHHHHHHHHHHHHHGHGGHGGHHHHHHHHHGHHHHHHHHHHHHHHHHHGHHHH/FGGGGHHHHHHHGGEHHHHHGHHHHHHGHGHEFEFGGFFFFFFFFFFFFFFFFFFFFFAFDFFFFFAFFFF;;@FFEFFFFFFFFFFE=?AFFFFFFFFFFFFFFFFFFBFBBBFFFFEFF
+@M01368:8:000000000-A3GHV:1:1103:14060:21273/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTACTGTCTCTTATACAC
++
+AAABAFCCCCCFGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHGHHHHGGGGGFHHHHHHHHHHHHHHHGHHHHGGHGGHHHHHHHHHHHHHHHHHH?GGHHHHHHGHHHHHFEGGGHHHHHHHHHHHHHHHGFHHHFHGHGHGFGCGG@@BCFGFFFFFFF?FFFFFFFFAFFFAD?@FFEEFFFFFFFFFFFFFFFFFFD9BFF/B/FFF/:/9FB9/BFA//;BFB:FFFBB/BFFFFFBFFFFB/
+@M01368:8:000000000-A3GHV:1:1103:14528:12993/1
+GCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGAT
++
+BBBBBFFFBDFFGFBCG2EGFFGHHCF5AFHHHFHFHHHGG?CEHBHHDGFHHGHHGHBGHABFFBGHGDGGGFHGHHGGHHHGGG@E1GEHHHGHHFHH3FEDHHHHGFGHGFHHGHFBGA?FGHHHHHGHHFFGHFDFGGHHH2??<ECFHHGHHHHHHHHHGHH<1DFGHGC<.FCB/<=@DCFFFFFEDA=-AAB9B/9B9B-@?.-;A-AFF.=-=BFEFEDEFFFBFEA-A.B//9F9F//;BBB
+@M01368:8:000000000-A3GHV:1:1103:17657:20856/1
+AAAGCGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTAT
++
+ABB?AABBBBFFGGGGGGGGGGHHHHHHHHGHHHHHHHHHHHHHHHHHGHHHHHHGHHHHGGGGGHHHHHHHGHHFHHHHHHHHHHGGGGGHHHHHHHH3BGGHHHHHHHEHHHHHHHGHHHHGEEGGGHHHHHHHHGHHFHGHGHGHGHHCHGGECCDFGB@AFFFFFFFFFFFFFFFFFDAFFFFFFFFFFFFFCAF;AFFFFEFFBBEFFF9FBBFFFFFFFFFFEFFFFFFFFFFFFF/FFFFBFF9
+@M01368:8:000000000-A3GHV:1:1103:23099:3794/1
+AAGACAGATACTGCGACATAGGGTGTTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCTCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGGATGCCGTCT
++
+BBBBBFFFFFFFGGEEGGFGGGGCFGEHCGGGGGGFHFFEDEHFGGDEHHHHHHGGFECGHHHHGFEFGCGHGGFGGGHBGFH3/BF3GGGHHEEEHHG22???BCFFFFFFHHFHFF@FGHH11GHHHHFGFHHHHGGHHHHEFFGFGHFG1DGFGGGGEDCCCAEGGFFHHFHHHHHHCFBBFGBFFF/0;B0B00;B0BBFGBB9BFGEFGGGFFDEEAB;BDDBFBFFFFF@;.9BF..;-./-A=F
+@M01368:8:000000000-A3GHV:1:1103:25465:20010/1
+GACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATCGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGAAAAAAAAAAAACAACAGAC
++
+ABBBBFFFFBAAGGGFEFGGGGHHFEFFHFGGGGGHHHGHFGGGGGHHHGGGGGGGGHGEEEGGHHHGFHEHFHDGHGHEHGF?FGG?GGGGHHGHF4F?2?DDCDHGHHHHHFG2@FGHHHGH?CFGGHFHFHHHHGDDGGHGGGGGHGFH.<AFAGHHHFHGHHFCGFHHHHHGHHHHBGHHGGDGAGF.CEGCFDGGGGGEFFF=B.FFFEFFFFFFADF?/9//BFF.B/;:>---;--..;.../9
+@M01368:8:000000000-A3GHV:1:1103:25519:6301/1
+AAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGCATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATTTCGT
++
+3A3AAFFFFBFFGGG2CF?4FGHGHHCHGGHHBHGFFAGGHHFFHHCGHFEGCECEGHFFFHGHHGFGHFGDAFDGFFEEFEGGBECC/<A@DFBBEGC--:;GHHHGBECG@:9-9.-9C/ABB?B@?.EDAFFFFBAFBFBFBFFFFF//;BBFFFF/;/9BBF/BBFBFFFFFFFFFEFF??BF/.AF./;B/9FFFFFFBFBFFFBFFFBFFFFF/BF/A---9.9A-B?DFFF/B/B?---.//;.
+@M01368:8:000000000-A3GHV:1:1103:6074:6549/1
+TAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTG
++
+CCCBCFFFFFCCGGGGGGGGGG5GFHHHHHGHHHGGGGGHHHGHHHHHHHHHHHHGHHHHHHHHHGGHHHHGHHHHHHGGGGHHHHHHHHHHHHHHGHHHHHHHGGHGGHHHHHHHFGHHGHGHHHHHHHHHHHHHGHHHHHGGGGCHHHHEHGHHHEGHHHFGGHHHHGHGHGHF@CCBDFAFFFFFF-CDFFFFFFFFFFFFFAFFFFFEFF;BFF?FEDFFFFFFFF-A./FFFFFFFFFFFF/BFF/
+@M01368:8:000000000-A3GHV:1:1104:11572:8264/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+BABCBFBACCCFGGGGGGGGGGGHHGHHGHHHHGFGCHGHHGFFHEHHHHGGGGFGHHHHHHHHHHHHGHHHHHHHGGGGGHHHFFHHGHHHHHHHHHHHEHHHHHHHGHHGHGGEGEGHHHFHHHHGHHHHHHGGHHHHHGHGEGEHCGG-BGDFGFFFFAFFDFFFFEFFCFFDDFFFFFFFEC>;>=EF?AEFFFF;9;=DAFFFFBBFFFBFFF//;BFB.:FBFFBB/BFFFF/BFFE?EFAFEF9
+@1:A:M01368:8:000000000-A3GHV:1:1104:11928:24197/1_PolyA:1
+ACGTAGGTGCGATAAATAATGGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGAT
++
+CDDCCFCFFFBCGGGGGGGGGGHHHGHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHGGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHHHHHGHHHHGHHGHHHHGGHGEEGGGGFHHFHHHGHGEHHHHHHHHHHHHHHHHHGGGGGGFGGGGGGGGFFGGGFGFGAEFEFGFEAFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF@D
+@M01368:8:000000000-A3GHV:1:1104:12288:20635/1
+CACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGCCGCAGCATCTGTCTTTGATTCCTGCCT
++
+ABA?AFBAB2>AFGGGGFFGD5GGHGFFHGHEGGGGHHHHFFHH5FHGHHHFFHEFHHHHHHGGHHHHHGFHGGHGGGGFHGGGFBHHHFGEGHHHHGHGGGGECEHHFHHGHHFFHFGGGHHHEGHDGHHGHGHFHHHECGCBCHHGFHHFHD1GFHEFHEF?GDCFFEFE0A@;@>BD/9BFBBBBFDFFFF99D=?>DDBFF-AFFEBB9BBEFEFAFFF//-@---;;FBBFBFB///;99999BA9
+@M01368:8:000000000-A3GHV:1:1104:13832:4398/1
+CACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGACAAAAAAAAACACACAACAACCAACACCCAGTAGACTAGTGCGTC
++
+AAABABCAFFFFGGGGGGGGGGHFHHHHHHHHHGFFHHGGHGGGGGHHHHHHHHHHFHHHHGHHHHHGGHGHGGHGGGGGGGHGFFGGGGDGGHHHHGGGGFGGGGGCFGGEGCDGGGGGGGGGGGGEGF?;BFFFFFFFFFFFFFFFFFF:FFFFFFFFFFFFFFFFFFFFFFF/FFFFFFC.;BFEAFFFFF;@FFBFFFFEF?/FFFFE----:...:...9....9.9...:.9//9////;/9-.-
+@M01368:8:000000000-A3GHV:1:1104:23670:4161/1
+ATTCAATTGTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCC
++
+AAAABFFFFFFFGGGGGGGCGBBGGHHHHHHHHHGHHHHHHHHHHFGGHHHHHHGGFHHHHHHHGGGGGFHHHGHHHHHGHHHHGHHGGGHGGGGHHHHHGHHHHHHEGGGFHHHGFFDGEGHGHFHGHHGEGGGHHBGHGGHGHGGGGG/@FCDFDGFHGGGDFFHFGFFGGGGGHHHHGGGGGGGEGCDG?GGBFFFEE00BFFGABBBAFGGGEGEA.9FFF/./;BFBF./AAF/BFFBBF/F/BFB
+@M01368:8:000000000-A3GHV:1:1104:24927:22253/1
+AGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTAT
++
+AAA?AFFF3DFFFGGBGFF3EAEEEHFHHFHHHGHHHHDGHHGAEFGHHHGFCHHGHHHBGHHHAEGGHGGFHFBFHHHHHHHHHHFHH1EEHEEHH1FFDEEFCGHBGHHFHEHHHHHH1FCGHHHHEEFGEEGFFCHHH11>GHHF/FG2DGGCGAGGHGGGG@@@BEFFF?@@@FFEFFFFFF?@@FB@BB@FFFE=;==---A9EFBBB/;E;A9B/B/FFFEF/B///;/;9/A/;/9BFFFBFBB
+@M01368:8:000000000-A3GHV:1:1104:4705:7727/1
+CTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGG
++
+BBBBBFFBFFFFGGGGGGGGGGHHHGHHHGHHHHH6GHHHHFFGGGHHHHHHHHHHHHHHHGGFGGGEGGGHHHHHHHHHHGHE3FGGGGHHHHHFHHHHHHHHHHHHGGGGGHHFHFCGFHHGGGGGGGHHGGGGHHGGGGGGHHHHGGGADCHHHHGDGGGGGGGGC@DGFHEHHHHHHGHHHHGFGDEGFGFFGGGGCFGBEGFGGGFG;C.BFFFFFFFBFBFFFF/F?.AFFF/BFFEFFFFFEFF
+@1:A:M01368:8:000000000-A3GHV:1:1104:7756:4776/1_PolyA:1
+GGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTG
++
+CCCCCCFFFFFFGGGGGGGEEFHHHHGHGHHHHHHGGHHHGGGGGGHHGHHHHHGHHGHHHGGFHHHHHHHHGHHHFHHGHHGFGGGGHHHHHHHHGHGHFFHFHHHHHHGGHGFGFHHHGHG?FGHHHHHHHHHHHHHHGHGHHGHGGCDGFFHHHHGHHHHHGHHHGFHGHFHGHGHGH/@CABFFFFFFFACAFF?BBFFBFD-@-.D>FFAF.F.:9---;AADFFFFFBEFFF:9FFFFBBFFFF
+@M01368:8:000000000-A3GHV:1:1105:11310:21761/1
+ATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTTCACTTT
++
+CCCCBFFFFFFFGGGGGGGGGGGHHHHHHHHHHHHGHHHHHGGGGGHHHHHGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHGHHHGHHHGHGHHGHHHHGGHGGG=FFGEHHHHHGHFGGHHGHHHHHFHHHHHHHGGHHHHHHHGHEHHGHHHHHGGGGF9AGE?DEGFFGGGGGGGGGGGGGGFFFF/9FFBFFFFFFFEFFFBFFFFFFFFFFFFEFFF0
+@M01368:8:000000000-A3GHV:1:1105:11578:14676/1
+ATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTC
++
+CDDDDFFFBFFCGGGGGGGGGGHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHFGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHHHHHHHHHHHHHGHHHHGGGGGGHGGHGHHHHHHH;CHHHHHHHHHHHHHHHGHGGGGFGGGFGGGGGGGGGGGGFGGGEGGFFFFFFFFFFFFFFFFFFFFFFFFF/FFFFFFFFFFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1105:13575:19255/1
+TTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGTTCCCGTGAGTGGTTAATAGGGTGATAGGCCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+AA1A1DFFFFFBGG3A111FFAEGDDBGFDHF00F01BBA00BFGEHFBFFA1FABB0FAE?CFHF1BGFHFB0011F121E//>>1F10>B?EFHGCC/?/BFG/EEGFFEE//BCFDE0?E@@B/?11</?//<@?/F<<<A-<FBGH0.00=G0<<C//./0;;GC....<C.=.00;;BB./:.900////.C000;0090;..//000;C/;;/B/9BA9A9-AEEFF?B---;B99//9/;A//9
+@M01368:8:000000000-A3GHV:1:1105:15502:11453/1
+GTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCTGTCTCTTATACACATCTC
++
+A3AAAFFFFFCFGGGGGGGGGGHHGHHHGHHHHHHHHHFGHHHHHGGGGHGHHHHHGFHHHHGHGGGHHGGHGGHHHHHHHHHHHHHHGGGGGFHGHHHGHHHHHGHHHHGGGGGGHGEGFECHEHGGGGGGHHHGADFHHGGGGHHHHH<ECGGGGHHHHGGGGGGGHGGGGGGHHHGHGHHGEHBFFFGFGEGGGGGEDEGF0C;;BFFFGGGBEFFE/FFFFFFFFFFFFFFEFFFFFFFFBFFFBFF
+@M01368:8:000000000-A3GHV:1:1105:16787:9771/1
+GTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGAT
++
+AABCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHHHHHHHGHHHHHHHHHHHHHGHHGGGGHIIHHHHHDHHHHHHHGHHHGGHGGHHHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHGGGHHHGGGGGGHHHGGGGHHGGGGGHHHHHGGGGGGHHGHGGGGGGGEEGEGFGHHHGGGGFFGGGGGGGGGGGGGGGEG?G;:EFFFFFFFFF:AEFFFFFFFFBFFFFFFFFFEFF/
+@2:A:M01368:8:000000000-A3GHV:1:1105:17564:15723/1_PolyA:2
+TATGCTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTG
++
+EDCCDFFCEEDCGGGGGGGGGGHHHHHGFGHGGHGGHHHHHHHHGHHEHHGGGGGHHHHHHHHHGHHHGHHHHGGGGGHHHHFFGHHHGGGGGGHHHGGGGGHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHFEHHHHHHHHHHGHHGHGGHGGGCGGGGHHH1FGGGFGGFGGGGGGGGGGEFGGGGGGGGGGGGGGGGGFFFFFFFFFFAEFFFFFFFFFFBBFBBFFFFFE1:BFF
+@M01368:8:000000000-A3GHV:1:1105:18108:12091/1
+TAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACAC
++
+CCCCCFBFFFFFGGGGGGGGGGHHHHHHHHHHHHHGGGGGGFHHHBFGHHHGGGGGGHHGGGGGHHGFGGHHHHHHGGGGGGHGHFGGGGGGDGEGEFGCHHHHHHHHHHGHHHHGEDHHHGGGCDGGGGFHFHGHHHGHHGHFGHHHFHHGFHHHFHHGGHFHFHHGB0CGHGFHCBGGGGEDEE9ADFEFFFGFBFGFFGGFFFFFGGFGFFFFFFFF/A?FEFFFFFEF-A.B//;BFFEF//BB///
+@1:A:M01368:8:000000000-A3GHV:1:1105:18331:16683/1_PolyA:1
+TCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATT
++
+BABA?DFFFFFFGGGGGGGGGGHHHHHHGHGHHGGGHHGHGGGGFFHHGHHHGHHHHHHH3FGHHGGGHGGHHHHFHHHFHGHHHGHHHHHHHHHHHHGHHHHGGCGGGHHGHHHHHHHHHHHHHFHHGHHGHGHEFGGGGABFFFGBEGGAFFFFFFFFFFFFFDDFF?DFFFFFFFFAEFFFFFFFFFFFFB;9FFFFFEFFFFFFFFFFFF?FFFFFFF/BFFFFFFFB.DABFFFFFFB.//:FB/
+@M01368:8:000000000-A3GHV:1:1105:20577:18421/1
+GGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCC
++
+ABB@3>AAFFFFFEAGGGFGGAA6FHDGGCGFHFFHFHFHHHHHGDDDFFFHGFFHGBEGEGHHHFFFHGEEAEGHHHHHFHHHFHGHFEDGGEGBEAGEFHHFFHHHHHHGGHHHGHHGBGHHFHHFGHHHHG?CG?AFHH1FHHHGHFHHHF?DGHFFHCGAGEFHGCBBBB?BFFF?B-B.9/BFFFFFB=-AD?..@FFFF@@-@@?AFD.FFFBBEEBD9/:FFFFFBB/:FF9BF/BF.BBFF/:
+@M01368:8:000000000-A3GHV:1:1105:21099:2895/1
+TAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTT
++
+CBCBBFFFFFFFGGGGGGGGGGGGGFHHHHFHGHHHHHHFHHHHFGFHHHHHHGHHHHHHGHHEHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHHHHHHHFHHHHGHGHHHGGHHHHHGGHFFGHGCGGGHGHHGHHHFGHHFHH/FGGGHFGFEGGCFCCD;B@DFFFFFFFFFFFFFFFFFFFFFFFFF;F.BEFADFFFF.AEFFFFFFE;D.;:B00099:09BFBFFBFF.0:000BFFBF0
+@M01368:8:000000000-A3GHV:1:1105:26469:19245/1
+TTATGATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCAAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATG
++
+BAAAAFFFBFFFGGGGGGFFGGHHHHHHHHHHHHGGHHGHHHGGHHHHHHHHHHHDEGGHGHHHHHGEDHFHGFHGGHHGGHGGEHHHGHHGHHGHHHGGEGGGHGHGHHHHHHGHHHHGHGGGGGHFHGGGGHHGGGGCDGHHHGD<EHHGGGGGHHGHH?EDCCDHHHHDGFFGGGHGGFCGGHHHHFG.CFGGGGGGGGGGGBFGDEG.AFFG;AFFFFEB?/A9BBBFFFFFFF/9FFFFBDEFFFF
+@M01368:8:000000000-A3GHV:1:1105:7169:17145/1
+AACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGT
++
+CCCCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHBHHHHHHHGGHGGHHHHHHFHHHHHHHHHHHHHHHHHHHHGHHHHHGGGGCHHHHHHHHGHHHHHHHFHHHHHGHGHGHHGGGGGFGGHHGGGGGGGGGGGGEGGFGGGFFFFFFFFFFFFFFFFFFFFFFFFFFFDFFFFFFFFFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFFFFFFFF-9@DDBFFFFFFFFBBFFF0
+@M01368:8:000000000-A3GHV:1:1106:15481:16176/1
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTT
++
+ABBBBFFFFFFFGGGGGGGGGGHHGHGHHHGHHHFGHGFGHFEHGGHGGHHHGHHHHFGHGGFGFFHHFHHHHEGHFHHHHHFGGGGGHGGGHGFHGHGGGGGGHHHGGGGHHGGGGHHHGGHGGGGGGHHHHGGGGGCFHGGGCDGHGHHHFHEHHHHHHHHHEEFHHGG:C:?0<EFGBFGGGGGFE.BFGEFFFGFFGGGGGGFDEF/FFGFFFFFFF;BBFA;.:EFFE:AAFEF.BFFFFF;9FF.
+@M01368:8:000000000-A3GHV:1:1106:17389:18671/1
+CCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGGCTTTGATTC
++
+3>>A@FFFFFFFGGGFEECFGGFFB5GBHH5DFH5GBEEAEFHFHHF3F3GHFHHHEF3GAEHBGFHFFEFFHHHHFFB31FGGEGFHGEHHHHHHHHHHHHHHHHHEEEEGHHHFFF3GF3FGF44BBGEHHHHGG2B/BGGHE</ECDFHHBF1DGBFBFGFH<1GHGDGGFDFE0/<--;-9./BBED;BFBD/BF9BFFFDBFDADD;FFF?->;B=.9.;.BBFFF..;A;/B/;B//;;//BBF/
+@2:A:M01368:8:000000000-A3GHV:1:1106:22927:3863/1_PolyA:2
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGACTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACT
++
+A>ABAFA?D@AFGGGGFGGGFGFHHHFFH4BCBGHHHHGFFF3G5BF3322EEAFHHHHHHAB5GHFHEHFHHH3BEEHFGF5@13FDF3GDGFHHFGHHHGHHHGFGGHHFCG//?/EGHHHG3F4BFFGHHHEDGFHHB/B/?FBF<@-9?BDEFFF?B--?DFFFB9FA>B;A.BFDB?AB.--@;-.FFAEFFFF9AE;DDFFFFB/9BFFFFFFFB:BF/BB/BFF//FFF-=--.99=--.9/
+@1:A:M01368:8:000000000-A3GHV:1:1106:23625:4236/1_PolyA:1
+TAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATT
++
+@?AAAFFBFBFFFGGFGFGGGEFCGGHHHHFGHGHFHGHHHHGGFGGFGHHGHGHHHHGHGFFHHGGGGGHHHHHHHHHBFHHEFHHHHHHGF?FAGHGFHHHGDGFHHGGGHGHFHHHGHHHGHHFHHGFFGFHHHGHHHHFFHHHHH/FGHHHHGHGHG<C???B=@ABBFEF@=-AFFFFFFBFAFFDFFFFA?AFFCFFABEFFFFFFFFF?FFFDFFBFF;FFEFFEFFFFFFFAF///9FF/BB
+@1:A:M01368:8:000000000-A3GHV:1:1106:26031:14826/1_PolyA:1
+GATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATATCGTATGCCGTCTTCTGCTTG
++
+ABBAAFFF@FFFGGGGGGGGGGHHHHHHGHHHHHGGGGGHHHHHHHHGHGHHHHHHHHHHHGHGHFHFGE?CGDGGHHGGGGGGGHHHHGHGGGGGGFGGGHGHGGGGGGGGGGGGGGGGGGDGAFFGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFB/9FFBFFFFFFFFFFFFFD@D=BEFFF;FDDB////B=CF-.;BAFFFFFF;;BFE/BFFFFB
+@1:A:M01368:8:000000000-A3GHV:1:1106:27607:15990/1_PolyA:1
+GACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGACTTCTGCTTGAAAAAAAAAAACTACAACCCACGGACGC
++
+BBBBBFFFFFFFGGGGGGGGGGGGHHHGGGGGGHHHGGGGGFCEGGHHHGHHGGGEGGHHHAFGGGGGGAFG//EGHHHHCGEHHHHEEHHFHGHFHHGGEF/FGGC?FDFH2DHHFFGGFGHHHHGGHHFGHHGHGHHGFHDHBGBBGHHFHHGGCCDC<=D<DGHHC;CGFCCFBECDG?FGGA-;EB9FBGFFBBF>DFFFE?FFF/--;;9/:BFFFBA///9----;B.//////;...---9--
+@M01368:8:000000000-A3GHV:1:1106:6455:17124/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+BBBAAFABDBBFGGGGGGGGGGHHHGHHGHHHHHHHHHGHHGHHGHHHGHGGGEGHHHHHHHHHHHHHGHHHGHHHGGHGGHHHHHHHHHHHHHHHHHHGHHHHHHHHGHHHHHGGCFEHHHGFHHHHGHHFFH?GGHHHHGHGHGHHCFGGGGGGGFFFFFFFFFFFFFFFFFFFFADFA?.FEFAFFFEFFFFFFFFFFFFDABFBBFFFFFFFFEFFBFFFFFFFFFFF/FFBFFFFFFADE>BFFF9
+@1:A:M01368:8:000000000-A3GHV:1:1107:14451:26748/1_PolyA:1
+GTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTG
++
+BABBBFFDABBBGGGGGGGGGGHGHHHHGAGHGGGGGHHHHHHHHGHHHHHGGGGGGFFHHHHHHHHHFHHHHHGGGGCHFHH3FEHHGCGGGDGHHHGFGGHHGGGGHHHHHHG/DGGGHHHHGGGGGCCHGG?CGG1GHHGHHHHBGHHHFHHGHHHHGGADAD00ECEGHEFHHFFAEFFFFFGGFBFBFFFGFFG.;B/99;BCFGGGGEFFFFFFEDA./:ADEB?FBFFFF;FFEBFBFFB./9
+@1:A:M01368:8:000000000-A3GHV:1:1107:18714:24788/1_PolyA:1
+GTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTG
++
+BBBCCFFFDEDEGGGGGGGGGGHHHHHHGGHHGGHGGHHHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHCFGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHGHHHHHHHHHHHGHHHHGGEGEGCCEGGHHHHHHG:CAFFGGGGGGBFEFGGGGHGAFFGGFGGGGGGGEFFFFFFFFFEF/EDDFFFFFFFFFBFFFFFBBFFBBF
+@M01368:8:000000000-A3GHV:1:1107:21355:8333/1
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATG
++
+ABCBBFFFFFAFGGGGGGGGGGHHHHHHHHFHHHHHGGGGGHHHHHHFHHHGHHHHHHHGGGGGHHHHFFGHGHGGGGGGGHGGEGGGHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHGHHHFHHHHHHHHGHFFHHHHGGHGEGHHGHGFHHFHGHCEFHEGHGHHHGHHHGGGGGGCFFFFBFGGFGGGGFBG?FDGGGEGFFFFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBFF.AA/9
+@M01368:8:000000000-A3GHV:1:1107:22864:15712/1
+AATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATG
++
+BBBBBFBBFFFFGGGGCEGGGGHGHHDGFHHHHHHHHHHHHHCHHGHFGBGDFGE?GHHGHFBHHFHHHHHHHHHGHFGFGHGHHGGC@DCFGHHGGGGGGGHHHHHHGGGGGFGGGGFFGGGGFADGFEFFFFFFFFFFF9;FFFF/BFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFEAECDFFFFFFFFFBFFFFFFFFFFFFFFEFBFBFFF/FFFDF-;-9;E@>-9DFFF/FFBF;-.:;.9A//
+@M01368:8:000000000-A3GHV:1:1107:24817:14233/1
+CTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACAT
++
+3AABABFFBFFFGCFGGGGGGGHHHFGCFGGGFFGHHCGHHHGHGHGHBFFHHHEDGGFGFGHHFFFHGGEGHFHHGHFHGFFHHHFGHHHFHACECEHHHBGFHGFHHHFHHF4GFHFHFHEHGGE/EG:A-CFGGFGADGGGGFGGGGDAAAADFA.-AFFECFDAAFFFFEFFFFBFF;D;BFFFB/;BFFFFFFFFFFFFFFBFFBF/;//;BFFFF?FFFFFFEDAFFFFFBF//:BFBACF--9/
+@M01368:8:000000000-A3GHV:1:1107:24830:14440/1
+AACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACC
++
+ABBBA@FFFFBBGGGGGGGGGGHGHHGHHGHHHGGHHHHHGHGHHGDHHHHHHAGGGGFHHGHHHHHHGHHHHHHHHHHHEGAFGFHFHHHHGEGHHHHHHHHHHHHHHHHHGGHHHGEFEGGHHGHHHHHGGHGFHH/?GHHHHGFGHGFHCGGBBDAFFFEFFFFFFFFFFFFFF=CDDADDFFFFEF=BFFFEFFFBFFFFEEBF./:FFFFFFFFFFFFFFFFFFFEFFFFFFFFFFF/BFBEFFC-
+@M01368:8:000000000-A3GHV:1:1107:26478:23602/1
+GCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATCTGTCTCTTATACACCTCTC
++
+1AAAAF1B13BBBEGGGFGGGGGGHHDB1BGFHHHFGFGGG0F00BGBGFGGF1GBGB1BGCGAEE/FGFHGHFHHHHHBFF1B0FGGF//F//FGFGFFF/1@B1DFHHHGGEFEDHFDFAFF0B//</ECCC>1FDD1GFFHHDF?1BD>GF/GCAC0C@?@-;99BBB->@--;-B//99B--9-BF=A--A-:A----9AA9AFBFBBB?E@BBFFFFFFFBFFFFFBFFFBBFFF//B/////-;9
+@M01368:8:000000000-A3GHV:1:1108:11059:23181/1
+GTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGAT
++
+CCCCCFFFFFFFGGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHHHHHHHHGHHGGGGHIIIHHHHHHHGHHHHGHHHGGHGGHHHHHHHHHHHHHHGGGGGHHGHHHHHHHHHHHHHHHGGGGGHHHHHFGHHHGGGGGGHHHGGGGGHGGGGHHHHHHGGGGGGHGGHEFGGGGGHGGG-ECHHHGGGGGGGGGFGFFGGGGFGGGCF?EFGG0;BFFFFB?9AAFFFFFFBF;BBFFBFFFFE?F/
+@M01368:8:000000000-A3GHV:1:1108:12233:13498/1
+TAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCCTGTCTCTTATACAC
++
+BCCBAFFBCCCCGGGGGGGGGGHHHHGGGGGHHHHHHGHGHBGFHHHHHGGGGGHHGGBFGHHGGGGGGGHHHGGGGHHGGGFHHHHHHGGGGGGHGHHGGGGGGGGGGGGGGHHHHFHHHGHGHHHHHHGHGHHGGFGGGDFFGGHHHGHGH/<GHHFGBGFHFBGHHHGHHGEFHFHFGBF0BFGGGFGGGGGEFFF;A?EEG?CFFFFF0:BEFFFFFBFFFFFF0FFEFF?EFFFF0BFFFFBBB00
+@1:A:M01368:8:000000000-A3GHV:1:1108:14328:14751/1_PolyA:1
+ATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATAC
++
+BCCCBFFFFFFFGGGGGGGGGGHHHHHHHGHGHHHHHGGGGGFHHHFFDGHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHGHGGGGGGGGGGGCFGHHHHHHHHHHHHHHHHHGHHHHGGGDGGFGGFGGHHHHHH>FHHHFHGHGHHGHHHGHHBA<CGFHHHHHHHHHHGFHHGDDEGCEGGGGEEFBFGGGGFGGGB0CFF:FFFFFBBFFFFBFEFA.BFFFEFFFBF/BF/FFEFFBFFF
+@M01368:8:000000000-A3GHV:1:1108:16350:22621/1
+TTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+AAAACFFFFFFFGGGFGGGGGGHHHHHHGBGGGFGGGHFGGGGGHHHHHGGHHHHFHGGGGGGHHGFHHHHHGEFHHFFHHGFCEFHHHGFF?GHHEE@ECFHHEGGGGBFFEGGGHFDHHGFG/BFEHHFCDGGGCDEGGGCGFFFHHHFEGHFHHHHGHHDGHHHGGHDED0CE;CFFFFBFF/;CBFFFGG0/FFF0B0:BB?.;BFF0FGFBFFFFFEFE;ADED.;BE.99FAFFFFFFF/;EFF/
+@1:A:M01368:8:000000000-A3GHV:1:1108:21791:23272/1_PolyA:1
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTT
++
+3ABBBFFFFF@FGGGGGGGCGGGHHHHHHHHGHHACGDAGFEEHGGHHGHHHHHHHHHHHGGGGGGHHHHGFHFGHGFDDGFFFGGFGHHFF?FEGHHGGGGGGHHHGFFDHHFGG?HEFGHHGGGDDCGFFC?ECCFGDEFGGGGGGFHHHHHHHEFHFCGHHGEGGGGD.:.A;CECAFFFFBFF/;EFFBFFBFB;;BFFFFBBAA./BFFEBB//BFFFFFFFDFFFEEFEFFFBFBFBBFFFFF.
+@M01368:8:000000000-A3GHV:1:1108:23314:26089/1
+ATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTG
++
+BBBBBFFF?FFAGFBFGGEGGGGHGHHFHHHGHHGFGGFHHHHHHHHFHHFHHGHHHGGGGGHHHHFFEHHHGGGGGGHFHGEEGF3FEFGHHHHHFFDEEEEHHHGEEGGGGGHFGGDADGFFFFFHHFGHHHFGBHGHHGBCEHDEDDGADCFFHHHGG/:GCCCGHFGHFFGG0CGFGF.FB/9;BFBB0FFBFG0A-..;C:E/.A9.FFFFFFFF9BFFFFFFBFBBB./:BFFF/F;AA?F////
+@M01368:8:000000000-A3GHV:1:1108:25084:18127/1
+TTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGAGATAGACCTGTGATCCATCGTGATGTCT
++
+CCBBCFFFFFFFGGGGGGGGGGHHHHHGHHHHGFGGFHHHHGHHGGFHEHHHCGGGHBHHHHHHFHHGHHHHGGHHGGHGGGHHHEFHHHHEHGHGGGCFHFHHHHHHHHHHHGHEFGDEGGGHFHHCGGHHGGGGGFGHHGGEGDFHEGG/?GFHGHDGGGGGHHHHADFGGGGGEGCGGGEFGHHFEBFFGGG?GGGGEGGFEFAA?.0:A0;BFFFBFF/;9BFFFFEFF9FBFFB/F/.;FFFF/BB
+@2:A:M01368:8:000000000-A3GHV:1:1108:7626:10048/1_PolyA:2
+ATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTG
++
+CCCCCFFFFFFFGGGGGGGGGGGHHHHEFEFHHGGGGGGHHHGEF?GGGGGGHHHHHHGGGEGEHHHHGGGGGGGGGGGGGGHHHHHHHHHHHHFFCGHGHHHHGG/BFGDGG2FFHFHGHH0FHFGFHHHHFFHHHHHHHGG<FHHHFGHHGGGGFHHHGGGGGGHGGHGGGHHHHHHFGGGGGGGFFFGGFGGBFGGGGGGGGGGGFGFFFCFFDFFFFFFFFF;./;AAAFFFFFFAFABBFFFB/
+@M01368:8:000000000-A3GHV:1:1109:11270:12255/1
+AATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAGGTAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTT
++
+CCCCCFFFFFFFGGGGGGGGGGGGHHHHFFFHHHGGGFGGFFHGEGCHHGGGGHHHHHHGGGGGGHHGHGGGGGGGGGCEGFCHHHHHGFHFHHHHGFHHGGFHGGGFD/EFGEFFDGFHHGEFCEHFFGHHHGHHHHHHHHHGCGHHHGGFGHHHHGHEHHCFFADGHHHD?CG.CGHBCBFBFFGGFFFGFFFFF.CFBFBCFFFFGFFFFFGGGFFFFFDFAFFFFFF-@DBFFFFBFD---.;BAA.
+@M01368:8:000000000-A3GHV:1:1109:19224:11655/1
+AAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGCATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCTGTCTCTTATACACATCTCCGAGCC
++
+BBB@A4FFFBBBGGGGGGGGGGHHHHHHHHFHHHHGFGHGGGFFAGFHHHFHHHGHHHHHHHHHHHFHGGHGHHGCFFGHHHGHHHGHHFHGGH3BFFGHHGHGEFFH/EG@-CFGGCC@-;BD?FGGGGGG??FGDAGDFFFFEFF@BAAFEFFBFFFFF?FD9BBFFFF/FFFFBFFFFFFF?FFBFFFF/FBBFFBFFFE?F;@B//AFFFFFFFFF//;BFFEF.BFFFB/;F/99/FBFFBDCF;B
+@M01368:8:000000000-A3GHV:1:1109:21978:9490/1
+GGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCAGTT
++
+?A3AA?DFFFFFGGGGGGGFFGHFGCEGGFHHHHHHHHHGHCBGFEGGHHDEGAFGHGHFGDGBCGHHHHHFHHGHHHHHHHGHHHH1E?EGGGHHHHFGFHFHHHHHEDHHGHH@GGHGHHCGG?CFGFGGGGGFGB.BFGGFFGGFFFBDDBFFFFFF9-;DEFFDFBFFBB.EFF;BFBFFFFFFFFFFFFFFFFFFFFFFFFF/B9/FFFFFFFAFFFF--99AFFFFFFFA;;;FF..9//;/;;/
+@1:A:M01368:8:000000000-A3GHV:1:1109:22910:4079/1_PolyA:1
+TAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTCCACTTTAGCT
++
+CCCCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHHHHGGGGGHHHHGGEHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGFHHHGGGGGGGHGGGGGGHHHHHHHHHHHHHHHHHGGHHHGGHGGGHHGHGHHHHHHHGFHHHHHHHHHHHHHHHHHHGGHHHHHHHHHHGHHHHHHGGGGGGGGGGGGGGGGGGGGFFGGGGGGGGGGGFFFFFFFFFFFFFFFFFFFCCDFFFFFFF0BFFFFFFF
+@M01368:8:000000000-A3GHV:1:1109:24217:19077/1
+AAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGCCTTTGATTCCTGCCTCATCCTATTACTGTC
++
+>AAA3BDFFFFDGBFFEEGGGGHHGHFHHCFHGHGHHHGF3BFGFHGFEFHFHGH3EGFC1EEGBFGBHFGGFFHHHGHFHGHHGHGGHCEHEBCFF3ED3@GH4FDEG12FFHFFHG/G3FGA/@EFEFCG33FFGBBGHFHH/?BFBGFGFAGC2C/@-;@-;BFFEFADF?DFFFFFF?;AFFA;AD;..FEFFA--;9;D.9BFFBE?;.;///://///99//BB/9;F./B//BBFB9////99/
+@M01368:8:000000000-A3GHV:1:1109:25237:11722/1
+CCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATATCGTATGCCGT
++
+AABBBFFFFFBBF5BGGFGABGHGGAEFGFHHHHFHCHFHHBFGGGEHBGGHFFFFGFAEF5FHH?EGGF5AEG3?EBFHD?C/EFHFFEGEE?CFGGGHHFHB3EEFG?EEGHCFGGGGGGGEC<CDFHHHHHE.FD11FFAGBGD.DGHEA<.<<0<EHAHCFHHF./;CC0GFH0::0CFGG0FBFD;9/90BFF0CBBFGB09;B:0;CFF0.-;@AFEEF--;AFFBF/99D-;.//.../9;B-.
+@M01368:8:000000000-A3GHV:1:1109:27103:7153/1
+GTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGCTGTCTC
++
+33>A?FFFDFBFGCG4EGFG??GACFGGHFHCFHCHBECDEFCEGHHHHHFFGGF3AFFHHFGEGCGHHGEHGFGHHEGG?EFHHH?EGGHHGGGGHHHHHHEGGGGGHFHHGFDDGGACFCC@?/FDDGHHHGHEFFHHH0FDHHFFEDCD.<GGEHGF0CHHHF/CAGC000CCGFHFGFGFFG?:CB990;F09;FB0BBGGGGGG?;A9EBDEFA///;FF/:F?BFBBFFBFFFF///;/9B;///
+@M01368:8:000000000-A3GHV:1:1109:8763:7859/1
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGCTTTATGC
++
+BABAADFFFFFFGGGGGGGGFBGFGHHFBHHHHGGHHGGEHGDHHHFGHEHHHHGHHGGGGAGHHFBHHGHFHHHHHHHHGGGCEFGFFFFEHHH?FFG1FFHHFEGGGHGFEEHHHHHGGGFGGGHHHHGGGGG/C/FG-<A<GFHHFFCGHHFHGE0<<CGHHHGCHG.CCCCCE00BBFGFFG.BB0FFBFBCF0;CBFFFEEGBBBFFBF/FFF9BF/9BAFFD9AFEDAA.A/BFFFFFFFFFEB/
+@M01368:8:000000000-A3GHV:1:1110:12808:18367/1
+AATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCCTG
++
+BBBBBFFFFBBFGGGGGGGGFGFGHHGGGGGHHHHHHHHGFHHGEGGGHHGFGHEEGGHHHHGHHGFFHHGGGGGHHHHGHGHGHHHFGGFHHGGGGGHHFFFGGHHHE?@EGGHFHEGGGHHGGGGHGEFHHGD?/>CFHHGDFGGGGGEFGC?EGHHHB0CGHHGCGHHHHBEHGHH.::ACA;FECFGGGGGFFFEFGGGGGGGFFBBBFGBFFFEFFFFBFFFFFFBBFBFFB9..AF?FFFFFFF9
+@M01368:8:000000000-A3GHV:1:1110:14751:26540/1
+TAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACTGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGTTGTGCACGCGATAGCATTGCGCGACGCTGGCGCCGGCGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTG
++
+AAA?1CFFFFADGEEGFGB1112DGDGHGFGHHCG/ECEBGGHDFGHHFHGHEB1BCGFFE2EGHHGHFFFHHBFFHEFCGGHHFHHHHH111BFFHGHEHBEHGGECEFHGFHFGGDBBGHHBHHHH0GH22FGHGFFFH1BFCG0F@FGG11@GDHFG1D/1FGFHH/FCG.>0><-<@CCFFG.CC-@C?C9FFF0C---;------;9----9-9@-AAFF9B9---9-/;B9BF/9BB//B/;///
+@M01368:8:000000000-A3GHV:1:1110:15519:10008/1
+CTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACC
++
+BBBBBFFFFFFFGGGGGGCBGGE?GGGHHHHHGHHBEGGHHGGGGGHHHHHHHHHHHGGHHHHGFGGGGHGHGCFGHHHGGGCGGHGHGGGGGHFGGGHHHHHHGCEFGGHHHHGGGGGGGHGG/CEGHHHHGFHHHGFHHGFFHGHGHFGGEGFDDGGBCGHHGFHH/CHHHHGHGHF0CFGGGGGGGFFFFFBFFFFFFGFFGGF?DGEDEEFEFFFF?FFFFFFFFFFFFFFFBFFF.BFFFBFBBA;
+@M01368:8:000000000-A3GHV:1:1110:16559:7507/1
+CATTCAATTGTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAACTGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATC
++
+ABBBAFFFFFFFFGGGGGGGFGGGGAGHHGCHHGHHHHHHHHHHHGHHGHHHHHHHHHHHHHHHHFGGGHHHHHHHHBDHHHHHGGHFEEGHGGHHHHHHHGHHHEHFGGGGGGHHHF33FGHHG3GDDGH//EEGHHFFBF?GHHFCC@DGFCGGB?DGHAFGGHHGFH0E??<@DGHGGCFGGF?DGGGFFGGGGGGGG.C/0BBF?FBBEGG0FFF.AA9;B9/E////99;;:.//:FFFFBBF//9
+@M01368:8:000000000-A3GHV:1:1110:16700:6843/1
+AAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCTGTCTCTTATACACATCTCCGAGCC
++
+BBBBBFFFFFFFGGGGGGGGGGHHHHGHHHHHHHHHHHHGGGGGHHHHHGGHGHGGGGGGHHHGFFGHHGGGGHHHHHHCGG@FGHFHFEGGGGGGHGGGGDGHHHHHHHHHHHHHHGHHGHGHHGGGGGCGHEHGHHHFHHHFF.DGHHHHHHGHHHHHHGFGHGCGHGHHHHHHHHGHHHCD?:A::FCDGEGFGFFBFGBFGGGF00CBFFFF/BFBFFFFAE.FBBFBFFFFB/BFFBFFF/ADCAD
+@M01368:8:000000000-A3GHV:1:1110:18014:7856/1
+ATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGCAAAAAAAAAATAG
++
+AABBBFFFFFFFCGGGCGGGGGGHHHHHGFHHHHHHGHHHGGGGGFHHGHFGGHHHGGFGGGHHGGGGGHHGGGGHGGHHHGGGGGGHHGHGDGGGGGGGGB/A<GFHFHHHGHBBGFEGGGGHFFFEF/EEGGHGGFEHFHHBA.<ADFFHFHB/CCGHFEFHHGHGEFFGGGGGFFFGGFGFFBFFGGBFGG??DGG?@9-ADFFFFB/@BD;./BFE?BFE/>99FE//BBFFF.9/FF?DA=@9./9
+@M01368:8:000000000-A3GHV:1:1110:23303:11846/1
+ACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGTGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTC
++
+3ABB?FAB?DAAGGGFBGGBB5AFFFGFHHGGGEGHHHFHHF3EGFHHHHEFHHGGHHHGH3EFHHHHHBDGHHE?ECHGHGHHHHHHFHHHGHHHHHHHGGHGGFHHHFHHGFFHHFEGFHHHHHHEHHFDAGHHHH/BDDFGGH1FDBGHHHHHHHCGHHHFH?0CGCF>CC=@--AFBFFB?=BFDFFF//FDB;-9A-AD-.A.A=?-9-:B/AEB/BFF.A;DDFFFBBFFFF/BBFFFFBFF9B;
+@1:A:M01368:8:000000000-A3GHV:1:1111:13195:14562/1_PolyA:1
+ATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACACATCTCCGAGCCCACGAG
++
+ABAAAFFFFFFFGGGGGGGGGGGHHGG4FDFGFGGCGGGHGHG?EGHEGFFDHFHHHHGGFE@EHHGEEEGFCCEFFGFG/EHHHHHBFBGGHFHFHEHGHEFGGGED/EFDEFFEHHBGHHCFFFDFGGHHGFFFHHHHGFG>0<0DGGFHBGHFBDFGHGFFGGAGHHGCGBHFFHHHFFFBFGGGGF/:FFFCB9F9FF0FEFE?FF0BED-D.//BF9//BBFF/BFFFEFFFFED-DCFF?.:BF
+@M01368:8:000000000-A3GHV:1:1111:14287:20817/1
+GCCAACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTCATCGCACCTACGTTCACTATTACAGGCGAACATACTTATTAAAGTGTGTTAATTAAT
++
+>>A3>AAAACFFFGFGFGGGGGHGHHHHHHHGGGGGHGHFFCGHHGBGHFHHHHAGHHHHEHHAGFFEHEAE?GHHHHEGFFFDGHGHBFFHFHHHGHGHGHBECG@@@EHGGEGCGGGGFFGGGG?BGGGGGG.-C.FEDCFFFEFFFAF/99BEFA.:9BFB/9FFFEFFFFFFEFFF/FBBFFFFFFFFFFFB//;.@@//;DFFFF//BBFFFBF;A;DF=>B//;9B//B/;/;9//9//;B/:B9
+@M01368:8:000000000-A3GHV:1:1111:23624:14516/1
+GTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGGGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAG
++
+3>3AAFFFFFAFGGGGGGGGBGHHHHHHGGHGGHEHGHADFHHHHEGGGHBGHFFHHEHHGHFHGG5FBEEGEGHHHGHHHEFDGHHFFGFGGHHGHHHGHBHGHFHFHHGGGGFCFBGFGE?GFBECEGDGHEHGDGCGHGC/DF@GHGFFCGGGGFFFFDD?@C@GFEC?-ADHFFHBGHFBHFG0CC//.;B0/CA.;AA.;@.AB/9BB/A/.AFFFE/BFFF///9B/FBDE9/;99/B/BFFEF/
+@M01368:8:000000000-A3GHV:1:1111:7437:24508/1
+ACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTGTCTCTTATACACATCTCCGAGCCCACGAG
++
+CBCCDCFFFFFFGGGGGGGGGGGGGGHHHHHHHHHHHHHHHHGGGFFEHGGHHHHHHHHHHHGHHGGGGGHHHHHHFHHHHGHHHHGHGGGGGHHHHHGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHGHHGGGGGGGHGGGGGCGHHHHGHHGHHHHHHHEDHHGHGGGGGD;BEGGGFFGGGGC:CFGGGGGGGGGFGGGFFFGFFFFF;FFF;BFFFFFFFFFFFB:FFFFD=CAEEEF>-
+@M01368:8:000000000-A3GHV:1:1111:8665:25542/1
+TCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTGTCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCG
++
+AA3AAFFFFFFFGGGFGFFGGGGHGH4AGGGFHHCGEE2FGHHHHHHHHHHGFHGF53FHEGGFAF5CFHHGGFGHFHHGGHHHCHHHHHHHFHHGH?EEEG1FFFEHHFHFGGHHGG?F4FBGHGHCHEF0//-9--;0CFGG?@BGDGFFFFEFBBBDA?FFBFFFF=B;-9.AA9EFFFF/;9BD.//;9/9/B:/:BFBFFBFFF/B:BFF//;/B/FFFBFF.A-BFFFBA/F//BFFFBF/;/A-
+@1:A:M01368:8:000000000-A3GHV:1:1111:9655:13916/1_PolyA:1
+GGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGCGGTGTCCACGCAATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTG
++
+1>>1AAFFFFFBGGFE1EEEEGGHGHHH2FGHHHFGFGHGCFGGGEFHGGEGGHHHHGHEFBFEGHHHGHHBEHHHHGHGFHHHGGGGHHEGGGGHHHGFHGHHHH1FHHG?G/AGF1GBFGEFFHF2FDD0FG<GDHBFDGFFCGH//B//?0GFFGFGGHHHFHFB.=1FDFB?FGH.C/.-:::CH0;CAB@-.;0CGFFFGG--9.A@GB>--99@=---AAABA-BF/B?A@F-9BBFF//BB/9
+@M01368:8:000000000-A3GHV:1:1112:10272:7828/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTT
++
+AAABABBBBBBFGGGGGGGGGGHGHHGHGHHHHHHHHHGHHHGGHDGHHHGGGGHHHHHHHHHHHHHHHFHGHHHHGGHGGHHHFHHHHHCGHFFHHHHHHHHHHHHHGHGEFGAEEEEHHGHHGHGHHHHHHHGHHHHHHGHGHFFBC/BA?BGGGFFFFFFFFFFFFFFFC-@DDFFFFFFFEFAFFFFFFBFBFFFFFFFFFFFFFFFFBFF->@FFFFFFFFFFBFBFAD--.99;A?////:.9A.
+@M01368:8:000000000-A3GHV:1:1112:9832:16531/1
+CTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGGGCTGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCTTGAAGTAGGAACC
++
+AABABFFFFFFFF4GGGGEBGEFGHGGHGHGHHHGGHFBGFGGGGGHHEFHGEHFHFHEHHHHHGCGGGHFHHCFGHE@1EEEFFGB?EEEEHBGGGCHHGHHBEE@>EAHHFAEBDGGGCEFF?CEGFFHHHHHFHHHFHGHCGCAHHF<..C.D=0CD.GFHHHG.CAGHC:CHB0GGGFFB0:CFA.A-;9.;000CBBFFBFGA.9AA;A;EDDE.ABBFFFF9;BEFFF/BF//9/B//9:B//..
+@1:A:M01368:8:000000000-A3GHV:1:1112:9832:6701/1_PolyA:1
+CGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGG
++
+AABBBBFFFFFFGGGFGGGGGGHHHGGHGGHHHHHHHHHHHGHHGGGGGHHHHHHHHHHHHHHHHHHGGCGDHHHHFGGHHHGGGGGFGGHGGGGHHGGGGHHHHHHGGGGGGHHGGGGDGGFGHGGFCDCHHHHGHHHHGHHFAGFGGEHFGEG.C<EGCECEFCFFHBGHE:GHHGFF0FFFB0CFGGGGAGFFF0;;FFGGGFFGFFCDD.DEFBEDD?9FFFFFFFFFFFFFFF/B./FB///;BF
+@M01368:8:000000000-A3GHV:1:1113:13532:8618/1
+GGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGCTACAGTTCACTTTAGCTACCTCCAAGTGTTATG
++
+AA?AAFFFFFFFGGGGGFBFGGGGGGH5GHFEDHHGGGGCGFBGH?AEEHFFEEGHGHHHHGGG?0EHGHHGGGGGC?GEE/EE?GHHHGBHFHHHHHHGHHGHHHGGGCG/A@<FGGHHHHHHHFF/GFDGHHHHHHGFFFGHGGHABGHFHHHHHFHEGDGHGDDEEHHBEDDEGFGHGBFFBFFEGGGEFGFGFB000;F0F;FGGEGGEFFF;-.9//B///B9FFFFF/BFFB/:.BB//;FBFFF
+@M01368:8:000000000-A3GHV:1:1113:21679:18011/1
+GATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGAGGGTGTGCACGCGATAGCATTGCGAGACGCTTGAGCCGGAGCACCCTATGTCGCAGTATATGTCTTTGATTCCTGCCTCTTCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAACTGTCTCTTATACACATATCCACGCCCACGAGACTAAGGCGAAGTTCATT
++
+AA>1>11F1D1DDFFFFGGG1FH3GHGHGHGHFHEC?EC0B1FBGFB1GHHH21AF2HH2FEGEHAE10AAE/>/FFHE?/E/?E1@EFFH?E@/EGGG//B11B//<@@C0F/<0<FFDGGCC?FF221<BDD11@<11@DDCGEF1<111F1<F1FBGHGHCF-CHHFA./</0CGHF<0CC/;C-:-;;09;FFBFBBFFBC0FFFGGFC0009C00090/-:--9--;-;AFFE;/99-9--/;///
+@M01368:8:000000000-A3GHV:1:1113:25528:14016/1
+CCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGG
++
+>AAAAFFFBFFFGGGGGGGGGGHHFHGHHHHGHHHHHHHHHHHGGGGHHHHFHHHHFHGHHHHGAFFEFHEGHHHHHHHHGHEHHGGFGGGHHHHHHFHHHHHGGHHHHGGGGGHFHHFF?HHGGFECEFFGHFFGFHGECDGHGBGFHGDF@@?CGFHCEGGGFD.CCC?EGHBHHHFHHFBCFFGEB/CEGGGGDAA.90C9CEBFGGBBF/9.9FBFFFBBFF//99FFFFEABF//99FFEFFFBFF
+@1:A:M01368:8:000000000-A3GHV:1:1113:5741:16959/1_PolyA:1
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+ABBBBFFFFFFFGGGFGGGGGGHHHGHHGGHBGHGAGFFCAFGHGFFGHHGFHHHHHGGGGGHGHHHHHHHHE3BFFHHHGG0EDF@GHFFGGGHGGGGGGGGGGGGGHHGGEEFHGFHHDDG@DGGGHHGDGGGGGHGG?CF?HHGHHHGHGHHHFFHGGGHHHHGGCD.;0<C;CGGGGEFF/.;0;FFFBF/0;0CFGFFB..9B/;0CBFFBBFFFFBAC?DED9;B9AD;.FFFB/B/;FBA/B/
+@1:A:M01368:8:000000000-A3GHV:1:1114:10130:11959/1_PolyA:1
+CGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTCTGATCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGCAACAAACACACATCCAG
++
+>A33>FFFFFF@FFFGGGGFGGD4EGGGGGHHGFFGHFGGHHHFEFHECFHHHEHGAGBCCGCCEGGHGHEGFBFHFHHHHGGGHFHGHEGGGFEGEGG??@DBGHGGC-@FFGHFHFHB-??DA-DD@9:BEBG@B?E?A.ABBFBFA??F.FF/BFFB/B9B/9;BF9FF9FFFFFFFFFFFFFF?BB?;9EE;-;DDB9//;B-B@;ABFFEFFFF/-.9A.;//9/BF./B/..9.9:.../////
+@M01368:8:000000000-A3GHV:1:1114:14540:5315/1
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGGGGGCTATTTAGGTTTTT
++
+AABCCFFFFFFFGGGGGGGGGGHHHHHHHFHHHHGHHGHHGGGHGGHHHHHHHGHHHHHHGGGGGHHFHHHFGHHGGFHHHHHGGGGGHHHGHGGHHHGGGGGGHGHGGGGHHGGGGHHHHHEGDDFGFFFHHGGGGGCDAFCFGFDHHHHGGHGHHHHHHBCGEHHHHGGHG.ACGEHGG0CBFFF:A;BB0;09CGF00CFFFE0AA?//CFFFFFFFFFFFFFFFBEF;A.-=A--:BBFB90;;FE.
+@1:A:M01368:8:000000000-A3GHV:1:1114:15066:16302/1_PolyA:1
+TAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAACGGTTGTTAATTAATTATTGCTTGTAGGAC
++
+BBBBAFFBDFBFBGGGGGFGGGBGFFFHGFHHGFFFHGHHHGHHHHFFHHHGHGC?AEFFHEFBFFFGHHHHH1FDGFFHGHGHFEGCGC-<<AHHHGGGGGGGFHH0GHFCCCADGGG?.9/A-???DGGFFF.9F9/EE-;;BBBFFBFFFFFFFFFEFFFFBFFBBFFFFF/BFFBFFFFF-DBFFF;/BFF//BB//9/BEA---9:BFFFFFF/F/.;.:@9.BBFF/;BFF/;/////9/////
+@M01368:8:000000000-A3GHV:1:1114:16639:15258/1
+CCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGCGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTCCAATATTACAGGCGAACATACTTACTAAATTGTGT
++
+11>>ABFFFFFFGGCGC1BBF1GHHHBHHHHGFHGH1A100AA/GGEHGFBAA1FFD2FHHHHECG2F1BB/E0FC/A>EE/FGGFGEF1EGBBEHHCGGGHBGEHFHE0B?E--;C?CCGGG@A@GBFBBBB09?@??A-AB--ABE@=-=-9AE9A;FFFFFE=9-//;//;9FF/////;;///9B///;/B////9FFBB;--A@-;/9;9-:-/;;FFFE9BF?@;-9-99/B9F/://///99/;
+@M01368:8:000000000-A3GHV:1:1114:2404:13066/1
+TCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCTGTCTATTATACACATC
++
+CCCCCFFFFCFFGGGGGGGGGGHHHHHGHHHHHHHHHFFHHHHHGGGGHHHHHHHHFHHHHHHFGGHHGGHGGHHHHHHGHHFHHHHGGGGGGHHHHHHGHHHHHHHHHHGGGGGGGHH?FGHHHGGGGGGHHGGFGGHHGGGGHHHHHFGGGGFGHGHHGGGGGGGHGGGEGGHHGHHHHHHHHHGFBFFDA0FGGGFFGG0:EFGGGGGGGG;AEBF0B0BFFBFFFFFFFFFFFFFFFFFFFFFEFF0
diff -r 313e04fe07cd -r cc01cbc4e7f7 trim_galore.xml
--- a/trim_galore.xml	Tue Jul 30 06:26:22 2019 -0400
+++ b/trim_galore.xml	Fri Oct 08 09:57:12 2021 +0000
@@ -1,50 +1,10 @@
-<tool id="trim_galore" name="Trim Galore!" version="0.6.3" profile="17.01">
-    <!-- Wrapper compatible with Trim Galore! version 0.6.3 -->
+<tool id="trim_galore" name="Trim Galore!" version="@TOOL_VERSION@+galaxy@VERSION_SUFFIX@" profile="20.01">
     <description>Quality and adapter trimmer of reads</description>
     <macros>
-        <macro name="adapter_trimming">
-            <conditional name="trimming">
-                <param name="trimming_select" type="select" label="Adapter sequence to be trimmed">
-                    <option value="">Automatic detection</option>
-                    <option value="--illumina">Illumina universal</option>
-                    <option value="--nextera">Nextera transposase</option>
-                    <option value="--small_rna">Illumina small RNA adapters</option>
-                    <option value="user">User defined adapter sequence</option>
-                </param>
-                <when value=""/>
-                <when value="--illumina"/>
-                <when value="--nextera"/>
-                <when value="--small_rna"/>
-                <when value="user">
-                    <param name="adapter" type="text" value="AGATCGGAAGAGC" label="Adapter sequence to be trimmed off">
-                        <validator type="regex" message="Adapter sequence must contain DNA characters only (A,C,T,G or N)">^[ACTGNactgn]*$</validator>
-                    </param>
-                    <yield/>
-                </when>
-            </conditional>
-        </macro>
-        <macro name="paired_adapter_trimming">
-            <expand macro="adapter_trimming">
-                <param name="adapter2" type="text" optional="True" value="" label="Adapter sequence to be trimmed off read 2">
-                    <validator type="regex" message="Adapter sequence must contain DNA characters only (A,C,T,G or N)">^[ACTGNactgn]*$</validator>
-                </param>
-            </expand>
-            <param name="trim1" type="boolean" truevalue="--trim1" falsevalue="" checked="False" label="Trims 1 bp off every read from its 3' end." help="" />
-            <param name="three_prime_clip_R1" type="integer" value="" optional="True" label="Remove N bp from the 3' end of read 1">
-                <help>Instructs Trim Galore! to remove N bp from the 3' end of read 1 after adapter/quality trimming has been performed.
-                    This may remove some unwanted bias from the 3' end that is not directly related to adapter sequence or basecall quality.
-                    (--three_prime_clip_R1)</help>
-            </param>
-            <param name="three_prime_clip_R2" type="integer" value="" optional="True" label="Remove N bp from the 3' end of read 2">
-                <help>Instructs Trim Galore! to remove N bp from the 3' end of read 2 after
-                    adapter/quality trimming has been performed. This may remove some unwanted bias from
-                    the 3' end that is not directly related to adapter sequence or basecall quality.</help>
-            </param>
-        </macro>
+        <import>macros.xml</import>
     </macros>
-    <requirements>
-        <requirement type="package" version="0.6.3">trim-galore</requirement>
-    </requirements>
+    <expand macro="requirements" />
+    <expand macro="xrefs"/>
     <version_command>
         trim_galore --version
     </version_command>
@@ -92,6 +52,9 @@
 
         trim_galore
 
+        ## according the develpers 4 cores could be a sweet spot, anything above has diminishing returns
+        --cores \${GALAXY_SLOTS:-4}
+
         ## we only support fastqsanger
         --phred33
 
@@ -177,6 +140,18 @@
             --dont_gzip
         #end if
 
+        ## Trimming settings
+        #if $trimming.settingsType == 'custom'
+            #if $trimming.hardtrim5
+                --hardtrim5 $trimming.hardtrim5
+            #end if
+            #if $trimming.hardtrim3 
+                --hardtrim3 $trimming.hardtrim3
+            #end if
+            $trimming.clock 
+            $trimming.polyA
+        #end if
+
         ##  Trim Galore is finished, rename the output if compressed
         &&
         if [ -f input_1_trimmed.fq.gz ] ; then mv input_1_trimmed.fq.gz input_1_trimmed.fq ; fi
@@ -188,12 +163,37 @@
         if [ -f input_1_unpaired_1.fq.gz ] ; then mv input_1_unpaired_1.fq.gz input_1_unpaired_1.fq ; fi
         &&
         if [ -f input_2_unpaired_2.fq.gz ] ; then mv input_2_unpaired_2.fq.gz input_2_unpaired_2.fq ; fi
+        &&
+        if [ -f input_1.clock_UMI.R1.fq.gz ] ; then mv input_1.clock_UMI.R1.fq.gz input_1.clock_UMI.R1.fq ; fi
+        &&
+        if [ -f input_2.clock_UMI.R2.fq.gz ] ; then mv input_2.clock_UMI.R2.fq.gz input_2.clock_UMI.R2.fq ; fi
+        
+        ## Rename hardtrimmed files
+        #if $trimming.settingsType == 'custom'
+            &&
+            if [ -f input_1.${trimming.hardtrim5}bp_5prime.fq.gz ] ; then mv input_1.${trimming.hardtrim5}bp_5prime.fq.gz input_1_hardtrim.fq ; fi
+            &&
+            if [ -f input_2.${trimming.hardtrim5}bp_5prime.fq.gz ] ; then mv input_2.${trimming.hardtrim5}bp_5prime.fq.gz input_2_hardtrim.fq ; fi
+            &&
+            if [ -f input_1.${trimming.hardtrim3}bp_3prime.fq.gz ] ; then mv input_1.${trimming.hardtrim3}bp_3prime.fq.gz input_1_hardtrim.fq ; fi
+            &&
+            if [ -f input_2.${trimming.hardtrim3}bp_3prime.fq.gz ] ; then mv input_2.${trimming.hardtrim3}bp_3prime.fq.gz input_2_hardtrim.fq ; fi
+            &&
+            if [ -f input_1.${trimming.hardtrim5}bp_5prime.fq ] ; then mv input_1.${trimming.hardtrim5}bp_5prime.fq input_1_hardtrim.fq ; fi
+            &&
+            if [ -f input_2.${trimming.hardtrim5}bp_5prime.fq ] ; then mv input_2.${trimming.hardtrim5}bp_5prime.fq input_2_hardtrim.fq ; fi
+            &&
+            if [ -f input_1.${trimming.hardtrim3}bp_3prime.fq ] ; then mv input_1.${trimming.hardtrim3}bp_3prime.fq input_1_hardtrim.fq ; fi
+            &&
+            if [ -f input_2.${trimming.hardtrim3}bp_3prime.fq ] ; then mv input_2.${trimming.hardtrim3}bp_3prime.fq input_2_hardtrim.fq ; fi
+        #end if
 
         ##  Trim Galore! run is finished. Move the report files to the proper place
         #if $params.settingsType == "custom" and $params.report:
             &&
             cat ./*_trimming_report.txt > '$report_file'
         #end if
+        && ls -lah
     ]]></command>
     <inputs>
         <!-- Input Parameters -->
@@ -226,7 +226,7 @@
         </conditional>
 
         <conditional name="params">
-            <param name="settingsType" type="select" label="Trim Galore! advanced settings" help="You can use the default settings or set custom values for any of Trim Galore!'s parameters.">
+            <param name="settingsType" type="select" label="Advanced settings" help="You can use the default settings or set custom values for any of Trim Galore!'s parameters.">
               <option value="default">Use defaults</option>
               <option value="custom">Full parameter list</option>
             </param>
@@ -261,7 +261,7 @@
         </conditional>  <!-- params -->
 
         <conditional name="rrbs">
-            <param name="settingsType" type="select" label="RRBS specific settings">
+            <param name="settingsType" type="select" label="RRBS specific settings" help="You can use the default settings or set custom values for any of Trim Galore!'s parameters.">
               <option value="default">Use defaults (no RRBS)</option>
               <option value="custom">Full parameter list</option>
             </param>
@@ -274,35 +274,84 @@
                     label="Screen quality-trimmed sequences for 'CAA' or 'CGA' at the start of the read and, if found, removes the first two basepairs" />
             </when>  <!-- full -->
         </conditional>  <!-- params -->
+        <!--Trimming options-->
+        <conditional name="trimming">
+            <param name="settingsType" type="select" label="Trimming settings" help="You can use the default settings or set custom values for any of Trim Galore!'s parameters.">
+                <option value="default">Use defaults</option>
+                <option value="custom">Full parameter list</option>
+            </param>
+            <when value="default" />
+            <when value="custom">
+                <param argument="--hardtrim5" type="integer" min="1" optional="true" label="Hard-trimm 5' ends" help="Instead of performing adapter-/quality trimming, this option will simply hard-trim sequences to N bp at the 5'-end. Once hard-trimming of files is complete, it will exit" />
+                <param argument="--hardtrim3" type="integer" min="1" optional="true" label="Hard-trimm 3' ends" help="Instead of performing adapter-/quality trimming, this option will simply hard-trim sequences to N bp at the 3'-end. Once hard-trimming of files is complete, it will exit" />
+                <param argument="--clock" type="boolean" truevalue="--clock" falsevalue="" label="Mouse epigenetic clock mode" help="In this mode, reads are trimmed in a specific way that is currently used for the Mouse Epigenetic Clock"/>
+                <param argument="--polyA" type="boolean" truevalue="--polyA" falsevalue="" label="Remove polyA tails" help="This is a new, still experimental, trimming mode to identify and remove poly-A tails from sequences" />
+            </when>
+        </conditional>
     </inputs>
 
     <outputs>
         <data format_source="input_singles" name="trimmed_reads_single" from_work_dir="input_1_trimmed.fq" label="${tool.name} on ${on_string}: trimmed reads">
             <filter>singlePaired['sPaired'] == "single"</filter>
+            <filter>trimming['hardtrim3'] == '' and trimming['hardtrim5'] == ''</filter>
         </data>
 
+        <data format_source="input_singles" name="hardtrim_reads_single" from_work_dir="input_1_hardtrim.fq" label="${tool.name} on ${on_string}: hard-trimmed reads">
+            <filter>singlePaired['sPaired'] == "single"</filter>
+            <filter>trimming['settingsType'] == "custom"</filter>
+            <filter>trimming['hardtrim3'] != '' or trimming['hardtrim5'] != ''</filter>
+        </data>
+
+        <!--Trimmed reads paired collection-->
         <collection name="trimmed_reads_paired_collection" type="paired" label="${tool.name} on ${on_string}: paired reads">
             <data name="forward" format_source="input_mate_pairs['forward']" from_work_dir="input_1_val_1.fq" />
             <data name="reverse" format_source="input_mate_pairs['forward']" from_work_dir="input_2_val_2.fq" />
             <filter>singlePaired['sPaired'] == "paired_collection"</filter>
+            <filter>trimming['hardtrim3'] == '' and trimming['hardtrim5'] == ''</filter>
+            <filter>trimming['clock'] == False</filter>
         </collection>
-
+        
+        <!--Unpaired reads collection-->
         <collection name="trimmed_reads_unpaired_collection" type="paired" label="${tool.name} on ${on_string}: unpaired reads">
             <data name="forward" format_source="input_mate_pairs['forward']" from_work_dir="input_1_unpaired_1.fq" />
             <data name="reverse" format_source="input_mate_pairs['forward']" from_work_dir="input_2_unpaired_2.fq" />
             <filter>params['settingsType'] == "custom"</filter>
             <filter>params['retain_unpaired']['retain_unpaired_select'] == "retain_unpaired_output"</filter>
             <filter>singlePaired['sPaired'] == "paired_collection"</filter>
+            <filter>trimming['hardtrim3'] == '' and trimming['hardtrim5'] == ''</filter>
         </collection>
 
+        <!--Hard-trimmed reads paired collection-->
+        <collection name="hardtrimmed_reads_paired_collection" type="paired" label="${tool.name} on ${on_string}: hard-trimmed paired reads">
+            <data name="forward" format_source="input_mate_pairs['forward']" from_work_dir="input_1_hardtrim.fq" />
+            <data name="reverse" format_source="input_mate_pairs['forward']" from_work_dir="input_2_hardtrim.fq" />
+            <filter>singlePaired['sPaired'] == "paired_collection"</filter>
+            <filter>trimming['settingsType'] == "custom"</filter>
+            <filter>trimming['hardtrim3'] or trimming['hardtrim5']</filter>
+        </collection>
+
+        <!--Mouse epigenetic reads paired collection-->
+        <collection name="mouse_reads_paired_collection" type="paired" label="${tool.name} on ${on_string}: MEC paired reads">
+            <data name="forward" format_source="input_mate_pairs['forward']" from_work_dir="input_1.clock_UMI.R1.fq" />
+            <data name="reverse" format_source="input_mate_pairs['forward']" from_work_dir="input_2.clock_UMI.R2.fq" />
+            <filter>singlePaired['sPaired'] == "paired_collection"</filter>
+            <filter>trimming['settingsType'] == "custom"</filter>
+            <filter>trimming['clock']</filter>
+        </collection>
+
+
         <data format_source="input_mate1" name="trimmed_reads_pair1" from_work_dir="input_1_val_1.fq"
             label="${tool.name} on ${on_string}: trimmed reads pair 1">
             <filter>singlePaired['sPaired'] == "paired"</filter>
+            <filter>trimming['hardtrim3'] == '' and trimming['hardtrim5'] == ''</filter>
+            <filter>trimming['clock'] == False</filter>
         </data>
 
         <data format_source="input_mate2" name="trimmed_reads_pair2" from_work_dir="input_2_val_2.fq"
             label="${tool.name} on ${on_string}: trimmed reads pair 2">
             <filter>singlePaired['sPaired'] == "paired"</filter>
+            <filter>trimming['hardtrim3'] == '' and trimming['hardtrim5'] == ''</filter>
+            <filter>trimming['clock'] == False</filter>
         </data>
 
         <data format_source="input_mate1" name="unpaired_reads_1" from_work_dir="input_1_unpaired_1.fq"
@@ -318,6 +367,36 @@
             <filter>params['retain_unpaired']['retain_unpaired_select'] == "retain_unpaired_output"</filter>
             <filter>singlePaired['sPaired'] == "paired"</filter>
         </data>
+        <!--Hard-trimmed paired reads-->
+        <data format_source="input_mate1" name="hardtrimmed_reads_pair1" from_work_dir="input_1_hardtrim.fq"
+            label="${tool.name} on ${on_string}: hard-trimmed reads pair 1">
+            <filter>singlePaired['sPaired'] == "paired"</filter>
+            <filter>trimming['settingsType'] == 'custom'</filter>
+            <filter>trimming['hardtrim3'] or trimming['hardtrim5']</filter>
+        </data>
+
+        <data format_source="input_mate2" name="hardtrimmed_reads_pair2" from_work_dir="input_2_hardtrim.fq"
+            label="${tool.name} on ${on_string}: hard-trimmed reads pair 2">
+            <filter>singlePaired['sPaired'] == "paired"</filter>
+            <filter>trimming['settingsType'] == 'custom'</filter>
+            <filter>trimming['hardtrim3'] or trimming['hardtrim5']</filter>
+        </data>
+
+        <!--Mouse epigenetic mode paired reads-->
+        <data format_source="input_mate1" name="mec_reads_pair1" from_work_dir="input_1.clock_UMI.R1.fq"
+            label="${tool.name} on ${on_string}: MEC reads pair 1">
+            <filter>singlePaired['sPaired'] == "paired"</filter>
+            <filter>trimming['settingsType'] == 'custom'</filter>
+            <filter>trimming['clock']</filter>
+        </data>
+
+        <data format_source="input_mate2" name="mec_reads_pair2" from_work_dir="input_2.clock_UMI.R2.fq"
+            label="${tool.name} on ${on_string}: MEC reads pair 2">
+            <filter>singlePaired['sPaired'] == "paired"</filter>
+            <filter>trimming['settingsType'] == 'custom'</filter>
+            <filter>trimming['clock']</filter>
+        </data>
+
         <data format="txt" name="report_file" label="${tool.name} on ${on_string}: report file">
             <filter>params['settingsType'] == "custom"</filter>
             <filter>params['report'] == True</filter>
@@ -325,50 +404,50 @@
     </outputs>
 
     <tests>
-        <test>
+        <test expect_num_outputs="2">
             <param name="input_singles" value="sanger_full_range_original_sanger.fastqsanger" ftype="fastqsanger" />
             <param name="sPaired" value="single" />
             <param name="settingsType" value="custom" />
             <param name="report" value="true" />
             <output name="trimmed_reads_single" file="sanger_full_range_results1.fastqsanger" ftype="fastqsanger"/>
-            <output name="report_file" file="sanger_full_range_report_results1.txt" ftype="txt" lines_diff="8" />
+            <output name="report_file" file="sanger_full_range_report_results1.txt" ftype="txt" lines_diff="12" />
         </test>
-        <test>
+        <test expect_num_outputs="2">
             <param name="input_singles" value="sanger_full_range_original_sanger.fastq.gz" ftype="fastqsanger.gz" />
             <param name="sPaired" value="single" />
             <param name="settingsType" value="custom" />
             <param name="report" value="true" />
             <output name="trimmed_reads_single" file="sanger_full_range_results1.fastq.gz" ftype="fastqsanger.gz" decompress="true" />
-            <output name="report_file" file="sanger_full_range_report_results1gz.txt" ftype="txt" lines_diff="9" />
+            <output name="report_file" file="sanger_full_range_report_results1gz.txt" ftype="txt" lines_diff="12" />
         </test>
 
-        <test>
+        <test expect_num_outputs="1">
             <param name="input_singles" value="sanger_full_range_original_sanger.fastqsanger" ftype="fastqsanger" />
             <param name="sPaired" value="single" />
             <param name="trimming_select" value="--illumina" />
             <output name="trimmed_reads_single" file="sanger_full_range_results2.fastqsanger" ftype="fastqsanger"/>
         </test>
-        <test>
+        <test expect_num_outputs="1">
             <param name="input_singles" value="sanger_full_range_original_sanger.fastq.gz" ftype="fastqsanger.gz" />
             <param name="sPaired" value="single" />
             <param name="trimming_select" value="--illumina" />
             <output name="trimmed_reads_single" file="sanger_full_range_results2.fastq.gz" ftype="fastqsanger.gz" decompress="true" />
         </test>
 
-        <test>
+        <test expect_num_outputs="1">
             <param name="input_singles" value="sanger_full_range_original_sanger.fastqsanger" ftype="fastqsanger" />
             <param name="sPaired" value="single" />
             <param name="adapter" value="AAAGAGC" />
             <output name="trimmed_reads_single" file="sanger_full_range_results3.fastqsanger" ftype="fastqsanger"/>
         </test>
-        <test>
+        <test expect_num_outputs="1">
             <param name="input_singles" value="sanger_full_range_original_sanger.fastq.gz" ftype="fastqsanger.gz" />
             <param name="sPaired" value="single" />
             <param name="adapter" value="AAAGAGC" />
             <output name="trimmed_reads_single" file="sanger_full_range_results3.fastq.gz" ftype="fastqsanger.gz" decompress="true" />
         </test>
 
-        <test>
+        <test expect_num_outputs="3">
             <param name="input_mate1" value="bwa-mem-fastq1.fq" ftype="fastqsanger" />
             <param name="input_mate2" value="bwa-mem-fastq2.fq" ftype="fastqsanger" />
             <param name="sPaired" value="paired" />
@@ -378,7 +457,7 @@
             <output name="trimmed_reads_pair2" file="paired_example_pair2_results2.fastqsanger" ftype="fastqsanger"/>
             <output name="report_file" file="paired_example_results2.txt" ftype="txt" lines_diff="24" />
         </test>
-        <test>
+        <test expect_num_outputs="3">
             <param name="input_mate1" value="bwa-mem-fastq1.fq.gz" ftype="fastqsanger.gz" />
             <param name="input_mate2" value="bwa-mem-fastq2.fq.gz" ftype="fastqsanger.gz" />
             <param name="sPaired" value="paired" />
@@ -389,7 +468,7 @@
             <output name="report_file" file="paired_example_results2gz.txt" ftype="txt" lines_diff="24" />
         </test>
 
-        <test>
+        <test expect_num_outputs="7">
             <param name="input_mate_pairs">
                 <collection type="paired">
                     <element name="forward" value="bwa-mem-fastq1.fq" ftype="fastqsanger" />
@@ -414,7 +493,7 @@
                 <element name="reverse" file="paired_collection_example_unpair2_results3.fastqsanger" ftype="fastqsanger"/>
             </output_collection>
         </test>
-        <test>
+        <test expect_num_outputs="7">
             <param name="input_mate_pairs">
                 <collection type="paired">
                     <element name="forward" value="bwa-mem-fastq1.fq.gz" ftype="fastqsanger.gz" />
@@ -439,6 +518,54 @@
                 <element name="reverse" file="paired_collection_example_unpair2_results3.fastq.gz" ftype="fastqsanger.gz" decompress="true" />
             </output_collection>
         </test>
+        <!--Test hard-trim option-->
+        <test expect_num_outputs="2">
+            <param name="input_mate1" value="bwa-mem-fastq1.fq" ftype="fastqsanger" />
+            <param name="input_mate2" value="bwa-mem-fastq2.fq" ftype="fastqsanger" />
+            <param name="sPaired" value="paired" />
+            <conditional name="trimming">
+                <param name="settingsType" value="custom" />
+                <param name="hardtrim3" value="20"/>
+            </conditional>
+            <output name="hardtrimmed_reads_pair1" file="paired_hardtrimmed3_pair1_.fastqsanger" ftype="fastqsanger"/>
+            <output name="hardtrimmed_reads_pair1" file="paired_hardtrimmed3_pair2_.fastqsanger" ftype="fastqsanger"/>
+        </test>
+        <test expect_num_outputs="2">
+            <param name="input_mate1" value="bwa-mem-fastq1.fq" ftype="fastqsanger" />
+            <param name="input_mate2" value="bwa-mem-fastq2.fq" ftype="fastqsanger" />
+            <param name="sPaired" value="paired" />
+            <conditional name="trimming">
+                <param name="settingsType" value="custom" />
+                <param name="hardtrim5" value="20"/>
+            </conditional>
+            <output name="hardtrimmed_reads_pair1" file="paired_hardtrimmed5_pair1_.fastqsanger" ftype="fastqsanger"/>
+            <output name="hardtrimmed_reads_pair1" file="paired_hardtrimmed5_pair2_.fastqsanger" ftype="fastqsanger"/>
+        </test>
+
+        <!--Test mouse epigenetic clock option-->
+        <test expect_num_outputs="2">
+            <param name="input_mate1" value="bwa-mem-fastq1.fq" ftype="fastqsanger" />
+            <param name="input_mate2" value="bwa-mem-fastq2.fq" ftype="fastqsanger" />
+            <param name="sPaired" value="paired" />
+            <conditional name="trimming">
+                <param name="settingsType" value="custom" />
+                <param name="clock" value="true"/>
+            </conditional>
+            <output name="mec_reads_pair1" file="mec_reads_pair1.fastqsanger" ftype="fastqsanger"/>
+            <output name="mec_reads_pair2" file="mec_reads_pair2.fastqsanger" ftype="fastqsanger"/>
+        </test>
+        <!--Test polyA option-->
+        <test expect_num_outputs="2">
+            <param name="input_mate1" value="bwa-mem-fastq1.fq" ftype="fastqsanger" />
+            <param name="input_mate2" value="bwa-mem-fastq2.fq" ftype="fastqsanger" />
+            <param name="sPaired" value="paired" />
+            <conditional name="trimming">
+                <param name="settingsType" value="custom" />
+                <param name="polyA" value="true"/>
+            </conditional>
+            <output name="trimmed_reads_pair1" file="trimmed_polyA_reads_pair1.fastqsanger" ftype="fastqsanger"/>
+            <output name="trimmed_reads_pair1" file="trimmed_polyA_reads_pair2.fastqsanger" ftype="fastqsanger"/>
+        </test>
     </tests>
     <help><![CDATA[
 **What it does**
@@ -452,7 +579,6 @@
  * Trim Galore! can remove sequences if they become too short during the trimming process. For paired-end files Trim Galore! removes entire sequence pairs if one (or both) of the two reads became shorter than the set length cutoff. Reads of a read-pair that are longer than a given threshold but for which the partner read has become too short can optionally be written out to single-end files. This ensures that the information of a read pair is not lost entirely if only one read is of good quality
  * Trim Galore! can trim paired-end files by 1 additional bp from the 3' end of all reads to avoid problems with invalid alignments with Bowtie 1
 
-.. _Trim Galore!: http://www.bioinformatics.babraham.ac.uk/projects/trim_galore/
 
 It is developed by Felix Krueger at the Babraham Institute.
 
@@ -591,6 +717,54 @@
     | Selecting this option for non-directional RRBS libraries will screen quality-trimmed sequences for 'CAA' or 'CGA' at the start of the read and, if found, removes the first two basepairs. Like with the option '--rrbs' this avoids using cytosine positions that were filled-in during the end-repair step. '--non_directional' requires '--rrbs' to be specified as well.
     |
     | *option --non_directional*
+
+---- 
+
+**Trim specific seetings**
+
+* **Hard-trimming mode**
+    
+    | Instead of performing adapter-/quality trimming, this option will simply hard-trim sequences to N bp at the 5' or 3' -end.
+    |
+    | *options -hardtrim5 and -hardtrim3*
+
+* **Mouse Epigenetic Clock mode**
+
+    | In this mode, reads are trimmed in a specific way that is currently used for the Mouse Epigenetic Clock (see here: `Multi-tissue DNA methylation age predictor in mouse`_). Following this, Trim Galore will exit.
+    | 
+    | In it's current implementation, the dual-UMI RRBS reads come in the following format:
+    |
+    | Read 1  5' UUUUUUUU CAGTA FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF TACTG UUUUUUUU 3'
+    | Read 2  3' UUUUUUUU GTCAT FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF ATGAC UUUUUUUU 5'
+    |
+    | Where UUUUUUUU is a random 8-mer unique molecular identifier (UMI), CAGTA is a constant region, and FFFFFFF... is the actual RRBS-Fragment to be sequenced. The UMIs for Read 1 (R1) and Read 2 (R2), as well as the fixed sequences (F1 or F2), are written into the read ID and removed from the actual sequence.
+    |
+    | *option --clock*
+
+* **PolyA mode**
+
+    | This is a new, still experimental, trimming mode to identify and remove poly-A tails from sequences. When selected, Trim Galore attempts to identify from the first supplied sample whether sequences contain more often a stretch of either 'AAAAAAAAAA' or 'TTTTTTTTTT'. This determines if Read 1 of a paired-end end file, or single-end files, are trimmed for PolyA or PolyT. In case of paired-end sequencing, Read2 is trimmed for the complementary base from the start of the reads.
+    | 
+    | PLEASE NOTE: The poly-A trimming mode expects that sequences were both adapter and quality trimmed before looking for Poly-A tails, and it is the user's responsibility to carry out an initial round of trimming.
+    |
+    | *option --polyA*
+
+* **Amplicon mode**
+
+    | This is a special mode of operation for paired-end data, such as required for the IMPLICON method, where a UMI sequence is getting transferred from the start of Read 2 to the readID of both reads. Following this, Trim Galore will exit.
+    | 
+    | In it's current implementation, the UMI carrying reads come in the following format:
+    |
+    | Read 1  5' FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF 3'
+    | Read 2  3' UUUUUUUUFFFFFFFFFFFFFFFFFFFFFFFFFFFF 5'
+    |
+    | Where UUUUUUUU is a random 8-mer unique molecular identifier (UMI) and FFFFFFF... is the actual fragment to be sequenced.
+    |
+    | *option --amplicon*
+
+.. _Trim Galore!: http://www.bioinformatics.babraham.ac.uk/projects/trim_galore/
+.. _Multi-tissue DNA methylation age predictor in mouse: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1203-5
+
     ]]></help>
-    <citations></citations>
+    <expand macro="citations" />
 </tool>